|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-782 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1545.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMIGNLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWIMETPLQPALEAAIREAWAEMESRYGQgLAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVF 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGE-ASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 161 ASLYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLF 240
Cdd:PRK06464 162 ASLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 241 KPNLEAGKPAVLRRSLGSKATRMVYAEGS--GVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGE 318
Cdd:PRK06464 242 KPTLKAGKPAIVRRTLGSKKIKMVYDDGGehGVKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDGD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 319 SGQLFILQARPETVKSR-SGQAMERFKLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGDVLVTDMTDPDWEPI 397
Cdd:PRK06464 322 DGKLYIVQARPETVKSRkEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEPV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 398 MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVACSEGDTGRIYKGKLAFSVAEDTLDEMPPAPL 477
Cdd:PRK06464 402 MKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETPT 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 478 KIMMNVANADRAFDFAQIPNHGIGLARLEFIINRMIGIHPRALLEYSKQNEEVRAEIDRRIAGYADPVSFYVDKLAEGIA 557
Cdd:PRK06464 482 KIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGIA 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 558 TIAAPFAPNPVIVRLSDFKSNEYANLIGGEQYEPEEENPMIGWRGASRYVDESFKPAFELECRALKKVRETMGLSHVWAM 637
Cdd:PRK06464 562 TVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEVM 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 638 IPFVRTVDEARDVVEVLEGFGLKRGEQGLKLIMMCELPSNALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSALVAHRFD 717
Cdd:PRK06464 642 IPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFD 721
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906867083 718 ERNDAVKALLSMAIKACRDRGKYIGICGQGPSDYPDLAQWLLDQGIESMSLNPDTVVDTWRMLAS 782
Cdd:PRK06464 722 ERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-782 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1262.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 4 YILWLDELGMADLDKVGGKNSSLGEMIGNLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALAATG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 84 RQIRDWIMETPLQPALEAAIREAWAEMESRYGQGLA-VAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVFAS 162
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEDYGKEEAdVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 163 LYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLFKP 242
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 243 NLEAGKPAVLRRSLGSKATRMVYAE---GSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGES 319
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPdggGVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGFD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 320 GQLFILQARPETVKSR--SGQAMERFKLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGDVLVTDMTDPDWEPI 397
Cdd:TIGR01418 321 GEIFIVQARPETVQSRkkKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 398 MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVACSEGDTGRIYKGKLAFSVAEDTLDEMPPAPL 477
Cdd:TIGR01418 401 MKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTAT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 478 KIMMNVANADRAFDFAQIPNHGIGLARLEFIINRMIGIHPRALLEYSKQNEEVRAEIDRRIAGyaDPVSFYVDKLAEGIA 557
Cdd:TIGR01418 481 KIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGIA 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 558 TIAAPFAPNPVIVRLSDFKSNEYANLIGGEQYEPEEENPMIGWRGASRYVDESFKPAFELECRALKKVRETMGLSHVWAM 637
Cdd:TIGR01418 559 KVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEVM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 638 IPFVRTVDEARDVVEVLEGFGLKRGEQGLKLIMMCELPSNALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSALVAHRFD 717
Cdd:TIGR01418 639 IPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLFD 718
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906867083 718 ERNDAVKALLSMAIKACRDRGKYIGICGQGPSDYPDLAQWLLDQGIESMSLNPDTVVDTWRMLAS 782
Cdd:TIGR01418 719 ERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-455 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 665.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMIGnlsgLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWIMETPLQPALEAAIREAWAEMESRYGQGLAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVF 160
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKFGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 161 ASLYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLF 240
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 241 KPNleagkpaVLRRSLGSKATRMVYaeGSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDgeSG 320
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVY--DGGTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID--DG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 321 QLFILQARPETVKSR--SGQAMERF---------------KLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGD 383
Cdd:COG0574 306 KLYILQTRPITVLEGliTKEALLRVdpaqldqllhprfdpKAKEEGEVLAKGLPASPGAASGKVVFIADEAELARFQEGV 385
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 906867083 384 VLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVacsEGDTGRI 455
Cdd:COG0574 386 ILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
19-347 |
2.08e-157 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 460.52 E-value: 2.08e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 19 VGGKNSSLGEMignLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALAATGRQIRDWIMETPLQPA 98
Cdd:pfam01326 4 VGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPLPEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 99 LEAAIREAWAEMESRYGQG-LAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVFASLYNDRAIAYRVHHGF 177
Cdd:pfam01326 81 LEEAIREAYEELGKKFGDEpLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRREKGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 178 DHHDVALSAGIQLMVRsgSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLFKPNLEagkpaVLRRSLG 257
Cdd:pfam01326 161 DHEDVALAVGVQRMVR--SDASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRRTIG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 258 SKATRMVYAE-GSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGESGQLFILQARPETVKSR- 335
Cdd:pfam01326 234 EKEIKMVYDEgGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPETVWSEa 313
|
330
....*....|...
gi 906867083 336 -SGQAMERFKLEE 347
Cdd:pfam01326 314 mEKIAAEILEEGL 326
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-782 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1545.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMIGNLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWIMETPLQPALEAAIREAWAEMESRYGQgLAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVF 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKLSAGYGE-ASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 161 ASLYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLF 240
Cdd:PRK06464 162 ASLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 241 KPNLEAGKPAVLRRSLGSKATRMVYAEGS--GVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGE 318
Cdd:PRK06464 242 KPTLKAGKPAIVRRTLGSKKIKMVYDDGGehGVKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKDGD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 319 SGQLFILQARPETVKSR-SGQAMERFKLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGDVLVTDMTDPDWEPI 397
Cdd:PRK06464 322 DGKLYIVQARPETVKSRkEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWEPV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 398 MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVACSEGDTGRIYKGKLAFSVAEDTLDEMPPAPL 477
Cdd:PRK06464 402 MKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPETPT 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 478 KIMMNVANADRAFDFAQIPNHGIGLARLEFIINRMIGIHPRALLEYSKQNEEVRAEIDRRIAGYADPVSFYVDKLAEGIA 557
Cdd:PRK06464 482 KIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEGIA 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 558 TIAAPFAPNPVIVRLSDFKSNEYANLIGGEQYEPEEENPMIGWRGASRYVDESFKPAFELECRALKKVRETMGLSHVWAM 637
Cdd:PRK06464 562 TVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVEVM 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 638 IPFVRTVDEARDVVEVLEGFGLKRGEQGLKLIMMCELPSNALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSALVAHRFD 717
Cdd:PRK06464 642 IPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHLFD 721
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906867083 718 ERNDAVKALLSMAIKACRDRGKYIGICGQGPSDYPDLAQWLLDQGIESMSLNPDTVVDTWRMLAS 782
Cdd:PRK06464 722 ERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-782 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1262.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 4 YILWLDELGMADLDKVGGKNSSLGEMIGNLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALAATG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 84 RQIRDWIMETPLQPALEAAIREAWAEMESRYGQGLA-VAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVFAS 162
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLSEDYGKEEAdVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 163 LYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLFKP 242
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 243 NLEAGKPAVLRRSLGSKATRMVYAE---GSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGES 319
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPdggGVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGFD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 320 GQLFILQARPETVKSR--SGQAMERFKLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGDVLVTDMTDPDWEPI 397
Cdd:TIGR01418 321 GEIFIVQARPETVQSRkkKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEPA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 398 MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVACSEGDTGRIYKGKLAFSVAEDTLDEMPPAPL 477
Cdd:TIGR01418 401 MKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTAT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 478 KIMMNVANADRAFDFAQIPNHGIGLARLEFIINRMIGIHPRALLEYSKQNEEVRAEIDRRIAGyaDPVSFYVDKLAEGIA 557
Cdd:TIGR01418 481 KIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGIA 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 558 TIAAPFAPNPVIVRLSDFKSNEYANLIGGEQYEPEEENPMIGWRGASRYVDESFKPAFELECRALKKVRETMGLSHVWAM 637
Cdd:TIGR01418 559 KVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEVM 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 638 IPFVRTVDEARDVVEVLEGFGLKRGEQGLKLIMMCELPSNALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSALVAHRFD 717
Cdd:TIGR01418 639 IPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLFD 718
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906867083 718 ERNDAVKALLSMAIKACRDRGKYIGICGQGPSDYPDLAQWLLDQGIESMSLNPDTVVDTWRMLAS 782
Cdd:TIGR01418 719 ERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-455 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 665.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMIGnlsgLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMTR----LGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWIMETPLQPALEAAIREAWAEMESRYGQGLAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVF 160
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKFGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 161 ASLYNDRAIAYRVHHGFDHHDVALSAGIQLMVRSGSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLF 240
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 241 KPNleagkpaVLRRSLGSKATRMVYaeGSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDgeSG 320
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVY--DGGTVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID--DG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 321 QLFILQARPETVKSR--SGQAMERF---------------KLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGD 383
Cdd:COG0574 306 KLYILQTRPITVLEGliTKEALLRVdpaqldqllhprfdpKAKEEGEVLAKGLPASPGAASGKVVFIADEAELARFQEGV 385
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 906867083 384 VLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVacsEGDTGRI 455
Cdd:COG0574 386 ILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
19-347 |
2.08e-157 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 460.52 E-value: 2.08e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 19 VGGKNSSLGEMignLSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALAATGRQIRDWIMETPLQPA 98
Cdd:pfam01326 4 VGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPLPEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 99 LEAAIREAWAEMESRYGQG-LAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVFASLYNDRAIAYRVHHGF 177
Cdd:pfam01326 81 LEEAIREAYEELGKKFGDEpLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYRREKGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 178 DHHDVALSAGIQLMVRsgSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLFKPNLEagkpaVLRRSLG 257
Cdd:pfam01326 161 DHEDVALAVGVQRMVR--SDASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTLE-----ILRRTIG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 258 SKATRMVYAE-GSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGESGQLFILQARPETVKSR- 335
Cdd:pfam01326 234 EKEIKMVYDEgGEGTKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQARPETVWSEa 313
|
330
....*....|...
gi 906867083 336 -SGQAMERFKLEE 347
Cdd:pfam01326 314 mEKIAAEILEEGL 326
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-331 |
4.73e-100 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 329.16 E-value: 4.73e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMignlSGLGVSVPGGFATTADAFREFLDQSGLAGRIQDALEHLDAEDTRALA 80
Cdd:PRK06241 1 MSSYVLDFQEIDKTQLPLVGGKGANLGEL----SRAGIPVPEGFCVTTEAYKKFLEQNEEFDALLDQLSALKLEDREQIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWIMETPLQPALEAAIREAWaemeSRYGQGLAVAVRSSATAEDLPDASFAGQQETFLNVRGLDEVLEKLHAVF 160
Cdd:PRK06241 77 EISAKIREVIEAIEIPEDIVEAIAAAL----SKFGEDHAYAVRSSATAEDLPTASFAGQQDTYLNVIGKDAILQHIRKCW 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 161 ASLYNDRAIAYRVHHGFDHHDVALSAGIQLMVRsgSGASGVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPDEFYLf 240
Cdd:PRK06241 153 ASLFTERAVIYRIQNGFDHRKVYMSVVVQKMVF--PEASGIMFTADPVTGNRKVLSIDASFGLGEALVSGLVSADTYKV- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 241 kpnleaGKPAVLRRSLGSKATRMVYAEGSGVLTEDTPEALRNRFSISDDDATRLAEMALTIEKHYGRPMDIEWGKDGesG 320
Cdd:PRK06241 230 ------REGKIIDKTIATKKLAIYALKEGGTETKEIEPEQQKSQTLTDEQILELARLGRKIEAHFGCPQDIEWCLAD--G 301
|
330
....*....|.
gi 906867083 321 QLFILQARPET 331
Cdd:PRK06241 302 TFYILQSRPIT 312
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
477-784 |
3.29e-60 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 205.62 E-value: 3.29e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 477 LKIMMNVANADRAFDFAQIPNHGIGLARLEFIINrmigihpralleyskqneevraEIDRRIagyadpvsfYVDKLAEGI 556
Cdd:pfam02896 20 IKVAANIGTPDDAEAALANGAEGIGLYRTEFLFM----------------------DRDELP---------TEDEQFEAY 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 557 ATIAAPFAPNPVIVRLSDFKSNEYanLIGGEqyEPEEENPMIGWRGASRYVDEsfKPAFELECRALKKVRETMglsHVWA 636
Cdd:pfam02896 69 KGVLEAMNGRPVTVRTLDIGGDKE--LPYLE--EPEEMNPFLGWRGIRIGLDR--PELFRTQLRAILRASAFG---NLRI 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 637 MIPFVRTVDEARDVVEVLEGFGLKRGEQ-----GLKLIMMCELPSNALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSAL 711
Cdd:pfam02896 140 MFPMVASVEELREAKAIIEEVKEELDAEvgfdkDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNER 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 906867083 712 VAHRFDERNDAVKALLSMAIKACRDRGKYIGICGQGPSDyPDLAQWLLDQGIESMSLNPDTVVDTWRMLASSD 784
Cdd:pfam02896 220 VAYLYDPLHPAVLRLIKEVIRAAHRHGKWVGICGEMAGD-PSAVPLLVGLGLDEFSMSPDSVPRARALLAQID 291
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
338-770 |
1.60e-42 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 163.32 E-value: 1.60e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 338 QAMERF--KLEETGD-VLAEgRA-----IGQRIG---TGVARV-IESLDE-----MHDVAPGDVLvtdMTDPdwepimKR 400
Cdd:COG1080 105 EVIEELaaQFEALDDeYLRE-RAadirdVGRRVLrnlLGVEAPdLSDLPEpvilvAHDLTPSDTA---QLDP------SR 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 401 AAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVacsEGDTGRI-----------YKGKLA-FSVAEDT 468
Cdd:COG1080 175 VAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIV---DGDAGVVivnpdeetlaeYRERQAeYAAERAE 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 469 LDEMPPAP--------LKIMMNVANADrafDFAQIPNH---GIGLARLEFI-INRmiGIHPralleyskqNEEVRAEIDR 536
Cdd:COG1080 252 LARLRDLPavtldgvrVELAANIGLPE---DAAAALENgaeGVGLFRTEFLfMDR--DDLP---------TEEEQFEAYR 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 537 RIAgyadpvsfyvdklaEGiatiaapFAPNPVIVRLSDfksneyanlIGGE-----QYEPEEENPMIGWRGASRYVDEsf 611
Cdd:COG1080 318 AVA--------------EA-------MGGRPVTIRTLD---------IGGDkplpyLPLPKEENPFLGLRAIRLCLDR-- 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 612 kPA-FELECRAL------KKVRetmglshvwAMIPFVRTVDE---ARDVVEV----LEGFGLKRGEQgLKLIMMCELPSN 677
Cdd:COG1080 366 -PElFRTQLRAIlrasahGNLR---------IMFPMISSVEElrqAKALLEEakaeLRAEGIPFDED-IPVGIMIEVPAA 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 678 ALLADQFLEHFDGFSIGSNDMTQLTLGLDRDSALVAHRFDERNDAVKALLSMAIKACRDRGKYIGICGQGPSDyPDLAQW 757
Cdd:COG1080 435 ALIADQLAKEVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGD-PLATPL 513
|
490
....*....|...
gi 906867083 758 LLDQGIESMSLNP 770
Cdd:COG1080 514 LLGLGLDELSMSP 526
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
349-458 |
1.54e-34 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 134.26 E-value: 1.54e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 349 GDVLAEGRAIGQRIGTGVARVIESLDE-MHDVAPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAV 427
Cdd:COG3848 209 GDVLAKGQGIGRGSVTGKAVVARSAEEaLEKFEEGDILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVI 288
|
90 100 110
....*....|....*....|....*....|.
gi 906867083 428 VGCGDATDRIPHGEQVTVacsEGDTGRIYKG 458
Cdd:COG3848 289 VGAEGATEILKDGQVVTV---DAERGVVYRG 316
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
1-468 |
1.15e-31 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 130.25 E-value: 1.15e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 1 MTDYILWLDELGMADLDKVGGKNSSLGEMignlSGLGVSVPGGFATTADAFREFLdqsglagriqdalehldAEDTRALA 80
Cdd:PRK05878 5 LENAVVLLDGGANQPRELLGGKGHGIDMM----RRLGLPVPPAFCITTEVCVRYL-----------------ADPGSTID 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 81 ATGRQIRDWImetplqpaleaaireAWAEMES--RYGQG---LAVAVRSSAT-----------------------AEDLP 132
Cdd:PRK05878 64 AIWDDVLDRM---------------RWLEAETgrTFGRGprpLLVSVRSGAAqsmpgmmdtilnlgindaveqalAAEGG 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 133 DASFAGQ-----QETFLNVRGL-----DEVLEKL----HAVFASLYNDRAIAYRVHHGFDHhDVALSAGIQLMV------ 192
Cdd:PRK05878 129 DPDFAADtrrrfTEMYRRIVGSgspppDDPYEQLraaiEAVFASWNSPRAVAYRRHHGLDD-DGGTAVVVQAMVfgnlda 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 193 RSGSGasgVMFTLDTESGYRNVVFVTSSYGLGESVVQGAVNPdefylfkpnleagkpavlrRSLGSKATRM--VYAEgsg 270
Cdd:PRK05878 208 NSGTG---VLFSRNPITGANEPFGEWLPGGQGEDVVSGLVDV-------------------APITALRDEQpaVYDE--- 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 271 vltedtpealrnrfsisdddatrLAEMALTIEKHYGRPMDIEWGKdgESGQLFILQARPetvKSRSGQAMERFKL----- 345
Cdd:PRK05878 263 -----------------------LMAAARTLERLGRDVQDIEFTV--ESGKLWLLQTRS---AKRSAQAAVRLALqlhde 314
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 346 -----EET------------------------GDVLAEGRAIGQRIGTGVA--RVIESLDeMHDVAPGDVLVTDMTDPDW 394
Cdd:PRK05878 315 gliddAEAlrrvtpthvetllrpslqpearlaAPLLAKGLPACPGVVSGTAytDVDEALD-AADRGEPVILVRDHTRPDD 393
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 906867083 395 EPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVacsEGDTGRIYKGKLAFS-VAEDT 468
Cdd:PRK05878 394 VHGMLAAQGIVTEVGGATSHAAVVSRELGRVAVVGCGAGVAAALAGKEITV---DGYEGEVRQGVLALSaWSESD 465
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
378-450 |
9.88e-31 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 115.20 E-value: 9.88e-31
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 906867083 378 DVAPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVTVACSEG 450
Cdd:pfam00391 1 KLPEGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
344-458 |
4.66e-25 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 110.40 E-value: 4.66e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 344 KLEETGDVLAEGRAIGQRIGTGVARVIESLDEMHDVAPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELG 423
Cdd:PRK06354 474 KVHVVGAVVAKGQGIGRKSVSGKARVAKTAAEVAKVNEGDILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLG 553
|
90 100 110
....*....|....*....|....*....|....*
gi 906867083 424 IPAVVGCGDATDRIPHGEQVTVACSEGDtgrIYKG 458
Cdd:PRK06354 554 IPVIVGVKNATSLIKDGQIITVDAARGV---VYSG 585
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
337-746 |
4.01e-24 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 107.41 E-value: 4.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 337 GQAMErfkLEETGDVLAEGRAIGQR-IGTgvaRVIESLDEMHDVAPGD-----VLV-TDMTDPDWEPI-MKRAAAIVTNR 408
Cdd:PRK11177 110 GQAKA---LEELDDEYLKERAADVRdIGK---RLLKNILGLKIIDLSAiqeevILVaADLTPSETAQLnLKKVLGFITDI 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 409 GGRTCHAAIIARELGIPAVVGCGDATDRIPHGE---------QVTVACSEGDTGRI--YKGKLAFSVAEDT-LDEMPPAP 476
Cdd:PRK11177 184 GGRTSHTSIMARSLELPAIVGTGNITKQVKNGDylildavnnQIYVNPTNEVIEELkaVQEQYASEKAELAkLKDLPAIT 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 477 L-----KIMMN------VANADRafdfaqipN--HGIGLARLEFI-INRmigihpRALleySKQNEEVRAeidrriagya 542
Cdd:PRK11177 264 LdghqvEVCANigtvrdVEGAER--------NgaEGVGLYRTEFLfMDR------DAL---PTEEEQFQA---------- 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 543 dpvsfYvdklaegiATIAAPFAPNPVIVRLSDF---KSNEYANLiggeqyePEEENPMIGWRGASRYVD--ESFKPAFE- 616
Cdd:PRK11177 317 -----Y--------KAVAEAMGSQAVIVRTMDIggdKELPYMNL-------PKEENPFLGWRAIRIAMDrkEILHDQLRa 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 617 -LECRALKKVRetmglshvwAMIPFVRTVDEARDVVEVLEgfGLK---RGE-----QGLKLIMMCELPSNALLADQFLEH 687
Cdd:PRK11177 377 iLRASAFGKLR---------IMFPMIISVEEVRELKAEIE--ILKqelRDEgkafdESIEIGVMVETPAAAVIARHLAKE 445
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 906867083 688 FDGFSIGSNDMTQLTLGLDRDSALVAHRFDERNDAVKALLSMAIKACRDRGKYIGICGQ 746
Cdd:PRK11177 446 VDFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVLNLIKQVIDASHAEGKWTGMCGE 504
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
365-455 |
2.02e-23 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 105.51 E-value: 2.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 365 GVARVIESLDEMHDVAPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVT 444
Cdd:PRK08296 512 GPARVIRSADELSEVQEGEILVCPVTSPSWAPIFAKIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLR 591
|
90
....*....|.
gi 906867083 445 VacsEGDTGRI 455
Cdd:PRK08296 592 V---DGTKGVV 599
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
346-773 |
8.84e-22 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 100.84 E-value: 8.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 346 EETGDVlaegRAIGQRIgtgvarviesLDEMHDVAPGD-------VLVTDMTDPDW--EPIMKRAAAIVTNRGGRTCHAA 416
Cdd:PRK11061 293 ERAGDL----RALGQRL----------LFHLDDSEQGPnawperfILVADELTATLlaELPQDRLAGVVVRDGAANSHAA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 417 IIARELGIPAVVGcGDATDRIPHGEQVTVacsEGDTGRI-----------YKGKLA-----FSVAEDTLDEmpPAPLK-- 478
Cdd:PRK11061 359 ILVRALGIPTVMG-ADIQPSLLHQRLLIV---DGYRGELlvdpepvllqeYQRLISeeielSRLAEDDVNL--PAQLKsg 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 479 ----IMMNvanADRAFDFAQIPNH---GIGLARLE--FiinrmigihpraLLEYSKQNEEvraeidRRIAGYADPVSFYV 549
Cdd:PRK11061 433 erikVMLN---AGLSAEHEEKLGSrvdGVGLYRTEipF------------MLQSGFPSEE------EQVAQYQGMLQMFP 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 550 DKlaegiatiaapfapnPVIVRLSDfksneyanlIGGEQ---YEP-EEENPMIGWRGASRYVDEsfkPA-FELECRA-LK 623
Cdd:PRK11061 492 DK---------------PVTLRTLD---------IGADKqlpYMPiSEENPCLGWRGIRITLDQ---PEiFLIQVRAmLR 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 624 KVRETMGLSHVWAMIPFVRTVDEARDVV-----EVLE--GFGLKRGEQGlkliMMCELPSNALLADQFLEHFDGFSIGSN 696
Cdd:PRK11061 545 ANAATGNLSILLPMVTSIDEVDEARRLIdragrEVEEmlGYEIPKPRIG----IMIEVPSMVFMLPHLASRVDFISVGTN 620
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 906867083 697 DMTQLTLGLDRDSALVAHRFDERNDAVKALLSMAIKACRDRGKYIGICGQGPSDyPDLAQWLLDQGIESMSLNPDTV 773
Cdd:PRK11061 621 DLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGD-PMGALLLIGLGYRHLSMNGRSV 696
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
365-455 |
2.06e-20 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 96.88 E-value: 2.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 365 GVARVIESLdEMHDVAPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQVT 444
Cdd:PRK06241 780 GRARVILNP-EDADLEKGDILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVGVENATKLIKDGQRIR 858
|
90
....*....|.
gi 906867083 445 VacsEGDTGRI 455
Cdd:PRK06241 859 V---DGTEGYV 866
|
|
| PRK05865 |
PRK05865 |
sugar epimerase family protein; |
365-461 |
1.10e-10 |
|
sugar epimerase family protein;
Pssm-ID: 235630 [Multi-domain] Cd Length: 854 Bit Score: 65.45 E-value: 1.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 365 GVARVI--ESLDEMHdvaPGDVLVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATDRIPHGEQ 442
Cdd:PRK05865 748 GRVRIVrpETIDDLQ---PGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGAL 824
|
90
....*....|....*....
gi 906867083 443 VTVacsEGDTGRIYKGKLA 461
Cdd:PRK05865 825 VEV---DGATGEIHVVELA 840
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
120-336 |
6.31e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 56.15 E-value: 6.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 120 VAVRSSATAEDLPDASFAGQQETFLNVRG--LDEVLEKLHAVFASLyndraiayrvhhGFDHHDVALsagIQLMVRsGSG 197
Cdd:PRK05849 58 LIVRSSSRSEDSSSSSNAGAFLSILNVNAdsKDQLLKAIEKVIASY------------GTSKDDEIL---VQPMLE-DIV 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 906867083 198 ASGVMFTLDTESG--YRNVVFVTSsyGLGESVVQGavnpdefylfkpnleagkpavlrrslGSKATRMVYAEGSGVLTEd 275
Cdd:PRK05849 122 LSGVAMSRDPESGapYYVINYDES--GSTDSVTSG--------------------------SGGSATTVYHYRDALVFK- 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 906867083 276 tPEALRnrfsisdddatRLAEMALTIEKHYGR-PMDIEWGKDgESGQLFILQARPETVKSRS 336
Cdd:PRK05849 173 -PPRLK-----------KLIELIRELEALFGCdFLDIEFAID-EKEELYILQVRPITVPEKW 221
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
391-432 |
2.13e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 44.97 E-value: 2.13e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 906867083 391 DP--DWePIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGD 432
Cdd:PRK05849 717 DPgyDW-LFTKGIAGLITCYGGANSHMAIRAAELGLPAVIGVGE 759
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
408-445 |
4.73e-04 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 43.58 E-value: 4.73e-04
10 20 30
....*....|....*....|....*....|....*....
gi 906867083 408 RGGRTC-HAAIIARELGIPAVVGCGDATDRIPHGEQVTV 445
Cdd:PRK11377 424 SAGSPLsHSAIIARELGIGWICQQGEKLYAIQPEETLTL 462
|
|
| |
