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Conserved domains on  [gi|872680109|ref|WP_048543212|]
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D-alanyl-D-alanine carboxypeptidase family protein [Bacillus wiedmannii]

Protein Classification

D-alanyl-D-alanine carboxypeptidase family protein( domain architecture ID 11447584)

D-alanyl-D-alanine carboxypeptidase family protein may remove C-terminal D-alanyl residues from sugar-peptide cell wall precursors

CATH:  3.40.710.10
EC:  3.4.-.-
Gene Ontology:  GO:0008236|GO:0006508
MEROPS:  S11
PubMed:  1741619|8439290|7845208
SCOP:  3001604

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DacC COG1686
D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];
60-313 4.92e-104

D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 441292 [Multi-domain]  Cd Length: 324  Bit Score: 307.15  E-value: 4.92e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQTEGARIPVQVNDTL 139
Cdd:COG1686   23 PPDIAAKSAILIDADTGQVLYEKNADERLPPASLTKLMTAYVVLEALKAGKISLDDKVTVSEEAARTGGSKMGLKPGEQV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 140 TVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDYaKFANASGLqepDGSETKMTAADVANLAYHLI 219
Cdd:COG1686  103 TVEDLLKGLLLQSGNDAAVALAEHIAGSEEAFVALMNAKAKELGMTNT-HFVNPTGL---PDPGHYSTARDLALLARAAI 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 220 KDYPEILEVTHLRQSQLA-FNNINVISTNDMLNKNnkalyiEGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVMGTKGK 298
Cdd:COG1686  179 KDYPEFYEIFSTKEFTFPnGRGITLRNTNRLLGRY------PGVDGLKTGYTDAAGYCLVASAKRGGRRLIAVVLGAPSE 252

                        250
                 ....*....|....*
gi 872680109 299 TQRFTETNKLMSYAF 313
Cdd:COG1686  253 KARFADAAKLLDYGF 267
 
Name Accession Description Interval E-value
DacC COG1686
D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];
60-313 4.92e-104

D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441292 [Multi-domain]  Cd Length: 324  Bit Score: 307.15  E-value: 4.92e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQTEGARIPVQVNDTL 139
Cdd:COG1686   23 PPDIAAKSAILIDADTGQVLYEKNADERLPPASLTKLMTAYVVLEALKAGKISLDDKVTVSEEAARTGGSKMGLKPGEQV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 140 TVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDYaKFANASGLqepDGSETKMTAADVANLAYHLI 219
Cdd:COG1686  103 TVEDLLKGLLLQSGNDAAVALAEHIAGSEEAFVALMNAKAKELGMTNT-HFVNPTGL---PDPGHYSTARDLALLARAAI 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 220 KDYPEILEVTHLRQSQLA-FNNINVISTNDMLNKNnkalyiEGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVMGTKGK 298
Cdd:COG1686  179 KDYPEFYEIFSTKEFTFPnGRGITLRNTNRLLGRY------PGVDGLKTGYTDAAGYCLVASAKRGGRRLIAVVLGAPSE 252

                        250
                 ....*....|....*
gi 872680109 299 TQRFTETNKLMSYAF 313
Cdd:COG1686  253 KARFADAAKLLDYGF 267
strep_PBP3 NF038273
streptococcal D-alanyl-D-alanine carboxypeptidase PBP3; PBP3 (penicillin-binding protein 3) is ...
 62-313 1.40e-70

streptococcal D-alanyl-D-alanine carboxypeptidase PBP3; PBP3 (penicillin-binding protein 3) is the lone D-alanyl-D-alanine carboxypeptidase in Streptococcus pneumoniae. The gene is known as pbp3 or dacA.


Pssm-ID: 468443 [Multi-domain]  Cd Length: 407  Bit Score: 224.36  E-value: 1.40e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  62 KIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQ----TEGARIPVQvND 137
Cdd:NF038273  25 DVAAKHAIAVEANTGKILYEKDATTPVPIASLTKLLTAYLVYKEIKSGKLSWDTPVKISDYPYElttnYEISNVPLD-AR 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 138 TLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGL------------QEPDgSETK 205
Cdd:NF038273 104 KYTVKELLEASLVASANSAAIALAEKIAGSEPKFVDKMKAQLKEWGITD-AKLVNASGLnnsylgdhiypgSKKD-DENK 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 206 MTAADVANLAYHLIKDYPEILEVThlRQSQLAFNNINVISTNDMLnkNNKALYIEGIDGLKTGFTDSAGYCFTGTAKQGD 285
Cdd:NF038273 182 LSAKDVAIIARHLIKDFPEVLKIT--SKTSADFAGTTIYSYNYML--KGMPYYREGVDGLKTGTTEKAGASFVATSVENG 257

                        250       260       270
                 ....*....|....*....|....*....|..
gi 872680109 286 TRIITVVMGTKGKTQ----RFTETNKLMSYAF 313
Cdd:NF038273 258 MRVITVVLNADNADEdeyaRFTATNQLLDYIY 289
Peptidase_S11 pfam00768
D-alanyl-D-alanine carboxypeptidase;
60-296 2.70e-67

D-alanyl-D-alanine carboxypeptidase;


Pssm-ID: 425859 [Multi-domain]  Cd Length: 234  Bit Score: 210.32  E-value: 2.70e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109   60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQTEG---ARIPVQVN 136
Cdd:pfam00768   3 APEIAAKSAILVDYNTGKVLYEKNPDQVRPIASITKLMTAYVVLEALKAGKIKEDDMVTISEDAWATGNpgsSNIFLKPG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  137 DTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDYaKFANASGLQEPDgseTKMTAADVANLAY 216
Cdd:pfam00768  83 SQVSVKDLLRGALVSSGNDAAVALAEHIAGSEKAFVK*MNAKAKELGLKNT-RFVNPTGLDAHG---QYSSARDMAILAK 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  217 HLIKDYPEILEVThlRQSQLAFNNINVI---STNDMLNKNNKalyieGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVM 293
Cdd:pfam00768 159 ALIKDLPEELSIT--KEKSFTFRGINKInqrNRNGLLWDKTW-----NVDGLKTGYTNEAGYCLVASATKGGMRLISVVM 231


                  ...
gi 872680109  294 GTK 296
Cdd:pfam00768 232 GAF 234
PBP4_Staph NF038258
penicillin-binding protein PBP4; Members of this family penicillin-binding protein 4 (PBP4), ...
 68-313 4.36e-45

penicillin-binding protein PBP4; Members of this family penicillin-binding protein 4 (PBP4), as the name is used in Staphylococcus aureus and related species from the same genus. PBP4 is not essential. It has transpeptidase activity, provides low level beta-lactam resistance, and in mutant strains can contribute to high level beta-lactam resistance.


Pssm-ID: 468436 [Multi-domain]  Cd Length: 365  Bit Score: 157.06  E-value: 4.36e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  68 AMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQT----EGARIPVQVNDTLTVKD 143
Cdd:NF038258  42 GAIVTTQTGQILYDYHGNKKWDPASMTKLMTMYLTLEAIKKGKLSLNDKVKITSDYEKMstlpNLSTFPLKPGQTYTIKE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 144 LYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASG-----LQE------PDGSETKMTAADVA 212
Cdd:NF038258 122 LLKQTALASSNAAALILAEKVSGNTSKFTDRMNEKAKALGMKH-THFTNPSGadnnlLKPyapkkyKDETKSKSTAKDMA 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 213 NLAYHLIKDYPEILEVTHLRQSQLafNNINVISTNDMLnkNNKALYIEGIDGLKTGFTDSaGYCFTGTAKQGDTRIITVV 292
Cdd:NF038258 201 ILSQHLIKKHPKILKYTKLTADTQ--HGVTLYTTNLSL--PGQPMSLKGTDGLKTGTSDE-GYNLALTTKRDGLRINQVI 275

                        250       260
                 ....*....|....*....|....*..
gi 872680109 293 MGTK------GKTQRFTETNKLMSYAF 313
Cdd:NF038258 276 MNVGpypsegAKHARNKIANALMERAF 302
PRK10001 PRK10001
serine-type D-Ala-D-Ala carboxypeptidase;
60-313 2.69e-44

serine-type D-Ala-D-Ala carboxypeptidase;


Pssm-ID: 182189 [Multi-domain]  Cd Length: 400  Bit Score: 155.92  E-value: 2.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQT-----EGARIP-V 133
Cdd:PRK10001  34 APSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATgnpalRGSSVMfL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 134 QVNDTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGLQEPDGSETkmtAADVAN 213
Cdd:PRK10001 114 KPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTN-TTFQTVHGLDAPGQFST---ARDMAL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 214 LAYHLIKDYPEilEVTHLRQSQLAFNNINVISTNDMLNKNNKalyieGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVM 293
Cdd:PRK10001 190 LGKALIHDVPE--EYAIHKEKEFTFNKIRQPNRNRLLWSSNL-----NVDGMKTGTTAGAGYNLVASATQGDMRLISVVL 262

                        250       260
                 ....*....|....*....|
gi 872680109 294 GTKGKTQRFTETNKLMSYAF 313
Cdd:PRK10001 263 GAKTDRIRFNESEKLLTWGF 282
 
Name Accession Description Interval E-value
DacC COG1686
D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];
60-313 4.92e-104

D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441292 [Multi-domain]  Cd Length: 324  Bit Score: 307.15  E-value: 4.92e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQTEGARIPVQVNDTL 139
Cdd:COG1686   23 PPDIAAKSAILIDADTGQVLYEKNADERLPPASLTKLMTAYVVLEALKAGKISLDDKVTVSEEAARTGGSKMGLKPGEQV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 140 TVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDYaKFANASGLqepDGSETKMTAADVANLAYHLI 219
Cdd:COG1686  103 TVEDLLKGLLLQSGNDAAVALAEHIAGSEEAFVALMNAKAKELGMTNT-HFVNPTGL---PDPGHYSTARDLALLARAAI 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 220 KDYPEILEVTHLRQSQLA-FNNINVISTNDMLNKNnkalyiEGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVMGTKGK 298
Cdd:COG1686  179 KDYPEFYEIFSTKEFTFPnGRGITLRNTNRLLGRY------PGVDGLKTGYTDAAGYCLVASAKRGGRRLIAVVLGAPSE 252

                        250
                 ....*....|....*
gi 872680109 299 TQRFTETNKLMSYAF 313
Cdd:COG1686  253 KARFADAAKLLDYGF 267
strep_PBP3 NF038273
streptococcal D-alanyl-D-alanine carboxypeptidase PBP3; PBP3 (penicillin-binding protein 3) is ...
 62-313 1.40e-70

streptococcal D-alanyl-D-alanine carboxypeptidase PBP3; PBP3 (penicillin-binding protein 3) is the lone D-alanyl-D-alanine carboxypeptidase in Streptococcus pneumoniae. The gene is known as pbp3 or dacA.


Pssm-ID: 468443 [Multi-domain]  Cd Length: 407  Bit Score: 224.36  E-value: 1.40e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  62 KIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQ----TEGARIPVQvND 137
Cdd:NF038273  25 DVAAKHAIAVEANTGKILYEKDATTPVPIASLTKLLTAYLVYKEIKSGKLSWDTPVKISDYPYElttnYEISNVPLD-AR 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 138 TLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGL------------QEPDgSETK 205
Cdd:NF038273 104 KYTVKELLEASLVASANSAAIALAEKIAGSEPKFVDKMKAQLKEWGITD-AKLVNASGLnnsylgdhiypgSKKD-DENK 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 206 MTAADVANLAYHLIKDYPEILEVThlRQSQLAFNNINVISTNDMLnkNNKALYIEGIDGLKTGFTDSAGYCFTGTAKQGD 285
Cdd:NF038273 182 LSAKDVAIIARHLIKDFPEVLKIT--SKTSADFAGTTIYSYNYML--KGMPYYREGVDGLKTGTTEKAGASFVATSVENG 257

                        250       260       270
                 ....*....|....*....|....*....|..
gi 872680109 286 TRIITVVMGTKGKTQ----RFTETNKLMSYAF 313
Cdd:NF038273 258 MRVITVVLNADNADEdeyaRFTATNQLLDYIY 289
Peptidase_S11 pfam00768
D-alanyl-D-alanine carboxypeptidase;
60-296 2.70e-67

D-alanyl-D-alanine carboxypeptidase;


Pssm-ID: 425859 [Multi-domain]  Cd Length: 234  Bit Score: 210.32  E-value: 2.70e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109   60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQTEG---ARIPVQVN 136
Cdd:pfam00768   3 APEIAAKSAILVDYNTGKVLYEKNPDQVRPIASITKLMTAYVVLEALKAGKIKEDDMVTISEDAWATGNpgsSNIFLKPG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  137 DTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDYaKFANASGLQEPDgseTKMTAADVANLAY 216
Cdd:pfam00768  83 SQVSVKDLLRGALVSSGNDAAVALAEHIAGSEKAFVK*MNAKAKELGLKNT-RFVNPTGLDAHG---QYSSARDMAILAK 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  217 HLIKDYPEILEVThlRQSQLAFNNINVI---STNDMLNKNNKalyieGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVM 293
Cdd:pfam00768 159 ALIKDLPEELSIT--KEKSFTFRGINKInqrNRNGLLWDKTW-----NVDGLKTGYTNEAGYCLVASATKGGMRLISVVM 231


                  ...
gi 872680109  294 GTK 296
Cdd:pfam00768 232 GAF 234
PBP4_Staph NF038258
penicillin-binding protein PBP4; Members of this family penicillin-binding protein 4 (PBP4), ...
 68-313 4.36e-45

penicillin-binding protein PBP4; Members of this family penicillin-binding protein 4 (PBP4), as the name is used in Staphylococcus aureus and related species from the same genus. PBP4 is not essential. It has transpeptidase activity, provides low level beta-lactam resistance, and in mutant strains can contribute to high level beta-lactam resistance.


Pssm-ID: 468436 [Multi-domain]  Cd Length: 365  Bit Score: 157.06  E-value: 4.36e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  68 AMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQT----EGARIPVQVNDTLTVKD 143
Cdd:NF038258  42 GAIVTTQTGQILYDYHGNKKWDPASMTKLMTMYLTLEAIKKGKLSLNDKVKITSDYEKMstlpNLSTFPLKPGQTYTIKE 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 144 LYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASG-----LQE------PDGSETKMTAADVA 212
Cdd:NF038258 122 LLKQTALASSNAAALILAEKVSGNTSKFTDRMNEKAKALGMKH-THFTNPSGadnnlLKPyapkkyKDETKSKSTAKDMA 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 213 NLAYHLIKDYPEILEVTHLRQSQLafNNINVISTNDMLnkNNKALYIEGIDGLKTGFTDSaGYCFTGTAKQGDTRIITVV 292
Cdd:NF038258 201 ILSQHLIKKHPKILKYTKLTADTQ--HGVTLYTTNLSL--PGQPMSLKGTDGLKTGTSDE-GYNLALTTKRDGLRINQVI 275

                        250       260
                 ....*....|....*....|....*..
gi 872680109 293 MGTK------GKTQRFTETNKLMSYAF 313
Cdd:NF038258 276 MNVGpypsegAKHARNKIANALMERAF 302
PRK10001 PRK10001
serine-type D-Ala-D-Ala carboxypeptidase;
60-313 2.69e-44

serine-type D-Ala-D-Ala carboxypeptidase;


Pssm-ID: 182189 [Multi-domain]  Cd Length: 400  Bit Score: 155.92  E-value: 2.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  60 PPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQT-----EGARIP-V 133
Cdd:PRK10001  34 APSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATgnpalRGSSVMfL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 134 QVNDTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGLQEPDGSETkmtAADVAN 213
Cdd:PRK10001 114 KPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTN-TTFQTVHGLDAPGQFST---ARDMAL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 214 LAYHLIKDYPEilEVTHLRQSQLAFNNINVISTNDMLNKNNKalyieGIDGLKTGFTDSAGYCFTGTAKQGDTRIITVVM 293
Cdd:PRK10001 190 LGKALIHDVPE--EYAIHKEKEFTFNKIRQPNRNRLLWSSNL-----NVDGMKTGTTAGAGYNLVASATQGDMRLISVVL 262

                        250       260
                 ....*....|....*....|
gi 872680109 294 GTKGKTQRFTETNKLMSYAF 313
Cdd:PRK10001 263 GAKTDRIRFNESEKLLTWGF 282
PRK10793 PRK10793
D-alanyl-D-alanine carboxypeptidase fraction A; Provisional
 59-313 9.79e-36

D-alanyl-D-alanine carboxypeptidase fraction A; Provisional


Pssm-ID: 182736 [Multi-domain]  Cd Length: 403  Bit Score: 133.06  E-value: 9.79e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  59 IP--PKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMSTKAAQT-----EGARI 131
Cdd:PRK10793  38 IPgvPQIDAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTVGNDAWATgnpvfKGSSL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 132 P-VQVNDTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGLqepDGSETKMTAAD 210
Cdd:PRK10793 118 MfLKPGMQVPVSQLIRGINLQSGNDACVAMADYVAGSQDAFVGLMNSYVNALGLKN-THFQTVHGL---DADGQYSSARD 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 211 VANLAYHLIKDYPEilEVTHLRQSQLAFNNINVISTNDMLNKNNKAlyiegIDGLKTGFTDSAGYCFTGTAKQGDTRIIT 290
Cdd:PRK10793 194 MALIGQALIRDVPN--EYAIYKEKEFTFNGIRQLNRNGLLWDNSLN-----VDGIKTGHTDKAGYNLVASATEGQMRLIS 266

                        250       260
                 ....*....|....*....|...
gi 872680109 291 VVMGTKGKTQRFTETNKLMSYAF 313
Cdd:PRK10793 267 AVMGGRTFKGRETESKKLLTWGF 289
dacD PRK11397
serine-type D-Ala-D-Ala carboxypeptidase DacD;
47-311 7.28e-35

serine-type D-Ala-D-Ala carboxypeptidase DacD;


Pssm-ID: 183117 [Multi-domain]  Cd Length: 388  Bit Score: 130.33  E-value: 7.28e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  47 TGLAEKVVPPKYIPPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMStKAAQT 126
Cdd:PRK11397  18 SAFAAENIPFSPQPPAIDAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVG-RDAWA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 127 EGAriPVQVN---------DTLTVKDLYHALMIESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGLQ 197
Cdd:PRK11397  97 KDN--PVFVGsslmflkegDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYVEKLHLKD-THFETVHGLD 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 198 EPdGSETkmTAADVANLAYHLIKDYPEILEVthLRQSQLAFNNINVISTNDMLnkNNKALYiegIDGLKTGFTDSAGYCF 277
Cdd:PRK11397 174 AP-GQHS--SAYDLAVLSRAIIHGEPEFYHM--YSEKSLTWNGITQQNRNGLL--WDKTMN---VDGLKTGHTSGAGFNL 243

                        250       260       270
                 ....*....|....*....|....*....|....
gi 872680109 278 TGTAKQGDTRIITVVMGTKGKTQRFTETNKLMSY 311
Cdd:PRK11397 244 IASAVDGQRRLIAVVMGADSAKGREEQARKLLRW 277
pbpG PRK11669
D-alanyl-D-alanine endopeptidase; Provisional
 44-308 1.45e-23

D-alanyl-D-alanine endopeptidase; Provisional


Pssm-ID: 236952  Cd Length: 306  Bit Score: 98.21  E-value: 1.45e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  44 LPKTGLAEKVVPPKYIPPKIDAKAAMIIDASNGEVIYQHNEKEAFAPASMSKMMTAYLLLEnvhnGKIRWEDPVKMS-TK 122
Cdd:PRK11669  20 APQAVAKTAAATTASQPQEIASGSAMVVDLNTNKVIYSSNPDLVVPIASITKLMTAMVVLD----AKLPLDEKLKVDiSQ 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 123 AAQTEGARIPVQVNDTLTVKDLYH-ALMiESANNSAVALAEHMAKTEKDFVQLMNAKAKELKMSDyAKFANASGLQEPDG 201
Cdd:PRK11669  96 TPEMKGVYSRVRLNSEISRKDMLLlALM-SSENRAAASLAHHYPGGYKAFIKAMNAKAKALGMTN-TRYVEPTGLSIHNV 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 202 SetkmTAADVANLayhLI--KDYPEILEVTHLRQSQLAFNNINVI----STNDMLNKNNkalyiEGIDGLKTGFTDSAGY 275
Cdd:PRK11669 174 S----TARDLTKL---LIasKQYPLIGQLSTTREKTATFRKPNYTlpfrNTNHLVYRDN-----WNIQLTKTGFTNAAGH 241

                        250       260       270
                 ....*....|....*....|....*....|...
gi 872680109 276 CFTGTAKQGDTRIITVVMGTKGKTQRFTETNKL 308
Cdd:PRK11669 242 CLVMRTVINNRPVALVVLDAFGKYTHFADASRL 274
Beta-lactamase2 pfam13354
Beta-lactamase enzyme family; This is the catalytic domain of class A beta-lactamases. It is ...
 70-221 1.79e-10

Beta-lactamase enzyme family; This is the catalytic domain of class A beta-lactamases. It is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.


Pssm-ID: 463854 [Multi-domain]  Cd Length: 215  Bit Score: 59.60  E-value: 1.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109   70 IIDASNGEVIyQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMsTKAAQTEGARI--PVQVNDTLTVKDLYHA 147
Cdd:pfam13354   4 VRDLDTGEEL-GINGDRSFPAASTIKVPILLAVLEQVDEGKLSLDERLTV-TAEDKVGGSGIlqYLPDGSQLSLRDLLTL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 872680109  148 LMIESANNSAVALAEHMAKTEkdfvqlMNAKAKELKMSDYAKFANASGLQEPDGSETKMT-AADVANLAYHLIKD 221
Cdd:pfam13354  82 MIAVSDNTATNLLIDRLGLEA------VNARLRALGLRDTRLRRKLPDLRAADKGGTNTTtARDMAKLLEALYRG 150
PenP COG2367
Beta-lactamase class A [Defense mechanisms];
70-214 9.04e-09

Beta-lactamase class A [Defense mechanisms];


Pssm-ID: 441934 [Multi-domain]  Cd Length: 276  Bit Score: 55.29  E-value: 9.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109  70 IIDASNGEVIyQHNEKEAFAPASMSKMMTAYLLLENVHNGKIRWEDPVKMsTKAAQTEGAriPV----QVNDTLTVKDLY 145
Cdd:COG2367   39 VLDLDTGETV-GINADERFPAASTFKLPVLAAVLRQVDAGKLSLDERVTL-TPEDLVGGS--GIlqklPDGTGLTLRELA 114

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872680109 146 HALMIESANNSAVALAEHMAKTEkdfvqlMNAKAKELKMSDYAKFANASGLQEPDGSET-KMTAADVANL 214
Cdd:COG2367  115 ELMITVSDNTATNLLLRLLGPDA------VNAFLRSLGLTDTRLDRKEPDLNELPGDGRnTTTPRDMARL 178
AmpC COG1680
CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
67-117 7.22e-04

CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];


Pssm-ID: 441286 [Multi-domain]  Cd Length: 355  Bit Score: 40.82  E-value: 7.22e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 872680109  67 AAMIIDasNGEVIYQH-------NEKEAFAP------ASMSKMMTAYLLLENVHNGKIRWEDPV 117
Cdd:COG1680   36 AVAVVR--DGKVVYEKaygvadlETGRPVTPdtlfriASVTKSFTATAVLQLVEEGKLDLDDPV 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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