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Conserved domains on  [gi|752540489|ref|WP_041211936|]
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MULTISPECIES: transcriptional regulator [Aeromonas]

Protein Classification

transcriptional regulator( domain architecture ID 11459460)

transcriptional regulator containing a PAS and a DNA-binding helix-turn-helix domain

Gene Ontology:  GO:0003677|GO:0140110

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
14-217 1.78e-80

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


:

Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 239.36  E-value: 1.78e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  14 TDEERHLIASFEPAVAALSALFGPGCEVVLHAFDSLHASVIKIANGHITGRQEGAPVTDFALDKLHSAAGSQ---WSSYF 90
Cdd:COG2964    2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpdvIGNYE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  91 SRTREGSLLKSSSITISNREGKPIGMLCVNF--SLDTPLGSLLDTFAPPAVPPAHGTETFASSVDDLVA----QVIAKVD 164
Cdd:COG2964   82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFdlSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDeiidEALAEVG 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 752540489 165 RDPGLGSSVRNKAIVHRLYDMGIFEIKDAAQLVAELLGISRHTVYLHIRNHKA 217
Cdd:COG2964  162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
14-217 1.78e-80

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 239.36  E-value: 1.78e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  14 TDEERHLIASFEPAVAALSALFGPGCEVVLHAFDSLHASVIKIANGHITGRQEGAPVTDFALDKLHSAAGSQ---WSSYF 90
Cdd:COG2964    2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpdvIGNYE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  91 SRTREGSLLKSSSITISNREGKPIGMLCVNF--SLDTPLGSLLDTFAPPAVPPAHGTETFASSVDDLVA----QVIAKVD 164
Cdd:COG2964   82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFdlSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDeiidEALAEVG 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 752540489 165 RDPGLGSSVRNKAIVHRLYDMGIFEIKDAAQLVAELLGISRHTVYLHIRNHKA 217
Cdd:COG2964  162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
21-127 1.08e-41

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 137.26  E-value: 1.08e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489   21 IASFEPAVAALSALFGPGCEVVLHAFDSLHASVIKIANGHITGRQEGAPVTDFALDKLHSAAGSQ---WSSYFSRTREGS 97
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDPEHSIVAIANGHVTGRKVGDPITDLALELLKQEEYEEkdyLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|
gi 752540489   98 LLKSSSITISNREGKPIGMLCVNFSLDTPL 127
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALL 110
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
14-217 1.78e-80

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 239.36  E-value: 1.78e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  14 TDEERHLIASFEPAVAALSALFGPGCEVVLHAFDSLHASVIKIANGHITGRQEGAPVTDFALDKLHSAAGSQ---WSSYF 90
Cdd:COG2964    2 SKEDKELLESYIPIADGLAALFGPNCEVVLHDLEDPEHSIVAIANGHVSGRKVGDPITDLGLELLKDGAYEDpdvIGNYE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489  91 SRTREGSLLKSSSITISNREGKPIGMLCVNF--SLDTPLGSLLDTFAPPAVPPAHGTETFASSVDDLVA----QVIAKVD 164
Cdd:COG2964   82 TRTKDGRLLKSSTIFIRDEKGKPIGALCINFdlSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDeiidEALAEVG 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 752540489 165 RDPGLGSSVRNKAIVHRLYDMGIFEIKDAAQLVAELLGISRHTVYLHIRNHKA 217
Cdd:COG2964  162 KPPSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
21-127 1.08e-41

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 137.26  E-value: 1.08e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 752540489   21 IASFEPAVAALSALFGPGCEVVLHAFDSLHASVIKIANGHITGRQEGAPVTDFALDKLHSAAGSQ---WSSYFSRTREGS 97
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDPEHSIVAIANGHVTGRKVGDPITDLALELLKQEEYEEkdyLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|
gi 752540489   98 LLKSSSITISNREGKPIGMLCVNFSLDTPL 127
Cdd:pfam08348  81 ILKSSTIFIRDEDGKIIGLLCINFDITALL 110
HTH_22 pfam13309
HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding ...
151-213 1.52e-19

HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding domain.


Pssm-ID: 463841 [Multi-domain]  Cd Length: 63  Bit Score: 78.66  E-value: 1.52e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 752540489  151 SVDDLVAQVIAKVDRDPGLGSSVRNKAIVHRLYDMGIFEIKDAAQLVAELLGISRHTVYLHIR 213
Cdd:pfam13309   1 LLDSIIDEVLADVGKPPARLTKEEKREIVRALDEKGAFLLKGAVEKVAKRLGVSRATVYNYLR 63
HTH_10 pfam04967
HTH DNA binding domain;
174-218 3.16e-03

HTH DNA binding domain;


Pssm-ID: 282780 [Multi-domain]  Cd Length: 53  Bit Score: 34.89  E-value: 3.16e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 752540489  174 RNKAIVHRLYDMGIFEIKDAAQL--VAELLGISRHTVYLHIRnhKAE 218
Cdd:pfam04967   4 RQLEVLRLAYEMGYFDYPRRVTLkeLAKELGISKSTLSEHLR--RAE 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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