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Conserved domains on  [gi|808046148|ref|WP_046208129|]
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MULTISPECIES: class I SAM-dependent methyltransferase [Staphylococcus]

Protein Classification

class I SAM-dependent DNA methyltransferase( domain architecture ID 11471966)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:1904047
PubMed:  23180741|12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
4-138 9.69e-33

Predicted methyltransferase, contains TPR repeat [General function prediction only];


:

Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 117.02  E-value: 9.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   4 YEEMSYYYDQ-LTLDQPYESWLDIVE-----FYAKNKSTILDIGCGTGSFTSKLND-FDCITGMDLSVDMLSIAMQKSSE 76
Cdd:COG4976   11 FDQYADSYDAaLVEDLGYEAPALLAEellarLPPGPFGRVLDLGCGTGLLGEALRPrGYRLTGVDLSEEMLAKAREKGVY 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 808046148  77 VNWIEGDMTDFD-LNQQFDVItIFCDSLNYLteyEDVLSTFQQVYHHLEPNeGIFMFDVHTEH 138
Cdd:COG4976   91 DRLLVADLADLAePDGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPG-GLFIFSVEDAD 148
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
4-138 9.69e-33

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 117.02  E-value: 9.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   4 YEEMSYYYDQ-LTLDQPYESWLDIVE-----FYAKNKSTILDIGCGTGSFTSKLND-FDCITGMDLSVDMLSIAMQKSSE 76
Cdd:COG4976   11 FDQYADSYDAaLVEDLGYEAPALLAEellarLPPGPFGRVLDLGCGTGLLGEALRPrGYRLTGVDLSEEMLAKAREKGVY 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 808046148  77 VNWIEGDMTDFD-LNQQFDVItIFCDSLNYLteyEDVLSTFQQVYHHLEPNeGIFMFDVHTEH 138
Cdd:COG4976   91 DRLLVADLADLAePDGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPG-GLFIFSVEDAD 148
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 37-126 5.39e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 76.06  E-value: 5.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   37 ILDIGCGTGSFTSKL-NDFDC-ITGMDLSVDMLSIAMQKSSE----VNWIEGDMTDFDL-NQQFDVITIFCdSLNYLTEy 109
Cdd:pfam13649   1 VLDLGCGTGRLTLALaRRGGArVTGVDLSPEMLERARERAAEaglnVEFVQGDAEDLPFpDGSFDLVVSSG-VLHHLPD- 78

                          90
                  ....*....|....*..
gi 808046148  110 EDVLSTFQQVYHHLEPN 126
Cdd:pfam13649  79 PDLEAALREIARVLKPG 95
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 36-134 1.85e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 56.28  E-value: 1.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  36 TILDIGCGTGSFTSKLNDFDC--ITGMDLSVDMLSIAMQ-----KSSEVNWIEGDMTDFDL--NQQFDVItIFCDSLNYL 106
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGarVTGVDISPVALELARKaaaalLADNVEVLKGDAEELPPeaDESFDVI-ISDPPLHHL 79

                         90       100
                 ....*....|....*....|....*...
gi 808046148 107 teYEDVLSTFQQVYHHLEPNeGIFMFDV 134
Cdd:cd02440   80 --VEDLARFLEEARRLLKPG-GVLVLTL 104
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 26-132 7.16e-10

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 57.30  E-value: 7.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   26 IVEFYAKNKSTILDIGCGTGSFTSKL---NDFDCITGMDLSVDMLSIAMQKSSE-VNWIEGDMTDFDL-NQQFDVITI-- 98
Cdd:TIGR02072  27 LKEKGIFIPASVLDIGCGTGYLTRALlkrFPQAEFIALDISAGMLAQAKTKLSEnVQFICGDAEKLPLeDSSFDLIVSnl 106

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 808046148   99 ---FCDSLNylteyedvlSTFQQVYHHLEPNeGIFMF 132
Cdd:TIGR02072 107 alqWCDDLS---------QALSELARVLKPG-GLLAF 133
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 31-98 6.49e-09

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 54.39  E-value: 6.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  31 AKNKSTILDIGCGTG----SFTSKLNDFDCITGMDLSVDMLSIAMQK------SSEVNWIEGDMTD--FDlNQQFDVITI 98
Cdd:PRK00216  49 VRPGDKVLDLACGTGdlaiALAKAVGKTGEVVGLDFSEGMLAVGREKlrdlglSGNVEFVQGDAEAlpFP-DNSFDAVTI 127
 
Name Accession Description Interval E-value
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
4-138 9.69e-33

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 117.02  E-value: 9.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   4 YEEMSYYYDQ-LTLDQPYESWLDIVE-----FYAKNKSTILDIGCGTGSFTSKLND-FDCITGMDLSVDMLSIAMQKSSE 76
Cdd:COG4976   11 FDQYADSYDAaLVEDLGYEAPALLAEellarLPPGPFGRVLDLGCGTGLLGEALRPrGYRLTGVDLSEEMLAKAREKGVY 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 808046148  77 VNWIEGDMTDFD-LNQQFDVItIFCDSLNYLteyEDVLSTFQQVYHHLEPNeGIFMFDVHTEH 138
Cdd:COG4976   91 DRLLVADLADLAePDGRFDLI-VAADVLTYL---GDLAAVFAGVARALKPG-GLFIFSVEDAD 148
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
35-134 3.47e-22

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 87.19  E-value: 3.47e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  35 STILDIGCGTGSFTSKL---NDFDCITGMDLSVDMLSIAMQKSSEVNWIEGDMTDFDLNQQFDVItIFCDSLNYLTEYED 111
Cdd:COG4106    3 RRVLDLGCGTGRLTALLaerFPGARVTGVDLSPEMLARARARLPNVRFVVADLRDLDPPEPFDLV-VSNAALHWLPDHAA 81

                         90       100
                 ....*....|....*....|...
gi 808046148 112 VlstFQQVYHHLEPNeGIFMFDV 134
Cdd:COG4106   82 L---LARLAAALAPG-GVLAVQV 100
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 15-134 1.16e-18

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 78.91  E-value: 1.16e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  15 TLDQPYESW----LDIVEFYAKNKSTILDIGCGTGSFTSKLNDFDC-ITGMDLSVDMLSIAMQKSSEVN--WIEGDMTDF 87
Cdd:COG2227    2 SDPDARDFWdrrlAALLARLLPAGGRVLDVGCGTGRLALALARRGAdVTGVDISPEALEIARERAAELNvdFVQGDLEDL 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 808046148  88 DL-NQQFDVItIFCDSLNYLteyEDVLSTFQQVYHHLEPNeGIFMFDV 134
Cdd:COG2227   82 PLeDGSFDLV-ICSEVLEHL---PDPAALLRELARLLKPG-GLLLLST 124
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 37-126 5.39e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 76.06  E-value: 5.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   37 ILDIGCGTGSFTSKL-NDFDC-ITGMDLSVDMLSIAMQKSSE----VNWIEGDMTDFDL-NQQFDVITIFCdSLNYLTEy 109
Cdd:pfam13649   1 VLDLGCGTGRLTLALaRRGGArVTGVDLSPEMLERARERAAEaglnVEFVQGDAEDLPFpDGSFDLVVSSG-VLHHLPD- 78

                          90
                  ....*....|....*..
gi 808046148  110 EDVLSTFQQVYHHLEPN 126
Cdd:pfam13649  79 PDLEAALREIARVLKPG 95
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 4-143 2.89e-17

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 75.80  E-value: 2.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   4 YEEMSYYYDQltldqpYESWLDIVEfyAKNKSTILDIGCGTGSFTSKLNDFDC-ITGMDLSVDMLSIAMQKSSE----VN 78
Cdd:COG2226    1 FDRVAARYDG------REALLAALG--LRPGARVLDLGCGTGRLALALAERGArVTGVDISPEMLELARERAAEaglnVE 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 808046148  79 WIEGDMTDFDL-NQQFDVITIFCdSLNYLteyEDVLSTFQQVYHHLEPNeGIFMFDVHTEHKMNTL 143
Cdd:COG2226   73 FVVGDAEDLPFpDGSFDLVISSF-VLHHL---PDPERALAEIARVLKPG-GRLVVVDFSPPDLAEL 133
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 38-132 1.24e-11

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 59.22  E-value: 1.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   38 LDIGCGTGSFTSKLNDFDC-ITGMDLSVDMLSIAMQKSSE--VNWIEGDMTDFDL-NQQFDVITIFcDSLNYLteyEDVL 113
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGArVTGVDISPEMLELAREKAPRegLTFVVGDAEDLPFpDNSFDLVLSS-EVLHHV---EDPE 76

                          90
                  ....*....|....*....
gi 808046148  114 STFQQVYHHLEPNeGIFMF 132
Cdd:pfam08241  77 RALREIARVLKPG-GILII 94
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 38-130 1.86e-11

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 58.92  E-value: 1.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   38 LDIGCGTGSFTSKL---NDFDCITGMDLSVDMLSIAMQK--------SSEVNWIEGDMTDFDLNqQFDVITIfCDSLNYL 106
Cdd:pfam08242   1 LEIGCGTGTLLRALleaLPGLEYTGLDISPAALEAARERlaalgllnAVRVELFQLDLGELDPG-SFDVVVA-SNVLHHL 78

                          90       100
                  ....*....|....*....|....
gi 808046148  107 teyEDVLSTFQQVYHHLEPNeGIF 130
Cdd:pfam08242  79 ---ADPRAVLRNIRRLLKPG-GVL 98
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 23-152 1.48e-10

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 57.82  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   23 WLDIVEFYAKNKST---ILDIGCGTGSFTSKLNDFDC-ITGMDLSVDMLSIAMQKSSEVNwiEGDMTDFDLNQQFDVITi 98
Cdd:pfam13489   9 LADLLLRLLPKLPSpgrVLDFGCGTGIFLRLLRAQGFsVTGVDPSPIAIERALLNVRFDQ--FDEQEAAVPAGKFDVIV- 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 808046148   99 fcdsLNYLTEY-EDVLSTFQQVYHHLEPNeGIFMFDVHT-EHKMNTLFNNQSYIDE 152
Cdd:pfam13489  86 ----AREVLEHvPDPPALLRQIAALLKPG-GLLLLSTPLaSDEADRLLLEWPYLRP 136
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 35-132 1.79e-10

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 57.63  E-value: 1.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  35 STILDIGCGTGSFTSKLND-FDC-ITGMDLSVDMLSIAMQKSSE------VNWIEGDMTDFDLNQQFDVItIFCDSLNYL 106
Cdd:COG2230   53 MRVLDIGCGWGGLALYLARrYGVrVTGVTLSPEQLEYARERAAEagladrVEVRLADYRDLPADGQFDAI-VSIGMFEHV 131

                         90       100
                 ....*....|....*....|....*.
gi 808046148 107 TEyEDVLSTFQQVYHHLEPNeGIFMF 132
Cdd:COG2230  132 GP-ENYPAYFAKVARLLKPG-GRLLL 155
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 36-134 1.85e-10

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 56.28  E-value: 1.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  36 TILDIGCGTGSFTSKLNDFDC--ITGMDLSVDMLSIAMQ-----KSSEVNWIEGDMTDFDL--NQQFDVItIFCDSLNYL 106
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGarVTGVDISPVALELARKaaaalLADNVEVLKGDAEELPPeaDESFDVI-ISDPPLHHL 79

                         90       100
                 ....*....|....*....|....*...
gi 808046148 107 teYEDVLSTFQQVYHHLEPNeGIFMFDV 134
Cdd:cd02440   80 --VEDLARFLEEARRLLKPG-GVLVLTL 104
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 8-135 5.89e-10

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 57.23  E-value: 5.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   8 SYYYDQLtldQPYESWLDIVEFYAKNKSTILDIGCGTGSFTSKL--NDFDCITGMDLSVDMLSIAMQKSSE-----VNWI 80
Cdd:COG0500    4 SYYSDEL---LPGLAALLALLERLPKGGRVLDLGCGTGRNLLALaaRFGGRVIGIDLSPEAIALARARAAKaglgnVEFL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 808046148  81 EGDMTDFD--LNQQFDVItIFCDSLNYLTEyEDVLSTFQQVYHHLEPNeGIFMFDVH 135
Cdd:COG0500   81 VADLAELDplPAESFDLV-VAFGVLHHLPP-EEREALLRELARALKPG-GVLLLSAS 134
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 26-132 7.16e-10

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 57.30  E-value: 7.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   26 IVEFYAKNKSTILDIGCGTGSFTSKL---NDFDCITGMDLSVDMLSIAMQKSSE-VNWIEGDMTDFDL-NQQFDVITI-- 98
Cdd:TIGR02072  27 LKEKGIFIPASVLDIGCGTGYLTRALlkrFPQAEFIALDISAGMLAQAKTKLSEnVQFICGDAEKLPLeDSSFDLIVSnl 106

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 808046148   99 ---FCDSLNylteyedvlSTFQQVYHHLEPNeGIFMF 132
Cdd:TIGR02072 107 alqWCDDLS---------QALSELARVLKPG-GLLAF 133
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 31-98 6.49e-09

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 54.39  E-value: 6.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  31 AKNKSTILDIGCGTG----SFTSKLNDFDCITGMDLSVDMLSIAMQK------SSEVNWIEGDMTD--FDlNQQFDVITI 98
Cdd:PRK00216  49 VRPGDKVLDLACGTGdlaiALAKAVGKTGEVVGLDFSEGMLAVGREKlrdlglSGNVEFVQGDAEAlpFP-DNSFDAVTI 127
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 36-131 1.94e-08

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 52.03  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   36 TILDIGCGTGSFTSKLNDFDC----ITGMDLSVDMLSIAMQ-----KSSEVNWIEGDMTDFDLN---QQFDVITIFCdSL 103
Cdd:pfam13847   6 RVLDLGCGTGHLSFELAEELGpnaeVVGIDISEEAIEKAREnaqklGFDNVEFEQGDIEELPELledDKFDVVISNC-VL 84

                          90       100
                  ....*....|....*....|....*...
gi 808046148  104 NYLTEYEDVLSTFQQVyhhLEPNeGIFM 131
Cdd:pfam13847  85 NHIPDPDKVLQEILRV---LKPG-GRLI 108
NodS pfam05401
Nodulation protein S (NodS); This family consists of nodulation S (NodS) proteins. The ...
 35-132 2.07e-07

Nodulation protein S (NodS); This family consists of nodulation S (NodS) proteins. The products of the rhizobial nodulation genes are involved in the biosynthesis of lipochitin oligosaccharides (LCOs), which are host-specific signal molecules required for nodule formation. NodS is an S-adenosyl-L-methionine (SAM)-dependent methyltransferase involved in N methylation of LCOs. NodS uses N-deacetylated chitooligosaccharides, the products of the NodBC proteins, as its methyl acceptors.


Pssm-ID: 428457  Cd Length: 201  Bit Score: 50.01  E-value: 2.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148   35 STILDIGCGTGSFTSKLNDF-DCITGMDLSVDMLSIAMQ---KSSEVNWIEGDMTDFDLNQQFDVItIFCDSLNYLTEYE 110
Cdd:pfam05401  45 ADALEIGCAAGAFTEMLAILcERLTVVDLMPEAIAKAQErtgKWSDIIWHECDICQFDLNAKFDLI-ICAEVLYYIHDKE 123

                          90       100
                  ....*....|....*....|..
gi 808046148  111 DVLSTFQQVYHHLEPnEGIFMF 132
Cdd:pfam05401 124 ELHAAIENIVQLLAP-DEQFIF 144
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
35-96 1.39e-05

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 44.51  E-value: 1.39e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 808046148  35 STILDIGCGTGSFT--SKLNDFDCITGMDLSVDMLSIA----MQKSSEVNWIEGDMTDFDLNQQFDVI 96
Cdd:COG2263   47 KTVLDLGCGTGMLAigAALLGAKKVVGVDIDPEALEIArenaERLGVRVDFIRADVTRIPLGGSVDTV 114
PRK01683 PRK01683
trans-aconitate 2-methyltransferase; Provisional
 37-126 7.82e-04

trans-aconitate 2-methyltransferase; Provisional


Pssm-ID: 234970  Cd Length: 258  Bit Score: 39.54  E-value: 7.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  37 ILDIGCGTGSFTSKLND---FDCITGMDLSVDMLSIAMQKSSEVNWIEGDMTDFDLNQQFDVitIFCD-SLNYLTEYEDV 112
Cdd:PRK01683  35 VVDLGCGPGNSTELLVErwpAARITGIDSSPAMLAEARSRLPDCQFVEADIASWQPPQALDL--IFANaSLQWLPDHLEL 112

                         90
                 ....*....|....
gi 808046148 113 lstFQQVYHHLEPN 126
Cdd:PRK01683 113 ---FPRLVSLLAPG 123
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 31-151 8.33e-04

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 39.49  E-value: 8.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  31 AKNKSTILDIGCGTGSF----TSKLNDFDCITGMDLSVDMLSIAMQKS--------SEVNWIEGDMTDFDLNQ-QFDVIT 97
Cdd:PLN02233  71 AKMGDRVLDLCCGSGDLafllSEKVGSDGKVMGLDFSSEQLAVAASRQelkakscyKNIEWIEGDATDLPFDDcYFDAIT 150

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 808046148  98 IFCDSLNYLteyeDVLSTFQQVYHHLEPNEGIFMFDVHTEHKMNTLFNNQSYID 151
Cdd:PLN02233 151 MGYGLRNVV----DRLKAMQEMYRVLKPGSRVSILDFNKSTQPFTTSMQEWMID 200
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 26-96 2.05e-03

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 38.60  E-value: 2.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  26 IVEFYAKNKSTILDIGCGTG----SFTSKLNDFDcITGMDLSVDMLSIAMQ-----KSSEVNWIEGDMTDFDLNQQFDVI 96
Cdd:PRK09328 101 LEALLLKEPLRVLDLGTGSGaialALAKERPDAE-VTAVDISPEALAVARRnakhgLGARVEFLQGDWFEPLPGGRFDLI 179
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 31-97 2.29e-03

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 38.20  E-value: 2.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  31 AKNKSTILDIGCGTGS---FTSKLNDFDCITGMDLSVDMLSIAmQKSSEVN-W------IEGDMTDF---DLNQQFDVIT 97
Cdd:COG4123   35 VKKGGRVLDLGTGTGVialMLAQRSPGARITGVEIQPEAAELA-RRNVALNgLedritvIHGDLKEFaaeLPPGSFDLVV 113
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 36-96 3.00e-03

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 37.82  E-value: 3.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  36 TILDIGCGTGsftsklndfdCI-------------TGMDLSVDMLSIAMQ------KSSEVNWIEGDMTD-FDLNQQFDV 95
Cdd:COG2890  115 RVLDLGTGSG----------AIalalakerpdarvTAVDISPDALAVARRnaerlgLEDRVRFLQGDLFEpLPGDGRFDL 184


                 .
gi 808046148  96 I 96
Cdd:COG2890  185 I 185
PLN02232 PLN02232
ubiquinone biosynthesis methyltransferase
 59-151 4.49e-03

ubiquinone biosynthesis methyltransferase


Pssm-ID: 165876  Cd Length: 160  Bit Score: 36.59  E-value: 4.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808046148  59 GMDLSVDMLSIAMQKSSE--------VNWIEGDMTDFDLNQ-QFDVITIFCDSLNYLteyeDVLSTFQQVYHHLEPNEGI 129
Cdd:PLN02232   2 GLDFSSEQLAVAATRQSLkarscykcIEWIEGDAIDLPFDDcEFDAVTMGYGLRNVV----DRLRAMKEMYRVLKPGSRV 77

                         90       100
                 ....*....|....*....|..
gi 808046148 130 FMFDVHTEHKMNTLFNNQSYID 151
Cdd:PLN02232  78 SILDFNKSNQSVTTFMQGWMID 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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