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Conserved domains on  [gi|786014722|ref|WP_045725246|]
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MULTISPECIES: ATP-binding protein [Clostridium]

Protein Classification

ATP-binding protein( domain architecture ID 11482438)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to DnaC which is a loading factor that complexes with the C-terminus of helicase dnaB and inhibits it from unwinding the dsDNA at a replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 1-326 7.57e-139

DNA replication protein DnaC; Validated


:

Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 396.19  E-value: 7.57e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722   1 MIKGYQSELMDVYQKIRANEEKQLRERRAEIKALYPQILELDNEIHKLSLKLTMTILKANT-TEEDIEKIKDEITDLRAK 79
Cdd:PRK06835   1 MIKGYISEILKEYEKRRDKEELELKNRKEEVYKKIPEIAEIDDEIAKLGIKLSRAILKNPDkKEETLKELKEKITDLRVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  80 KCEALVERGYSPEYLNMHYRCNKCQDTGYIGVEKCDCYKDKLVKLYYKDSELQEILKDNNFSKFNIDLFSSsREDSREKY 159
Cdd:PRK06835  81 KAELLVSNGYPPDYLEMKYTCPKCKDTGFINGKKCSCYKQKLINLYYKQSNLKEILKEENFSNFNLNYYSD-EKDDDEPL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 160 SAKTNMKNNLNfIMKDFIPNFSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNNNEYLE 239
Cdd:PRK06835 160 SPRKNMEKILE-KCKNFIENFDKNNENLLFYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILREIRFNNDKELE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 240 ---KLLIDCDLLIIDDLGSEQLNDFAATELFNLINRKLLKKKKMLISTNFTLADLAKHYSERISSRLLGNFKLQKFYSDD 316
Cdd:PRK06835 239 evyDLLINCDLLIIDDLGTEKITEFSKSELFNLINKRLLRQKKMIISTNLSLEELLKTYSERISSRLLGNFTLLKFYGED 318

                        330
                 ....*....|
gi 786014722 317 IRIKLNLSKR 326
Cdd:PRK06835 319 IRIKKNLQKK 328
 
Name Accession Description Interval E-value
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 1-326 7.57e-139

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 396.19  E-value: 7.57e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722   1 MIKGYQSELMDVYQKIRANEEKQLRERRAEIKALYPQILELDNEIHKLSLKLTMTILKANT-TEEDIEKIKDEITDLRAK 79
Cdd:PRK06835   1 MIKGYISEILKEYEKRRDKEELELKNRKEEVYKKIPEIAEIDDEIAKLGIKLSRAILKNPDkKEETLKELKEKITDLRVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  80 KCEALVERGYSPEYLNMHYRCNKCQDTGYIGVEKCDCYKDKLVKLYYKDSELQEILKDNNFSKFNIDLFSSsREDSREKY 159
Cdd:PRK06835  81 KAELLVSNGYPPDYLEMKYTCPKCKDTGFINGKKCSCYKQKLINLYYKQSNLKEILKEENFSNFNLNYYSD-EKDDDEPL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 160 SAKTNMKNNLNfIMKDFIPNFSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNNNEYLE 239
Cdd:PRK06835 160 SPRKNMEKILE-KCKNFIENFDKNNENLLFYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILREIRFNNDKELE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 240 ---KLLIDCDLLIIDDLGSEQLNDFAATELFNLINRKLLKKKKMLISTNFTLADLAKHYSERISSRLLGNFKLQKFYSDD 316
Cdd:PRK06835 239 evyDLLINCDLLIIDDLGTEKITEFSKSELFNLINKRLLRQKKMIISTNLSLEELLKTYSERISSRLLGNFTLLKFYGED 318

                        330
                 ....*....|
gi 786014722 317 IRIKLNLSKR 326
Cdd:PRK06835 319 IRIKKNLQKK 328
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
186-304 6.43e-17

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 78.67  E-value: 6.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQLNDFAA 263
Cdd:COG1484  101 NLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELK-EARADGRLERLLkrLAKVDLLILDELGYLPLDAEGA 179

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 786014722 264 TELFNLINRkLLKKKKMLISTNFTLADLAKHYSE-----RISSRLL 304
Cdd:COG1484  180 ELLFELISD-RYERRSTIITSNLPFSEWGEVFGDptlatAILDRLV 224
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 186-272 1.60e-11

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 63.26  E-value: 1.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQLNDFAA 263
Cdd:NF038214  92 NVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLA-QARADGRLGRLLrrLARYDLLIIDELGYLPFSREGA 170


                 ....*....
gi 786014722 264 TELFNLINR 272
Cdd:NF038214 171 NLLFELIAD 179
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 180-289 3.38e-08

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 53.60  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  180 FSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQ 257
Cdd:pfam01695  88 FIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLK-RAHGDGKLTRKLqqLLKPDVLILDEWGYLP 166

                          90       100       110
                  ....*....|....*....|....*....|..
gi 786014722  258 LNDFAATELFNLINRkLLKKKKMLISTNFTLA 289
Cdd:pfam01695 167 LDQAEANLLFQVISK-RYEHRSIILTSNLPFG 197
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 186-303 7.98e-07

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 47.91  E-value: 7.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNNNEYLEKLLIDC-----DLLIIDDLGSeqLND 260
Cdd:cd00009   21 NLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELAekakpGVLFIDEIDS--LSR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 786014722 261 FAATELFNLINRKLLKKKK------MLISTNFTLADLAKHYSERISSRL 303
Cdd:cd00009   99 GAQNALLRVLETLNDLRIDrenvrvIGATNRPLLGDLDRALYDRLDIRI 147
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 187-271 8.42e-04

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 40.98  E-value: 8.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  187 LLFYGTAGSGKTFLSYCIAKELLDR--GYLVVYKTSD----ELIRALRDikfNNNEYLEKLLIDCDLLIIDDL----GSE 256
Cdd:TIGR00362 140 LFIYGGVGLGKTHLLHAIGNEILENnpNAKVLYVSSEkftnDFVNALRN---NKMEEFKEKYRSVDLLLIDDIqflaGKE 216

                          90
                  ....*....|....*
gi 786014722  257 QLNdfaaTELFNLIN 271
Cdd:TIGR00362 217 RTQ----EEFFHTFN 227
 
Name Accession Description Interval E-value
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 1-326 7.57e-139

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 396.19  E-value: 7.57e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722   1 MIKGYQSELMDVYQKIRANEEKQLRERRAEIKALYPQILELDNEIHKLSLKLTMTILKANT-TEEDIEKIKDEITDLRAK 79
Cdd:PRK06835   1 MIKGYISEILKEYEKRRDKEELELKNRKEEVYKKIPEIAEIDDEIAKLGIKLSRAILKNPDkKEETLKELKEKITDLRVK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  80 KCEALVERGYSPEYLNMHYRCNKCQDTGYIGVEKCDCYKDKLVKLYYKDSELQEILKDNNFSKFNIDLFSSsREDSREKY 159
Cdd:PRK06835  81 KAELLVSNGYPPDYLEMKYTCPKCKDTGFINGKKCSCYKQKLINLYYKQSNLKEILKEENFSNFNLNYYSD-EKDDDEPL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 160 SAKTNMKNNLNfIMKDFIPNFSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNNNEYLE 239
Cdd:PRK06835 160 SPRKNMEKILE-KCKNFIENFDKNNENLLFYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILREIRFNNDKELE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 240 ---KLLIDCDLLIIDDLGSEQLNDFAATELFNLINRKLLKKKKMLISTNFTLADLAKHYSERISSRLLGNFKLQKFYSDD 316
Cdd:PRK06835 239 evyDLLINCDLLIIDDLGTEKITEFSKSELFNLINKRLLRQKKMIISTNLSLEELLKTYSERISSRLLGNFTLLKFYGED 318

                        330
                 ....*....|
gi 786014722 317 IRIKLNLSKR 326
Cdd:PRK06835 319 IRIKKNLQKK 328
PRK08116 PRK08116
hypothetical protein; Validated
 118-304 3.59e-26

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 104.72  E-value: 3.59e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 118 KDKLVKLYYKDSELQEILKDNNFSKFNIDLFSSSREDSREKYSAK-TNMKnnlnfimkdfipnfsKSSDNLLFYGTAGSG 196
Cdd:PRK08116  62 KQRRIERLKSNSLLDEKFRNSTFENFLFDKGSEKAYKIARKYVKKfEEMK---------------KENVGLLLWGSVGTG 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 197 KTFLSYCIAKELLDRGYLVVYKTSDELIRALRDI-----KFNNNEYLEKLlIDCDLLIIDDLGSEQLNDFAATELFNLIN 271
Cdd:PRK08116 127 KTYLAACIANELIEKGVPVIFVNFPQLLNRIKSTykssgKEDENEIIRSL-VNADLLILDDLGAERDTEWAREKVYNIID 205

                        170       180       190
                 ....*....|....*....|....*....|...
gi 786014722 272 RKLLKKKKMLISTNFTLADLAKHYSERISSRLL 304
Cdd:PRK08116 206 SRYRKGLPTIVTTNLSLEELKNQYGKRIYDRIL 238
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
186-304 6.43e-17

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 78.67  E-value: 6.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQLNDFAA 263
Cdd:COG1484  101 NLILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNELK-EARADGRLERLLkrLAKVDLLILDELGYLPLDAEGA 179

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 786014722 264 TELFNLINRkLLKKKKMLISTNFTLADLAKHYSE-----RISSRLL 304
Cdd:COG1484  180 ELLFELISD-RYERRSTIITSNLPFSEWGEVFGDptlatAILDRLV 224
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 186-272 1.60e-11

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 63.26  E-value: 1.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQLNDFAA 263
Cdd:NF038214  92 NVLLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLA-QARADGRLGRLLrrLARYDLLIIDELGYLPFSREGA 170


                 ....*....
gi 786014722 264 TELFNLINR 272
Cdd:NF038214 171 NLLFELIAD 179
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
187-303 2.29e-08

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 54.43  E-value: 2.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 187 LLFYGTAGSGKTFLSYCIAKELLDR--GYLVVYKTSDELIRALRD-IKFNNNEYLEKLLIDCDLLIIDDLGSEQLNDFAA 263
Cdd:COG0593   37 LFLYGGVGLGKTHLLHAIGNEALENnpGARVVYLTAEEFTNDFINaIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQ 116

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 786014722 264 TELFNLINRKLLKKKKMLISTNFTLADLAKHySERISSRL 303
Cdd:COG0593  117 EEFFHTFNALREAGKQIVLTSDRPPKELPGL-EERLRSRL 155
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 180-289 3.38e-08

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 53.60  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  180 FSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRdIKFNNNEYLEKL--LIDCDLLIIDDLGSEQ 257
Cdd:pfam01695  88 FIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLK-RAHGDGKLTRKLqqLLKPDVLILDEWGYLP 166

                          90       100       110
                  ....*....|....*....|....*....|..
gi 786014722  258 LNDFAATELFNLINRkLLKKKKMLISTNFTLA 289
Cdd:pfam01695 167 LDQAEANLLFQVISK-RYEHRSIILTSNLPFG 197
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 155-306 5.17e-08

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 52.85  E-value: 5.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 155 SREKYSAKTNMKNNLNFIMKDFIPNFSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNN 234
Cdd:PRK07952  70 SFENYRVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNS 149

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 786014722 235 NEYLEKLLID---CDLLIIDDLGSEQLNDFAATELFNLINRKLLKKKKMLISTNFTLADLAKHYSERISSRL-LGN 306
Cdd:PRK07952 150 ETSEEQLLNDlsnVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMrLGN 225
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 186-303 7.98e-07

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 47.91  E-value: 7.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDIKFNNNEYLEKLLIDC-----DLLIIDDLGSeqLND 260
Cdd:cd00009   21 NLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFELAekakpGVLFIDEIDS--LSR 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 786014722 261 FAATELFNLINRKLLKKKK------MLISTNFTLADLAKHYSERISSRL 303
Cdd:cd00009   99 GAQNALLRVLETLNDLRIDrenvrvIGATNRPLLGDLDRALYDRLDIRI 147
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
 78-297 7.45e-06

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 46.78  E-value: 7.45e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  78 AKKCEALVErGYSPE-YLNMHY---RCNKCQDTgyIGVEKCDCYKdKLVKLYYkdseLQEILKDNNFSKFNIDlfsssrE 153
Cdd:PRK08939  68 DRGCPNYAK-GYQPKlVMNGGYidvSYLPTPEK--IEADEEKAIK-KRIQSIY----MPKDLLQASLADIDLD------D 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 154 DSREKYSAKTNmknnlnfimkDFIPNFSKSSD--NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIralRDIK 231
Cdd:PRK08939 134 RDRLDALMAAL----------DFLEAYPPGEKvkGLYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFPEFI---RELK 200

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 786014722 232 --FNNNEYLEKL--LIDCDLLIIDDLGSEQLNDFAATELFNLInrkllKKKKML------ISTNFTLADLAKHYSE 297
Cdd:PRK08939 201 nsISDGSVKEKIdaVKEAPVLMLDDIGAEQMSSWVRDEVLGVI-----LQYRMQeelptfFTSNFDFDELEHHLAY 271
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
186-270 2.01e-05

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 44.91  E-value: 2.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 186 NLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDE----LIRALRDIKFNnneyLEKLLIDCDLLIIDDLGSEQLNDF 261
Cdd:COG0467   22 STLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEEspeqLLRRAESLGLD----LEEYIESGLLRIIDLSPEELGLDL 97


                 ....*....
gi 786014722 262 aaTELFNLI 270
Cdd:COG0467   98 --EELLARL 104
Bac_DnaA pfam00308
Bacterial dnaA protein;
187-271 7.17e-05

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 43.47  E-value: 7.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  187 LLFYGTAGSGKTFLSYCIAKELLD--RGYLVVYKTSDE----LIRALRDikfNNNEYLEKLLIDCDLLIIDDL----GSE 256
Cdd:pfam00308  37 LFIYGGVGLGKTHLLHAIGNYALQnaPNLRVVYLTAEEflndFVDAIRD---NKTNQFKEKYRNVDVLLIDDIqflaGKE 113

                          90
                  ....*....|....*
gi 786014722  257 QLNdfaaTELFNLIN 271
Cdd:pfam00308 114 GTQ----EEFFHTFN 124
PRK08181 PRK08181
transposase; Validated
 185-271 4.77e-04

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 41.07  E-value: 4.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 185 DNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRAL----RDIKFNNN-EYLEKLlidcDLLIIDDLGSEQLN 259
Cdd:PRK08181 107 ANLLLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLqvarRELQLESAiAKLDKF----DLLILDDLAYVTKD 182

                         90
                 ....*....|..
gi 786014722 260 DFAATELFNLIN 271
Cdd:PRK08181 183 QAETSVLFELIS 194
dnaA PRK00149
chromosomal replication initiator protein DnaA;
187-271 4.99e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 41.66  E-value: 4.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722 187 LLFYGTAGSGKTFLSYCIAKELLDR--GYLVVYKTSD----ELIRALRDikfNNNEYLEKLLIDCDLLIIDDL----GSE 256
Cdd:PRK00149 102 LFIYGGVGLGKTHLLHAIGNYILEKnpNAKVVYVTSEkftnDFVNALRN---NTMEEFKEKYRSVDVLLIDDIqflaGKE 178

                         90
                 ....*....|....*
gi 786014722 257 QLNDfaatELFNLIN 271
Cdd:PRK00149 179 RTQE----EFFHTFN 189
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 187-271 8.42e-04

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 40.98  E-value: 8.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  187 LLFYGTAGSGKTFLSYCIAKELLDR--GYLVVYKTSD----ELIRALRDikfNNNEYLEKLLIDCDLLIIDDL----GSE 256
Cdd:TIGR00362 140 LFIYGGVGLGKTHLLHAIGNEILENnpNAKVLYVSSEkftnDFVNALRN---NKMEEFKEKYRSVDLLLIDDIqflaGKE 216

                          90
                  ....*....|....*
gi 786014722  257 QLNdfaaTELFNLIN 271
Cdd:TIGR00362 217 RTQ----EEFFHTFN 227
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 180-263 9.47e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 36.33  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 786014722  180 FSKSSDNLLFYGTAGSGKTFLSYCIAKELLDRGYLVVYKTSDELIRALRDI-KFNNNEYLEKLL--------------ID 244
Cdd:pfam13191  20 RSGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLeALTREGLLRQLLdelesslleawraaLL 99

                          90
                  ....*....|....*....
gi 786014722  245 CDLLIIDDLGSEQLNDFAA 263
Cdd:pfam13191 100 EALAPVPELPGDLAERLLD 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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