|
Name |
Accession |
Description |
Interval |
E-value |
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
13-859 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 1323.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 13 LDTLLFTSLESATAFCKLRGNPYVELVHWLHQLMQQQDGDLQQVIRHFALDEQQLTRDIVAALDVLPRGASSVSDLSEHI 92
Cdd:TIGR03345 1 LNPTSRRALEQAAALCVARGHPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLPRGNTRTPVFSPHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 93 DSAVERAWVFGSLKFGVSRIRGGHLLIGLLKTWNLANVLKSISAQFTRLNVEVLIEQFDAICANSKETQQAAAAADAPAG 172
Cdd:TIGR03345 81 VELLQEAWLLASLELGDGRIRSGHLLLALLTDPELRRLLGSISPELAKIDREALREALPALVEGSAEASAAAADAAPAGA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 173 AVPAAQGT-LAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPEP 251
Cdd:TIGR03345 161 AAGAAGTSaLDQYTTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 252 LQNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSATPIILFIDEIHTLIGAGGQQGTGDAANLLKPALARGQLRTI 331
Cdd:TIGR03345 241 LRNVRLLSLDLGLLQAGASVKGEFENRLKSVIDEVKASPQPIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 332 GATTWAEYKKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAV 411
Cdd:TIGR03345 321 AATTWAEYKKYFEKDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 412 ALLDTACARVAVSQSAPPAQLEDCLRHLAALDVEIEIAEREARVGAGDADRVTALLADRDAYEAKREALSRRWEEERSLV 491
Cdd:TIGR03345 401 SLLDTACARVALSQNATPAALEDLRRRIAALELELDALEREAALGADHDERLAELRAELAALEAELAALEARWQQEKELV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 492 KEIIRLRAALFAAGE---EDSAELRGQLAEQQQALNALQGDEPLLFAAVDENVVAAVVSDWTGIPLGRMVKNEIDAVLNL 568
Cdd:TIGR03345 481 EAILALRAELEADADapaDDDDALRAQLAELEAALASAQGEEPLVFPEVDAQAVAEVVADWTGIPVGRMVRDEIEAVLSL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 569 ADTLNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQEAHT 648
Cdd:TIGR03345 561 PDRLAERVIGQDHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAHT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 649 VSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSNVGT 728
Cdd:TIGR03345 641 VSRLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAGS 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 729 DLISAMCADPELMPEPDALSGALRQPLLEVFPPALLGRLLVVPYYPLSDEMLGQIVRLQLKRIQRRLEENHSIISEFDDS 808
Cdd:TIGR03345 721 DLIMALCADPETAPDPEALLEALRPELLKVFKPAFLGRMTVIPYLPLDDDVLAAIVRLKLDRIARRLKENHGAELVYSEA 800
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 835757664 809 VVEQIVQRCTEVESGGRMVDAILTNTLLPQMSQILLTASRSDEQYRRLHVT 859
Cdd:TIGR03345 801 LVEHIVARCTEVESGARNIDAILNQTLLPELSRQILERLAAGEPIERIHLD 851
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
10-865 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 1080.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 10 FGKLDTLLFTSLESATAFCKLRGNPYVELVHWLHQLMQQQDGDLQQVIRHFALDEQQLTRDIVAALDVLPR--GASSVSD 87
Cdd:COG0542 3 FEKFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLPKvsGSSGQPY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 88 LSEHIDSAVERAWVFgSLKFGVSRIRGGHLLIGLLKTWN--LANVLKSISaqftrLNVEVLIEQFDAICANSKETQQAAA 165
Cdd:COG0542 83 LSPRLKRVLELAELE-ARKLGDEYISTEHLLLALLREGEgvAARILKKLG-----ITLEALREALEELRGGSRVTSQNPE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 166 AAdapagavpaaQGTLAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIAD 245
Cdd:COG0542 157 SK----------TPALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVN 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 246 GDVPEPLQNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSATPIILFIDEIHTLIGAGGQQGTGDAANLLKPALAR 325
Cdd:COG0542 227 GDVPESLKDKRVLSLDLGALVAGAKYRGEFEERLKAVLDEVKKSEGNIILFIDELHTLVGAGGAEGAMDAANLLKPALAR 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 326 GQLRTIGATTWAEYKKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQ 405
Cdd:COG0542 307 GELRCIGATTLDEYRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLSDRYITDRF 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 406 LPDKAVALLDTACARVAVSQSAPPAQLEDCLRHLAALDVEIEIAEREARvgAGDADRVTALLADRDAYEAKREALSRRWE 485
Cdd:COG0542 387 LPDKAIDLIDEAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQD--EASFERLAELRDELAELEEELEALKARWE 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 486 EERSLVKEIIRLRAALFAAgEEDSAELRGQLAEQQQALNALqgdEPLLFAAVDENVVAAVVSDWTGIPLGRMVKNEIDAV 565
Cdd:COG0542 465 AEKELIEEIQELKEELEQR-YGKIPELEKELAELEEELAEL---APLLREEVTEEDIAEVVSRWTGIPVGKLLEGEREKL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 566 LNLADTLNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQE 645
Cdd:COG0542 541 LNLEEELHERVIGQDEAVEAVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDEDALIRIDMSEYME 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 646 AHTVSTLKGAPPgyvgygeggVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSN 725
Cdd:COG0542 621 KHSVSRLIGAPPgyvgyeeggQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTIIIMTSN 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 726 VGTDLISAMCADPelmPEPDALSGALRQPLLEVFPPALLGRLL-VVPYYPLSDEMLGQIVRLQLKRIQRRLEENHsIISE 804
Cdd:COG0542 701 IGSELILDLAEDE---PDYEEMKEAVMEELKKHFRPEFLNRIDeIIVFHPLSKEELRKIVDLQLKRLRKRLAERG-ITLE 776
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 835757664 805 FDDSVVEQIVQRCTEVESGGRMVDAILTNTLLPQMSQILLTASRSDEQyrRLHVTCEQGEF 865
Cdd:COG0542 777 LTDAAKDFLAEKGYDPEYGARPLKRAIQRELEDPLAEEILAGEIKEGD--TITVDVDDGEL 835
|
|
| chaperone_ClpB |
TIGR03346 |
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent ... |
21-815 |
0e+00 |
|
ATP-dependent chaperone ClpB; Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization]
Pssm-ID: 274529 [Multi-domain] Cd Length: 850 Bit Score: 677.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 21 LESATAFCKLRGNPYVELVHWLHQLMQQQDGDLQQVIRHFALDEQQLTRDIVAALDVLPR--GASSVSDLSEHIDSAVER 98
Cdd:TIGR03346 9 LQAAQSLALGRDHQQIEPEHLLKALLDQEGGLARPLLQKAGVNVGALRQALEKELERLPKvsGPGGQVYLSPDLNRLLNL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 99 AWVFGSlKFGVSRIRGGHLLIGLLKTWN-LANVLKSISAqfTRLNVEVLIEQF----DAICANSKETQQAaaaadapaga 173
Cdd:TIGR03346 89 AEKLAQ-KRGDEFISSEHLLLALLDDKGtLGKLLKEAGA--TADALEAAINAVrggqKVTDANAEDQYEA---------- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 174 vpaaqgtLAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPEPLQ 253
Cdd:TIGR03346 156 -------LEKYARDLTERAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPEGLK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 254 NIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSATPIILFIDEIHTLIGAGGQQGTGDAANLLKPALARGQLRTIGA 333
Cdd:TIGR03346 229 NKRLLALDMGALIAGAKYRGEFEERLKAVLNEVTKSEGQIILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 334 TTWAEYKKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAVAL 413
Cdd:TIGR03346 309 TTLDEYRKYIEKDAALERRFQPVFVDEPSVEDTISILRGLKERYEVHHGVRITDPAIVAAATLSHRYITDRFLPDKAIDL 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 414 LDTACARVAVSQSAPPAQLEDCLRHLAALDVEIEIAEREARVGAgdADRVTALLADRDAYEAKREALSRRWEEERSLV-- 491
Cdd:TIGR03346 389 IDEAAARIRMEIDSKPEELDELDRRIIQLEIEREALKKEKDEAS--KKRLEDLEKELADLEEEYAELEEQWKAEKASIqg 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 492 -----KEIIRLRAALFAA---------GE---EDSAELRGQLAEQQQALNalQGDEPLLFAAVDENVVAAVVSDWTGIPL 554
Cdd:TIGR03346 467 iqqikEEIEQVRLELEQAeregdlakaAElqyGKLPELEKQLQAAEQKLG--EEQNRLLREEVTAEEIAEVVSRWTGIPV 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 555 GRMVKNEIDAVLNLADTLNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQN 634
Cdd:TIGR03346 545 SKMLEGEREKLLHMEEELHERVVGQDEAVEAVSDAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELAKALAEFLFDSEDA 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 635 VITINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHID 714
Cdd:TIGR03346 625 MVRIDMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVD 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 715 FRNTIIILTSNVGTDLISAMC--ADPELMPEpdALSGALRQplleVFPPALLGRL-LVVPYYPLSDEMLGQIVRLQLKRI 791
Cdd:TIGR03346 705 FRNTVIIMTSNLGSDFIQELAggDDYEEMRE--AVMEVLRA----HFRPEFLNRIdEIVVFHPLGREQIARIVEIQLGRL 778
|
810 820
....*....|....*....|....
gi 835757664 792 QRRLEENHsIISEFDDSVVEQIVQ 815
Cdd:TIGR03346 779 RKRLAERK-ITLELSDAALDFLAE 801
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
106-798 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 554.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 106 KFGVSRIRGGHLLIGLLKTWN--LANVLKSISAQFTRLNVEVLIEQFDAICANSKETQQAAAAAdapagavpaaqgTLAQ 183
Cdd:CHL00095 97 DLGHNYIGTEHLLLALLEEGEgvAARVLENLGVDLSKIRSLILNLIGEIIEAILGAEQSRSKTP------------TLEE 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 184 YGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPEPLQNIQLWLLDIG 263
Cdd:CHL00095 165 FGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPDILEDKLVITLDIG 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 264 MLQAGAGMKGEFEARLQALINEVQSSATpIILFIDEIHTLIGAGGQQGTGDAANLLKPALARGQLRTIGATTWAEYKKYI 343
Cdd:CHL00095 245 LLLAGTKYRGEFEERLKRIFDEIQENNN-IILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHI 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 344 EKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAVALLDTACARVAV 423
Cdd:CHL00095 324 EKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKAIDLLDEAGSRVRL 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 424 SQSAPPAQLEDCLRHLAALDVEIEIAEREARvgagdadrvtalladrdaYEAKREALSRrweeerslvkeiirlraalfa 503
Cdd:CHL00095 404 INSRLPPAARELDKELREILKDKDEAIREQD------------------FETAKQLRDR--------------------- 444
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 504 ageedSAELRGQLAEQQQALNaLQGDEPLLFAAVDENVVAAVVSDWTGIPLGRMVKNEIDAVLNLADTLNQRVIGQRHGL 583
Cdd:CHL00095 445 -----EMEVRAQIAAIIQSKK-TEEEKRLEVPVVTEEDIAEIVSAWTGIPVNKLTKSESEKLLHMEETLHKRIIGQDEAV 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 584 DLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQEAHTVSTLKGAPPGYVGYG 663
Cdd:CHL00095 519 VAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKTELTKALASYFFGSEDAMIRLDMSEYMEKHTVSKLIGSPPGYVGYN 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 664 EGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSNVGTDLISAMCADPELMPE 743
Cdd:CHL00095 599 EGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQILDDGRLTDSKGRTIDFKNTLIIMTSNLGSKVIETNSGGLGFELS 678
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835757664 744 PDA--------LSGALRQPLLEVFPPALLGRL--LVVpYYPLSDEMLGQIVRLQLKRIQRRLEEN 798
Cdd:CHL00095 679 ENQlsekqykrLSNLVNEELKQFFRPEFLNRLdeIIV-FRQLTKNDVWEIAEIMLKNLFKRLNEQ 742
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
20-797 |
2.27e-175 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 529.03 E-value: 2.27e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 20 SLESATAFCKLRGNPYVELVHWLHQLMQQQDGDLQQVIRHFALDEQQLTRDIVAALDVLPR-----GASSVS-DLSEHID 93
Cdd:PRK10865 13 ALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVRPLLTSAGINAGQLRTDINQALSRLPQvegtgGDVQPSqDLVRVLN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 94 SAVERAWVFGSlKFGVSRIrggHLLIGLLKTWNLANVLKSISAqfTRLNVEVLIEQF---DAICANSKETQQAaaaadap 170
Cdd:PRK10865 93 LCDKLAQKRGD-NFISSEL---FVLAALESRGTLADILKAAGA--TTANITQAIEQMrggESVNDQGAEDQRQ------- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 171 agavpaaqgTLAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPE 250
Cdd:PRK10865 160 ---------ALKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPE 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 251 PLQNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSATPIILFIDEIHTLIGAGGQQGTGDAANLLKPALARGQLRT 330
Cdd:PRK10865 231 GLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHC 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 331 IGATTWAEYKKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKA 410
Cdd:PRK10865 311 VGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 411 VALLDTACARVAVSQSAPPAQLEDCLRHLAALDVEIEIAEREArvGAGDADRVTALLADRDAYEAKREALSRRWEEERSL 490
Cdd:PRK10865 391 IDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKES--DEASKKRLDMLNEELSDKERQYSELEEEWKAEKAS 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 491 VKEIIRLRAALFAAG-EEDSAELRGQLA--------------EQQQALNALQGDE-PLLFAAVDENVVAAVVSDWTGIPL 554
Cdd:PRK10865 469 LSGTQTIKAELEQAKiAIEQARRVGDLArmselqygkipeleKQLAAATQLEGKTmRLLRNKVTDAEIAEVLARWTGIPV 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 555 GRMVKNEIDAVLNLADTLNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQN 634
Cdd:PRK10865 549 SRMLESEREKLLRMEQELHHRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDA 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 635 VITINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHID 714
Cdd:PRK10865 629 MVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVD 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 715 FRNTIIILTSNVGTDLISAMCADPELmpepdalsGALRQPLLEV----FPPALLGRL-LVVPYYPLSDEMLGQIVRLQLK 789
Cdd:PRK10865 709 FRNTVVIMTSNLGSDLIQERFGELDY--------AHMKELVLGVvshnFRPEFINRIdEVVVFHPLGEQHIASIAQIQLQ 780
|
....*...
gi 835757664 790 RIQRRLEE 797
Cdd:PRK10865 781 RLYKRLEE 788
|
|
| ClpA |
TIGR02639 |
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, ... |
20-831 |
1.13e-165 |
|
ATP-dependent Clp protease ATP-binding subunit clpA; [Protein fate, Degradation of proteins, peptides, and glycopeptides]
Pssm-ID: 274241 [Multi-domain] Cd Length: 730 Bit Score: 499.55 E-value: 1.13e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 20 SLESATAFCKLRGNPYVELVHWLHQLMQqqDGDLQQVIRHFALD----EQQLTRDIVAALDVLPRGASSVSDLSEHIDSA 95
Cdd:TIGR02639 8 ILSDALEEAKERRHEFVTLEHLLLALLD--DNEAIEILEECGGDvellRKRLEDYLEENLPVIPEDIDEEPEQTVGVQRV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 96 VERAwVFGSLKFGVSRIRGGHLLIGLL---KTWNlANVLKSisAQFTRLNVEVLIEqfDAICANSKETQqaaaAADAPAG 172
Cdd:TIGR02639 86 IQRA-LLHVKSAGKKEIDIGDLLVALFdeeDSHA-SYFLKS--QGITRLDILNYIS--HGISKDDGKDQ----LGEEAGK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 173 AVPAAQGTLAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPEPL 252
Cdd:TIGR02639 156 EEEKGQDALEKYTVDLTEKAKNGKIDPLIGREDELERTIQVLCRRKKNNPLLVGEPGVGKTAIVEGLALRIAEGKVPERL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 253 QNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSATPIiLFIDEIHTLIGAG-GQQGTGDAANLLKPALARGQLRTI 331
Cdd:TIGR02639 236 KNAKIYSLDMGTLLAGTKYRGDFEERLKAVVSEIEKEPNAI-LFIDEIHTIVGAGaTSGGSMDASNLLKPALSSGKIRCI 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 332 GATTWAEYKKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAV 411
Cdd:TIGR02639 315 GSTTYEEYKNHFEKDRALSRRFQKIDVGEPSIEETVKILKGLKEQYEEFHHVKYSDEALEAAVELSARYINDRFLPDKAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 412 ALLDTACARVAVsqsappaqledclrhlaaldveieiaerearvgagdadrvtalladrdAYEAKREALSRrweeerslV 491
Cdd:TIGR02639 395 DVIDEAGAAFRL------------------------------------------------RPKAKKKANVN--------V 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 492 KEIirlraalfaageedsaelrgqlaeqqqalnalqgdepllfaavdENVVAAVvsdwTGIPLGRMVKNEIDAVLNLADT 571
Cdd:TIGR02639 419 KDI--------------------------------------------ENVVAKM----AKIPVKTVSSDDREQLKNLEKN 450
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 572 LNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLyggEQNVITINMSEFQEAHTVST 651
Cdd:TIGR02639 451 LKAKIFGQDEAIDQLVSAIKRSRAGLGDPNKPVGSFLFVGPTGVGKTELAKQLAEEL---GVHLLRFDMSEYMEKHTVSR 527
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 652 LKGAPPGYVGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSNVGTDLI 731
Cdd:TIGR02639 528 LIGSPPGYVGFEQGGLLTDAVRKHPHCVLLLDEIEKAHPDIYNILLQVMDYATLTDNNGRKADFRNVILIMTSNAGASEM 607
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 732 SAmcadPELMPEPDALSGALRQPLLEVFPPALLGRL-LVVPYYPLSDEMLGQIVRLQLKRIQRRLEENHsIISEFDDSVV 810
Cdd:TIGR02639 608 SK----PPIGFGGENRESKSLKAIKKLFSPEFRNRLdAIIHFNDLSEEMAEKIVKKFLDELQDQLNEKN-IELELTDDAK 682
|
810 820 830
....*....|....*....|....*....|....
gi 835757664 811 EQI-------------VQRCTEVESGGRMVDAIL 831
Cdd:TIGR02639 683 KYLaekgydeefgarpLARVIQEEIKKPLSDEIL 716
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
181-727 |
1.35e-112 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 361.85 E-value: 1.35e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 181 LAQYGQDLTARAREGKIDPVVGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPEPLQNIQLWLL 260
Cdd:PRK11034 169 MENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 261 DIGMLQAGAGMKGEFEARLQALINEVQSSATPiILFIDEIHTLIGAGGQQGTG-DAANLLKPALARGQLRTIGATTWAEY 339
Cdd:PRK11034 249 DIGSLLAGTKYRGDFEKRFKALLKQLEQDTNS-ILFIDEIHTIIGAGAASGGQvDAANLIKPLLSSGKIRVIGSTTYQEF 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 340 KKYIEKDPALTRRFQTVQVHEPDEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAVALLDTACA 419
Cdd:PRK11034 328 SNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGA 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 420 RvavSQSAPpaqledclrhlaaldveieIAEREARVGAGDADRVTALLADrdayeakrealsrrweeerslvkeiirlra 499
Cdd:PRK11034 408 R---ARLMP-------------------VSKRKKTVNVADIESVVARIAR------------------------------ 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 500 alfaageedsaelrgqlaeqqqalnalqgdepllfaavdenvvaavvsdwtgIPLGRMVKNEIDAVLNLADTLNQRVIGQ 579
Cdd:PRK11034 436 ----------------------------------------------------IPEKSVSQSDRDTLKNLGDRLKMLVFGQ 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 580 RHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLyggEQNVITINMSEFQEAHTVSTLKGAPPGY 659
Cdd:PRK11034 464 DKAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKAL---GIELLRFDMSEYMERHTVSRLIGAPPGY 540
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835757664 660 VGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSNVG 727
Cdd:PRK11034 541 VGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAG 608
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
565-726 |
2.18e-78 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 251.33 E-value: 2.18e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 565 VLNLADTLNQRVIGQRHGLDLIARRVKTSRAKLDDPNKPVGVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQ 644
Cdd:cd19499 2 LLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEYM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 645 EAHTVSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTS 724
Cdd:cd19499 82 EKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMTS 161
|
..
gi 835757664 725 NV 726
Cdd:cd19499 162 NH 163
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
602-767 |
1.80e-63 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 210.90 E-value: 1.80e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 602 KPVGVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRRPYSVVL 681
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 682 LDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHIDFRNTIIILTSNVGTDLISAMCADPElMPEPDALSGALRQPLLEVFPP 761
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRLGD-SPDYELLKEEVMDLLKKGFIP 159
|
....*.
gi 835757664 762 ALLGRL 767
Cdd:pfam07724 160 EFLGRL 165
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
362-452 |
6.87e-35 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 128.37 E-value: 6.87e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 362 DEAKAILMLRSTVSPLETHHQVLLLDEAVSAAVKLSHRYIPARQLPDKAVALLDTACARVAVSQSAPPAQLEDCLRHLAA 441
Cdd:pfam17871 1 SVEEAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAK 80
|
90
....*....|.
gi 835757664 442 LDVEIEIAERE 452
Cdd:pfam17871 81 LEIEKEALERE 91
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
582-725 |
6.92e-16 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 75.65 E-value: 6.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 582 GLDLIARRVKtsRAKLDDPNKPVgvfMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQEAHTVSTLKGAPpgyvg 661
Cdd:cd00009 2 GQEEAIEALR--EALELPPPKNL---LLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHF----- 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 835757664 662 ygEGGVLTEAVRRRPYSVVLLDEIEKAHPDVHEIFFQVfdkgwMEDGEGRHIDFRNTIIILTSN 725
Cdd:cd00009 72 --LVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRV-----LETLNDLRIDRENVRVIGATN 128
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
775-865 |
1.41e-15 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 72.48 E-value: 1.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 775 LSDEMLGQIVRLQLKRIQRRLEENHsIISEFDDSVVEQIVQRCTEVESGGRMVDAILTNTLLPQMSQILLTASRSDEQYR 854
Cdd:smart01086 1 LDKEDLVRIVDLPLNALQKRLAEKG-ITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAELILSGELKDGDTV 79
|
90
....*....|.
gi 835757664 855 RLHVTCEQGEF 865
Cdd:smart01086 80 VVDVDDGELVF 90
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
201-356 |
7.26e-14 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 69.87 E-value: 7.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 201 VGRDEEIRQMVDILMRRRQNNPLLTGEAGVGKTAVVEGLALRIADGDVPeplqniqLWLLDIGMLQAGAGMKGEFEARLQ 280
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP-------FLYLNASDLLEGLVVAELFGHFLV 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 835757664 281 ALINEVQSSATPIILFIDEIHTLIGAGGQQGTGDAANLLKPALARGQLRTIGATTwaeYKKYIEKDPALTRRFQTV 356
Cdd:cd00009 74 RLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRIDRENVRVIGATN---RPLLGDLDRALYDRLDIR 146
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
775-844 |
1.17e-13 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 67.05 E-value: 1.17e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 775 LSDEMLGQIVRLQLKRIQRRLEEnHSIISEFDDSVVEQIVQRCTEVESGGRMVDAILTNTLLPQMSQILL 844
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAE-RGITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLAEEIL 69
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
605-733 |
5.25e-13 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 67.40 E-value: 5.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 605 GVFMLCGPSGVGKTETALALAESLYGGEQNVITINMSEFQEAHTVS----TLKGAPPGYVGYGEGGVLTEAVRRRPYSVV 680
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQllliIVGGKKASGSGELRLRLALALARKLKPDVL 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 835757664 681 LLDEIEKAHPDVHEIFFQVFDKGWMEDGEGRHidfRNTIIILTSNVGTDLISA 733
Cdd:smart00382 83 ILDEITSLLDAEQEALLLLLEELRLLLLLKSE---KNLTVILTTNDEKDLGPA 132
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
223-354 |
4.53e-11 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 61.07 E-value: 4.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 223 LLTGEAGVGKTAVVEGLAlriadgdvpeplQNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSAtPIILFIDEIHT 302
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVA------------KELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLA-PCVIFIDEIDA 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 835757664 303 LIGAGGQQGTG---DAANLLKPALARGQLRT-----IGATTwaeykkYIEK-DPALTRRFQ 354
Cdd:pfam00004 69 LAGSRGSGGDSesrRVVNQLLTELDGFTSSNskvivIAATN------RPDKlDPALLGRFD 123
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
607-725 |
6.07e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 52.29 E-value: 6.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 607 FMLCGPSGVGKTETALALAESLYGgeQNVITINMSEFQeahTVSTLKGA--PPGYVGYGEGGVLTEAVRRRpySVVLLDE 684
Cdd:pfam07728 2 VLLVGPPGTGKTELAERLAAALSN--RPVFYVQLTRDT---TEEDLFGRrnIDPGGASWVDGPLVRAAREG--EIAVLDE 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 835757664 685 IEKAHPDVHEIFFQVFDKG--WMEDGEGR-HIDFRNTIIILTSN 725
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERrlLLPDGGELvKAAPDGFRLIATMN 118
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
198-401 |
4.77e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 51.81 E-value: 4.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 198 DPVVGRDEEIRQMVDILM-RRRQNNP-----------LLTGEAGVGKTAVVEGLA--LRIadgdvpePLQNIQLWLLdIG 263
Cdd:COG1223 2 DDVVGQEEAKKKLKLIIKeLRRRENLrkfglwpprkiLFYGPPGTGKTMLAEALAgeLKL-------PLLTVRLDSL-IG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 264 MLqagagmKGEFEARLQALINEVqsSATPIILFIDEIHTlIGA--GGQQGTGDAANLLKPALA-----RGQLRTIGATTW 336
Cdd:COG1223 74 SY------LGETARNLRKLFDFA--RRAPCVIFFDEFDA-IAKdrGDQNDVGEVKRVVNALLQeldglPSGSVVIAATNH 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 835757664 337 AEykkyiEKDPALTRRFQTV-QVHEPDEAKAILMLRSTVSPLETHHQvLLLDEAVSAAVKLSHRYI 401
Cdd:COG1223 145 PE-----LLDSALWRRFDEViEFPLPDKEERKEILELNLKKFPLPFE-LDLKKLAKKLEGLSGADI 204
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
583-733 |
5.13e-07 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 50.36 E-value: 5.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 583 LDLIARRVKTSRAKLDDPNKPVGVfMLCGPSGVGKTETALALAESLYGgeqNVITINMSEFQEAHTVSTLKgappgyvgy 662
Cdd:cd19481 6 REAVEAPRRGSRLRRYGLGLPKGI-LLYGPPGTGKTLLAKALAGELGL---PLIVVKLSSLLSKYVGESEK--------- 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 835757664 663 gEGGVLTEAVRRRPYSVVLLDEIEKA--------HPDVHEIFFQVFDKgWMEDGEGRhidfRNTIIILTSNVGTDLISA 733
Cdd:cd19481 73 -NLRKIFERARRLAPCILFIDEIDAIgrkrdssgESGELRRVLNQLLT-ELDGVNSR----SKVLVIAATNRPDLLDPA 145
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
52-447 |
1.15e-06 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 51.84 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 52 DLQQVIRHFALDEQQLTRDIVAALDVLPRGASSVSDLSEHIDSAVERAWVFGSLKFGVSRIRGGHLLIGLLKTWNLANVL 131
Cdd:COG0464 12 ALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAALLSALEL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 132 KSISAQFTRLNVEVLIEQFDAIcANSKETQQAAAAADAPAGAVPAAQGTLAQYGQDLTARAREGKIDPVVGRDE---EIR 208
Cdd:COG0464 92 LLLGELLLLLLLLLLLLLLLLD-LERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLGGLEEvkeELR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 209 QMVDIL-----MRRRQNNP-----LLTGEAGVGKTAVVEGLAlRIADGDVPEplqniqlwlLDIGMLqagAGMK-GEFEA 277
Cdd:COG0464 171 ELVALPlkrpeLREEYGLPpprglLLYGPPGTGKTLLARALA-GELGLPLIE---------VDLSDL---VSKYvGETEK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 278 RLQALINEVQSSAtPIILFIDEIHTLIGAGGQQGTGDAANLLkpalarGQLRT-----------IGATTWAEykkyiEKD 346
Cdd:COG0464 238 NLREVFDKARGLA-PCVLFIDEADALAGKRGEVGDGVGRRVV------NTLLTemeelrsdvvvIAATNRPD-----LLD 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 347 PALTRRFQ-TVQVHEPDEA--KAILMLRSTVSPLETHhqvLLLDEAVSAAVKLSHRYIparqlpdkaVALLDTAcARVAV 423
Cdd:COG0464 306 PALLRRFDeIIFFPLPDAEerLEIFRIHLRKRPLDED---VDLEELAEATEGLSGADI---------RNVVRRA-ALQAL 372
|
410 420
....*....|....*....|....
gi 835757664 424 SQSAPPAQLEDCLRHLAALDVEIE 447
Cdd:COG0464 373 RLGREPVTTEDLLEALEREDIFLK 396
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
218-363 |
6.22e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 46.98 E-value: 6.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 218 RQNNPLLTGEAGVGKTAVVEGLALRIADGDVPE-----PLQNIQLWLLDIGMLQAGAGMKGEFEARLQALINEVQSSAtP 292
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGViyidgEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLK-P 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 835757664 293 IILFIDEIHTLIGAGGQQG--TGDAANLLKPALARGQLRTIGATTWAEykkyIEKDPALTRRFQTVQVHEPDE 363
Cdd:smart00382 80 DVLILDEITSLLDAEQEALllLLEELRLLLLLKSEKNLTVILTTNDEK----DLGPALLRRRFDRRIVLLLIL 148
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
608-775 |
2.51e-05 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 44.51 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 608 MLCGPSGVGKTETALALAESLYGgeqNVITINMSEFqeahtVSTLKGAPPgyvgYGEGGVLTEAVRRRPySVVLLDEIEK 687
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKELGA---PFIEISGSEL-----VSKYVGESE----KRLRELFEAAKKLAP-CVIFIDEIDA 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 688 AHPDVHEIFFQVFDKG------WMEDGEgrhIDFRNTIIILTSNvgtdlisamcadpelmpEPDALsgalrqpllevfPP 761
Cdd:pfam00004 69 LAGSRGSGGDSESRRVvnqlltELDGFT---SSNSKVIVIAATN-----------------RPDKL------------DP 116
|
170
....*....|....
gi 835757664 762 ALLGRLLVVPYYPL 775
Cdd:pfam00004 117 ALLGRFDRIIEFPL 130
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
205-356 |
4.87e-05 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 44.58 E-value: 4.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 205 EEIRQMVDILMRRRQNNP---------LLTGEAGVGKTAVVEGLALRIadgdvpeplqNIQLWLLDIGMLQAGAgmKGEF 275
Cdd:cd19481 3 ASLREAVEAPRRGSRLRRyglglpkgiLLYGPPGTGKTLLAKALAGEL----------GLPLIVVKLSSLLSKY--VGES 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 276 EARLQALINEVQSSAtPIILFIDEIHTLIGAGGQQGTGDAANLLKPAL--------ARGQLRTIGATTWAEykkyiEKDP 347
Cdd:cd19481 71 EKNLRKIFERARRLA-PCILFIDEIDAIGRKRDSSGESGELRRVLNQLlteldgvnSRSKVLVIAATNRPD-----LLDP 144
|
170
....*....|.
gi 835757664 348 ALTR--RFQTV 356
Cdd:cd19481 145 ALLRpgRFDEV 155
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
199-248 |
8.18e-05 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 44.03 E-value: 8.18e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 835757664 199 PVVGRDEEIRQMVDILMRRRQNNP---LLTGEAGVGKTAVVEGLALRIADGDV 248
Cdd:pfam13191 1 RLVGREEELEQLLDALDRVRSGRPpsvLLTGEAGTGKTTLLRELLRALERDGG 53
|
|
| CDC48 |
TIGR01243 |
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ... |
205-403 |
2.06e-04 |
|
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.
Pssm-ID: 273521 [Multi-domain] Cd Length: 733 Bit Score: 44.90 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 205 EEIRQMVDILMRRRQ----------NNPLLTGEAGVGKTAVVEGLAlriadgdvpeplQNIQLWLLDIGMLQAGAGMKGE 274
Cdd:TIGR01243 188 EKIREMVELPMKHPElfehlgieppKGVLLYGPPGTGKTLLAKAVA------------NEAGAYFISINGPEIMSKYYGE 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 275 FEARLQALINEVQSSAtPIILFIDEIHTlIGAGGQQGTGDAANLLKPAL--------ARGQLRTIGATTWAEykkyiEKD 346
Cdd:TIGR01243 256 SEERLREIFKEAEENA-PSIIFIDEIDA-IAPKREEVTGEVEKRVVAQLltlmdglkGRGRVIVIGATNRPD-----ALD 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835757664 347 PALTR--RFQ---TVQVHEPDEAKAILMlrstvspLETHHQVLLLDEAVSAAVKLSHRYIPA 403
Cdd:TIGR01243 329 PALRRpgRFDreiVIRVPDKRARKEILK-------VHTRNMPLAEDVDLDKLAEVTHGFVGA 383
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
436-643 |
2.34e-04 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 44.52 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 436 LRHLAALDVEIEIAEREARVGAGDADRVTALLADRDAYEAKREALSRRWEEERSLVKEIIRLRAALFAAGEEDSAELRGQ 515
Cdd:COG0464 38 LLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAALLSALELLLLGELLLLLLLLLLLLLLLLDLERA 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 516 LAEQQQALNALQGDEPLLFAAVDENVVAAVVSDWTGIPLGRMVKNEidavlNLADTLNQRVIGQRHGLDLIARRVKtsra 595
Cdd:COG0464 118 LLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLGGLE-----EVKEELRELVALPLKRPELREEYGL---- 188
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 835757664 596 klddpnKPVGVFMLCGPSGVGKTETALALAESLyGGeqNVITINMSEF 643
Cdd:COG0464 189 ------PPPRGLLLYGPPGTGKTLLARALAGEL-GL--PLIEVDLSDL 227
|
|
| McrB |
COG1401 |
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ... |
408-691 |
3.24e-04 |
|
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];
Pssm-ID: 441011 [Multi-domain] Cd Length: 477 Bit Score: 44.38 E-value: 3.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 408 DKAVALLDTACARVAVSQSAPPAQLEDCLRHLAALDVEIEIAEREARVGAGDADRVTALLADRDAYEAKREALSRRWEEE 487
Cdd:COG1401 35 DLRGAAELATRLAERLSEELLRADRAARATELVEELSAALEVVVLLLDLEKVELNEKLALSEAAVAIEELYELEADSEIE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 488 RSLVKEIIRLRAALFAAGEEDSAELRGQLAEQQQALNAlQGDEPLLFAAVDENVVAAVVSDWTGIPLGRMVKNEIDAVLN 567
Cdd:COG1401 115 AVGLLLELAERSDALEALERARLLLELADLEERAALET-EVLEALEAELEELLAAPEDLSADALAAELSAAEELYSEDLE 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 568 LADTLNQRVIGQRHGlDLIARRVKTSRAKlddPNKpvgvfMLCGPSGVGKTETALALAESLYGGEQNVITI-----NMS- 641
Cdd:COG1401 194 SEDDYLKDLLREKFE-ETLEAFLAALKTK---KNV-----ILAGPPGTGKTYLARRLAEALGGEDNGRIEFvqfhpSWSy 264
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 835757664 642 -EFQEAHTVSTLKGappgyVGYGEGGVLTEAVRR------RPYsVVLLDEIEKAHPD 691
Cdd:COG1401 265 eDFLLGYRPSLDEG-----KYEPTPGIFLRFCLKaeknpdKPY-VLIIDEINRANVE 315
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
590-643 |
1.05e-03 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 42.28 E-value: 1.05e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 835757664 590 VKTSRAKLDDPNKPVGVFMlcGPSGVGKTETALALAESLYG--GEQNVITINMSEF 643
Cdd:PRK12402 24 VERLSRAVDSPNLPHLLVQ--GPPGSGKTAAVRALARELYGdpWENNFTEFNVADF 77
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
430-530 |
1.55e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 430 AQLEDCLRHLAALDVEIEIAEREARVGAGDADRVTALLAD-RDAYEAKREALSRRWEEERSLVKEIIRLRAALfAAGEED 508
Cdd:COG1196 232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEElRLELEELELELEEAQAEEYELLAELARLEQDI-ARLEER 310
|
90 100
....*....|....*....|..
gi 835757664 509 SAELRGQLAEQQQALNALQGDE 530
Cdd:COG1196 311 RRELEERLEELEEELAELEEEL 332
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
439-529 |
1.89e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 439 LAALDVEIEIAEREARVGagdADRVTALLADRDAYEAKREALSR----RWEEE--RSLVKEIIRLRAALFA--AGEEDSA 510
Cdd:COG4913 612 LAALEAELAELEEELAEA---EERLEALEAELDALQERREALQRlaeySWDEIdvASAEREIAELEAELERldASSDDLA 688
|
90
....*....|....*....
gi 835757664 511 ELRGQLAEQQQALNALQGD 529
Cdd:COG4913 689 ALEEQLEELEAELEELEEE 707
|
|
| TIGR02928 |
TIGR02928 |
orc1/cdc6 family replication initiation protein; Members of this protein family are found ... |
198-532 |
2.08e-03 |
|
orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274354 [Multi-domain] Cd Length: 365 Bit Score: 41.46 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 198 DPVVGRDEEIRQMVDIL---MR-RRQNNPLLTGEAGVGKTAVVEGL--ALRIADGDVPEPLQNIQL--------WLLDIG 263
Cdd:TIGR02928 15 DRIVHRDEQIEELAKALrpiLRgSRPSNVFIYGKTGTGKTAVTKYVmkELEEAAEDRDVRVVTVYVncqildtlYQVLVE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 264 MLQAGAGMKGEFEAR-------LQALINEVQSSATPIILFIDEIHTLIGAGGQ--------QGTGDAANllkpalarGQL 328
Cdd:TIGR02928 95 LANQLRGSGEEVPTTglstsevFRRLYKELNERGDSLIIVLDEIDYLVGDDDDllyqlsraRSNGDLDN--------AKV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 329 RTIGATTWAEYKKYIekDPALTRRFQTVQVHEP----DEAKAILMLRSTVSplethhqvlLLDEAVSAAVklshryIP-- 402
Cdd:TIGR02928 167 GVIGISNDLKFRENL--DPRVKSSLCEEEIIFPpydaEELRDILENRAEKA---------FYDGVLDDGV------IPlc 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 403 ArqlpdkAVALLDTACARVAVsqsappaqleDCLRHlaaldvEIEIAEREarvgagDADRVTallaDRDAYEAKREAlsr 482
Cdd:TIGR02928 230 A------ALAAQEHGDARKAI----------DLLRV------AGEIAERE------GAERVT----EDHVEKAQEKI--- 274
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 835757664 483 rweeERSLVKEIIR---------LRAALFAAGEEDSAELRGQLAEQQQALNALQGDEPL 532
Cdd:TIGR02928 275 ----EKDRLLELIRglpthsklvLLAIANLAANDEDPFRTGEVYEVYKEVCEDIGVDPL 329
|
|
| Clp_N |
pfam02861 |
Clp amino terminal domain, pathogenicity island component; This short domain is found in one ... |
24-76 |
2.27e-03 |
|
Clp amino terminal domain, pathogenicity island component; This short domain is found in one or two copies at the amino terminus of ClpA and ClpB proteins from bacteria and eukaryotes. The function of these domains is uncertain but they may form a protein binding site. In many bacterial species, including E.coli, this region represents the N-terminus of one of the key components of the pathogenicity island complex that injects toxin from one bacterium into another.
Pssm-ID: 460724 [Multi-domain] Cd Length: 53 Bit Score: 36.73 E-value: 2.27e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 835757664 24 ATAFCKLRGNPYVELVHWLHQLMQQQDGDLQQVIRHFALDEQQLTRDIVAALD 76
Cdd:pfam02861 1 AQELARALGHQYIGTEHLLLALLEEDDGLAARLLKKAGVDLDALREAIEKLLG 53
|
|
| RecA-like_Ycf46-like |
cd19507 |
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ... |
223-315 |
3.38e-03 |
|
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410915 [Multi-domain] Cd Length: 161 Bit Score: 39.27 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835757664 223 LLTGEAGVGKTAVVEGLALRIadgdvpeplqNIQLWLLDIGMLQAGagMKGEFEARLQALINEVQSSAtPIILFIDEIHT 302
Cdd:cd19507 35 LLVGIQGTGKSLTAKAIAGVW----------QLPLLRLDMGRLFGG--LVGESESRLRQMIQTAEAIA-PCVLWIDEIEK 101
|
90
....*....|...
gi 835757664 303 liGAGGQQGTGDA 315
Cdd:cd19507 102 --GFSNADSKGDS 112
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
223-300 |
5.18e-03 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 38.54 E-value: 5.18e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835757664 223 LLTGEAGVGKTAVVEGLAlriADGDVPeplqniqlwLLDIGMLQAGAGMKGEFEARLQALINEVQSSAtPIILFIDEI 300
Cdd:cd19518 38 LLHGPPGCGKTMLANAIA---GELKVP---------FLKISATEIVSGVSGESEEKIRELFDQAISNA-PCIVFIDEI 102
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
200-236 |
5.50e-03 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 40.22 E-value: 5.50e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 835757664 200 VVGRDEEIRQMVDIL----MRRRQNNPLLTGEAGVGKTAVV 236
Cdd:COG1474 28 LPHREEEIEELASALrpalRGERPSNVLIYGPTGTGKTAVA 68
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
576-641 |
8.05e-03 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 39.47 E-value: 8.05e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835757664 576 VIGQRHgldlIARRVKTSRAKLDDPNkpvgvFMLCGPSGVGKTETALALAESLYGG--EQNVITINMS 641
Cdd:PRK00440 19 IVGQEE----IVERLKSYVKEKNMPH-----LLFAGPPGTGKTTAALALARELYGEdwRENFLELNAS 77
|
|
| |
