ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742851398  12 LNKVLSFFSEKDTNLIV------VIIGPSGSGKTLLAKraLIDGlFISPD--EPIAGEKFIQSLS----NKDIIVDDVVL 79
Cdd:cd03299    6 LSKDWKEFKLKNVSLEVergdyfVILGPTGSGKSVLLE--TIAG-FIKPDsgKILLNGKDITNLPpekrDISYVPQNYAL 82

                         90       100
                 ....*....|....*....|....*....
gi 742851398  80 FDMRNVLKyvlhSLASGRKVILTGRPEDE 108
Cdd:cd03299   83 FPHMTVYK----NIAYGLKKRKVDKKEIE 107

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

                          10        20        30
                  ....*....|....*....|....*....|....*
gi 742851398   27 IVVIIGPSGSGKTLLAKraLIDGLFispdEPIAGE 61
Cdd:pfam00005  13 ILALVGPNGAGKSTLLK--LIAGLL----SPTEGT 41

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLFispdEPIAGEkfiqslsnkdIIVDDVVLFDMR 83
Cdd:COG1127   33 ILAIIGGSGSGKSVLLK--LIIGLL----RPDSGE----------ILVDGQDITGLS 73

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

                         10        20
                 ....*....|....*....|
gi 742851398  27 IVVIIGPSGSGKTLLAkRAL 46
Cdd:COG4618  360 VLGVIGPSGSGKSTLA-RLL 378

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 742851398  27 IVVIIGPSGSGK-TLLakRAlIDGLfispDEPIAGekfiqslsnkDIIVDDVVLFD 81
Cdd:cd03262   28 VVVIIGPSGSGKsTLL--RC-INLL----EEPDSG----------TIIIDGLKLTD 66

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 742851398  27 IVVIIGPSGSGK-TLLakrALIDGlFISPDepiAGEKFIQ 65
Cdd:COG3840   27 RVAILGPSGAGKsTLL---NLIAG-FLPPD---SGRILWN 59

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLFispdEPIAGEKFIQSlsnKDIIVDDVVlfDMRNVLKYVLHS 92
Cdd:cd03295   29 FLVLIGPSGSGKTTTMK--MINRLI----EPTSGEIFIDG---EDIREQDPV--ELRRKIGYVIQQ 83

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

                         10        20
                 ....*....|....*....|...
gi 742851398  28 VVIIGPSGSGKTLLAKraLIDGL 50
Cdd:cd03246   31 LAIIGPSGSGKSTLAR--LILGL 51

Predicted kinase, contains AAA domain [General function prediction only];

                         10        20        30
                 ....*....|....*....|....*....|..
gi 742851398  27 IVVIIGPSGSGKTLLAKR--ALIDGLFISPDE 56
Cdd:COG0645    1 LILVCGLPGSGKSTLARAlaERLGAVRLRSDV 32

Uridine kinase [Nucleotide transport and metabolism]; Uridine kinase is part of the Pathway/BioSystem: Pyrimidine salvage

                         10
                 ....*....|....*....
gi 742851398  26 LIVVIIGPSGSGKTLLAKR 44
Cdd:COG0572    8 RIIGIAGPSGSGKTTFARR 26

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLfISPDE---PIAGEKfIQSLSNKD 71
Cdd:cd03261   28 ILAIIGPSGSGKSTLLR--LIVGL-LRPDSgevLIDGED-ISGLSEAE 71

Predicted kinase [General function prediction only];

                         10        20        30
                 ....*....|....*....|....*....|
gi 742851398  27 IVVIIGPSGSGKTLLAKRALIDGLFISPDE 56
Cdd:COG4639    4 LVVLIGLPGSGKSTFARRLFAPTEVVSSDD 33

Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];

                         10        20
                 ....*....|....*....|
gi 742851398  25 NLIvvIIGPSGSGKTLLAKR 44
Cdd:COG0606  213 NLL--MIGPPGSGKTMLARR 230

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742851398  22 KDTNL------IVVIIGPSGSGK-TLLakRaLIDGLfispDEPIAGEkfiqslsnkdIIVDDVVLFDM----RNV 85
Cdd:COG3839   20 KDIDLdiedgeFLVLLGPSGCGKsTLL--R-MIAGL----EDPTSGE----------ILIGGRDVTDLppkdRNI 77

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLfispDEPIAGEkfiqslsnkdIIVDDVVLFDM----RNV 85
Cdd:cd03259   28 FLALLGPSGCGKTTLLR--LIAGL----ERPDSGE----------ILIDGRDVTGVpperRNI 74

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLFispdEPIAGEkfiqslsnkdIIVDDVvlfDMRNV 85
Cdd:COG2274  503 RVAIVGRSGSGKSTLLK--LLLGLY----EPTSGR----------ILIDGI---DLRQI 542

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

                         10        20        30
                 ....*....|....*....|....*....|
gi 742851398  27 IVVIIGPSGSGKTLLAKraLIDGLfISPDE 56
Cdd:COG1122   29 FVAIIGPNGSGKSTLLR--LLNGL-LKPTS 55