|
Name |
Accession |
Description |
Interval |
E-value |
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
165-430 |
7.05e-48 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 169.32 E-value: 7.05e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 165 ACAWISVRQVVRPFSqftravdSLDPAA--------STPMTEKGPLEVQRAAHAFNAMQARIQSYLRERAQILASISHDL 236
Cdd:PRK09467 168 AGGWLFIRIQNRPLV-------ALEHAAlqvgkgeiPPPLREYGASEVRSVTRAFNQMAAGIKQLEDDRTLLMAGVSHDL 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 237 QTPITRMKLRVEMAGEPE--LRDKLLNDLDSMTRLVREGIAYARSSEslEETPLKLELNAWVNSIACDYQDIGKNVQ--F 312
Cdd:PRK09467 241 RTPLTRIRLATEMMSEEDgyLAESINKDIEECNAIIEQFIDYLRTGQ--EMPMEMADLNALLGEVIAAESGYEREIEtaL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 313 QAGEARLPIvtRPQALRRVMTNLLDNALKFGEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNrdT 392
Cdd:PRK09467 319 QPGPIEVPM--NPIAIKRALANLVVNAARYGNGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARG--S 394
|
250 260 270
....*....|....*....|....*....|....*...
gi 835759819 393 GGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK09467 395 SGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLP 432
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
125-432 |
6.87e-45 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 158.92 E-value: 6.87e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 125 IQAHLTLRDGAPLTIDLIPRMPPVASWLPVVLILQLLLLGACAWISVRQVVRPFSQFTRAVDSLDPAASTPMTEKGPLEV 204
Cdd:COG0642 10 LLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 205 QRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRMKLRVEMA---GEPELR---DKLLNDLDSMTRLVREGIAYAR 278
Cdd:COG0642 90 LLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLleeLDEEQReylETILRSADRLLRLINDLLDLSR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 279 S-SESLEETPLKLELNAWVNSIACDYQDI--GKNVQF--QAGEARLPIVTRPQALRRVMTNLLDNALKFGEH-AVIAID- 351
Cdd:COG0642 170 LeAGKLELEPEPVDLAELLEEVVELFRPLaeEKGIELelDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEgGTVTVSv 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 352 NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNrdTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:COG0642 250 RREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRR--GGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPL 327
|
.
gi 835759819 432 R 432
Cdd:COG0642 328 A 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
217-432 |
1.27e-44 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 159.72 E-value: 1.27e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 217 RIQSYLRERAQILASISHDLQTPITRMKLRVEM-----AGEPELRDKLLN----DLDSMTRLVREGIAYARssesLEETP 287
Cdd:COG5002 157 ELERLEQMRREFVANVSHELRTPLTSIRGYLELlldgaADDPEERREYLEiileEAERLSRLVNDLLDLSR----LESGE 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 288 LKLE-----LNAWVNSIACDYQDIGKN----VQFQAGEARLPIVTRPQALRRVMTNLLDNALKFG-EHAVIAIDNSSSE- 356
Cdd:COG5002 233 LKLEkepvdLAELLEEVVEELRPLAEEkgieLELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTpEGGTITVSLREEDd 312
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 835759819 357 EVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:COG5002 313 QVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLA 388
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
210-432 |
4.23e-43 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 151.21 E-value: 4.23e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 210 AFNAMQARIQSYLRERAQILASISHDLQTPITRMKLRVEMAGE-----PELRDKLLNDLDS----MTRLVREGIAYAR-S 279
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDeedlsPEERRELLEIIREsaerLLRLIEDLLDLSRlE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 280 SESLEETPLKLELNAWVNSIACDYQDI----GKNVQFQAGEARLPIVTRPQALRRVMTNLLDNALKFG-EHAVIAID-NS 353
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLaeekGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSpPGGTITISaRR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 835759819 354 SSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNrdTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRG--EGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLA 237
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
195-430 |
4.60e-36 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 137.76 E-value: 4.60e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 195 PMTEKGPLEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRMKLRVEMA----GE-PELR---------DKLL 260
Cdd:PRK09470 213 PELETGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLATALLrrrqGEsKELErieteaqrlDSMI 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 261 NDLDSMTR------LVREGI-AYARSSESLEETPLKLELNawvnsiacdyqdiGKNVQFQAGEARLPIVTRPQALRRVMT 333
Cdd:PRK09470 293 NDLLVLSRnqqknhLERETFkANSLWSEVLEDAKFEAEQM-------------GKSLTVSAPPGPWPINGNPNALASALE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 334 NLLDNALKFGEHAV---IAIDNSsseEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLE 410
Cdd:PRK09470 360 NIVRNALRYSHTKIevaFSVDKD---GLTITVDDDGPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHR 436
|
250 260
....*....|....*....|.
gi 835759819 411 GKLNlTNRSG-GGLDVSITLP 430
Cdd:PRK09470 437 GWVK-AEDSPlGGLRLTIWLP 456
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
187-430 |
8.63e-30 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 120.09 E-value: 8.63e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 187 SLDPAAStpmtekgpleVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRMKLRVEMA---GEPElRDKLLNDL 263
Cdd:PRK10604 184 HFDEGSS----------LERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSdnlSAAE-SQALNRDI 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 264 DSMTRLVREGIAYARssesLE--ETPLKLE---LNAWVNSIACDYQDIGKNVQFQ---AGEArLPIVTRPQALRRVMTNL 335
Cdd:PRK10604 253 GQLEALIEELLTYAR----LDrpQNELHLSepdLPAWLSTHLADIQAVTPEKTVRldtPHQG-DYGALDMRLMERVLDNL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 336 LDNALKFGEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLEGKLNL 415
Cdd:PRK10604 328 LNNALRYAHSRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNC 407
|
250
....*....|....*
gi 835759819 416 TNRSGGGLDVSITLP 430
Cdd:PRK10604 408 DESELGGARFSFSWP 422
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
7.55e-29 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 108.95 E-value: 7.55e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFGeHAVIAIDNS-SSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLT 406
Cdd:cd16949 1 LARALENVLRNALRYS-PSKILLDISqDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERAI 79
|
90 100
....*....|....*....|....
gi 835759819 407 AQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16949 80 EQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
325-432 |
9.01e-28 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 106.19 E-value: 9.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKFG-EHAVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVEtSRNRDTGGTGLGLAIA 402
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTpEGGRITVTlERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLSIV 81
|
90 100 110
....*....|....*....|....*....|
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:smart00387 82 KKLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
9.25e-27 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 102.91 E-value: 9.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFGEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSrnRDTGGTGLGLAIAAQLTA 407
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNA--RGTSGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 835759819 408 QLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16950 79 AHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
328-429 |
4.43e-25 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 98.44 E-value: 4.43e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFG-EHAVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRdtGGTGLGLAIAAQL 405
Cdd:cd00075 1 LEQVLSNLLDNALKYSpPGGTIEISlRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREG--GGTGLGLAIVRRI 78
|
90 100
....*....|....*....|....
gi 835759819 406 TAQLEGKLNLTNRSGGGLDVSITL 429
Cdd:cd00075 79 VEAHGGRITVESEPGGGTTFTVTL 102
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
226-431 |
5.11e-25 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 106.20 E-value: 5.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 226 AQILASISHDLQTPIT---------RMKLRVEMAGEPELRDKLL----NDLDSMTRLVREGIAYARSSESleeTPLKLEL 292
Cdd:COG5000 202 GELARRIAHEIKNPLTpiqlsaerlRRKLADKLEEDREDLERALdtiiRQVDRLKRIVDEFLDFARLPEP---QLEPVDL 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 293 NAWVNSIACDYQD--IGKNVQF--QAGEARLPIVTRPQALRRVMTNLLDNALK-FGEHAVIAID-NSSSEEVVIHITDGG 366
Cdd:COG5000 279 NELLREVLALYEPalKEKDIRLelDLDPDLPEVLADRDQLEQVLINLLKNAIEaIEEGGEIEVStRREDGRVRIEVSDNG 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835759819 367 PGIPDDELEAVLQPFYrveTSRnrdTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:COG5000 359 PGIPEEVLERIFEPFF---TTK---PKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPL 417
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
325-432 |
9.03e-25 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 97.82 E-value: 9.03e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKF---GEHAVIAIDnsSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETsrnRDTGGTGLGLAI 401
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHaakAGEITVTLS--EGGELTLTVEDNGIGIPPEDLPRIFEPFSTADK---RGGGGTGLGLSI 77
|
90 100 110
....*....|....*....|....*....|.
gi 835759819 402 AAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:pfam02518 78 VRKLVELLGGTITVESEPGGGTTVTLTLPLA 108
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
167-401 |
1.47e-23 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 102.47 E-value: 1.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 167 AWISVRQVVRPFSQFTRAVDSLDP---AASTPMTEKgPLEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRM 243
Cdd:TIGR01386 181 GWWITRLGLEPLRRLSAVAARISPeslDQRLDPSRA-PAELRELAQSFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 244 KLRVEMA-----GEPELRDKL---LNDLDSMTRLVREGIAYARSSESLEETPL-KLELNAWVNSIACDYQ----DIGKNV 310
Cdd:TIGR01386 260 LGQTQVAlsqprTGEEYREVLesnLEELERLSRMVSDMLFLARADNGQLALERvRLDLAAELAKVAEYFEplaeERGVRI 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 311 QFQaGEARLPivTRPQALRRVMTNLLDNALKFG-EHAVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSR 388
Cdd:TIGR01386 340 RVE-GEGLVR--GDPQMFRRAISNLLSNALRHTpDGGTITVRiERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPAR 416
|
250
....*....|...
gi 835759819 389 NRDTGGTGLGLAI 401
Cdd:TIGR01386 417 SNSGEGTGLGLAI 429
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
328-430 |
3.27e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 93.71 E-value: 3.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKF---GE-HAVIAIDNSSSEEVVIHIT--DGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAI 401
Cdd:cd16922 1 LRQILLNLLGNAIKFteeGEvTLRVSLEEEEEDGVQLRFSveDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 835759819 402 AAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
107-431 |
3.41e-22 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 97.18 E-value: 3.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 107 LATQYPLSFTAVPGAVSHIQAHLTLRDGAPLTIDLIPRMPPVASWLPVVLILQLLLLGACAWISVRQVVRPFSQFTRAVD 186
Cdd:COG4191 22 LALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAAL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 187 SLDPAASTPMTEKGPLEVQRAAHAFNAMQAR-IQSylrER----AQILASISHDLQTPIT-------RMKLRVEMAGEPE 254
Cdd:COG4191 102 DAEENAELEELERDITELERAEEELRELQEQlVQS---EKlaalGELAAGIAHEINNPLAailgnaeLLRRRLEDEPDPE 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 255 LRDKLLNDLDS----MTRLVREGIAYARSSEsleETPLKLELNAWVNSIA------CDYQDIgkNVQFQAGEARLPIVTR 324
Cdd:COG4191 179 ELREALERILEgaerAAEIVRSLRAFSRRDE---EEREPVDLNELIDEALellrprLKARGI--EVELDLPPDLPPVLGD 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDN---ALKFGEHAVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYrveTSRnRDTGGTGLGLA 400
Cdd:COG4191 254 PGQLEQVLLNLLINaidAMEEGEGGRITIStRREGDYVVISVRDNGPGIPPEVLERIFEPFF---TTK-PVGKGTGLGLS 329
|
330 340 350
....*....|....*....|....*....|.
gi 835759819 401 IAAQLTAQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:COG4191 330 ISYGIVEKHGGRIEVESEPGGGTTFTITLPL 360
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
202-432 |
1.21e-21 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 97.16 E-value: 1.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 202 LEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRMKL---RVEMAGEPELRDKLLNDLDS-------MTRLVR 271
Cdd:COG4251 259 LELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKISGfsqLLEEDYGDKLDEEGREYLERirdaaerMQALID 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 272 EGIAYARSSeSLEETPLKLELNAWVNSIACDYQDI--GKNVQFQAGEarLPIV-TRPQALRRVMTNLLDNALKF---GEH 345
Cdd:COG4251 339 DLLAYSRVG-RQELEFEPVDLNELLEEVLEDLEPRieERGAEIEVGP--LPTVrGDPTLLRQVFQNLISNAIKYsrpGEP 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 346 AVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLD 424
Cdd:COG4251 416 PRIEIGaEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYE--GTGIGLAIVKKIVERHGGRIWVESEPGEGAT 493
|
....*...
gi 835759819 425 VSITLPRR 432
Cdd:COG4251 494 FYFTLPKA 501
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-430 |
2.77e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 85.59 E-value: 2.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKFGEHA-VIAIDNSSSEEVV-IHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIA 402
Cdd:cd16946 2 RDRLQQLFVNLLENSLRYTDTGgKLRIRAAQTPQEVrLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAIC 81
|
90 100
....*....|....*....|....*...
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16946 82 HNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
193-430 |
4.10e-20 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 92.00 E-value: 4.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 193 STPMTEKGPLEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITRMKLRVE----------------MAGEPELR 256
Cdd:PRK10549 208 TTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLAVLRGELEaiqdgvrkftpesvasLQAEVGTL 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 257 DKLLNDLDSMTRLVREGIAYARSSesLEETPLkLELNawVNSIACDYQDIGKNVQFQAGEaRLPIVTRPQALRRVMTNLL 336
Cdd:PRK10549 288 TKLVDDLHQLSLSDEGALAYRKTP--VDLVPL-LEVA--GGAFRERFASRGLTLQLSLPD-SATVFGDPDRLMQLFNNLL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 337 DNALKF----GEHAVIAidNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLEGK 412
Cdd:PRK10549 362 ENSLRYtdsgGSLHISA--EQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGR 439
|
250
....*....|....*...
gi 835759819 413 LNLTNRSGGGLDVSITLP 430
Cdd:PRK10549 440 IIAAHSPFGGVSITVELP 457
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
205-430 |
5.30e-19 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 89.71 E-value: 5.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 205 QRAAHAFNAMQARIQSylrERAQI----LASISHDLQTPITRMKLRVEM-------AGEP------ELRD------KLLN 261
Cdd:PRK10490 643 ERLTLTASEEQARLAS---EREQLrnalLAALSHDLRTPLTVLFGQAEIltldlasEGSPharqasEIRQqvlnttRLVN 719
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 262 DLDSMTRLVREGIAYARSSESLEET---------------PLKLELNAWVNSIACDyqdigknvqfqageARLpivtrpq 326
Cdd:PRK10490 720 NLLDMARIQSGGFNLRKEWLTLEEVvgsalqmlepglsghPINLSLPEPLTLIHVD--------------GPL------- 778
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 327 aLRRVMTNLLDNALKF-GEHAVIAIDNSSSEEVV-IHITDGGPGIPDDELEAVLQPFYRVetsrNRDTG--GTGLGLAIA 402
Cdd:PRK10490 779 -FERVLINLLENAVKYaGAQAEIGIDAHVEGERLqLDVWDNGPGIPPGQEQLIFDKFARG----NKESAipGVGLGLAIC 853
|
250 260
....*....|....*....|....*...
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK10490 854 RAIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
169-432 |
2.36e-18 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 87.13 E-value: 2.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 169 ISVRQVVRPFSQFTRAVDS---------LDPAAStpmtekgPLEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTP 239
Cdd:PRK09835 204 LAVHKGHAPIRSVSRQIQNitskdldvrLDPQTV-------PIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 240 ITRMKLRVEMA-----GEPELRDKL---LNDLDSMTRLVREGIAYARSSES---LEETPLKLE---------LNAWVNSI 299
Cdd:PRK09835 277 ITNLITQTEIAlsqsrSQKELEDVLysnLEELTRMAKMVSDMLFLAQADNNqliPEKKMLDLAdevgkvfdfFEAWAEER 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 300 ACDYQDIGKNVQfqagearlpIVTRPQALRRVMTNLLDNALKFGE--HAVIAIDNSSSEEVVIHITDGGPGIPDDELEAV 377
Cdd:PRK09835 357 GVELRFVGDPCQ---------VAGDPLMLRRAISNLLSNALRYTPagEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRL 427
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 835759819 378 LQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLEGKLNLTNrSGGGLDVSITLPRR 432
Cdd:PRK09835 428 FDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTS-DARGTRFVISLPRL 481
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
176-428 |
4.23e-18 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 85.86 E-value: 4.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 176 RPFSQFTRAVDSLDPAASTPMTEKG-PLEVQRAAHAFNAMQARIQSYL-RERaQILASISHDLQTPITRMKLRVEMA--- 250
Cdd:PRK10337 187 APLKKLALALRMRDPDSETPLNATGvPSEVRPLVEALNQLFARTHAMMvRER-RFTSDAAHELRSPLAALKVQTEVAqls 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 251 -GEPELRDKLLNDLDS----MTRLVREGIAYAR--SSESLEET-PLKLE--LNAWVNSIACDYQDIGKNVQFQAGEArlP 320
Cdd:PRK10337 266 dDDPQARKKALLQLHAgidrATRLVDQLLTLSRldSLDNLQDVaEIPLEdlLQSAVMDIYHTAQQAGIDVRLTLNAH--P 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 321 IVTRPQAL--RRVMTNLLDNALKF---GEHAVIAIDNSSseevvIHITDGGPGIPDDELEAVLQPFYRvetSRNRDTGGT 395
Cdd:PRK10337 344 VIRTGQPLllSLLVRNLLDNAIRYspqGSVVDVTLNARN-----FTVRDNGPGVTPEALARIGERFYR---PPGQEATGS 415
|
250 260 270
....*....|....*....|....*....|....
gi 835759819 396 GLGLAIAAQLtAQLEG-KLNLTNRSGGGLDVSIT 428
Cdd:PRK10337 416 GLGLSIVRRI-AKLHGmNVSFGNAPEGGFEAKVS 448
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-429 |
4.26e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 79.37 E-value: 4.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKF-GEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRvetSRNRDTGGTGLGLAIAAQLT 406
Cdd:cd16940 14 LFLLLRNLVDNAVRYsPQGSRVEIKLSADDGAVIRVEDNGPGIDEEELEALFERFYR---SDGQNYGGSGLGLSIVKRIV 90
|
90 100
....*....|....*....|...
gi 835759819 407 AQLEGKLNLTNRSGGGLDVSITL 429
Cdd:cd16940 91 ELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
225-432 |
3.85e-17 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 83.14 E-value: 3.85e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 225 RAQILASISHDLQTPITRMKLRVEMAGEPEL----RDKLLNDLDSMTR----LVREGIAYARSSES----LEET---PLK 289
Cdd:PRK11006 204 RRNFFANVSHELRTPLTVLQGYLEMMQDQPLegalREKALHTMREQTQrmegLVKQLLTLSKIEAAptidLNEKvdvPMM 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 290 LE-LNAWVNSIACDYQDIGKNVqfqagEARLPIVTRPQALRRVMTNLLDNALKFG-EHAVIAID-NSSSEEVVIHITDGG 366
Cdd:PRK11006 284 LRvLEREAQTLSQGKHTITFEV-----DNSLKVFGNEDQLRSAISNLVYNAVNHTpEGTHITVRwQRVPQGAEFSVEDNG 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 835759819 367 PGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:PRK11006 359 PGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLPER 424
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-431 |
2.14e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 74.39 E-value: 2.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFGEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQLTA 407
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVAL 80
|
90 100
....*....|....*....|....
gi 835759819 408 QLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:cd16939 81 WHGGHVECDDSELGGACFRLTWPR 104
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
164-432 |
4.86e-16 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 79.89 E-value: 4.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 164 GACAWIsvrqVVRPFSQFTRAVDSLDPAASTPMTEKGPLEVQRAAHAFNAMQAR------IQSYLReraqilaSISHDLQ 237
Cdd:PRK11100 200 AGVVWW----LNRSIRRLTRYADAVTEGKPVPLPKLGSSELRELAQALESMRVKlegkayVEQYVQ-------TLTHELK 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 238 TPITRMK-----LRVEMAgePELRDKLLNDLDS----MTRLVREGIAYARssesLE-----ETPLKLELNAWVNSIACDY 303
Cdd:PRK11100 269 SPLAAIRgaaelLQEDPP--PEDRARFTGNILTqsarLQQLIDRLLELAR----LEqrqelEVLEPVALAALLEELVEAR 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 304 QDI--GKNVQFQAGEARLPIVTRPQALRRVMTNLLDNALKFG-EHAVIAIDNS-SSEEVVIHITDGGPGIPDDELEAVLQ 379
Cdd:PRK11100 343 EAQaaAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSpEGGTITLSAEvDGEQVALSVEDQGPGIPDYALPRIFE 422
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 835759819 380 PFY---RVETSRNrdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:PRK11100 423 RFYslpRPANGRK----STGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRH 474
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
168-432 |
1.16e-15 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 77.70 E-value: 1.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 168 WISVRQVVRPFSQF-----TRAVDSLDPAASTPMTEkgplEVQRAAHAFNAMQARIQSYLRERAQILASISHDLQTPITR 242
Cdd:PRK10755 79 FQAVRWITRPLAELqkeleARTADNLTPIAIHSSTL----EIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAG 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 243 MKLRVEM---AGEPELrDKLLNDLDSMTRLVREGIAYARSSESLEE-------------TPLKLELNAWVnsiacdyQDI 306
Cdd:PRK10755 155 IRLHLELlekQHHIDV-APLIARLDQMMHTVEQLLQLARAGQSFSSghyqtvklledviLPSQDELSEML-------EQR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 307 GKNVQFQAGEARLPIVTRPQALRRVMTNLLDNALKFG-EHAVIAIDNSSSEE-VVIHITDGGPGIPDDELEAVLQPFYRV 384
Cdd:PRK10755 227 QQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSpEGSTITIKLSQEDGgAVLAVEDEGPGIDESKCGELSKAFVRM 306
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 835759819 385 ETSrnrdTGGTGLGLAIAAQLTAQLEGKLNLTNRS-GGGLDVSITLPRR 432
Cdd:PRK10755 307 DSR----YGGIGLGLSIVSRITQLHHGQFFLQNRQeRSGTRAWVWLPKA 351
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
213-401 |
1.23e-15 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 78.07 E-value: 1.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 213 AMQARIQSylreRAQILASISHDLQTPITRMKLRVE----------MAGEPELRDKLL----NDLDSMTRLVREGIAYAR 278
Cdd:PRK09303 143 TLLEQLKF----KDRVLAMLAHDLRTPLTAASLALEtlelgqidedTELKPALIEQLQdqarRQLEEIERLITDLLEVGR 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 279 SS-ESLEETPLKLELNAWVNSIACDYQDI--GKNVQFQAG-EARLPIV-TRPQALRRVMTNLLDNALKF---GEHAVIAI 350
Cdd:PRK09303 219 TRwEALRFNPQKLDLGSLCQEVILELEKRwlAKSLEIQTDiPSDLPSVyADQERIRQVLLNLLDNAIKYtpeGGTITLSM 298
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 835759819 351 DNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVetSRNRDTGGTGLGLAI 401
Cdd:PRK09303 299 LHRTTQKVQVSICDTGPGIPEEEQERIFEDRVRL--PRDEGTEGYGIGLSV 347
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
168-430 |
1.60e-15 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 78.92 E-value: 1.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 168 WISVRQVVRPFSQFTRAVDSLDPAA-STPMTEKGPLEVQRAAHAFNAMQARIQSYLR-------ERAQILA--------- 230
Cdd:PRK15347 315 LLLRRYLAKPLWRFVDIINKTGPAAlEPRLPENRLDELGSIAKAYNQLLDTLNEQYDtlenkvaERTQALAeakqraeqa 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 231 ---------SISHDLQTPITRMKLRVEM-------AGEPELRDKLLNDLDSMTRLVREGIAYAR-----SSESLEETPLK 289
Cdd:PRK15347 395 nkrksehltTISHEIRTPLNGVLGALELlqntpltAEQMDLADTARQCTLSLLAIINNLLDFSRiesgqMTLSLEETALL 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 290 LELNAWVNSIACDYQDIGKNVQ-FQAGEARLPIVTRPQALRRVMTNLLDNALKFGEHAVIAIDNSSSEEVVI-HITDGGP 367
Cdd:PRK15347 475 PLLDQAMLTIQGPAQSKSLTLRtFVGAHVPLYLHLDSLRLRQILVNLLGNAVKFTETGGIRLRVKRHEQQLCfTVEDTGC 554
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 835759819 368 GIPDDELEAVLQPFYRVETSRnrdtGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK15347 555 GIDIQQQQQIFTPFYQADTHS----QGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
303-429 |
4.11e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 71.89 E-value: 4.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 303 YQDigKNVQFQAG---EARLPIvtRPQALRRVMTNLLDNALKFGEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQ 379
Cdd:cd16954 14 YQR--KGVSISLDispELRFPG--ERNDLMELLGNLLDNACKWCLEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQ 89
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 835759819 380 PFYRVETSRNrdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITL 429
Cdd:cd16954 90 RGQRLDEQRP----GQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
215-432 |
6.08e-15 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 76.93 E-value: 6.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 215 QARIQSYLR--ERAQIL----ASISHDLQTPITRMKLRVEM----AGEPELRDKL---LNDLDSMTRLVREGIAYARSSE 281
Cdd:PRK11360 374 RKRLQRRVArqERLAALgelvAGVAHEIRNPLTAIRGYVQIwrqqTSDPPSQEYLsvvLREVDRLNKVIDQLLEFSRPRE 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 282 SleeTPLKLELNAWVNSIACDYQDIGK--NVQFQ-AGEARLP-IVTRPQALRRVMTNLLDNALK-FGEHAVIAID--NSS 354
Cdd:PRK11360 454 S---QWQPVSLNALVEEVLQLFQTAGVqaRVDFEtELDNELPpIWADPELLKQVLLNILINAVQaISARGKIRIRtwQYS 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835759819 355 SEEVVIHITDGGPGIPDDELEAVLQPFYrveTSRNRdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:PRK11360 531 DGQVAVSIEDNGCGIDPELLKKIFDPFF---TTKAK---GTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLPIN 602
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
326-418 |
1.48e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 69.85 E-value: 1.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 326 QALRRVMTNLLDNALKFGEHA-VIAIDNSSSEE-VVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAA 403
Cdd:cd16947 19 EALQRILKNLISNAIKYGSDGkFLGMTLREDEKhVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQGNGLGLTITK 98
|
90
....*....|....*
gi 835759819 404 QLTAQLEGKLNLTNR 418
Cdd:cd16947 99 RLAESMGGSIYVNSK 113
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
227-430 |
1.78e-14 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 75.01 E-value: 1.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 227 QILASISHDLQTPITRMK----LRVEMAGEPELR--DKLLNDLDSMTRLVREGIAYAR-SSESLEETPLklelNAWVNSI 299
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKgfiqLLKDTIDEEQKTylDIMLSELDRIESIISEFLVLAKpQAIKYEPKDL----NTLIEEV 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 300 A--CDYQDIGKNVQFQ-AGEARLP-IVTRPQALRRVMTNLLDNALKF---GEHAVIAIDNSSSEEVVIHITDGGPGIPDD 372
Cdd:COG5809 348 IplLQPQALLKNVQIElELEDDIPdILGDENQLKQVFINLLKNAIEAmpeGGNITIETKAEDDDKVVISVTDEGCGIPEE 427
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 835759819 373 ELEAVLQPFYrvetsrNRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:COG5809 428 RLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLP 479
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-414 |
2.79e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 68.57 E-value: 2.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFG-EHAVIAIDNSSSEEVV-IHITDGGPGIPDDELEAVLQPFYRVETSRNrdTGGTGLGLAIAAQL 405
Cdd:cd16923 1 LQRVFSNLLSNAIKYSpENTRIYITSFLTDDVVnIMFKNPSSHPLDFKLEKLFERFYRGDNSRN--TEGAGLGLSIAKAI 78
|
....*....
gi 835759819 406 TAQLEGKLN 414
Cdd:cd16923 79 IELHGGSAS 87
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
325-430 |
4.71e-14 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 67.90 E-value: 4.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKF---GEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAI 401
Cdd:cd16925 2 AEKYERVVLNLLSNAFKFtpdGGRIRCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSI 81
|
90 100
....*....|....*....|....*....
gi 835759819 402 AAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16925 82 VKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-424 |
1.06e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 67.10 E-value: 1.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKFG-EHAVIAID-NSSSEEVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGgTGLGLAIA 402
Cdd:cd16945 2 PFLLRQAINNLLDNAIDFSpEGGLIALQlEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQKS-TGLGLAFV 80
|
90 100
....*....|....*....|..
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLD 424
Cdd:cd16945 81 QEVAQLHGGRITLRNRPDGVLA 102
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
325-432 |
2.55e-13 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 72.25 E-value: 2.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKFGEHAVIAIDNSSSEEV-VIHITDGGPGIPDDELEAVLQPFYRVETSRnrdtGGTGLGLAIAA 403
Cdd:PRK11466 559 PRRIRQVITNLLSNALRFTDEGSIVLRSRTDGEQwLVEVEDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISS 634
|
90 100
....*....|....*....|....*....
gi 835759819 404 QLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:PRK11466 635 RLAQAMGGELSATSTPEVGSCFCLRLPLR 663
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
2.77e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 65.81 E-value: 2.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKF---GEHAVIAIDNS-SSEEVVIHITDGGPGIPDDELEAVLQPFYRVETsrNRDTGGTGLGLAIAA 403
Cdd:cd16921 1 LGQVLTNLLGNAIKFrrpRRPPRIEVGAEdVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHS--REEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 835759819 404 QLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-432 |
4.15e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 65.30 E-value: 4.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFG-EHAVIAIDNSSSEE-VVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAAQL 405
Cdd:cd16952 1 LRSAFSNLVSNAVKYTpPSDTITVRWSQEESgARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*..
gi 835759819 406 TAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:cd16952 81 MSRHDARLLIASELGKGSRFTCLFPSS 107
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
214-432 |
9.52e-13 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 69.10 E-value: 9.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 214 MQARIQSYLRERAQ------ILASISHDLQTPIT-------RMKLRVEMAGEPELRDKLLNDLDSMTRLVREGIAYARSS 280
Cdd:COG3852 118 ERKRLERELRRAEKlaavgeLAAGLAHEIRNPLTgirgaaqLLERELPDDELREYTQLIIEEADRLNNLVDRLLSFSRPR 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 281 ESLEETplkLELNAWVN---SIACdyQDIGKNVQFQAG-EARLPIVT-RPQALRRVMTNLLDNAL----KFGE------- 344
Cdd:COG3852 198 PPEREP---VNLHEVLErvlELLR--AEAPKNIRIVRDyDPSLPEVLgDPDQLIQVLLNLVRNAAeampEGGTitirtrv 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 345 -HAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYrveTSRnrdTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGL 423
Cdd:COG3852 273 eRQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFF---TTK---EKGTGLGLAIVQKIVEQHGGTIEVESEPGKGT 346
|
....*....
gi 835759819 424 DVSITLPRR 432
Cdd:COG3852 347 TFRIYLPLE 355
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
230-430 |
1.51e-12 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 69.04 E-value: 1.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 230 ASISHDLQTPITRMK-------LRVEMAGEP-ELRDKLLNDLDSMTRLVREGIAYARSSE-SLEETPLKLELNAWVNSIA 300
Cdd:PRK10364 242 AGVAHEIRNPLSSIKglakyfaERAPAGGEAhQLAQVMAKEADRLNRVVSELLELVKPTHlALQAVDLNDLINHSLQLVS 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 301 CDYQDIGKNVQFQAGEARLPIVTRPQALRRVMTNLLDNALK-FGEHAVIAIDNS-SSEEVVIHITDGGPGIPDDELEAVL 378
Cdd:PRK10364 322 QDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQaIGQHGVISVTASeSGAGVKISVTDSGKGIAADQLEAIF 401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 835759819 379 QPFYrveTSRNRdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK10364 402 TPYF---TTKAE---GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
202-430 |
2.22e-12 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 69.38 E-value: 2.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 202 LEVQRAaHAFNAMQARiqsylrerAQILASISHDLQTPITRMKLRVEM-AGEPELRDKLLNDLD-------SMTRLVREG 273
Cdd:PRK09959 698 LEVERN-KAINATVAK--------SQFLATMSHEIRTPISSIMGFLELlSGSGLSKEQRVEAISlayatgqSLLGLIGEI 768
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 274 IAYAR-SSESLEETPLKLELNAWVNSIACDYQDIGKNVQFQ-AGEARLP----IVTRPQALRRVMTNLLDNALKFGEHAV 347
Cdd:PRK09959 769 LDVDKiESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIAlSCSSTFPdhylVKIDPQAFKQVLSNLLSNALKFTTEGA 848
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 348 IAIDNS----SSEEVVIHIT--DGGPGIPDDELEAVLQPFyrVETSRNRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGG 421
Cdd:PRK09959 849 VKITTSlghiDDNHAVIKMTimDSGSGLSQEEQQQLFKRY--SQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGI 926
|
....*....
gi 835759819 422 GLDVSITLP 430
Cdd:PRK09959 927 GTTFTITIP 935
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
325-432 |
2.42e-12 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 67.95 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALkfgeHAVIAIDNS----------SSEEVVIHITDGGPGIPDDELEAVLQPfyRVETsrnRDTGG 394
Cdd:COG3290 279 DTDLVTILGNLLDNAI----EAVEKLPEEerrvelsirdDGDELVIEVEDSGPGIPEELLEKIFER--GFST---KLGEG 349
|
90 100 110
....*....|....*....|....*....|....*...
gi 835759819 395 TGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:COG3290 350 RGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPKE 387
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
223-431 |
7.51e-12 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 67.27 E-value: 7.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 223 RERAQILASISHDLQTPI------TRMKLRVEMAGEPELRDK-----------LLNDLDSMTRLVREgiayarsseSLEE 285
Cdd:PRK11091 281 RDKTTFISTISHELRTPLngivglSRILLDTELTAEQRKYLKtihvsaitlgnIFNDIIDMDKMERR---------KLQL 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 286 TPLKLELNAWVNsiacDYQDIGKNVQFQAG-----EARLP----IVTRPQALRRVMTNLLDNALKFGEHAVIAIDNSSSE 356
Cdd:PRK11091 352 DNQPIDFTDFLA----DLENLSGLQAEQKGlrfdlEPLLPlphkVITDGTRLRQILWNLISNAVKFTQQGGVTVRVRYEE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 357 EVVIH--ITDGGPGIPDDELEAVLQPFYRVETSR-NRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGG--LDVSITLPR 431
Cdd:PRK11091 428 GDMLTfeVEDSGIGIPEDELDKIFAMYYQVKDSHgGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKGscFTLTIHAPA 507
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-430 |
1.15e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 61.40 E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 327 ALRRVMTNLLDNALKFGE-------HAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYrveTSRNRdtgGTGLGL 399
Cdd:cd16944 4 QISQVLTNILKNAAEAIEgrpsdvgEVRIRVEADQDGRIVLIVCDNGKGFPREMRHRATEPYV---TTRPK---GTGLGL 77
|
90 100 110
....*....|....*....|....*....|.
gi 835759819 400 AIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16944 78 AIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
325-431 |
1.19e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 60.90 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALK-FGEHAVIAIDNS-SSEEVVIHITDGGPGIPDDELEAVLQPFYrveTSRNRDTGgTGLGLAIA 402
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQaMEGRGRITIRTWaHVDQVLIEVEDTGSGIDPEILGRIFDPFF---TTKPVGEG-TGLGLSLS 76
|
90 100
....*....|....*....|....*....
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-429 |
1.57e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 60.55 E-value: 1.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNAL-KFGEHAVIAIDNSSSEE---VVIHITDGGPGIPDDELEAVLQPFYrvetsRNRDTG-GTGLGLAIA 402
Cdd:cd16976 1 IQQVLMNLLQNALdAMGKVENPRIRIAARRLggrLVLVVRDNGPGIAEEHLSRVFDPFF-----TTKPVGkGTGLGLSIS 75
|
90 100
....*....|....*....|....*..
gi 835759819 403 AQLTAQLEGKLNLTNRSGGGLDVSITL 429
Cdd:cd16976 76 YGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
327-430 |
3.14e-11 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 65.64 E-value: 3.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 327 ALR--RVMTNLLDNALKFGEHAVIAID---NSSSEEVV---IHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLG 398
Cdd:PRK11107 406 PLRlqQIITNLVGNAIKFTESGNIDILvelRALSNTKVqleVQIRDTGIGISERQQSQLFQAFRQADASISRRHGGTGLG 485
|
90 100 110
....*....|....*....|....*....|..
gi 835759819 399 LAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK11107 486 LVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
331-431 |
4.72e-11 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 64.27 E-value: 4.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 331 VMTNLLDNA----LKFGEHAVIAIDNSsseeVVIHITDGGPGIPDDELEAVLQPFYRVETSRNrdtgGTGLGLAIAAQLT 406
Cdd:PRK10815 382 VMGNVLDNAckycLEFVEISARQTDEH----LHIVVEDDGPGIPESKRELIFDRGQRADTLRP----GQGLGLSVAREIT 453
|
90 100
....*....|....*....|....*
gi 835759819 407 AQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:PRK10815 454 EQYEGKISAGDSPLGGARMEVIFGR 478
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
227-430 |
2.91e-10 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 62.06 E-value: 2.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 227 QILASISHDLQTPITRMK-----LRVEMAGEPELRDKLLNDLDSMTRLVREGIAYAR-SSESLEETPLKLELNAWVNSIA 300
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKgflqlLQPGIEDKEEYFDIMLSELDRIESIISEFLALAKpQAVNKEKENINELIQDVVTLLE 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 301 CDYQDIGKNVQFQAGEARLPIVTRPQALRRVMTNLLDNALKfgehaviAIDN---------SSSEEVVIHITDGGPGIPD 371
Cdd:COG5805 369 TEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIE-------AMPNggtitihteEEDNSVIIRVIDEGIGIPE 441
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 835759819 372 DELEAVLQPFYRVETSrnrdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:COG5805 442 ERLKKLGEPFFTTKEK------GTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLP 494
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
167-432 |
3.73e-10 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 61.57 E-value: 3.73e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 167 AWISVRQVVRPFSQFTRAVDSLDPAASTPMTEKGPLEVQRAAHAFNAMQARIQSYLRERAQILASIS------------- 233
Cdd:COG2972 174 SYLLSRSITRPIKRLKKAMKKVEKGDLVRLEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKeaelkalqaqinp 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 234 HDLQTPITRMKLRVEMAGEPELRDkLLNDLdsmTRLVREGIayarsSESLEETPLKLELNawvnsIACDYQDI-----GK 308
Cdd:COG2972 254 HFLFNTLNSIRWLAELEDPEEAEE-MLEAL---SKLLRYSL-----SKGDELVTLEEELE-----LIKSYLEIqklrfGD 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 309 NVQFQ------AGEARLPivtrpqalRRVMTNLLDNALKFG-----EHAVIAID-NSSSEEVVIHITDGGPGIPDDELEA 376
Cdd:COG2972 320 RLEVEieideeLLDLLIP--------KLILQPLVENAIEHGiepkeGGGTIRISiRKEGDRLVITVEDNGVGMPEEKLEK 391
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 835759819 377 VLQPFyrvetsrNRDTGGTGLGLAIAAQLTAQLEGK---LNLTNRSGGGLDVSITLPRR 432
Cdd:COG2972 392 LLEEL-------SSKGEGRGIGLRNVRERLKLYYGEeygLEIESEPGEGTTVTIRIPLE 443
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
325-430 |
1.66e-09 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 59.99 E-value: 1.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKFGEHAVIAIDNSSSEE-VVIHITDGGPGIPDDELEAVLQPFYRVETSRNRDTGGTGLGLAIAA 403
Cdd:PRK10841 560 PMRLQQVISNLLSNAIKFTDTGCIVLHVRVDGDyLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICE 639
|
90 100
....*....|....*....|....*..
gi 835759819 404 QLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK10841 640 KLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
334-430 |
3.27e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 54.22 E-value: 3.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 334 NLLDNALKfgehAVIAIDNSSSE----------EVVIHITDGGPGIPDDELEAVLQPFYRVETSRNRdtggtGLGLAIAA 403
Cdd:cd16915 7 NLIDNALD----ALAATGAPNKQvevflrdegdDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGER-----GIGLALVR 77
|
90 100
....*....|....*....|....*..
gi 835759819 404 QLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16915 78 QSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
6.35e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 53.17 E-value: 6.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALK-----FGEHAVIAIDNSSSE--EVVIHITDGGPGIPDDELEAVLQPFYRVETSrnrdtgGTGLGLA 400
Cdd:cd16920 1 IQQVLINLVRNGIEamsegGCERRELTIRTSPADdrAVTISVKDTGPGIAEEVAGQLFDPFYTTKSE------GLGMGLS 74
|
90 100 110
....*....|....*....|....*....|
gi 835759819 401 IAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16920 75 ICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
326-427 |
7.76e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 53.23 E-value: 7.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 326 QALRRVMTNLLDNALKFG-EHAVIAIDNSSSEEVV-IHITDGGPGIPDDELEAVLQPFYRVETSRNRDtGGTGLGLAIAA 403
Cdd:cd16975 3 LLLSRALINIISNACQYApEGGTVSISIYDEEEYLyFEIWDNGHGFSEQDLKKALELFYRDDTSRRSG-GHYGMGLYIAK 81
|
90 100
....*....|....*....|....
gi 835759819 404 QLTAQLEGKLNLTNRSGGGLDVSI 427
Cdd:cd16975 82 NLVEKHGGSLIIENSQKGGAEVTV 105
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
1.34e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 52.40 E-value: 1.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKF--GEHAVIAIDNSSSEEVVI-----------HITDGGPGIPDDELEAVLQPFYrveTSRnrdTGG 394
Cdd:cd16918 1 LIQVFLNLVRNAAQAlaGSGGEIILRTRTQRQVTLghprhrlalrvSVIDNGPGIPPDLQDTIFYPMV---SGR---ENG 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 835759819 395 TGLGLAIAAQLTAQLEGKLNLTNRSgGGLDVSITLP 430
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECDSQP-GHTVFSVSLP 109
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-419 |
1.03e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 49.88 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKFGEHAVIAIDNSSSEE---VVIHITDGGPGIPDDELEAVLQPFYrVETSRNRDTG-GTGLGLAIAA 403
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTGRITVSAMPTgkmVTISVEDEGPGIPQEKLESIFDRFY-TERPANEAFGqHSGLGLSISR 79
|
90
....*....|....*.
gi 835759819 404 QLTAQLEGKLNLTNRS 419
Cdd:cd16953 80 QIIEAHGGISVAENHN 95
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
325-432 |
1.45e-07 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 53.16 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 325 PQALRRVMTNLLDNALKF--GEHAVIAIDNSSSEEVVIH-----------ITDGGPGIPDdELEAVLqpFYRVETSRNrd 391
Cdd:PRK11073 235 PDQIEQVLLNIVRNALQAlgPEGGTITLRTRTAFQLTLHgeryrlaaridIEDNGPGIPP-HLQDTL--FYPMVSGRE-- 309
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 835759819 392 tGGTGLGLAIAAQLTAQLEGKLNLTNRSgGGLDVSITLPRR 432
Cdd:PRK11073 310 -GGTGLGLSIARNLIDQHSGKIEFTSWP-GHTEFSVYLPIR 348
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-430 |
2.99e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 48.44 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 328 LRRVMTNLLDNALKF-GEHAVIAIDNSSSEE-VVIHITDGGPGIPDDELEAVLQPFYRVETSRNrDTGGTGLGLAIAAQL 405
Cdd:cd16948 6 LSFIIGQIVSNALKYsKQGGKIEIYSETNEQgVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRN-FQESTGMGLYLVKKL 84
|
90 100
....*....|....*....|....*
gi 835759819 406 TAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16948 85 CDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
225-430 |
4.68e-07 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 52.24 E-value: 4.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 225 RAQILASISHDLQTPITRM-----KLRV--EMAGEPELRDKLLNDLDSMTRLVrEGIAYARssesleetplKLELNAW-- 295
Cdd:PRK10618 450 RKAFLQNIGDELKQPLQSLaqlaaQLRQtsDEEQQQPELDQLAEQSDVLVRLV-DNIQLLN----------MLETQDWkp 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 296 ---VNSIACDYQDIGKNVqfqagearLPIVTRP--------------------QALRRVMTNLLDNAL---KFGEHAV-I 348
Cdd:PRK10618 519 eqeLFSLQDLIDEVLPEV--------LPAIKRKglqllihnhlkaeqlrigdrDALRKILLLLLNYAItttAYGKITLeV 590
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 349 AIDNSSSEEVVIHITDGGPGIPDDELEAVLQPFYRvETSRNRDTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSIT 428
Cdd:PRK10618 591 DQDESSPDRLTIRILDTGAGVSIKELDNLHFPFLN-QTQGDRYGKASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIH 669
|
..
gi 835759819 429 LP 430
Cdd:PRK10618 670 LK 671
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
203-432 |
7.45e-07 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 50.00 E-value: 7.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 203 EVQRAAHAFNAMQARIQSY-LRERAQILASIsHD--LQTpITRMKLRVEMAGE--PELRDKLLNDLDSMTRLVREGIAYA 277
Cdd:COG4585 31 RAERAAELERELAARAEEArEEERRRIAREL-HDgvGQS-LSAIKLQLEAARRllDADPEAAREELEEIRELAREALAEL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 278 RS------SESLEETPLKLELNAWVNSIAcdyQDIGKNVQFQA--GEARLPIVTRpQALRRVMTNLLDNALKFGEHAVIA 349
Cdd:COG4585 109 RRlvrglrPPALDDLGLAAALEELAERLL---RAAGIRVELDVdgDPDRLPPEVE-LALYRIVQEALTNALKHAGATRVT 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 350 ID-NSSSEEVVIHITDGGPGIPDDEleavlqpfyrvetsrnrdTGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSIT 428
Cdd:COG4585 185 VTlEVDDGELTLTVRDDGVGFDPEA------------------APGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRAT 246
|
....
gi 835759819 429 LPRR 432
Cdd:COG4585 247 LPLA 250
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
317-430 |
1.72e-06 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 50.29 E-value: 1.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 317 ARLP-IVTRPQALRRVMTNLLDNALKfgehaVIAIDNSSSEE-----------VVIHITDGGPGIPDDELEAVLQPFYRV 384
Cdd:TIGR02938 376 ATLPaILGRELQLRSLFKALVDNAIE-----AMNIKGWKRRElsittalngdlIVVSILDSGPGIPQDLRYKVFEPFFTT 450
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 835759819 385 ETSRNRdtgGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:TIGR02938 451 KGGSRK---HIGMGLSVAQEIVADHGGIIDLDDDYSEGCRIIVEFR 493
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
358-430 |
1.95e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 46.60 E-value: 1.95e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 835759819 358 VVIHITDGGPGIPDDELEAVLQPFYRVetsrnRDTG-GTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:cd16919 48 VCLEVSDTGSGMPAEVLRRAFEPFFTT-----KEVGkGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
358-432 |
7.72e-06 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 48.14 E-value: 7.72e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835759819 358 VVIHITDGGPGIPDDELEAVLQPFYrveTSRNrdtGGTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLPRR 432
Cdd:PRK13837 608 VLLRVSDTGAGIDEAVLPHIFEPFF---TTRA---GGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDVYLPPS 676
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
327-430 |
1.36e-05 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 47.36 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 327 ALRRVMTNLLDnALKFGEHAVIAIDNSSSEE--------------VVIHITDGGPGIPDDELEAVLQPFYrvetsRNRDT 392
Cdd:PRK13557 281 ALLNVLINARD-AMPEGGRVTIRTRNVEIEDedlamyhglppgryVSIAVTDTGSGMPPEILARVMDPFF-----TTKEE 354
|
90 100 110
....*....|....*....|....*....|....*....
gi 835759819 393 G-GTGLGLAIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK13557 355 GkGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFP 393
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
224-278 |
6.35e-05 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 40.66 E-value: 6.35e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835759819 224 ERAQILASISHDLQTPITRMKLRVEMAGEP-------ELRDKLLNDLDSMTRLVREGIAYAR 278
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEkldeeqrEYLETILRSAERLLRLINDLLDLSR 62
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
224-278 |
1.05e-04 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 40.24 E-value: 1.05e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835759819 224 ERAQILASISHDLQTPITRMKLRVEMAGEPEL-------RDKLLNDLDSMTRLVREGIAYAR 278
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELseeqreyLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
222-278 |
2.81e-04 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 38.73 E-value: 2.81e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835759819 222 LRERAQILASISHDLQTPITRMKLRVEMAGEP--------ELRDKLLNDLDSMTRLVREGIAYAR 278
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEEllddeeqrEYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
331-430 |
5.02e-04 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 42.21 E-value: 5.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 331 VMTNLLDNALKfgehaviAIDNSSSEEVV-----------IHITDGGPGIPDDELEAVLQPFYRVETSrNRdtggtGLGL 399
Cdd:PRK11086 437 ILGNLIENALE-------AVGGEEGGEISvslhyrngwlhCEVSDDGPGIAPDEIDAIFDKGYSTKGS-NR-----GVGL 503
|
90 100 110
....*....|....*....|....*....|.
gi 835759819 400 AIAAQLTAQLEGKLNLTNRSGGGLDVSITLP 430
Cdd:PRK11086 504 YLVKQSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
338-430 |
1.52e-03 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 40.61 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 338 NALKfgeHA------VIAIDNSSsEEVVIHITDGGPGIpdDELEAVLQPFyrvetsrnrdtggtglGLAIAAQLTAQLEG 411
Cdd:PRK10935 482 NAIK---HAnaseiaVSCVTNPD-GEHTVSIRDDGIGI--GELKEPEGHY----------------GLNIMQERAERLGG 539
|
90
....*....|....*....
gi 835759819 412 KLNLTNRSGGGLDVSITLP 430
Cdd:PRK10935 540 TLTISQPPGGGTTVSLTFP 558
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
172-223 |
2.55e-03 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 35.69 E-value: 2.55e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 835759819 172 RQVVRPFSQFTRAVDSLDPAA-STPMTEKGPLEVQRAAHAFNAMQARIQSYLR 223
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDlTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
335-432 |
2.79e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 39.89 E-value: 2.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 335 LLDNALKFG----EHAVIAID-NSSSEEVVIHITDGGPGIPDDeleavlqpfyrVETSRnrdtgGTGLGLAIAAQLTAQL 409
Cdd:COG3920 407 LVTNALKHAflsgEGGRIRVSwRREDGRLRLTVSDNGVGLPED-----------VDPPA-----RKGLGLRLIRALVRQL 470
|
90 100
....*....|....*....|...
gi 835759819 410 EGKLNLtnRSGGGLDVSITLPRR 432
Cdd:COG3920 471 GGTLEL--DRPEGTRVRITFPLA 491
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
331-431 |
2.98e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 39.82 E-value: 2.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835759819 331 VMTNLLDNALKF------GEHAVIAIDNSSSEEVVIHITDGGPGIPDDELEAVlqpFYRVETSRNRDTGGTGLGLAIAAQ 404
Cdd:PRK15053 436 IVGNLLDNAFEAslrsdeGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKI---FEQGVSTRADEPGEHGIGLYLIAS 512
|
90 100
....*....|....*....|....*..
gi 835759819 405 LTAQLEGKLNLTNRSGGGLDVSITLPR 431
Cdd:PRK15053 513 YVTRCGGVITLEDNDPCGTLFSIFIPK 539
|
|
| HAMP |
pfam00672 |
HAMP domain; |
171-219 |
7.52e-03 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 34.52 E-value: 7.52e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 835759819 171 VRQVVRPFSQFTRAVDSLDPAA-STPMTEKGPLEVQRAAHAFNAMQARIQ 219
Cdd:pfam00672 3 ARRILRPLRRLAEAARRIASGDlDVRLPVSGRDEIGELARAFNQMAERLR 52
|
|
| |
