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Conserved domains on  [gi|917519534|ref|WP_052125951|]
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metal ABC transporter ATP-binding protein [Meiothermus ruber]

Protein Classification

metal ABC transporter ATP-binding protein( domain architecture ID 11438190)

metal ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of metal substrates including zinc and manganese; similar to zinc import ATP-binding protein ZnuC

CATH:  3.40.50.300
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
15-257 1.79e-142

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 399.08  E-value: 1.79e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQ 94
Cdd:COG1121    3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIGYVPQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:COG1121   83 RAEVDWDFPITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYGERMRWG 254
Cdd:COG1121  163 LDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLVAHGPPEEVLTPENLSRAYGGPVALL 242

                 ...
gi 917519534 255 ERH 257
Cdd:COG1121  243 AHG 245
 
Name Accession Description Interval E-value
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
15-257 1.79e-142

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 399.08  E-value: 1.79e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQ 94
Cdd:COG1121    3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIGYVPQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:COG1121   83 RAEVDWDFPITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYGERMRWG 254
Cdd:COG1121  163 LDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLVAHGPPEEVLTPENLSRAYGGPVALL 242

                 ...
gi 917519534 255 ERH 257
Cdd:COG1121  243 AHG 245
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
20-232 1.79e-116

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 332.19  E-value: 1.79e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGSVD 99
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYVPQRRSID 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 100 WDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:cd03235   81 RDFPISVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPF 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASG 232
Cdd:cd03235  161 AGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRTVVASG 213
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
15-252 4.89e-76

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 231.70  E-value: 4.89e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR--IGY 91
Cdd:PRK15056   3 QQAGIVVNDVTVTWRNgHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKnlVAY 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK15056  83 VPQSEEVDWSFPVLVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQ 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYGERM 251
Cdd:PRK15056 163 VILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKGTVLASGPTETTFTAENLELAFSGVL 242

                 .
gi 917519534 252 R 252
Cdd:PRK15056 243 R 243
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
28-223 2.07e-64

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 199.38  E-value: 2.07e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslAQARKRIGYVPQRGSVDWDFPTSVL 107
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVR------RAGGARVAYVPQRSEVPDSLPLTVR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 108 DVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTE 187
Cdd:NF040873  76 DLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESR 155
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 917519534 188 EAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTL 223
Cdd:NF040873 156 ERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
39-248 6.74e-60

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 188.91  E-value: 6.74e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   39 LEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGSVDWDFPTSVLDVVMMGLYGQL 118
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPGKGWRHIGYVPQRHEFAWDFPISVAHTVMSGRTGHI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  119 GWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK 198
Cdd:TIGR03771  81 GWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIELA 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 917519534  199 KQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYG 248
Cdd:TIGR03771 161 GAGTAILMTTHDLAQAMATCDRVVLLNGRVIADGTPQQLQDPAPWMTTFG 210
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
36-180 2.86e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 133.54  E-value: 2.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----AQARKRIGYVPQrgsVDWDFP-TSVLDV 109
Cdd:pfam00005   3 NVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtdderKSLRKEIGYVFQ---DPQLFPrLTVREN 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534  110 VMMGLYGQlGWFKRPGPREREAAlrcLEQVSMQAFTTR----QISQLSGGQQQRVFLARALAQDADLYFMDEPFA 180
Cdd:pfam00005  80 LRLGLLLK-GLSKREKDARAEEA---LEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-183 8.86e-21

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 91.34  E-value: 8.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLikavLGLVPVA----SGQVRFFGQSLAQAR------KRI 89
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIAGArkiqQGRVEVLGGDMADARhrravcPRI 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQrG---------SV--DWDFptsvldvvmMG-LYGQlgwfkrpGPREREAAL-RCLEQVSMQAFTTRQISQLSGGQ 156
Cdd:NF033858  79 AYMPQ-GlgknlyptlSVfeNLDF---------FGrLFGQ-------DAAERRRRIdELLRATGLAPFADRPAGKLSGGM 141
                        170       180
                 ....*....|....*....|....*..
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:NF033858 142 KQKLGLCCALIHDPDLLILDEPTTGVD 168
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
33-212 2.51e-18

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 80.92  E-value: 2.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKaVLGLV-PVASGQVRFFG---------QSLAQARKRIGYVPQrgSVDWDF 102
Cdd:NF038007  20 VLNHLNFSVEKGDFVSIMGPSGSGKSTLLN-IIGMFdSLDSGSLTLAGkevtnlsysQKIILRRELIGYIFQ--SFNLIP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 PTSVLDVVMMGLygqlgwfKRPGPREREAALRCLEQVSMQAFTTR---QISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:NF038007  97 HLSIFDNVALPL-------KYRGVAKKERIERVNQVLNLFGIDNRrnhKPMQLSGGQQQRVAIARAMVSNPALLLADEPT 169
                        170       180       190
                 ....*....|....*....|....*....|...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:NF038007 170 GNLDSKNARAVLQQLKYINQKGTTIIMVTHSDE 202
GguA NF040905
sugar ABC transporter ATP-binding protein;
33-224 1.93e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 80.99  E-value: 1.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS--------GQVRFFG--------------QSLA------- 83
Cdd:NF040905  16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyegeilfdGEVCRFKdirdsealgiviihQELAlipylsi 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 ---------QARkrigyvpqRGSVDWDfptsvldvvmmglygqlgwfkrpgpREREAALRCLEQVSMQAFTTRQISQLSG 154
Cdd:NF040905  96 aeniflgneRAK--------RGVIDWN-------------------------ETNRRARELLAKVGLDESPDTLVTDIGV 142
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 155 GQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:NF040905 143 GKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVL 212
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
13-239 8.54e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 61.29  E-value: 8.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  13 SGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAG--KSTLIKAVLGlvPVASGQVRFFGQSLAQAR---K 87
Cdd:NF000106   8 NGARNAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G--PDAGRRPWRF*TWCANRRalrR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  88 RIG-YVPQRGSVDWDFpTSVLDVVMMGLYGQLgwfKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:NF000106  86 TIG*HRPVR*GRRESF-SGRENLYMIGR*LDL---SRKDARARADEL--LERFSLTEAAGRAAAKYSGGMRRRLDLAASM 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT 239
Cdd:NF000106 160 IGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRgRVIADGKVDELKT 233
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
44-216 2.88e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 57.38  E-value: 2.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    44 GQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGqslaqarkrigyvpqrgsvdwdfptsvldvvmmglygqlgwfkr 123
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYID-------------------------------------------- 37
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   124 pGPREREAALRCLEQVsmqaFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLH------EL 197
Cdd:smart00382  38 -GEDILEEVLDQLLLI----IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrllllLK 112
                          170
                   ....*....|....*....
gi 917519534   198 KKQGKTVVVVHHDLETVRD 216
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGP 131
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
36-209 1.22e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 58.21  E-value: 1.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYVPQRGSvdwdfptsvldvvm 111
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDagdiATRRRVGYMSQAFS-------------- 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 mgLYGQLG----------WFKRP----GPREREAALRC-LEQVsMQAFTtrqiSQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:NF033858 350 --LYGELTvrqnlelharLFHLPaaeiAARVAEMLERFdLADV-ADALP----DSLPLGIRQRLSLAVAVIHKPELLILD 422
                        170       180       190
                 ....*....|....*....|....*....|....
gi 917519534 177 EPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHH 209
Cdd:NF033858 423 EPTSGVDPVARDMFWRLLIELsREDGVTIFISTH 456
GguA NF040905
sugar ABC transporter ATP-binding protein;
152-207 1.11e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.94  E-value: 1.11e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 152 LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV 207
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVI 460
 
Name Accession Description Interval E-value
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
15-257 1.79e-142

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 399.08  E-value: 1.79e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQ 94
Cdd:COG1121    3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIGYVPQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:COG1121   83 RAEVDWDFPITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLLL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYGERMRWG 254
Cdd:COG1121  163 LDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLVAHGPPEEVLTPENLSRAYGGPVALL 242

                 ...
gi 917519534 255 ERH 257
Cdd:COG1121  243 AHG 245
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
20-232 1.79e-116

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 332.19  E-value: 1.79e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGSVD 99
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIGYVPQRRSID 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 100 WDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:cd03235   81 RDFPISVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPF 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASG 232
Cdd:cd03235  161 AGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRTVVASG 213
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
19-252 7.04e-86

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 256.12  E-value: 7.04e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-----QARKRIGYVP 93
Cdd:COG1120    2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLAslsrrELARRIAYVP 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRGSVDWDFptSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLY 173
Cdd:COG1120   82 QEPPAPFGL--TVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 174 FMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKRTYGERM 251
Cdd:COG1120  160 LLDEPTSHLDLAHQLEVLELLRRLaRERGRTVVMVLHDLNLAARYADRLVLLkDGRIVAQGPPEEVLTPELLEEVYGVEA 239

                 .
gi 917519534 252 R 252
Cdd:COG1120  240 R 240
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
15-252 4.89e-76

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 231.70  E-value: 4.89e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR--IGY 91
Cdd:PRK15056   3 QQAGIVVNDVTVTWRNgHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKnlVAY 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK15056  83 VPQSEEVDWSFPVLVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQ 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYGERM 251
Cdd:PRK15056 163 VILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKGTVLASGPTETTFTAENLELAFSGVL 242

                 .
gi 917519534 252 R 252
Cdd:PRK15056 243 R 243
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
19-237 5.33e-68

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 209.92  E-value: 5.33e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYVPQ 94
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVArdpaEVRRRIGYVPQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFptSVLDVVMM--GLYGqlgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG1131   81 EPALYPDL--TVRENLRFfaRLYG------LPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPEL 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEV 237
Cdd:COG1131  153 LILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKgRIVADGTPDEL 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
28-223 2.07e-64

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 199.38  E-value: 2.07e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslAQARKRIGYVPQRGSVDWDFPTSVL 107
Cdd:NF040873   2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVR------RAGGARVAYVPQRSEVPDSLPLTVR 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 108 DVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTE 187
Cdd:NF040873  76 DLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESR 155
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 917519534 188 EAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTL 223
Cdd:NF040873 156 ERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
19-249 7.37e-64

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 199.90  E-value: 7.37e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS--------LAQARKRI 89
Cdd:COG3638    3 LELRNLSKRYPgGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDvtalrgraLRRLRRRI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQrgsvdwDFP----TSVLDVVMMGLYGQLG----WFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:COG3638   83 GMIFQ------QFNlvprLSVLTNVLAGRLGRTStwrsLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVA 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVfT 239
Cdd:COG3638  157 IARALVQEPKLILADEPVASLDPKTARQVMDLLRRIaREDGITVVVNLHQVDLARRYADRIIGLRDgRVVFDGPPAEL-T 235
                        250
                 ....*....|
gi 917519534 240 PENLKRTYGE 249
Cdd:COG3638  236 DAVLREIYGG 245
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
19-252 1.86e-62

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 196.49  E-value: 1.86e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRiGYV 92
Cdd:COG4559    2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAwspwelARRR-AVL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwDFPTSVLDVVMMGLYGQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ---- 168
Cdd:COG4559   81 PQHSSL--AFPFTVEEVVALGRAPHG----SSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAQlwep 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 ---DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLK 244
Cdd:COG4559  155 vdgGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLhQGRLVAQGTPEEVLTDELLE 234

                 ....*...
gi 917519534 245 RTYGERMR 252
Cdd:COG4559  235 RVYGADLR 242
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
19-248 1.87e-61

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 193.76  E-value: 1.87e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQ-VRFFGQ-----SLAQARKRIGYV 92
Cdd:COG1119    4 LELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdVRLFGErrggeDVWELRKRIGLV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgSVDWDFP--TSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:COG1119   84 SP--ALQLRFPrdETVLDVVLSGFFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDP 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQG-KTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKRTYG 248
Cdd:COG1119  162 ELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLkDGRVVAAGPKEEVLTSENLSEAFG 241
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
39-248 6.74e-60

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 188.91  E-value: 6.74e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   39 LEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGSVDWDFPTSVLDVVMMGLYGQL 118
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPGKGWRHIGYVPQRHEFAWDFPISVAHTVMSGRTGHI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  119 GWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK 198
Cdd:TIGR03771  81 GWLRRPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIELA 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 917519534  199 KQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENLKRTYG 248
Cdd:TIGR03771 161 GAGTAILMTTHDLAQAMATCDRVVLLNGRVIADGTPQQLQDPAPWMTTFG 210
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
19-245 3.86e-59

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 187.15  E-value: 3.86e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGYV 92
Cdd:COG1122    1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKditkkNLRELRRKVGLV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgsvdwdFP------TSVLDVVMMGLYgQLGWfkrpgPRE--REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLAR 164
Cdd:COG1122   81 FQ-------NPddqlfaPTVEEDVAFGPE-NLGL-----PREeiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAG 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 165 ALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT-PEN 242
Cdd:COG1122  148 VLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDgRIVADGTPREVFSdYEL 227

                 ...
gi 917519534 243 LKR 245
Cdd:COG1122  228 LEE 230
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
20-232 6.15e-58

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 182.25  E-value: 6.15e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-----QARKRIGYVPQ 94
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLAslspkELARKIAYVPQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 rgsvdwdfptsvldvvmmglygqlgwfkrpgprereaalrCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03214   81 ----------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILL 120
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASG 232
Cdd:cd03214  121 LDEPTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLkDGRIVAQG 180
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
19-247 1.38e-56

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 181.23  E-value: 1.38e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA--------QARKRI 89
Cdd:cd03256    1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINklkgkalrQLRRQI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQrgsvdwDFP----TSVLDVVMMGLYGQL----GWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:cd03256   81 GMIFQ------QFNlierLSVLENVLSGRLGRRstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVA 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEvFT 239
Cdd:cd03256  155 IARALMQQPKLILADEPVASLDPASSRQVMDLLKRInREEGITVIVSLHQVDLAREYADRIVGLKDgRIVFDGPPAE-LT 233

                 ....*...
gi 917519534 240 PENLKRTY 247
Cdd:cd03256  234 DEVLDEIY 241
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
19-212 2.47e-56

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 179.59  E-value: 2.47e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQ 94
Cdd:cd03293    1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDRGYVFQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVdwdFP-TSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLY 173
Cdd:cd03293   81 QDAL---LPwLTVLDNVALGLELQ----GVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVL 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 917519534 174 FMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:cd03293  154 LLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHDID 193
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
20-225 2.85e-56

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 179.20  E-value: 2.85e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGYV 92
Cdd:cd03225    1 ELKNLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKdltklSLKELRRKVGLV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgsvdwdFP------TSVLDVVMMGLyGQLGWfkrPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:cd03225   81 FQ-------NPddqffgPTVEEEVAFGL-ENLGL---PEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVL 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03225  150 AMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLE 208
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
19-237 1.02e-55

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 178.78  E-value: 1.02e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGlppheiARLGIGRT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMGLYGQLG---WFKRPGPREREA---ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARA 165
Cdd:cd03219   81 FQIPRL---FPElTVLENVMVAAQARTGsglLLARARREEREArerAEELLERVGLADLADRPAGELSYGQQRRLEIARA 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEV 237
Cdd:cd03219  158 LATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQgRVIAEGTPDEV 230
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
19-248 7.09e-54

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 174.57  E-value: 7.09e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRiGYV 92
Cdd:PRK13548   3 LEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADwspaelARRR-AVL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwDFPTSVLDVVMMGLYGqlgwFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD- 171
Cdd:PRK13548  82 PQHSSL--SFPFTVEEVVAMGRAP----HGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQLWEp 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 172 -----LYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLK 244
Cdd:PRK13548 156 dgpprWLLLDEPTSALDLAHQHHVLRLARQLaHERGLAVIVVLHDLNLAARYADRIVLLhQGRLVADGTPAEVLTPETLR 235

                 ....
gi 917519534 245 RTYG 248
Cdd:PRK13548 236 RVYG 239
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
19-225 7.10e-54

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 171.81  E-value: 7.10e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL----AQARKRIGYVPQ 94
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIkkepEEVKRRIGYLPE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RgsvdwdfptsvldvvmMGLYGQLgwfkrpgprereaalrcleqvsmqafTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03230   81 E----------------PSLYENL--------------------------TVRENLKLSGGMKQRLALAQALLHDPELLI 118
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03230  119 LDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILN 169
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
19-242 8.30e-53

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 171.32  E-value: 8.30e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------RKRIG 90
Cdd:COG1127    6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLsekelyelRRRIG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRG----SVdwdfptSVLDVVMMGL--YGQLgwfkrpgPRE--REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFL 162
Cdd:COG1127   86 MLFQGGalfdSL------TVFENVAFPLreHTDL-------SEAeiRELVLEKLELVGLPGAADKMPSELSGGMRKRVAL 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTP 240
Cdd:COG1127  153 ARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLaDGKIIAEGTPEELLAS 232

                 ..
gi 917519534 241 EN 242
Cdd:COG1127  233 DD 234
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
19-247 1.26e-52

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 170.81  E-value: 1.26e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYVPQ 94
Cdd:COG4555    2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRkeprEARRQIGVLPD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 -RGSVDWdfpTSVLDVVMMglygqLGWFKRPGPREREAAL-RCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG4555   82 eRGLYDR---LTVRENIRY-----FAELYGLFDEELKKRIeELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKV 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV---FTPENLKRTY 247
Cdd:COG4555  154 LLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILhKGKVVAQGSLDELreeIGEENLEDAF 232
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
13-212 4.18e-52

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 170.27  E-value: 4.18e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  13 SGASSPLRVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR 88
Cdd:COG1116    2 SAAAPALELRGVSKRFPtgggGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVdwdFP-TSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALA 167
Cdd:COG1116   82 RGVVFQEPAL---LPwLTVLDNVALGLELR----GVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALA 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:COG1116  155 NDPEVLLMDEPFGALDALTRERLQDELLRLwQETGKTVLFVTHDVD 200
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
3-236 7.15e-51

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 174.56  E-value: 7.15e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   3 TQPKTVQHPESGASSpLRVRDLTVVY-REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS 81
Cdd:COG4988  322 APAGTAPLPAAGPPS-IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVD 400
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  82 LAQA-----RKRIGYVPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQVSMQAFTTR-------QI 149
Cdd:COG4988  401 LSDLdpaswRRQIAWVPQNPYL---FAGTIRENLRLG---------RPDASD-EELEAALEAAGLDEFVAAlpdgldtPL 467
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 150 ----SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:COG4988  468 geggRGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK-GRTVILITHRLALLAQADRILVLDD 546
                        250
                 ....*....|.
gi 917519534 226 VQVIASGPMEE 236
Cdd:COG4988  547 GRIVEQGTHEE 557
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
19-242 1.71e-50

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 165.37  E-value: 1.71e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS--------LAQARKRIG 90
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDisglseaeLYRLRRRMG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRGSVdwdFPT-SVLDVVMMGLYGQlgwFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:cd03261   81 MLFQSGAL---FDSlTVFENVAFPLREH---TRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALD 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPEN 242
Cdd:cd03261  155 PELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLyDGKIVAEGTPEELRASDD 229
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
19-237 2.42e-50

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 165.60  E-value: 2.42e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:COG0411    5 LEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGlpphriARLGIART 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMGLYGQLG------WFKRPGPREREAALR-----CLEQVSMQAFTTRQISQLSGGQQQRV 160
Cdd:COG0411   85 FQNPRL---FPElTVLENVLVAAHARLGrgllaaLLRLPRARREEREAReraeeLLERVGLADRADEPAGNLSYGQQRRL 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKK-QGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEV 237
Cdd:COG0411  162 EIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDeRGITILLIEHDMDLVMGLADRIVVLDFgRVIAEGTPAEV 240
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
20-225 3.45e-50

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 162.03  E-value: 3.45e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIGYVPQ 94
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKlpleeLRRRIGYVPQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 rgsvdwdfptsvldvvmmglygqlgwfkrpgprereaalrcleqvsmqafttrqisqLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd00267   81 ---------------------------------------------------------LSGGQRQRVALARALLLNPDLLL 103
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd00267  104 LDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLK 154
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
17-248 5.66e-50

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 164.42  E-value: 5.66e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  17 SPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--AR---KRIGY 91
Cdd:PRK11231   1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMlsSRqlaRRLAL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWDFptSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK11231  81 LPQHHLTPEGI--TVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTP 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKRTYG 248
Cdd:PRK11231 159 VVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLaNGHVMAQGTPEEVMTPGLLRTVFD 236
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
18-250 1.08e-49

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 168.10  E-value: 1.08e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGYV 92
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDdvealSARAASRRVASV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:PRK09536  83 PQDTSLSFEF--DVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPV 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKRTYGER 250
Cdd:PRK09536 161 LLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLaDGRVRAAGPPADVLTADTLRAAFDAR 239
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
19-219 1.76e-49

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 161.89  E-value: 1.76e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------- 85
Cdd:cd03255    1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekelaafr 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RKRIGYVPQrgsvdwDF---PT-SVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:cd03255   81 RRHIGFVFQ------SFnllPDlTALENVELPLLLA----GVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVA 150
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRdYFD 219
Cdd:cd03255  151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAE-YAD 208
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
2-239 4.80e-49

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 168.93  E-value: 4.80e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   2 ITQPKTVQHPESGASSP-LRVRDLTVVY-----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQV 75
Cdd:COG1123  243 LGAARGRAAPAAAAAEPlLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSI 322
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  76 RFFGQ--------SLAQARKRIGYVPQ--RGSVDwdfPT-SVLDVVMMGL--YGQLgwfkrPGPREREAALRCLEQVSMQ 142
Cdd:COG1123  323 LFDGKdltklsrrSLRELRRRVQMVFQdpYSSLN---PRmTVGDIIAEPLrlHGLL-----SRAERRERVAELLERVGLP 394
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 143 A-FTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDH 220
Cdd:COG1123  395 PdLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFISHDLAVVRYIADR 474
                        250       260
                 ....*....|....*....|
gi 917519534 221 LTLLNV-QVIASGPMEEVFT 239
Cdd:COG1123  475 VAVMYDgRIVEDGPTEEVFA 494
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
19-248 5.16e-49

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 161.70  E-value: 5.16e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVY-REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------RKRI 89
Cdd:TIGR02315   2 LEVENLSKVYpNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLrgkklrklRRRI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   90 GYVPQrgsvdwDF----PTSVLDVVMMGLYGQ-------LGWFKRpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQ 158
Cdd:TIGR02315  82 GMIFQ------HYnlieRLTVLENVLHGRLGYkptwrslLGRFSE---EDKERALSALERVGLADKAYQRADQLSGGQQQ 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEE 236
Cdd:TIGR02315 153 RVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRInKEDGITVIINLHQVDLAKKYADRIVGLKAgEIVFDGAPSE 232
                         250
                  ....*....|..
gi 917519534  237 VfTPENLKRTYG 248
Cdd:TIGR02315 233 L-DDEVLRHIYG 243
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
19-220 1.28e-48

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 158.32  E-value: 1.28e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGY 91
Cdd:cd03228    1 IEFKNVSFSYpgRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLdleslRKNIAY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFPTSVLDVVmmglygqlgwfkrpgprereaalrcleqvsmqafttrqisqLSGGQQQRVFLARALAQDAD 171
Cdd:cd03228   81 VPQDPFL---FSGTIRENI-----------------------------------------LSGGQRQRIAIARALLRDPP 116
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDyFDH 220
Cdd:cd03228  117 ILILDEATSALDPETEALILEALRALAK-GKTVIVIAHRLSTIRD-ADR 163
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
19-247 2.18e-48

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 159.76  E-value: 2.18e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:COG0410    4 LEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGlpphriARLGIGYV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMGLYGqlgwfkRPGPREREAAlrcLEQVsMQAF------TTRQISQLSGGQQQRVFLARA 165
Cdd:COG0410   84 PEGRRI---FPSlTVEENLLLGAYA------RRDRAEVRAD---LERV-YELFprlkerRRQRAGTLSGGEQQMLAIGRA 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENLK 244
Cdd:COG0410  151 LMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERgRIVLEGTAAELLADPEVR 230

                 ...
gi 917519534 245 RTY 247
Cdd:COG0410  231 EAY 233
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
19-237 2.77e-48

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 159.14  E-value: 2.77e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA------QARKRIGYV 92
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITglppheRARAGIGYV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMGLYGQlgwFKRPGPREREAAL----RCLEQVSMQAfttrqiSQLSGGQQQRVFLARALA 167
Cdd:cd03224   81 PEGRRI---FPElTVEENLLLGAYAR---RRAKRKARLERVYelfpRLKERRKQLA------GTLSGGEQQMLAIARALM 148
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:cd03224  149 SRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLeRGRVVLEGTAAEL 219
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
19-212 8.00e-48

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 157.68  E-value: 8.00e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ---ARKRIGYVPQR 95
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGvppERRNIGMVFQD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFPT-SVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03259   81 YAL---FPHlTVAENIAFGLKLR----GVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLL 153
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:cd03259  154 LDEPLSALDAKLREELREELKELqRELGITTIYVTHDQE 192
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
19-221 1.11e-47

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 157.67  E-value: 1.11e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------R 86
Cdd:cd03257    2 LEVKNLSVSFPTGggsvKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLsrrlrkirR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQ--RGSVDwdfPT-SVLDVVMMGLYGQLGwfKRPGPREREAALRCLEQVSM-QAFTTRQISQLSGGQQQRVFL 162
Cdd:cd03257   82 KEIQMVFQdpMSSLN---PRmTIGEQIAEPLRIHGK--LSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAI 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHL 221
Cdd:cd03257  157 ARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRV 216
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
19-212 1.29e-47

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 156.87  E-value: 1.29e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA----RKRIGYVPQ 94
Cdd:COG4133    3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAredyRRRLAYLGH 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFptSVLDvvmmglygQLGWFKR--PGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG4133   83 ADGLKPEL--TVRE--------NLRFWAAlyGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPL 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV-HHDLE 212
Cdd:COG4133  153 WLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTtHQPLE 193
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
1-236 1.69e-47

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 165.71  E-value: 1.69e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   1 MITQPKTVQHPESGASSP----LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQ 74
Cdd:COG4987  312 LLDAPPAVTEPAEPAPAPggpsLELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGS 391
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  75 VRFFGQSL-----AQARKRIGYVPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQVSMQAFTTRQI 149
Cdd:COG4987  392 ITLGGVDLrdldeDDLRRRIAVVPQRPHL---FDTTLRENLRLA---------RPDATD-EELWAALERVGLGDWLAALP 458
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 150 -----------SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVrDYF 218
Cdd:COG4987  459 dgldtwlgeggRRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEA-LAGRTVLLITHRLAGL-ERM 536
                        250
                 ....*....|....*....
gi 917519534 219 DH-LTLLNVQVIASGPMEE 236
Cdd:COG4987  537 DRiLVLEDGRIVEQGTHEE 555
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
19-220 1.85e-47

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 157.13  E-value: 1.85e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------- 85
Cdd:COG1136    5 LELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLserelarlr 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RKRIGYVPQrgsvdwDF---PT-SVLDVVMMGLYgqlgwFKRPGPREREA-ALRCLEQVSMQAFTTRQISQLSGGQQQRV 160
Cdd:COG1136   85 RRHIGFVFQ------FFnllPElTALENVALPLL-----LAGVSRKERRErARELLERVGLGDRLDHRPSQLSGGQQQRV 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLEtVRDYFDH 220
Cdd:COG1136  154 AIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELnRELGTTIVMVTHDPE-LAARADR 213
F420-0_ABC_ATP TIGR03873
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ...
19-250 3.21e-47

proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163585 [Multi-domain]  Cd Length: 256  Bit Score: 157.67  E-value: 3.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL----AQAR-KRIGYVP 93
Cdd:TIGR03873   2 LRLSRVSWSAGGRLIVDGVDVTAPPGSLTGLLGPNGSGKSTLLRLLAGALRPDAGTVDLAGVDLhglsRRARaRRVALVE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   94 QrgSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLY 173
Cdd:TIGR03873  82 Q--DSDTAVPLTVRDVVALGRIPHRSLWAGDSPHDAAVVDRALARTELSHLADRDMSTLSGGERQRVHVARALAQEPKLL 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534  174 FMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENLKRTYGER 250
Cdd:TIGR03873 160 LLDEPTNHLDVRAQLETLALVRELAATGVTVVAALHDLNLAASYCDHVVVLDGgRVVAAGPPREVLTPALIRAVYGVD 237
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
19-239 5.63e-47

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 163.15  E-value: 5.63e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSLAQAR-----KR 88
Cdd:COG1123    5 LEVRDLSVRYPggDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPhggRISGEVLLDGRDLLELSealrgRR 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVDWDfPTSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:COG1123   85 IGMVFQDPMTQLN-PVTVGDQIAEALENL----GLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT 239
Cdd:COG1123  160 DPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDgRIVEDGPPEEILA 232
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
19-251 7.18e-47

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 157.96  E-value: 7.18e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-RKRIGYVPQ-Rg 96
Cdd:COG4152    2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEdRRRIGYLPEeR- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 svdwdfptsvldvvmmGLYG------QLGWFKR----PGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:COG4152   81 ----------------GLYPkmkvgeQLVYLARlkglSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAAL 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVftpenlKR 245
Cdd:COG4152  145 LHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKgRKVLSGSVDEI------RR 218

                 ....*.
gi 917519534 246 TYGERM 251
Cdd:COG4152  219 QFGRNT 224
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
20-248 6.05e-46

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 154.09  E-value: 6.05e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQAR-----KRIGYVPQ 94
Cdd:COG4604    3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPsrelaKRLAILRQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 rgsvDWDFPT--SVLDVVMMGLY----GqlgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:COG4604   83 ----ENHINSrlTVRELVAFGRFpyskG------RLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQ 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 DADLYFMDEPFAGVD---AVteeAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENL 243
Cdd:COG4604  153 DTDYVLLDEPLNNLDmkhSV---QMMKLLRRLaDELGKTVVIVLHDINFASCYADHIVAMkDGRVVAQGTPEEIITPEVL 229

                 ....*
gi 917519534 244 KRTYG 248
Cdd:COG4604  230 SDIYD 234
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
19-223 7.69e-46

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 152.28  E-value: 7.69e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYVP 93
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMpppewRRQVAYVP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRgsVDWdFPTSVLDVVmmglygQLGWFKRPGPREREAALRCLEQVSMQA-FTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG4619   81 QE--PAL-WGGTVRDNL------PFPFQLRERKFDRERALELLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDV 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFD-HLTL 223
Cdd:COG4619  152 LLLDEPTSALDPENTRRVEELLREYlAEEGRAVLWVSHDPEQIERVADrVLTL 204
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
19-237 2.17e-44

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 158.84  E-value: 2.17e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGY 91
Cdd:COG2274  474 IELENVSFRYpgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIdpaslRRQIGV 553
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQVSMQAFTTR-------QI----SQLSGGQQQRV 160
Cdd:COG2274  554 VLQDVFL---FSGTIRENITLG---------DPDATD-EEIIEAARLAGLHDFIEAlpmgydtVVgeggSNLSGGQRQRL 620
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRDyFD-HLTLLNVQVIASGPMEEV 237
Cdd:COG2274  621 AIARALLRNPRILILDEATSALDAETEAIILENLRRL-LKGRTVIIIAHRLSTIRL-ADrIIVLDKGRIVEDGTHEEL 696
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
19-225 8.07e-44

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 147.43  E-value: 8.07e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-AQARKRIGYVPQ-RG 96
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLdIAARNRIGYLPEeRG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 SvdwdFP-TSVLDVVMMglYGQLgwfKRPGPRE-REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03269   81 L----YPkMKVIDQLVY--LAQL---KGLKKEEaRRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03269  152 LDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLN 202
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
15-212 1.67e-43

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 150.63  E-value: 1.67e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKR-IGY 91
Cdd:COG3842    2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGlpPEKRnVGM 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFP-TSVLDVVMMGLYgqlgwFKRPGPREREA-ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:COG3842   82 VFQDYAL---FPhLTVAENVAFGLR-----MRGVPKAEIRArVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPE 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:COG3842  154 PRVLLLDEPLSALDAKLREEMREELRRLqRELGITFIYVTHDQE 197
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
19-225 2.00e-43

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 145.41  E-value: 2.00e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-------QARKRIGY 91
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTdledelpPLRRRIGM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFPT-SVLDVVMMGlygqlgwfkrpgprereaalrcleqvsmqafttrqisqLSGGQQQRVFLARALAQDA 170
Cdd:cd03229   81 VFQDFAL---FPHlTVLENIALG--------------------------------------LSGGQQQRVALARALAMDP 119
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03229  120 DVLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLR 175
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
19-246 2.09e-43

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 147.26  E-value: 2.09e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRI 89
Cdd:COG1124    2 LEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRrrkafRRRV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQ--RGSVDwdfPT-SVLDVVMMGLYGQlgwfKRPGPREREAALrcLEQVSM-QAFTTRQISQLSGGQQQRVFLARA 165
Cdd:COG1124   82 QMVFQdpYASLH---PRhTVDRILAEPLRIH----GLPDREERIAEL--LEQVGLpPSFLDRYPHQLSGGQRQRVAIARA 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHltllnVQVIASGPMEEVFTPENLK 244
Cdd:COG1124  153 LILEPELLLLDEPTSALDVSVQAEILNLLKDLREErGLTYLFVSHDLAVVAHLCDR-----VAVMQNGRIVEELTVADLL 227

                 ..
gi 917519534 245 RT 246
Cdd:COG1124  228 AG 229
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
19-238 1.11e-40

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 140.02  E-value: 1.11e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQAR 86
Cdd:cd03258    2 IELKNVSKVFgdtgGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTdltllsgkELRKAR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSVDWDfpTSVLDVVMMGLygQLGwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:cd03258   82 RRIGMIFQHFNLLSS--RTVFENVALPL--EIA--GVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARAL 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVF 238
Cdd:cd03258  156 ANNPKVLLCDEATSALDPETTQSILALLRDInRELGLTIVLITHEMEVVKRICDRVAVMeKGEVVEEGTVEEVF 229
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
19-246 2.70e-40

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 139.36  E-value: 2.70e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYV 92
Cdd:cd03295    1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQdpvelRRKIGYV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFP-TSVLDVVmmGLYGQL-GWfkrPGPREREAALRCLEQVSM--QAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:cd03295   81 IQQIGL---FPhMTVEENI--ALVPKLlKW---PKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAA 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNvqviaSGPMEEVFTPENLKRT 246
Cdd:cd03295  153 DPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMK-----NGEIVQVGTPDEILRS 226
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
19-225 6.10e-40

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 137.22  E-value: 6.10e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY-----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGqslaqarkRIGYVP 93
Cdd:cd03250    1 ISVEDASFTWdsgeqETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--------SIAYVS 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QrgsVDWDFPTSVLDVVMMGlygqlgwfkRPGPRER-EAALR--CLEQvSMQAFT----T----RQISqLSGGQQQRVFL 162
Cdd:cd03250   73 Q---EPWIQNGTIRENILFG---------KPFDEERyEKVIKacALEP-DLEILPdgdlTeigeKGIN-LSGGQKQRISL 138
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILR--VLHELKKqGKTVVVVHHDLETVRdYFDHLTLLN 225
Cdd:cd03250  139 ARAVYSDADIYLLDDPLSAVDAHVGRHIFEncILGLLLN-NKTRILVTHQLQLLP-HADQIVVLD 201
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
19-217 1.00e-39

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 137.11  E-value: 1.00e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------RKRI 89
Cdd:COG2884    2 IRFENVSKRYPGgREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLkrreipylRRRI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQrgsvdwDFP----TSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARA 165
Cdd:COG2884   82 GVVFQ------DFRllpdRTVYENVALPLRVT----GKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARA 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:COG2884  152 LVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRM 203
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
20-212 1.98e-39

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 138.69  E-value: 1.98e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYVP 93
Cdd:COG1125    3 EFENVTKRYPDgTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLdpvelRRRIGYVI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRGSVdwdFPT-SVLDVVMM--GLygqLGWFKRpgpREREAALRCLEQVSMQA--FTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:COG1125   83 QQIGL---FPHmTVAENIATvpRL---LGWDKE---RIRARVDELLELVGLDPeeYRDRYPHELSGGQQQRVGVARALAA 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 917519534 169 DADLYFMDEPFAGVDAVTEEA----ILRVLHELkkqGKTVVVVHHDLE 212
Cdd:COG1125  154 DPPILLMDEPFGALDPITREQlqdeLLRLQREL---GKTIVFVTHDID 198
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
3-224 2.06e-39

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 143.20  E-value: 2.06e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    3 TQPKTVQHP-ESGASSPLRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ 80
Cdd:TIGR02857 305 PRPLAGKAPvTAAPASSLEFSGVSVAYPgRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGV 384
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   81 SLAQA-----RKRIGYVPQRgsvDWDFPTSVLDVVMMGlygqlgwfkRPGPRE---REAALRC----LEQVSMQAFTTR- 147
Cdd:TIGR02857 385 PLADAdadswRDQIAWVPQH---PFLFAGTIAENIRLA---------RPDASDaeiREALERAgldeFVAALPQGLDTPi 452
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534  148 --QISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRDYfDHLTLL 224
Cdd:TIGR02857 453 geGGAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTHRLALAALA-DRIVVL 529
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
36-180 2.86e-39

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 133.54  E-value: 2.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----AQARKRIGYVPQrgsVDWDFP-TSVLDV 109
Cdd:pfam00005   3 NVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtdderKSLRKEIGYVFQ---DPQLFPrLTVREN 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534  110 VMMGLYGQlGWFKRPGPREREAAlrcLEQVSMQAFTTR----QISQLSGGQQQRVFLARALAQDADLYFMDEPFA 180
Cdd:pfam00005  80 LRLGLLLK-GLSKREKDARAEEA---LEKLGLGDLADRpvgeRPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
1-216 6.76e-39

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 142.23  E-value: 6.76e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   1 MITQPKTVQHPESGASSP-----LRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQ 74
Cdd:COG1132  317 LLDEPPEIPDPPGAVPLPpvrgeIEFENVSFSYPgDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGR 396
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  75 VRFFGQ-----SLAQARKRIGYVPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGpREREAALRCLEQVSMQAFTTR-- 147
Cdd:COG1132  397 ILIDGVdirdlTLESLRRQIGVVPQDTFL---FSGTIRENIRYG---------RPD-ATDEEVEEAAKAAQAHEFIEAlp 463
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 148 -----QISQ----LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRD 216
Cdd:COG1132  464 dgydtVVGErgvnLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMK-GRTTIVIAHRLSTIRN 540
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
19-212 8.46e-39

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 134.55  E-value: 8.46e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYV 92
Cdd:cd03263    1 LQIRNLTKTYkkGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRtdrkAARQSLGYC 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDVVMmgLYGQL-GWFKRPGPREREAALRCLEqvsMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:cd03263   81 PQFDALFDEL--TVREHLR--FYARLkGLPKSEIKEEVELLLRVLG---LTDKANKRARTLSGGMKRKLSLAIALIGGPS 153
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLE 212
Cdd:cd03263  154 VLLLDEPTSGLDPASRRAIWDLILEVRK-GRSIILTTHSMD 193
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
19-246 1.09e-38

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 134.74  E-value: 1.09e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-------AQARKRIGY 91
Cdd:COG1126    2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLtdskkdiNKLRRKVGM 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFP-TSVLDVVMMGLYGQLGWfkrpgPRE--REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:COG1126   82 VFQQFNL---FPhLTVLENVTLAPIKVKKM-----SKAeaEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAM 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 DADLYFMDEPFAGVD--AVTEeaILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFT-PENlK 244
Cdd:COG1126  154 EPKVMLFDEPTSALDpeLVGE--VLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMdGGRIVEEGPPEEFFEnPQH-E 230

                 ..
gi 917519534 245 RT 246
Cdd:COG1126  231 RT 232
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
19-212 2.22e-38

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 134.60  E-value: 2.22e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAqarkriGYVPQ 94
Cdd:COG4525    4 LTVRHVSVRYpgggQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVT------GPGAD 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSV---DWDFP-TSVLDVVMMGLYgqlgwFKRPGPREREA-ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:COG4525   78 RGVVfqkDALLPwLNVLDNVAFGLR-----LRGVPKAERRArAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAAD 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:COG4525  153 PRFLLMDEPFGALDALTREQMQELLLDVwQRTGKGVFLITHSVE 196
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
21-212 5.18e-38

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 132.35  E-value: 5.18e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   21 VRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA---------RKRIGY 91
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLnskkaskfrREKLGY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   92 VPQR-GSVDWDfptSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:TIGR03608  81 LFQNfALIENE---TVEENLDLGLKYK----KLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPP 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 917519534  171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:TIGR03608 154 PLILADEPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPE 195
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
19-248 8.37e-38

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 133.04  E-value: 8.37e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRekpaLWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPvASGQVRFFGQSLAQ------ARKRiGYV 92
Cdd:COG4138    1 LQLNDVAVAGR----LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDwsaaelARHR-AYL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSvdwdfPTSVLDVvmmGLYGQLGWFKRPGPREREAALRCL-EQVSMQAFTTRQISQLSGGQQQRVFLARALAQ--- 168
Cdd:COG4138   75 SQQQS-----PPFAMPV---FQYLALHQPAGASSEAVEQLLAQLaEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwp 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 ----DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE-TVRdYFDHLTLL-NVQVIASGPMEEVFTPEN 242
Cdd:COG4138  147 tinpEGQLLLLDEPMNSLDVAQQAALDRLLRELCQQGITVVMSSHDLNhTLR-HADRVWLLkQGKLVASGETAEVMTPEN 225

                 ....*.
gi 917519534 243 LKRTYG 248
Cdd:COG4138  226 LSEVFG 231
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
19-243 1.12e-37

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 135.27  E-value: 1.12e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----AQARkRIGYVP 93
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLftnlpPRER-RVGFVF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QrgsvDWD-FP-TSVLDVVMMGLYGqlgwfKRPGPREREA-ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:COG1118   82 Q----HYAlFPhMTVAENIAFGLRV-----RPPSKAEIRArVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEP 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 171 DLYFMDEPFAGVDA-VTEE--AILRVLHElkKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT-PENL 243
Cdd:COG1118  153 EVLLLDEPFGALDAkVRKElrRWLRRLHD--ELGGTTVFVTHDQEEALELADRVVVMNQgRIEQVGTPDEVYDrPATP 228
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
19-237 1.35e-37

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 131.92  E-value: 1.35e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAV---LGLVPVA--SGQVRFFGQ-------SLAQAR 86
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlNDLIPGApdEGEVLLDGKdiydldvDVLELR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSVdwdFPTSVLDVVMMGLYGQLgwfKRPGPREREAALRCLEQVSMQAFTTRQIS--QLSGGQQQRVFLAR 164
Cdd:cd03260   81 RRVGMVFQKPNP---FPGSIYDNVAYGLRLHG---IKLKEELDERVEEALRKAALWDEVKDRLHalGLSGGQQQRLCLAR 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 165 ALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVR---DY--FdhltLLNVQVIASGPMEEV 237
Cdd:cd03260  155 ALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAArvaDRtaF----LLNGRLVEFGPTEQI 227
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
19-215 1.71e-37

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 129.64  E-value: 1.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGY 91
Cdd:cd03246    1 LEVENVSFRYpgAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWdpnelGDHVGY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRgsvDWDFPTSVLDVVmmglygqlgwfkrpgprereaalrcleqvsmqafttrqisqLSGGQQQRVFLARALAQDAD 171
Cdd:cd03246   81 LPQD---DELFSGSIAENI-----------------------------------------LSGGQRQRLGLARALYGNPR 116
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:cd03246  117 ILVLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPETLA 160
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
19-225 2.48e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 130.39  E-value: 2.48e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGqLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL----AQARKRIGYVPQ 94
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVlkqpQKLRRRIGYLPQ 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPTS-VLDvvmmglYgqLGWFKR-PGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:cd03264   80 EFGVYPNFTVReFLD------Y--IAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSI 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03264  152 LIVDEPTAGLDPEERIRFRNLLSELGE-DRIVILSTHIVEDVESLCNQVAVLN 203
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
19-220 4.79e-37

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 129.96  E-value: 4.79e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-------AQARKRIGY 91
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLtddkkniNELRQKVGM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFP-TSVLDVVMMGLYGQLGWFKRpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:cd03262   81 VFQQFNL---FPhLTVLENITLAPIKVKGMSKA---EAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNP 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDH 220
Cdd:cd03262  155 KVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADR 204
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
20-225 7.54e-37

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 129.30  E-value: 7.54e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKP-ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--RKRIGYVPQrg 96
Cdd:cd03226    1 RIENISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKerRKSIGYVMQ-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 SVDWDFPT-SVLDVVMMGLygqlgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFM 175
Cdd:cd03226   79 DVDYQLFTdSVREELLLGL--------KELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIF 150
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 176 DEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03226  151 DEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLA 200
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
19-237 9.86e-37

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 129.57  E-value: 9.86e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL------AQARKRIGYV 92
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDItklpphERARAGIAYV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   93 PQ-RGSvdwdFPT-SVLDVVMMGLYGqLGWFKRPGPREREAALRCLEQvsmqaFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:TIGR03410  81 PQgREI----FPRlTVEENLLTGLAA-LPRRSRKIPDEIYELFPVLKE-----MLGRRGGDLSGGQQQQLAIARALVTRP 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534  171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:TIGR03410 151 KLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGmAILLVEQYLDFARELADRYYVMeRGRVVASGAGDEL 219
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
21-244 2.09e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 128.64  E-value: 2.09e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL----AQARKRIGYVPQRG 96
Cdd:cd03265    3 VENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVvrepREVRRRIGIVFQDL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 SVDwDFPTSVLDVVMMG-LYGQlgwfkrPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFM 175
Cdd:cd03265   83 SVD-DELTGWENLYIHArLYGV------PGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFL 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 176 DEPFAGVDAVTEEAILRVLHELKK-QGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGpmeevfTPENLK 244
Cdd:cd03265  156 DEPTIGLDPQTRAHVWEYIEKLKEeFGMTILLTTHYMEEAEQLCDRVAIIDHgRIIAEG------TPEELK 220
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
19-248 2.31e-36

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 129.88  E-value: 2.31e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYR-----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQA 85
Cdd:TIGR04521   1 IKLKNVSYIYQpgtpfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRditakkkkKLKDL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   86 RKRIGYVPQrgsvdwdFP------TSVLDVVMMGLygqlgwfKRPGPREREA---ALRCLEQVSM-QAFTTRQISQLSGG 155
Cdd:TIGR04521  81 RKKVGLVFQ-------FPehqlfeETVYKDIAFGP-------KNLGLSEEEAeerVKEALELVGLdEEYLERSPFELSGG 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  156 QQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGP 233
Cdd:TIGR04521 147 QMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLhKEKGLTVILVTHSMEDVAEYADRVIVMHKgKIVLDGT 226
                         250
                  ....*....|....*
gi 917519534  234 MEEVFTPENLKRTYG 248
Cdd:TIGR04521 227 PREVFSDVDELEKIG 241
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
19-225 5.08e-36

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 126.95  E-value: 5.08e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS---LAQARKRIGyvpqr 95
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSyqkNIEALRRIG----- 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 gsvdwdfptSVLDVvmMGLYG------QLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:cd03268   76 ---------ALIEA--PGFYPnltareNLRLLARLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGN 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN 225
Cdd:cd03268  145 PDLLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIIN 200
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
19-239 1.41e-35

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 129.43  E-value: 1.41e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA--------QAR 86
Cdd:COG1135    2 IELENLSKTFPTKggpvTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTalserelrAAR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQ-------RgsvdwdfptSVLDVVMMGLYgQLGWFKRpgprEREA-ALRCLEQVSMQAFTTRQISQLSGGQQQ 158
Cdd:COG1135   82 RKIGMIFQhfnllssR---------TVAENVALPLE-IAGVPKA----EIRKrVAELLELVGLSDKADAYPSQLSGGQKQ 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEE 236
Cdd:COG1135  148 RVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDInRELGLTIVLITHEMDVVRRICDRVAVLeNGRIVEQGPVLD 227

                 ...
gi 917519534 237 VFT 239
Cdd:COG1135  228 VFA 230
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
19-247 2.55e-35

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 126.12  E-value: 2.55e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKlpmhkrARLGIGYL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDvvmmGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:cd03218   81 PQEASIFRKL--TVEE----NILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKF 154
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDletVRDYF---DHLTLLNV-QVIASGPMEEVFTPENLKRTY 247
Cdd:cd03218  155 LLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHN---VRETLsitDRAYIIYEgKVLAEGTPEEIAANELVRKVY 230
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
19-242 8.71e-35

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 124.48  E-value: 8.71e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDvdLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQAR--KRigyvP--- 93
Cdd:COG3840    2 LRLDDLTYRYGDFPLRFD--LTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPpaER----Pvsm 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 --QRGSVdwdFP-TSVLDVVMMGLYGQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:COG3840   76 lfQENNL---FPhLTVAQNIGLGLRPGL----KLTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKR 148
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPEN 242
Cdd:COG3840  149 PILLLDEPFSALDPALRQEMLDLVDELcRERGLTVLMVTHDPEDAARIADRVLLVaDGRIAADGPTAALLDGEP 222
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
19-238 9.10e-35

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 125.90  E-value: 9.10e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGY 91
Cdd:PRK13635   6 IRVEHISFRYPDaaTYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEEtvwdvRRQVGM 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQrgSVDWDF-PTSVLDVVMMGLYGQlgwfkrpG-PRE------REAalrcLEQVSMQAFTTRQISQLSGGQQQRVFLA 163
Cdd:PRK13635  86 VFQ--NPDNQFvGATVQDDVAFGLENI-------GvPREemvervDQA----LRQVGMEDFLNREPHRLSGGQKQRVAIA 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 164 RALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVRDYfDHLTLLNV-QVIASGPMEEVF 238
Cdd:PRK13635 153 GVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAAQA-DRVIVMNKgEILEEGTPEEIF 228
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
19-237 1.29e-34

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 129.75  E-value: 1.29e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKR-IGYV 92
Cdd:COG1129    5 LEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEpvrfrSPRDAQAAgIAII 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMG-LYGQLGWFKRpgPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:COG1129   85 HQELNL---VPNlSVAENIFLGrEPRRGGLIDW--RAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDA 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 171 DLYFMDEPFAgvdAVTE---EAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:COG1129  160 RVLILDEPTA---SLTErevERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLrDGRLVGTGPVAEL 227
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
19-246 2.72e-34

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 123.99  E-value: 2.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAV---LGLVPVA--SGQVRFFGQ-------SLAQAR 86
Cdd:COG1117   12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmNDLIPGArvEGEILLDGEdiydpdvDVVELR 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSVdwdFPTSVLDVVMMGLygqlgwfKRPGPRER----EAALRCLEQV----------SMQAFTtrqisqL 152
Cdd:COG1117   92 RRVGMVFQKPNP---FPKSIYDNVAYGL-------RLHGIKSKseldEIVEESLRKAalwdevkdrlKKSALG------L 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLET---VRDY--FdhltLLNVQ 227
Cdd:COG1117  156 SGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVIVTHNMQQaarVSDYtaF----FYLGE 230
                        250       260
                 ....*....|....*....|
gi 917519534 228 VIASGPMEEVFT-PENlKRT 246
Cdd:COG1117  231 LVEFGPTEQIFTnPKD-KRT 249
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
19-250 4.56e-34

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 123.56  E-value: 4.56e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIGYVP 93
Cdd:PRK10253   8 LRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHyaskeVARRIGLLA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRGSVDWDFptSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLY 173
Cdd:PRK10253  88 QNATTPGDI--TVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIM 165
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 174 FMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHL-TLLNVQVIASGPMEEVFTPENLKRTYGER 250
Cdd:PRK10253 166 LLDEPTTWLDISHQIDLLELLSELnREKGYTLAAVLHDLNQACRYASHLiALREGKIVAQGAPKEIVTAELIERIYGLR 244
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
20-238 5.40e-34

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 122.33  E-value: 5.40e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREK-PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGYVP 93
Cdd:cd03254    4 EFENVNFSYDEKkPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIdirdiSRKSLRSMIGVVL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRgsvDWDFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQVSMQAFTTR-------QISQ----LSGGQQQRVFL 162
Cdd:cd03254   84 QD---TFLFSGTIMENIRLG---------RPNATD-EEVIEAAKEAGAHDFIMKlpngydtVLGEnggnLSQGERQLLAI 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVF 238
Cdd:cd03254  151 ARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMK-GRTSIIIAHRLSTIKNADKILVLDDGKIIEEGTHDELL 225
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
19-244 6.27e-34

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 123.31  E-value: 6.27e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA------QARKRIG 90
Cdd:TIGR04520   1 IEVENVSFSYPesEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLdeenlwEIRKKVG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   91 YVPQRgsvdwdfP------TSVLDVVMMGLYGQlgwfkrpG-PRE--REAALRCLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:TIGR04520  81 MVFQN-------PdnqfvgATVEDDVAFGLENL-------GvPREemRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVA 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKK-QGKTVVVVHHDLETVRDYfDHLTLLNV-QVIASGPMEEVFT 239
Cdd:TIGR04520 147 IAGVLAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKeEGITVISITHDMEEAVLA-DRVIVMNKgKIVAEGTPREIFS 225

                  ....*.
gi 917519534  240 -PENLK 244
Cdd:TIGR04520 226 qVELLK 231
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
19-224 6.62e-34

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 120.23  E-value: 6.62e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQArkrigyvpqrgsv 98
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFA------------- 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 dwdfptsvldvvmmglygqlgwfkrpGPREREAALrcleqVSMqafttrqISQLSGGQQQRVFLARALAQDADLYFMDEP 178
Cdd:cd03216   68 --------------------------SPRDARRAG-----IAM-------VYQLSVGERQMVEIARALARNARLLILDEP 109
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 179 FAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:cd03216  110 TAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVL 155
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
19-253 6.95e-34

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 122.45  E-value: 6.95e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:COG1137    4 LEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHlpmhkrARLGIGYL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDVVMMGLygQLGWFKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG1137   84 PQEASIFRKL--TVEDNILAVL--ELRKLSKKEREERLEEL--LEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKF 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 173 YFMDEPFAGVD--AVTEeaILRVLHELKKQGKTVVVVHHDletVRDYF---DHLTLLNV-QVIASGPMEEVFTPENLKRT 246
Cdd:COG1137  158 ILLDEPFAGVDpiAVAD--IQKIIRHLKERGIGVLITDHN---VRETLgicDRAYIISEgKVLAEGTPEEILNNPLVRKV 232

                 ....*...
gi 917519534 247 Y-GERMRW 253
Cdd:COG1137  233 YlGEDFRL 240
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
19-255 7.53e-34

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 122.89  E-value: 7.53e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQR-GS 97
Cdd:PRK11248   2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGVVFQNeGL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 VDWdfpTSVLDVVMMGLygQLGWFKRPgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:PRK11248  82 LPW---RNVQDNVAFGL--QLAGVEKM--QRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDE 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 178 PFAGVDAVTEEA----ILRVLHElkkQGKTVVVVHHDLETVRDYFDHLTLLnvqviASGPMEEVftpENLKRTYGERMRW 253
Cdd:PRK11248 155 PFGALDAFTREQmqtlLLKLWQE---TGKQVLLITHDIEEAVFMATELVLL-----SPGPGRVV---ERLPLNFARRFVA 223

                 ..
gi 917519534 254 GE 255
Cdd:PRK11248 224 GE 225
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
19-246 1.29e-33

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 121.68  E-value: 1.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKR-IGYVPQR 95
Cdd:cd03296    3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDvpVQERnVGFVFQH 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03296   83 YAL---FRhMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLL 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 175 MDEPFAGVDA-VTEE--AILRVLHElkKQGKTVVVVHHDLETVRDYFDHLTLLNvqviaSGPMEEVFTPENLKRT 246
Cdd:cd03296  160 LDEPFGALDAkVRKElrRWLRRLHD--ELHVTTVFVTHDQEEALEVADRVVVMN-----KGRIEQVGTPDEVYDH 227
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
32-215 3.04e-33

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 121.60  E-value: 3.04e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA---------RKRIGYV-------PQR 95
Cdd:cd03294   38 VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMsrkelrelrRKKISMVfqsfallPHR 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 gsvdwdfptSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFM 175
Cdd:cd03294  118 ---------TVLENVAFGLEVQ----GVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLM 184
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 917519534 176 DEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDL-ETVR 215
Cdd:cd03294  185 DEAFSALDPLIRREMQDELLRLqAELQKTIVFITHDLdEALR 226
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
19-246 4.21e-33

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 120.48  E-value: 4.21e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAV---LGLVPVA--SGQVRFFGQS-------LAQAR 86
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLnrmNDLVPGVriEGKVLFDGQDiydkkidVVELR 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   87 KRIGYVPQRGSvdwDFPTSVLDVVMMGLygqlgwfKRPGPRER----EAALRCLEQVSMQAFTTRQISQ----LSGGQQQ 158
Cdd:TIGR00972  82 RRVGMVFQKPN---PFPMSIYDNIAYGP-------RLHGIKDKkeldEIVEESLKKAALWDEVKDRLHDsalgLSGGQQQ 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVRDYFDHLTL-LNVQVIASGPMEEV 237
Cdd:TIGR00972 152 RLCIARALAVEPEVLLLDEPTSALDPIATGKIEELIQELKKK-YTIVIVTHNMQQAARISDRTAFfYDGELVEYGPTEQI 230

                  ....*....
gi 917519534  238 FTPENLKRT 246
Cdd:TIGR00972 231 FTNPKEKRT 239
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
19-210 5.20e-33

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 122.87  E-value: 5.20e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKR-IGYVPQr 95
Cdd:COG3839    4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDlpPKDRnIAMVFQ- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 gsvDWD-FPT-SVLDVVMMGLygqlgWFKRPGPREREAALR-CLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:COG3839   83 ---SYAlYPHmTVYENIAFPL-----KLRKVPKAEIDRRVReAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKV 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 173 YFMDEPFAGVDAVteeaiLRV--------LHelKKQGKTVVVVHHD 210
Cdd:COG3839  155 FLLDEPLSNLDAK-----LRVemraeikrLH--RRLGTTTIYVTHD 193
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
36-239 8.09e-33

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 122.52  E-value: 8.09e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARK---------RIGYVPQRGSVdwdFPT-S 105
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARgiflpphrrRIGYVFQEARL---FPHlS 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VLDVVmmgLYGQlgwfKRPGPREREAAL-RCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDA 184
Cdd:COG4148   94 VRGNL---LYGR----KRAPRAERRISFdEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDL 166
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 185 VTEEAILRVLHELKKQGKT-VVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFT 239
Cdd:COG4148  167 ARKAEILPYLERLRDELDIpILYVSHSLDEVARLADHVVLLeQGRVVASGPLAEVLS 223
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
19-248 1.32e-32

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 119.27  E-value: 1.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPalwdVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPvASGQVRFFGQSLAQ------ARKRiGYV 92
Cdd:PRK03695   1 MQLNDVAVSTRLGP----LSAEVRAGEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAwsaaelARHR-AYL 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSvdwdfPTSVLDVV-MMGLYGQLGwfkrPGPREREAALRCL-EQVSMQAFTTRQISQLSGGQQQRVFLARALAQ-- 168
Cdd:PRK03695  75 SQQQT-----PPFAMPVFqYLTLHQPDK----TRTEAVASALNEVaEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvw 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 -----DADLYFMDEPFAGVDaVTEEAIL-RVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPE 241
Cdd:PRK03695 146 pdinpAGQLLLLDEPMNSLD-VAQQAALdRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQgKLLASGRRDEVLTPE 224

                 ....*..
gi 917519534 242 NLKRTYG 248
Cdd:PRK03695 225 NLAQVFG 231
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
32-217 1.32e-32

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 118.50  E-value: 1.32e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQARKRIGYVPQrgsvdwDF- 102
Cdd:TIGR02673  16 AALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEdvnrlrgrQLPLLRRRIGVVFQ------DFr 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  103 --PT-SVLDVVMMGLYGQlGWFKRPGPREREAALRcleQVSM--QAFTTRQisQLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:TIGR02673  90 llPDrTVYENVALPLEVR-GKKEREIQRRVGAALR---QVGLehKADAFPE--QLSGGEQQRVAIARAIVNSPPLLLADE 163
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 917519534  178 PFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:TIGR02673 164 PTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRV 203
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
19-239 2.38e-32

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 120.54  E-value: 2.38e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSLAQAR----- 86
Cdd:COG0444    2 LEVRNLKVYFPTRrgvvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSekelr 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 ----KRIGYVPQrgsvdwDfPTSVLDVVMMgLYGQLG---WFKRPGPRE--REAALRCLEQVSMQAfTTRQIS----QLS 153
Cdd:COG0444   82 kirgREIQMIFQ------D-PMTSLNPVMT-VGDQIAeplRIHGGLSKAeaRERAIELLERVGLPD-PERRLDryphELS 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 154 GGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHltlLNV----QV 228
Cdd:COG0444  153 GGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADR---VAVmyagRI 229
                        250
                 ....*....|.
gi 917519534 229 IASGPMEEVFT 239
Cdd:COG0444  230 VEEGPVEELFE 240
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
19-212 8.49e-32

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 116.76  E-value: 8.49e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDL--TVVYREKP--ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------AR-- 86
Cdd:COG4181    9 IELRGLtkTVGTGAGEltILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFAldedarARlr 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 -KRIGYVPQrgsvdwDF---PT-SVLDVVMMGLygQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:COG4181   89 aRHVGFVFQ------SFqllPTlTALENVMLPL--EL----AGRRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVA 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKK-QGKTVVVVHHDLE 212
Cdd:COG4181  157 LARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNReRGTTLVLVTHDPA 208
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
19-243 1.06e-31

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 116.56  E-value: 1.06e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGYV 92
Cdd:cd03253    1 IEFENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQdirevTLDSLRRAIGVV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgsvdwdfpTSVL--DVVMMGL-YGqlgwfkRPGPRE---REAALR-CLEQVSM---QAFTT----RQIsQLSGGQQQ 158
Cdd:cd03253   81 PQ---------DTVLfnDTIGYNIrYG------RPDATDeevIEAAKAaQIHDKIMrfpDGYDTivgeRGL-KLSGGEKQ 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVF 238
Cdd:cd03253  145 RVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSK-GRTTIVIAHRLSTIVNADKIIVLKDGRIVERGTHEELL 223

                 ....*
gi 917519534 239 TPENL 243
Cdd:cd03253  224 AKGGL 228
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
19-227 2.21e-31

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 115.27  E-value: 2.21e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG-LVPV--ASGQVRFFGQSLAQ---ARKRIGYV 92
Cdd:COG4136    2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtLSPAfsASGEVLLNGRRLTAlpaEQRRIGIL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRgsvDWDFP-TSVLDVVMMGLYGQLGwfkrpGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:COG4136   82 FQD---DLLFPhLSVGENLAFALPPTIG-----RAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPR 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 172 LYFMDEPFAGVDAVTEEAILR-VLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQ 227
Cdd:COG4136  154 ALLLDEPFSKLDAALRAQFREfVFEQIRQRGIPALLVTHDEEDAPAAGRVLDLGNWQ 210
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
19-252 2.25e-31

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 115.83  E-value: 2.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA------QARKRIGYV 92
Cdd:TIGR04406   2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDIThlpmheRARLGIGYL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   93 PQRGSVdwdF-PTSVLDVVMMGLYGQlgwfKRPGPREREAALRCL-EQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:TIGR04406  82 PQEASI---FrKLTVEENIMAVLEIR----KDLDRAEREERLEALlEEFQISHLRDNKAMSLSGGERRRVEIARALATNP 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENLKRTY-G 248
Cdd:TIGR04406 155 KFILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDgKVLAEGTPAEIVANEKVRRVYlG 234

                  ....
gi 917519534  249 ERMR 252
Cdd:TIGR04406 235 EQFR 238
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
19-238 2.40e-31

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 121.39  E-value: 2.40e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR-----IGY 91
Cdd:COG4618  331 LSVENLTVVPpgSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREelgrhIGY 410
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQrgsvdwD---FPTSVLDVVMMglygqlgwFKRPGPREREAALR---CLEqvsM-----QAFTTRqI----SQLSGGQ 156
Cdd:COG4618  411 LPQ------DvelFDGTIAENIAR--------FGDADPEKVVAAAKlagVHE---MilrlpDGYDTR-IgeggARLSGGQ 472
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHD---LETVrdyfDHLTLL-NVQVIASG 232
Cdd:COG4618  473 RQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRpslLAAV----DKLLVLrDGRVQAFG 548

                 ....*.
gi 917519534 233 PMEEVF 238
Cdd:COG4618  549 PRDEVL 554
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
19-212 2.45e-31

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 119.05  E-value: 2.45e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKP------------------------ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQ 74
Cdd:COG4175    4 IEVRNLYKIFGKRPeralklldqgkskdeilektgqtvGVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  75 VRFFGQSLAQA---------RKRIGYV-------PQRgsvdwdfptSVLDVVMMGL--YGQlgwfkrpGPREREA-ALRC 135
Cdd:COG4175   84 VLIDGEDITKLskkelrelrRKKMSMVfqhfallPHR---------TVLENVAFGLeiQGV-------PKAERRErAREA 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 136 LEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVteeaILRVLH-EL----KKQGKTVVVVHHD 210
Cdd:COG4175  148 LELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPL----IRREMQdELlelqAKLKKTIVFITHD 223

                 ..
gi 917519534 211 LE 212
Cdd:COG4175  224 LD 225
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
19-245 4.13e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 116.33  E-value: 4.13e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-------SLAQARKRIG 90
Cdd:PRK13639   2 LETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEpikydkkSLLEVRKTVG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRGSvDWDFPTSVLDVVMMGLYgQLGWFKRP-GPREREAalrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:PRK13639  82 IVFQNPD-DQLFAPTVEEDVAFGPL-NLGLSKEEvEKRVKEA----LKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMK 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKR 245
Cdd:PRK13639 156 PEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMsDGKIIKEGTPKEVFSDIETIR 232
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
19-242 5.48e-31

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 114.74  E-value: 5.48e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKpALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ---SLAQARKRIGYVPQR 95
Cdd:cd03299    1 LKVENLSKDWKEF-KLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKditNLPPEKRDISYVPQN 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03299   80 YAL---FPhMTVYKNIAYGLKKR----KVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILL 152
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHL-TLLNVQVIASGPMEEVF-TPEN 242
Cdd:cd03299  153 LDEPFSALDVRTKEKLREELKKIRKEfGVTVLHVTHDFEEAWALADKVaIMLNGKLIQVGKPEEVFkKPKN 223
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
6-211 7.45e-31

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 119.77  E-value: 7.45e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    6 KTVQHPESGASSP----LRVRDLTVVY-REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ 80
Cdd:TIGR02868 318 AEGSAPAAGAVGLgkptLELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGV 397
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   81 SLAQA-----RKRIGYVPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQV-----------SMQAF 144
Cdd:TIGR02868 398 PVSSLdqdevRRRVSVCAQDAHL---FDTTVRENLRLA---------RPDATD-EELWAALERVgladwlralpdGLDTV 464
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534  145 TTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHElKKQGKTVVVVHHDL 211
Cdd:TIGR02868 465 LGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLA-ALSGRTVVLITHHL 530
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
34-250 7.74e-31

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 117.11  E-value: 7.74e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKR-IGYVPQRGSVdwdFP-TSVLDV 109
Cdd:PRK10851  18 LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRlhARDRkVGFVFQHYAL---FRhMTVFDN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 110 VMMGLyGQLGWFKRPGPRE-REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEE 188
Cdd:PRK10851  95 IAFGL-TVLPRRERPNAAAiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRK 173
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 189 AILRVLHELKKQGK-TVVVVHHDLETVRDYFDHltllnVQVIASGPMEEVFTPENLKRTYGER 250
Cdd:PRK10851 174 ELRRWLRQLHEELKfTSVFVTHDQEEAMEVADR-----VVVMSQGNIEQAGTPDQVWREPATR 231
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
19-243 1.43e-30

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 113.49  E-value: 1.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ---ARKRIGYVPQR 95
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNlppHKRPVNTVFQN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03300   81 YAL---FPhLTVFENIAFGLRLK----KLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLL 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLE---TVRDYfdhltllnVQVIASGPMEEVFTPENL 243
Cdd:cd03300  154 LDEPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQEealTMSDR--------IAVMNKGKIQQIGTPEEI 218
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
31-245 1.62e-30

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 116.49  E-value: 1.62e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   31 KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ---------ARKRIGYVPQRGSVdwd 101
Cdd:TIGR01186   6 KKGVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKqspvelrevRRKKIGMVFQQFAL--- 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  102 FP-TSVLDVVMMGLyGQLGWfkrPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFA 180
Cdd:TIGR01186  83 FPhMTILQNTSLGP-ELLGW---PEQERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFS 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534  181 GVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNvqviaSGPMEEVFTPENLKR 245
Cdd:TIGR01186 159 ALDPLIRDSMQDELKKLqATLQKTIVFITHDLDEAIRIGDRIVIMK-----AGEIVQVGTPDEILR 219
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
9-251 1.88e-30

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 114.11  E-value: 1.88e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   9 QHPESGASspLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ---- 84
Cdd:PRK10575   4 YTNHSDTT--FALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwssk 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 --ARKrIGYVPQRgsvdwdFPT----SVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQ 158
Cdd:PRK10575  82 afARK-VAYLPQQ------LPAaegmTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQ 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEE 236
Cdd:PRK10575 155 RAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGgEMIAQGTPAE 234
                        250
                 ....*....|....*
gi 917519534 237 VFTPENLKRTYGERM 251
Cdd:PRK10575 235 LMRGETLEQIYGIPM 249
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
19-224 2.47e-30

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 113.95  E-value: 2.47e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLV---PVASGQVRFFGQSLAQA---------- 85
Cdd:PRK09984   5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVQREgrlardirks 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RKRIGYVPQRGSVDWDFptSVLDVVMMGLYGQ-------LGWFKrpgPREREAALRCLEQVSMQAFTTRQISQLSGGQQQ 158
Cdd:PRK09984  85 RANTGYIFQQFNLVNRL--SVLENVLIGALGStpfwrtcFSWFT---REQKQRALQALTRVGMVHFAHQRVSTLSGGQQQ 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:PRK09984 160 RVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVAL 226
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
19-216 5.48e-30

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 112.32  E-value: 5.48e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGY 91
Cdd:cd03251    1 VEFKNVTFRYPgdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHdvrdyTLASLRRQIGL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQrgsvdwD---FPTSVLDVVMMGlygqlgwfkRPGPrEREAALRCLEQVSMQAFTTR-------QI----SQLSGGQQ 157
Cdd:cd03251   81 VSQ------DvflFNDTVAENIAYG---------RPGA-TREEVEEAARAANAHEFIMElpegydtVIgergVKLSGGQR 144
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 158 QRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRD 216
Cdd:cd03251  145 QRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMK-NRTTFVIAHRLSTIEN 202
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
19-212 9.20e-30

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 116.27  E-value: 9.20e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVvyreKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQA-RKRIGYV 92
Cdd:COG1129  257 LEVEGLSV----GGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKpvrirSPRDAiRAGIAYV 332
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgsvdwD------FPT-SVLDVVMMGLYGQLGWFKR-PGPREREAALRCLEQVSMQAFTTRQ-ISQLSGGQQQRVFLA 163
Cdd:COG1129  333 PE------DrkgeglVLDlSIRENITLASLDRLSRGGLlDRRRERALAEEYIKRLRIKTPSPEQpVGNLSGGNQQKVVLA 406
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 164 RALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:COG1129  407 KWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELP 455
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
16-237 1.20e-29

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 111.74  E-value: 1.20e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  16 SSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslAQARKRIGYVPQR 95
Cdd:PRK09544   2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIK------RNGKLRIGYVPQK 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVDWDFPTSVLDVVMMglygqlgwfkRPGPReREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFM 175
Cdd:PRK09544  76 LYLDTTLPLTVNRFLRL----------RPGTK-KEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVL 144
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 176 DEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEV 237
Cdd:PRK09544 145 DEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVV 207
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
19-252 2.82e-29

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 110.37  E-value: 2.82e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL------AQARKRIGYV 92
Cdd:PRK10895   4 LTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDIsllplhARARRGIGYL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDVVMMGLYGQLGWFKRpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:PRK10895  84 PQEASIFRRL--SVYDNLMAVLQIRDDLSAE---QREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKF 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENLKRTY-GER 250
Cdd:PRK10895 159 ILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQgHLIAHGTPTEILQDEHVKRVYlGED 238

                 ..
gi 917519534 251 MR 252
Cdd:PRK10895 239 FR 240
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
28-214 4.02e-29

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 110.11  E-value: 4.02e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG----QSLAQARKRIGYV-PQRGSVDWDF 102
Cdd:cd03267   31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGlvpwKRRKKFLRRIGVVfGQKTQLWWDL 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 PtsvldvVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGV 182
Cdd:cd03267  111 P------VIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGL 184
                        170       180       190
                 ....*....|....*....|....*....|...
gi 917519534 183 DAVTEEAILRVLHEL-KKQGKTVVVVHHDLETV 214
Cdd:cd03267  185 DVVAQENIRNFLKEYnRERGTTVLLTSHYMKDI 217
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
14-241 5.34e-29

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 111.44  E-value: 5.34e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  14 GASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRI 89
Cdd:PRK13537   3 MSVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPsrarHARQRV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQRGSVDWDFpTSVLDVVMMGLYgqlgwFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:PRK13537  83 GVVPQFDNLDPDF-TVRENLLVFGRY-----FGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVND 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPE 241
Cdd:PRK13537 157 PDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIeEGRKIAEGAPHALIESE 229
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
18-210 5.72e-29

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 110.15  E-value: 5.72e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGS 97
Cdd:PRK11247  12 PLLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREDTRLMFQDAR 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 -VDWdfpTSVLDVVMMGLYGQlgWfkrpgpreREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:PRK11247  92 lLPW---KKVIDNVGLGLKGQ--W--------RDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 917519534 177 EPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHD 210
Cdd:PRK11247 159 EPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHD 193
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
10-232 7.09e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 109.87  E-value: 7.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  10 HPESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKA---VLGLVPV--ASGQVRFFGQSL-- 82
Cdd:PRK14243   2 STLNGTETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrLNDLIPGfrVEGKVTFHGKNLya 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  83 -----AQARKRIGYVPQRGSvdwDFPTSVLDVV-----MMGLYGQLGwfkrpgprerEAALRCLEQVSMQAFTTRQISQ- 151
Cdd:PRK14243  82 pdvdpVEVRRRIGMVFQKPN---PFPKSIYDNIaygarINGYKGDMD----------ELVERSLRQAALWDEVKDKLKQs 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 152 ---LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVRDYFDHLTLLNVQV 228
Cdd:PRK14243 149 glsLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQ-YTIIIVTHNMQQAARVSDMTAFFNVEL 227

                 ....
gi 917519534 229 IASG 232
Cdd:PRK14243 228 TEGG 231
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
32-217 9.42e-29

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 108.26  E-value: 9.42e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR-IGYVPQR-GSVDWDF---PT-S 105
Cdd:cd03292   15 AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRaIPYLRRKiGVVFQDFrllPDrN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VLDVVMMGLygQLGWFKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAV 185
Cdd:cd03292   95 VYENVAFAL--EVTGVPPREIRKRVPAA--LELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD 170
                        170       180       190
                 ....*....|....*....|....*....|..
gi 917519534 186 TEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:cd03292  171 TTWEIMNLLKKINKAGTTVVVATHAKELVDTT 202
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
21-252 1.24e-28

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 109.47  E-value: 1.24e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS--------LAQARKRIGYV 92
Cdd:PRK11831  10 MRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENipamsrsrLYTVRKRMSML 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptSVLDVVMMGL--YGQLgwfkrPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:PRK11831  90 FQSGALFTDM--NVFDNVAYPLreHTQL-----PAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEP 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNVQ-VIASGpmeevfTPENLKRTYG 248
Cdd:PRK11831 163 DLIMFDEPFVGQDPITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKkIVAHG------SAQALQANPD 236

                 ....
gi 917519534 249 ERMR 252
Cdd:PRK11831 237 PRVR 240
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
36-212 1.49e-28

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 107.77  E-value: 1.49e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPaGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARK---------RIGYVPQRGSVdwdFPTsv 106
Cdd:cd03297   16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKkinlppqqrKIGLVFQQYAL---FPH-- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 107 LDVVMMGLYGQLgwFKRPGP-REREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAV 185
Cdd:cd03297   90 LNVRENLAFGLK--RKRNREdRISVDEL--LDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRA 165
                        170       180
                 ....*....|....*....|....*...
gi 917519534 186 TEEAILRVLHELKKQ-GKTVVVVHHDLE 212
Cdd:cd03297  166 LRLQLLPELKQIKKNlNIPVIFVTHDLS 193
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
19-239 1.59e-28

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 113.81  E-value: 1.59e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIGY 91
Cdd:TIGR03375 464 IEFRNVSFAYpgQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQidpadLRRNIGY 543
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   92 VPQRGSVdwdFPTSVLDVVMMGlygqlgwfkRPGPRErEAALRCLEQVSMQAFTTR-------QISQ----LSGGQQQRV 160
Cdd:TIGR03375 544 VPQDPRL---FYGTLRDNIALG---------APYADD-EEILRAAELAGVTEFVRRhpdgldmQIGErgrsLSGGQRQAV 610
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  161 FLARALAQDADLYFMDEPFAGVDAVTEEailRVLHELKK--QGKTVVVVHHDLeTVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:TIGR03375 611 ALARALLRDPPILLLDEPTSAMDNRSEE---RFKDRLKRwlAGKTLVLVTHRT-SLLDLVDRIIVMdNGRIVADGPKDQV 686

                  ..
gi 917519534  238 FT 239
Cdd:TIGR03375 687 LE 688
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
21-232 2.71e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 108.67  E-value: 2.71e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYVPQ 94
Cdd:PRK13647   7 VEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAEnekwvRSKVGLVFQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSvDWDFPTSVLDVVMMGLYgQLGWFKRPGPREREAALRCleqVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:PRK13647  87 DPD-DQVFSSTVWDDVAFGPV-NMGLDKDEVERRVEEALKA---VRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIV 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASG 232
Cdd:PRK13647 162 LDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEgRVLAEG 220
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
19-232 4.59e-28

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 105.47  E-value: 4.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA----RKRIGYV 92
Cdd:cd03247    1 LSINNVSFSYpeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLekalSSLISVL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPTSvldvvmmgLYGQLGwfkrpgprereaalrcleqvsmqafttrqiSQLSGGQQQRVFLARALAQDADL 172
Cdd:cd03247   81 NQRPYL---FDTT--------LRNNLG------------------------------RRFSGGERQRLALARILLQDAPI 119
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVrDYFDHLTLL-NVQVIASG 232
Cdd:cd03247  120 VLLDEPTVGLDPITERQLLSLIFEVLK-DKTLIWITHHLTGI-EHMDKILFLeNGKIIMQG 178
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
19-214 5.56e-28

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 105.21  E-value: 5.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVvyreKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKR-IGYV 92
Cdd:cd03215    5 LEVRGLSV----KGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKpvtrrSPRDAIRAgIAYV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgsvdwdfptsvlDVVMMGLYGQLgwfkrpgPREREAALRCLeqvsmqafttrqisqLSGGQQQRVFLARALAQDADL 172
Cdd:cd03215   81 PE-------------DRKREGLVLDL-------SVAENIALSSL---------------LSGGNQQKVVLARWLARDPRV 125
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETV 214
Cdd:cd03215  126 LILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDEL 167
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
2-242 1.08e-27

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 111.07  E-value: 1.08e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   2 ITQPKTVQHPESGASSP----LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLikavLGLVP----VA 71
Cdd:PRK11160 318 TEQKPEVTFPTTSTAAAdqvsLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTL----LQLLTrawdPQ 393
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  72 SGQVRFFGQSL-----AQARKRIGYVPQRGSVdwdFPTSVLDVVMMGLygqlgwfkrpgPREREAALR-CLEQVSMQAFT 145
Cdd:PRK11160 394 QGEILLNGQPIadyseAALRQAISVVSQRVHL---FSATLRDNLLLAA-----------PNASDEALIeVLQQVGLEKLL 459
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 146 T-------------RQisqLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLe 212
Cdd:PRK11160 460 EddkglnawlgeggRQ---LSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEH-AQNKTVLMITHRL- 534
                        250       260       270
                 ....*....|....*....|....*....|.
gi 917519534 213 TVRDYFDHLTLL-NVQVIASGPMEEVFTPEN 242
Cdd:PRK11160 535 TGLEQFDRICVMdNGQIIEQGTHQELLAQQG 565
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
11-232 2.00e-27

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 107.99  E-value: 2.00e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  11 PESGASSPLRVrDLTVV---YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--- 84
Cdd:PRK13536  32 SIPGSMSTVAI-DLAGVsksYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPArar 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 -ARKRIGYVPQRGSVDWDFpTSVLDVVMMGLYGQLGwfkrpgPREREAAL-RCLEQVSMQAFTTRQISQLSGGQQQRVFL 162
Cdd:PRK13536 111 lARARIGVVPQFDNLDLEF-TVRENLLVFGRYFGMS------TREIEAVIpSLLEFARLESKADARVSDLSGGMKRRLTL 183
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQV-IASG 232
Cdd:PRK13536 184 ARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRkIAEG 254
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
19-224 2.16e-27

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 104.76  E-value: 2.16e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKP----ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG----QSLAQARKRIG 90
Cdd:cd03266    2 ITADALTKRFRDVKktvqAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGfdvvKEPAEARRRLG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVP-QRGSVDWdfpTSVLDvvMMGLYGQLGWFKRpgpREREAALRCL-EQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:cd03266   82 FVSdSTGLYDR---LTARE--NLEYFAGLYGLKG---DELTARLEELaDRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:cd03266  154 DPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVL 209
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
15-238 2.36e-27

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 105.82  E-value: 2.36e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAV-----------------LGLVPVASGQVRF 77
Cdd:PRK10619   2 SENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCInflekpsegsivvngqtINLVRDKDGQLKV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  78 FGQS-LAQARKRIGYVPQRGSVdWDFPTsVLDVVMMGLYGQLGWFKRPGpreREAALRCLEQVSM-QAFTTRQISQLSGG 155
Cdd:PRK10619  82 ADKNqLRLLRTRLTMVFQHFNL-WSHMT-VLENVMEAPIQVLGLSKQEA---RERAVKYLAKVGIdERAQGKYPVHLSGG 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 156 QQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVI-ASGPM 234
Cdd:PRK10619 157 QQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIeEEGAP 236

                 ....
gi 917519534 235 EEVF 238
Cdd:PRK10619 237 EQLF 240
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
32-216 2.49e-27

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 104.82  E-value: 2.49e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF---FGQ-SLAQA---------RKRIGYVPQrgsv 98
Cdd:COG4778   25 PVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhdGGWvDLAQAspreilalrRRTIGYVSQ---- 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 dwdF----P-TSVLDVVMMGLYgQLGWfKRPGPRER-EAALRCLE------QVSMQAFttrqisqlSGGQQQRVFLARAL 166
Cdd:COG4778  101 ---FlrviPrVSALDVVAEPLL-ERGV-DREEARARaRELLARLNlperlwDLPPATF--------SGGEQQRVNIARGF 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLEtVRD 216
Cdd:COG4778  168 IADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEE-VRE 216
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
21-242 4.32e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 105.46  E-value: 4.32e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG-----QSLAQARKRIGYVP 93
Cdd:PRK13632  10 VENVSFSYPnsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGitiskENLKEIRKKIGIIF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QrgSVDWDF-PTSVLDVVMMGLYGqlgwfKRPGPREREAALRCL-EQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK13632  90 Q--NPDNQFiGATVEDDIAFGLEN-----KKVPPKKMKDIIDDLaKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPE 162
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQG-KTVVVVHHDLETV--RDYFdhLTLLNVQVIASGPMEEVFTPEN 242
Cdd:PRK13632 163 IIIFDESTSMLDPKGKREIKKIMVDLRKTRkKTLISITHDMDEAilADKV--IVFSEGKLIAQGKPKEILNNKE 234
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
21-210 8.01e-27

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 108.23  E-value: 8.01e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFfgqslaQARKRIGYVPQrgSVDW 100
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI------PKGLRIGYLPQ--EPPL 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 DFPTSVLDVVMMGLygqlgwfkrpgpREREAALRCLEQVSMQAFTT---------------------------------- 146
Cdd:COG0488   73 DDDLTVLDTVLDGD------------AELRALEAELEELEAKLAEPdedlerlaelqeefealggweaearaeeilsglg 140
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 147 -------RQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAvteEAILRVLHELKKQGKTVVVVHHD 210
Cdd:COG0488  141 fpeedldRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDL---ESIEWLEEFLKNYPGTVLVVSHD 208
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
19-242 1.36e-26

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 103.77  E-value: 1.36e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKA---VLGLVPVA--SGQVRFFGQSL-------AQAR 86
Cdd:PRK14267   5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTfnrLLELNEEArvEGEVRLFGRNIyspdvdpIEVR 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSvdwDFP-TSVLDVVMMGL-YGQLGWFKRPGPREREAALR---CLEQVSMQafTTRQISQLSGGQQQRVF 161
Cdd:PRK14267  85 REVGMVFQYPN---PFPhLTIYDNVAIGVkLNGLVKSKKELDERVEWALKkaaLWDEVKDR--LNDYPSNLSGGQRQRLV 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR--DYFDHLTLlnVQVIASGPMEEVF- 238
Cdd:PRK14267 160 IARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARvsDYVAFLYL--GKLIEVGPTRKVFe 237

                 ....
gi 917519534 239 TPEN 242
Cdd:PRK14267 238 NPEH 241
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
19-243 2.11e-26

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 107.03  E-value: 2.11e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----AQARKR-IGYV 92
Cdd:COG3845    6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVrirspRDAIALgIGMV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVdwdFPT-SVLDVVMMGLYGQLGWFKRPGpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:COG3845   86 HQHFML---VPNlTVAENIVLGLEPTKGGRLDRK-AARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGAR 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 172 LYFMDEPfagvDAV-----TEEaILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVfTPENL 243
Cdd:COG3845  162 ILILDEP----TAVltpqeADE-LFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLrRGKVVGTVDTAET-SEEEL 233
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
19-232 3.57e-26

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 101.42  E-value: 3.57e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPalWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ---ARKRIGYVPQR 95
Cdd:cd03298    1 VRLDKIRFSYGEQP--MHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAappADRPVSMLFQE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYGQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:cd03298   79 NNL---FAhLTVEQNVGLGLSPGL----KLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLL 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASG 232
Cdd:cd03298  152 LDEPFAALDPALRAEMLDLVLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLdNGRIAAQG 211
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
36-237 4.56e-26

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 104.42  E-value: 4.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARK---------RIGYVPQRGSVdwdFPTsv 106
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKgiflppekrRIGYVFQEARL---FPH-- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  107 LDVVMMGLYGQlgWFKRPGPREREAAlRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVT 186
Cdd:TIGR02142  90 LSVRGNLRYGM--KRARPSERRISFE-RVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPR 166
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 917519534  187 EEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:TIGR02142 167 KYEILPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLeDGRVAAAGPIAEV 219
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
19-210 7.63e-26

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 100.79  E-value: 7.63e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA--QARKR-IGYVPQR 95
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTdlPPKDRdIAMVFQN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLygQLGWFKRPGPRER--EAAlrclEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:cd03301   81 YAL---YPhMTVYDNIAFGL--KLRKVPKDEIDERvrEVA----ELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKV 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 917519534 173 YFMDEPFAGVDA---VTEEAILRVLHelKKQGKTVVVVHHD 210
Cdd:cd03301  152 FLMDEPLSNLDAklrVQMRAELKRLQ--QRLGTTTIYVTHD 190
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
19-212 1.18e-25

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 104.72  E-value: 1.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVV-YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----AQARKR-IGY 91
Cdd:COG3845  258 LEVENLSVRdDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDItglspRERRRLgVAY 337
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQ----RGSVDwDFptSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQvsMQAFTTR------QISQLSGGQQQRVF 161
Cdd:COG3845  338 IPEdrlgRGLVP-DM--SVAENLILGRYRRPPFSRGGFLDRKAIRAFAEEL--IEEFDVRtpgpdtPARSLSGGNQQKVI 412
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:COG3845  413 LARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLD 463
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
30-209 1.33e-25

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 100.36  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIGYVPQRGSVdwdFPT 104
Cdd:cd03245   16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQldpadLRRNIGYVPQDVTL---FYG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 105 SVLDVVMMGLygqlgwfkrpGPREREAALRCLEQVSMQAFTTR-------QIS----QLSGGQQQRVFLARALAQDADLY 173
Cdd:cd03245   93 TLRDNITLGA----------PLADDERILRAAELAGVTDFVNKhpngldlQIGergrGLSGGQRQAVALARALLNDPPIL 162
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 917519534 174 FMDEPFAGVDAVTEEailRVLHELKK--QGKTVVVVHH 209
Cdd:cd03245  163 LLDEPTSAMDMNSEE---RLKERLRQllGDKTLIIITH 197
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
12-242 1.76e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 100.89  E-value: 1.76e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  12 ESGASSP--LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPV------ASGQVRFFGQSLA 83
Cdd:PRK14246   2 EAGKSAEdvFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIydskikVDGKVLYFGKDIF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 QA-----RKRIGYVPQRGSvdwDFPtsvldvvMMGLYGQLGW-FKRPGPREREAALRCLEQVSMQAFTTRQI-------- 149
Cdd:PRK14246  82 QIdaiklRKEVGMVFQQPN---PFP-------HLSIYDNIAYpLKSHGIKEKREIKKIVEECLRKVGLWKEVydrlnspa 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 150 SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVRDYFDHLTLL-NVQV 228
Cdd:PRK14246 152 SQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLyNGEL 230
                        250
                 ....*....|....*
gi 917519534 229 IASGPMEEVFT-PEN 242
Cdd:PRK14246 231 VEWGSSNEIFTsPKN 245
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
19-224 2.05e-25

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 99.16  E-value: 2.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPA------LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVA--SGQVRFFGQSLAQA--RKR 88
Cdd:cd03213    4 LSFRNLTVTVKSSPSksgkqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLgvSGEVLINGRPLDKRsfRKI 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVdwdFPTsvLDVvmmglygqlgwfkrpgpreREAalrcleqVSMQAfttrQISQLSGGQQQRVFLARALAQ 168
Cdd:cd03213   84 IGYVPQDDIL---HPT--LTV-------------------RET-------LMFAA----KLRGLSGGERKRVSIALELVS 128
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDL-ETVRDYFDHLTLL 224
Cdd:cd03213  129 NPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPsSEIFELFDKLLLL 185
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
33-245 3.00e-25

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 102.04  E-value: 3.00e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ---SLAQARKRIGYVPQRGSVdwdFPT-SVLD 108
Cdd:TIGR03265  19 ALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRditRLPPQKRDYGIVFQSYAL---FPNlTVAD 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  109 VVMMGLYGQLGwfKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEE 188
Cdd:TIGR03265  96 NIAYGLKNRGM--GRAEVAERVAEL--LDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEPLSALDARVRE 171
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534  189 AILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNVQVIasgpmEEVFTPENLKR 245
Cdd:TIGR03265 172 HLRTEIRQLQRRlGVTTIMVTHDQEEALSMADRIVVMNHGVI-----EQVGTPQEIYR 224
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
19-217 3.22e-25

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 99.11  E-value: 3.22e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIGY 91
Cdd:cd03244    3 IEFKNVSLRYRPnlPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKiglhdLRSRISI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQ-----RGSVdwdfpTSVLDvvmmglygqlgwfkrpgPRER---EAALRCLEQVSMQAFTTRQI-----------SQL 152
Cdd:cd03244   83 IPQdpvlfSGTI-----RSNLD-----------------PFGEysdEELWQALERVGLKEFVESLPggldtvveeggENL 140
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDY 217
Cdd:cd03244  141 SVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIREAFK-DCTVLTIAHRLDTIIDS 204
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
34-212 3.49e-25

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 99.50  E-value: 3.49e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ----AR-----KRIGYVPQRGSVDWDFpT 104
Cdd:PRK11629  25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKlssaAKaelrnQKLGFIYQFHHLLPDF-T 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 105 SVLDVVMMGLYGQlgwfKRPGpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDA 184
Cdd:PRK11629 104 ALENVAMPLLIGK----KKPA-EINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPTGNLDA 178
                        170       180
                 ....*....|....*....|....*....
gi 917519534 185 VTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:PRK11629 179 RNADSIFQLLGELnRLQGTAFLVVTHDLQ 207
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
3-236 3.55e-25

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 103.77  E-value: 3.55e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   3 TQPKTVQHPESGASSPLRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVaSGQVRFFGQ- 80
Cdd:PRK11174 334 HPQQGEKELASNDPVTIEAEDLEILSPDgKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY-QGSLKINGIe 412
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  81 ----SLAQARKRIGYVPQRGSVdwdFPTSVLDVVMMGlygqlgwfkrpGPREREAALR-CLEQVSMQAFTTR-------- 147
Cdd:PRK11174 413 lrelDPESWRKHLSWVGQNPQL---PHGTLRDNVLLG-----------NPDASDEQLQqALENAWVSEFLPLlpqgldtp 478
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 148 ---QISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:PRK11174 479 igdQAAGLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQALNAA-SRRQTTLMVTHQLEDLAQWDQIWVMQ 557
                        250
                 ....*....|..
gi 917519534 225 NVQVIASGPMEE 236
Cdd:PRK11174 558 DGQIVQQGDYAE 569
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
36-225 1.08e-24

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 98.11  E-value: 1.08e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSL--AQARKRIGYVPQRgsvdwDFPTSVLDV- 109
Cdd:cd03234   25 DVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRkpDQFQKCVAYVRQD-----DILLPGLTVr 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 110 ------VMMglygQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:cd03234  100 etltytAIL----RLPRKSSDAIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLD 175
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 184 AVTEEAILRVLHELKKQGKTVVV-VHHDLETVRDYFDHLTLLN 225
Cdd:cd03234  176 SFTALNLVSTLSQLARRNRIVILtIHQPRSDLFRLFDRILLLS 218
hmuV PRK13547
heme ABC transporter ATP-binding protein;
19-252 1.09e-24

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 99.13  E-value: 1.09e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP--------VASGQVRFFGQSLAQ------ 84
Cdd:PRK13547   2 LTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTgggaprgaRVTGDVTLNGEPLAAidaprl 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 ARKRiGYVPQRGSVdwDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLAR 164
Cdd:PRK13547  82 ARLR-AVLPQAAQP--AFAFSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFAR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 165 ALAQ---------DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKT-VVVVHHDLETVRDYFDHLTLL-NVQVIASGP 233
Cdd:PRK13547 159 VLAQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLgVLAIVHDPNLAARHADRIAMLaDGAIVAHGA 238
                        250
                 ....*....|....*....
gi 917519534 234 MEEVFTPENLKRTYGERMR 252
Cdd:PRK13547 239 PADVLTPAHIARCYGFAVR 257
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
32-216 1.31e-24

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 98.24  E-value: 1.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-------QARKRIGYVPQRGSVdwdFP- 103
Cdd:PRK09493  15 QVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpkvderLIRQEAGMVFQQFYL---FPh 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 104 TSVLDVVMMGLYGQLGWFKRPGpreREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:PRK09493  92 LTALENVMFGPLRVRGASKEEA---EKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALD 168
                        170       180       190
                 ....*....|....*....|....*....|...
gi 917519534 184 AVTEEAILRVLHELKKQGKTVVVVHHDLETVRD 216
Cdd:PRK09493 169 PELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEK 201
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
18-210 1.55e-24

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 101.63  E-value: 1.55e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP-------VASGQVRFFGQSLAQARKRIG 90
Cdd:PRK10938 260 RIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPqgysndlTLFGRRRGSGETIWDIKKHIG 339
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTTRQ-ISQLSGGQQQRVFLARALAQD 169
Cdd:PRK10938 340 YVSSSLHLDYRVSTSVRNVILSGFFDSIGIYQAVSDRQQKLAQQWLDILGIDKRTADApFHSLSWGQQRLALIVRALVKH 419
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKT--VVVVHHD 210
Cdd:PRK10938 420 PTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETqlLFVSHHA 462
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
20-239 1.69e-24

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 99.88  E-value: 1.69e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVY----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQARK 87
Cdd:PRK11153   3 ELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQdltalsekELRKARR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  88 RIGYVPQ-------RgsvdwdfptSVLDVVMMGLygQLGWFKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRV 160
Cdd:PRK11153  83 QIGMIFQhfnllssR---------TVFDNVALPL--ELAGTPKAEIKARVTEL--LELVGLSDKADRYPAQLSGGQKQRV 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVF 238
Cdd:PRK11153 150 AIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIdAGRLVEQGTVSEVF 229

                 .
gi 917519534 239 T 239
Cdd:PRK11153 230 S 230
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
19-217 1.71e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 99.39  E-value: 1.71e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK-----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG-------------- 79
Cdd:PRK13651   3 IKVKNIVKIFNKKlptelKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFkdeknkkktkekek 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  80 ---------------QSLAQARKRIGYVPQRGSVDWdFPTSVLDVVMMGlygqlgwfkrP---GPREREAALRCLEQVSM 141
Cdd:PRK13651  83 vleklviqktrfkkiKKIKEIRRRVGVVFQFAEYQL-FEQTIEKDIIFG----------PvsmGVSKEEAKKRAAKYIEL 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 142 ----QAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:PRK13651 152 vgldESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEW 231
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
3-223 2.08e-24

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 101.42  E-value: 2.08e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   3 TQPKTVQHPESGASSPLRVRDLTVV-YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFfgqs 81
Cdd:COG4178  347 ALPEAASRIETSEDGALALEDLTLRtPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR---- 422
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  82 laQARKRIGYVPQR-----GSVDwdfptSVLdvvmmgLYgqlgwfkrPGPRER---EAALRCLEQVSMQAFTTR------ 147
Cdd:COG4178  423 --PAGARVLFLPQRpylplGTLR-----EAL------LY--------PATAEAfsdAELREALEAVGLGHLAERldeead 481
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 148 --QIsqLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHdlETVRDYFDH-LTL 223
Cdd:COG4178  482 wdQV--LSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREELPGTTVISVGHR--STLAAFHDRvLEL 556
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
19-246 2.19e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 98.19  E-value: 2.19e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS-----GQVRFFGQSLAQARKRIGYVP 93
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIYERRVNLNRLR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRGSVDWD----FPTSVLDVVMMGLyGQLGWfkRPGPREREAALRCLEQVSMQAFTTRQISQ----LSGGQQQRVFLARA 165
Cdd:PRK14258  88 RQVSMVHPkpnlFPMSVYDNVAYGV-KIVGW--RPKLEIDDIVESALKDADLWDEIKHKIHKsaldLSGGQQQRLCIARA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVRDYFDHLTLLN------VQVIASGPMEEVF 238
Cdd:PRK14258 165 LAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHNLHQVSRLSDFTAFFKgnenriGQLVEFGLTKKIF 244

                 ....*...
gi 917519534 239 TPENLKRT 246
Cdd:PRK14258 245 NSPHDSRT 252
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
5-238 2.77e-24

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 99.91  E-value: 2.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   5 PKTVQHPESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ 84
Cdd:PRK11607   6 PRPQAKTRKALTPLLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSH 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 A---RKRIGYVPQRGSVdwdFP-TSVLDVVMMGLygqlgwfKRPGPREREAALRC---LEQVSMQAFTTRQISQLSGGQQ 157
Cdd:PRK11607  86 VppyQRPINMMFQSYAL---FPhMTVEQNIAFGL-------KQDKLPKAEIASRVnemLGLVHMQEFAKRKPHQLSGGQR 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 158 QRVFLARALAQDADLYFMDEPFAGVDAVTEEAI-LRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLN----VQViasG 232
Cdd:PRK11607 156 QRVALARSLAKRPKLLLLDEPMGALDKKLRDRMqLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNrgkfVQI---G 232

                 ....*.
gi 917519534 233 PMEEVF 238
Cdd:PRK11607 233 EPEEIY 238
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
19-239 2.92e-24

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 101.27  E-value: 2.92e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQAR-----KRIGY 91
Cdd:TIGR01842 317 LSVENVTIVPpgGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDretfgKHIGY 396
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   92 VPQRGSVdwdFPTSVL-DVVMMGlygqlgwfKRPGPREREAALRcLEQVSM------QAFTTrQI----SQLSGGQQQRV 160
Cdd:TIGR01842 397 LPQDVEL---FPGTVAeNIARFG--------ENADPEKIIEAAK-LAGVHElilrlpDGYDT-VIgpggATLSGGQRQRI 463
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHH--DLETVRDYFdhLTLLNVQVIASGPMEEVF 238
Cdd:TIGR01842 464 ALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKARGITVVVITHrpSLLGCVDKI--LVLQDGRIARFGERDEVL 541

                  .
gi 917519534  239 T 239
Cdd:TIGR01842 542 A 542
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
30-244 4.94e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 97.78  E-value: 4.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRfFGQSLAQA----------RKRIGYVPQrgsvd 99
Cdd:PRK13634  19 ERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVT-IGERVITAgkknkklkplRKKVGIVFQ----- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 100 wdFPTSVL-------DVVmmglYGQLGWfkrpGPREREAALRCLEQVSM----QAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:PRK13634  93 --FPEHQLfeetvekDIC----FGPMNF----GVSEEDAKQKAREMIELvglpEELLARSPFELSGGQMRRVAIAGVLAM 162
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFT-PENLK 244
Cdd:PRK13634 163 EPEVLVLDEPTAGLDPKGRKEMMEMFYKLhKEKGLTTVLVTHSMEDAARYADQIVVMhKGTVFLQGTPREIFAdPDELE 241
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
18-216 7.49e-24

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 99.89  E-value: 7.49e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYR--------EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ---SLAQA- 85
Cdd:COG5265  350 PLVVGGGEVRFEnvsfgydpERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQdirDVTQAs 429
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 -RKRIGYVPQrgsvdwdfptsvlDVVMMG-------LYGqlgwfkRPG--PREREAALRcLEQVSmqAFttrqISQ---- 151
Cdd:COG5265  430 lRAAIGIVPQ-------------DTVLFNdtiayniAYG------RPDasEEEVEAAAR-AAQIH--DF----IESlpdg 483
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 152 -----------LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRD 216
Cdd:COG5265  484 ydtrvgerglkLSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREV-ARGRTTLVIAHRLSTIVD 558
cbiO PRK13643
energy-coupling factor transporter ATPase;
33-238 7.77e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 97.11  E-value: 7.77e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF--FGQSLAQARKRIGYVPQRGSVDWDFPTSVL--D 108
Cdd:PRK13643  21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgdIVVSSTSKQKEIKPVRKKVGVVFQFPESQLfeE 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 109 VVMMGL-YGQLGWFKRPGPREREAALRcLEQVSM-QAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVT 186
Cdd:PRK13643 101 TVLKDVaFGPQNFGIPKEKAEKIAAEK-LEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKA 179
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 187 EEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVF 238
Cdd:PRK13643 180 RIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKgHIISCGTPSDVF 232
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
19-215 7.95e-24

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 96.24  E-value: 7.95e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKaVLGLVPVA-SGQVRFFGQSL-----------AQAR 86
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLR-VLNLLETPdSGQLNIAGHQFdfsqkpsekaiRLLR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSVdWDFPTsVLDVVMMGLYGQLGWFKRpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:COG4161   82 QKVGMVFQQYNL-WPHLT-VMENLIEAPCKVLGLSKE---QAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARAL 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:COG4161  157 MMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFAR 205
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
19-214 8.00e-24

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 95.12  E-value: 8.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQAR----KRIGYVPQ 94
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRdephENILYLGH 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   95 RGSVDWDFptSVLDvvmmglygQLGWFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:TIGR01189  81 LPGLKPEL--SALE--------NLHFWAAIHGGAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWI 150
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 917519534  175 MDEPFAGVDAVTEEAILRVLHE-LKKQGKTVVVVHHDLETV 214
Cdd:TIGR01189 151 LDEPTTALDKAGVALLAGLLRAhLARGGIVLLTTHQDLGLV 191
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
19-239 8.78e-24

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 99.76  E-value: 8.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP----VASGQVRFFGQSLAQA----- 85
Cdd:COG4172    7 LSVEDLSVAFGqgggTVEAVKGVSFDIAAGETLALVGESGSGKSVTALSILRLLPdpaaHPSGSILFDGQDLLGLserel 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RK----RIGYVPQRgsvdwdfPTSVLDVVM---------MGLYGQLGwfkrpGPREREAALRCLEQVSMQAFTTRQIS-- 150
Cdd:COG4172   87 RRirgnRIAMIFQE-------PMTSLNPLHtigkqiaevLRLHRGLS-----GAAARARALELLERVGIPDPERRLDAyp 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 151 -QLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLL-NVQ 227
Cdd:COG4172  155 hQLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRElGMALLLITHDLGVVRRFADRVAVMrQGE 234
                        250
                 ....*....|..
gi 917519534 228 VIASGPMEEVFT 239
Cdd:COG4172  235 IVEQGPTAELFA 246
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
19-251 8.97e-24

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 96.84  E-value: 8.97e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-------SLAQARKRIG 90
Cdd:PRK13636   6 LKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpidysrkGLMKLRESVG 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQrgsvDWD---FPTSVLDVVMMGLYGqlgwFKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALA 167
Cdd:PRK13636  86 MVFQ----DPDnqlFSASVYQDVSFGAVN----LKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLV 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENLKR 245
Cdd:PRK13636 158 MEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEgRVILQGNPKEVFAEKEMLR 237

                 ....*.
gi 917519534 246 TYGERM 251
Cdd:PRK13636 238 KVNLRL 243
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
19-212 1.02e-23

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 96.00  E-value: 1.02e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAV--LG-LVP--VASGQVRFFGQSL-------AQAR 86
Cdd:PRK14239   6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNdLNPevTITGSIVYNGHNIysprtdtVDLR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSvdwDFPTSVLDVVMMGLygqlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQ--------LSGGQQQ 158
Cdd:PRK14239  86 KEIGMVFQQPN---PFPMSIYENVVYGL-------RLKGIKDKQVLDEAVEKSLKGASIWDEVKDrlhdsalgLSGGQQQ 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLE 212
Cdd:PRK14239 156 RVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQ 208
cbiO PRK13650
energy-coupling factor transporter ATPase;
21-243 1.67e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 95.95  E-value: 1.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVY---REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYV 92
Cdd:PRK13650   7 VKNLTFKYkedQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEEnvwdiRHKIGMV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrgSVDWDF-PTSVLDVVMMGLYGQLGWFKRPGPREREAalrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK13650  87 FQ--NPDNQFvGATVEDDVAFGLENKGIPHEEMKERVNEA----LELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPK 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLetvrdyfDHLTLLN-VQVIASGPMEEVFTPENL 243
Cdd:PRK13650 161 IIILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDL-------DEVALSDrVLVMKNGQVESTSTPREL 227
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
28-232 1.80e-23

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 94.52  E-value: 1.80e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslaqarkrigyvpQRGSVDWDF----- 102
Cdd:cd03220   32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT-----------------VRGRVSSLLglggg 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 --PT-SVLD-VVMMG-LYGqlgwFKRPGPREREAalRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:cd03220   95 fnPElTGREnIYLNGrLLG----LSRKEIDEKID--EIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDE 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 178 PFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDH-LTLLNVQVIASG 232
Cdd:cd03220  169 VLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRaLVLEKGKIRFDG 224
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
17-239 1.81e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 95.36  E-value: 1.81e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  17 SPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLV-----PVASGQVRFFGQS-----LAQAR 86
Cdd:PRK14247   2 NKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDifkmdVIELR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQrgsVDWDFPT-SVLDVVMMGLYgqlgwFKRPGPREREaalrcLEQVSMQAFTTRQI------------SQLS 153
Cdd:PRK14247  82 RRVQMVFQ---IPNPIPNlSIFENVALGLK-----LNRLVKSKKE-----LQERVRWALEKAQLwdevkdrldapaGKLS 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 154 GGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR--DYFDHltLLNVQVIAS 231
Cdd:PRK14247 149 GGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARisDYVAF--LYKGQIVEW 226

                 ....*...
gi 917519534 232 GPMEEVFT 239
Cdd:PRK14247 227 GPTREVFT 234
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
19-237 2.07e-23

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 93.75  E-value: 2.07e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGL--VPVASGQVRFFGQSLAQArkrigyvpqrg 96
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDL----------- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 svdwdfptSVLDVVMMGLYgqLGwFKRPgPRereaalrcLEQVSMQAFtTRQISQ-LSGGQQQRVFLARALAQDADLYFM 175
Cdd:cd03217   70 --------PPEERARLGIF--LA-FQYP-PE--------IPGVKNADF-LRYVNEgFSGGEKKRNEILQLLLLEPDLAIL 128
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 176 DEPFAGVDAVTEEAILRVLHELKKQGKTVVVV-HHD--LETVRDYFDHLtLLNVQVIASGPMEEV 237
Cdd:cd03217  129 DEPDSGLDIDALRLVAEVINKLREEGKSVLIItHYQrlLDYIKPDRVHV-LYDGRIVKSGDKELA 192
cbiO PRK13646
energy-coupling factor transporter ATPase;
19-243 3.20e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 95.62  E-value: 3.20e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR-----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG---------QSLAQ 84
Cdd:PRK13646   3 IRFDNVSYTYQkgtpyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDitithktkdKYIRP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 ARKRIGYVPQrgsvdwdFPTSVL---DVVMMGLYGQLGwFKRPGPREREAALRCLeqvsMQAFTTRQIS-----QLSGGQ 156
Cdd:PRK13646  83 VRKRIGMVFQ-------FPESQLfedTVEREIIFGPKN-FKMNLDEVKNYAHRLL----MDLGFSRDVMsqspfQMSGGQ 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK-KQGKTVVVVHHDLETVRDYFDhltllNVQVIASGPME 235
Cdd:PRK13646 151 MRKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYAD-----EVIVMKEGSIV 225

                 ....*...
gi 917519534 236 EVFTPENL 243
Cdd:PRK13646 226 SQTSPKEL 233
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
19-215 3.55e-23

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 94.31  E-value: 3.55e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKaVLGLVPVA-SGQVRFFGQ-----------SLAQAR 86
Cdd:PRK11124   3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLR-VLNLLEMPrSGTLNIAGNhfdfsktpsdkAIRELR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQRGSVdWDFPTsvldvVMMGLYGQ----LGWFKrpgPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFL 162
Cdd:PRK11124  82 RNVGMVFQQYNL-WPHLT-----VQQNLIEApcrvLGLSK---DQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAI 152
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:PRK11124 153 ARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVAR 205
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
28-237 4.94e-23

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 93.99  E-value: 4.94e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslaqarkrigyvpQRGSVdwdfpTSVL 107
Cdd:COG1134   36 REEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVE-----------------VNGRV-----SALL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 108 DvVMMGLYGQL-GwfkrpgpreRE-AALRCLeqvsMQAFTTRQISQL---------------------SGGQQQRVFLAR 164
Cdd:COG1134   94 E-LGAGFHPELtG---------REnIYLNGR----LLGLSRKEIDEKfdeivefaelgdfidqpvktySSGMRARLAFAV 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 165 ALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:COG1134  160 ATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLeKGRLVMDGDPEEV 233
cbiO PRK13641
energy-coupling factor transporter ATPase;
30-247 5.04e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 94.90  E-value: 5.04e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG---------QSLAQARKRIGYVPQRGSVDW 100
Cdd:PRK13641  19 EKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGyhitpetgnKNLKKLRKKVSLVFQFPEAQL 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 dFPTSVLDVVMmglYGQLGwFKRPGPREREAALRCLEQVSM-QAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:PRK13641  99 -FENTVLKDVE---FGPKN-FGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPA 173
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDH-LTLLNVQVIASGPMEEVFT-PENLKRTY 247
Cdd:PRK13641 174 AGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDvLVLEHGKLIKHASPKEIFSdKEWLKKHY 243
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
18-216 5.95e-23

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 97.06  E-value: 5.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRfFGQSLaqarkRIGYVPQ-RG 96
Cdd:COG0488  315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVK-LGETV-----KIGYFDQhQE 388
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 SVDWDfpTSVLDvvmmglygqlgWFKRPGPREREAALR-CLEqvSM-----QAFTtrQISQLSGGQQQRVFLARALAQDA 170
Cdd:COG0488  389 ELDPD--KTVLD-----------ELRDGAPGGTEQEVRgYLG--RFlfsgdDAFK--PVGVLSGGEKARLALAKLLLSPP 451
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKkqGkTVVVVHHD---LETVRD 216
Cdd:COG0488  452 NVLLLDEPTNHLDIETLEALEEALDDFP--G-TVLLVSHDryfLDRVAT 497
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
26-243 8.34e-23

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 93.32  E-value: 8.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  26 VVYREKP----ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYVPQRG 96
Cdd:cd03252    6 VRFRYKPdgpvILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALAdpawlRRQVGVVLQEN 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 SVdwdFPTSVLDVVMMGlygqlgwfkRPG-PRER-EAALR--------CLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:cd03252   86 VL---FNRSIRDNIALA---------DPGmSMERvIEAAKlagahdfiSELPEGYDTIVGEQGAGLSGGQRQRIAIARAL 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENL 243
Cdd:cd03252  154 IHNPRILIFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKNADRIIVMEKGRIVEQGSHDELLAENGL 229
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
28-212 9.25e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 94.77  E-value: 9.25e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG-LVPvASGQVRFFGQSLAQAR----KRIGYV-PQRGSVDWD 101
Cdd:COG4586   32 YREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGiLVP-TSGEVRVLGYVPFKRRkefaRRIGVVfGQRSQLWWD 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 102 FPtsVLDvvmmglygQLGWFKR----PGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:COG4586  111 LP--AID--------SFRLLKAiyriPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDE 180
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 917519534 178 PFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:COG4586  181 PTIGLDVVSKEAIREFLKEYnRERGTTILLTSHDMD 216
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
11-240 9.26e-23

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 92.48  E-value: 9.26e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  11 PESGAsspLRVRDLTVVYREK--PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS-----LA 83
Cdd:cd03369    2 PEHGE---IEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDistipLE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 QARKRIGYVPQRgsvdwdfPTsvldvVMMG-LYGQLGWFKRPGPREREAALRCLEQVsmqafttrqiSQLSGGQQQRVFL 162
Cdd:cd03369   79 DLRSSLTIIPQD-------PT-----LFSGtIRSNLDPFDEYSDEEIYGALRVSEGG----------LNLSQGQRQLLCL 136
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 163 ARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRDYfDhltllNVQVIASGPMEEVFTP 240
Cdd:cd03369  137 ARALLKRPRVLVLDEATASIDYATDALIQKTIREE-FTNSTILTIAHRLRTIIDY-D-----KILVMDAGEVKEYDHP 207
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
19-213 1.26e-22

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 91.86  E-value: 1.26e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG--QSLAQARKRIGYVPQRg 96
Cdd:PRK13539   3 LEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGgdIDDPDVAEACHYLGHR- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 svdwDFPTSVLDVV-----MMGLYGQlgwfkrpgprEREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:PRK13539  82 ----NAMKPALTVAenlefWAAFLGG----------EELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRP 147
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV-HHDLET 213
Cdd:PRK13539 148 IWILDEPTAALDAAAVALFAELIRAHLAQGGIVIAAtHIPLGL 190
NHLM_micro_ABC1 TIGR03796
NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes ...
19-236 1.72e-22

NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein; This protein describes a multidomain ABC transporter subunit that is one of three protein families associated with some regularity with a distinctive family of putative bacteriocins. It includes a bacteriocin-processing peptidase domain at the N-terminus. Model TIGR03793 describes a conserved propeptide region for this bacteriocin family, unusual because it shows obvious homology a region of the enzyme nitrile hydratase up to the classic Gly-Gly cleavage motif. This family is therefore predicted to be a subunit of a bacteriocin processing and export system characteristic to this system that we designate NHLM, Nitrile Hydratase Leader Microcin. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]


Pssm-ID: 274788 [Multi-domain]  Cd Length: 710  Bit Score: 96.17  E-value: 1.72e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRI-----GY 91
Cdd:TIGR03796 478 VELRNITFGYSplEPPLIENFSLTLQPGQRVALVGGSGSGKSTIAKLVAGLYQPWSGEILFDGIPREEIPREVlansvAM 557
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   92 VPQ-----RGSVD-----WDfPT-------------SVLDVVMmglygqlgwfKRPGPREREaalrcLEQVSMQafttrq 148
Cdd:TIGR03796 558 VDQdiflfEGTVRdnltlWD-PTipdadlvrackdaAIHDVIT----------SRPGGYDAE-----LAEGGAN------ 615
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  149 isqLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEeaiLRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQV 228
Cdd:TIGR03796 616 ---LSGGQRQRLEIARALVRNPSILILDEATSALDPETE---KIIDDNLRRRGCTCIIVAHRLSTIRDCDEIIVLERGKV 689

                  ....*...
gi 917519534  229 IASGPMEE 236
Cdd:TIGR03796 690 VQRGTHEE 697
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
20-216 1.92e-22

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 92.22  E-value: 1.92e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKP---ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGY 91
Cdd:cd03249    2 EFKNVSFRYPSRPdvpILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVdirdlNLRWLRSQIGL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFPTSVLDVVmmgLYGqlgwfkRPGPREREAalrclEQVSMQAFTTRQI---------------SQLSGGQ 156
Cdd:cd03249   82 VSQEPVL---FDGTIAENI---RYG------KPDATDEEV-----EEAAKKANIHDFImslpdgydtlvgergSQLSGGQ 144
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRD 216
Cdd:cd03249  145 KQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK-GRTTIVIAHRLSTIRN 203
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
19-249 2.28e-22

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 92.36  E-value: 2.28e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYVPQ 94
Cdd:PRK11300   6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEglpgHQIARMGVVRT 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPTSVLDVVMMGLYGQL------GWFKRPGPR--EREA---ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLA 163
Cdd:PRK11300  86 FQHVRLFREMTVIENLLVAQHQQLktglfsGLLKTPAFRraESEAldrAATWLERVGLLEHANRQAGNLAYGQQRRLEIA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 164 RALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPE 241
Cdd:PRK11300 166 RCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQgTPLANGTPEEIRNNP 245

                 ....*....
gi 917519534 242 NLKRTY-GE 249
Cdd:PRK11300 246 DVIKAYlGE 254
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
19-243 2.67e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 92.94  E-value: 2.67e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR-EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYV 92
Cdd:PRK13652   4 IETRDLCYSYSgSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKEnirevRKFVGLV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrGSVDWDFPTSVLDVVMMGLYgQLGWFKRPGPREREAALRCLeqvSMQAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:PRK13652  84 FQ-NPDDQIFSPTVEQDIAFGPI-NLGLDEETVAHRVSSALHML---GLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQV 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENL 243
Cdd:PRK13652 159 LVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKgRIVAYGTVEEIFLQPDL 231
cbiO PRK13640
energy-coupling factor transporter ATPase;
21-245 3.03e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 92.56  E-value: 3.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG-LVP--VASGQVRFFGQSLAQ-----ARKRIG 90
Cdd:PRK13640   8 FKHVSFTYPdsKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlLLPddNPNSKITVDGITLTAktvwdIREKVG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQrgSVDWDF-PTSVLDVVMMGLYgqlgwfKRPGPREREAAL--RCLEQVSMQAFTTRQISQLSGGQQQRVFLARALA 167
Cdd:PRK13640  88 IVFQ--NPDNQFvGATVGDDVAFGLE------NRAVPRPEMIKIvrDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFT-PENLKR 245
Cdd:PRK13640 160 VEPKIIILDESTSMLDPAGKEQILKLIRKLKKKnNLTVISITHDIDEANMADQVLVLDDGKLLAQGSPVEIFSkVEMLKE 239
cbiO PRK13649
energy-coupling factor transporter ATPase;
30-238 3.35e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 92.50  E-value: 3.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA---------QARKRIGYVPQrgsvdw 100
Cdd:PRK13649  19 EGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITstsknkdikQIRKKVGLVFQ------ 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 dFPTS------VLDVVMMGlygqlgwfkrP---GPREREAALRCLEQVSM----QAFTTRQISQLSGGQQQRVFLARALA 167
Cdd:PRK13649  93 -FPESqlfeetVLKDVAFG----------PqnfGVSQEEAEALAREKLALvgisESLFEKNPFELSGGQMRRVAIAGILA 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVF 238
Cdd:PRK13649 162 MEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKgKLVLSGKPKDIF 233
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
34-210 3.89e-22

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 95.18  E-value: 3.89e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQARKR-IGYVPQRGSVdWDFPT 104
Cdd:PRK10535  24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQdvatldadALAQLRREhFGFIFQRYHL-LSHLT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 105 SVLDVVMMGLYGQLGWFKRpgpREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDA 184
Cdd:PRK10535 103 AAQNVEVPAVYAGLERKQR---LLRAQEL--LQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDS 177
                        170       180
                 ....*....|....*....|....*.
gi 917519534 185 VTEEAILRVLHELKKQGKTVVVVHHD 210
Cdd:PRK10535 178 HSGEEVMAILHQLRDRGHTVIIVTHD 203
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
19-252 4.03e-22

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 94.89  E-value: 4.03e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS--GQVRFFGQSLAQA------RKRIG 90
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASnirdteRAGIV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   91 YVPQRGSVDWDFptSVLDVVMMGlygqlGWFKRPGPREREAA--LRC---LEQVSMQAF-TTRQISQLSGGQQQRVFLAR 164
Cdd:TIGR02633  82 IIHQELTLVPEL--SVAENIFLG-----NEITLPGGRMAYNAmyLRAknlLRELQLDADnVTRPVGDYGGGQQQLVEIAK 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  165 ALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENL 243
Cdd:TIGR02633 155 ALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIrDGQHVATKDMSTMSEDDII 234

                  ....*....
gi 917519534  244 KRTYGERMR 252
Cdd:TIGR02633 235 TMMVGREIT 243
PLN03232 PLN03232
ABC transporter C family member; Provisional
30-238 4.54e-22

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 95.43  E-value: 4.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASgqvrffgQSLAQARKRIGYVPQrgsVDWDFPTSVLDV 109
Cdd:PLN03232  629 SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAE-------TSSVVIRGSVAYVPQ---VSWIFNATVREN 698
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  110 VMMGlygqlgwfkrpGPREREAALRCLEQVSMQ----AFTTRQISQ-------LSGGQQQRVFLARALAQDADLYFMDEP 178
Cdd:PLN03232  699 ILFG-----------SDFESERYWRAIDVTALQhdldLLPGRDLTEigergvnISGGQKQRVSMARAVYSNSDIYIFDDP 767
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534  179 FAGVDAVTEEAILR--VLHELkkQGKTVVVVHHDLETVrDYFDHLTLLNVQVIA-SGPMEEVF 238
Cdd:PLN03232  768 LSALDAHVAHQVFDscMKDEL--KGKTRVLVTNQLHFL-PLMDRIILVSEGMIKeEGTFAELS 827
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
19-223 4.86e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 90.24  E-value: 4.86e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR-------IGY 91
Cdd:cd03231    1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSiargllyLGH 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdfpTSVLDvvmmglygQLGWFKRPGprEREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:cd03231   81 APGIKTT-----LSVLE--------NLRFWHADH--SDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRP 145
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 917519534 172 LYFMDEPFAGVDAVTEEAIL-RVLHELKKQGKTVVVVHHDLETVRDYFDHLTL 223
Cdd:cd03231  146 LWILDEPTTALDKAGVARFAeAMAGHCARGGMVVLTTHQDLGLSEAGARELDL 198
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
17-246 5.12e-22

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 91.35  E-value: 5.12e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  17 SPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF----------FGQS---LA 83
Cdd:PRK11264   2 SAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditidtarsLSQQkglIR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 QARKRIGYVPQRGSVdwdFP-TSVLDVVMMGLYgqlgwFKRPGPREREAAL--RCLEQVSMQAFTTRQISQLSGGQQQRV 160
Cdd:PRK11264  82 QLRQHVGFVFQNFNL---FPhRTVLENIIEGPV-----IVKGEPKEEATARarELLAKVGLAGKETSYPRRLSGGQQQRV 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIA-SGPMEEVFT 239
Cdd:PRK11264 154 AIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVeQGPAKALFA 233

                 ....*..
gi 917519534 240 PENLKRT 246
Cdd:PRK11264 234 DPQQPRT 240
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
4-239 5.73e-22

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 94.37  E-value: 5.73e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   4 QPKTVQHPESGASSP-LRVRDLTVVYREKPALW-----------DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPvA 71
Cdd:COG4172  260 EPRGDPRPVPPDAPPlLEARDLKVWFPIKRGLFrrtvghvkavdGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP-S 338
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  72 SGQVRFFGQSLAQA--------RKRIGYVPQR--GSVDwdfP-TSVLDVVMMGLYGQlgwFKRPGPREREA-ALRCLEQV 139
Cdd:COG4172  339 EGEIRFDGQDLDGLsrralrplRRRMQVVFQDpfGSLS---PrMTVGQIIAEGLRVH---GPGLSAAERRArVAEALEEV 412
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 140 SMQ-AFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDY 217
Cdd:COG4172  413 GLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLqREHGLAYLFISHDLAVVRAL 492
                        250       260
                 ....*....|....*....|...
gi 917519534 218 FDHLTLL-NVQVIASGPMEEVFT 239
Cdd:COG4172  493 AHRVMVMkDGKVVEQGPTEQVFD 515
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
49-243 6.52e-22

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 92.56  E-value: 6.52e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   49 IVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA---RKRIGYVPQRGSVdwdFP-TSVLDVVMMGLYGQLGWFKRP 124
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVpphLRHINMVFQSYAL---FPhMTVEENVAFGLKMRKVPRAEI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  125 GPREREAalrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEailRVLHELK----KQ 200
Cdd:TIGR01187  78 KPRVLEA----LRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRD---QMQLELKtiqeQL 150
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 917519534  201 GKTVVVVHHDLETVRDYFDHLTLLNvqviaSGPMEEVFTPENL 243
Cdd:TIGR01187 151 GITFVFVTHDQEEAMTMSDRIAIMR-----KGKIAQIGTPEEI 188
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
19-243 8.28e-22

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 93.09  E-value: 8.28e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKR-IGYVPQR 95
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHvpAENRhVNTVFQS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYGQlgwfKRPG----PREREAalrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:PRK09452  95 YAL---FPhMTVFENVAFGLRMQ----KTPAaeitPRVMEA----LRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNVQVIAS-GPMEEVF-TPENL 243
Cdd:PRK09452 164 KVLLLDESLSALDYKLRKQMQNELKALQRKlGITFVFVTHDQEEALTMSDRIVVMRDGRIEQdGTPREIYeEPKNL 239
cbiO PRK13637
energy-coupling factor transporter ATPase;
18-238 1.27e-21

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 91.26  E-value: 1.27e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYR-----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG-------QSLAQA 85
Cdd:PRK13637   2 SIKIENLTHIYMegtpfEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGvditdkkVKLSDI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RKRIGYVPQrgsvdwdFPTSVL-------DVVmmglYGQlgwfKRPGPREREAALRCLEQVSM-----QAFTTRQISQLS 153
Cdd:PRK13637  82 RKKVGLVFQ-------YPEYQLfeetiekDIA----FGP----INLGLSEEEIENRVKRAMNIvgldyEDYKDKSPFELS 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 154 GGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVRDYFDHLTLLNV-QVIAS 231
Cdd:PRK13637 147 GGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNmTIILVSHSMEDVAKLADRIIVMNKgKCELQ 226

                 ....*..
gi 917519534 232 GPMEEVF 238
Cdd:PRK13637 227 GTPREVF 233
PLN03130 PLN03130
ABC transporter C family member; Provisional
30-211 1.72e-21

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 93.65  E-value: 1.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG-LVPVASGQVRFfgqslaqaRKRIGYVPQrgsVDWDFPTSVLD 108
Cdd:PLN03130  629 ERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGeLPPRSDASVVI--------RGTVAYVPQ---VSWIFNATVRD 697
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  109 VVMMGLygqlgwfkrpgPREREAALRCLEQVSMQafttRQISQL---------------SGGQQQRVFLARALAQDADLY 173
Cdd:PLN03130  698 NILFGS-----------PFDPERYERAIDVTALQ----HDLDLLpggdlteigergvniSGGQKQRVSMARAVYSNSDVY 762
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 917519534  174 FMDEPFAGVDA-----VTEEAILRVLhelkkQGKTVVVVHHDL 211
Cdd:PLN03130  763 IFDDPLSALDAhvgrqVFDKCIKDEL-----RGKTRVLVTNQL 800
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
31-236 2.51e-21

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 92.72  E-value: 2.51e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  31 KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIkAVLGLV--PvASGQVRFFGQ-----SLAQARKRIGYVPQRGSVdwdFP 103
Cdd:PRK13657 348 RQGVEDVSFEAKPGQTVAIVGPTGAGKSTLI-NLLQRVfdP-QSGRILIDGTdirtvTRASLRRNIAVVFQDAGL---FN 422
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 104 TSVLDVVMMGlygqlgwfkRPGPREREAaLRCLEQVSMQAFTTRQI-----------SQLSGGQQQRVFLARALAQDADL 172
Cdd:PRK13657 423 RSIEDNIRVG---------RPDATDEEM-RAAAERAQAHDFIERKPdgydtvvgergRQLSGGERQRLAIARALLKDPPI 492
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKqGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEE 236
Cdd:PRK13657 493 LILDEATSALDVETEAKVKAALDELMK-GRTTFIIAHRLSTVRNADRILVFDNGRVVESGSFDE 555
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
33-238 2.93e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 89.81  E-value: 2.93e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF-----FGQSLAQARKRIGYVPQR------GS-VDW 100
Cdd:PRK13648  24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYnnqaiTDDNFEKLRKHIGIVFQNpdnqfvGSiVKY 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 DfptsvldvVMMGLYGQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFA 180
Cdd:PRK13648 104 D--------VAFGLENHA----VPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATS 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 181 GVDAVTEEAILRVLHELKKQGK-TVVVVHHDL-ETVRDyfDHLTLLNV-QVIASGPMEEVF 238
Cdd:PRK13648 172 MLDPDARQNLLDLVRKVKSEHNiTIISITHDLsEAMEA--DHVIVMNKgTVYKEGTPTEIF 230
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
19-243 3.53e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 90.68  E-value: 3.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKP-----ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVR----FFGQSLAQARKRI 89
Cdd:PRK13631  22 LRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQvgdiYIGDKKNNHELIT 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQ----------RGSVDWDFP------TSVLDVVMMGLYGqlgwFKRPGPREREAALRCLEQVSMQ-AFTTRQISQL 152
Cdd:PRK13631 102 NPYSKkiknfkelrrRVSMVFQFPeyqlfkDTIEKDIMFGPVA----LGVKKSEAKKLAKFYLNKMGLDdSYLERSPFGL 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIAS 231
Cdd:PRK13631 178 SGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKgKILKT 257
                        250
                 ....*....|..
gi 917519534 232 GPMEEVFTPENL 243
Cdd:PRK13631 258 GTPYEIFTDQHI 269
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
19-210 4.15e-21

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 86.35  E-value: 4.15e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFfgqslaQARKRIGYVPqrgsv 98
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW------GSTVKIGYFE----- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 dwdfptsvldvvmmglygqlgwfkrpgprereaalrcleqvsmqafttrqisQLSGGQQQRVFLARALAQDADLYFMDEP 178
Cdd:cd03221   70 ----------------------------------------------------QLSGGEKMRLALAKLLLENPNLLLLDEP 97
                        170       180       190
                 ....*....|....*....|....*....|..
gi 917519534 179 FAGVDAVTEEAILRVLHELKkqgKTVVVVHHD 210
Cdd:cd03221   98 TNHLDLESIEALEEALKEYP---GTVILVSHD 126
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
20-183 8.86e-21

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 91.34  E-value: 8.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  20 RVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLikavLGLVPVA----SGQVRFFGQSLAQAR------KRI 89
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSL----LSLIAGArkiqQGRVEVLGGDMADARhrravcPRI 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQrG---------SV--DWDFptsvldvvmMG-LYGQlgwfkrpGPREREAAL-RCLEQVSMQAFTTRQISQLSGGQ 156
Cdd:NF033858  79 AYMPQ-GlgknlyptlSVfeNLDF---------FGrLFGQ-------DAAERRRRIdELLRATGLAPFADRPAGKLSGGM 141
                        170       180
                 ....*....|....*....|....*..
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:NF033858 142 KQKLGLCCALIHDPDLLILDEPTTGVD 168
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
32-212 1.86e-20

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 86.62  E-value: 1.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF---------FGQSLAQARKRIGYVPQRgsvDWDF 102
Cdd:cd03290   15 ATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWsnknesepsFEATRSRNRYSVAYAAQK---PWLL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 PTSVLDVVMmglygqlgwFKRPGPREREAALrcLEQVSMQA------------FTTRQISqLSGGQQQRVFLARALAQDA 170
Cdd:cd03290   92 NATVEENIT---------FGSPFNKQRYKAV--TDACSLQPdidllpfgdqteIGERGIN-LSGGQRQRICVARALYQNT 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 917519534 171 DLYFMDEPFAGVDA-----VTEEAILRVLHELKkqgKTVVVVHHDLE 212
Cdd:cd03290  160 NIVFLDDPFSALDIhlsdhLMQEGILKFLQDDK---RTLVLVTHKLQ 203
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
13-239 2.42e-20

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 87.16  E-value: 2.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  13 SGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGyv 92
Cdd:COG4598    3 DTAPPALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDG-- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 pQRGSVD--------------------WDFPTsVLDVVMMGLYGQLGwfkRPGPREREAALRCLEQVSMQAFTTRQISQL 152
Cdd:COG4598   81 -ELVPADrrqlqrirtrlgmvfqsfnlWSHMT-VLENVIEAPVHVLG---RPKAEAIERAEALLAKVGLADKRDAYPAHL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDA--VTEeaILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVI- 229
Cdd:COG4598  156 SGGQQQRAAIARALAMEPEVMLFDEPTSALDPelVGE--VLKVMRDLAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIe 233
                        250
                 ....*....|
gi 917519534 230 ASGPMEEVFT 239
Cdd:COG4598  234 EQGPPAEVFG 243
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
9-236 2.96e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 89.34  E-value: 2.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   9 QHPESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL-----A 83
Cdd:PRK15439   2 QTSDTTAPPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCarltpA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 QARKR-IGYVPQRGSVdwdFPT-SVLDVVMMGLYgqlgwfKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVF 161
Cdd:PRK15439  82 KAHQLgIYLVPQEPLL---FPNlSVKENILFGLP------KRQASMQKMKQL--LAALGCQLDLDSSAGSLEVADRQIVE 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIA-SGPMEE 236
Cdd:PRK15439 151 ILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIAlSGKTAD 226
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
32-215 3.37e-20

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 89.58  E-value: 3.37e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGqslaqarkRIGYVPQrgsVDWDFPTSVLDVVM 111
Cdd:TIGR01271  440 PVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSG--------RISFSPQ---TSWIMPGTIKDNII 508
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   112 MGL-YGQLgwfkrpgpREREAALRCLEQVSMQAFTTRQIS-------QLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:TIGR01271  509 FGLsYDEY--------RYTSVIKACQLEEDIALFPEKDKTvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
                          170       180       190
                   ....*....|....*....|....*....|...
gi 917519534   184 AVTEEAIL-RVLHELKKQgKTVVVVHHDLETVR 215
Cdd:TIGR01271  581 VVTEKEIFeSCLCKLMSN-KTRILVTSKLEHLK 612
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
19-212 4.33e-20

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 85.79  E-value: 4.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDvdLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ---SLAQARKRIGYVPQR 95
Cdd:PRK10771   2 LKLTDITWLYHHLPMRFD--LTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQdhtTTPPSRRPVSMLFQE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  96 GSVdwdFP-TSVLDVVMMGLYgqlgwfkrPGPR----EREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:PRK10771  80 NNL---FShLTVAQNIGLGLN--------PGLKlnaaQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQ 148
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:PRK10771 149 PILLLDEPFSALDPALRQEMLTLVSQVcQERQLTLLMVSHSLE 191
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
32-190 4.50e-20

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 86.83  E-value: 4.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGqslaqarkRIGYVPQrgsVDWDFPTSVLDVVM 111
Cdd:cd03291   51 PVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG--------RISFSSQ---FSWIMPGTIKENII 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 MGL-YGQLgwfkrpgpREREAALRCLEQVSMQAFTTRQIS-------QLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:cd03291  120 FGVsYDEY--------RYKSVVKACQLEEDITKFPEKDNTvlgeggiTLSGGQRARISLARAVYKDADLYLLDSPFGYLD 191

                 ....*..
gi 917519534 184 AVTEEAI 190
Cdd:cd03291  192 VFTEKEI 198
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
19-223 5.96e-20

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 84.86  E-value: 5.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR-------IGY 91
Cdd:PRK13538   2 LEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEyhqdllyLGH 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPqrgsvdwdfptsvldvvmmGLYGQLG------WFKR-PGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLAR 164
Cdd:PRK13538  82 QP-------------------GIKTELTalenlrFYQRlHGPGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALAR 142
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 165 ALAQDADLYFMDEPF-----AGVDAVTEeailRVLHELKKQGKTVVVVHHDLETVRDYFDHLTL 223
Cdd:PRK13538 143 LWLTRAPLWILDEPFtaidkQGVARLEA----LLAQHAEQGGMVILTTHQDLPVASDKVRKLRL 202
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
36-210 6.44e-20

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 87.47  E-value: 6.44e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKrIGYVPQRGSVdwdFP-TSVLDVV 110
Cdd:PRK11432  24 NLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVThrsiQQRD-ICMVFQSYAL---FPhMSLGENV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 111 MMGLYGQlgwfKRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAI 190
Cdd:PRK11432 100 GYGLKML----GVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSM 175
                        170       180
                 ....*....|....*....|.
gi 917519534 191 LRVLHELKKQ-GKTVVVVHHD 210
Cdd:PRK11432 176 REKIRELQQQfNITSLYVTHD 196
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
19-253 7.43e-20

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 86.21  E-value: 7.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKriGYVPQRGSV 98
Cdd:PRK13638   2 LATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKR--GLLALRQQV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 DWDFPTSVLDVVMMGLYGQLGW-FKRPGPREREAALR---CLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:PRK13638  80 ATVFQDPEQQIFYTDIDSDIAFsLRNLGVPEAEITRRvdeALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 175 MDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPENLKRTYGERMRW 253
Cdd:PRK13638 160 LDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLrQGQILTHGAPGEVFACTEAMEQAGLTQPW 239
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
19-215 7.58e-20

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 84.91  E-value: 7.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPalWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS---LAQARKRIGYVPQR 95
Cdd:TIGR01277   1 LALDKVRYEYEHLP--MEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQShtgLAPYQRPVSMLFQE 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   96 GSVdwdFP-TSVLDVVMMGLYGQLgwfkRPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYF 174
Cdd:TIGR01277  79 NNL---FAhLTVRQNIGLGLHPGL----KLNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILL 151
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 917519534  175 MDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVR 215
Cdd:TIGR01277 152 LDEPFSALDPLLREEMLALVKQLCSERQrTLLMVTHHLSDAR 193
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
33-241 8.21e-20

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 88.06  E-value: 8.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS--GQVRFFGQSLaQAR-----KRIG---------YVPQrg 96
Cdd:PRK13549  20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTyeGEIIFEGEEL-QASnirdtERAGiaiihqelaLVKE-- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  97 svdwdfpTSVLDVVMMG----LYGQLGWfkrpgpreREAALRC---LEQVSMQAFTTRQISQLSGGQQQRVFLARALAQD 169
Cdd:PRK13549  97 -------LSVLENIFLGneitPGGIMDY--------DAMYLRAqklLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQ 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVFTPE 241
Cdd:PRK13549 162 ARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIrDGRHIGTRPAAGMTEDD 234
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
19-237 8.60e-20

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 85.65  E-value: 8.60e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS--------LAQARKRig 90
Cdd:TIGR02323   4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMRSgaelelyqLSEAERR-- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   91 yvpQRGSVDWDFPT-SVLDVVMMGLYGQLGWFKRP---GPRE----REAALRCLEQVSM-QAFTTRQISQLSGGQQQRVF 161
Cdd:TIGR02323  82 ---RLMRTEWGFVHqNPRDGLRMRVSAGANIGERLmaiGARHygniRATAQDWLEEVEIdPTRIDDLPRAFSGGMQQRLQ 158
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534  162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEV 237
Cdd:TIGR02323 159 IARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDlGLAVIIVTHDLGVARLLAQRLLVMQQgRVVESGLTDQV 236
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
39-217 1.15e-19

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 87.92  E-value: 1.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  39 LEVP-AGQLCAIVGPNGAGKSTLIKAVLG-LVP--------VASGQV--RFFG-------QSLAQARKRIGYVPQRgsVD 99
Cdd:COG1245   93 LPVPkKGKVTGILGPNGIGKSTALKILSGeLKPnlgdydeePSWDEVlkRFRGtelqdyfKKLANGEIKVAHKPQY--VD 170
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 100 wdfptsVLDVVMMGLYGQLgwFKRPGprEREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:COG1245  171 ------LIPKVFKGTVREL--LEKVD--ERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPS 240
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 917519534 180 AGVDaVTEE-AILRVLHELKKQGKTVVVVHHDLeTVRDY 217
Cdd:COG1245  241 SYLD-IYQRlNVARLIRELAEEGKYVLVVEHDL-AILDY 277
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
37-212 1.78e-19

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 84.06  E-value: 1.78e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  37 VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL--------AQAR-KRIGYVPQRGSVdwdFPT-SV 106
Cdd:PRK10584  29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLhqmdeearAKLRaKHVGFVFQSFML---IPTlNA 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 107 LDVVmmglygQLGWFKRpGPREREA---ALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:PRK10584 106 LENV------ELPALLR-GESSRQSrngAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178
                        170       180       190
                 ....*....|....*....|....*....|
gi 917519534 184 AVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:PRK10584 179 RQTGDKIADLLFSLnREHGTTLILVTHDLQ 208
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
15-216 1.88e-19

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 87.08  E-value: 1.88e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPLRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKR 88
Cdd:PRK10790 337 QSGRIDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSlshsvLRQG 416
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVDWDfptSVLDVVMMGlygqlgwfkrpgpRE--REAALRCLEQVSMQAFT--------TR---QISQLSGG 155
Cdd:PRK10790 417 VAMVQQDPVVLAD---TFLANVTLG-------------RDisEEQVWQALETVQLAELArslpdglyTPlgeQGNNLSVG 480
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 156 QQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVRD 216
Cdd:PRK10790 481 QKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH-TTLVVIAHRLSTIVE 540
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
34-215 2.16e-19

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 83.85  E-value: 2.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLglvpVASGQVRFFgQSL-AQARKRIGYVPqRGSVDW------------ 100
Cdd:cd03270   11 LKNVDVDIPRNKLVVITGVSGSGKSSLAFDTI----YAEGQRRYV-ESLsAYARQFLGQMD-KPDVDSieglspaiaidq 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 ----DFPTSVLDVVMmGLYGQLG-WFKRPGPREReaaLRCLEQVSMQAFT-TRQISQLSGGQQQRVFLARALAQDAD--L 172
Cdd:cd03270   85 kttsRNPRSTVGTVT-EIYDYLRlLFARVGIRER---LGFLVDVGLGYLTlSRSAPTLSGGEAQRIRLATQIGSGLTgvL 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:cd03270  161 YVLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDEDTIR 203
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
19-215 2.51e-19

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 84.21  E-value: 2.51e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS--------LAQARKRI- 89
Cdd:PRK11701   7 LSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDgqlrdlyaLSEAERRRl 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 -----GYVPQ------RGSVdwdfpTSVLDVV--MMGL----YGQLgwfkrpgpreREAALRCLEQVSMQAftTR---QI 149
Cdd:PRK11701  87 lrtewGFVHQhprdglRMQV-----SAGGNIGerLMAVgarhYGDI----------RATAGDWLERVEIDA--ARiddLP 149
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 150 SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVR 215
Cdd:PRK11701 150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLvRELGLAVVIVTHDLAVAR 216
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
36-237 5.88e-19

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 84.54  E-value: 5.88e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARK---------RIGYVPQRGSVdwdFP-TS 105
Cdd:PRK11144  16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKgiclppekrRIGYVFQDARL---FPhYK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VldvvmMG--LYGQlgwfkrpGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:PRK11144  93 V-----RGnlRYGM-------AKSMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLD 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 184 AVTEEAILRVLHELKKQGKT-VVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:PRK11144 161 LPRKRELLPYLERLAREINIpILYVSHSLDEILRLADRVVVLeQGKVKAFGPLEEV 216
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
19-239 7.28e-19

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 83.35  E-value: 7.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALW---------DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLaqarkri 89
Cdd:COG4167    5 LEVRNLSKTFKYRTGLFrrqqfeavkPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKL------- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 gyvpQRGsvdwDFPTSVLDVVMMglygqlgwFKRPG----PRER-----EAALRCLEQVSMQA-----FTT-RQ------ 148
Cdd:COG4167   78 ----EYG----DYKYRCKHIRMI--------FQDPNtslnPRLNigqilEEPLRLNTDLTAEEreeriFATlRLvgllpe 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 149 -----ISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLT 222
Cdd:COG4167  142 hanfyPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELqEKLGISYIYVSQHLGIVKHISDKVL 221
                        250
                 ....*....|....*...
gi 917519534 223 LL-NVQVIASGPMEEVFT 239
Cdd:COG4167  222 VMhQGEVVEYGKTAEVFA 239
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
19-215 1.15e-18

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 83.63  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALW-----------DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-- 85
Cdd:COG4608    8 LEVRDLKKHFPVRGGLFgrtvgvvkavdGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLsg 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 ------RKRIGYVPQ--RGSVDwdfP-TSVLDVVMMGL--YGQLGwfkRPGPREREAALrcLEQVSMQA-FTTRQISQLS 153
Cdd:COG4608   88 relrplRRRMQMVFQdpYASLN---PrMTVGDIIAEPLriHGLAS---KAERRERVAEL--LELVGLRPeHADRYPHEFS 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 154 GGQQQRVFLARALAQDADLYFMDEPFAGVDaVTEEA-ILRVLHELKKQ-GKTVVVVHHDLETVR 215
Cdd:COG4608  160 GGQRQRIGIARALALNPKLIVCDEPVSALD-VSIQAqVLNLLEDLQDElGLTYLFISHDLSVVR 222
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
14-239 1.21e-18

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 82.84  E-value: 1.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  14 GASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASG-----QVRFFGQSL------ 82
Cdd:PRK14271  17 AAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIfnyrdv 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  83 AQARKRIGYVPQRGSvdwDFPTSVLDVVMMGLYGQlgwfkRPGPRE--REAALRCLEQVSMQAFTTRQIS----QLSGGQ 156
Cdd:PRK14271  97 LEFRRRVGMLFQRPN---PFPMSIMDNVLAGVRAH-----KLVPRKefRGVAQARLTEVGLWDAVKDRLSdspfRLSGGQ 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVRDYFDHLTL-LNVQVIASGPME 235
Cdd:PRK14271 169 QQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALfFDGRLVEEGPTE 247

                 ....
gi 917519534 236 EVFT 239
Cdd:PRK14271 248 QLFS 251
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
19-224 1.43e-18

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 84.58  E-value: 1.43e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR---------- 88
Cdd:PRK11288   5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTaalaagvaii 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 ---IGYVPQrgsvdwdfpTSVLDVVMMG-LYGQLGWFKRPGPREReaALRCLEQVSMQAFTTRQISQLSGGQQQRVFLAR 164
Cdd:PRK11288  85 yqeLHLVPE---------MTVAENLYLGqLPHKGGIVNRRLLNYE--AREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAK 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 165 ALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:PRK11288 154 ALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVF 213
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
36-242 1.68e-18

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 83.93  E-value: 1.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA---------RKRIGYVPQRGSVdwdFP-TS 105
Cdd:PRK10070  46 DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKIsdaelrevrRKKIAMVFQSFAL---MPhMT 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VLDVVMMGLygQLGWFkrPGPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAV 185
Cdd:PRK10070 123 VLDNTAFGM--ELAGI--NAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPL 198
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 186 TEEAILRVLHELK-KQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVF-TPEN 242
Cdd:PRK10070 199 IRTEMQDELVKLQaKHQRTIVFISHDLDEAMRIGDRIAIMqNGEVVQVGTPDEILnNPAN 258
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
39-217 1.72e-18

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 82.03  E-value: 1.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  39 LEVPA-GQLCAIVGPNGAGKSTLIKAVLGLV----------PVASGQVRFFgqslaqarkrigyvpqRGSVDWDFPTSVL 107
Cdd:cd03236   20 LPVPReGQVLGLVGPNGIGKSTALKILAGKLkpnlgkfddpPDWDEILDEF----------------RGSELQNYFTKLL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 108 DvvmmglyGQLGWFKRPG-----PR--------------EREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:cd03236   84 E-------GDVKVIVKPQyvdliPKavkgkvgellkkkdERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALAR 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLeTVRDY 217
Cdd:cd03236  157 DADFYFFDEPSSYLDIKQRLNAARLIRELAEDDNYVLVVEHDL-AVLDY 204
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
33-212 2.51e-18

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 80.92  E-value: 2.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKaVLGLV-PVASGQVRFFG---------QSLAQARKRIGYVPQrgSVDWDF 102
Cdd:NF038007  20 VLNHLNFSVEKGDFVSIMGPSGSGKSTLLN-IIGMFdSLDSGSLTLAGkevtnlsysQKIILRRELIGYIFQ--SFNLIP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 PTSVLDVVMMGLygqlgwfKRPGPREREAALRCLEQVSMQAFTTR---QISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:NF038007  97 HLSIFDNVALPL-------KYRGVAKKERIERVNQVLNLFGIDNRrnhKPMQLSGGQQQRVAIARAMVSNPALLLADEPT 169
                        170       180       190
                 ....*....|....*....|....*....|...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:NF038007 170 GNLDSKNARAVLQQLKYINQKGTTIIMVTHSDE 202
PTZ00243 PTZ00243
ABC transporter; Provisional
11-214 3.27e-18

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 84.06  E-value: 3.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   11 PESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVrffgqslaQARKRIG 90
Cdd:PTZ00243  653 SERSAKTPKMKTDDFFELEPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV--------WAERSIA 724
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   91 YVPQRGsvdWDFPTSVLDVVMmglygqlgWFKrpgpREREAALRCLEQVSMQAFTTRQIS------------QLSGGQQQ 158
Cdd:PTZ00243  725 YVPQQA---WIMNATVRGNIL--------FFD----EEDAARLADAVRVSQLEADLAQLGggleteigekgvNLSGGQKA 789
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534  159 RVFLARALAQDADLYFMDEPFAGVDA-----VTEEAILRVLHelkkqGKTVVVVHHDLETV 214
Cdd:PTZ00243  790 RVSLARAVYANRDVYLLDDPLSALDAhvgerVVEECFLGALA-----GKTRVLATHQVHVV 845
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
19-238 3.31e-18

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 81.28  E-value: 3.31e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVvYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP----VASGQVRFFGQSLAQARKR---IGY 91
Cdd:PRK10418   5 IELRNIAL-QAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPVAPCALRgrkIAT 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRgsvdwdfPTSVLD-VVMMGLYGQLGWFKRPGPREREAALRCLEQV---------SMQAFttrqisQLSGGQQQRVF 161
Cdd:PRK10418  84 IMQN-------PRSAFNpLHTMHTHARETCLALGKPADDATLTAALEAVglenaarvlKLYPF------EMSGGMLQRMM 150
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEVF 238
Cdd:PRK10418 151 IALALLCEAPFIIADEPTTDLDVVAQARILDLLESIvQKRALGMLLVTHDMGVVARLADDVAVMsHGRIVEQGDVETLF 229
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
37-214 3.54e-18

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 83.42  E-value: 3.54e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  37 VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA----------------RKRIGYVPQRgsvdw 100
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRsprdairagimlcpedRKAEGIIPVH----- 346
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 101 dfptSV---LDVVMMGLYGQLGWFKRPGpREREAALRCLEQVSMQAFTTRQ-ISQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:PRK11288 347 ----SVadnINISARRHHLRAGCLINNR-WEAENADRFIRSLNIKTPSREQlIMNLSGGNQQKAILGRWLSEDMKVILLD 421
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 917519534 177 EPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETV 214
Cdd:PRK11288 422 EPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEV 459
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
4-211 3.54e-18

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 83.84  E-value: 3.54e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534     4 QPKTVQHP--ESGASSPLRVRDLTVVYR--EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG 79
Cdd:TIGR00957  620 EPDSIERRtiKPGEGNSITVHNATFTWArdLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG 699
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    80 QslaqarkrIGYVPQRGsvdWDFPTSVLDVVMMGLYGQLGWFKRPgpREREAALRCLEQVSMQAFTtrQISQ----LSGG 155
Cdd:TIGR00957  700 S--------VAYVPQQA---WIQNDSLRENILFGKALNEKYYQQV--LEACALLPDLEILPSGDRT--EIGEkgvnLSGG 764
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534   156 QQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILR--VLHELKKQGKTVVVVHHDL 211
Cdd:TIGR00957  765 QKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEhvIGPEGVLKNKTRILVTHGI 822
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
19-237 3.93e-18

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 83.31  E-value: 3.93e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGL--VPVASGQV----------------RFFGQ 80
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIiyhvalcekcgyverpSKVGE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   81 SL----------------------AQARKRIGYVPQRGSVDWDFPTsVLDVVMMGLYgQLGWfkrPGPREREAALRCLEQ 138
Cdd:TIGR03269  81 PCpvcggtlepeevdfwnlsdklrRRIRKRIAIMLQRTFALYGDDT-VLDNVLEALE-EIGY---EGKEAVGRAVDLIEM 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  139 VSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDY 217
Cdd:TIGR03269 156 VQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAvKASGISMVLTSHWPEVIEDL 235
                         250       260
                  ....*....|....*....|.
gi 917519534  218 FDHLTLL-NVQVIASGPMEEV 237
Cdd:TIGR03269 236 SDKAIWLeNGEIKEEGTPDEV 256
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
39-234 4.59e-18

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 80.53  E-value: 4.59e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  39 LEVPAG-----QLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSlaqarkrIGYVPQRgsVDWDFPTSVLDVVM-- 111
Cdd:cd03237   15 LEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT-------VSYKPQY--IKADYEGTVRDLLSsi 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 -MGLYGQLGWfkrpgprEREAAlrclEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAI 190
Cdd:cd03237   86 tKDFYTHPYF-------KTEIA----KPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMA 154
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 191 LRVL-HELKKQGKTVVVVHHDLeTVRDYF-DHLTLLN----VQVIASGPM 234
Cdd:cd03237  155 SKVIrRFAENNEKTAFVVEHDI-IMIDYLaDRLIVFEgepsVNGVANPPQ 203
cbiO PRK13644
energy-coupling factor transporter ATPase;
19-244 5.04e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 81.19  E-value: 5.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG------QSLAQARKRIGY 91
Cdd:PRK13644   2 IRLENVSYSYPDgTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGidtgdfSKLQGIRKLVGI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWDFPTSVLDVVMmglygqlgwfkrpGPRE--------REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLA 163
Cdd:PRK13644  82 VFQNPETQFVGRTVEEDLAF-------------GPENlclppieiRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALA 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 164 RALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVFTPENL 243
Cdd:PRK13644 149 GILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHDADRIIVMDRGKIVLEGEPENVLSDVSL 228

                 .
gi 917519534 244 K 244
Cdd:PRK13644 229 Q 229
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
34-224 5.76e-18

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 80.89  E-value: 5.76e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR----------------IGYVPQRGS 97
Cdd:PRK10419  28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAqrkafrrdiqmvfqdsISAVNPRKT 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 VDWdfptsVLDVVMMGLYGQlgwfkrpGPREREA-ALRCLEQVSMQA-FTTRQISQLSGGQQQRVFLARALAQDADLYFM 175
Cdd:PRK10419 108 VRE-----IIREPLRHLLSL-------DKAERLArASEMLRAVDLDDsVLDKRPPQLSGGQLQRVCLARALAVEPKLLIL 175
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 176 DEPFAGVDAVTEEAILRVLHELKKQGKTV-VVVHHDLETVRdYFDHLTLL 224
Cdd:PRK10419 176 DEAVSNLDLVLQAGVIRLLKKLQQQFGTAcLFITHDLRLVE-RFCQRVMV 224
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
37-239 6.06e-18

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 81.49  E-value: 6.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  37 VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP----VASGQVRFFGQSL----AQARKRIgyVPQRGSVDWDFPTSVLD 108
Cdd:COG4170   26 VSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLlklsPRERRKI--IGREIAMIFQEPSSCLD 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 109 VvMMGLYGQL-----------GWFKRPGPReREAALRCLEQVS-------MQAFTtrqiSQLSGGQQQRVFLARALAQDA 170
Cdd:COG4170  104 P-SAKIGDQLieaipswtfkgKWWQRFKWR-KKRAIELLHRVGikdhkdiMNSYP----HELTEGECQKVMIAMAIANQP 177
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKK-QGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT 239
Cdd:COG4170  178 RLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHDLESISQWADTITVLYCgQTVESGPTEQILK 248
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
34-212 6.08e-18

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 80.20  E-value: 6.08e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRIGYVPQRGSVdwdFP-TSVLDVVMM 112
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMVVFQNYSL---LPwLTVRENIAL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  113 GLYGQLGWFKRPgprEREAALR-CLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAIL 191
Cdd:TIGR01184  78 AVDRVLPDLSKS---ERRAIVEeHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQ 154
                         170       180
                  ....*....|....*....|..
gi 917519534  192 RVLHEL-KKQGKTVVVVHHDLE 212
Cdd:TIGR01184 155 EELMQIwEEHRVTVLMVTHDVD 176
cbiO PRK13642
energy-coupling factor transporter ATPase;
19-243 6.21e-18

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 80.91  E-value: 6.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKP---ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-----QARKRIG 90
Cdd:PRK13642   5 LEVENLVFKYEKESdvnQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTaenvwNLRRKIG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQrgSVDWDF-PTSVLDVVMMGLYGQlgwfkrPGPRER--EAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALA 167
Cdd:PRK13642  85 MVFQ--NPDNQFvGATVEDDVAFGMENQ------GIPREEmiKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIA 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 168 QDADLYFMDEPFAGVDAVTEEAILRVLHELK-KQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVF-TPENL 243
Cdd:PRK13642 157 LRPEIIILDESTSMLDPTGRQEIMRVIHEIKeKYQLTVLSITHDLDEAASSDRILVMKAGEIIKEAAPSELFaTSEDM 234
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
19-221 6.30e-18

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 78.35  E-value: 6.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE-KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFfgqslaQARKRIGYVPQRGS 97
Cdd:cd03223    1 IELENLSLATPDgRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM------PEGEDLLFLPQRPY 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 vdwdFPTSVLdvvmmglygqlgwfkrpgpreREAALRCLEQVsmqafttrqisqLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:cd03223   75 ----LPLGTL---------------------REQLIYPWDDV------------LSGGEQQRLAFARLLLHKPKFVFLDE 117
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 917519534 178 PFAGVDAVTEEAILRVLHELkkqGKTVVVVHHDlETVRDYFDHL 221
Cdd:cd03223  118 ATSALDEESEDRLYQLLKEL---GITVISVGHR-PSLWKFHDRV 157
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
44-217 6.79e-18

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 82.55  E-value: 6.79e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  44 GQLCAIVGPNGAGKSTLIKAVLG-LVP--------VASGQV--RFFG-------QSLAQARKRIGYVPQRgsVDwdfpts 105
Cdd:PRK13409  99 GKVTGILGPNGIGKTTAVKILSGeLIPnlgdyeeePSWDEVlkRFRGtelqnyfKKLYNGEIKVVHKPQY--VD------ 170
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VLDVVMMGLYGQLgwFKRPGprEREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAV 185
Cdd:PRK13409 171 LIPKVFKGKVREL--LKKVD--ERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIR 246
                        170       180       190
                 ....*....|....*....|....*....|..
gi 917519534 186 TEEAILRVLHELKKqGKTVVVVHHDLeTVRDY 217
Cdd:PRK13409 247 QRLNVARLIRELAE-GKYVLVVEHDL-AVLDY 276
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
39-211 8.28e-18

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 82.52  E-value: 8.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  39 LEVPAGQL-----CAIVGPNGAGKSTLIKAVLGLVPVASGQVrffgqslaQARKRIGYVPQRGSVDwdFPTSVLDVVMMG 113
Cdd:COG1245  356 LEVEGGEIregevLGIVGPNGIGKTTFAKILAGVLKPDEGEV--------DEDLKISYKPQYISPD--YDGTVEEFLRSA 425
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 114 LYGQLG--WFK----RPgprereaaLRcLEQVsMQafttRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAvtE 187
Cdd:COG1245  426 NTDDFGssYYKteiiKP--------LG-LEKL-LD----KNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV--E 489
                        170       180       190
                 ....*....|....*....|....*....|
gi 917519534 188 E------AILRVlheLKKQGKTVVVVHHDL 211
Cdd:COG1245  490 QrlavakAIRRF---AENRGKTAMVVDHDI 516
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
30-216 9.78e-18

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 79.23  E-value: 9.78e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP--VASGQVRFFGQSLAQARKRIGYVPQRGsvdwDFPTSVL 107
Cdd:COG2401   42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQFGREASLIDAIGRKG----DFKDAVE 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 108 DVVMMGLYGQLGWFKRPgprereaalrcleqvsmqafttrqiSQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTE 187
Cdd:COG2401  118 LLNAVGLSDAVLWLRRF-------------------------KELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTA 172
                        170       180       190
                 ....*....|....*....|....*....|
gi 917519534 188 EAILRVLHEL-KKQGKTVVVVHHDLETVRD 216
Cdd:COG2401  173 KRVARNLQKLaRRAGITLVVATHHYDVIDD 202
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
39-211 9.81e-18

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 82.16  E-value: 9.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  39 LEVPAGQL-----CAIVGPNGAGKSTLIKAVLGLVPVASGQVrffgqslaQARKRIGYVPQRgsVDWDFPTSVlDVVMMG 113
Cdd:PRK13409 355 LEVEGGEIyegevIGIVGPNGIGKTTFAKLLAGVLKPDEGEV--------DPELKISYKPQY--IKPDYDGTV-EDLLRS 423
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 114 LYGQLG--WFK----RPgprereaaLRcLEQVsMQafttRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD---- 183
Cdd:PRK13409 424 ITDDLGssYYKseiiKP--------LQ-LERL-LD----KNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDveqr 489
                        170       180
                 ....*....|....*....|....*....
gi 917519534 184 -AVTeEAILRVLHElkkQGKTVVVVHHDL 211
Cdd:PRK13409 490 lAVA-KAIRRIAEE---REATALVVDHDI 514
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
19-210 1.53e-17

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 81.52  E-value: 1.53e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRfFGQSLaqarkRIGYVPQ-RGS 97
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIE-IGETV-----KLAYVDQsRDA 396
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   98 VD-----WDFPTSVLDVVMMGLY-----GQLGWFKRPGPREReaalrcleqvsmqafttRQISQLSGGQQQRVFLARALA 167
Cdd:TIGR03719 397 LDpnktvWEEISGGLDIIKLGKReipsrAYVGRFNFKGSDQQ-----------------KKVGQLSGGERNRVHLAKTLK 459
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 917519534  168 QDADLYFMDEPFAGVDAVTeeaiLRVLHE-LKKQGKTVVVVHHD 210
Cdd:TIGR03719 460 SGGNVLLLDEPTNDLDVET----LRALEEaLLNFAGCAVVISHD 499
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
19-214 1.58e-17

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 78.67  E-value: 1.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPA---LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ-----ARKRIG 90
Cdd:cd03248   12 VKFQNVTFAYPTRPDtlvLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQyehkyLHSKVS 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRGSVdwdFPTSVLDVVMMGLYGqlgwfkRPGPREREAALRCLEQVSMQAF-------TTRQISQLSGGQQQRVFLA 163
Cdd:cd03248   92 LVGQEPVL---FARSLQDNIAYGLQS------CSFECVKEAAQKAHAHSFISELasgydteVGEKGSQLSGGQKQRVAIA 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 917519534 164 RALAQDADLYFMDEPFAGVDAVTEEAILRVLHElKKQGKTVVVVHHDLETV 214
Cdd:cd03248  163 RALIRNPQVLILDEATSALDAESEQQVQQALYD-WPERRTVLVIAHRLSTV 212
GguA NF040905
sugar ABC transporter ATP-binding protein;
33-224 1.93e-17

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 80.99  E-value: 1.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS--------GQVRFFG--------------QSLA------- 83
Cdd:NF040905  16 ALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSyegeilfdGEVCRFKdirdsealgiviihQELAlipylsi 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 ---------QARkrigyvpqRGSVDWDfptsvldvvmmglygqlgwfkrpgpREREAALRCLEQVSMQAFTTRQISQLSG 154
Cdd:NF040905  96 aeniflgneRAK--------RGVIDWN-------------------------ETNRRARELLAKVGLDESPDTLVTDIGV 142
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 155 GQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:NF040905 143 GKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVL 212
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
15-232 1.99e-17

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 81.29  E-value: 1.99e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  15 ASSPL-RVRDLTVVYR----EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVA-----SGQVRFFGQSLAQ 84
Cdd:PRK15134   1 MTQPLlAIENLSVAFRqqqtVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPpvvypSGDIRFHGESLLH 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  85 ARK---------RIGYVPQRGSVDWDfPtsvLDVVMMGLYGQLGWFKrpGPReREAA----LRCLEQVSMQAFTTRQIS- 150
Cdd:PRK15134  81 ASEqtlrgvrgnKIAMIFQEPMVSLN-P---LHTLEKQLYEVLSLHR--GMR-REAArgeiLNCLDRVGIRQAAKRLTDy 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 151 --QLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDhltllNVQ 227
Cdd:PRK15134 154 phQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLAD-----RVA 228

                 ....*
gi 917519534 228 VIASG 232
Cdd:PRK15134 229 VMQNG 233
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
31-217 2.16e-17

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 78.38  E-value: 2.16e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  31 KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--------RKRIGYVPQRGSVDWDf 102
Cdd:PRK10908  15 RQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLknrevpflRRQIGMIFQDHHLLMD- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 103 pTSVLDVVMMGLYgqLGWFKRPGPREREAAlrCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGV 182
Cdd:PRK10908  94 -RTVYDNVAIPLI--IAGASGDDIRRRVSA--ALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNL 168
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 917519534 183 DAVTEEAILRVLHELKKQGKTVVVVHHDLETV--RDY 217
Cdd:PRK10908 169 DDALSEGILRLFEEFNRVGVTVLMATHDIGLIsrRSY 205
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
38-237 2.21e-17

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 80.83  E-value: 2.21e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  38 DLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQV-----RFFGQSLAQARKRIGYVPQRGSVDW------DFPTSV 106
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERqsqfsHITRLSFEQLQKLVSDEWQRNNTDMlspgedDTGRTT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 107 LDVVMMGLygqlgwfkrpgprerEAALRCLE---QVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:PRK10938 103 AEIIQDEV---------------KDPARCEQlaqQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLD 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 184 AVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:PRK10938 168 VASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLaDCTLAETGEREEI 222
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
19-217 2.98e-17

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 77.68  E-value: 2.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS----LAQARKRIGYVPQ 94
Cdd:PRK13540   2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSikkdLCTYQKQLCFVGH 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDwdfPTSVL-DVVMMGLYGQLGwfkrpgprereaALRCLEQV---SMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:PRK13540  82 RSGIN---PYLTLrENCLYDIHFSPG------------AVGITELCrlfSLEHLIDYPCGLLSSGQKRQVALLRLWMSKA 146
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 917519534 171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV-HHDLETVR-DY 217
Cdd:PRK13540 147 KLWLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTsHQDLPLNKaDY 195
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
30-236 3.67e-17

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 80.53  E-value: 3.67e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----RKRIGYVPQrgsVDWDFPT 104
Cdd:PRK10789 327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLqldswRSRLAVVSQ---TPFLFSD 403
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 105 SVLDVVMMGlygqlgwfkRPGPR----EREAALRCLEQVSM---QAFTTrQISQ----LSGGQQQRVFLARALAQDADLY 173
Cdd:PRK10789 404 TVANNIALG---------RPDATqqeiEHVARLASVHDDILrlpQGYDT-EVGErgvmLSGGQKQRISIARALLLNAEIL 473
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 174 FMDEPFAGVDAVTEEAILRVLHELkKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEE 236
Cdd:PRK10789 474 ILDDALSAVDGRTEHQILHNLRQW-GEGRTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQ 535
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
19-235 4.83e-17

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 77.80  E-value: 4.83e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGL--VPVASGQVRFFGQSLAQ------ARKRIG 90
Cdd:COG0396    1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILElspderARAGIF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRgsvdwdfPTSVLDVVMMGL----YGQLGWFKRPGPREREAALRCLEQVSM-QAFTTRQISQ-LSGGQQQRVFLAR 164
Cdd:COG0396   81 LAFQY-------PVEIPGVSVSNFlrtaLNARRGEELSAREFLKLLKEKMKELGLdEDFLDRYVNEgFSGGEKKRNEILQ 153
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 165 ALAQDADLYFMDEPFAG--VDAVteEAILRVLHELKKQGKTVVVV-HHD--LETVRDYFDHLtLLNVQVIASGPME 235
Cdd:COG0396  154 MLLLEPKLAILDETDSGldIDAL--RIVAEGVNKLRSPDRGILIItHYQriLDYIKPDFVHV-LVDGRIVKSGGKE 226
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
19-214 5.40e-17

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 80.06  E-value: 5.40e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-----SLAQARKRIGY 91
Cdd:PRK11176 342 IEFRNVTFTYpgKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHdlrdyTLASLRNQVAL 421
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVdwdFPTSVLDVVMmglYGQLGWFKRpgpREREAALRcleqvsmQAFTTRQISQ---------------LSGGQ 156
Cdd:PRK11176 422 VSQNVHL---FNDTIANNIA---YARTEQYSR---EQIEEAAR-------MAYAMDFINKmdngldtvigengvlLSGGQ 485
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 157 QQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETV 214
Cdd:PRK11176 486 RQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKN-RTSLVIAHRLSTI 542
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
33-236 9.76e-17

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 79.28  E-value: 9.76e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKR------IGYVPQRGSVdwdFPT-S 105
Cdd:PRK10762  19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKssqeagIGIIHQELNL---IPQlT 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 106 VLDVVMMG-----LYGQLGWfkrpgPREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPfa 180
Cdd:PRK10762  96 IAENIFLGrefvnRFGRIDW-----KKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEP-- 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 181 gVDAVTE---EAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEE 236
Cdd:PRK10762 169 -TDALTDtetESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFrDGQFIAEREVAD 227
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
11-208 1.90e-16

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 75.66  E-value: 1.90e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  11 PESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-RKR- 88
Cdd:PRK13543   4 PLHTAPPLLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGdRSRf 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVDWDFPTSVLDVVMMGLYGQlgwfkrpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:PRK13543  84 MAYLGHLPGLKADLSTLENLHFLCGLHGR---------RAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLS 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 917519534 169 DADLYFMDEPFAGVDAvteEAILRVLH----ELKKQGKTVVVVH 208
Cdd:PRK13543 155 PAPLWLLDEPYANLDL---EGITLVNRmisaHLRGGGAALVTTH 195
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
31-224 2.48e-16

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 74.97  E-value: 2.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  31 KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKaVL------GLVpvaSGQVRFFGQSLAQA-RKRIGYVPQrgsVDWDFP 103
Cdd:cd03232   20 RQLLNNISGYVKPGTLTALMGESGAGKTTLLD-VLagrktaGVI---TGEILINGRPLDKNfQRSTGYVEQ---QDVHSP 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 104 TSVLDVVMmglygqlgwfkrpgprEREAALRcleqvsmqafttrqisQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:cd03232   93 NLTVREAL----------------RFSALLR----------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLD 140
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 917519534 184 AVTEEAILRVLHELKKQGKTVVV-VHHDLETVRDYFDHLTLL 224
Cdd:cd03232  141 SQAAYNIVRFLKKLADSGQAILCtIHQPSASIFEKFDRLLLL 182
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
36-210 4.16e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 76.61  E-value: 4.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ---SLAQARKRIGYVPQRGSVdwdFP-TSVLDVVM 111
Cdd:PRK11000  21 DINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKrmnDVPPAERGVGMVFQSYAL---YPhLSVAENMS 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 MGLygqlgwfKRPGPREREAALRcLEQVS----MQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVte 187
Cdd:PRK11000  98 FGL-------KLAGAKKEEINQR-VNQVAevlqLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAA-- 167
                        170       180       190
                 ....*....|....*....|....*....|.
gi 917519534 188 eaiLRV--------LHelKKQGKTVVVVHHD 210
Cdd:PRK11000 168 ---LRVqmrieisrLH--KRLGRTMIYVTHD 193
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
30-238 4.48e-16

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 75.89  E-value: 4.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG------QSLAQARKRIGYVPQRgsvdwdfP 103
Cdd:PRK13633  22 EKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldtsdeENLWDIRNKAGMVFQN-------P 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 104 ------TSVLDVVMMGLYgQLGwfkrPGPRE-REAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:PRK13633  95 dnqivaTIVEEDVAFGPE-NLG----IPPEEiRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFD 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 177 EPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNVQVIASGPMEEVF 238
Cdd:PRK13633 170 EPTAMLDPSGRREVVNTIKELnKKYGITIILITHYMEEAVEADRIIVMDSGKVVMEGTPKEIF 232
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
37-220 4.75e-16

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 77.15  E-value: 4.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  37 VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARkRIGYvPQRGSV---D-WDFPTsvldvvmm 112
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADN-REAY-RQLFSAvfsDfHLFDR-------- 420
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 113 gLYGqlgwfkRPGPREREAALRCLEQVSMQ--------AFTTRQISQlsgGQQQRVFLARALAQDADLYFMDEPFAGVDA 184
Cdd:COG4615  421 -LLG------LDGEADPARARELLERLELDhkvsvedgRFSTTDLSQ---GQRKRLALLVALLEDRPILVFDEWAADQDP 490
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 185 V------TEeailrVLHELKKQGKTVVVVHHDletvrD-YFDH 220
Cdd:COG4615  491 EfrrvfyTE-----LLPELKARGKTVIAISHD-----DrYFDL 523
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
9-243 6.38e-16

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 77.07  E-value: 6.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    9 QHPESGASSPLRV------RDLTVVY---REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFG 79
Cdd:TIGR00958 463 NIPLTGTLAPLNLegliefQDVSFSYpnrPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG 542
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   80 QSLAQ-----ARKRIGYVPQRGSVdwdFPTSVLDVVMMGLYgqlgwfKRPGPREREAALRCLEQVSMQAFTT-------R 147
Cdd:TIGR00958 543 VPLVQydhhyLHRQVALVGQEPVL---FSGSVRENIAYGLT------DTPDEEIMAAAKAANAHDFIMEFPNgydtevgE 613
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  148 QISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAilrvLHELKK-QGKTVVVVHHDLETVRDyfdhltLLNV 226
Cdd:TIGR00958 614 KGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQL----LQESRSrASRTVLLIAHRLSTVER------ADQI 683
                         250
                  ....*....|....*..
gi 917519534  227 QVIASGPMEEVFTPENL 243
Cdd:TIGR00958 684 LVLKKGSVVEMGTHKQL 700
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
37-237 6.81e-16

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 76.76  E-value: 6.81e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   37 VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQV--------------RFFGQslAQARKRIGYVPQRGSVdwdF 102
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnvrvgdewvdmtkpGPDGR--GRAKRYIGILHQEYDL---Y 377
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  103 P-TSVLDVVMMGLYGQLgwfkrPGPREREAALRCLEQVSMQAFTTRQI-----SQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:TIGR03269 378 PhRTVLDNLTEAIGLEL-----PDELARMKAVITLKMVGFDEEKAEEIldkypDELSEGERHRVALAQVLIKEPRIVILD 452
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534  177 EPFAGVDAVTEEAILR-VLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEEV 237
Cdd:TIGR03269 453 EPTGTMDPITKVDVTHsILKAREEMEQTFIIVSHDMDFVLDVCDRAALMrDGKIVKIGDPEEI 515
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
19-215 7.76e-16

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 76.63  E-value: 7.76e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTvvyreKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIG--YV 92
Cdd:PRK15439 269 LTVEDLT-----GEGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINalstAQRLARGlvYL 343
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 P---QRGSVDWDFPTSvLDVVMMgLYGQLGWFKRPGpREREAALRCLEQVSMQAFTTRQ-ISQLSGGQQQRVFLARALAQ 168
Cdd:PRK15439 344 PedrQSSGLYLDAPLA-WNVCAL-THNRRGFWIKPA-RENAVLERYRRALNIKFNHAEQaARTLSGGNQQKVLIAKCLEA 420
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:PRK15439 421 SPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIE 467
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
19-212 8.29e-16

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 74.74  E-value: 8.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVY-----REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKRIGY 91
Cdd:COG1101    2 LELKNLSKTFnpgtvNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKlpEYKRAKY 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 V------PQRGSvdwdFPT-SVLDVVMMGLY-GQLGWFKRPGPREREAALRclEQVS---------MQAfttrQISQLSG 154
Cdd:COG1101   82 IgrvfqdPMMGT----APSmTIEENLALAYRrGKRRGLRRGLTKKRRELFR--ELLAtlglglenrLDT----KVGLLSG 151
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 155 GQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLE 212
Cdd:COG1101  152 GQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIvEENNLTTLMVTHNME 210
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
19-235 8.66e-16

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 74.22  E-value: 8.66e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG--LVPVASGQVRFFGQSLAQ------ARKRIG 90
Cdd:TIGR01978   1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGhpSYEVTSGTILFKGQDLLElepderARAGLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   91 YVPQR-----GSVDWDFPTSVLDVVMMglYGQLGWFKRPGPRER-EAALRCLEQVsmQAFTTRQISQ-LSGGQQQRVFLA 163
Cdd:TIGR01978  81 LAFQYpeeipGVSNLEFLRSALNARRS--ARGEEPLDLLDFEKLlKEKLALLDMD--EEFLNRSVNEgFSGGEKKRNEIL 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534  164 RALAQDADLYFMDEPFAG--VDAVteEAILRVLHELKKQGKTVVVVHHD---LETVRDYFDHLtLLNVQVIASGPME 235
Cdd:TIGR01978 157 QMALLEPKLAILDEIDSGldIDAL--KIVAEGINRLREPDRSFLIITHYqrlLNYIKPDYVHV-LLDGRIVKSGDVE 230
cbiO PRK13645
energy-coupling factor transporter ATPase;
30-243 1.36e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 74.66  E-value: 1.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  30 EKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVrFFG-----------QSLAQARKRIGYVPQrgsv 98
Cdd:PRK13645  23 EFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQT-IVGdyaipanlkkiKEVKRLRKEIGLVFQ---- 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 dwdFPTSVL-------DV----VMMGLYGQLGWFKRPgprereaalRCLEQVSM-QAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:PRK13645  98 ---FPEYQLfqetiekDIafgpVNLGENKQEAYKKVP---------ELLKLVQLpEDYVKRSPFELSGGQKRRVALAGII 165
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFTPENL 243
Cdd:PRK13645 166 AMDGNTLVLDEPTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIADEVIVMHEgKVISIGSPFEIFSNQEL 244
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
21-248 1.95e-15

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 75.82  E-value: 1.95e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    21 VRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ----SLAQARKRIGYVPQ 94
Cdd:TIGR01257  931 VKNLVKIFEPsgRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKdietNLDAVRQSLGMCPQ 1010
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    95 RGSVDWDFptSVLDVVMmgLYGQLgwfkrPGPREREAALRC---LEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDAD 171
Cdd:TIGR01257 1011 HNILFHHL--TVAEHIL--FYAQL-----KGRSWEEAQLEMeamLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAK 1081
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   172 LYFMDEPFAGVDAVTEEAILRVLheLK-KQGKTVVVVHHdletvrdYFDHLTLLN--VQVIASGPMEEVFTPENLKRTYG 248
Cdd:TIGR01257 1082 VVVLDEPTSGVDPYSRRSIWDLL--LKyRSGRTIIMSTH-------HMDEADLLGdrIAIISQGRLYCSGTPLFLKNCFG 1152
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
33-224 2.25e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.21  E-value: 2.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYVPQRGSVDWDFptSV 106
Cdd:PRK09700  20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKldhklaAQLGIGIIYQELSVIDEL--TV 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 107 LDVVMMG------LYGQ--LGWFKRpgpREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEP 178
Cdd:PRK09700  98 LENLYIGrhltkkVCGVniIDWREM---RVRAAMM--LLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEP 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 179 FAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:PRK09700 173 TSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM 218
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
21-211 2.79e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 74.82  E-value: 2.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  21 VRDLTvvYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA------QARKRIGYVPQ 94
Cdd:PRK09700 268 VRNVT--SRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISprspldAVKKGMAYITE 345
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  95 RGSVDWDFPT-------SVLDVVMMGLY-GQLGWFKRPgpREREAALRCLEQVSMQAFTTRQ-ISQLSGGQQQRVFLARA 165
Cdd:PRK09700 346 SRRDNGFFPNfsiaqnmAISRSLKDGGYkGAMGLFHEV--DEQRTAENQRELLALKCHSVNQnITELSGGNQQKVLISKW 423
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDL 211
Cdd:PRK09700 424 LCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSEL 469
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
29-221 5.38e-15

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 70.47  E-value: 5.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  29 REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLglvpvasgqvrfFGQSLAQARKRIGYVPQRGSVdwdfptsvld 108
Cdd:cd03227    6 RFPSYFVPNDVTFGEGSLTIITGPNGSGKSTILDAIG------------LALGGAQSATRRRSGVKAGCI---------- 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 109 vvmmglygqlgwfkrpgprerEAAlrcleqVSMQAFTTRqiSQLSGGQQQRVFLARALA----QDADLYFMDEPFAGVDA 184
Cdd:cd03227   64 ---------------------VAA------VSAELIFTR--LQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLDP 114
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 917519534 185 VTEEAILRVLHELKKQGKTVVVVHHDLETVRDYfDHL 221
Cdd:cd03227  115 RDGQALAEAILEHLVKGAQVIVITHLPELAELA-DKL 150
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
19-210 7.76e-15

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 72.95  E-value: 7.76e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK-PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQARKRigyvpQRgs 97
Cdd:PRK11650   4 LKLQAVRKSYDGKtQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPA-----DR-- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 vdwdfptsvlDVVM----------MGLYGQLGW------FKRPGPRER-EAALRCLEqvsMQAFTTRQISQLSGGQQQRV 160
Cdd:PRK11650  77 ----------DIAMvfqnyalyphMSVRENMAYglkirgMPKAEIEERvAEAARILE---LEPLLDRKPRELSGGQRQRV 143
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVteeaiLRV-----LHELKKQ-GKTVVVVHHD 210
Cdd:PRK11650 144 AMGRAIVREPAVFLFDEPLSNLDAK-----LRVqmrleIQRLHRRlKTTSLYVTHD 194
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
12-239 1.01e-14

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 73.20  E-value: 1.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  12 ESGASSPLRVRDLTVVY-----------REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPvASGQVRFFGQ 80
Cdd:PRK15134 269 PEPASPLLDVEQLQVAFpirkgilkrtvDHNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQ 347
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  81 SLAQ-ARKRIGYVPQRGSVDWDFPTS-------VLDVVMMGL---YGQLGwfkrpgPREREAA-LRCLEQVSMQAFTT-R 147
Cdd:PRK15134 348 PLHNlNRRQLLPVRHRIQVVFQDPNSslnprlnVLQIIEEGLrvhQPTLS------AAQREQQvIAVMEEVGLDPETRhR 421
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 148 QISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGK-TVVVVHHDLETVRDYFDHLTLLNV 226
Cdd:PRK15134 422 YPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQlAYLFISHDLHVVRALCHQVIVLRQ 501
                        250
                 ....*....|....
gi 917519534 227 -QVIASGPMEEVFT 239
Cdd:PRK15134 502 gEVVEQGDCERVFA 515
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
33-236 1.16e-14

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 72.84  E-value: 1.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQS-------------LAQARKRIGYVPQRgsvd 99
Cdd:PRK10982  13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEidfksskealengISMVHQELNLVLQR---- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 100 wdfptSVLDVVMMGLYGQLGWFKRPGPREREAAlRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:PRK10982  89 -----SVMDNMWLGRYPTKGMFVDQDKMYRDTK-AIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPT 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLL-NVQVIASGPMEE 236
Cdd:PRK10982 163 SSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILrDGQWIATQPLAG 220
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
26-210 2.57e-14

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 71.89  E-value: 2.57e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   26 VVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLvpvasgQVRFFGQSLAQARKRIGYVPQRGSVDwdfPT- 104
Cdd:TIGR03719  13 VVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV------DKDFNGEARPQPGIKVGYLPQEPQLD---PTk 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  105 SVLDVVMMGLygqlgwfkrpgpREREAALRCLEQVSMQ---------AFTTRQ--------------------------- 148
Cdd:TIGR03719  84 TVRENVEEGV------------AEIKDALDRFNEISAKyaepdadfdKLAAEQaelqeiidaadawdldsqleiamdalr 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534  149 -------ISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKkqgKTVVVVHHD 210
Cdd:TIGR03719 152 cppwdadVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYP---GTVVAVTHD 217
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
19-214 1.05e-13

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 70.34  E-value: 1.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLT---VVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVAS-GQVRFFGQSL-----AQA---- 85
Cdd:PRK13549 260 LEVRNLTawdPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRWeGEIFIDGKPVkirnpQQAiaqg 339
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 -------RKRIGYVPQRGsVDWDFPTSVLDVvmmglygqlgwFKRPGPREREAALRCLEQvSMQAFTTR------QISQL 152
Cdd:PRK13549 340 iamvpedRKRDGIVPVMG-VGKNITLAALDR-----------FTGGSRIDDAAELKTILE-SIQRLKVKtaspelAIARL 406
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETV 214
Cdd:PRK13549 407 SGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEV 468
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
19-215 1.20e-13

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 69.35  E-value: 1.20e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR---------EKP----ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-- 83
Cdd:PRK15079   9 LEVADLKVHFDikdgkqwfwQPPktlkAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLgm 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  84 ------QARKRIGYVPQRGSVDWDFPTSVLDVVMMGL---YGQLgwfKRPGPREREAALrcLEQVSM-QAFTTRQISQLS 153
Cdd:PRK15079  89 kddewrAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLrtyHPKL---SRQEVKDRVKAM--MLKVGLlPNLINRYPHEFS 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917519534 154 GGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVR 215
Cdd:PRK15079 164 GGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVK 226
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
19-249 1.42e-13

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 70.43  E-value: 1.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    19 LRVRDLTVVY--REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL----AQARKRIGYV 92
Cdd:TIGR01257 1938 LRLNELTKVYsgTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSIltniSDVHQNMGYC 2017
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    93 PQRGSVDwDFPTSVLDVVmmgLYGQLgwfkRPGPRER--EAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDA 170
Cdd:TIGR01257 2018 PQFDAID-DLLTGREHLY---LYARL----RGVPAEEieKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCP 2089
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534   171 DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTllnvqVIASGPMEEVFTPENLKRTYGE 249
Cdd:TIGR01257 2090 PLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLA-----IMVKGAFQCLGTIQHLKSKFGD 2163
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
19-214 1.44e-13

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 69.92  E-value: 1.44e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSlaqarkRIGYVPQRGSV 98
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENA------NIGYYAQDHAY 393
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  99 DWDFPTSVLDvvMMGLYGQlgwfkrpgPREREAALRcleqvSMQA---FTTRQISQ----LSGGQQQRVFLARALAQDAD 171
Cdd:PRK15064 394 DFENDLTLFD--WMSQWRQ--------EGDDEQAVR-----GTLGrllFSQDDIKKsvkvLSGGEKGRMLFGKLMMQKPN 458
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 172 LYFMDEPFAGVDAvteEAILRVLHELKKQGKTVVVVHHDLETV 214
Cdd:PRK15064 459 VLVMDEPTNHMDM---ESIESLNMALEKYEGTLIFVSHDREFV 498
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
19-243 1.64e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 69.47  E-value: 1.64e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   19 LRVRDLT---VVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVA-SGQVRFFGQSL-----AQA---- 85
Cdd:TIGR02633 258 LEARNLTcwdVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVdirnpAQAirag 337
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   86 -------RKRIGYVPQRGsVDWDFPTSVLDVvmmglYGQLGwfKRPGPREREAALRCLEQVSMQAFTTR-QISQLSGGQQ 157
Cdd:TIGR02633 338 iamvpedRKRHGIVPILG-VGKNITLSVLKS-----FCFKM--RIDAAAELQIIGSAIQRLKVKTASPFlPIGRLSGGNQ 409
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  158 QRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHltllnVQVIASGPMEEV 237
Cdd:TIGR02633 410 QKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDR-----VLVIGEGKLKGD 484

                  ....*.
gi 917519534  238 FTPENL 243
Cdd:TIGR02633 485 FVNHAL 490
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
18-251 3.64e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 68.73  E-value: 3.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ--------SLAQARKRI 89
Cdd:PRK10261 324 PLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQridtlspgKLQALRRDI 403
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQRGSVDWDFPTSVLDVVMMGLYGQlGWFKRPGPREREAALrcLEQVSMQA-FTTRQISQLSGGQQQRVFLARALAQ 168
Cdd:PRK10261 404 QFIFQDPYASLDPRQTVGDSIMEPLRVH-GLLPGKAAAARVAWL--LERVGLLPeHAWRYPHEFSGGQRQRICIARALAL 480
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 169 DADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFtpENLKRT 246
Cdd:PRK10261 481 NPKVIIADEAVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLgQIVEIGPRRAVF--ENPQHP 558

                 ....*
gi 917519534 247 YGERM 251
Cdd:PRK10261 559 YTRKL 563
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
19-210 4.99e-13

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 66.44  E-value: 4.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ------ARKRIGYV 92
Cdd:PRK11614   6 LSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwqtakiMREAVAIV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQrGSVDWDFPTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQVSMQAFTtrqisqLSGGQQQRVFLARALAQDADL 172
Cdd:PRK11614  86 PE-GRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPRLHERRIQRAGT------MSGGEQQMLAIGRALMSQPRL 158
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHD 210
Cdd:PRK11614 159 LLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQN 196
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
33-215 8.10e-13

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 64.65  E-value: 8.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGlvpvasgqvrffgqslAQARKRIGYVPQRGSvdwDFPTSVLD---- 108
Cdd:cd03238   10 NLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGLY----------------ASGKARLISFLPKFS---RNKLIFIDqlqf 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 109 VVMMGL-YGQLGwfkrpgprereaalrcleqvsmqafttRQISQLSGGQQQRVFLARALAQDAD--LYFMDEPFAGVDAV 185
Cdd:cd03238   71 LIDVGLgYLTLG---------------------------QKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQ 123
                        170       180       190
                 ....*....|....*....|....*....|
gi 917519534 186 TEEAILRVLHELKKQGKTVVVVHHDLETVR 215
Cdd:cd03238  124 DINQLLEVIKGLIDLGNTVILIEHNLDVLS 153
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
36-210 8.18e-13

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 67.45  E-value: 8.18e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRfFGQSLaqarkRIGYVPQ-RGSVD-----WDFPTSVLDV 109
Cdd:PRK11819 342 DLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIK-IGETV-----KLAYVDQsRDALDpnktvWEEISGGLDI 415
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 110 VMMGLY-----GQLGWFKRPGPrereaalrclEQvsmQafttRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDA 184
Cdd:PRK11819 416 IKVGNReipsrAYVGRFNFKGG----------DQ---Q----KKVGVLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDV 478
                        170       180
                 ....*....|....*....|....*..
gi 917519534 185 VTeeaiLRVLHE-LKKQGKTVVVVHHD 210
Cdd:PRK11819 479 ET----LRALEEaLLEFPGCAVVISHD 501
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
11-224 8.67e-13

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 67.76  E-value: 8.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   11 PESGASSPLRVRDLTVVYREKPA---LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSL-- 82
Cdd:TIGR00955  15 AQDGSWKQLVSRLRGCFCRERPRkhlLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPkgvKGSGSVLLNGMPIda 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   83 AQARKRIGYVPQrgsVDWDFPT-SVLDVVMMGLYGQLGwfKRPGPREREAALR-CLEQVSMQ-AFTTR-----QISQLSG 154
Cdd:TIGR00955  95 KEMRAISAYVQQ---DDLFIPTlTVREHLMFQAHLRMP--RRVTKKEKRERVDeVLQALGLRkCANTRigvpgRVKGLSG 169
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534  155 GQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVV-VHHDLETVRDYFDHLTLL 224
Cdd:TIGR00955 170 GERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICtIHQPSSELFELFDKIILM 240
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
19-210 1.04e-12

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 65.51  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA-----QARKRIGYVP 93
Cdd:PRK10247   8 LQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDIStlkpeIYRQQVSYCA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  94 QRGSVdwdFPTSVLDVVMmglygqLGWFKRPGPREREAALRCLEQVSM-QAFTTRQISQLSGGQQQRVFLARALAQDADL 172
Cdd:PRK10247  88 QTPTL---FGDTVYDNLI------FPWQIRNQQPDPAIFLDDLERFALpDTILTKNIAELSGGEKQRISLIRNLQFMPKV 158
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 917519534 173 YFMDEPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHHD 210
Cdd:PRK10247 159 LLLDEITSALDESNKHNVNEIIHRYvREQNIAVLWVTHD 197
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
40-238 1.28e-12

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 66.30  E-value: 1.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  40 EVPAGQLCAIVGPNGAGKSTLIKAVLGLVP----VASGQVRFFGQSLAQ--ARKRIGYVPQRGSVDWDFPTSVLD----- 108
Cdd:PRK11022  29 SVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRisEKERRNLVGAEVAMIFQDPMTSLNpcytv 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 109 --VVMMGLYGQLGWFKRpgpREREAALRCLEQVSMQAFTTR---QISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVD 183
Cdd:PRK11022 109 gfQIMEAIKVHQGGNKK---TRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALD 185
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 184 AVTEEAILRVLHEL-KKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVF 238
Cdd:PRK11022 186 VTIQAQIIELLLELqQKENMALVLITHDLALVAEAAHKIIVMYAgQVVETGKAHDIF 242
PLN03211 PLN03211
ABC transporter G-25; Provisional
18-225 1.34e-12

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 67.21  E-value: 1.34e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  18 PLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASgqvrFFGQSLAQARK-------RIG 90
Cdd:PLN03211  68 KPKISDETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNN----FTGTILANNRKptkqilkRTG 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRgsvDWDFPTsvLDVVMMGLYGQLgwFKRPGPREREAALRCLEQVSMQAFTTRQ---------ISQLSGGQQQRVF 161
Cdd:PLN03211 144 FVTQD---DILYPH--LTVRETLVFCSL--LRLPKSLTKQEKILVAESVISELGLTKCentiignsfIRGISGGERKRVS 216
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 162 LARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVV-VHHDLETVRDYFDHLTLLN 225
Cdd:PLN03211 217 IAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTsMHQPSSRVYQMFDSVLVLS 281
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
34-217 2.45e-12

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 64.94  E-value: 2.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLglVPVASgQVRFFGQSLAQARKRI---GYVPQRGSVDWDFP------- 103
Cdd:cd03271   11 LKNIDVDIPLGVLTCVTGVSGSGKSSLINDTL--YPALA-RRLHLKKEQPGNHDRIeglEHIDKVIVIDQSPIgrtprsn 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 104 -----------------------------------TSVLDVVMMGLYGQLGWFKRPgPREREAaLRCLEQVSMQAFTTRQ 148
Cdd:cd03271   88 patytgvfdeirelfcevckgkrynretlevrykgKSIADVLDMTVEEALEFFENI-PKIARK-LQTLCDVGLGYIKLGQ 165
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534 149 IS-QLSGGQQQRVFLARALAQDAD---LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR--DY 217
Cdd:cd03271  166 PAtTLSGGEAQRIKLAKELSKRSTgktLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNLDVIKcaDW 240
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
19-239 6.02e-12

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 64.44  E-value: 6.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYR--EKP--ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP----VASGQVRFFGQSLAQ--ARKR 88
Cdd:PRK15093   4 LDIRNLTIEFKtsDGWvkAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKdnwrVTADRMRFDDIDLLRlsPRER 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  89 IGYVPQRGSVDWDFPTSVLD-------VVMMGLYG---QLGWFKRPGPREREAaLRCLEQVSMQAFTTRQIS---QLSGG 155
Cdd:PRK15093  84 RKLVGHNVSMIFQEPQSCLDpservgrQLMQNIPGwtyKGRWWQRFGWRKRRA-IELLHRVGIKDHKDAMRSfpyELTEG 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 156 QQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGP 233
Cdd:PRK15093 163 ECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnNTTILLISHDLQMLSQWADKINVLYCgQTVETAP 242

                 ....*.
gi 917519534 234 MEEVFT 239
Cdd:PRK15093 243 SKELVT 248
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
40-217 6.37e-12

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 62.59  E-value: 6.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  40 EVPAGQLCAIVGPNGAGKSTLIKAVLGLVpvasgqvrffgqslaqarkrigyVPQRGSVDWDFPTSVLdvvmmglygqlg 119
Cdd:cd03222   21 VVKEGEVIGIVGPNGTGKTTAVKILAGQL-----------------------IPNGDNDEWDGITPVY------------ 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 120 wfkRPgprereaalrcleqvsmqafttrQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKK 199
Cdd:cd03222   66 ---KP-----------------------QYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSE 119
                        170
                 ....*....|....*....
gi 917519534 200 QG-KTVVVVHHDLeTVRDY 217
Cdd:cd03222  120 EGkKTALVVEHDL-AVLDY 137
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
19-212 6.47e-12

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 63.06  E-value: 6.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREkpalWDVDLE-VPAGQLCAIVGPNGAGKSTLIKAVlglvpvasgQVRFFGQSLAQARKR-----IGYV 92
Cdd:cd03279    6 LELKNFGPFREE----QVIDFTgLDNNGLFLICGPTGAGKSTILDAI---------TYALYGKTPRYGRQEnlrsvFAPG 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  93 PQRGSVDWDFptsvldvvmmglygQLGW-----FKRPGPRERE---AALrcLEQVSMQAFTTRQISQLSGGQQQRVFLAR 164
Cdd:cd03279   73 EDTAEVSFTF--------------QLGGkkyrvERSRGLDYDQftrIVL--LPQGEFDRFLARPVSTLSGGETFLASLSL 136
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 917519534 165 ALA-----QDA-----DLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:cd03279  137 ALAlsevlQNRggarlEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEE 194
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
19-215 8.21e-12

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 64.22  E-value: 8.21e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREK----------PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--- 85
Cdd:PRK11308   6 LQAIDLKKHYPVKrglfkperlvKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKAdpe 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 -----RKRIGYVPQRgsvdwdfPtsvldvvmmglYGQLGWFKRPG---------------PREREAALRCLEQVSMQA-F 144
Cdd:PRK11308  86 aqkllRQKIQIVFQN-------P-----------YGSLNPRKKVGqileepllintslsaAERREKALAMMAKVGLRPeH 147
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 917519534 145 TTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVR 215
Cdd:PRK11308 148 YDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSVVE 219
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
11-248 8.89e-12

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 64.97  E-value: 8.89e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    11 PESGAsspLRVRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA--- 85
Cdd:TIGR00957 1280 PPRGR---VEFRNYCLRYREdlDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIglh 1356
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    86 --RKRIGYVPQrgsvdwdfptsvlDVVMMGlyGQLGWFKRP-GPREREAALRCLEQVSMQAFTTRQISQL---------- 152
Cdd:TIGR00957 1357 dlRFKITIIPQ-------------DPVLFS--GSLRMNLDPfSQYSDEEVWWALELAHLKTFVSALPDKLdhecaeggen 1421
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   153 -SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHElKKQGKTVVVVHHDLETVRDYfdhltlLNVQVIAS 231
Cdd:TIGR00957 1422 lSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRT-QFEDCTVLTIAHRLNTIMDY------TRVIVLDK 1494
                          250
                   ....*....|....*..
gi 917519534   232 GPMEEVFTPENLKRTYG 248
Cdd:TIGR00957 1495 GEVAEFGAPSNLLQQRG 1511
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
49-222 2.03e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 63.60  E-value: 2.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  49 IVGPNGAGKSTLIKAVLGLVPVASGQVRffgqslAQARKRIGYVPQRGSVDwdfPT-SVLDVVMMGLygqlgwfkrpgpR 127
Cdd:PRK11819  38 VLGLNGAGKSTLLRIMAGVDKEFEGEAR------PAPGIKVGYLPQEPQLD---PEkTVRENVEEGV------------A 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 128 EREAALRCLEQVS---------MQAFTTRQ----------------------------------ISQLSGGQQQRVFLAR 164
Cdd:PRK11819  97 EVKAALDRFNEIYaayaepdadFDALAAEQgelqeiidaadawdldsqleiamdalrcppwdakVTKLSGGERRRVALCR 176
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 917519534 165 ALAQDADLYFMDEPFAGVDAvteEAILRVLHELKKQGKTVVVVHHDletvRdYF-DHLT 222
Cdd:PRK11819 177 LLLEKPDMLLLDEPTNHLDA---ESVAWLEQFLHDYPGTVVAVTHD----R-YFlDNVA 227
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
13-238 3.23e-11

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 62.43  E-value: 3.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  13 SGASSPLRVRDLTVVYREK----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSLAQA 85
Cdd:PRK09473   7 QQADALLDVKDLRVTFSTPdgdvTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAangRIGGSATFNGREILNL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  86 RKR---------IGYVPQrgsvdwDFPTSV----------LDVVMMglygqlgwFKRPGPRER-EAALRCLEQVSMQAFT 145
Cdd:PRK09473  87 PEKelnklraeqISMIFQ------DPMTSLnpymrvgeqlMEVLML--------HKGMSKAEAfEESVRMLDAVKMPEAR 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 146 TRQI---SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKT-VVVVHHDLETVRDYFDH- 220
Cdd:PRK09473 153 KRMKmypHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTaIIMITHDLGVVAGICDKv 232
                        250
                 ....*....|....*...
gi 917519534 221 LTLLNVQVIASGPMEEVF 238
Cdd:PRK09473 233 LVMYAGRTMEYGNARDVF 250
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
21-212 4.03e-11

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 63.01  E-value: 4.03e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    21 VRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPvASGQVRFFGQS-----LAQARKRIGYVP 93
Cdd:TIGR01271 1220 VQGLTAKYTEagRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSwnsvtLQTWRKAFGVIP 1298
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    94 QRgsvdwdfptsvldvvmmgLYGQLGWFKRP-GPRER---EAALRCLEQVSMQAFttrqISQ---------------LSG 154
Cdd:TIGR01271 1299 QK------------------VFIFSGTFRKNlDPYEQwsdEEIWKVAEEVGLKSV----IEQfpdkldfvlvdggyvLSN 1356
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917519534   155 GQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLhelkKQG---KTVVVVHHDLE 212
Cdd:TIGR01271 1357 GHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTL----KQSfsnCTVILSEHRVE 1413
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
19-220 5.54e-11

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 62.30  E-value: 5.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKP-ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAqARKRIGYVPQRGS 97
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVT-AEQPEDYRKLFSA 401
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  98 VDWDFPtsvLDVVMMGLYGQlgwfkrpgPREREAALRCLEQVSMQ---AFTTRQIS--QLSGGQQQRVFLARALAQDADL 172
Cdd:PRK10522 402 VFTDFH---LFDQLLGPEGK--------PANPALVEKWLERLKMAhklELEDGRISnlKLSKGQKKRLALLLALAEERDI 470
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 917519534 173 YFMDEPFAGVDAVTEEAILRV-LHELKKQGKTVVVVHHDletvrD-YFDH 220
Cdd:PRK10522 471 LLLDEWAADQDPHFRREFYQVlLPLLQEMGKTIFAISHD-----DhYFIH 515
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
12-238 6.15e-11

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 62.18  E-value: 6.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  12 ESGASSPLRVRDLTVVYREK----PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVR----------- 76
Cdd:PRK10261   6 ELDARDVLAVENLNIAFMQEqqkiAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQcdkmllrrrsr 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  77 ----FFGQSLAQARKRIG------YVPQRGSVDWDFPTSVLDVVMMGLYGQLGwfkrpgpRERE--AALRCLEQVSM--- 141
Cdd:PRK10261  86 qvieLSEQSAAQMRHVRGadmamiFQEPMTSLNPVFTVGEQIAESIRLHQGAS-------REEAmvEAKRMLDQVRIpea 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 142 QAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQ-GKTVVVVHHDLETVRDYFDH 220
Cdd:PRK10261 159 QTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEmSMGVIFITHDMGVVAEIADR 238
                        250
                 ....*....|....*....
gi 917519534 221 -LTLLNVQVIASGPMEEVF 238
Cdd:PRK10261 239 vLVMYQGEAVETGSVEQIF 257
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
29-225 7.45e-11

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 59.97  E-value: 7.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  29 REKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVA---SGQVRFFGQSLAQARKR----IGYVPQRgsvDWD 101
Cdd:cd03233   18 SKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKypgeIIYVSEE---DVH 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 102 FPTsvLDVvmmglygqlgwfkrpgpRER-EAALRCLeqvsmqafTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFA 180
Cdd:cd03233   95 FPT--LTV-----------------RETlDFALRCK--------GNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTR 147
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 917519534 181 GVDAVTEEAILRVLHELKKQGKTVVVV--HHDLETVRDYFDHLTLLN 225
Cdd:cd03233  148 GLDSSTALEILKCIRTMADVLKTTTFVslYQASDEIYDLFDKVLVLY 194
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
13-239 8.54e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 61.29  E-value: 8.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  13 SGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAG--KSTLIKAVLGlvPVASGQVRFFGQSLAQAR---K 87
Cdd:NF000106   8 NGARNAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G--PDAGRRPWRF*TWCANRRalrR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  88 RIG-YVPQRGSVDWDFpTSVLDVVMMGLYGQLgwfKRPGPREREAALrcLEQVSMQAFTTRQISQLSGGQQQRVFLARAL 166
Cdd:NF000106  86 TIG*HRPVR*GRRESF-SGRENLYMIGR*LDL---SRKDARARADEL--LERFSLTEAAGRAAAKYSGGMRRRLDLAASM 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 167 AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYFDHLTLLNV-QVIASGPMEEVFT 239
Cdd:NF000106 160 IGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRgRVIADGKVDELKT 233
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
19-214 2.13e-10

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 60.40  E-value: 2.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTvvyreKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSL---------------- 82
Cdd:PRK10762 258 LKVDNLS-----GPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVvtrspqdglangivyi 332
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  83 AQARKRIGYVpqrgsvdwdFPTSVLDvvMMGLYGqLGWFKRPGPREREAAlrclEQVSMQAFTT----------RQISQL 152
Cdd:PRK10762 333 SEDRKRDGLV---------LGMSVKE--NMSLTA-LRYFSRAGGSLKHAD----EQQAVSDFIRlfniktpsmeQAIGLL 396
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 917519534 153 SGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETV 214
Cdd:PRK10762 397 SGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEV 458
PLN03130 PLN03130
ABC transporter C family member; Provisional
11-243 2.63e-10

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 60.52  E-value: 2.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   11 PESGAsspLRVRDLTVVYREK--PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQ-------VRFFGqs 81
Cdd:PLN03130 1233 PSSGS---IKFEDVVLRYRPElpPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRilidgcdISKFG-- 1307
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   82 LAQARKRIGYVPQrgsvdwdfpTSVLdvvmmgLYGQLGWFKRPGPREREAAL-RCLEQVSMQAFTTR-------QISQ-- 151
Cdd:PLN03130 1308 LMDLRKVLGIIPQ---------APVL------FSGTVRFNLDPFNEHNDADLwESLERAHLKDVIRRnslgldaEVSEag 1372
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  152 --LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGkTVVVVHHDLETVRDYfDHLTLLNvqvi 229
Cdd:PLN03130 1373 enFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDALIQKTIREEFKSC-TMLIIAHRLNTIIDC-DRILVLD---- 1446
                         250
                  ....*....|....
gi 917519534  230 aSGPMEEVFTPENL 243
Cdd:PLN03130 1447 -AGRVVEFDTPENL 1459
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
44-216 2.88e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 57.38  E-value: 2.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    44 GQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGqslaqarkrigyvpqrgsvdwdfptsvldvvmmglygqlgwfkr 123
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYID-------------------------------------------- 37
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   124 pGPREREAALRCLEQVsmqaFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLH------EL 197
Cdd:smart00382  38 -GEDILEEVLDQLLLI----IVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrllllLK 112
                          170
                   ....*....|....*....
gi 917519534   198 KKQGKTVVVVHHDLETVRD 216
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGP 131
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
19-216 7.58e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 57.94  E-value: 7.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVaSGQVRFFGQS-----LAQARKRIGY 91
Cdd:cd03289    3 MTVKDLTAKYTEggNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNT-EGDIQIDGVSwnsvpLQKWRKAFGV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWDFPTSVLDVvmmglYGQlgWfkrpgprEREAALRCLEQVSMQAFTTRQISQ-----------LSGGQQQRV 160
Cdd:cd03289   82 IPQKVFIFSGTFRKNLDP-----YGK--W-------SDEEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLM 147
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 161 FLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHElKKQGKTVVVVHHDLETVRD 216
Cdd:cd03289  148 CLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQ-AFADCTVILSEHRIEAMLE 202
PLN03232 PLN03232
ABC transporter C family member; Provisional
11-243 1.09e-09

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 58.45  E-value: 1.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   11 PESG--ASSPLRVRDLTVVYREK--PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRF-------FG 79
Cdd:PLN03232 1225 PVSGwpSRGSIKFEDVHLRYRPGlpPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIddcdvakFG 1304
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   80 qsLAQARKRIGYVPQrgsvdwdfpTSVLdvvmmgLYGQLGWFKRPGPREREAAL-RCLEQVSMQAFTTR-------QISQ 151
Cdd:PLN03232 1305 --LTDLRRVLSIIPQ---------SPVL------FSGTVRFNIDPFSEHNDADLwEALERAHIKDVIDRnpfgldaEVSE 1367
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  152 ----LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGkTVVVVHHDLETVRDyfdhltLLNVQ 227
Cdd:PLN03232 1368 ggenFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQRTIREEFKSC-TMLVIAHRLNTIID------CDKIL 1440
                         250
                  ....*....|....*.
gi 917519534  228 VIASGPMEEVFTPENL 243
Cdd:PLN03232 1441 VLSSGQVLEYDSPQEL 1456
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
36-209 1.22e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 58.21  E-value: 1.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLA----QARKRIGYVPQRGSvdwdfptsvldvvm 111
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDagdiATRRRVGYMSQAFS-------------- 349
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 mgLYGQLG----------WFKRP----GPREREAALRC-LEQVsMQAFTtrqiSQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:NF033858 350 --LYGELTvrqnlelharLFHLPaaeiAARVAEMLERFdLADV-ADALP----DSLPLGIRQRLSLAVAVIHKPELLILD 422
                        170       180       190
                 ....*....|....*....|....*....|....
gi 917519534 177 EPFAGVDAVTEEAILRVLHEL-KKQGKTVVVVHH 209
Cdd:NF033858 423 EPTSGVDPVARDMFWRLLIELsREDGVTIFISTH 456
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
19-237 1.66e-09

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 56.72  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALW---------DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQArkRI 89
Cdd:PRK15112   5 LEVRNLSKTFRYRTGWFrrqtveavkPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFG--DY 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  90 GYVPQRGSVDWDFPTSVLDvvmmglygqlgwfkrpgPRER-----EAALRCLEQVSMQA------FTTRQIS-------- 150
Cdd:PRK15112  83 SYRSQRIRMIFQDPSTSLN-----------------PRQRisqilDFPLRLNTDLEPEQrekqiiETLRQVGllpdhasy 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 151 ---QLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK-KQGKTVVVVHHDLETVRDYFDH-LTLLN 225
Cdd:PRK15112 146 yphMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQeKQGISYIYVTQHLGMMKHISDQvLVMHQ 225
                        250
                 ....*....|..
gi 917519534 226 VQVIASGPMEEV 237
Cdd:PRK15112 226 GEVVERGSTADV 237
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
48-220 1.84e-09

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 56.08  E-value: 1.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  48 AIVGPNGAGKSTLIKAVLglvpVA-SGQVRFFGQSLAQARKRIGYVPQRGSVDWDFPT------------SVLDVVMMGL 114
Cdd:cd03240   26 LIVGQNGAGKTTIIEALK----YAlTGELPPNSKGGAHDPKLIREGEVRAQVKLAFENangkkytitrslAILENVIFCH 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 115 YGQLGWfkrPGPREREaalrcleqvsmqafttrqisQLSGGQQQ------RVFLARALAQDADLYFMDEPFAGVDAVT-E 187
Cdd:cd03240  102 QGESNW---PLLDMRG--------------------RCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENiE 158
                        170       180       190
                 ....*....|....*....|....*....|....
gi 917519534 188 EAILRVLHELKKQG-KTVVVVHHDlETVRDYFDH 220
Cdd:cd03240  159 ESLAEIIEERKSQKnFQLIVITHD-EELVDAADH 191
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
152-237 2.22e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 57.72  E-value: 2.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  152 LSGGQQQRVFLARALAQDAD---LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYfDHLTLLNV-- 226
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSKRSTgrtLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEHNLDVIKTA-DYIIDLGPeg 908
                          90
                  ....*....|....*.
gi 917519534  227 -----QVIASGPMEEV 237
Cdd:TIGR00630 909 gdgggTVVASGTPEEV 924
ycf16 CHL00131
sulfate ABC transporter protein; Validated
19-209 2.70e-09

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 56.19  E-value: 2.70e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG--LVPVASGQVRFFGQSL----AQARKRIG-- 90
Cdd:CHL00131   8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESIldlePEERAHLGif 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 ----Y---VPqrGSVDWDF------------------PTSVLDVVMmglygqlgwfkrpgprEReaalrcLEQVSMQA-F 144
Cdd:CHL00131  88 lafqYpieIP--GVSNADFlrlaynskrkfqglpeldPLEFLEIIN----------------EK------LKLVGMDPsF 143
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 145 TTRQISQ-LSGGQQQR-VFLARALAqDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHH 209
Cdd:CHL00131 144 LSRNVNEgFSGGEKKRnEILQMALL-DSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH 209
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
142-237 4.29e-09

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 56.57  E-value: 4.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 142 QAFTTrqisqLSGGQQQRVFLARALAQDAD---LYFMDEP-----FAGVDAVteeaiLRVLHELKKQGKTVVVVHHDLET 213
Cdd:COG0178  822 QPATT-----LSGGEAQRVKLASELSKRSTgktLYILDEPttglhFHDIRKL-----LEVLHRLVDKGNTVVVIEHNLDV 891
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 917519534 214 VR--DYfdhltllnV------------QVIASGPMEEV 237
Cdd:COG0178  892 IKtaDW--------IidlgpeggdgggEIVAEGTPEEV 921
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
32-178 5.22e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 56.11  E-value: 5.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  32 PALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFfGQSLAQARkrIGYVPQRgsvdwDFPTSVLDVVM 111
Cdd:PRK11147  17 PLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIY-EQDLIVAR--LQQDPPR-----NVEGTVYDFVA 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 112 MGLYGQLGWFKR-------PGPREREAALRCLEQVSMQ-------AFTTR--------------QISQLSGGQQQRVFLA 163
Cdd:PRK11147  89 EGIEEQAEYLKRyhdishlVETDPSEKNLNELAKLQEQldhhnlwQLENRinevlaqlgldpdaALSSLSGGWLRKAALG 168
                        170
                 ....*....|....*
gi 917519534 164 RALAQDADLYFMDEP 178
Cdd:PRK11147 169 RALVSNPDVLLLDEP 183
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
147-237 6.81e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 56.17  E-value: 6.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  147 RQISQLSGGQQQRVFLARALAQD--ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDYfDHLT-- 222
Cdd:TIGR00630 484 RAAGTLSGGEAQRIRLATQIGSGltGVLYVLDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEHDEDTIRAA-DYVIdi 562
                          90       100
                  ....*....|....*....|
gi 917519534  223 -----LLNVQVIASGPMEEV 237
Cdd:TIGR00630 563 gpgagEHGGEVVASGTPEEI 582
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
14-243 7.64e-09

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 54.91  E-value: 7.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  14 GASSPLRVRDLTVVYRE--KPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQA-----R 86
Cdd:cd03288   15 GLGGEIKIHDLCVRYENnlKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLplhtlR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  87 KRIGYVPQ-----RGSVDWDFP---TSVLDVVMMGL-YGQLGWFKRPGPRereaalrcleqvSMQAFTTRQISQLSGGQQ 157
Cdd:cd03288   95 SRLSIILQdpilfSGSIRFNLDpecKCTDDRLWEALeIAQLKNMVKSLPG------------GLDAVVTEGGENFSVGQR 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 158 QRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQgKTVVVVHHDLETVrdyfdhLTLLNVQVIASGPMEEV 237
Cdd:cd03288  163 QLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFAD-RTVVTIAHRVSTI------LDADLVLVLSRGILVEC 235

                 ....*.
gi 917519534 238 FTPENL 243
Cdd:cd03288  236 DTPENL 241
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
11-224 9.28e-09

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 55.56  E-value: 9.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  11 PESGASSPLRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVrffgqSLAQARKrIG 90
Cdd:PRK10636 305 PESLPNPLLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEI-----GLAKGIK-LG 378
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  91 YVPQRgsvdwdfptsvldvvmmglygQLGWFK----------RPGPREREAALR-CLEQVSMQA-FTTRQISQLSGGQQQ 158
Cdd:PRK10636 379 YFAQH---------------------QLEFLRadesplqhlaRLAPQELEQKLRdYLGGFGFQGdKVTEETRRFSGGEKA 437
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 159 RVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKkqgKTVVVVHHDLETVRDYFDHLTLL 224
Cdd:PRK10636 438 RLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFE---GALVVVSHDRHLLRSTTDDLYLV 500
uvrA PRK00349
excinuclease ABC subunit UvrA;
142-237 9.48e-09

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 55.46  E-value: 9.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 142 QAFTTrqisqLSGGQQQRVFLARALAQDAD---LYFMDEP-----FAGVDAvteeaILRVLHELKKQGKTVVVVHHDLET 213
Cdd:PRK00349 826 QPATT-----LSGGEAQRVKLAKELSKRSTgktLYILDEPttglhFEDIRK-----LLEVLHRLVDKGNTVVVIEHNLDV 895
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 917519534 214 VR--DYfdhltLLNV---------QVIASGPMEEV 237
Cdd:PRK00349 896 IKtaDW-----IIDLgpeggdgggEIVATGTPEEV 925
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
36-209 9.52e-09

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 55.53  E-value: 9.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVasgqvrfFGQSLAQARK-RIGYVPQR-----GSVDwD---FPTSV 106
Cdd:TIGR00954 470 SLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPV-------YGGRLTKPAKgKLFYVPQRpymtlGTLR-DqiiYPDSS 541
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  107 LDvvmmglygqlgwFKRPGPREREaALRCLEQVSMQAFTTRQIS---------QLSGGQQQRVFLARALAQDADLYFMDE 177
Cdd:TIGR00954 542 ED------------MKRRGLSDKD-LEQILDNVQLTHILEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFAILDE 608
                         170       180       190
                  ....*....|....*....|....*....|..
gi 917519534  178 PFAGVDAVTEEAILRVlheLKKQGKTVVVVHH 209
Cdd:TIGR00954 609 CTSAVSVDVEGYMYRL---CREFGITLFSVSH 637
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
33-217 1.58e-08

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 54.90  E-value: 1.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVpvasgqvrffgqslaqarkrigyVPQRGSVDWDfPTSVLDVVMM 112
Cdd:PRK13545  39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVT-----------------------MPNKGTVDIK-GSAALIAISS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 113 GLYGQL-------------GWFKRpgpREREAALRCLEQVSMQAFTTRQISQLSGGQQQRVFLARALAQDADLYFMDEPF 179
Cdd:PRK13545  95 GLNGQLtgienielkglmmGLTKE---KIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEAL 171
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 917519534 180 AGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:PRK13545 172 SVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSF 209
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
19-82 4.14e-08

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 52.49  E-value: 4.14e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534  19 LRVRDLTVVYREKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGL--VPVASGQVRFFGQSL 82
Cdd:PRK09580   2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDL 67
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
147-217 6.34e-08

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 53.29  E-value: 6.34e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534  147 RQISQLSGGQQQRVFLARAL---AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR--DY 217
Cdd:PRK00635  805 RPLSSLSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNMHVVKvaDY 880
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
34-253 6.52e-08

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 53.19  E-value: 6.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    34 LWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLG-----LVPVaSGQVRFFGQSLAQARKRI-GYVPQRGSVDWDFPtsVL 107
Cdd:TIGR00956   77 LKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASntdgfHIGV-EGVITYDGITPEEIKKHYrGDVVYNAETDVHFP--HL 153
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   108 DVvmmglyGQLGWF----KRPGPR----EREAALRCLEQVSMQAF---TTRQ-------ISQLSGGQQQRVFLARALAQD 169
Cdd:TIGR00956  154 TV------GETLDFaarcKTPQNRpdgvSREEYAKHIADVYMATYglsHTRNtkvgndfVRGVSGGERKRVSIAEASLGG 227
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   170 ADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV--HHDLETVRDYFDHLTLLNV-QVIASGPMEEVftpenlkRT 246
Cdd:TIGR00956  228 AKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVaiYQCSQDAYELFDKVIVLYEgYQIYFGPADKA-------KQ 300

                   ....*..
gi 917519534   247 YGERMRW 253
Cdd:TIGR00956  301 YFEKMGF 307
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
48-210 9.98e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 52.26  E-value: 9.98e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  48 AIVGPNGAGKSTLIKAVLGLVPVASGQVRfFGQSLaqarkRIGYVPQ-RGSVDWDfpTSVLDVVMMGlygqlgwfKRP-- 124
Cdd:PRK11147 349 ALIGPNGCGKTTLLKLMLGQLQADSGRIH-CGTKL-----EVAYFDQhRAELDPE--KTVMDNLAEG--------KQEvm 412
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 125 -GPREREaALRCLEQV---SMQAFTTrqISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTeeaiLRVLHEL--K 198
Cdd:PRK11147 413 vNGRPRH-VLGYLQDFlfhPKRAMTP--VKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVET----LELLEELldS 485
                        170
                 ....*....|..
gi 917519534 199 KQGkTVVVVHHD 210
Cdd:PRK11147 486 YQG-TVLLVSHD 496
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
147-243 2.33e-07

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 51.37  E-value: 2.33e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  147 RQISQLSGGQQQRVFLARALAqdADL----YFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDletvrdyfDHLT 222
Cdd:PRK00635  472 RALATLSGGEQERTALAKHLG--AELigitYILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHD--------EQMI 541
                          90       100
                  ....*....|....*....|.
gi 917519534  223 LLNVQVIASGPMEEVFTPENL 243
Cdd:PRK00635  542 SLADRIIDIGPGAGIFGGEVL 562
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
147-237 2.67e-07

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 51.18  E-value: 2.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 147 RQISQLSGGQQQRVFLARAL------AqdadLYFMDEPFAGV---DAvteEAILRVLHELKKQGKTVVVVHHDLETVR-- 215
Cdd:COG0178  481 RSAGTLSGGEAQRIRLATQIgsglvgV----LYVLDEPSIGLhqrDN---DRLIETLKRLRDLGNTVIVVEHDEDTIRaa 553
                         90       100       110
                 ....*....|....*....|....*....|.
gi 917519534 216 DYfdhltLLNV---------QVIASGPMEEV 237
Cdd:COG0178  554 DY-----IIDIgpgagehggEVVAQGTPEEI 579
PLN03140 PLN03140
ABC transporter G family member; Provisional
44-234 3.65e-07

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 51.00  E-value: 3.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   44 GQLCAIVGPNGAGKSTLIKAVLGLVP--VASGQVRFFGQSLAQAR-KRI-GYVPQRgsvdwDFPTSVLDVVMMGLYGqlG 119
Cdd:PLN03140  906 GVLTALMGVSGAGKTTLMDVLAGRKTggYIEGDIRISGFPKKQETfARIsGYCEQN-----DIHSPQVTVRESLIYS--A 978
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  120 WFKRPGPREREAALRCLEQVsMQAFTTRQ----------ISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEA 189
Cdd:PLN03140  979 FLRLPKEVSKEEKMMFVDEV-MELVELDNlkdaivglpgVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1057
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 917519534  190 ILRVLHELKKQGKTVV-VVHHDLETVRDYFDHLTLLNV--QVIASGPM 234
Cdd:PLN03140 1058 VMRTVRNTVDTGRTVVcTIHQPSIDIFEAFDELLLMKRggQVIYSGPL 1105
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
22-236 5.78e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 50.49  E-value: 5.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    22 RDLTV---VYREKPALWD-VDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVP---VASGQVRFFGQSL-AQARKRIGYVP 93
Cdd:TIGR00956  763 RNLTYevkIKKEKRVILNnVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTtgvITGGDRLVNGRPLdSSFQRSIGYVQ 842
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    94 QRgsvDWDFPTS-VLDVVMMGLYgqlgwFKRPGPREREAALRCLEQV----SMQAFTTRQI----SQLSGGQQQRVFLAR 164
Cdd:TIGR00956  843 QQ---DLHLPTStVRESLRFSAY-----LRQPKSVSKSEKMEYVEEVikllEMESYADAVVgvpgEGLNVEQRKRLTIGV 914
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534   165 AL-AQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVV-VVHHDLETVRDYFDHLTLLN--VQVIASGPMEE 236
Cdd:TIGR00956  915 ELvAKPKLLLFLDEPTSGLDSQTAWSICKLMRKLADHGQAILcTIHQPSAILFEEFDRLLLLQkgGQTVYFGDLGE 990
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
19-207 6.61e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 49.73  E-value: 6.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  19 LRVRDLTVVyrEKPALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQSLAQ--ARKRI--GY--- 91
Cdd:PRK10982 251 LEVRNLTSL--RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNhnANEAInhGFalv 328
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  92 VPQRGSVDWdfpTSVLDVVMMGLYGQLGWFKRPGPREREAALRCLEQV---SMQAFTTRQ---ISQLSGGQQQRVFLARA 165
Cdd:PRK10982 329 TEERRSTGI---YAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWvidSMRVKTPGHrtqIGSLSGGNQQKVIIGRW 405
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 917519534 166 LAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV 207
Cdd:PRK10982 406 LLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIII 447
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
150-215 8.79e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 49.64  E-value: 8.79e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534  150 SQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK-KQGKTVVVVHHDLETVR 215
Cdd:PTZ00265  578 SKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKgNENRITIIIAHRLSTIR 644
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
152-215 1.09e-06

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 49.64  E-value: 1.09e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534  152 LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELK-KQGKTVVVVHHDLETVR 215
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKdKADKTIITIAHRIASIK 1423
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
33-217 1.30e-06

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 48.27  E-value: 1.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  33 ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQslaqarkrigyvpqrgsvdwdfpTSVLdVVMM 112
Cdd:PRK13546  39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE-----------------------VSVI-AISA 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 113 GLYGQLgwfkrPGPREREAALRCLeqvsmqAFTTRQISQL---------------------SGGQQQRVFLARALAQDAD 171
Cdd:PRK13546  95 GLSGQL-----TGIENIEFKMLCM------GFKRKEIKAMtpkiiefselgefiyqpvkkySSGMRAKLGFSINITVNPD 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 917519534 172 LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVRDY 217
Cdd:PRK13546 164 ILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQF 209
PLN03073 PLN03073
ABC transporter F family; Provisional
48-221 7.56e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 46.78  E-value: 7.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  48 AIVGPNGAGKSTLIKAVLGLVPVASGQVrffgqsLAQARKRIGYVPQRGSVDWDFPTSVLdVVMMGLYgqlgwfkrPGPR 127
Cdd:PLN03073 539 AMVGPNGIGKSTILKLISGELQPSSGTV------FRSAKVRMAVFSQHHVDGLDLSSNPL-LYMMRCF--------PGVP 603
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 128 ERE-----AALRCLEQVSMQAFTTrqisqLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLheLKKQGK 202
Cdd:PLN03073 604 EQKlrahlGSFGVTGNLALQPMYT-----LSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGL--VLFQGG 676
                        170
                 ....*....|....*....
gi 917519534 203 tVVVVHHDLETVRDYFDHL 221
Cdd:PLN03073 677 -VLMVSHDEHLISGSVDEL 694
PTZ00243 PTZ00243
ABC transporter; Provisional
3-217 1.04e-05

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 46.31  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534    3 TQPKTVQhpesgASSpLRVRDLTVVYREK-P-ALWDVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ 80
Cdd:PTZ00243 1299 AAPHPVQ-----AGS-LVFEGVQMRYREGlPlVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGR 1372
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   81 -----SLAQARKRIGYVPQ---------RGSVDWDFPTSVLDVvmmglygqlgW--FKRPGPREREAAlrclEQVSMQAF 144
Cdd:PTZ00243 1373 eigayGLRELRRQFSMIPQdpvlfdgtvRQNVDPFLEASSAEV----------WaaLELVGLRERVAS----ESEGIDSR 1438
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  145 TTRQISQLSGGQQQRVFLARA-LAQDADLYFMDEPFAGVDavteeailrvlHELKKQ----------GKTVVVVHHDLET 213
Cdd:PTZ00243 1439 VLEGGSNYSVGQRQLMCMARAlLKKGSGFILMDEATANID-----------PALDRQiqatvmsafsAYTVITIAHRLHT 1507

                  ....
gi 917519534  214 VRDY 217
Cdd:PTZ00243 1508 VAQY 1511
GguA NF040905
sugar ABC transporter ATP-binding protein;
152-207 1.11e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.94  E-value: 1.11e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534 152 LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVV 207
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVI 460
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
28-211 1.70e-05

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 44.62  E-value: 1.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  28 YREKpalWDVDLEvpaGQLCAIVGPNGAGKSTLIKAV-LGLvpvasgqvrfFGQSLAQARKRIGYVPqRGSVDwdfpTSV 106
Cdd:COG0419   13 YRDT---ETIDFD---DGLNLIVGPNGAGKSTILEAIrYAL----------YGKARSRSKLRSDLIN-VGSEE----ASV 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 107 -LDVVMMG-LY------GQLGWFKRPGPREREAALR---------------------------------CLEQVSMQAFT 145
Cdd:COG0419   72 eLEFEHGGkRYrierrqGEFAEFLEAKPSERKEALKrllgleiyeelkerlkeleealesaleelaelqKLKQEILAQLS 151
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534 146 T-RQISQLSGGQQqrvfLARALAQDADLyFMDepFAGVDAVTEEAILRVLHELKkqgktvvVVHHDL 211
Cdd:COG0419  152 GlDPIETLSGGER----LRLALADLLSL-ILD--FGSLDEERLERLLDALEELA-------IITHVI 204
COG4637 COG4637
Predicted ATPase [General function prediction only];
38-63 2.62e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 44.92  E-value: 2.62e-05
                         10        20
                 ....*....|....*....|....*.
gi 917519534  38 DLEVPAGQLCAIVGPNGAGKSTLIKA 63
Cdd:COG4637   15 DLELPLGPLTVLIGANGSGKSNLLDA 40
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
44-219 5.57e-05

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 44.01  E-value: 5.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  44 GQLCAIVGPNGAGKSTLIKAVLGLVPVASGQVRFFGQ-SLAqarkrigYVPQRGSVdwdFPTSVLDVVMMG--------- 113
Cdd:PRK10636  27 GQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwQLA-------WVNQETPA---LPQPALEYVIDGdreyrqlea 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 114 ----------------LYGQLGWFKRPGPREREAALrcLEQVSM-QAFTTRQISQLSGGQQQRVFLARALAQDADLYFMD 176
Cdd:PRK10636  97 qlhdanerndghaiatIHGKLDAIDAWTIRSRAASL--LHGLGFsNEQLERPVSDFSGGWRMRLNLAQALICRSDLLLLD 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 917519534 177 EPFAGVDAvteEAILRVLHELKKQGKTVVVVHHDletvRDYFD 219
Cdd:PRK10636 175 EPTNHLDL---DAVIWLEKWLKSYQGTLILISHD----RDFLD 210
uvrA PRK00349
excinuclease ABC subunit UvrA;
152-237 8.15e-05

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 43.52  E-value: 8.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 152 LSGGQQQRVFLAralAQDAD-----LYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHHDLETVR--DYfdhltLL 224
Cdd:PRK00349 490 LSGGEAQRIRLA---TQIGSgltgvLYVLDEPSIGLHQRDNDRLIETLKHLRDLGNTLIVVEHDEDTIRaaDY-----IV 561
                         90       100
                 ....*....|....*....|..
gi 917519534 225 NV---------QVIASGPMEEV 237
Cdd:PRK00349 562 DIgpgagvhggEVVASGTPEEI 583
AAA_29 pfam13555
P-loop containing region of AAA domain;
36-77 1.22e-04

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 39.12  E-value: 1.22e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 917519534   36 DVDLEVPAGQLCAIVGPNGAGKSTLIKAVLGLVpVASGQVRF 77
Cdd:pfam13555  14 GHTIPIDPRGNTLLTGPSGSGKSTLLDAIQTLL-VPAKRARF 54
PLN03073 PLN03073
ABC transporter F family; Provisional
141-212 1.90e-04

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 42.54  E-value: 1.90e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 917519534 141 MQaftTRQISQLSGGQQQRVFLARALAQDADLYFMDEPFAGVDAvteEAILRVLHELKKQGKTVVVVHHDLE 212
Cdd:PLN03073 337 MQ---VKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDL---HAVLWLETYLLKWPKTFIVVSHARE 402
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
50-210 6.00e-04

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 40.65  E-value: 6.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  50 VGPNGAGKSTLIKaVLG--LVPvASGQVrffgqSLaQARKRIGYVPQRGSVDWDFptSVLDVVMMGlYGQLGWFKrpgpR 127
Cdd:PRK15064  33 IGANGCGKSTFMK-ILGgdLEP-SAGNV-----SL-DPNERLGKLRQDQFAFEEF--TVLDTVIMG-HTELWEVK----Q 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534 128 EREA-----------ALRC--LEQV--SMQAFT---------------TRQ----ISQLSGGQQQRVFLARALAQDADLY 173
Cdd:PRK15064  98 ERDRiyalpemseedGMKVadLEVKfaEMDGYTaearagelllgvgipEEQhyglMSEVAPGWKLRVLLAQALFSNPDIL 177
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 917519534 174 FMDEPFAGVDAVTeeaiLRVL-HELKKQGKTVVVVHHD 210
Cdd:PRK15064 178 LLDEPTNNLDINT----IRWLeDVLNERNSTMIIISHD 211
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
139-225 8.20e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 40.72  E-value: 8.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534   139 VSMQAFTTRQISQLSGGQQQRVFLARALA----------QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVH 208
Cdd:TIGR00618  938 ADAYTGSVRPSATLSGGETFLASLSLALAladllstsggTVLDSLFIDEGFGSLDEDSLDRAIGILDAIREGSKMIGIIS 1017
                           90
                   ....*....|....*..
gi 917519534   209 HdLETVRDYFDHLTLLN 225
Cdd:TIGR00618 1018 H-VPEFRERIPHRILVK 1033
COG4938 COG4938
Predicted ATPase [General function prediction only];
38-67 9.67e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443965 [Multi-domain]  Cd Length: 277  Bit Score: 39.57  E-value: 9.67e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 917519534  38 DLEVPAGQLCAIVGPNGAGKSTLIKAVLGL 67
Cdd:COG4938   14 EAELELKPLTLLIGPNGSGKSTLIQALLLL 43
ABC_SMC_barmotin cd03278
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ...
37-67 1.00e-03

ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213245 [Multi-domain]  Cd Length: 197  Bit Score: 38.99  E-value: 1.00e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 917519534  37 VDLEVPAGqLCAIVGPNGAGKSTLIKA---VLGL 67
Cdd:cd03278   16 TTIPFPPG-LTAIVGPNGSGKSNIIDAirwVLGE 48
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
142-209 1.13e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 40.17  E-value: 1.13e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 917519534  142 QAFTTRQISQLSGGQQQRVFLARALA--------QDADLYFMDEPFAGVDAVTEEAILRVLHELKKQGKTVVVVHH 209
Cdd:PRK10246  940 QADAVRDTRTLSGGESFLVSLALALAlsdlvshkTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISH 1015
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
145-196 1.60e-03

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 36.83  E-value: 1.60e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917519534  145 TTRQISQLSGGQQQRVF---LARALAQ---DAD-------LYFMDEPFAGVDAVTEEAILRVLHE 196
Cdd:pfam13558  26 TYRRSGGLSGGEKQLLAylpLAAALAAqygSAEgrppaprLVFLDEAFAKLDEENIRTALELLRA 90
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
36-91 1.94e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 38.83  E-value: 1.94e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 917519534  36 DVDLEVPAGqLCAIVGPNGAGKSTLIKA-VLGLVPVASGQVRFFGQSLAQARKRIGY 91
Cdd:COG3950   18 EIDFDNPPR-LTVLVGENGSGKTTLLEAiALALSGLLSRLDDVKFRKLLIRNGEFGD 73
ABC_SMC3_euk cd03272
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ...
141-200 2.07e-03

ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213239 [Multi-domain]  Cd Length: 243  Bit Score: 38.40  E-value: 2.07e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917519534 141 MQAFTTRQISQLSGGQQQRVFLARALA-QDAD---LYFMDEPFAGVDAVTEEAILRVLHELKKQ 200
Cdd:cd03272  148 MKQDEQQEMQQLSGGQKSLVALALIFAiQKCDpapFYLFDEIDAALDAQYRTAVANMIKELSDG 211
PLN03140 PLN03140
ABC transporter G family member; Provisional
152-239 2.30e-03

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 39.06  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917519534  152 LSGGQQQRVFLARALAQDADLYFMDEPFAGVDAVTEEAILRVLHElkkqgktvvVVHHDLETVR-----------DYFDH 220
Cdd:PLN03140  337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQ---------IVHLTEATVLmsllqpapetfDLFDD 407
                          90       100
                  ....*....|....*....|
gi 917519534  221 LTLLNV-QVIASGPMEEVFT 239
Cdd:PLN03140  408 IILLSEgQIVYQGPRDHILE 427
AAA_23 pfam13476
AAA domain;
49-64 3.47e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 37.48  E-value: 3.47e-03
                          10
                  ....*....|....*.
gi 917519534   49 IVGPNGAGKSTLIKAV 64
Cdd:pfam13476  23 ITGPNGSGKTTILDAI 38
YjeQ_EngC cd01854
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ...
43-66 3.63e-03

Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.


Pssm-ID: 206747 [Multi-domain]  Cd Length: 211  Bit Score: 37.76  E-value: 3.63e-03
                         10        20
                 ....*....|....*....|....
gi 917519534  43 AGQLCAIVGPNGAGKSTLIKAVLG 66
Cdd:cd01854   84 KGKTSVLVGQSGVGKSTLLNALLP 107
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
48-67 4.42e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 37.75  E-value: 4.42e-03
                          10        20
                  ....*....|....*....|
gi 917519534   48 AIVGPNGAGKSTLIKAVLGL 67
Cdd:pfam13304   3 VLIGPNGSGKSNLLEALRFL 22
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
38-63 4.71e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 37.67  E-value: 4.71e-03
                         10        20
                 ....*....|....*....|....*..
gi 917519534  38 DLEVP-AGQLCAIVGPNGAGKSTLIKA 63
Cdd:COG3593   16 DLSIElSDDLTVLVGENNSGKSSILEA 42
COG1106 COG1106
ATPase/GTPase, AAA15 family [General function prediction only];
48-64 7.59e-03

ATPase/GTPase, AAA15 family [General function prediction only];


Pssm-ID: 440723 [Multi-domain]  Cd Length: 330  Bit Score: 36.95  E-value: 7.59e-03
                         10
                 ....*....|....*..
gi 917519534  48 AIVGPNGAGKSTLIKAV 64
Cdd:COG1106   33 LIYGANASGKSNLLEAL 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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