|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
29-363 |
2.26e-142 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 407.30 E-value: 2.26e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDqDKVNAVVGHFCSSST 108
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVA-DGVVAVIGHYNSGAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd06342 80 IAAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGpqY 268
Cdd:cd06342 160 KALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGD--A 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 269 TNGIYMTFGKDP-RLIPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSVDTVMGKK 345
Cdd:cd06342 238 AEGVYATTPGAPpEKLPAAKAFLKAYKA-KFgePPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALRATDFDGVTGTI 316
|
330
....*....|....*...
gi 895889000 346 AWDSKGDLKVSDYVVYQW 363
Cdd:cd06342 317 SFDAKGDLTGPAFTVYQV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
10-373 |
1.24e-136 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 394.00 E-value: 1.24e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 10 LSLVLAGCLVTAFSARA---DIVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAV 86
Cdd:PRK15404 5 GKTLLAGCIALALSHAAladDIKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQAVAV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 87 ANRLVDqDKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKR 166
Cdd:PRK15404 85 ANKVVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILEKVKPKR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 167 VVIIHDKDTYGQGLADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQA 246
Cdd:PRK15404 164 IAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAGLKT 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 247 KFFSGDCIVNEEMVTAAGGPqyTNGIYMTFGKDPRLIPDGKAVIEKFRAGKFEPEG-YTLYSYASVQAIAAAFKATGGKD 325
Cdd:PRK15404 244 QFMGPEGVGNKSLSNIAGPA--SEGMLVTLPKRYDQDPANKAIVDAFKAKKQDPSGpFVWTTYAAVQSLAAGINRAGSDD 321
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 895889000 326 SAKASEWLKANSVDTVMGKKAWDSKGDLKVSDYVVYQWDDKGKYKEVQ 373
Cdd:PRK15404 322 PAKVAKYLKANTFDTVIGPLSWDEKGDLKGFEFGVFEWHADGTKTAAK 369
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
26-373 |
9.85e-96 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 287.98 E-value: 9.85e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 26 ADIVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCS 105
Cdd:COG0683 2 DPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDQDKVDAIVGPLSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 106 SSTMPASEVYSDAGIITITPGSTNPLITERGMSD-MFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADAT 184
Cdd:COG0683 82 GVALAVAPVAEEAGVPLISPSATAPALTGPECSPyVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAAF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 185 KAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFfsgdcivneemvtaag 264
Cdd:COG0683 162 KAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL---------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 265 gpqytngiymtfgkdprlipdGKAVIEKFRA-GKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSVDTVMG 343
Cdd:COG0683 226 ---------------------NKAFVKAYKAkYGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALEGLKFDGVTG 284
|
330 340 350
....*....|....*....|....*....|
gi 895889000 344 KKAWDSKGDLkVSDYVVYQWDDKGKYKEVQ 373
Cdd:COG0683 285 PITFDPDGQG-VQPVYIVQVKADGKFVVVE 313
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-352 |
4.93e-84 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 258.63 E-value: 4.93e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIDEDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITErGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDK-DTYGQGLADATKAA 187
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTK-GGDYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYDVsSDYSKGLAKAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDcIVNEEMVTAAGGPQ 267
Cdd:cd06347 160 FEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGD-GWDSPELLELGGDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 268 YTNGIYMTFG--KDPRliPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKAN-SVDTVM 342
Cdd:cd06347 239 VEGVYFTTHFspDDPS--PEVQEFVKAYKA-KYgePPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTkDFEGVT 315
|
330
....*....|
gi 895889000 343 GKKAWDSKGD 352
Cdd:cd06347 316 GTITFDPNGN 325
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-352 |
3.64e-81 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 251.33 E-value: 3.64e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDDKVVAVIGDFSSSCS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITerGMSD-MFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06349 81 MAAAPIYEEAGLVQISPTASHPDFT--KGGDyVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGP- 266
Cdd:cd06349 159 AKALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDAa 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 267 --QYTNGIYMTFGKDPRLipdgKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGkDSAKASEWLKANSVDTVM 342
Cdd:cd06349 239 egVYLSSPFFPESPDPEV----KEFVKAYKA-KYgeDPDDFAARAYDAVNILAEAIEKAGT-DREAIRDALANIKDFSGL 312
|
330
....*....|.
gi 895889000 343 -GKKAWDSKGD 352
Cdd:cd06349 313 tGTITFDENGD 323
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
30-315 |
4.85e-78 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 242.23 E-value: 4.85e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06268 2 IGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVDDDKVLAVVGHYSSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd06268 82 AAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGgpQYT 269
Cdd:cd06268 162 ALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLGG--EAA 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 895889000 270 NGIYMTFGKDPRL-IPDGKAVIEKFRA-GKFEPEGYTLYSYASVQAIA 315
Cdd:cd06268 240 EGVVVAVPWHPDSpDPPKQAFVKAYKKkYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-360 |
5.51e-77 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 240.59 E-value: 5.51e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19980 2 IGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLITDDKVPAIIGAWCSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd19980 82 AVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGPqyT 269
Cdd:cd19980 162 AKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDA--A 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 270 NGIYMTFGKDPRLIPDG-KAVIEKFRAG-KFEPEGYTLYSYASVQAIAAAFKATGGKD-SAKASEWLKANSVDTVMGKKA 346
Cdd:cd19980 240 EGVYGASIYAPTADNPAnKAFVAAYKKKyGEPPDKFAALGYDAVMVIAEAIKKAGSTDpEKIRAAALKKVDYKGPGGTIK 319
|
330
....*....|....
gi 895889000 347 WDSKGDLKVSDYVV 360
Cdd:cd19980 320 FDEKGQAHKNVVLV 333
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-315 |
7.90e-72 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 225.95 E-value: 7.90e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19984 2 IGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKLINVDKVKAIIGGVCSSETL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITErgMSD-MFRMCGRDDQQGQVASDFIIDKLKaKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd19984 82 AIAPIAEQNKVVLISPGASSPEITK--AGDyIFRNYPSDAYQGKVLAEFAYNKLY-KKVAILYENNDYGVGLKDVFKKEF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGgpQY 268
Cdd:cd19984 159 EELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAG--EA 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 895889000 269 TNGIYMTFGKDPrlIPDGKAVIEKFRAGKF----EPEGYTLYSYASVQAIA 315
Cdd:cd19984 237 AEGVIFTYPAFD--DSSEKKQKFFFYRYKEkygkEPDIYAALAYDAVMILA 285
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-315 |
1.96e-69 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 220.23 E-value: 1.96e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIYQDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGpqY 268
Cdd:cd19988 161 KKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGD--A 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 895889000 269 TNGIYMTFGKDPRLIPDG-KAVIEKFRAgKF--EPEGYTLYSYASVQAIA 315
Cdd:cd19988 239 AEGAIATTPFLPDSDDPKvSAFVEKYKK-RYgeEPDVFAAQAYDAMNILA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-363 |
1.16e-67 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 217.04 E-value: 1.16e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGI---NGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCS 105
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGIkslGGAKIELVVADTQSDPEVAASEAERLITQEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 106 SSTMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIID-----KLKAKRVVIIHDKDTYGQGL 180
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLKElakkkGKKIKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 181 ADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFF--SGDCIVNEE 258
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKAIigVGGGYSDPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 259 MVTAAGGpqYTNGIYMT--FGKD-PRLIPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGKDsAKASEWL 333
Cdd:cd06340 241 FLKALGK--DAEGVFSVvpWSPDlAKKKPGAKEVNERYKK-KYgeDMTGHAARAYTAAWVLADALERAGSTD-PEAIRAA 316
|
330 340 350
....*....|....*....|....*....|....*.
gi 895889000 334 KANSVDT------VMGKKAWDSKGDLKVSDYVVYQW 363
Cdd:cd06340 317 AALTLDIpeglimPGGGVKFDEKGQNVLARPVVVQW 352
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-322 |
4.21e-65 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 209.34 E-value: 4.21e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06346 2 IGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDVEGVPAIVGAASSGVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSDM-FRMCGRDDQQGQVASDFIIDKLkAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd06346 82 AVASVAVPNGVVQISPSSTSPALTTLEDKGYvFRTAPSDALQGVVLAQLAAERG-FKKVAVIYVNNDYGQGLADAFKKAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRG---VQDVMYEglsRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQA-KFFSGDCIVNEEMVTAAg 264
Cdd:cd06346 161 EALGgtvTASVPYE---PGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDFtPWIGTDGLKSDDLVEAA- 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 265 GPQYTNGIYMTfGKDPRLIPDGKAVIEKFRA-GKFEPEGYTLYSYASVQAIAAAFK-ATG 322
Cdd:cd06346 237 GAEALEGMLGT-APGSPGSPAYEAFAAAYKAeYGDDPGPFAANAYDAVMLLALAYEgASG 295
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-354 |
9.67e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 206.31 E-value: 9.67e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 27 DIVIGVAGPFTGPNatygDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSS 106
Cdd:cd06344 1 DIVIGVAWPFAPDG----DLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADNPDVVAVIGHRSSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 107 STMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDkLKAKRVVIIHDKDTYGQGLADATKA 186
Cdd:cd06344 77 VAIPASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAAR-QGYKRIVIYYDDDSYGKGLANAFEE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 187 ALAKRGVQDVMYEGLSRGEKDFNALVTKIGA-QKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGg 265
Cdd:cd06344 156 EARELGITIVDRRSYSSDEEDFRRLLSKWKAlDFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAG- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 266 pQYTNGIYMTFG---KDPRliPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKA-NSVDT 340
Cdd:cd06344 235 -KAAEGVVVATVfdpDDPR--PEVRAFVEAFRKKyGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKIASALRFlENWEG 311
|
330
....*....|....
gi 895889000 341 VMGKKAWDSKGDLK 354
Cdd:cd06344 312 VTGTYSFDANGDVV 325
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-363 |
5.14e-63 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 205.12 E-value: 5.14e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGE----KIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFC 104
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGGgkkrPVELVYYDDQSDPATAVRLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 105 SSSTMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDK-LKAKRVVIIHDKDTYGQGLADA 183
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAELgPKPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 184 TKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAA 263
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTVGPAFPAFREA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 264 GGPQyTNGIYMTFGKDPRL----IPDGKAVIEKFRA-GKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSV 338
Cdd:cd06338 241 LGKD-AEGVLGPSQWEPSLpykvFPGAKEFVKAYKEkFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDALASLDF 319
|
330 340
....*....|....*....|....*
gi 895889000 339 DTVMGKKAWDSKGDLKVSDYVVYQW 363
Cdd:cd06338 320 DTVYGPIKFDETGLQIGKPMVVVQW 344
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
28-368 |
8.41e-62 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 201.73 E-value: 8.41e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 28 IVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSS 107
Cdd:pfam13458 2 IKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVDQDGVDAIVGGVSSAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 108 TMPASEVYSDAGIITITPGSTNPlitERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:pfam13458 82 ALAVAEVLAKKGVPVIGPAALTG---EKCSPYVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGPQ 267
Cdd:pfam13458 159 AKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKLVGLGGDEPDLKALGGD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 268 YTNGIYMT--FGKDPRLiPDGKAVIEKF--RAGKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSVDTVMG 343
Cdd:pfam13458 239 AAEGVYATvpFFPDLDN-PATRAFVAAFaaKYGEAPPTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRALPYDGPFG 317
|
330 340
....*....|....*....|....*
gi 895889000 344 KKAWDSKGDLKVSDYVVYQWDDKGK 368
Cdd:pfam13458 318 PVGFRAEDHQAVHCMYLVQVKADGK 342
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
29-367 |
4.29e-61 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 200.18 E-value: 4.29e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTgpnATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLITEDKVDAIVGGFRSEVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSD------MFRMCGRDDQQGQVASDFIID----KLKAKRVVIIHDKDTYGQ 178
Cdd:cd06345 78 LAAMEVAAEYKVPFIVTGAASPAITKKVKKDyekykyVFRVGPNNSYLGATVAEFLKDllveKLGFKKVAILAEDAAWGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 179 GLADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGD-CIVNE 257
Cdd:cd06345 158 GIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGINvPAQDP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 258 EMVTAAGGpqytNGIYMTF----GKDPRLIPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGKDSAKASE 331
Cdd:cd06345 238 EFWENTGG----AGEYEITlafaAPKAKVTPKTKPFVDAYKK-KYgeAPNYTAYTAYDAIYILAEAIERAGSTDPDALVK 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 895889000 332 WLKANSVDTVMGKKAWDSKGD-----LKVSDYVVY---QWDDKG 367
Cdd:cd06345 313 ALEKTDYEGVRGRIKFDKKDEyphdvKYGPGYVTGlifQWQDGG 356
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-315 |
7.17e-61 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 197.90 E-value: 7.17e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19981 2 IGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEQDKVVAVVSGSYSGPTR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGmSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd19981 82 AAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGgpQYT 269
Cdd:cd19981 161 KLGAEIVSEYAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAG--SAA 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 895889000 270 NGIYMT--FGKDPRLiPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIA 315
Cdd:cd19981 239 EGVIITtsLNRDSDR-PITQKFIKEYRKRyGIDPDMVAASTYDAVMVLA 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-348 |
1.15e-57 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 190.91 E-value: 1.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYG-DQYWhGATQAAEDINAAGGI--NGE--KIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHF 103
Cdd:cd06336 1 KIGFLGPLSGPAAAWGlPMLR-GLELAADEINAAGGIkvGGKkyKVEVVSYDDKYTPAEAVAAARRLVSQDGVKFIFGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 104 CSSSTMPASEVYSDAGIITITPGSTNPlITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADA 183
Cdd:cd06336 80 GSAIAAAVQPVTERNKVLLLTAAFSDP-ILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 184 TKAALAKRG---VQDVMYEglsRGEKDFNALVTKIGAQKPDVVFFGGCHP-EAGPLVRQMREQGVQAKFFSGDCIVNEEM 259
Cdd:cd06336 159 FVAAWKAAGgevVAEEFYD---RGTTDFYPVLTKILALKPDALDLGGSSPgPAGLIIKQARELGFKGPFVSEGGAKADEI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 260 VtAAGGPQYTNGIYMTFGKDPRLI--PDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKA 335
Cdd:cd06336 236 L-KEVGGEAAEGFIGVLPADDDPIasPGAKAFVERYKK-KYgePPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAALA 313
|
330
....*....|....*
gi 895889000 336 NS--VDTVMGKKAWD 348
Cdd:cd06336 314 MLspDETLFGKLKWG 328
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
29-328 |
1.87e-56 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 187.76 E-value: 1.87e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEEDKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPlITERGMSDMFRMCGRDDQQGQVASDFIIDKlKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAA-IVEPVRKWVFKTPQSDSLVAEAILDYMKKK-GIKKVALLGDSDAYGQSGRAALKKLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGPqy 268
Cdd:cd06333 159 PEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGKA-- 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 269 TNGIYMTFGK--DPRLIPDG---KAVIEKFRA---GKF--EPEGYTLYSYASVQAIAAAFKATGGKDSAK 328
Cdd:cd06333 237 AEGVILPAGKllVADQLPDSdpqKKVLLEFVKayeAKYgeGPSTFAGHAYDALLLLVEAIEPAGGTDRAA 306
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
28-323 |
4.11e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 187.39 E-value: 4.11e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 28 IVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSS 107
Cdd:cd06343 7 IKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVEQDKVFAIVGGLGTPT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 108 TMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06343 87 NLAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGLKEA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDcIVNEEMVTAAGGPQ 267
Cdd:cd06343 167 LKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSS-VSADPTTLAKAGGD 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 895889000 268 YTNGIYMT-FGKDPRLI--PDGKAVIEKFRA--GKFEPEGYTLYSYASVQAIAAAFKATGG 323
Cdd:cd06343 246 AAEGVYSAsYLKDPTDAddPAVKEFREAYKKyfPDDPPNAYALYGYAAAQVFVEALKRAGK 306
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-315 |
2.35e-55 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 183.60 E-value: 2.35e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19986 2 IGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDKVVAVIGPHYSTQVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITpGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd19986 82 AVSPLVKEAKIPVIT-GGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAALK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFF-SGDCIVNEEMVTAaggPQY 268
Cdd:cd19986 161 ALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIgSSSFATPTVLLLA---GEA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 895889000 269 TNGIY-MTFGKDPRLIPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIA 315
Cdd:cd19986 238 LEGIYsVTDFVPSDPDPKVQAFVKKYKAKyGEDPDLYSAWYYDAMYLLA 286
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-328 |
3.81e-55 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 184.73 E-value: 3.81e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIDKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSD---MFRMCGRDDQQGQVASDFIIDKlKAKRVVIIHDKDTYGQGLADATK 185
Cdd:cd06335 81 LATIPILQEAKIPLIIPVATGTAITKPPAKPrnyIFRVAASDTLQADFLVDYAVKK-GFKKIAILHDTTGYGQGGLKDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 186 AALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGG 265
Cdd:cd06335 160 AALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELAGP 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 895889000 266 pqYTNGIYM--TFGKDPRLiPDGKAVIEKFRAGKFEPEGYTLYS----YASVQAIAAAFKATGGKDSAK 328
Cdd:cd06335 240 --LAEGTIMtqTFIEDYLT-PRAKKFIDAYKKKYGTDRIPSPVSaaqgYDAVYLLAAAIKQAGSTDGKK 305
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-360 |
1.41e-53 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 180.12 E-value: 1.41e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06348 2 IGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLINQDKVLAILGPTLSSEAF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGmSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHD-KDTYGQGLADATKAAL 188
Cdd:cd06348 82 AADPIAQQAKVPVVGISNTAPGITDIG-PYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLYDqDDAFTVSGTKVFPAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGgpQY 268
Cdd:cd06348 161 KKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKLAG--KA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 269 TNGIYMTFGKDP-RLIPDGKAVIEKFRA--GKfEPEGYTLYSYASVQAIAAAFKATGGK------DSAKASEWLKANsVD 339
Cdd:cd06348 239 AEGVIVGSAWSPdNPDPKNQAFVAAYKEkyGK-EPDQFAAQAYDAAYILAEAIKKAGSTtdradlRDALARILIAKD-FE 316
|
330 340
....*....|....*....|.
gi 895889000 340 TVMGKKAWDSKGDLKVSDYVV 360
Cdd:cd06348 317 GPLGPFSFDADRDGIQPPVVL 337
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
30-344 |
8.68e-50 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 170.43 E-value: 8.68e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06330 2 IGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVLQEGVDFLIGTISSGVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSD-MFRMCGRDDQQGQVASDFIIDKLK-AKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06330 82 AVAPVAEELKVLFIATDAATDRLTEENFNPyVFRTSPNTYMDAVAAALYAAKKPPdVKRWAGIGPDYEYGRDSWAAFKAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQ-DVMYEGLSR-GEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGV--QAKFFSGDciVNEEMVTAA 263
Cdd:cd06330 162 LKKLKPDvEVVGELWPKlGATDYTAYITALLAAKPDGVFSSLWGGDLVTFVKQAKPYGLfdKTKVVSGL--GGGSEVLQA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 264 GGPQYTNGIYMTfGKDPRLIPD---GKAVIEKFRA-GKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSVD 339
Cdd:cd06330 240 LGKEMPEGLIGG-GRYPFGWPDtplNKAFVEAYRAkYGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKVIAALEGLTFD 318
|
....*
gi 895889000 340 TVMGK 344
Cdd:cd06330 319 TPGGK 323
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-252 |
1.64e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 160.52 E-value: 1.64e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19982 2 IGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSQDKVPLIVGGYSSGITL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd19982 82 PVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAARRFAK 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGD 252
Cdd:cd19982 162 KRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAGG 224
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-275 |
1.24e-43 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 153.59 E-value: 1.24e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVAnRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19985 2 IAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAA-QIIVSDKALAVIGHYYSSASI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERgmSD-MFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd19985 81 AAGKIYKKAGIPAITPSATADAVTRD--NPwYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFEATA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGA------QKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTA 262
Cdd:cd19985 159 RALGLKVLKKWSFDTDSSQLDQNLDQIVDelkkapDEPGVIFLATHADEGAKLIKKLRDAGLKAPIIGPDSLASESFAQG 238
|
250 260
....*....|....*....|.
gi 895889000 263 -AGGPQ-------YTNGIYMT 275
Cdd:cd19985 239 fAEYPEekeepgyYTDGIYAT 259
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
35-248 |
1.86e-39 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 142.44 E-value: 1.86e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 35 PFTGPNATYGDQYWHGATQAAEDINAAG-GINGEKIKLVQGDDACEPKQAVAVANRLVD--------------------- 92
Cdd:cd04509 17 PCGDIVAQYGIQRFEAMEQALDDINADPnLLPNNTLGIVIYDDCCDPKQALEQSNKFVNdliqkdtsdvrctngeppvfv 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 93 -QDKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTNPLITERGMSDMF-RMCGRDDQQGQVASDfIIDKLKAKRVVII 170
Cdd:cd04509 97 kPEGIKGVIGHLCSSVTIPVSNILELFGIPQITYAATAPELSDDRGYQLFlRVVPLDSDQAPAMAD-IVKEKVWQYVSIV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 171 HDKDTYGQGLADATKAALAKRGVQDVMYEGL--SRGEKDFNALVTKIGAQKP-DVVFFGGCHPEAGPLVRQMREQGVQAK 247
Cdd:cd04509 176 HDEGQYGEGGARAFQDGLKKGGLCIAFSDGItaGEKTKDFDRLVARLKKENNiRFVVYFGYHPEMGQILRAARRAGLVGK 255
|
.
gi 895889000 248 F 248
Cdd:cd04509 256 F 256
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
30-344 |
2.31e-39 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 142.74 E-value: 2.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06331 2 IGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQQDKVDAIVGPITSATRN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITItpgstNPLITERGMSD--MFRMCGRDDQQGQVASDFIIDKlKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06331 82 AVAPVAERAKVPLL-----YPTFYEGGECSpyLFCFGEVPNQQLDPLIPWLMEE-YGKKFYLIGSDYVWPRTMNDAARRV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAAGGPQ 267
Cdd:cd06331 156 IEAHGGEVVGEEYLPLGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLRRKVRIAALLFDENTLAGLGAEA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 268 ----YTNGIYMTFGKDprliPDGKAVIEKFRAgKFEPEGYTLYS-----YASVQAIAAAFKATGGKDSAKASEWLKANSV 338
Cdd:cd06331 236 aegiYSVLSYFQSLDT----PENKAFVAAYRK-KFGEDAPPITSlseaaYEAVHLYAAAVEKAGSTDPEAVIAALPGVSF 310
|
....*.
gi 895889000 339 DTVMGK 344
Cdd:cd06331 311 DGPQGP 316
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-315 |
1.01e-35 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 132.32 E-value: 1.01e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQdKVNAVVGHFCSSSTM 109
Cdd:cd19983 2 IGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAG-GVVAIIGHMTSAMTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITerGMSDMF-RMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKD--TYGQGLADATKA 186
Cdd:cd19983 81 AVLPVINEAKVLMISPTVSTPELS--GKDDYFfRVTPTTRESAQALARYAYNRGGLRRVAVIYDLSnrAYSESWLDNFRS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 187 ALAKRG---VQDVMYEglSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTAA 263
Cdd:cd19983 159 EFEALGgriVAEIPFS--SGADVDFSDLARRLLASKPDGLLLVASAVDTAMLAQQIRKLGSKIPLFSSAWAATEELLELG 236
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 895889000 264 GgpQYTNGI-----YMTFGKDPRLIPDGKAVIEKFRAgkfEPEGYTLYSYASVQAIA 315
Cdd:cd19983 237 G--KAVEGMlfsqaYDRNSSNPRYLAFKEAYEERFGR---EPSFAAAYAYEAAMVLA 288
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
28-275 |
1.61e-35 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 132.70 E-value: 1.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 28 IVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSS 107
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIEEDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 108 TMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFYQNDAFGLAGLEGAKKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVM---YEglsRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDcIVNEEMVTAAG 264
Cdd:cd19978 161 LKKRGLTPVAegsYT---RNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVS-FVGSEALALEL 236
|
250
....*....|.
gi 895889000 265 GPqYTNGIYMT 275
Cdd:cd19978 237 GD-YGEGVIVS 246
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
28-267 |
5.94e-35 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 131.13 E-value: 5.94e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 28 IVIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSS 107
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIEQDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 108 TMPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDDQQGQVasdfIIDKLKA---KRVVIIHDKDTYGQGLADAT 184
Cdd:cd06326 81 VEAVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADEVEK----IVRHLATlglKRIAVVYQDDPFGKEGLAAA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 185 KAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDcIVNEEMVTAAG 264
Cdd:cd06326 157 EAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLS-VVGAAALAKAL 235
|
...
gi 895889000 265 GPQ 267
Cdd:cd06326 236 GDA 238
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
30-360 |
5.04e-32 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 123.09 E-value: 5.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINaaGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06332 2 IGLLAPLTGPFAALGEDMVRGFELALEEVG--GEVAGRKVELVVEDDAGDPDTAVTKARKLVEQDKVDVLIGPLSGDEGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMSD-MFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd06332 80 AVAPYAKEPGVPFINPVAGADDLTQRAKAPnFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRG---VQDVMYEGlsrGEKDFNALVTKIGAQKpDVVFFGGCHPEAGPLVRQMREQGVQAK-FFSGDCIVNEEMVTAAG 264
Cdd:cd06332 160 EAAGgevVQEIWVPL---GTTDFSPYIAQIPSAD-DAVFAFLGGADAVRFLKQYREFGLKDKiPLIGGGTTVDESVLPAM 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 265 GPQ----YTNGIYMtfgkDPRLIPDGKAVIEKFRA-GKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEW--LKANS 337
Cdd:cd06332 236 GDAalgiISASHYA----EGLDNPENKKFVAAYKKkFGKLPSLYAAGGYDGAQAILEALEAVGGDVSDKQALAaaLRKVK 311
|
330 340
....*....|....*....|...
gi 895889000 338 VDTVMGKKAWDSKGDLKVSDYVV 360
Cdd:cd06332 312 FDSPRGPFSFDENRNPVQNVYIR 334
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
30-315 |
2.02e-31 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 120.46 E-value: 2.02e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd19989 2 IGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVEQDGVDFLTGAVSSAVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGS-TNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLkAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd19989 82 AVAPKAAELKVPYLVTVAaDDELTGENCNRYTFRVNTSDRMIARALAPWLAENG-GKKWYIVYADYAWGQSSAEAFKEAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKF-FSGDCIVNEEMVTAAGGPQ 267
Cdd:cd19989 161 EELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLGKKYkIVGGILSIEPLALPALGDA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 895889000 268 yTNGIYMTFGKDPRL-IPDGKAVIEKFRAGKFEPEGYTLY-SYASVQAIA 315
Cdd:cd19989 241 -AEGVYGGVRYPPTLdTPANRAFVEAYEKEYGEAPDNFAGeAYEAMQALA 289
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
30-372 |
1.48e-26 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 108.54 E-value: 1.48e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDI-NAAGGingEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06360 2 IGVLLPLTGPLAVNGEDVRDGFELYFDEIgNQVAG---RKIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVSSAVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGST-NPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06360 79 YAVRDYVVEQKIPLVISNAGaAPLTQELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFART 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRG---VQDVmYEGLsrGEKDFNALVTKIGAQKPDVV--FFGGchPEAGPLVRQMREQGVQAKF--FSGDCIVNEEMV 260
Cdd:cd06360 159 FKQAGgkvVQEI-YPPL--GTADFAPYLARIQQDAADAVwaFFAG--ADAIRFVKQYDEYGLKGKLplVGIGGLVDDAIL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 261 TAAGgpQYTNGIYMTFGKDPRL-IPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGK--DSAKASEWLKA 335
Cdd:cd06360 234 PEQG--DAALGIVSYLHYSAALdTPENKAFVQAYRK-KYgrDPGLYAEGGYVAARAIAEALEAVKGNveDKEAFLEALRK 310
|
330 340 350
....*....|....*....|....*....|....*..
gi 895889000 336 NSVDTVMGKKAWDSKGDLKVSDYVVYQWDDKGKYKEV 372
Cdd:cd06360 311 VRFEAPRGPFRFDPYQQAVVTTYIRRVEKVDGKLVNV 347
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
51-365 |
3.75e-25 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 104.39 E-value: 3.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 51 ATQAAEDINAAGGIN-GEKIKLVQGDDACEPKQAVAVANRLVdQDKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTN 129
Cdd:pfam01094 6 VRLAVEDINADPGLLpGTKLEYIILDTCCDPSLALAAALDLL-KGEVVAIIGPSCSSVASAVASLANEWKVPLISYGSTS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 130 PLITERGMSDMF-RMCGRDDQQGQVASDfIIDKLKAKRVVIIHDKDTYGQGLADATKAALAKRGVQDVMYEGLSRG---E 205
Cdd:pfam01094 85 PALSDLNRYPTFlRTTPSDTSQADAIVD-ILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIRVAYKAVIPPAqddD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 206 KDFNALVTKIgAQKPDV-VFFggCHPEAG-PLVRQMREQGVQAKFF----SGDCIVNEEMVTAAGGPQYTNGIYMTFgkd 279
Cdd:pfam01094 164 EIARKLLKEV-KSRARViVVC--CSSETArRLLKAARELGMMGEGYvwiaTDGLTTSLVILNPSTLEAAGGVLGFRL--- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 280 prLIPDGKAViEKFRAGKF------------EPEGYTLYSYASVQAIAAAFKATGGKDSAKAS--------------EWL 333
Cdd:pfam01094 238 --HPPDSPEF-SEFFWEKLsdekelyenlggLPVSYGALAYDAVYLLAHALHNLLRDDKPGRAcgalgpwnggqkllRYL 314
|
330 340 350
....*....|....*....|....*....|..
gi 895889000 334 KANSVDTVMGKKAWDSKGDLKVSDYVVYQWDD 365
Cdd:pfam01094 315 KNVNFTGLTGNVQFDENGDRINPDYDILNLNG 346
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
30-346 |
4.84e-24 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 101.20 E-value: 4.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQdKVNAVVGhfCSSSTM 109
Cdd:cd06329 2 IAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQ-GIRFVLQ--GNSSAV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PAS---------EVYSDAGIITITPGSTNPLITERGMSD-MFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQG 179
Cdd:cd06329 79 AGAlidaiekhnQRNPDKRVLFLNYGAEAPELTGAKCSFwHFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGRD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 180 LADATKAALAKR--GVQDVmyeglsrGE--------KDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFF 249
Cdd:cd06329 159 VAAAAKKNLKKKrpDIEIV-------GEdlhplgkvKDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFY 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 250 SgdCIVNEEMVTAAGGPQYTNGIYM-TFGKDPRLIPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIAAAFKATGGKDSA 327
Cdd:cd06329 232 T--YYADGPGAPAAIGEAGVGRLVAvAYWHPNPKTPELEKFAEAFRAKyGRYPDFNIGRTYMGVEMLAAAIKKAGSTDPE 309
|
330
....*....|....*....
gi 895889000 328 KASEWLKANSVDTVMGKKA 346
Cdd:cd06329 310 KVAKALEGLSFDTPGGPVT 328
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
29-329 |
2.53e-23 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 99.30 E-value: 2.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHG-------ATQAAedinaaGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVG 101
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGfelgleyATDGT------MEVDGRKIEVIVKDDQGDPDTAKAAATELIGDDGVDILVG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 102 HFCSSSTMPASEVYSDAGIITITPGSTNPLITERGMSD-MFRMcGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGL 180
Cdd:cd06328 75 TVSSAVALALAPVAEQNKKILIVGPAAADSITGENWNKyTFRT-SRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 181 ADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMV 260
Cdd:cd06328 154 VAAFKKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLWQQLADQGVLDDIKVVTGGPDIATL 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 895889000 261 tAAGGPQYTNGIYMTFGKDPrlIPDGK---AVIEKFR-AGKFEPEGYTLYSYASVQAIAAAFKATGGKDSAKA 329
Cdd:cd06328 234 -AALGDALPGIEGLTYYYYG--LPKNPvndWLVKAHKeRYNAPPDLFTAGGFAAAQAVVRALEKAGGDTDVEK 303
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
30-349 |
2.75e-23 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 99.23 E-value: 2.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINaaGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd20014 2 IGLLLPYSGVYAALGEDIRNGFQLYLDEHG--GKLGGRPIELVKEDDEADPDVALQKARKLIEQDKVDVLVGPVSSGVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPG-STNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKLKaKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd20014 80 AIRDVVEQAKVPLIVANaGANALTRAACSPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAGFKEGF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 AKRGVQDVMYEGLSRGE-KDFNALVTKIGAQKPDVV--FFGGchPEAGPLVRQMREQGVQAKF-FSGDCIVNEEMVTAAG 264
Cdd:cd20014 159 EAAGGKVVGEIWTPLGTtTDFSPYLTQIAASGPDAVyaFFAG--ADAVRFVKQYAEFGLKGKIpLYGPGFLTDEDVLPAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 265 GPQYTNGIYMTFGKDPRLIPDGKAVIEKFRAgKF--EPEGYTLYSYASVQAIAAAFKATGGK--DSAKASEWLKANSVDT 340
Cdd:cd20014 237 GEAAEGIITVLHYAPTLDNPANRAFVAAYQA-KYgrLPDVYAVQGYDAAQVIDAALEAVGGDtsDKDILAAALELGSIDS 315
|
....*....
gi 895889000 341 VMGKKAWDS 349
Cdd:cd20014 316 PRGPFRFDP 324
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-326 |
3.27e-23 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 98.92 E-value: 3.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGP------NATYGDQYWHGAtqaaedINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGH 102
Cdd:cd06341 1 KIGLIYPDTGPgaasfsAARAGAEARFGL------ANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 103 FcSSSTMPASEVYSDAGIITITPGSTNPliTERGMSDMFRMCGRDDQQGQVASDFIIDKLKAKRVVIIHDKDTYGQGLAD 182
Cdd:cd06341 75 S-SAASGSANDYLAQAGIPVVGGAGVSV--WCFRNMFSNFFSLGGGGSTTTYGQYAAALGGTKAAVVVTDIPAASQQLAQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 183 ATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEMVTA 262
Cdd:cd06341 152 QLAASLRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAA 231
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 895889000 263 AGgpQYTNGIYMTFGKDPRL--IPDGKAviekFRA--GKFEPE------GYTLYSYASVQAIAAAFKATGGKDS 326
Cdd:cd06341 232 YG--AALAGVSVASTFLPFEadTPAVKA----YRAamAKYAPElqdplqQFALSGYIAADLFVRGLEAAGGCPT 299
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-367 |
9.36e-22 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 95.00 E-value: 9.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHfcssST 108
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYKRLKAQDGVVAILGW----GT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MP----ASEVYSDaGIITITPGSTNPLITERGMSD-MFRMCGRDDQQGQVASDFIID----KLKAKRVVIIHDKDTYGQG 179
Cdd:cd06334 77 GDtealAPRVAKD-KIPYISASYGRSLADDGKVFPyNFFVGATYSSQARALLKYIAQewggKLKGPKVAFVYHDSPFGRE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 180 LADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFSGDCIVNEEM 259
Cdd:cd06334 156 PIPALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFIGNIWGGDEDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 260 VTAAG----GPQYTNGIYmtFGKDPRLIPDgkavIEKFRAGKFEPEGYTLYS-----------YASVQAIAAAFKATGGK 324
Cdd:cd06334 236 IKLAGdaaeGYVGVSPFA--FGTDDPPGKE----IVEEVAKKGKGDGPEEVGtvyynrgwataMLAVEAIRRADKAGGGT 309
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 895889000 325 DS----AKASEWLKANSVDTVMGKKAWdSKGDLKVSDYV-VYQWDDKG 367
Cdd:cd06334 310 GLgnklKAGLERLKDFDLGGLAPPVTF-TPTDHRGGGVVrIYQWDGGK 356
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-350 |
1.96e-21 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 93.95 E-value: 1.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEdinAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVE---EYGGALGRPLKYITRDTEGKPGTGVRKVQEAIAQDGARFFIGGTLSSVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERgmsdmfrmCGRDDQQGQVAS--------DFIIDKL-KAKRVVIIHDKDTYGQG 179
Cdd:cd20378 78 LAVSEEAEKAGGVYITSGGADEITGSR--------CNRSTFRWSVPTygairqtvRPVIKAMpKAKRWYTITPQYVFGES 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 180 LADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFfsgdCIVneeM 259
Cdd:cd20378 150 LLKNAKEVLKEKGIEHVGNSYHSLGEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGLKRKM----KIL---V 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 260 VTAAG-------GPQYTNGIYMTFGKDPRL-IPDGKAVIEKFRAGKFEPEGYTL-YSYASVQAIAAAFKATGGKDSAKAS 330
Cdd:cd20378 223 AWSSGldqfqelGPDICEGVYFGAQYWHDVdTPANKALVKVYQAKFKETPSYALaAGYACTRMLLDAIDKAGSTDPAAVI 302
|
330 340
....*....|....*....|
gi 895889000 331 EWLKANSVDTVMGKKAWDSK 350
Cdd:cd20378 303 KALEGLKYDGITGDEEVRAA 322
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
29-250 |
1.92e-20 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 91.13 E-value: 1.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd19979 1 VIGLDADLSGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAADPDVLAVFGGLHSPVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSD--MFRMCGRDDQQGQVASDFIIDKlKAKRVVIIHDKDTYGQGLADATKA 186
Cdd:cd19979 81 LAELDFIHELKIPYLVPWAAATPITRNGYSPnyIFRLSVDDSLAGPFLVEYALKK-GCKRPALLLENTGWGRSNLKAMTK 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 895889000 187 ALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFS 250
Cdd:cd19979 160 ALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIIS 223
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
30-329 |
2.00e-20 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 90.78 E-value: 2.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINaaGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06359 2 IGFITTLSGPAAVLGQDMRDGFNLALEQLG--GKLGGLPVEVVVEDDQLKPDVAKQAAERLIERDKVDFVTGIIFSNVML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGST-NPLITERGMSDMFRMCGRDDQQGQVASDFIIDKlKAKRVVIIHDKDTYGQGLADATKAAL 188
Cdd:cd06359 80 AVVKPVVDSKVFYISANAGpSDLAGKGCNPNFFVTSWQNDQLHEAAGKYANDK-GYKRVYLLAPNYQAGKDALAGFKRTY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 189 aKRGVQDVMYEGLsrGEKDFNALVTKIGAQKPDVVFF---GGchpeAG-PLVRQMREQGVQAK--FFSGDCIVNEEMVTA 262
Cdd:cd06359 159 -KGEVVGEIYTPL--GQLDFSAELAQIRAAKPDAVFAfypGG----MGvNFVKQYAQAGLKKKipLYTVGTLDDEDLLPA 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 895889000 263 AGGPQYtnGIYMTFGKDPRL-IPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIAAAFKATGGKDSAKA 329
Cdd:cd06359 232 MGDAAL--GVLSVSQWSPDLdNPENKRFVAAFRKKyGRPPSNYAAQGYDAALLIDAAVKAVGGDLSDKD 298
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
30-224 |
8.88e-19 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 86.11 E-value: 8.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTM 109
Cdd:cd06358 2 IGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGAVDAIVGMHTSAVRQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASE--------VYS--------DAGIITItpGSTnplitergmsdmfrmcgrDDQQGQVASDFIIDKLKAKRVVIIHDK 173
Cdd:cd06358 82 ALANavggrvpyVYTplyeggerTPGVYAI--GET------------------PEEQLRPALRWLADERRVRRWFLVGND 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 895889000 174 DTYGQGLADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVF 224
Cdd:cd06358 142 YVWPRASHAAARRYIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAVL 192
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
37-328 |
1.50e-18 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 85.43 E-value: 1.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 37 TGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTMPASEVYS 116
Cdd:cd06356 9 SGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLILRDKVDVVFGGITSASREAIRPILR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 117 DAGIITITPGstnplITERGMSDMFRMC-GRD-DQQGQVASDFIIDKLkAKRVVIIHDKDTYGQGLADATKAALAKRGVQ 194
Cdd:cd06356 89 RNKILYFYNT-----QYEGGVCDKNTFCtGSTpEQQVSPLIEWAIKKY-GKKVYIIAADYNFGQISADWVKKYAKKNGGE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 195 DVMYEGLSRGEKDFNALVTKIGAQKPDVV---FFGGCHPEagpLVRQMREQGVQAK-------FFSGdcivNEEMVTAag 264
Cdd:cd06356 163 VVGEEFFPLDVTDFGPTIQKIQAAKPDFVvslLVGGNHIS---FYRQWAAAGLKKKipivstvFGAG----NEHKVLS-- 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 895889000 265 gPQYTNGIYMTFGKDPRL-IPDGKAVIEKFRAgKFEPEGY----TLYSYASVQAIAAAFKATGGKDSAK 328
Cdd:cd06356 234 -PPELEGMYVSYSYFEELdTPANKAFVAKWRA-KYGDEPYinqeAVGVYNAVYLWAEAVEKAGSTEREA 300
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
29-347 |
1.90e-17 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 82.38 E-value: 1.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 29 VIGVAGPFTGPNATYGDQYWHGATQAAEDINAAG------------GINGEKIKLVQGDDACEPKQAVAVANRLVDQDKV 96
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVDNAKRLIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 97 NAVVGHFCSSSTMPASEVYSDAGII---TITPgsTNPLITERGMSDMFRMCGRDDQQGQVASDFIIDKL-KAKRVVIIHD 172
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLyfaGLSH--SNDTTGKDCHRYGFRECFNAHMSAKALAPYLVEKFgKDRKYFYLTA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 173 KDTYGQGLADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVF---FGGchpEAGPLVRQMREQGVQAKFf 249
Cdd:cd19987 159 DYTWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVLVlvlFGR---DMVNALKQAKQFGLLKKM- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 250 sgDCIV--NEEMVTAAGGPQYTNGIYMTFGKDPRLipDGKAVIEKFRAGKFE------PEGYTLYSYASVQAIAAAFKAT 321
Cdd:cd19987 235 --DIVVplLTAFMAESVGPEIMEGVLGTVNWHWSL--PDDYSYAFGKAEAFEkeygayPSQAAASAYVQVLQYAAAVERA 310
|
330 340
....*....|....*....|....*.
gi 895889000 322 GGKDSAKASEWLKANSVDTVMGKKAW 347
Cdd:cd19987 311 GSFDPPAVIRALEGHEYTLLKGEQYW 336
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
30-245 |
7.47e-16 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 77.70 E-value: 7.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAAEDINaagginGEKIKLVQGDDAcEPKQAVAVANRLVdQDKVNAVVGHFCSSSTM 109
Cdd:cd06339 2 IALLLPLSGPYAAAGQAIRDGIELALFDAG------GSRPELRVYDTG-GPEGAAAAYQQAV-AEGADLIIGPLLKSSVA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 110 PASEVYSDAGIITITPGSTNPLITERGMsdmFRMCGRDDQQGQVASDFIIDKLKaKRVVIIHDKDTYGQGLADATKAALA 189
Cdd:cd06339 74 ALAAAAQALGVPVLALNNDESATAGPGL---FQFGLSPEDEARQAARYAVQQGL-RRFAVLAPDNAYGQRVANAFREAWQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 895889000 190 KRGVQDVMYEGLSRGEKDFNALVTKIGA----------------------QKPDVVFFGGCHPEAGPLVRQMREQGVQ 245
Cdd:cd06339 150 ALGGTVVAVESYDPDETDFSAAIRRLLGvdqsearirqlgellefeprrrQDFDAIFLPAGPEQARLIAPQLAFYGAG 227
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
30-350 |
1.14e-15 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 77.30 E-value: 1.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYwHGATQAAEDINAaGGINGEKIKLVQGDDA-CEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd20013 2 VGVIGPFSGPFADYGKQF-DRGIDLYLKLHG-DKVGGRKVEVIYRDDGgPNPAVAKRLAQELIVRDKVQILIGFGFTPNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITErgMSDMF-RMCGRDDQQGQVASDFIIDKLKAKRVVIIHDkdtYGQGL--ADATK 185
Cdd:cd20013 80 LAVAPVATEAKTPTVIMNAATSSITR--KSPYFvRTSFTMWQVAYPMGKWAAKNGIKKAYTAVAD---YAPGHdaETAFK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 186 AALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFF---GGchPEAGPLVRQMREQGVQA---KFFSGDCIVNEEM 259
Cdd:cd20013 155 KAFEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVfvpAG--APSIGFLKAYAERGLKEagiKLLGTGDATDDDD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 260 VTAAGGPQ---YTNGIYMTfgKDPRliPDGKAVIEKFRAgKFEPEGY----TLYSYASVQAIAAAFKATGGK-DSAKASE 331
Cdd:cd20013 233 LPAMGDAAlglITAGHYSA--ALDS--PENKAFVAAYQK-AYGPDARpdfmAVAAYDGMALIYKMIKATGGKfDGDKAMA 307
|
330
....*....|....*....
gi 895889000 332 WLKANSVDTVMGKKAWDSK 350
Cdd:cd20013 308 AVKGLKWESPRGPISIDPE 326
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
54-295 |
5.73e-15 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 75.30 E-value: 5.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 54 AAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSS---TMPASEVYsDAGIItitpgstNP 130
Cdd:cd06355 26 AIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKLITQDKVAVIFGCWTSASrkaVLPVIEKY-NGLLF-------YP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 131 LITErGM---SDMFRMCGRDDQQGQVASDFIIDKLkAKRVVIIHDKDTYGQGLADATKAALAKRGVQDVMYEGLSRGEKD 207
Cdd:cd06355 98 VQYE-GLeqsPNIVYTGATPNQQILPAIDWLLENL-GKRFFLVGSDYVFPRTANKIIRDQLKALGGEVVGEEYVPLGGTD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 208 FNALVTKIGAQKPDVVF--FGGCHPEAgpLVRQMREQGVQAKF-----FSgdcIVNEEMvtAAGGPQYTNGIYMTFGKDP 280
Cdd:cd06355 176 FDAIVAKIKAFKPDVIVntLNGDSNIA--FFKQLAAAGITASDlpvlsFS---VSEAEL--RAIGPEELAGHYAAWNYFQ 248
|
250
....*....|....*.
gi 895889000 281 RL-IPDGKAVIEKFRA 295
Cdd:cd06355 249 SLdTPENQAFVEAFKA 264
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
51-247 |
2.70e-13 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 70.31 E-value: 2.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 51 ATQAA-EDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTMPASEVYSDAGIITITP---- 125
Cdd:pfam13433 23 ATLMAiEEINAAGGVLGRKIEPVVVDPASDWPLFAEKARKLIDQDKVRVVFGCWTSASRKAVLPVFERHNGLLFYPvqye 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 126 ---GSTNPLITerGMSdmfrmcgrDDQQGQVASDFIIDKLKaKRVVIIHDKDTYGQGLADATKAALAKRGVQDVMYEGLS 202
Cdd:pfam13433 103 gfeSSRNIFYT--GAA--------PNQQAIPAVDYLLSELG-KRFFLVGSDYVYPRTTNRILRAYLKAKGGEVVGERYLP 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 895889000 203 RGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAK 247
Cdd:pfam13433 172 LGSSDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGITAE 216
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
30-347 |
9.50e-13 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 68.37 E-value: 9.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQY-WHGATQAAEDinAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSST 108
Cdd:cd06327 2 IGVLTDLSGVYADLSGPGsVEAAKMAVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREWYDRDGVDAIVDVPNSAVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 109 MPASEVYSDAGIITITPGSTNPLITERGMSDMFRMCGRDD-QQGQVASDFIIDKLKaKRVVIIHDKDTYGQGLADATKAA 187
Cdd:cd06327 80 LAVQKLAKEKKKIAIVTGAGSSDLTGKACSPYGVHWAYDTyALARGTVKALVKQGG-KSWFFITADYAFGHSLEADATAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 188 LAKRGVQDVmyeGLSR---GEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKffsGDCIVN---EEMVT 261
Cdd:cd06327 159 VKAAGGKVV---GSVRhplGTTDFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDG---GQKLAAlllFITDI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 262 AAGGPQYTNGIYMTFGKDPRLIPDGKAVIEKFRAG-KFEPEGYTLYSYASVQAIAAAFKATGGKDSAKASEWLKANSVDT 340
Cdd:cd06327 233 HALGLDAAQGLYLTTAFYWDRDDATRAWAKRFFARtGKMPTMLQAGVYSAVLHYLKAVKAAGTDDADAVVAKMREMPVND 312
|
....*..
gi 895889000 341 VMGKKAW 347
Cdd:cd06327 313 FFAKNGR 319
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
37-344 |
7.47e-12 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 65.68 E-value: 7.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 37 TGPNATYGDQYWHGATQAAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGhfCSSStmpAS--EV 114
Cdd:cd06357 9 TGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERLLLEDGVRHIFG--CYTS---ASrkAV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 115 YsdagiititpgstnPLITERGmSDMFRMC---GRD------------DQQGQVASDFIIDKLKaKRVVIIHDKDTYGQG 179
Cdd:cd06357 84 L--------------PVVERHN-ALLWYPTpyeGFEyspnviytgavpNQHLLPLARYLLAHFG-KRVFLVGSNYVYPWE 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 180 LADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVF---FGgchPEAGPLVRQMREQGVQAK---FFSgdC 253
Cdd:cd06357 148 SNRVARELIEASGGEVVGERYVPLGDTDFAEIIEEIKSLKPDVVFstlVG---DSIYAFYRAYAEAGLDPAdmpIAS--L 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 254 IVNEEMVTAAGGP----QYTNGIYmtFGKDPRliPDGKAVIEKFRAgKFEPEGYTLY----SYASVQAIAAAFKATGGKD 325
Cdd:cd06357 223 TTSEAEVAAIGAEaaagHYTSAPY--FQSIDT--PENRAFVEAYRA-RFGDDAVTSAvaeaAYFQVHLLARAIERAGSDD 297
|
330
....*....|....*....
gi 895889000 326 SAKASEWLKANSVDTVMGK 344
Cdd:cd06357 298 PEAIRAALYGQEFDAPQGP 316
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
91-249 |
7.74e-10 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 59.62 E-value: 7.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 91 VDQDKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTNPLITERGMSDMF-RMCGRDDQQGQVASDfIIDKLKAKRVVI 169
Cdd:cd06350 90 IGPPNIVAVIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIRYPYFlRTVPSDTLQAKAIAD-LLKHFNWNYVST 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 170 IHDKDTYGQGLADATKAALAKRGVQDVMYEGLSRG--EKDFNALVTKIGAQ-KPDVVFFGGCHPEAGPLVRQMREQGVQA 246
Cdd:cd06350 169 VYSDDDYGRSGIEAFEREAKERGICIAQTIVIPENstEDEIKRIIDKLKSSpNAKVVVLFLTESDARELLKEAKRRNLTG 248
|
...
gi 895889000 247 KFF 249
Cdd:cd06350 249 FTW 251
|
|
| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
45-223 |
6.60e-09 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 56.66 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 45 DQYWHGATQ-------AAEDINAAGGI-NGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTMPASEVYS 116
Cdd:cd06269 9 HDYLESGAKvlpafelALSDVNSRPDLlPKTTLGLAIRDSECNPTQALLSACDLLAAAKVVAILGPGCSASAAPVANLAR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 117 DAGIITITPGSTNPLITERGMSDMF-RMCGRDDQQGQVASDfIIDKLKAKRVVIIHDKDTYGQGLADATKAALAKRGVQD 195
Cdd:cd06269 89 HWDIPVLSYGATAPGLSDKSRYAYFlRTVPPDSKQADAMLA-LVRRLGWNKVVLIYSDDEYGEFGLEGLEELFQEKGGLI 167
|
170 180
....*....|....*....|....*....
gi 895889000 196 VMYEGLSRG-EKDFNALVTKIGAQKPDVV 223
Cdd:cd06269 168 TSRQSFDENkDDDLTKLLRNLRDTEARVI 196
|
|
| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
54-194 |
8.92e-08 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 53.39 E-value: 8.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 54 AAEDINAAGGINGEKIKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTNPLIT 133
Cdd:cd19990 23 AVSDFNSDSSSYGTKLVLHVRDSKGDPLQAASAALDLIKNKKVEAIIGPQTSEEASFVAELGNKAQVPIISFSATSPTLS 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 895889000 134 ERGMSDMFRMCGRDDQQGQ-VASdfIIDKLKAKRVVIIHDKDTYGQGLADATKAALAKRGVQ 194
Cdd:cd19990 103 SLRWPFFIRMTHNDSSQMKaIAA--IVQSYGWRRVVLIYEDDDYGSGIIPYLSDALQEVGSR 162
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-363 |
9.51e-08 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 53.46 E-value: 9.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYG--DQYWHGatQAAEDINAAGGINGEK---IKLVQGDDACEPKQAVAVANRLVDQDKVNAVVGHFC 104
Cdd:cd06337 2 IGRVSPLTGPLAAFGeaDPWVLE--QIREAFADGGIKVGGKkypVEIVVRDSQSDPNRAGEAARDLILRDKVDLMLASGT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 105 SSSTMPASEVYSDAG---IITITPgsTNPLITERG--MSDMFRMC-----GRDDqqgqVASDFI--IDKLKAKRVV-IIH 171
Cdd:cd06337 80 PDTVNPVADQCEANGvpcISTDAP--WQAWFFGRGgdPAKGFKWTfhffwGLED----IAANFLgmWDQVPTNKVVgLLW 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 172 DKDTYGQGLADATKAALAKRGVQDVMYEGLSRGEKDFNALVTKIGAQKPDVVFFGGCHPEAGPLVRQMREQGVQAKFFS- 250
Cdd:cd06337 154 PNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIVTGVMIPPDFATFWRQAAQQGFKPKVVTi 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 251 GDCIVNEEMVTAAGGPqytnGIYMTF---------GKDPRLIPDGKAVIEKFRAGKFEPEGYTL-YSYASVQAIAAAFKA 320
Cdd:cd06337 234 GKALLFPSAVAALGDL----GDGLSTevwwspahpFKSSLTGQTAAELADAYEKATGKQWTQPLgYAHALFEVAVDALKR 309
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 895889000 321 TGGKDSAKASEWLKANSVDTVMGKKAWDSKGDLKVSDYVVY--QW 363
Cdd:cd06337 310 AGSPDDEAVRAALADTDLDTIVGPVDFTSGPVPNVAKTPLVggQW 354
|
|
| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
94-248 |
5.69e-05 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 44.98 E-value: 5.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 94 DKVNAVVGHFCSSSTMPASEVYSDAGIITITPGSTNPLitergMSDM------FRMCGRDDQQGQVASDfIIDKLKAKRV 167
Cdd:cd06362 106 YDVVGVIGAESSSVSIQVANLLRLFKIPQISYASTSDE-----LSDKerypyfLRTVPSDSFQAKAIVD-ILLHFNWTYV 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 168 VIIHDKDTYGQGLADATKAALAKRGVQDVMYEGL--SRGEKDFNALVTKIgAQKPD----VVFFGGCHPEAgpLVRQMRE 241
Cdd:cd06362 180 SVVYSEGSYGEEGYKAFKKLARKAGICIAESERIsqDSDEKDYDDVIQKL-LQKKNarvvVLFADQEDIRG--LLRAAKR 256
|
....*..
gi 895889000 242 QGVQAKF 248
Cdd:cd06362 257 LGASGRF 263
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
30-205 |
1.97e-03 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 39.92 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 30 IGVAGPFTGPNATYGDQYWHGATQAA-EDINAAGGI-NGEKIKLVQGDDACEPKQAVavaNRLVD----QDKVNAVVGHF 103
Cdd:cd06366 2 IGGLFPLSGSKGWWGGAGILPAAEMAlEHINNRSDIlPGYNLELIWNDTQCDPGLGL---KALYDllytPPPKVMLLGPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895889000 104 CSSSTMPASEVYSDAGIITITPGSTNPLITERgmsDM----FRMCGRDDQQGQ--VAsdfIIDKLKAKRVVIIHDKDTYG 177
Cdd:cd06366 79 CSSVTEPVAEASKYWNLVQLSYAATSPALSDR---KRypyfFRTVPSDTAFNParIA---LLKHFGWKRVATIYQNDEVF 152
|
170 180
....*....|....*....|....*...
gi 895889000 178 QGLADATKAALAKRGVQDVMYEGLSRGE 205
Cdd:cd06366 153 SSTAEDLEELLEEANITIVATESFSSED 180
|
|
| |
