|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
1-558 |
0e+00 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 1056.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 1 MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPN 80
Cdd:PRK04972 1 MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 81 FFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESAQLSRALDNLS 160
Cdd:PRK04972 81 FFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGAESRQLSLALDNLS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDTNRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYR 240
Cdd:PRK04972 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDAQRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 241 ATGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLA 320
Cdd:PRK04972 241 QTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGKRLS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 321 QLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMIT 400
Cdd:PRK04972 321 QLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMIT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 401 FQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLGAIGGQMLIAGL 480
Cdd:PRK04972 401 FQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNGLGAVGGQMLIAGL 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757782656 481 IVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIIIIWP 558
Cdd:PRK04972 481 IVSLVPVVICFLFGAYVLRMNRALLFGAIMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIVWP 558
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
3-557 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 532.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 3 INVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGnSIGVLVVSLLLGQQHFS--INTDALNLGFMLFIFCVGVEAGPN 80
Cdd:COG2985 1 MELFELLVANPELALFLVIALGYLLGKIKIGGFSLG-VAGVLFVGLLIGHFGVTlhIPHFVKSLGLALFVYAIGLQVGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 81 FFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESaqlsRALDNLS 160
Cdd:COG2985 80 FFASLKRDGLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSK----QLSANPA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERgldtdtNRKVYLPVIRAYRVGpelVAWTDGKNLRELGIYR 240
Cdd:COG2985 156 VGYAVAYPFGVIGIILFVALLPKLFRIDLDAEAKKLEAGE------GSAYPPLVTRAYRVT---NPNLVGKTVAELEALL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 241 ATGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLdpSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLA 320
Cdd:COG2985 227 GTRVVISRIRRGGEIIVPTPDTVLQEGDIVLVVGTREALEAA--EALLGEEVDDSELLDSDLDVRRIVVTNKEVAGKTLG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 321 QLKL-TDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMI 399
Cdd:COG2985 305 ELNLrNRFGVVITRVRRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSI 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 400 TFQFSNF-SFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLGAIGGQMLIA 478
Cdd:COG2985 385 PIPLPGIpPLSLGLAGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQESGLLLFLL 464
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782656 479 GLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIIIIW 557
Cdd:COG2985 465 GALVTLVPLLVVLLVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
390-541 |
2.26e-45 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 157.11 E-value: 2.26e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 390 FIIGLMIGMITFQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLG 469
Cdd:TIGR01625 1 LALGLLLGKIPIGLPGFSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782656 470 AIGGQMLI-AGLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTAR-SNIPALGYAGTYAI 541
Cdd:TIGR01625 81 DGGGLLRInGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
385-554 |
2.28e-42 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 149.26 E-value: 2.28e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 385 AFCAFFIIGLMIGMITFQFSnfsFGIGNAAGLLFAGIMLGFLRANHPTFgyIPQGALNMVKEFGLMVFMAGVGLSAGSGI 464
Cdd:pfam06826 1 ALFLGIALGLLLGRIKISGG---FSLGVAGGVLIVGLLLGHFGSTGPTF--MPISALSFLRELGLALFLAAVGLSAGPGF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 465 GQGLGAIGGQMLIAGLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDT-ARSNIPALGYAGTYAIAN 543
Cdd:pfam06826 76 FSSLKKDGLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDAlAGSDIPALGYAVTYPFGV 155
|
170
....*....|.
gi 757782656 544 VLLTLAGTLII 554
Cdd:pfam06826 156 VGLILAGQVLA 166
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
1-558 |
0e+00 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 1056.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 1 MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPN 80
Cdd:PRK04972 1 MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 81 FFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESAQLSRALDNLS 160
Cdd:PRK04972 81 FFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGAESRQLSLALDNLS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDTNRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYR 240
Cdd:PRK04972 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDAQRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 241 ATGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLA 320
Cdd:PRK04972 241 QTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGKRLS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 321 QLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMIT 400
Cdd:PRK04972 321 QLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMIT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 401 FQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLGAIGGQMLIAGL 480
Cdd:PRK04972 401 FQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNGLGAVGGQMLIAGL 480
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 757782656 481 IVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIIIIWP 558
Cdd:PRK04972 481 IVSLVPVVICFLFGAYVLRMNRALLFGAIMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIVWP 558
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
3-557 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 532.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 3 INVADLLNGNYILLLFVVLALGLCLGKLRLGSIQLGnSIGVLVVSLLLGQQHFS--INTDALNLGFMLFIFCVGVEAGPN 80
Cdd:COG2985 1 MELFELLVANPELALFLVIALGYLLGKIKIGGFSLG-VAGVLFVGLLIGHFGVTlhIPHFVKSLGLALFVYAIGLQVGPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 81 FFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESaqlsRALDNLS 160
Cdd:COG2985 80 FFASLKRDGLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSK----QLSANPA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 161 LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERgldtdtNRKVYLPVIRAYRVGpelVAWTDGKNLRELGIYR 240
Cdd:COG2985 156 VGYAVAYPFGVIGIILFVALLPKLFRIDLDAEAKKLEAGE------GSAYPPLVTRAYRVT---NPNLVGKTVAELEALL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 241 ATGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLdpSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLA 320
Cdd:COG2985 227 GTRVVISRIRRGGEIIVPTPDTVLQEGDIVLVVGTREALEAA--EALLGEEVDDSELLDSDLDVRRIVVTNKEVAGKTLG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 321 QLKL-TDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMI 399
Cdd:COG2985 305 ELNLrNRFGVVITRVRRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSI 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 400 TFQFSNF-SFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLGAIGGQMLIA 478
Cdd:COG2985 385 PIPLPGIpPLSLGLAGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQESGLLLFLL 464
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757782656 479 GLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIIIIW 557
Cdd:COG2985 465 GALVTLVPLLVVLLVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| PRK03818 |
PRK03818 |
putative transporter; Validated |
14-560 |
1.88e-48 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 176.59 E-value: 1.88e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 14 ILLLFVVLALGLCLGKLRLGSIQLGNSiGVLVVSLLLG----QQHFSINTDALN----LGFMLFIFCVGVEAGPNFFSIF 85
Cdd:PRK03818 8 VSILALVAVVGLWIGNIKIRGVGLGIG-GVLFGGIIVGhfvsQFGLTLDSDMLHfiqeFGLILFVYTIGIQVGPGFFSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 86 FRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESAQlsraLDNLSLGYAL 165
Cdd:PRK03818 87 RKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDL----VDQMGMGYAM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 166 TYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDTNRKVYLPVirayrVGPELvawtDGKNLRELGIYRATGCY 245
Cdd:PRK03818 163 AYPFGICGILLSMWLIRLIFRINVDKEAQEFESSSGNGHELLQTINIRV-----ENPNL----HGKAIKDVPILNGDKFV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 246 IERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFrnGKEVfDRDL--LDMRIVTEEIVVKNHNAVGRRLAQLK 323
Cdd:PRK03818 234 CSRLKRGDTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVI--GEEV-DTSLstRGTDLRSERVVVTNEKVLGKKLRDLH 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 324 LTDH-GCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQ 402
Cdd:PRK03818 311 LKNKyGVVISRLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFF 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 403 FSNFSFGI--GNAAGLLFAGIMLGflranhpTFGYI-------PQGALNMVKEFGLMVFMAGVGLSAGSGI------GQG 467
Cdd:PRK03818 391 IPGFPAALklGLAGGPLIVALILG-------RIGSIgklywfmPPSANLALRELGIVLFLAVVGLKSGGDFvdtlvnGEG 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 468 LGAIGgqmliAGLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISD-TARSNIPALGYAGTYAIANVLL 546
Cdd:PRK03818 464 LSWIG-----YGFLITAVPLLIVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNlHPTSGAAALSYATVYPLVMFLR 538
|
570
....*....|....
gi 757782656 547 TLAGTLIIIIWPGL 560
Cdd:PRK03818 539 IITPQLLAVLFWSL 552
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
390-541 |
2.26e-45 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 157.11 E-value: 2.26e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 390 FIIGLMIGMITFQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGIGQGLG 469
Cdd:TIGR01625 1 LALGLLLGKIPIGLPGFSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 757782656 470 AIGGQMLI-AGLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTAR-SNIPALGYAGTYAI 541
Cdd:TIGR01625 81 DGGGLLRInGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
385-554 |
2.28e-42 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 149.26 E-value: 2.28e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 385 AFCAFFIIGLMIGMITFQFSnfsFGIGNAAGLLFAGIMLGFLRANHPTFgyIPQGALNMVKEFGLMVFMAGVGLSAGSGI 464
Cdd:pfam06826 1 ALFLGIALGLLLGRIKISGG---FSLGVAGGVLIVGLLLGHFGSTGPTF--MPISALSFLRELGLALFLAAVGLSAGPGF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 465 GQGLGAIGGQMLIAGLIVSLVPVIICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDT-ARSNIPALGYAGTYAIAN 543
Cdd:pfam06826 76 FSSLKKDGLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDAlAGSDIPALGYAVTYPFGV 155
|
170
....*....|.
gi 757782656 544 VLLTLAGTLII 554
Cdd:pfam06826 156 VGLILAGQVLA 166
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
16-183 |
2.26e-34 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 127.69 E-value: 2.26e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 16 LLFVVLALGLCLGKLRL-GSIQLGNSIGVLVVSLLLGQQ--------HFSINTDALNLGFMLFIFCVGVEAGPNFFSIFF 86
Cdd:pfam06826 1 ALFLGIALGLLLGRIKIsGGFSLGVAGGVLIVGLLLGHFgstgptfmPISALSFLRELGLALFLAAVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 87 RDGKNYLMLALVMVGSALLIALGLGK-LFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHfgmesaqlsraLDNLSLGYAL 165
Cdd:pfam06826 81 KDGLLLIGLALLVTVVPLLLALVLGKyVLKLDPGLLAGLLAGALTSTPALGAANDALAG-----------SDIPALGYAV 149
|
170
....*....|....*...
gi 757782656 166 TYLIGLVSLIVGARYLPK 183
Cdd:pfam06826 150 TYPFGVVGLILAGQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
21-169 |
2.58e-34 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 127.06 E-value: 2.58e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 21 LALGLCLGKLRLG----SIQLGNSIGVLVVSLLLGQQ----------HFSINTDALNLGFMLFIFCVGVEAGPNFFSIFF 86
Cdd:TIGR01625 1 LALGLLLGKIPIGlpgfSIKLGNAGGVLFVGLLLGHFgatgpltwyiPFSANLFIREFGLMLFLYGVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 87 RDG--KNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHfgmesaqlsraLDNLSLGYA 164
Cdd:TIGR01625 81 DGGglLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRT-----------SDLPALGYA 149
|
....*
gi 757782656 165 LTYLI 169
Cdd:TIGR01625 150 TVYPL 154
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
215-286 |
7.20e-08 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 49.53 E-value: 7.20e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757782656 215 IRAYRVGPElvAWTDGKNLRELGIYRATGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSF 286
Cdd:pfam02080 1 LVEVTVPEN--SPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
147-282 |
9.60e-08 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 51.46 E-value: 9.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 147 MESAQLSRALDNLSLGYALTYLIGLVsLIVGARYLPKLQHQDLQTSAQQIARERGLDTDTNRKVYLPVIRAYRVGPElvA 226
Cdd:COG0490 3 LALLLLLIILLLLLALAALLVAIVIV-GVLGLILRGLLLLELALLLLLLGELLRLLTRLLIELVLLLAIEEVKVPPG--S 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 757782656 227 WTDGKNLRELGIYRATGCYIERIRRNG-ILANPDGDAVLQMGDEIALVGYPDAHARL 282
Cdd:COG0490 80 PLVGKTLGELNLRQRTGVTVVAIRRGGeVILSPGPDTVLEAGDTLVVVGTREQLERL 136
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
303-371 |
6.92e-06 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 43.75 E-value: 6.92e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 303 VTEEIVVKNHNAVGRRLAQLKL-TDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRI 371
Cdd:pfam02080 1 LVEVTVPENSPLVGKTLKELNLpERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| Na_H_Exchanger |
pfam00999 |
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ... |
14-136 |
3.34e-03 |
|
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain] Cd Length: 377 Bit Score: 39.93 E-value: 3.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 14 ILLLFVVLALGLCLGKLRLGSIQLGNSIGVLV-VSLLLGQQHFSINTDAL-NLGFMLFIFCVGVEAGpnfFSIFFRDGKN 91
Cdd:pfam00999 2 VLLILLALLAPLLARRLKLPPIVGLIIAGILLgPSGLGLISEVDEDLEVLsNLGLPPLLFLAGLELD---LRELRKNGGS 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 757782656 92 YLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAG---SMTSTPVLV 136
Cdd:pfam00999 79 ILLLALLGVLIPFVLIGLLLYLLGLGIPLLEALLFGailSATSPVVVL 126
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
229-270 |
4.83e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 39.28 E-value: 4.83e-03
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 757782656 229 DGKNLRELGIYRATGCYIERIRRNGILANPDGDAVLQMGDEI 270
Cdd:COG0569 254 VGKTLKELDLRERYGVTVVAIKRGGEVIIPSGDTVLEAGDEL 295
|
|
| COG3273 |
COG3273 |
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only]; |
214-282 |
7.30e-03 |
|
Uncharacterized protein, contains PhoU and TrkA_C domains [General function prediction only];
Pssm-ID: 442504 [Multi-domain] Cd Length: 387 Bit Score: 38.88 E-value: 7.30e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757782656 214 VIRAYRVGPElvAWTDGKNLRELGIYRATGCYIERIRRNGI-LANPDGDAVLQMGDEIALVGYPDAHARL 282
Cdd:COG3273 314 RIVRVTVPPG--SPLVGKTLGELKLETETGVRVIAIRRGGGwIYDPDGDTRLRAGDVLIVKGTREGLERL 381
|
|
| |
