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Conserved domains on  [gi|937350038|ref|WP_054572090|]
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MULTISPECIES: AraC family transcriptional regulator [Pseudomonas]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 13722860)

AraC family transcriptional regulator contains a helix-turn-helix DNA-binding motif and controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Gene Ontology:  GO:0003700|GO:0006355|GO:0043565

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 31-183 9.16e-47

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


:

Pssm-ID: 461994  Cd Length: 152  Bit Score: 154.20  E-value: 9.16e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038   31 LPQVQVLSWDHYVASSPQIYEPSLMILAQGSKLARLGPRTLEYGAGHYLVQALSVPFMCE-TFATPEAPLLGVAVDIDRG 109
Cdd:pfam06719   2 IPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEvTEASPEEPYLGLALDLDPA 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 937350038  110 VLGELVQSMalaPDAAVQAQTPQSMTSAALDAPMRECVERLLRCLQDPVDAKVLGPARVREVLYTALRGPQAGV 183
Cdd:pfam06719  82 LLAELLLEA---PPPGPPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGAR 152
GlxA super family cl34854
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 160-293 1.59e-28

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


The actual alignment was detected with superfamily member COG4977:

Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 111.40  E-value: 1.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 160 AKVLGPARVREV-----LYTALRGPQAGVLRALVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKR 234
Cdd:COG4977  170 ERDHGAELANAVarrlvVDPRRPGGQAQFSPLLVPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRA 249

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 937350038 235 CTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGDE 293
Cdd:COG4977  250 ATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAY 308
 
Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 31-183 9.16e-47

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


Pssm-ID: 461994  Cd Length: 152  Bit Score: 154.20  E-value: 9.16e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038   31 LPQVQVLSWDHYVASSPQIYEPSLMILAQGSKLARLGPRTLEYGAGHYLVQALSVPFMCE-TFATPEAPLLGVAVDIDRG 109
Cdd:pfam06719   2 IPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEvTEASPEEPYLGLALDLDPA 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 937350038  110 VLGELVQSMalaPDAAVQAQTPQSMTSAALDAPMRECVERLLRCLQDPVDAKVLGPARVREVLYTALRGPQAGV 183
Cdd:pfam06719  82 LLAELLLEA---PPPGPPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGAR 152
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 160-293 1.59e-28

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 111.40  E-value: 1.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 160 AKVLGPARVREV-----LYTALRGPQAGVLRALVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKR 234
Cdd:COG4977  170 ERDHGAELANAVarrlvVDPRRPGGQAQFSPLLVPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRA 249

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 937350038 235 CTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGDE 293
Cdd:COG4977  250 ATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAY 308
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
211-292 3.24e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 90.69  E-value: 3.24e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038   211 PLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSP 290
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ..
gi 937350038   291 GD 292
Cdd:smart00342  81 SE 82
HTH_18 pfam12833
Helix-turn-helix domain;
217-292 3.57e-21

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 85.33  E-value: 3.57e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 937350038  217 LAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGE-GLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGD 292
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDtGLSVAEIALALGFSDASHFSRAFRRLFGLTPSE 77
ftrA PRK09393
transcriptional activator FtrA; Provisional
 177-291 6.87e-18

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 82.32  E-value: 6.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 177 RGPQAGVLRALVEQQGHfARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQML 256
Cdd:PRK09393 201 DGGQAQFVPRPVASRES-DRLGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLL 279

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 937350038 257 IGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPG 291
Cdd:PRK09393 280 ESSALSIDQIAERAGFGSEESLRHHFRRRAATSPA 314
 
Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 31-183 9.16e-47

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


Pssm-ID: 461994  Cd Length: 152  Bit Score: 154.20  E-value: 9.16e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038   31 LPQVQVLSWDHYVASSPQIYEPSLMILAQGSKLARLGPRTLEYGAGHYLVQALSVPFMCE-TFATPEAPLLGVAVDIDRG 109
Cdd:pfam06719   2 IPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEvTEASPEEPYLGLALDLDPA 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 937350038  110 VLGELVQSMalaPDAAVQAQTPQSMTSAALDAPMRECVERLLRCLQDPVDAKVLGPARVREVLYTALRGPQAGV 183
Cdd:pfam06719  82 LLAELLLEA---PPPGPPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGAR 152
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 160-293 1.59e-28

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 111.40  E-value: 1.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 160 AKVLGPARVREV-----LYTALRGPQAGVLRALVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKR 234
Cdd:COG4977  170 ERDHGAELANAVarrlvVDPRRPGGQAQFSPLLVPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRA 249

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 937350038 235 CTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGDE 293
Cdd:COG4977  250 ATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFRRRFGVSPSAY 308
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
211-292 3.24e-23

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 90.69  E-value: 3.24e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038   211 PLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSP 290
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ..
gi 937350038   291 GD 292
Cdd:smart00342  81 SE 82
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
145-292 2.86e-22

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 93.31  E-value: 2.86e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 145 ECVERLLRCLQDPVDAKVLGPARVREVLYTALRGPQAGVLRALVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMS 224
Cdd:COG2207  102 LLLLLLLLLLLLLLLLLLLLLLLLLLLALLRALELLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLS 181

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 937350038 225 VSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGD 292
Cdd:COG2207  182 PRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSE 249
HTH_18 pfam12833
Helix-turn-helix domain;
217-292 3.57e-21

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 85.33  E-value: 3.57e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 937350038  217 LAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGE-GLGVAQTAHRVGYQSTSQFSREYKRQFDRSPGD 292
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDtGLSVAEIALALGFSDASHFSRAFRRLFGLTPSE 77
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 190-292 3.40e-18

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 83.56  E-value: 3.40e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 190 QQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQmLIGEGLGVAQTAHR 269
Cdd:COG2169   79 SPPRADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQ-LLQTGLSVTDAAYA 157

                         90       100
                 ....*....|....*....|...
gi 937350038 270 VGYQSTSQFSREYKRQFDRSPGD 292
Cdd:COG2169  158 AGFGSLSRFYEAFKKLLGMTPSA 180
ftrA PRK09393
transcriptional activator FtrA; Provisional
 177-291 6.87e-18

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 82.32  E-value: 6.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 177 RGPQAGVLRALVEQQGHfARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQML 256
Cdd:PRK09393 201 DGGQAQFVPRPVASRES-DRLGPLIDWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLL 279

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 937350038 257 IGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSPG 291
Cdd:PRK09393 280 ESSALSIDQIAERAGFGSEESLRHHFRRRAATSPA 314
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
195-292 1.68e-15

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 74.71  E-value: 1.68e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 195 ARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQS 274
Cdd:PRK13503 171 ARLNQLLAWLEDHFAEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGD 250

                         90
                 ....*....|....*...
gi 937350038 275 TSQFSREYKRQFDRSPGD 292
Cdd:PRK13503 251 SNHFSTLFRREFSWSPRD 268
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
206-292 1.89e-08

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 51.46  E-value: 1.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 206 EHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQ 285
Cdd:PRK10219  16 EHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQ 95


                 ....*..
gi 937350038 286 FDRSPGD 292
Cdd:PRK10219  96 FDRTPSD 102
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 188-292 4.91e-08

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 53.11  E-value: 4.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 188 VEQQGHFARIGAALAHLREHYTEP-LSVEALAARANMSVSTFHEHFKRCTDMApMQYLKRLRLLKAQQML--IGEGLGVA 264
Cdd:PRK09685 190 SVQPRRERQFQKVVALIDQSIQEEiLRPEWIAGELGISVRSLYRLFAEQGLVV-AQYIRNRRLDRCADDLrpAADDEKIT 268

                         90       100
                 ....*....|....*....|....*...
gi 937350038 265 QTAHRVGYQSTSQFSREYKRQFDRSPGD 292
Cdd:PRK09685 269 SIAYKWGFSDSSHFSTAFKQRFGVSPGE 296
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 204-245 6.59e-08

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 47.92  E-value: 6.59e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 937350038  204 LREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLK 245
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQYRH 42
PRK10130 PRK10130
HTH-type transcriptional regulator EutR;
154-290 1.91e-06

HTH-type transcriptional regulator EutR;


Pssm-ID: 182258 [Multi-domain]  Cd Length: 350  Bit Score: 48.76  E-value: 1.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 154 LQDPVDAKVLGPARVREVLyTALRGPQAGVLRALVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFK 233
Cdd:PRK10130 200 LHQPAVRKVLGDNLLMAMG-AMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNAFH 278

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 234 RCTDMAPMQYLKRLRLLKAQQMLI---GEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSP 290
Cdd:PRK10130 279 AILGIGPNAWLKRIRLNAVRRELIspwSQSTTVKDAAMQWGFWHLGQFATDYQQLFAEKP 338
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
197-290 1.37e-05

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 43.94  E-value: 1.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 197 IGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTS 276
Cdd:PRK11511  11 IHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQ 90

                         90
                 ....*....|....
gi 937350038 277 QFSREYKRQFDRSP 290
Cdd:PRK11511  91 TLTRTFKNYFDVPP 104
PRK15435 PRK15435
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
190-291 1.83e-04

bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;


Pssm-ID: 185333 [Multi-domain]  Cd Length: 353  Bit Score: 42.47  E-value: 1.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 190 QQGHFARIGAAlAHLREHYTePLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGeGLGVAQTAHR 269
Cdd:PRK15435  80 QQHRLDKITHA-CRLLEQET-PVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLREALAK-GESVTTSILN 156

                         90       100
                 ....*....|....*....|..
gi 937350038 270 VGYQSTSQfsreYKRQFDRSPG 291
Cdd:PRK15435 157 AGFPDSSS----YYRKADETLG 174
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
211-290 3.52e-04

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 41.58  E-value: 3.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 211 PLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFSREYKRQFDRSP 290
Cdd:PRK13502 192 PFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTP 271
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
187-292 1.16e-03

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 39.96  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 187 LVEQQGHFARIGAALAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQT 266
Cdd:PRK10572 175 ESLHPPMDPRVREACQYISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATI 254

                         90       100
                 ....*....|....*....|....*.
gi 937350038 267 AHRVGYQSTSQFSREYKRQFDRSPGD 292
Cdd:PRK10572 255 GRNVGYDDQLYFSRVFKKCTGASPSE 280
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
180-290 2.43e-03

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 38.84  E-value: 2.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 180 QAGVLRALveqqghfarigaaLAHLREHYTEPLSVEALAARANMSVSTFHEHFKRCTDMAPMQYLKRLRLLKAQQML--- 256
Cdd:PRK15121   3 QAGIIRDL-------------LIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALrlt 69

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 937350038 257 ---IgegLGVAqtahrVGYQSTSQ--FSREYKRQFDRSP 290
Cdd:PRK15121  70 srpI---LDIA-----LQYRFDSQqtFTRAFKKQFAQTP 100
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
232-290 6.22e-03

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 37.58  E-value: 6.22e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937350038 232 FKRCTDMAPMQYLKRLRLLKAQQMLIGEGLGVAQTAHRVGYQSTSQFS-----------REYKRQFDRSP 290
Cdd:PRK13501 213 FRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSavftreagmtpRDYRQRFIRSP 282
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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