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Conserved domains on  [gi|779839602|ref|WP_045343953|]
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MULTISPECIES: type IV conjugative transfer system pilin TraA [Enterobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TraA super family cl11503
TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced ...
 18-116 6.05e-11

TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced in response to a peptide sex pheromone, cPD1, secreted from plasmid-free recipient cells. cPD1 is taken up by a pPD1 donor cell and binds to an intracellular receptor, TraA. Once a recipient cell acquires pPD1, it starts to produce an inhibitor of cPD1, termed iPD1, which functions as a TraA antagonist and blocks self-induction in donor cells. TraA transduces the signal of cPD1 to the mating response.


The actual alignment was detected with superfamily member PRK13734:

Pssm-ID: 299752  Cd Length: 120  Bit Score: 55.32  E-value: 6.05e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779839602  18 SLFRKARENRLTKFYLKtVGAFLFAFLVTHPAFASGTDLLASQNTTVNSTFGSGSSIVKWFYLGEILFGVFIYMKTRSPL 97
Cdd:PRK13734  21 SKFTRLNMLRLARAVIP-VAVLMMFFPQLAMAGAGGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVK 99

                         90
                 ....*....|....*....
gi 779839602  98 TFLGVPLVIIATRIGFAIA 116
Cdd:PRK13734 100 FLAGFAIISVFIAVGMSVV 118
 
Name Accession Description Interval E-value
PRK13734 PRK13734
conjugal transfer pilin subunit TraA; Provisional
 18-116 6.05e-11

conjugal transfer pilin subunit TraA; Provisional


Pssm-ID: 237485  Cd Length: 120  Bit Score: 55.32  E-value: 6.05e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779839602  18 SLFRKARENRLTKFYLKtVGAFLFAFLVTHPAFASGTDLLASQNTTVNSTFGSGSSIVKWFYLGEILFGVFIYMKTRSPL 97
Cdd:PRK13734  21 SKFTRLNMLRLARAVIP-VAVLMMFFPQLAMAGAGGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVK 99

                         90
                 ....*....|....*....
gi 779839602  98 TFLGVPLVIIATRIGFAIA 116
Cdd:PRK13734 100 FLAGFAIISVFIAVGMSVV 118
TraA pfam05513
TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced ...
 36-116 3.11e-09

TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced in response to a peptide sex pheromone, cPD1, secreted from plasmid-free recipient cells. cPD1 is taken up by a pPD1 donor cell and binds to an intracellular receptor, TraA. Once a recipient cell acquires pPD1, it starts to produce an inhibitor of cPD1, termed iPD1, which functions as a TraA antagonist and blocks self-induction in donor cells. TraA transduces the signal of cPD1 to the mating response.


Pssm-ID: 283228  Cd Length: 120  Bit Score: 50.82  E-value: 3.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779839602   36 VGAFLFAFLVTHPAFASGTDLLASQNTTVNSTFGSGSSIVKWFYLGEILFGVFIYMKTRSPLTFLGVPLVIIATRIGFAI 115
Cdd:pfam05513  40 AAALAAFFPDAAMAAGGAQDLMASGDATVKATFGKDSSAVKWVILAEVLAGAIMYMMTKNVKFLAGFAIISTFIAIGMAV 119


                  .
gi 779839602  116 A 116
Cdd:pfam05513 120 A 120
 
Name Accession Description Interval E-value
PRK13734 PRK13734
conjugal transfer pilin subunit TraA; Provisional
 18-116 6.05e-11

conjugal transfer pilin subunit TraA; Provisional


Pssm-ID: 237485  Cd Length: 120  Bit Score: 55.32  E-value: 6.05e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779839602  18 SLFRKARENRLTKFYLKtVGAFLFAFLVTHPAFASGTDLLASQNTTVNSTFGSGSSIVKWFYLGEILFGVFIYMKTRSPL 97
Cdd:PRK13734  21 SKFTRLNMLRLARAVIP-VAVLMMFFPQLAMAGAGGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVK 99

                         90
                 ....*....|....*....
gi 779839602  98 TFLGVPLVIIATRIGFAIA 116
Cdd:PRK13734 100 FLAGFAIISVFIAVGMSVV 118
TraA pfam05513
TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced ...
 36-116 3.11e-09

TraA; Conjugative transfer of a bacteriocin plasmid, pPD1, of Enterococcus faecalis is induced in response to a peptide sex pheromone, cPD1, secreted from plasmid-free recipient cells. cPD1 is taken up by a pPD1 donor cell and binds to an intracellular receptor, TraA. Once a recipient cell acquires pPD1, it starts to produce an inhibitor of cPD1, termed iPD1, which functions as a TraA antagonist and blocks self-induction in donor cells. TraA transduces the signal of cPD1 to the mating response.


Pssm-ID: 283228  Cd Length: 120  Bit Score: 50.82  E-value: 3.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779839602   36 VGAFLFAFLVTHPAFASGTDLLASQNTTVNSTFGSGSSIVKWFYLGEILFGVFIYMKTRSPLTFLGVPLVIIATRIGFAI 115
Cdd:pfam05513  40 AAALAAFFPDAAMAAGGAQDLMASGDATVKATFGKDSSAVKWVILAEVLAGAIMYMMTKNVKFLAGFAIISTFIAIGMAV 119


                  .
gi 779839602  116 A 116
Cdd:pfam05513 120 A 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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