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Conserved domains on  [gi|746356045|ref|WP_039400712|]
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MULTISPECIES: 50S ribosomal protein L7Ae [Halopenitus]

Protein Classification

50S ribosomal protein L7ae( domain architecture ID 10022760)

50S ribosomal protein L7Ae is a multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
eL8_ribo TIGR03677
ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version ...
 4-120 3.20e-56

ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version of the large ribosomal complex protein eL8, previously designated L8 in yeast and L7Ae in the archaea. The family is a narrower version of the pfam01248 model which also recognizes the L30 protein.


:

Pssm-ID: 188367 [Multi-domain]  Cd Length: 117  Bit Score: 170.32  E-value: 3.20e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045    4 YVDYDTPADLADRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDD 83
Cdd:TIGR03677   1 YVKFEVPEELADKALEAVEKARETGKIKKGTNEVTKAVERGIAKLVVIAEDVEPPEIVAHLPALCEEKGIPYIYVKSKED 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 746356045   84 VGHAAGLEVGSAAAAIVDAGEASDDVEDIAGKVEELR 120
Cdd:TIGR03677  81 LGAAAGLEVGAASAAIVDAGKAEELLKEIIEKVEALK 117
 
Name Accession Description Interval E-value
eL8_ribo TIGR03677
ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version ...
 4-120 3.20e-56

ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version of the large ribosomal complex protein eL8, previously designated L8 in yeast and L7Ae in the archaea. The family is a narrower version of the pfam01248 model which also recognizes the L30 protein.


Pssm-ID: 188367 [Multi-domain]  Cd Length: 117  Bit Score: 170.32  E-value: 3.20e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045    4 YVDYDTPADLADRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDD 83
Cdd:TIGR03677   1 YVKFEVPEELADKALEAVEKARETGKIKKGTNEVTKAVERGIAKLVVIAEDVEPPEIVAHLPALCEEKGIPYIYVKSKED 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 746356045   84 VGHAAGLEVGSAAAAIVDAGEASDDVEDIAGKVEELR 120
Cdd:TIGR03677  81 LGAAAGLEVGAASAAIVDAGKAEELLKEIIEKVEALK 117
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 15-112 1.34e-29

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 102.16  E-value: 1.34e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  15 DRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSpEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGlEVGS 94
Cdd:COG1358    1 DKILNLLGLARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDAS-ENTKKKLLDLCEEYGVPVVEVGTKEELGKAIG-KVGR 78

                         90
                 ....*....|....*...
gi 746356045  95 AAAAIVDAGEASDDVEDI 112
Cdd:COG1358   79 AVVAITDEGFAKKLLELL 96
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 15-109 8.80e-26

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 92.27  E-value: 8.80e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045   15 DRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGS 94
Cdd:pfam01248   1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRPV 80

                          90
                  ....*....|....*
gi 746356045   95 AAAAIVDAGEASDDV 109
Cdd:pfam01248  81 SALAIKDEGDSKILV 95
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 10-119 1.53e-20

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 80.06  E-value: 1.53e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  10 PADLADRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAG 89
Cdd:cd21104    9 DAQLTQTILDLVQQAANYKQLKKGANEATKTLNRGIAEFIVMAADAEPLEILLHLPLLCEDKNVPYVFVPSKQALGRACG 88

                         90       100       110
                 ....*....|....*....|....*....|..
gi 746356045  90 L--EVGSAAAAIVDAGEASDDVEDIAGKVEEL 119
Cdd:cd21104   89 VsrPVIACSVTTNEGSQLKSQIQSLKDAIEKL 120
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
33-99 4.93e-11

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 54.40  E-value: 4.93e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 746356045  33 GTNETTKSVERGNAKLAFVAEDVSPEeIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGSAAAAI 99
Cdd:PRK13602  15 GTKQTVKALKRGSVKEVVVAEDADPR-LTEKVEALANEKGVPVSKVDSMKKLGKACGIEVGAAAVAI 80
 
Name Accession Description Interval E-value
eL8_ribo TIGR03677
ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version ...
 4-120 3.20e-56

ribosomal protein eL8, archaeal form; This model specifically identifies the archaeal version of the large ribosomal complex protein eL8, previously designated L8 in yeast and L7Ae in the archaea. The family is a narrower version of the pfam01248 model which also recognizes the L30 protein.


Pssm-ID: 188367 [Multi-domain]  Cd Length: 117  Bit Score: 170.32  E-value: 3.20e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045    4 YVDYDTPADLADRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDD 83
Cdd:TIGR03677   1 YVKFEVPEELADKALEAVEKARETGKIKKGTNEVTKAVERGIAKLVVIAEDVEPPEIVAHLPALCEEKGIPYIYVKSKED 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 746356045   84 VGHAAGLEVGSAAAAIVDAGEASDDVEDIAGKVEELR 120
Cdd:TIGR03677  81 LGAAAGLEVGAASAAIVDAGKAEELLKEIIEKVEALK 117
Rpl7Ae COG1358
Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure ...
 15-112 1.34e-29

Ribosomal protein L7Ae or related RNA K-turn-binding protein [Translation, ribosomal structure and biogenesis]; Ribosomal protein L7Ae or related RNA K-turn-binding protein is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440969 [Multi-domain]  Cd Length: 98  Bit Score: 102.16  E-value: 1.34e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  15 DRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSpEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGlEVGS 94
Cdd:COG1358    1 DKILNLLGLARRAGKLVSGEEQVLKAIRKGKAKLVIIAEDAS-ENTKKKLLDLCEEYGVPVVEVGTKEELGKAIG-KVGR 78

                         90
                 ....*....|....*...
gi 746356045  95 AAAAIVDAGEASDDVEDI 112
Cdd:COG1358   79 AVVAITDEGFAKKLLELL 96
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 15-109 8.80e-26

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 92.27  E-value: 8.80e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045   15 DRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGS 94
Cdd:pfam01248   1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRPV 80

                          90
                  ....*....|....*
gi 746356045   95 AAAAIVDAGEASDDV 109
Cdd:pfam01248  81 SALAIKDEGDSKILV 95
SNU13 cd21104
U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, ...
 10-119 1.53e-20

U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13, also known as NHP2-like protein 1 or U4/U6.U5 tri-snRNP 15.5 kDa protein, is a component of the spliceosome B complex, involved in pre-mRNA splicing. It binds to the 5'-stem-loop of U4 snRNA.


Pssm-ID: 411046  Cd Length: 122  Bit Score: 80.06  E-value: 1.53e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  10 PADLADRALDALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAG 89
Cdd:cd21104    9 DAQLTQTILDLVQQAANYKQLKKGANEATKTLNRGIAEFIVMAADAEPLEILLHLPLLCEDKNVPYVFVPSKQALGRACG 88

                         90       100       110
                 ....*....|....*....|....*....|..
gi 746356045  90 L--EVGSAAAAIVDAGEASDDVEDIAGKVEEL 119
Cdd:cd21104   89 VsrPVIACSVTTNEGSQLKSQIQSLKDAIEKL 120
RPL30E COG1911
Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein ...
 20-105 1.94e-12

Ribosomal protein L30E [Translation, ribosomal structure and biogenesis]; Ribosomal protein L30E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441515 [Multi-domain]  Cd Length: 97  Bit Score: 58.30  E-value: 1.94e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  20 ALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDVsPEEIVMHLPELAEEKGIPV-VFVETQDDVGHAAGLEVGSAAAA 98
Cdd:COG1911    7 ALRDAVKTGKVVLGSKQTIKAIKLGKAKLVILAANC-PPEIREDIEYYAKLSNVPVyVYPGTSVELGALCGKPFRVSALA 85


                 ....*..
gi 746356045  99 IVDAGEA 105
Cdd:COG1911   86 IIDPGES 92
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
33-99 4.93e-11

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 54.40  E-value: 4.93e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 746356045  33 GTNETTKSVERGNAKLAFVAEDVSPEeIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGSAAAAI 99
Cdd:PRK13602  15 GTKQTVKALKRGSVKEVVVAEDADPR-LTEKVEALANEKGVPVSKVDSMKKLGKACGIEVGAAAVAI 80
PRK01018 PRK01018
50S ribosomal protein L30e; Reviewed
 20-104 1.02e-09

50S ribosomal protein L30e; Reviewed


Pssm-ID: 179205 [Multi-domain]  Cd Length: 99  Bit Score: 51.50  E-value: 1.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  20 ALEVARDTGTVKKGTNETTKSVERGNAKLAFVAEDvSPEEIVMHLPELAEEKGIPV-VFVETQDDVGHAAGLEVGSAAAA 98
Cdd:PRK01018   7 ELRVAVDTGKVILGSKRTIKAIKLGKAKLVIVASN-CPKDIKEDIEYYAKLSGIPVyEYEGSSVELGTLCGKPFTVSALA 85


                 ....*.
gi 746356045  99 IVDAGE 104
Cdd:PRK01018  86 IVDPGE 91
PTZ00365 PTZ00365
60S ribosomal protein L7Ae-like; Provisional
 30-110 3.11e-07

60S ribosomal protein L7Ae-like; Provisional


Pssm-ID: 240382  Cd Length: 266  Bit Score: 47.15  E-value: 3.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 746356045  30 VKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEvgSAAAAIVDAGEASDDV 109
Cdd:PTZ00365 133 LKYGLNHVTDLVEYKKAKLVVIAHDVDPIELVCFLPALCRKKEVPYCIIKGKSRLGKLVHQK--TAAVVAIDNVRKEDQA 210


                 .
gi 746356045 110 E 110
Cdd:PTZ00365 211 E 211
PRK13601 PRK13601
putative L7Ae-like ribosomal protein; Provisional
 33-98 3.65e-07

putative L7Ae-like ribosomal protein; Provisional


Pssm-ID: 184173  Cd Length: 82  Bit Score: 44.59  E-value: 3.65e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 746356045  33 GTNETTKSVERGNAKLAFVAEDvSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGSAAAA 98
Cdd:PRK13601  12 GAKQTLKAITNCNVLQVYIAKD-AEEHVTKKIKELCEEKSIKIVYIDTMKELGVMCGIDVGAAAAA 76
PTZ00222 PTZ00222
60S ribosomal protein L7a; Provisional
 29-97 7.94e-07

60S ribosomal protein L7a; Provisional


Pssm-ID: 140249  Cd Length: 263  Bit Score: 45.85  E-value: 7.94e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 746356045  29 TVKKGTNETTKSVERGNAKLAFVAEDVSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGSAAA 97
Cdd:PTZ00222 132 AVVTGLQEVTRAIEKKQARMVVIANNVDPVELVLWMPNLCRANKIPYAIVKDMARLGDAIGRKTATCVA 200
PRK06683 PRK06683
hypothetical protein; Provisional
 33-100 2.31e-03

hypothetical protein; Provisional


Pssm-ID: 136002  Cd Length: 82  Bit Score: 34.67  E-value: 2.31e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 746356045  33 GTNETTKSVERGNAKLAFVAEDvSPEEIVMHLPELAEEKGIPVVFVETQDDVGHAAGLEVGSAAAAIV 100
Cdd:PRK06683  15 GHKRTLEAIKNGIVKEVVIAED-ADMRLTHVIIRTALQHNIPITKVESVRKLGKVAGIQVGASAIGII 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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