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Conserved domains on  [gi|743518664|ref|WP_039036085|]
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MULTISPECIES: GNAT family N-acetyltransferase [Shewanella]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10003213)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 8-117 4.70e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


:

Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 62.70  E-value: 4.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   8 ITVSLAQSPDlIAAACALVDSRDdnahpldhqAFMASRAVIVAQNGvGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGI 87
Cdd:COG1246    1 MTIRPATPDD-VPAILELIRPYA---------LEEEIGEFWVAEED-GEIVGCAALHPLDEDLAELRSLAVHPDYRGRGI 69

                         90       100       110
                 ....*....|....*....|....*....|
gi 743518664  88 AAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:COG1246   70 GRRLLEALLAEARELGLKRLFLLTTSAAIH 99
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 8-117 4.70e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 62.70  E-value: 4.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   8 ITVSLAQSPDlIAAACALVDSRDdnahpldhqAFMASRAVIVAQNGvGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGI 87
Cdd:COG1246    1 MTIRPATPDD-VPAILELIRPYA---------LEEEIGEFWVAEED-GEIVGCAALHPLDEDLAELRSLAVHPDYRGRGI 69

                         90       100       110
                 ....*....|....*....|....*....|
gi 743518664  88 AAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:COG1246   70 GRRLLEALLAEARELGLKRLFLLTTSAAIH 99
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 19-127 5.71e-13

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 61.76  E-value: 5.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   19 IAAACALVDSRDDNAHPLDHQAFMASRAVIVAQNGvGELVGCAVIKA--GCGDIAELGYLMVRPDYRRRGIAAALTQKRI 96
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEED-GELVGFASLSIidDEPPVGEIEGLAVAPEYRGKGIGTALLQALL 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 743518664   97 QIAREMGIRLLFATVREENRASRDNLLKSGM 127
Cdd:pfam00583  86 EWARERGCERIFLEVAADNLAAIALYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 47-110 1.30e-09

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 51.89  E-value: 1.30e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743518664  47 VIVAQNGvGELVGCAVIK--AGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFAT 110
Cdd:cd04301    1 FLVAEDD-GEIVGFASLSpdGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
PRK07922 PRK07922
amino-acid N-acetyltransferase;
49-108 5.83e-07

amino-acid N-acetyltransferase;


Pssm-ID: 236132 [Multi-domain]  Cd Length: 169  Bit Score: 46.84  E-value: 5.83e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  49 VAQNGVGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLF 108
Cdd:PRK07922  49 VAEHLDGEVVGCGALHVMWEDLAEIRTVAVDPAARGRGVGHAIVERLLDVARELGLSRVF 108
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 69-128 1.23e-04

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 40.00  E-value: 1.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   69 DIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRASRDNLLKSGMQ 128
Cdd:TIGR01575  53 DEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFLEVRVSNIAAQALYKKLGFN 112
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 8-117 4.70e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 62.70  E-value: 4.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   8 ITVSLAQSPDlIAAACALVDSRDdnahpldhqAFMASRAVIVAQNGvGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGI 87
Cdd:COG1246    1 MTIRPATPDD-VPAILELIRPYA---------LEEEIGEFWVAEED-GEIVGCAALHPLDEDLAELRSLAVHPDYRGRGI 69

                         90       100       110
                 ....*....|....*....|....*....|
gi 743518664  88 AAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:COG1246   70 GRRLLEALLAEARELGLKRLFLLTTSAAIH 99
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 19-127 5.71e-13

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 61.76  E-value: 5.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   19 IAAACALVDSRDDNAHPLDHQAFMASRAVIVAQNGvGELVGCAVIKA--GCGDIAELGYLMVRPDYRRRGIAAALTQKRI 96
Cdd:pfam00583   7 LLSEEFPEPWPDEPLDLLEDWDEDASEGFFVAEED-GELVGFASLSIidDEPPVGEIEGLAVAPEYRGKGIGTALLQALL 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 743518664   97 QIAREMGIRLLFATVREENRASRDNLLKSGM 127
Cdd:pfam00583  86 EWARERGCERIFLEVAADNLAAIALYEKLGF 116
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
56-137 1.61e-11

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 57.23  E-value: 1.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  56 ELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRASRDNLLKSGMQFWGNYLS 135
Cdd:COG3393    1 ELVAMAGVRAESPGVAEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFRPVGEYAT 80


                 ..
gi 743518664 136 IR 137
Cdd:COG3393   81 VL 82
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
43-119 5.72e-11

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 57.70  E-value: 5.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  43 ASRAVIVAQNGvGELVGCAVI-----KAGCGDIAELGyLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:COG1247   50 PGRPVLVAEED-GEVVGFASLgpfrpRPAYRGTAEES-IYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEA 127


                 ..
gi 743518664 118 SR 119
Cdd:COG1247  128 SI 129
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 68-119 1.96e-10

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 54.66  E-value: 1.96e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 743518664  68 GDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRASR 119
Cdd:COG0456   11 GDEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAI 62
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
15-117 3.79e-10

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 55.09  E-value: 3.79e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  15 SPDLIAAACALVD---SRDDNAHPLDH-QAFMASRAVIVAQNGvGELVGCA----VIKAGCGDIAELGYLMVRPDYRRRG 86
Cdd:COG3153    5 TPEDAEAIAALLRaafGPGREAELVDRlREDPAAGLSLVAEDD-GEIVGHValspVDIDGEGPALLLGPLAVDPEYRGQG 83

                         90       100       110
                 ....*....|....*....|....*....|.
gi 743518664  87 IAAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:COG3153   84 IGRALMRAALEAARERGARAVVLLGDPSLLP 114
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 55-134 5.87e-10

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 54.29  E-value: 5.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  55 GELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRASRDNLLKSG---MQFWG 131
Cdd:COG0454   43 GEPIGFAGLRRLDDKVLELKRLYVLPEYRGKGIGKALLEALLEWARERGCTALELDTLDGNPAAIRFYERLGfkeIERYV 122


                 ...
gi 743518664 132 NYL 134
Cdd:COG0454  123 AYV 125
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 47-110 1.30e-09

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 51.89  E-value: 1.30e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 743518664  47 VIVAQNGvGELVGCAVIK--AGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFAT 110
Cdd:cd04301    1 FLVAEDD-GEIVGFASLSpdGSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 55-152 4.88e-09

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 52.69  E-value: 4.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  55 GELVGCAVIKA--GCGDIAELGYlMVRPDYRRRGIAAALTQKRIQIA-REMGIRLLFATVREENRASRDNLLKSGMQFWG 131
Cdd:COG1670   71 GELIGVVGLYDidRANRSAEIGY-WLAPAYWGKGYATEALRALLDYAfEELGLHRVEAEVDPDNTASIRVLEKLGFRLEG 149

                         90       100
                 ....*....|....*....|....
gi 743518664 132 ---NYLSIRGTGNTVGWYFLVLDD 152
Cdd:COG1670  150 tlrDALVIDGRYRDHVLYSLLREE 173
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 47-117 6.67e-08

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 47.83  E-value: 6.67e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743518664   47 VIVAQNGvGELVGCAVIKAGCGDIAELG-YLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:pfam13508   5 FFVAEDD-GKIVGFAALLPLDDEGALAElRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAA 75
PRK07922 PRK07922
amino-acid N-acetyltransferase;
49-108 5.83e-07

amino-acid N-acetyltransferase;


Pssm-ID: 236132 [Multi-domain]  Cd Length: 169  Bit Score: 46.84  E-value: 5.83e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  49 VAQNGVGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLF 108
Cdd:PRK07922  49 VAEHLDGEVVGCGALHVMWEDLAEIRTVAVDPAARGRGVGHAIVERLLDVARELGLSRVF 108
COG3981 COG3981
Predicted acetyltransferase [General function prediction only];
68-119 1.68e-06

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443180  Cd Length: 170  Bit Score: 45.67  E-value: 1.68e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 743518664  68 GDIaelGYlMVRPDYRRRGIAAALTQKRIQIAREMGI-RLLFaTVREENRASR 119
Cdd:COG3981   93 GHI---GY-GVRPSERGKGYATEMLRLALEEARELGLdRVLI-TCDKDNIASR 140
PRK07757 PRK07757
N-acetyltransferase;
45-109 2.42e-06

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 44.80  E-value: 2.42e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 743518664  45 RAVIVAQNGvGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFA 109
Cdd:PRK07757  41 RDFYVAEEE-GEIVGCCALHILWEDLAEIRSLAVSEDYRGQGIGRMLVEACLEEARELGVKRVFA 104
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
26-107 3.40e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 44.02  E-value: 3.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664  26 VDSRDDNAHpldHqafmasravIVAQNGvGELVGCAVIKAGCGDIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIR 105
Cdd:COG2153   27 LDGKDEDAR---H---------LLAYDD-GELVATARLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERGAR 93


                 ..
gi 743518664 106 LL 107
Cdd:COG2153   94 RI 95
NodA pfam02474
Nodulation protein A (NodA); Rhizobia nodulation (nod) genes control the biosynthesis of Nod ...
 63-145 2.20e-05

Nodulation protein A (NodA); Rhizobia nodulation (nod) genes control the biosynthesis of Nod factors required for infection and nodulation of their legume hosts. Nodulation protein A (NodA) is a N-acetyltransferase involved in production of Nod factors that stimulate mitosis in various plant protoplasts.


Pssm-ID: 426792  Cd Length: 195  Bit Score: 42.85  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   63 IKAGCGDI--AELGYLMVRPDYRRRGIAAALTQKrIQIAREMGIRLLFATVREENRASRDNLLKSGMQFWGNYLSIRGTG 140
Cdd:pfam02474  75 IKVGGVDLlvAELGLYAVRPDLEGLGIGHSILVM-TPVLKELGVPFGFGTVRHALRKHVERLCRNGLATIVSGVRVRSTL 153


                  ....*
gi 743518664  141 NTVGW 145
Cdd:pfam02474 154 PDVYP 158
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 71-128 1.08e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 40.02  E-value: 1.08e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 743518664   71 AELGYlMVRPDYRRRGIA----AALTQkriQIAREMGIRLLFATVREENRASRDNLLKSGMQ 128
Cdd:pfam13302  82 AELGY-WLGPDYWGKGYAteavRALLE---YAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
rimI TIGR01575
ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related ...
 69-128 1.23e-04

ribosomal-protein-alanine acetyltransferase; Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273701 [Multi-domain]  Cd Length: 131  Bit Score: 40.00  E-value: 1.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   69 DIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRASRDNLLKSGMQ 128
Cdd:TIGR01575  53 DEAHILNIAVKPEYQGQGIGRALLRELIDEAKGRGVNEIFLEVRVSNIAAQALYKKLGFN 112
PRK05279 PRK05279
N-acetylglutamate synthase; Validated
 69-109 7.71e-04

N-acetylglutamate synthase; Validated


Pssm-ID: 235386 [Multi-domain]  Cd Length: 441  Bit Score: 38.98  E-value: 7.71e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 743518664  69 DIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFA 109
Cdd:PRK05279 358 KMGEMACLAVHPDYRGSGRGERLLKRIEQRARQLGLKRLFV 398
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 73-108 8.82e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 37.55  E-value: 8.82e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 743518664   73 LGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLF 108
Cdd:pfam13527  73 ITGVATYPEYRGRGVMSRLLRRSLEEMRERGVPLSF 108
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
 69-119 1.53e-03

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 36.15  E-value: 1.53e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 743518664   69 DIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRlLFATVREENRASR 119
Cdd:pfam08445  20 PGGELGALQTLPEHRRRGLGSRLVAALARGIAERGIT-PFAVVVAGNTPSR 69
PRK00756 PRK00756
acyltransferase NodA; Provisional
 63-127 1.73e-03

acyltransferase NodA; Provisional


Pssm-ID: 179111  Cd Length: 196  Bit Score: 37.38  E-value: 1.73e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 743518664  63 IKAGCGDI--AELGYLMVRPDYRRRGIAAAlTQKRIQIAREMGIRLLFATVREENRASRDNLLKSGM 127
Cdd:PRK00756  76 IKVGEVDLlvAELGLYGVRPDLEGLGIAHS-IRAMYPVLQELGVPFAFGTVRHALRNHVERLCRNGL 141
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 38-117 1.81e-03

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 36.48  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 743518664   38 HQAFMASRAVIVAQNGVGELVGcaVIKAGCGDIAELgyLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:pfam13673  23 RERIDQGEYFFFVAFEGGQIVG--VIALRDRGHISL--LFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELTVNASPYA 98
N-Ac-Glu-synth TIGR01890
amino-acid N-acetyltransferase; This model represents a clade of amino-acid ...
 55-109 2.36e-03

amino-acid N-acetyltransferase; This model represents a clade of amino-acid N-acetyltransferases acting mainly on glutamate in the first step of the "acetylated" ornithine biosynthesis pathway. For this reason it is also called N-acetylglutamate synthase. The enzyme may also act on aspartate. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 273856 [Multi-domain]  Cd Length: 429  Bit Score: 37.47  E-value: 2.36e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 743518664   55 GELVGCAVI----KAGCGDIAelgYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFA 109
Cdd:TIGR01890 331 GNIIGCAALypyaEEDCGEMA---CLAVSPEYQDGGRGERLLAHIEDRARQMGISRLFV 386
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 69-117 3.95e-03

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 36.06  E-value: 3.95e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 743518664  69 DIAELGYLMVRPDYRRRGIAAALTQKRIQIAREMGIRLLFATVREENRA 117
Cdd:PRK09491  62 DEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAA 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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