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Conserved domains on  [gi|872670397|ref|WP_048541184|]
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MULTISPECIES: DUF485 domain-containing protein [Mammaliicoccus]

Protein Classification

DUF485 domain-containing protein( domain architecture ID 10006997)

DUF485 domain-containing protein similar to Escherichia coli inner membrane protein YjcH and Bacillus subtilis rotein YwcB

Gene Ontology:  GO:0016020
TCDB:  9.B.136

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-100 5.83e-19

Uncharacterized membrane protein, DUF485 family [Function unknown];


:

Pssm-ID: 442396  Cd Length: 104  Bit Score: 74.84  E-value: 5.83e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872670397   2 AEHDFKRLAADPKFKELLKKRNNFIFPISIFFIIATLLFPVLTGYT-NILNNIAFWNISWAWIYALLLFIMVWTLVTLYM 80
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFApGFLATPVGGVITVGIPLGLGQFVSTFVLTGIYV 83

                         90       100
                 ....*....|....*....|.
gi 872670397  81 RKA-KSFDKDAEELLKAYREE 100
Cdd:COG3162   84 RRAnREFDPLAEEIREEVEKG 104
 
Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-100 5.83e-19

Uncharacterized membrane protein, DUF485 family [Function unknown];


Pssm-ID: 442396  Cd Length: 104  Bit Score: 74.84  E-value: 5.83e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872670397   2 AEHDFKRLAADPKFKELLKKRNNFIFPISIFFIIATLLFPVLTGYT-NILNNIAFWNISWAWIYALLLFIMVWTLVTLYM 80
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFApGFLATPVGGVITVGIPLGLGQFVSTFVLTGIYV 83

                         90       100
                 ....*....|....*....|.
gi 872670397  81 RKA-KSFDKDAEELLKAYREE 100
Cdd:COG3162   84 RRAnREFDPLAEEIREEVEKG 104
DUF485 pfam04341
Protein of unknown function, DUF485; This family represents a putative component of ActP-like ...
 10-95 1.37e-12

Protein of unknown function, DUF485; This family represents a putative component of ActP-like carboxylate transporters. Several members are cofit with adjacent ActP-like permeases, and the family appears to represent a membrane protein. It has been suggested to be involved in pyruvate utilization.


Pssm-ID: 461268  Cd Length: 89  Bit Score: 57.86  E-value: 1.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872670397   10 AADPKFKELLKKRNNFIFPISIFFIIATLLFPVLTGYT-NILNN-IAFWNISWAWIYALLLFIMVWTLVTLYMRKA-KSF 86
Cdd:pfam04341   1 QASPKFQELVRRRRRFAWPLTAIFLVWYFGFVLLAAFApDFLATpVGEGVITVGIPLGLGQFVLTFLLTGIYVRRAnREF 80


                  ....*....
gi 872670397   87 DKDAEELLK 95
Cdd:pfam04341  81 DPLAEEIRE 89
 
Name Accession Description Interval E-value
YjcH COG3162
Uncharacterized membrane protein, DUF485 family [Function unknown];
2-100 5.83e-19

Uncharacterized membrane protein, DUF485 family [Function unknown];


Pssm-ID: 442396  Cd Length: 104  Bit Score: 74.84  E-value: 5.83e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872670397   2 AEHDFKRLAADPKFKELLKKRNNFIFPISIFFIIATLLFPVLTGYT-NILNNIAFWNISWAWIYALLLFIMVWTLVTLYM 80
Cdd:COG3162    4 PEEDYERIQASPEFQELVRRRRRFAFPLTAIFLVWYFGFILLIAFApGFLATPVGGVITVGIPLGLGQFVSTFVLTGIYV 83

                         90       100
                 ....*....|....*....|.
gi 872670397  81 RKA-KSFDKDAEELLKAYREE 100
Cdd:COG3162   84 RRAnREFDPLAEEIREEVEKG 104
DUF485 pfam04341
Protein of unknown function, DUF485; This family represents a putative component of ActP-like ...
 10-95 1.37e-12

Protein of unknown function, DUF485; This family represents a putative component of ActP-like carboxylate transporters. Several members are cofit with adjacent ActP-like permeases, and the family appears to represent a membrane protein. It has been suggested to be involved in pyruvate utilization.


Pssm-ID: 461268  Cd Length: 89  Bit Score: 57.86  E-value: 1.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872670397   10 AADPKFKELLKKRNNFIFPISIFFIIATLLFPVLTGYT-NILNN-IAFWNISWAWIYALLLFIMVWTLVTLYMRKA-KSF 86
Cdd:pfam04341   1 QASPKFQELVRRRRRFAWPLTAIFLVWYFGFVLLAAFApDFLATpVGEGVITVGIPLGLGQFVLTFLLTGIYVRRAnREF 80


                  ....*....
gi 872670397   87 DKDAEELLK 95
Cdd:pfam04341  81 DPLAEEIRE 89
COG5038 COG5038
Ca2+-dependent lipid-binding protein, contains C2 domain [General function prediction only];
53-103 1.24e-03

Ca2+-dependent lipid-binding protein, contains C2 domain [General function prediction only];


Pssm-ID: 227371 [Multi-domain]  Cd Length: 1227  Bit Score: 36.66  E-value: 1.24e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 872670397   53 IAFWNISWAWIYALLLFIMVWTLVTLYMRKAKSFDKDAEELLKAYREEQNL 103
Cdd:COG5038   166 VASWIFGYLGFSFASLFFIILVTMYVYRTCIKRVRRNIRDLVQQELSEEKL 216
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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