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Conserved domains on  [gi|823306005|ref|WP_047060936|]
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MULTISPECIES: ABC transporter permease [Enterobacter]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
16-275 3.18e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 256.19  E-value: 3.18e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  16 AWQGVEWQPGLWLAWGVIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALA 95
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  96 AVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRI 175
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 176 RHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWW 255
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247
                        250       260
                 ....*....|....*....|
gi 823306005 256 LTTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLG 267
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
16-275 3.18e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 256.19  E-value: 3.18e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  16 AWQGVEWQPGLWLAWGVIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALA 95
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  96 AVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRI 175
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 176 RHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWW 255
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247
                        250       260
                 ....*....|....*....|
gi 823306005 256 LTTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLG 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
32-272 9.42e-52

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 169.87  E-value: 9.42e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005   32 VIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIA 111
Cdd:TIGR02790   7 IIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  112 GAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGTF 191
Cdd:TIGR02790  87 GYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  192 FAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVLAT 271
Cdd:TIGR02790 167 WQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAF 246

                  .
gi 823306005  272 N 272
Cdd:TIGR02790 247 N 247
nikC PRK10417
nickel transporter permease NikC; Provisional
23-274 4.44e-50

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 166.00  E-value: 4.44e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  23 QPGLWLAWGVIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLV 102
Cdd:PRK10417   3 RWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 103 VGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVE 182
Cdd:PRK10417  83 LGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 183 AAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGV 262
Cdd:PRK10417 163 AARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGL 242
                        250
                 ....*....|..
gi 823306005 263 VVIAVVLATNRI 274
Cdd:PRK10417 243 ALFISVMAFNLL 254
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
88-268 2.63e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.14  E-value: 2.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  88 HSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVD--------VLLSIPSLLLSLTVIILLGFGTVNAAIAVGVA 159
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDlllslpslVLGLLLVLLFGVLLGWGILPGLGLPALILALL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 160 SIASFARLARGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGtPPPVPEW 239
Cdd:cd06261   83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGT 161
                        170       180
                 ....*....|....*....|....*....
gi 823306005 240 GLLIAEGRNYLSTAWWLTTFPGVVVIAVV 268
Cdd:cd06261  162 GLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
104-274 7.58e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 7.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  104 GTGLGVIAGAFAGR-VESLLMRFVDVLL---SIPSLLLSLTVIILLGFG-TVNAAIAVGVASIASFARLARGEVVRIRHT 178
Cdd:pfam00528   1 GIPLGIIAALRRGRrLDRLLRPLIDLLQalpSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  179 DYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLgyGTPPPVPEWGLLIAEGRNYlSTAWWLTT 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDY-PEIQGPVL 157
                         170
                  ....*....|....*.
gi 823306005  259 FPGVVVIAVVLATNRI 274
Cdd:pfam00528 158 AAALILLLLNLLVDIL 173
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
16-275 3.18e-85

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 256.19  E-value: 3.18e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  16 AWQGVEWQPGLWLAWGVIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALA 95
Cdd:COG1173    8 AWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  96 AVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRI 175
Cdd:COG1173   88 AVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSL 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 176 RHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWW 255
Cdd:COG1173  168 REREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLTAPW 247
                        250       260
                 ....*....|....*....|
gi 823306005 256 LTTFPGVVVIAVVLATNRIS 275
Cdd:COG1173  248 LALFPGLAIVLTVLAFNLLG 267
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
32-272 9.42e-52

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 169.87  E-value: 9.42e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005   32 VIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIA 111
Cdd:TIGR02790   7 IIAVLFLLAIFAPWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTIGLLIGGLA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  112 GAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGTF 191
Cdd:TIGR02790  87 GYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFVLAARTSGASH 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  192 FAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVLAT 271
Cdd:TIGR02790 167 WQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLMIYPGLAILISVMAF 246

                  .
gi 823306005  272 N 272
Cdd:TIGR02790 247 N 247
nikC PRK10417
nickel transporter permease NikC; Provisional
23-274 4.44e-50

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 166.00  E-value: 4.44e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  23 QPGLWLAWGVIILAAFAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLV 102
Cdd:PRK10417   3 RWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 103 VGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVE 182
Cdd:PRK10417  83 LGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 183 AAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGV 262
Cdd:PRK10417 163 AARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGL 242
                        250
                 ....*....|..
gi 823306005 263 VVIAVVLATNRI 274
Cdd:PRK10417 243 ALFISVMAFNLL 254
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
32-272 3.66e-47

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 159.51  E-value: 3.66e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  32 VIILAAFAAVAPgLLTHYSPiEGIAGAQRL--APQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGV 109
Cdd:PRK15082  45 VLLLIVVAIFAP-WIAPYDA-ENYFDYDALnaGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGL 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 110 IAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGG 189
Cdd:PRK15082 123 LAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGA 202
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 190 TFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVL 269
Cdd:PRK15082 203 SDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVALFPSLAIFLTVL 282

                 ...
gi 823306005 270 ATN 272
Cdd:PRK15082 283 AFN 285
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
7-272 9.82e-47

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 158.44  E-value: 9.82e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005   7 AAAARKRVPAWQGVEWQPGLWLAWGVIILAA-FAAVAPGLLTHYSPIEGIAGAQRLAPQAGHWLGTDQLGRDVYTRIVYG 85
Cdd:PRK09881  13 QKQTRFNGAKLVWMLKGSPLTVTGAVIIVLMlLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  86 ASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFA 165
Cdd:PRK09881  93 SQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYV 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 166 RLARGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAE 245
Cdd:PRK09881 173 RLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVAN 252
                        250       260
                 ....*....|....*....|....*..
gi 823306005 246 GRNYLSTAWWLTTFPGVVVIAVVLATN 272
Cdd:PRK09881 253 GRNYVLDQWWYCAFPGAAILLTAVGFN 279
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
32-272 1.20e-42

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 147.62  E-value: 1.20e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  32 VIILAAFAAVAPGLLTHYSPIEGIAGAQRLAP---QAGHW---LGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGT 105
Cdd:PRK10913  38 YVVIMLFIAIFANWIAPHNPAEQFRDALLAPPvwqEGGSWahiLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGV 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 106 GLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAF 185
Cdd:PRK10913 118 ILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASR 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 186 GSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVI 265
Cdd:PRK10913 198 VAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAIL 277

                 ....*..
gi 823306005 266 AVVLATN 272
Cdd:PRK10913 278 LTVLAFN 284
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
30-272 1.17e-39

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 139.95  E-value: 1.17e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  30 WGVIILAAFAAVAPgLLTHYSPIEGIAGAQRLAP------QAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVV 103
Cdd:COG4171   34 YGFLFLILLALFGP-LLAPYSPDQQFIGALLLPPswddngDVSFFLGTDDLGRDILSRLLYGARYTFGSALLVVLAAAII 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 104 GTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEA 183
Cdd:COG4171  113 GGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQFIHAIYQAVHQELKKEYVLA 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 184 AFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVV 263
Cdd:COG4171  193 ARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLGDSLELIYLAPWTVILPGLA 272

                 ....*....
gi 823306005 264 VIAVVLATN 272
Cdd:COG4171  273 IMFSVLIVN 281
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
62-269 9.03e-38

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 136.05  E-value: 9.03e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  62 APQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLsltV 141
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYL---L 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 142 IILLGFGTVNAAIAVGVASIASFARLA---RGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQA 218
Cdd:COG4239  193 IILSSIFQPSFWLLLGILLLFGWMGLVgvvRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMVATLTFLPFILSGA 272
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 823306005 219 ILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLsTAWWLtTFPGVVVIAVVL 269
Cdd:COG4239  273 ITTLTSLDFLGFGLPPGSPSLGELLAQGKNNL-QAPWL-GLSAFVVLALML 321
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
32-274 8.61e-33

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 121.87  E-value: 8.61e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  32 VIILAAFAAVAPgLLTHYSPIEGIAGAQRLAP--QAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGV 109
Cdd:PRK15406  46 LVLIALFVILAP-MLSQFAYDDTDWGMMSSAPdmESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGS 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 110 IAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGG 189
Cdd:PRK15406 125 LSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGV 204
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 190 TFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVVVIAVVL 269
Cdd:PRK15406 205 STRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLF 284

                 ....*
gi 823306005 270 ATNRI 274
Cdd:PRK15406 285 CFNFI 289
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
62-269 3.23e-24

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 99.67  E-value: 3.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  62 APQAGHWLGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLsltV 141
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFL---I 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 142 IILLGFGTVNAAIAVGVASI---ASFARLARGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQA 218
Cdd:PRK15021 193 ILLSSVVQPNFWWLLAITVLfgwMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSS 272
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 823306005 219 ILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWW-LTTFPGVVVIAVVL 269
Cdd:PRK15021 273 ITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLgITAFLSVAILLSLL 324
PRK15111 PRK15111
peptide ABC transporter permease SapC;
30-272 3.51e-18

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 82.44  E-value: 3.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  30 WGVIILAAFAAVApGLLTHYSPIEGIAGAQRLAPQAGHW------LGTDQLGRDVYTRIVYGASHSLSAALAAVTMGLVV 103
Cdd:PRK15111  34 YGCAGLALLCLFG-GWLAPYGIDQQFLGYQLLPPSWSRYgevsffLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLC 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 104 GTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLARGEVVRIRHTDYVEA 183
Cdd:PRK15111 113 GLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMFAVWLALLPRMVRSIYSAVHDELEKEYVIA 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 184 AFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGTPPPVPEWGLLIAEGRNYLSTAWWLTTFPGVV 263
Cdd:PRK15111 193 ARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDSLELIYVAPWTVMLPGAA 272

                 ....*....
gi 823306005 264 VIAVVLATN 272
Cdd:PRK15111 273 IMLSVLLVN 281
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
88-268 2.63e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.14  E-value: 2.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  88 HSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVD--------VLLSIPSLLLSLTVIILLGFGTVNAAIAVGVA 159
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDlllslpslVLGLLLVLLFGVLLGWGILPGLGLPALILALL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 160 SIASFARLARGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYGtPPPVPEW 239
Cdd:cd06261   83 LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPGT 161
                        170       180
                 ....*....|....*....|....*....
gi 823306005 240 GLLIAEGRNYLSTAWWLTTFPGVVVIAVV 268
Cdd:cd06261  162 GLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
104-274 7.58e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 7.58e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  104 GTGLGVIAGAFAGR-VESLLMRFVDVLL---SIPSLLLSLTVIILLGFG-TVNAAIAVGVASIASFARLARGEVVRIRHT 178
Cdd:pfam00528   1 GIPLGIIAALRRGRrLDRLLRPLIDLLQalpSFVLAILLVVIAILSILGhGILPAIILALLGWAGYARLIRRAALRSLPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  179 DYVEAAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLgyGTPPPVPEWGLLIAEGRNYlSTAWWLTT 258
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDY-PEIQGPVL 157
                         170
                  ....*....|....*.
gi 823306005  259 FPGVVVIAVVLATNRI 274
Cdd:pfam00528 158 AAALILLLLNLLVDIL 173
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
73-219 1.15e-08

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 55.07  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  73 QLGRDVYTRIVYGASHSLSAALAAVTMGLVVGTGLGVIAGAFAGRVESLLMRFVDVLLSIPSLLLSLTVIILL------- 145
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLfavklgw 161
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005 146 ----GFGTVNA------------AIAVGVASIASFARLARGEVVRIRHTDYVEAAFGSGGTFFAVLWRHILPNALTAVLA 209
Cdd:COG0601  162 lpvsGRVSPWEdfldalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241
                        170
                 ....*....|
gi 823306005 210 FATLQFGQAI 219
Cdd:COG0601  242 VLGLQLGGLL 251
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
26-231 9.76e-04

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 39.83  E-value: 9.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005   26 LWLAWGVIILAAFAAVApGLLTHYSPIEGIAGAQRLAPQAGHWLGTDqlgRDVYTRIVYGASHSLSAALAAVTMGLVVGT 105
Cdd:TIGR01097   4 LIRIWLLALLVALYVWA-FALLGFDLARLLAGPGQMADLLGRMFPPD---WSYLPRILKALLETLAMAILGTVLAAVLAV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 823306005  106 GLGVIA--GAFAGRVESLLMRFV-DVLLSIPSLLLSLTVIILLGFGTVNAAIAVGVASIASFARLArGEVVRIRHTDYVE 182
Cdd:TIGR01097  80 PLALLAarNITPSPWLYGLARLLlNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLF-AEAIEEVDPGPVE 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 823306005  183 AAFGSGGTFFAVLWRHILPNALTAVLAFATLQFGQAILALSTLSFLGYG 231
Cdd:TIGR01097 159 ALRATGASKLQVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAG 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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