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Concise Results
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Full Results
MULTISPECIES: urocanate hydratase [Serratia]
Protein Classification
urocanate hydratase ( domain architecture ID 10012377 )
urocanate hydratase catalyzes the conversion of 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to urocanate in the degradation of L-histidine to glutamate
List of domain hits
Name
Accession
Description
Interval
E-value
PRK05414
PRK05414 urocanate hydratase; Provisional
11-556
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 1218.06
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 11 DV RAPRGT Q L N AK S WL T EA P LRMLMNNLDPEVAE N P H ELVVYGGIGRAAR D W D CYD K IV E TLK T LE E DETLLVQSGKPVG 90
Cdd:PRK05414 11 EI RAPRGT E L T AK G WL Q EA A LRMLMNNLDPEVAE R P E ELVVYGGIGRAAR N W E CYD A IV K TLK E LE D DETLLVQSGKPVG 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 91 VFKTH SN APRVLIANSNLVPHWA T WEHFNEL D AKGL A MYGQMTAGSWIYIGSQGIVQGTYETF V EA G RQH YD G S L Q GR W V 170
Cdd:PRK05414 91 VFKTH PD APRVLIANSNLVPHWA N WEHFNEL E AKGL T MYGQMTAGSWIYIGSQGIVQGTYETF A EA A RQH FG G D L A GR L V 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 171 LTAGLGGMGGAQPLAAT L AGA CS L NI E CQQ SRID F RL K T R Y V DE Q A N DLD D ALA RIKKYTSE G KAI SI A L C GNAA EI LPE 250
Cdd:PRK05414 171 LTAGLGGMGGAQPLAAT M AGA VC L AV E VDE SRID K RL R T G Y L DE K A D DLD E ALA LAEEAKAA G EPL SI G L L GNAA DV LPE 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 251 LVRRG V RPD M VTDQTSAHDPLNGYLP K GW SW EE YRQRAQTE P AKV V A AAK Q SMA D HV K AMLAFQ QM G VPT FDYGNNIRQM 330
Cdd:PRK05414 251 LVRRG I RPD L VTDQTSAHDPLNGYLP V GW TL EE AAELRAED P EEF V K AAK A SMA R HV E AMLAFQ AR G AYV FDYGNNIRQM 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 331 A KET GV D NAFDFPGFVPAYIRPLFC R G I GPFRW A ALSGDP Q DIYKTDA M VKEL I PDDEHLHRW L DMARERI S FQGLPARI 410
Cdd:PRK05414 331 A FDA GV E NAFDFPGFVPAYIRPLFC E G K GPFRW V ALSGDP E DIYKTDA A VKEL F PDDEHLHRW I DMARERI L FQGLPARI 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 411 CW V G L G Q RA K LGLAFNEMVR R GEL S APIVIGRDHLDSGSV S SPNRETEAMKDGSDAV S DWPLLNALLNTASGATWVSLHH 490
Cdd:PRK05414 411 CW L G Y G E RA R LGLAFNEMVR N GEL K APIVIGRDHLDSGSV A SPNRETEAMKDGSDAV A DWPLLNALLNTASGATWVSLHH 490
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751564404 491 GGGVGMG F S Q H S G M VIV C DGT D EAAER IA RVL H NDPATGVMRHADAGY D IAI DC A R E Q G LN LPM V A 556
Cdd:PRK05414 491 GGGVGMG Y S I H A G F VIV A DGT E EAAER LE RVL T NDPATGVMRHADAGY E IAI ET A K E K G IT LPM L A 556
Name
Accession
Description
Interval
E-value
PRK05414
PRK05414 urocanate hydratase; Provisional
11-556
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 1218.06
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 11 DV RAPRGT Q L N AK S WL T EA P LRMLMNNLDPEVAE N P H ELVVYGGIGRAAR D W D CYD K IV E TLK T LE E DETLLVQSGKPVG 90
Cdd:PRK05414 11 EI RAPRGT E L T AK G WL Q EA A LRMLMNNLDPEVAE R P E ELVVYGGIGRAAR N W E CYD A IV K TLK E LE D DETLLVQSGKPVG 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 91 VFKTH SN APRVLIANSNLVPHWA T WEHFNEL D AKGL A MYGQMTAGSWIYIGSQGIVQGTYETF V EA G RQH YD G S L Q GR W V 170
Cdd:PRK05414 91 VFKTH PD APRVLIANSNLVPHWA N WEHFNEL E AKGL T MYGQMTAGSWIYIGSQGIVQGTYETF A EA A RQH FG G D L A GR L V 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 171 LTAGLGGMGGAQPLAAT L AGA CS L NI E CQQ SRID F RL K T R Y V DE Q A N DLD D ALA RIKKYTSE G KAI SI A L C GNAA EI LPE 250
Cdd:PRK05414 171 LTAGLGGMGGAQPLAAT M AGA VC L AV E VDE SRID K RL R T G Y L DE K A D DLD E ALA LAEEAKAA G EPL SI G L L GNAA DV LPE 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 251 LVRRG V RPD M VTDQTSAHDPLNGYLP K GW SW EE YRQRAQTE P AKV V A AAK Q SMA D HV K AMLAFQ QM G VPT FDYGNNIRQM 330
Cdd:PRK05414 251 LVRRG I RPD L VTDQTSAHDPLNGYLP V GW TL EE AAELRAED P EEF V K AAK A SMA R HV E AMLAFQ AR G AYV FDYGNNIRQM 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 331 A KET GV D NAFDFPGFVPAYIRPLFC R G I GPFRW A ALSGDP Q DIYKTDA M VKEL I PDDEHLHRW L DMARERI S FQGLPARI 410
Cdd:PRK05414 331 A FDA GV E NAFDFPGFVPAYIRPLFC E G K GPFRW V ALSGDP E DIYKTDA A VKEL F PDDEHLHRW I DMARERI L FQGLPARI 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 411 CW V G L G Q RA K LGLAFNEMVR R GEL S APIVIGRDHLDSGSV S SPNRETEAMKDGSDAV S DWPLLNALLNTASGATWVSLHH 490
Cdd:PRK05414 411 CW L G Y G E RA R LGLAFNEMVR N GEL K APIVIGRDHLDSGSV A SPNRETEAMKDGSDAV A DWPLLNALLNTASGATWVSLHH 490
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751564404 491 GGGVGMG F S Q H S G M VIV C DGT D EAAER IA RVL H NDPATGVMRHADAGY D IAI DC A R E Q G LN LPM V A 556
Cdd:PRK05414 491 GGGVGMG Y S I H A G F VIV A DGT E EAAER LE RVL T NDPATGVMRHADAGY E IAI ET A K E K G IT LPM L A 556
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
11-556
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 1149.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 11 DV RAP R GT Q L N AK S W LT EA P LRMLMNNLDPEVAE N P H ELVVYGG I GRAAR D W DC YD K IV ET LK T LE E DETLLVQSGKPVG 90
Cdd:COG2987 17 EI RAP P GT E L P AK G W QQ EA A LRMLMNNLDPEVAE H P E ELVVYGG T GRAAR N W AQ YD L IV KY LK E LE D DETLLVQSGKPVG 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 91 VF K TH SN APRVLIANSNLVP H WA T WE H F N EL D A K GL A MYGQMTAGSWIYIG S QGIVQGTYETF VE A G R Q H YD G S L Q G RWV 170
Cdd:COG2987 97 VF R TH PD APRVLIANSNLVP N WA N WE D F E EL E A L GL T MYGQMTAGSWIYIG P QGIVQGTYETF AN A A R K H FG G D L A G KLF 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 171 LTAGLGGMGGAQPLAAT L AG ACS L NI E CQQ SRI DF RL KTR Y V DE Q A N DLD D ALAR I K KYTSEGKAI SI A L C GNAA EI LPE 250
Cdd:COG2987 177 LTAGLGGMGGAQPLAAT M AG GVG L IA E VDP SRI EK RL EQG Y L DE V A D DLD E ALAR A K EAKAKKEPL SI G L L GNAA DV LPE 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 251 LVRRG VR PD M VTDQTSAHDPLNGYLP K G W S W EE YRQRAQTE P AKVVAAA K Q SMA D HV K AML A FQ QM G VPT FDYGNNIRQ M 330
Cdd:COG2987 257 LVRRG IV PD L VTDQTSAHDPLNGYLP A G L S F EE ANELRAED P EEFKELV K E SMA R HV E AML E FQ AR G AYF FDYGNNIRQ E 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 331 A KET GV DN AFDFPGFVPAYIRPLFC R G I GPFRW A ALSGDP Q DIYKTD AMVK EL I P D D EH LHRW LD MARE RIS FQGLPARI 410
Cdd:COG2987 337 A YDA GV KD AFDFPGFVPAYIRPLFC Y G K GPFRW V ALSGDP E DIYKTD EAAL EL F P Q D RD LHRW IR MARE NVL FQGLPARI 416
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 411 CW V G L G Q RAK LG LAFNEMVR R GEL S APIVIGRDHLD S GSV S SPNRETE A MKDGSDAV S DWPLLNAL L NTA S GATWVSLHH 490
Cdd:COG2987 417 CW L G Y G E RAK IA LAFNEMVR K GEL K APIVIGRDHLD V GSV A SPNRETE N MKDGSDAV A DWPLLNAL G NTA R GATWVSLHH 496
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751564404 491 GGGVG M G F S Q H S G M VIV C DG TD EA A ER IA RVL H NDP AT GV M RHADAGY DI AI DC A R E Q G LN LPM VA 556
Cdd:COG2987 497 GGGVG I G Y S I H A G F VIV A DG SE EA D ER LK RVL T NDP GM GV A RHADAGY EE AI ET A K E R G VT LPM LV 562
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
10-554
0e+00
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 1072.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 10 VDV RAPRGT Q L NA K S WL T EA P LRMLMNNLDPEVAE N P HE LVVYGGIG R AAR D W DCY DKIVETLK T LE E DETLLVQSGKPV 89
Cdd:TIGR01228 1 REI RAPRGT K L EC K G WL Q EA A LRMLMNNLDPEVAE D P EN LVVYGGIG K AAR N W EAF DKIVETLK R LE N DETLLVQSGKPV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 90 GVFKTH S NAPRVLIANSNLVPHWA T WEHF N EL D AKGL A MYGQMTAGSWIYIG S QGI V QGTYETF V E AG RQH YD GSL Q G R W 169
Cdd:TIGR01228 81 GVFKTH E NAPRVLIANSNLVPHWA D WEHF H EL E AKGL M MYGQMTAGSWIYIG T QGI L QGTYETF A E LA RQH FG GSL K G K W 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 170 VLTAGLGGMGGAQPLA A T LA G AC S LNI E CQQ SRID F RL K T R Y V DEQ AND LD D ALAR IKKYTS EGK A ISI A L C GNAAE I LP 249
Cdd:TIGR01228 161 VLTAGLGGMGGAQPLA V T MN G GV S IAV E VDE SRID K RL E T K Y C DEQ TDS LD E ALAR AEEAKA EGK P ISI G L L GNAAE V LP 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 250 EL VR RGV R PD M VTDQTSAHDPLNGY L P K G WSW E EYRQRA Q T EP AKV V A AAKQSMA D HV K AMLAFQ QM G VP TFDYGNNIRQ 329
Cdd:TIGR01228 241 EL LK RGV V PD V VTDQTSAHDPLNGY I P E G YTV E DADKLR Q E EP EAY V K AAKQSMA K HV R AMLAFQ KQ G SV TFDYGNNIRQ 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 330 M AKE T GV DN AFDFPGFVPAYIRPLFCRG I GPFRW A ALSGDP Q DIY K TDA M VKEL I P D D E HLHRW L DMA R ER I SFQGLPAR 409
Cdd:TIGR01228 321 V AKE E GV ED AFDFPGFVPAYIRPLFCRG K GPFRW V ALSGDP A DIY R TDA A VKEL F P E D A HLHRW I DMA Q ER V SFQGLPAR 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 410 ICW V G L G Q RAKLGLA F NEMVR R GEL S AP I VIGRDHLD S GSV S SPNRETEAMKDGSDAVSDWPLLNALLNTA S GATWVS L H 489
Cdd:TIGR01228 401 ICW L G Y G E RAKLGLA I NEMVR S GEL K AP V VIGRDHLD A GSV A SPNRETEAMKDGSDAVSDWPLLNALLNTA A GATWVS F H 480
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 751564404 490 HGGGVGMGFS Q H S GMVIV C DGTDEAAERIARVL H NDP AT GV M RHADAGY D IAID C A R EQG LNL PM 554
Cdd:TIGR01228 481 HGGGVGMGFS L H A GMVIV A DGTDEAAERIARVL T NDP GM GV I RHADAGY E IAID V A K EQG IDV PM 545
Urocanase_C
pfam17392 Urocanase C-terminal domain;
352-547
9.06e-136
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 392.24
E-value: 9.06e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 352 PLFC R G I GPFRW A ALSGDP Q DIY K TD AMVK EL I P D DE H L H RW LDM ARE RIS FQGLPARIC WV G L G Q RAK LG LAFNE M VR R 431
Cdd:pfam17392 1 PLFC E G F GPFRW V ALSGDP E DIY R TD EAAL EL F P Q DE D L I RW IKL ARE NVL FQGLPARIC YL G Y G E RAK IA LAFNE L VR E 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 432 GE L SAPIVIGRDHLD S GSV S SP N RETE A MKDGSDA VS DWPLLNAL L N T A S GATWVSLH H GGGVG M G F S Q H S G MVI V C DGT 511
Cdd:pfam17392 81 GE I SAPIVIGRDHLD V GSV A SP F RETE N MKDGSDA IA DWPLLNAL G N A A R GATWVSLH N GGGVG I G Y S I H A G FGM V A DGT 160
170 180 190
....*....|....*....|....*....|....*.
gi 751564404 512 D EA A ER IA RVL HN DP AT GV M RHADAGY DI AID C AR E 547
Cdd:pfam17392 161 E EA D ER LR RVL TW DP GN GV A RHADAGY EE AID V AR R 196
Name
Accession
Description
Interval
E-value
PRK05414
PRK05414 urocanate hydratase; Provisional
11-556
0e+00
urocanate hydratase; Provisional
Pssm-ID: 235448 [Multi-domain]
Cd Length: 556
Bit Score: 1218.06
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 11 DV RAPRGT Q L N AK S WL T EA P LRMLMNNLDPEVAE N P H ELVVYGGIGRAAR D W D CYD K IV E TLK T LE E DETLLVQSGKPVG 90
Cdd:PRK05414 11 EI RAPRGT E L T AK G WL Q EA A LRMLMNNLDPEVAE R P E ELVVYGGIGRAAR N W E CYD A IV K TLK E LE D DETLLVQSGKPVG 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 91 VFKTH SN APRVLIANSNLVPHWA T WEHFNEL D AKGL A MYGQMTAGSWIYIGSQGIVQGTYETF V EA G RQH YD G S L Q GR W V 170
Cdd:PRK05414 91 VFKTH PD APRVLIANSNLVPHWA N WEHFNEL E AKGL T MYGQMTAGSWIYIGSQGIVQGTYETF A EA A RQH FG G D L A GR L V 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 171 LTAGLGGMGGAQPLAAT L AGA CS L NI E CQQ SRID F RL K T R Y V DE Q A N DLD D ALA RIKKYTSE G KAI SI A L C GNAA EI LPE 250
Cdd:PRK05414 171 LTAGLGGMGGAQPLAAT M AGA VC L AV E VDE SRID K RL R T G Y L DE K A D DLD E ALA LAEEAKAA G EPL SI G L L GNAA DV LPE 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 251 LVRRG V RPD M VTDQTSAHDPLNGYLP K GW SW EE YRQRAQTE P AKV V A AAK Q SMA D HV K AMLAFQ QM G VPT FDYGNNIRQM 330
Cdd:PRK05414 251 LVRRG I RPD L VTDQTSAHDPLNGYLP V GW TL EE AAELRAED P EEF V K AAK A SMA R HV E AMLAFQ AR G AYV FDYGNNIRQM 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 331 A KET GV D NAFDFPGFVPAYIRPLFC R G I GPFRW A ALSGDP Q DIYKTDA M VKEL I PDDEHLHRW L DMARERI S FQGLPARI 410
Cdd:PRK05414 331 A FDA GV E NAFDFPGFVPAYIRPLFC E G K GPFRW V ALSGDP E DIYKTDA A VKEL F PDDEHLHRW I DMARERI L FQGLPARI 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 411 CW V G L G Q RA K LGLAFNEMVR R GEL S APIVIGRDHLDSGSV S SPNRETEAMKDGSDAV S DWPLLNALLNTASGATWVSLHH 490
Cdd:PRK05414 411 CW L G Y G E RA R LGLAFNEMVR N GEL K APIVIGRDHLDSGSV A SPNRETEAMKDGSDAV A DWPLLNALLNTASGATWVSLHH 490
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751564404 491 GGGVGMG F S Q H S G M VIV C DGT D EAAER IA RVL H NDPATGVMRHADAGY D IAI DC A R E Q G LN LPM V A 556
Cdd:PRK05414 491 GGGVGMG Y S I H A G F VIV A DGT E EAAER LE RVL T NDPATGVMRHADAGY E IAI ET A K E K G IT LPM L A 556
HutU
COG2987 Urocanate hydratase [Amino acid transport and metabolism];
11-556
0e+00
Urocanate hydratase [Amino acid transport and metabolism];
Pssm-ID: 442226 [Multi-domain]
Cd Length: 567
Bit Score: 1149.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 11 DV RAP R GT Q L N AK S W LT EA P LRMLMNNLDPEVAE N P H ELVVYGG I GRAAR D W DC YD K IV ET LK T LE E DETLLVQSGKPVG 90
Cdd:COG2987 17 EI RAP P GT E L P AK G W QQ EA A LRMLMNNLDPEVAE H P E ELVVYGG T GRAAR N W AQ YD L IV KY LK E LE D DETLLVQSGKPVG 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 91 VF K TH SN APRVLIANSNLVP H WA T WE H F N EL D A K GL A MYGQMTAGSWIYIG S QGIVQGTYETF VE A G R Q H YD G S L Q G RWV 170
Cdd:COG2987 97 VF R TH PD APRVLIANSNLVP N WA N WE D F E EL E A L GL T MYGQMTAGSWIYIG P QGIVQGTYETF AN A A R K H FG G D L A G KLF 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 171 LTAGLGGMGGAQPLAAT L AG ACS L NI E CQQ SRI DF RL KTR Y V DE Q A N DLD D ALAR I K KYTSEGKAI SI A L C GNAA EI LPE 250
Cdd:COG2987 177 LTAGLGGMGGAQPLAAT M AG GVG L IA E VDP SRI EK RL EQG Y L DE V A D DLD E ALAR A K EAKAKKEPL SI G L L GNAA DV LPE 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 251 LVRRG VR PD M VTDQTSAHDPLNGYLP K G W S W EE YRQRAQTE P AKVVAAA K Q SMA D HV K AML A FQ QM G VPT FDYGNNIRQ M 330
Cdd:COG2987 257 LVRRG IV PD L VTDQTSAHDPLNGYLP A G L S F EE ANELRAED P EEFKELV K E SMA R HV E AML E FQ AR G AYF FDYGNNIRQ E 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 331 A KET GV DN AFDFPGFVPAYIRPLFC R G I GPFRW A ALSGDP Q DIYKTD AMVK EL I P D D EH LHRW LD MARE RIS FQGLPARI 410
Cdd:COG2987 337 A YDA GV KD AFDFPGFVPAYIRPLFC Y G K GPFRW V ALSGDP E DIYKTD EAAL EL F P Q D RD LHRW IR MARE NVL FQGLPARI 416
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 411 CW V G L G Q RAK LG LAFNEMVR R GEL S APIVIGRDHLD S GSV S SPNRETE A MKDGSDAV S DWPLLNAL L NTA S GATWVSLHH 490
Cdd:COG2987 417 CW L G Y G E RAK IA LAFNEMVR K GEL K APIVIGRDHLD V GSV A SPNRETE N MKDGSDAV A DWPLLNAL G NTA R GATWVSLHH 496
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 751564404 491 GGGVG M G F S Q H S G M VIV C DG TD EA A ER IA RVL H NDP AT GV M RHADAGY DI AI DC A R E Q G LN LPM VA 556
Cdd:COG2987 497 GGGVG I G Y S I H A G F VIV A DG SE EA D ER LK RVL T NDP GM GV A RHADAGY EE AI ET A K E R G VT LPM LV 562
hutU
TIGR01228 urocanate hydratase; This model represents the second of four enzymes involved in the ...
10-554
0e+00
urocanate hydratase; This model represents the second of four enzymes involved in the degradation of histidine to glutamate. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130295
Cd Length: 545
Bit Score: 1072.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 10 VDV RAPRGT Q L NA K S WL T EA P LRMLMNNLDPEVAE N P HE LVVYGGIG R AAR D W DCY DKIVETLK T LE E DETLLVQSGKPV 89
Cdd:TIGR01228 1 REI RAPRGT K L EC K G WL Q EA A LRMLMNNLDPEVAE D P EN LVVYGGIG K AAR N W EAF DKIVETLK R LE N DETLLVQSGKPV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 90 GVFKTH S NAPRVLIANSNLVPHWA T WEHF N EL D AKGL A MYGQMTAGSWIYIG S QGI V QGTYETF V E AG RQH YD GSL Q G R W 169
Cdd:TIGR01228 81 GVFKTH E NAPRVLIANSNLVPHWA D WEHF H EL E AKGL M MYGQMTAGSWIYIG T QGI L QGTYETF A E LA RQH FG GSL K G K W 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 170 VLTAGLGGMGGAQPLA A T LA G AC S LNI E CQQ SRID F RL K T R Y V DEQ AND LD D ALAR IKKYTS EGK A ISI A L C GNAAE I LP 249
Cdd:TIGR01228 161 VLTAGLGGMGGAQPLA V T MN G GV S IAV E VDE SRID K RL E T K Y C DEQ TDS LD E ALAR AEEAKA EGK P ISI G L L GNAAE V LP 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 250 EL VR RGV R PD M VTDQTSAHDPLNGY L P K G WSW E EYRQRA Q T EP AKV V A AAKQSMA D HV K AMLAFQ QM G VP TFDYGNNIRQ 329
Cdd:TIGR01228 241 EL LK RGV V PD V VTDQTSAHDPLNGY I P E G YTV E DADKLR Q E EP EAY V K AAKQSMA K HV R AMLAFQ KQ G SV TFDYGNNIRQ 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 330 M AKE T GV DN AFDFPGFVPAYIRPLFCRG I GPFRW A ALSGDP Q DIY K TDA M VKEL I P D D E HLHRW L DMA R ER I SFQGLPAR 409
Cdd:TIGR01228 321 V AKE E GV ED AFDFPGFVPAYIRPLFCRG K GPFRW V ALSGDP A DIY R TDA A VKEL F P E D A HLHRW I DMA Q ER V SFQGLPAR 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 410 ICW V G L G Q RAKLGLA F NEMVR R GEL S AP I VIGRDHLD S GSV S SPNRETEAMKDGSDAVSDWPLLNALLNTA S GATWVS L H 489
Cdd:TIGR01228 401 ICW L G Y G E RAKLGLA I NEMVR S GEL K AP V VIGRDHLD A GSV A SPNRETEAMKDGSDAVSDWPLLNALLNTA A GATWVS F H 480
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 751564404 490 HGGGVGMGFS Q H S GMVIV C DGTDEAAERIARVL H NDP AT GV M RHADAGY D IAID C A R EQG LNL PM 554
Cdd:TIGR01228 481 HGGGVGMGFS L H A GMVIV A DGTDEAAERIARVL T NDP GM GV I RHADAGY E IAID V A K EQG IDV PM 545
Urocanase_C
pfam17392 Urocanase C-terminal domain;
352-547
9.06e-136
Urocanase C-terminal domain;
Pssm-ID: 465414 [Multi-domain]
Cd Length: 196
Bit Score: 392.24
E-value: 9.06e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 352 PLFC R G I GPFRW A ALSGDP Q DIY K TD AMVK EL I P D DE H L H RW LDM ARE RIS FQGLPARIC WV G L G Q RAK LG LAFNE M VR R 431
Cdd:pfam17392 1 PLFC E G F GPFRW V ALSGDP E DIY R TD EAAL EL F P Q DE D L I RW IKL ARE NVL FQGLPARIC YL G Y G E RAK IA LAFNE L VR E 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 432 GE L SAPIVIGRDHLD S GSV S SP N RETE A MKDGSDA VS DWPLLNAL L N T A S GATWVSLH H GGGVG M G F S Q H S G MVI V C DGT 511
Cdd:pfam17392 81 GE I SAPIVIGRDHLD V GSV A SP F RETE N MKDGSDA IA DWPLLNAL G N A A R GATWVSLH N GGGVG I G Y S I H A G FGM V A DGT 160
170 180 190
....*....|....*....|....*....|....*.
gi 751564404 512 D EA A ER IA RVL HN DP AT GV M RHADAGY DI AID C AR E 547
Cdd:pfam17392 161 E EA D ER LR RVL TW DP GN GV A RHADAGY EE AID V AR R 196
Urocanase
pfam01175 Urocanase Rossmann-like domain;
141-349
3.66e-130
Urocanase Rossmann-like domain;
Pssm-ID: 460098 [Multi-domain]
Cd Length: 209
Bit Score: 378.68
E-value: 3.66e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 141 G S QGIVQGTYETF VE A G R Q H YD G S L Q G RWVL TAGLGGMGGAQPLAAT L AG ACS L NI E CQQ SRI DF RL KTR Y V DE Q A N DLD 220
Cdd:pfam01175 1 G T QGIVQGTYETF AA A A R K H FG G D L A G KLFV TAGLGGMGGAQPLAAT M AG GVG L VV E VDP SRI EK RL EQG Y L DE V A D DLD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 221 D ALAR I K KYTS E GKAI SI A L C GNAA EI L P ELVRRG VR PD M VTDQTSAHDPLNGY L P K G WSW EE YRQRAQTE P A K VVAAAK 300
Cdd:pfam01175 81 E ALAR A K EAKA E KEPL SI G L L GNAA DV L E ELVRRG II PD L VTDQTSAHDPLNGY I P A G LTF EE ANELRKED P E K YKELVQ 160
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 751564404 301 Q SMA D HV K AMLA F Q QM G VPT FDYGNN I R QM AK ET GVD N AFDFPGFVPAY 349
Cdd:pfam01175 161 E SMA R HV E AMLA L Q AR G AYF FDYGNN F R LE AK DA GVD G AFDFPGFVPAY 209
Urocanase_N
pfam17391 Urocanase N-terminal domain;
12-138
2.04e-90
Urocanase N-terminal domain;
Pssm-ID: 465413 [Multi-domain]
Cd Length: 127
Bit Score: 273.65
E-value: 2.04e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 751564404 12 V RAPRGT Q L NA K S W LT EA P LRMLMNNLDPEVAE N P H ELVVYGG I G R AAR D W DCY D K IV ET LK T LEED E TLLVQSGKPVG V 91
Cdd:pfam17391 1 I RAPRGT E L PC K G W QQ EA A LRMLMNNLDPEVAE Y P E ELVVYGG N G K AAR N W AQF D L IV KY LK E LEED Q TLLVQSGKPVG L 80
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 751564404 92 F K TH SN APRVLIANSNLVP H WATWE H F NE L D A K GL A MYGQMTAGSWI 138
Cdd:pfam17391 81 F R TH PD APRVLIANSNLVP N WATWE D F ER L E A L GL T MYGQMTAGSWI 127
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
