NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|757599166|ref|WP_042846813|]
View 

MULTISPECIES: D-ribose pyranase [Providencia]

Protein Classification

D-ribose pyranase( domain architecture ID 10013879)

D-ribose pyranase catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose, and also catalyzes the conversion between beta-allofuranose and beta-allopyranose.

EC:  5.4.99.62
PubMed:  12738765

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK11797 PRK11797
D-ribose pyranase; Provisional
1-139 3.39e-82

D-ribose pyranase; Provisional


:

Pssm-ID: 183318  Cd Length: 139  Bit Score: 237.43  E-value: 3.39e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:PRK11797   1 MKKTGLLNSEISSVIARLGHTDTLVICDAGLPIPNGVERIDLALTKGVPSFLDVLDVVLSEMQVEKAILAEEIKEHNPEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757599166  81 EDAILAHLQQLEVTQNNTIEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGVTF 139
Cdd:PRK11797  81 HEALLTQLEQLEQHQGNTIEIEYVSHEEFKQLTAESKAVIRTGECTPYANIILESGVTF 139
 
Name Accession Description Interval E-value
PRK11797 PRK11797
D-ribose pyranase; Provisional
1-139 3.39e-82

D-ribose pyranase; Provisional


Pssm-ID: 183318  Cd Length: 139  Bit Score: 237.43  E-value: 3.39e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:PRK11797   1 MKKTGLLNSEISSVIARLGHTDTLVICDAGLPIPNGVERIDLALTKGVPSFLDVLDVVLSEMQVEKAILAEEIKEHNPEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757599166  81 EDAILAHLQQLEVTQNNTIEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGVTF 139
Cdd:PRK11797  81 HEALLTQLEQLEQHQGNTIEIEYVSHEEFKQLTAESKAVIRTGECTPYANIILESGVTF 139
RbsD COG1869
D-ribose pyranose/furanose isomerase RbsD [Carbohydrate transport and metabolism];
1-137 8.92e-75

D-ribose pyranose/furanose isomerase RbsD [Carbohydrate transport and metabolism];


Pssm-ID: 441474  Cd Length: 129  Bit Score: 218.41  E-value: 8.92e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:COG1869    1 MKKTGILNSELSRVLARLGHTDTIVIADAGLPIPPGVERIDLALTPGVPSFLDVLDAVLSELQVEKAILAEEIKEKNPEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757599166  81 EDAILAHLqqlevtqnNTIEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGV 137
Cdd:COG1869   81 HEALLELL--------PGIEIEYVSHEEFKELTKQAKAVIRTGECTPYANIILVSGV 129
RbsD_FucU pfam05025
RbsD / FucU transport protein family; The Escherichia coli high-affinity ribose-transport ...
1-138 3.64e-62

RbsD / FucU transport protein family; The Escherichia coli high-affinity ribose-transport system consists of six proteins encoded by the rbs operon (rbsD, rbsA, rbsC, rbsB, rbsK and rbsR). RbsD was originally thought to be a high affinity ribose transport protein, but further analysis shows that it is a D-ribose pyranase. It catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta-allofuranose and beta-allopyranose. This family also includes FucU a component of the fucose operon and is a L-fucose mutarotase, involved in the anomeric conversion of L-fucose. It also exhibits a pyranase activity for D-ribose. Both have been classified in the RbsD/FucU family of proteins. Members of this family are ubiquitous having been found in organizms from eubacteria to mammals.


Pssm-ID: 428264  Cd Length: 132  Bit Score: 186.46  E-value: 3.64e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166    1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:pfam05025   1 MKKSGILNPELLKVLAEMGHGDEIVIADAGFPIPSGVERIDLALRAGGPSFLDVLDAVLSELPVEKVYVAEEIVEGNPEV 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 757599166   81 EDAILAHLQQLEVtqnntiEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGVT 138
Cdd:pfam05025  81 WAEYLALLPKAEG------EIEYVEHEAFKERAKKAKAVVRTGETTPYANIILKKGVV 132
 
Name Accession Description Interval E-value
PRK11797 PRK11797
D-ribose pyranase; Provisional
1-139 3.39e-82

D-ribose pyranase; Provisional


Pssm-ID: 183318  Cd Length: 139  Bit Score: 237.43  E-value: 3.39e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:PRK11797   1 MKKTGLLNSEISSVIARLGHTDTLVICDAGLPIPNGVERIDLALTKGVPSFLDVLDVVLSEMQVEKAILAEEIKEHNPEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 757599166  81 EDAILAHLQQLEVTQNNTIEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGVTF 139
Cdd:PRK11797  81 HEALLTQLEQLEQHQGNTIEIEYVSHEEFKQLTAESKAVIRTGECTPYANIILESGVTF 139
RbsD COG1869
D-ribose pyranose/furanose isomerase RbsD [Carbohydrate transport and metabolism];
1-137 8.92e-75

D-ribose pyranose/furanose isomerase RbsD [Carbohydrate transport and metabolism];


Pssm-ID: 441474  Cd Length: 129  Bit Score: 218.41  E-value: 8.92e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:COG1869    1 MKKTGILNSELSRVLARLGHTDTIVIADAGLPIPPGVERIDLALTPGVPSFLDVLDAVLSELQVEKAILAEEIKEKNPEL 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 757599166  81 EDAILAHLqqlevtqnNTIEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGV 137
Cdd:COG1869   81 HEALLELL--------PGIEIEYVSHEEFKELTKQAKAVIRTGECTPYANIILVSGV 129
RbsD_FucU pfam05025
RbsD / FucU transport protein family; The Escherichia coli high-affinity ribose-transport ...
1-138 3.64e-62

RbsD / FucU transport protein family; The Escherichia coli high-affinity ribose-transport system consists of six proteins encoded by the rbs operon (rbsD, rbsA, rbsC, rbsB, rbsK and rbsR). RbsD was originally thought to be a high affinity ribose transport protein, but further analysis shows that it is a D-ribose pyranase. It catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta-allofuranose and beta-allopyranose. This family also includes FucU a component of the fucose operon and is a L-fucose mutarotase, involved in the anomeric conversion of L-fucose. It also exhibits a pyranase activity for D-ribose. Both have been classified in the RbsD/FucU family of proteins. Members of this family are ubiquitous having been found in organizms from eubacteria to mammals.


Pssm-ID: 428264  Cd Length: 132  Bit Score: 186.46  E-value: 3.64e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166    1 MKKGVLLNANVTSVIAKLGHTDQITLADAGLPISQGTERIDLAITQGLPDFMSVLSVITQEMQVEKAILAEEISTNNPQM 80
Cdd:pfam05025   1 MKKSGILNPELLKVLAEMGHGDEIVIADAGFPIPSGVERIDLALRAGGPSFLDVLDAVLSELPVEKVYVAEEIVEGNPEV 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 757599166   81 EDAILAHLQQLEVtqnntiEIIYCSHERFKQLTHDSKAVIRTGECSPFANIILCSGVT 138
Cdd:pfam05025  81 WAEYLALLPKAEG------EIEYVEHEAFKERAKKAKAVVRTGETTPYANIILKKGVV 132
FucU COG4154
L-fucose mutarotase/ribose pyranase, RbsD/FucU family [Carbohydrate transport and metabolism];
1-139 8.13e-08

L-fucose mutarotase/ribose pyranase, RbsD/FucU family [Carbohydrate transport and metabolism];


Pssm-ID: 443323  Cd Length: 143  Bit Score: 47.85  E-value: 8.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757599166   1 MKKGV--LLNANVTSVIAKLGHTDQITLADAGLP---ISQGTERID-LAITQGLPdfmSVLSVITQEMQVEKAILAEEIS 74
Cdd:COG4154    1 MLKGIdpLLSPELLKVLAEMGHGDEIVLADANFPaesLARRVVRLDgHSAPELLE---AILSLFPLDTFVDDPVVRMEVV 77
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757599166  75 TNNPQMEDAILAHLQQLEVTQNNTIEIIYCshERFK--QLTHDSKAVIRTGECSPFANIILCSGVTF 139
Cdd:COG4154   78 GGPDEVPPVWAEYQAIIAKAEGRPVPIERL--ERFAfyERAKKAYAVVATGETRLYGNIILKKGVIP 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH