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Conserved domains on  [gi|806465039|ref|WP_046128056|]
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MULTISPECIES: plasmid replication DNA-binding protein [Acinetobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
rep_pAB02_ORF2 super family cl45742
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-185 8.94e-61

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


The actual alignment was detected with superfamily member NF038291:

Pssm-ID: 468456  Cd Length: 172  Bit Score: 186.77  E-value: 8.94e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039   2 AKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRCFGEP------EQTSQKIESSKQEGDESTKKLIAHLE 75
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFGEPskkstdVNTSQSINSQKSTEVELLKQQVDMLK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039  76 NEVKKYQEREERLMQQIDRMQTLIELKSVAPATALPQQDATACDTDMPQHATTQQDNDnkknnefniaenVAVPQQETTA 155
Cdd:NF038291  81 KQLEQAKERESFYQKQIDDLQLLLEYKAPKPNMTTFTDQPEANDTATDPQPETEQKHD------------GLTTPEETEN 148

                        170       180       190
                 ....*....|....*....|....*....|
gi 806465039 156 YHTQTLQHATlqnvavPQHKKRGLFGRVLN 185
Cdd:NF038291 149 KRIPVPEHVE------PEPKKRGLFGRFFG 172
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-185 8.94e-61

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 186.77  E-value: 8.94e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039   2 AKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRCFGEP------EQTSQKIESSKQEGDESTKKLIAHLE 75
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFGEPskkstdVNTSQSINSQKSTEVELLKQQVDMLK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039  76 NEVKKYQEREERLMQQIDRMQTLIELKSVAPATALPQQDATACDTDMPQHATTQQDNDnkknnefniaenVAVPQQETTA 155
Cdd:NF038291  81 KQLEQAKERESFYQKQIDDLQLLLEYKAPKPNMTTFTDQPEANDTATDPQPETEQKHD------------GLTTPEETEN 148

                        170       180       190
                 ....*....|....*....|....*....|
gi 806465039 156 YHTQTLQHATlqnvavPQHKKRGLFGRVLN 185
Cdd:NF038291 149 KRIPVPEHVE------PEPKKRGLFGRFFG 172
HTH_17 pfam12728
Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.
 4-29 4.39e-03

Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.


Pssm-ID: 463684 [Multi-domain]  Cd Length: 51  Bit Score: 33.97  E-value: 4.39e-03
                          10        20
                  ....*....|....*....|....*.
gi 806465039    4 LSLSEVSKKFHVDRSTIYRAVRNGRL 29
Cdd:pfam12728   2 LTVEEAAELLGVSRRTVYRLIRSGEL 27
 
Name Accession Description Interval E-value
rep_pAB02_ORF2 NF038291
plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal ...
 2-185 8.94e-61

plasmid replication DNA-binding protein; This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.


Pssm-ID: 468456  Cd Length: 172  Bit Score: 186.77  E-value: 8.94e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039   2 AKLSLSEVSKKFHVDRSTIYRAVRNGRLSRSSDGQFDLAEVIRCFGEP------EQTSQKIESSKQEGDESTKKLIAHLE 75
Cdd:NF038291   1 AKLSVSEASKLFNISRSTIYKAIKKGDLSKDSDGLIDLSEAIRVFGEPskkstdVNTSQSINSQKSTEVELLKQQVDMLK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806465039  76 NEVKKYQEREERLMQQIDRMQTLIELKSVAPATALPQQDATACDTDMPQHATTQQDNDnkknnefniaenVAVPQQETTA 155
Cdd:NF038291  81 KQLEQAKERESFYQKQIDDLQLLLEYKAPKPNMTTFTDQPEANDTATDPQPETEQKHD------------GLTTPEETEN 148

                        170       180       190
                 ....*....|....*....|....*....|
gi 806465039 156 YHTQTLQHATlqnvavPQHKKRGLFGRVLN 185
Cdd:NF038291 149 KRIPVPEHVE------PEPKKRGLFGRFFG 172
HTH_17 pfam12728
Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.
 4-29 4.39e-03

Helix-turn-helix domain; This domain is a DNA-binding helix-turn-helix domain.


Pssm-ID: 463684 [Multi-domain]  Cd Length: 51  Bit Score: 33.97  E-value: 4.39e-03
                          10        20
                  ....*....|....*....|....*.
gi 806465039    4 LSLSEVSKKFHVDRSTIYRAVRNGRL 29
Cdd:pfam12728   2 LTVEEAAELLGVSRRTVYRLIRSGEL 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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