|
Name |
Accession |
Description |
Interval |
E-value |
| rbsC |
PRK09512 |
ribose ABC transporter permease protein; Reviewed |
2-320 |
2.46e-175 |
|
ribose ABC transporter permease protein; Reviewed
Pssm-ID: 181922 [Multi-domain] Cd Length: 320 Bit Score: 488.07 E-value: 2.46e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 2 SSTTASSKRWFSKAWLMEQKSLIALLILIAIVSTLSPNFFTVNNFFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA 81
Cdd:PRK09512 1 TTQTVSGRRYFTKAWLIEQKSLIALLVLIAIVSTLSPNFFTVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 82 LTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLLLRGVTRVYTDGSPINTGFSDNADLF 161
Cdd:PRK09512 81 LTGAVAASIVGIEVNALVAVPAALALGAAIGAVTGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDGSPINTGFTDNADLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 162 GWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEVAR 241
Cdd:PRK09512 161 GWFGIGRPLGIPTPVWIMAIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKVKIIVYALCGLLAALAGIIEVAR 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757599168 242 LSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKAVVILLAVLVDNKK 320
Cdd:PRK09512 241 LSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK 319
|
|
| AraH |
COG1172 |
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ... |
1-318 |
8.37e-94 |
|
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];
Pssm-ID: 440785 Cd Length: 322 Bit Score: 281.22 E-value: 8.37e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 1 MSSTTASSKRWFSKaWLMEQKSLIALLILIAIVSTLSPNFFTVNNFFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL 80
Cdd:COG1172 1 MSATTTTARSLLRR-LLPELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 81 ALTGAVAAS-MVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLLLRGVTRVYTDGSPIntgfSDNAD 159
Cdd:COG1172 80 ALSGVVAALlLVALGLPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPI----SGLPD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 160 LFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEV 239
Cdd:COG1172 156 AFRALGQGSLLGIPVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLA 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757599168 240 ARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKAVVILLAVLVDN 318
Cdd:COG1172 236 ARLGSAQPNAGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDR 314
|
|
| TM_PBP1_transp_AraH_like |
cd06579 |
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ... |
53-317 |
9.01e-84 |
|
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.
Pssm-ID: 119321 [Multi-domain] Cd Length: 263 Bit Score: 253.49 E-value: 9.01e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 53 TSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAAS-MVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATL 131
Cdd:cd06579 1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALlLVNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 132 VMMLLLRGVTRVYTDGSPINTGfsdNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRL 211
Cdd:cd06579 81 GTMFILRGLALLITGGRPISGL---PPLFSFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEAARL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 212 SGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNG 291
Cdd:cd06579 158 SGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVLNNG 237
|
250 260
....*....|....*....|....*.
gi 757599168 292 LNLLGISSNYQMIVKAVVILLAVLVD 317
Cdd:cd06579 238 LNLLGVSSFWQQIVKGAILLLAVALD 263
|
|
| GguB |
NF040906 |
sugar ABC transporter permease; |
49-320 |
9.52e-54 |
|
sugar ABC transporter permease;
Pssm-ID: 468841 [Multi-domain] Cd Length: 375 Bit Score: 179.96 E-value: 9.52e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAA-SMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAF 127
Cdd:NF040906 35 LILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGAVAAvLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAYVGIPAF 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSP----------INTGFSDnaDLFGWFGI---------------------GR-------- 168
Cdd:NF040906 115 IVTLAGMLVFRGLTLVVLGGQSigpfpdgfqkISSGFLP--DLFGGTGLhlltlllgvlaaaalvwsqlrGRrrrikygl 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 169 ---PF-------------------------GIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIK 220
Cdd:NF040906 193 evePMalfiaklvliaaailfftyllasyrGLPNVLIILGVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVT 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 221 IIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSN 300
Cdd:NF040906 273 FLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILGIGID 352
|
330 340
....*....|....*....|..
gi 757599168 301 YQMIVKAVVILLAVLVD--NKK 320
Cdd:NF040906 353 WQQVIKGLVLLAAVAFDvyNKR 374
|
|
| BPD_transp_2 |
pfam02653 |
Branched-chain amino acid transport system / permease component; This is a large family mainly ... |
49-314 |
1.89e-23 |
|
Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.
Pssm-ID: 396977 [Multi-domain] Cd Length: 269 Bit Score: 96.94 E-value: 1.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSG-IDLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGAC-TGVIVAKGKVQA 126
Cdd:pfam02653 5 ILTLASIYAIAALGLTLIYGIAGvINLGHGGFMMLGAYVAAMLLNLLGPGLWLALPVGILVGAAVGLlIGILTLRLKINE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 127 FIATLVMMLLLRGVTRVYTDG-SPINTGFSDNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGN 205
Cdd:pfam02653 85 VIITLLLNLAALGLALFLVTGiLGGEGGTSGITGPSGFPGAFLSFAFAFIFLLALLLVLALWLLLYRTKFGRALRAVGEN 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 206 ESATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPM-AGNGYELDAIAAVVLggtslaGGKGRIVGTLIGALI 284
Cdd:pfam02653 165 EEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSnFGVGLGLDAIAAVVL------GGAGSPIGVVIGSLI 238
|
250 260 270
....*....|....*....|....*....|.
gi 757599168 285 LGFLNN-GLNLLGISSNYQMIVKAVVILLAV 314
Cdd:pfam02653 239 IGLVQSlGLGALGSPPELSLLVLGALLILVL 269
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rbsC |
PRK09512 |
ribose ABC transporter permease protein; Reviewed |
2-320 |
2.46e-175 |
|
ribose ABC transporter permease protein; Reviewed
Pssm-ID: 181922 [Multi-domain] Cd Length: 320 Bit Score: 488.07 E-value: 2.46e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 2 SSTTASSKRWFSKAWLMEQKSLIALLILIAIVSTLSPNFFTVNNFFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA 81
Cdd:PRK09512 1 TTQTVSGRRYFTKAWLIEQKSLIALLVLIAIVSTLSPNFFTVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 82 LTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLLLRGVTRVYTDGSPINTGFSDNADLF 161
Cdd:PRK09512 81 LTGAVAASIVGIEVNALVAVPAALALGAAIGAVTGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDGSPINTGFTDNADLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 162 GWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEVAR 241
Cdd:PRK09512 161 GWFGIGRPLGIPTPVWIMAIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKVKIIVYALCGLLAALAGIIEVAR 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757599168 242 LSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKAVVILLAVLVDNKK 320
Cdd:PRK09512 241 LSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKK 319
|
|
| AraH |
COG1172 |
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ... |
1-318 |
8.37e-94 |
|
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];
Pssm-ID: 440785 Cd Length: 322 Bit Score: 281.22 E-value: 8.37e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 1 MSSTTASSKRWFSKaWLMEQKSLIALLILIAIVSTLSPNFFTVNNFFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLL 80
Cdd:COG1172 1 MSATTTTARSLLRR-LLPELGLLLALVLLLVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 81 ALTGAVAAS-MVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLLLRGVTRVYTDGSPIntgfSDNAD 159
Cdd:COG1172 80 ALSGVVAALlLVALGLPILLAILLALLVGALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPI----SGLPD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 160 LFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEV 239
Cdd:COG1172 156 AFRALGQGSLLGIPVPVLIALVVALVAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLA 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 757599168 240 ARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKAVVILLAVLVDN 318
Cdd:COG1172 236 ARLGSAQPNAGSGYELDAIAAVVIGGTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDR 314
|
|
| TM_PBP1_transp_AraH_like |
cd06579 |
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ... |
53-317 |
9.01e-84 |
|
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.
Pssm-ID: 119321 [Multi-domain] Cd Length: 263 Bit Score: 253.49 E-value: 9.01e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 53 TSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAAS-MVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATL 131
Cdd:cd06579 1 AAVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALlLVNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 132 VMMLLLRGVTRVYTDGSPINTGfsdNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRL 211
Cdd:cd06579 81 GTMFILRGLALLITGGRPISGL---PPLFSFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEAARL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 212 SGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNG 291
Cdd:cd06579 158 SGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVLNNG 237
|
250 260
....*....|....*....|....*.
gi 757599168 292 LNLLGISSNYQMIVKAVVILLAVLVD 317
Cdd:cd06579 238 LNLLGVSSFWQQIVKGAILLLAVALD 263
|
|
| COG4158 |
COG4158 |
Predicted ABC-type sugar transport system, permease component [General function prediction ... |
49-317 |
1.58e-71 |
|
Predicted ABC-type sugar transport system, permease component [General function prediction only];
Pssm-ID: 443324 Cd Length: 334 Bit Score: 224.81 E-value: 1.58e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTgAVAASMVSTDVNALVAVAGALALGAAIG-ACTGVIVAKGKVQAF 127
Cdd:COG4158 59 IARQASINIVLAAGMTFVILTGGIDLSVGSILAAS-AVVAVLVSLLPGLGLLGIPAALLVGLLFgLINGLLIAFLKLPPF 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSPINtgfsdNADL-FGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNE 206
Cdd:COG4158 138 IVTLGSLTALRGAARLLANGTTVF-----NPDLpFAWIGNGYLLGIPWLVVIALAVVLASWFILRRTVLGVHIYAVGGNA 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 207 SATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPM-AGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALIL 285
Cdd:COG4158 213 QAARLTGIKVWRVLLFVYAVSGLLAGLGGVMSAARLYAANGLqLGQGYELDAIAAVILGGTSFVGGIGSIWGTLIGALII 292
|
250 260 270
....*....|....*....|....*....|..
gi 757599168 286 GFLNNGLNLLGISSNYQMIVKAVVILLAVLVD 317
Cdd:COG4158 293 AVLNNGLILLGVSDFWQFIIKGLVIIIAVALD 324
|
|
| XylH |
COG4214 |
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism]; |
49-317 |
7.04e-67 |
|
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];
Pssm-ID: 443360 [Multi-domain] Cd Length: 393 Bit Score: 214.59 E-value: 7.04e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAA-SMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAF 127
Cdd:COG4214 55 LLLQNSYIGILAIGMVLVILLGHIDLSVGSVSGFVGAVAAvLMVNWGLPWWLAILAALLVGALIGAWQGFWVAYVGIPSF 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDG---SPINTGFSDNA-----DLFGWFGIG---------------------------RPF-- 170
Cdd:COG4214 135 IVTLAGMLAFRGLTLLVLGGgtiAPFDPTFQAIGngflpDILGTLSWVlgavavaayvalqlrsrrrrrryglpvEPLwl 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 171 -----------------------GIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALC 227
Cdd:COG4214 215 fvlklallavlilgavyllnsyrGIPIVVLILLVLVVVYTFVLTRTVFGRHIYAVGGNPEAARLSGINVRRVTFSVFVNM 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 228 GLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKA 307
Cdd:COG4214 295 GVLAALAGIVFAARLNSATPSAGTGFELDAIAAAVIGGTSLFGGVGTVYGAVIGALVMGSLNNGMSLLGVDSDWQQIVKG 374
|
330
....*....|
gi 757599168 308 VVILLAVLVD 317
Cdd:COG4214 375 LVLLLAVAFD 384
|
|
| GguB |
NF040906 |
sugar ABC transporter permease; |
49-320 |
9.52e-54 |
|
sugar ABC transporter permease;
Pssm-ID: 468841 [Multi-domain] Cd Length: 375 Bit Score: 179.96 E-value: 9.52e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAA-SMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAF 127
Cdd:NF040906 35 LILQNSYILILAIGMLLVIIAGHIDLSVGSVVAFVGAVAAvLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAYVGIPAF 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSP----------INTGFSDnaDLFGWFGI---------------------GR-------- 168
Cdd:NF040906 115 IVTLAGMLVFRGLTLVVLGGQSigpfpdgfqkISSGFLP--DLFGGTGLhlltlllgvlaaaalvwsqlrGRrrrikygl 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 169 ---PF-------------------------GIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIK 220
Cdd:NF040906 193 evePMalfiaklvliaaailfftyllasyrGLPNVLIILGVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGIKTKRVT 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 221 IIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGISSN 300
Cdd:NF040906 273 FLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSILGIGID 352
|
330 340
....*....|....*....|..
gi 757599168 301 YQMIVKAVVILLAVLVD--NKK 320
Cdd:NF040906 353 WQQVIKGLVLLAAVAFDvyNKR 374
|
|
| araH |
PRK11285 |
L-arabinose transporter permease protein; Provisional |
54-320 |
1.94e-52 |
|
L-arabinose transporter permease protein; Provisional
Pssm-ID: 183076 [Multi-domain] Cd Length: 333 Bit Score: 175.25 E-value: 1.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 54 SVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVM 133
Cdd:PRK11285 64 SMIGMVACTMLFCLASGDFDLSVASVVAFAGVVTAVVINATESLWLGVAAGLLLGAAVGLVNGFVIARLKINALITTLAT 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 134 MLLLRGVTRVYTDGSPIntGFSDNAdlFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSG 213
Cdd:PRK11285 144 MQIVRGLAYIISDGKAV--GISDER--FFALGYANFFGVPAPIWLTVACFVVFGFLLNKTTFGRNTLAIGGNEEAARLAG 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 214 INVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLN 293
Cdd:PRK11285 220 VPVVRTKIIIFVLQGLVSALAGVILASRMTSGQPMTSIGFELIVISACVLGGVSLKGGIAKISGVVAGVLILGTVENAMN 299
|
250 260
....*....|....*....|....*..
gi 757599168 294 LLGISSNYQMIVKAVVILLAVLVDNKK 320
Cdd:PRK11285 300 LLNISPFYQYVVRGLILLAAVLFDRYK 326
|
|
| PRK09699 |
PRK09699 |
D-allose ABC transporter permease; |
49-317 |
1.25e-50 |
|
D-allose ABC transporter permease;
Pssm-ID: 182035 [Multi-domain] Cd Length: 312 Bit Score: 169.95 E-value: 1.25e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVSTDVN-ALVAVAGALALGAAIGACTGVIVAKGKVQAF 127
Cdd:PRK09699 42 IFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGVDpFLAALIGGVLVGGALGAINGCLVNWTGLHPF 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSPInTGFSdnADLFGWFGiGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNES 207
Cdd:PRK09699 122 IITLGTNAIFRGITLVISDANSV-YGFS--FDFVNFFA-ASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKN 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 208 ATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGF 287
Cdd:PRK09699 198 SAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGKGRIFSVVIGGLIIGT 277
|
250 260 270
....*....|....*....|....*....|
gi 757599168 288 LNNGLNLLGISSNYQMIVKAVVILLAVLVD 317
Cdd:PRK09699 278 INNGLNILQVQTYYQLVVMGGLIIAAVALD 307
|
|
| mglC |
PRK09478 |
galactose/methyl galactoside ABC transporter permease MglC; |
49-320 |
1.78e-47 |
|
galactose/methyl galactoside ABC transporter permease MglC;
Pssm-ID: 181892 [Multi-domain] Cd Length: 336 Bit Score: 162.55 E-value: 1.78e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVSTDVNA------------LVAVAGALALGAAIGACTG 116
Cdd:PRK09478 45 ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNAnkvfpelatmpiALVILIVCAIGAVIGLING 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 117 VIVAKGKVQAFIATLVMMLLLRGVTRVYTD---GSPInTGFSDNADLF--GWFGIGrPFGIPTPVWLMIIVFAAAWYMLH 191
Cdd:PRK09478 125 LIIAYLNVTPFIATLGTMIIVYGINSLYYDfvgASPI-SGFDSGFSTFaqGFVALG-SFRLSYITFYALIAVAFVWVLWN 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 192 HTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGG 271
Cdd:PRK09478 203 KTRFGKNIFAIGGNPEAAKVSGVNVPLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGG 282
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 757599168 272 KGRIVGTLIGALILGFLNNGLNLLGISSNYQMIVKAVVILLAVLVDNKK 320
Cdd:PRK09478 283 VGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLK 331
|
|
| TM_PBP1_branched-chain-AA_like |
cd06574 |
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ... |
53-314 |
1.96e-41 |
|
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.
Pssm-ID: 119320 [Multi-domain] Cd Length: 266 Bit Score: 144.73 E-value: 1.96e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 53 TSVNAIMAVGMTLVILTSGI-DLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATL 131
Cdd:cd06574 1 GLIYAILALGVYIVFRILGFpDLTVDGSFPLGAAVAAILIVAGYNPWLALIAAILAGAAAGLVTGFLHTRLKINGLLAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 132 VMMLLLRGVTRVYTDGSPINTGFSDNAD-LFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATR 210
Cdd:cd06574 81 LIMIGLYSINLRIMGGPNIPLGTRDTLLgLLLLFGISGTLSIPVVLLLIVLLVLFLVIWFLRTKLGLAMRATGDNPDMAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 211 LSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAG--GKGRIVGTLIGALILGFL 288
Cdd:cd06574 161 SLGINVDRTRILGLVISNALAALGGALYAQYQGFADVNMGIGTGVIGLAAVIIGGAIVGRrtIKASILGVIIGAILYRIA 240
|
250 260
....*....|....*....|....*.
gi 757599168 289 NNGLNLLGISSNYQMIVKAVVILLAV 314
Cdd:cd06574 241 LALALGSGLIPSDLKLITAGVIVLVL 266
|
|
| PRK11618 |
PRK11618 |
inner membrane ABC transporter permease protein YjfF; Provisional |
58-286 |
3.39e-40 |
|
inner membrane ABC transporter permease protein YjfF; Provisional
Pssm-ID: 183235 [Multi-domain] Cd Length: 317 Bit Score: 142.78 E-value: 3.39e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 58 IMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVST-DVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLL 136
Cdd:PRK11618 47 IVAVGMTFVILSGGIDLSVGSVIAFTGVFLAKLIGDyGWSPLLAFPLVLVMGAAFGAFMGALIHYLKLPAFIVTLAGMFL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 137 LRGV-TRVYTDGSPINTGFSDNADLFGW--FGIGRpfgIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSG 213
Cdd:PRK11618 127 ARGVsFLVSEESIPINHPFYDTLSSLAWklPGGGR---LSAMALIMLAVVAIGIFLAHRTRFGNNVYAIGGNATSANLMG 203
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757599168 214 INVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILG 286
Cdd:PRK11618 204 IPVRRTTIRIYMLSGFLATLAGIVFSLYTSAGYALAAVGVELDAIAAVVIGGTLLTGGVGTVLGTLFGVLIQG 276
|
|
| PRK15432 |
PRK15432 |
autoinducer 2 ABC transporter permease LsrC; Provisional |
49-316 |
9.20e-27 |
|
autoinducer 2 ABC transporter permease LsrC; Provisional
Pssm-ID: 185330 [Multi-domain] Cd Length: 344 Bit Score: 107.51 E-value: 9.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFI 128
Cdd:PRK15432 40 VFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVLVGMLLNAGYSLPVACLATLLLGLLAGFFNGVLVAWLRIPAIV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 129 ATLVMMLLLRGVTRVYTDGSPINTGFSDNADLFG--WFGIGrPFGiptpvWLMIIVFAAAWYMLHHTRLGRYIYALGGNE 206
Cdd:PRK15432 120 ATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSApiLLGIS-PIG-----WLTLILILAMAWLLAKTAFGRSFYATGDNL 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 207 SATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILG 286
Cdd:PRK15432 194 QGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGTIIGAVLGAYFLT 273
|
250 260 270
....*....|....*....|....*....|
gi 757599168 287 FLNNGLNLLGISSNYQMIVKAVViLLAVLV 316
Cdd:PRK15432 274 QIDSVLVLLRIPAWWNDFIAGLV-LLGVLV 302
|
|
| BPD_transp_2 |
pfam02653 |
Branched-chain amino acid transport system / permease component; This is a large family mainly ... |
49-314 |
1.89e-23 |
|
Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.
Pssm-ID: 396977 [Multi-domain] Cd Length: 269 Bit Score: 96.94 E-value: 1.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 49 ILQQTSVNAIMAVGMTLVILTSG-IDLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGAC-TGVIVAKGKVQA 126
Cdd:pfam02653 5 ILTLASIYAIAALGLTLIYGIAGvINLGHGGFMMLGAYVAAMLLNLLGPGLWLALPVGILVGAAVGLlIGILTLRLKINE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 127 FIATLVMMLLLRGVTRVYTDG-SPINTGFSDNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGN 205
Cdd:pfam02653 85 VIITLLLNLAALGLALFLVTGiLGGEGGTSGITGPSGFPGAFLSFAFAFIFLLALLLVLALWLLLYRTKFGRALRAVGEN 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 206 ESATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQPM-AGNGYELDAIAAVVLggtslaGGKGRIVGTLIGALI 284
Cdd:pfam02653 165 EEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSnFGVGLGLDAIAAVVL------GGAGSPIGVVIGSLI 238
|
250 260 270
....*....|....*....|....*....|.
gi 757599168 285 LGFLNN-GLNLLGISSNYQMIVKAVVILLAV 314
Cdd:pfam02653 239 IGLVQSlGLGALGSPPELSLLVLGALLILVL 269
|
|
| PRK15038 |
PRK15038 |
autoinducer 2 ABC transporter permease LsrD; |
58-315 |
5.18e-19 |
|
autoinducer 2 ABC transporter permease LsrD;
Pssm-ID: 184998 Cd Length: 330 Bit Score: 86.04 E-value: 5.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 58 IMAVGMTLVILTSGIDLSVGSLLALTGAVAASMVSTDVNALVAVAGALALGAAIGACTGVIVAKGKVQAFIATLVMMLLL 137
Cdd:PRK15038 47 IVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGLINAGLIIYTGVNPLVITLGTLYLF 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 138 RGVTRVYT--DGSPINTGFSDNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGIN 215
Cdd:PRK15038 127 GGSALLLSgmAGATGYEGIGGFPMAFTDFANLDVLGLPVPLIIFLICLLVFWLLMHRTHAGRNVFLIGQSPRVALYSAIP 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 216 VDRIKIIVYALCGLLAALASVIEVARLSSAQPMAGNGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLL 295
Cdd:PRK15038 207 VNRTLCALYAMTGLASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTALAVLLVGYLQQGLQMA 286
|
250 260
....*....|....*....|
gi 757599168 296 GISSNYQMIVKAVVILLAVL 315
Cdd:PRK15038 287 GVPNQISSALSGALLIVVVV 306
|
|
| LivH |
COG0559 |
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ... |
126-316 |
1.77e-13 |
|
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440325 [Multi-domain] Cd Length: 290 Bit Score: 69.32 E-value: 1.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 126 AFIATLVMMLLLRGVTRVY--TDGSPINTGFSDNADLFGwfgigrpFGIPtPVWLMIIVFAAA-----WYMLHHTRLGRY 198
Cdd:COG0559 95 LLLATIGLSLVLQGLVLLIfgADPRSFPALLSGSVELGG-------VSIP-AYRLFIIVVALVllaalWLFLRRTRLGLA 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 199 IYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIeVARLSSAQPMAGNGYELDAIAAVVLGGTslaggkGRIVGT 278
Cdd:COG0559 167 MRAVAQNREAARLMGINVDRVIALTFALGAALAGLAGVL-LAPIYSVSPTMGFLLGLKAFAAVVLGGL------GSIPGA 239
|
170 180 190
....*....|....*....|....*....|....*...
gi 757599168 279 LIGALILGFLNNGLNLLgISSNYQMIVkAVVILLAVLV 316
Cdd:COG0559 240 VVGGLLLGLAESLGAAY-LPSGYKDVV-AFVLLILVLL 275
|
|
| TM_PBP1_LivH_like |
cd06582 |
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ... |
124-316 |
4.71e-13 |
|
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.
Pssm-ID: 119324 [Multi-domain] Cd Length: 272 Bit Score: 67.84 E-value: 4.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 124 VQAFIATLVMMLLLRGVTRVYTdGSPINTGFSDNADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALG 203
Cdd:cd06582 83 LTLLITFGGLLILLQGLLLIFG-GDPRVPPPPLLSGSVELGGVTIPPYRLFIIAVALVLLAALYLFLRRTRLGRAIRAVA 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 204 GNESATRLSGINVDRIKIIVYALCGLLAALASVIeVARLSSAQPMAGNGYELDAIAAVVLGGTslaggkGRIVGTLIGAL 283
Cdd:cd06582 162 QNPEAARLLGINVRRVFALTFALGAALAGLAGVL-LAPITGVSPTMGLLLLLKAFAAVVLGGL------GSIPGAVVGGL 234
|
170 180 190
....*....|....*....|....*....|...
gi 757599168 284 ILGFLNNGLNLLgISSNYQMIVkAVVILLAVLV 316
Cdd:cd06582 235 LLGLAESLAAAY-LSSGYKDAV-AFVLLILVLL 265
|
|
| TM_PBP1_LivM_like |
cd06581 |
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ... |
128-316 |
1.08e-08 |
|
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.
Pssm-ID: 119323 [Multi-domain] Cd Length: 268 Bit Score: 55.14 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSPINTGFSD-NADLFGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNE 206
Cdd:cd06581 79 IATLAFAEIVRLLALNWSSLTGGSNGLSGiPPPLLGGLLLSSPLAFYYLVLAVLLLVLLLLRRLVRSPFGRALRAIRENE 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 207 SATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQP-MAGNGYELDAIAAVVLGGTslaggkGRIVGTLIGALIL 285
Cdd:cd06581 159 VAAEALGINVTRYKLLAFALSAALAGLAGALYAHYLGFVSPeSFGFALSIELLLMVVLGGL------GSLLGPVLGAALL 232
|
170 180 190
....*....|....*....|....*....|.
gi 757599168 286 GFLNNGLNLLGisSNYQMIVKAVVILLAVLV 316
Cdd:cd06581 233 VLLPELLRSLG--PGLRLLVFGLLLILVVLF 261
|
|
| LivM |
COG4177 |
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ... |
128-316 |
4.16e-08 |
|
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443336 [Multi-domain] Cd Length: 285 Bit Score: 53.55 E-value: 4.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 128 IATLVMMLLLRGVTRVYTDGSPINTGFSDNADL-FGWFGIGRPFGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNE 206
Cdd:COG4177 89 IATLAFAEIVRLLALNLESLTGGADGLSGIPRPtLFGLDLGSPLAFYYLVLALLVLVLLLLRRLVRSRFGRALRAIRENE 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 207 SATRLSGINVDRIKIIVYALCGLLAALASVIEVARLSSAQP-MAGNGYELDAIAAVVLGGTslaggkGRIVGTLIGALIL 285
Cdd:COG4177 169 IAAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSPeSFSFLLSIEILLMVVLGGL------GSLLGPVLGAVLL 242
|
170 180 190
....*....|....*....|....*....|.
gi 757599168 286 GFLNNGLNLLGissNYQMIVKAVVILLAVLV 316
Cdd:COG4177 243 VLLPELLRSLP---EYRLLIFGLLLILVVLF 270
|
|
| TM_PBP1_transp_TpRbsC_like |
cd06580 |
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ... |
176-313 |
2.32e-07 |
|
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.
Pssm-ID: 119322 [Multi-domain] Cd Length: 234 Bit Score: 50.90 E-value: 2.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 176 VWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIVYALCGLLAALASVIEVARLS---SAQPMAGNG 252
Cdd:cd06580 98 LLLALLLVILVWLLLYRTRFGLRLRAVGENPRAARYAGINVKRVRLLAMLISGALAGLAGAYLVLGVQgrfTEGMSAGYG 177
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757599168 253 YelDAIAAVVLGGtslaggkGRIVGTLIGALILGFLNNGLNLL----GISSNYQMIVKAVVILLA 313
Cdd:cd06580 178 F--IAIAVALLGR-------WNPLGILLAALLFGALEAGGIALqrsgGVPSELVQVLPGIIVLFV 233
|
|
| NupQ |
COG1079 |
ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and ... |
170-316 |
1.56e-05 |
|
ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ [Nucleotide transport and metabolism];
Pssm-ID: 440697 [Multi-domain] Cd Length: 309 Bit Score: 45.83 E-value: 1.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 170 FGIPTPVWLMIIVFAAAWYMLHHTRLGRYIYALGGNESATRLSGINVDRIKIIvyalcgllaalaSVIevarLSSAqpMA 249
Cdd:COG1079 145 FGQSPLVYLALLLVPLVWWVLYRTRFGLRLRAVGENPAAADALGINVYRIRYL------------AVL----IGGA--LA 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599168 250 G-------------------NGYELDAIAAVVLggtslagGKGRIVGTLIGALILGFLNN-GLNLLGISSN-----YQMI 304
Cdd:COG1079 207 GlggaylslgyvgsftegmtAGRGFIALAAVIF-------GRWRPLGALLAALLFGFADAlQLRLQALGIGipsqlLLML 279
|
170
....*....|..
gi 757599168 305 VKAVVILLAVLV 316
Cdd:COG1079 280 PYVLTILVLAGF 291
|
|
| |
