NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|742402016|ref|WP_038881141|]
View 

MULTISPECIES: mechanosensitive channel protein [Cronobacter]

Protein Classification

mechanosensitive ion channel family protein( domain architecture ID 11485356)

mechanosensitive ion channel family protein functions in osmotic regulation in response to changing environmental and developmental signals; similar to Escherichia coli moderate conductance mechanosensitive channel YbiO

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-727 0e+00

putative mechanosensitive channel protein; Provisional


:

Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1338.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016   1 MPWILLLLVSLFSVSANAVSLPAAVVGASTTQkSETPPAEPDADKKRAAYAALADVLENEASRKALIEQLRQAAATPADQ 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDS-TTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  81 PTPVIKPPVNNEEdKTVLENVTEVTRHYGGEFAGRFAQLHRNITNAPHKPFNEKTFFNALSHFSLLAVSVFLFYFAVRAC 160
Cdd:PRK11465  80 PVPKIVPPTLVEE-KTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLC 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 161 AIPLYRKMGQWGRRKNIHRASWVQLPLMIILAFLIDLALLALTLFVGQLAIEMMNAGSRTIARQQGLFLNAFALIEFFKA 240
Cdd:PRK11465 159 ALPLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 241 ILRLMFSPRFPSLRPFVISDASARYWHLRLSGLSSLIGYGLLVAVPIISAQVNVQVGALANVIIMLTMTAWALYLIFHNK 320
Cdd:PRK11465 239 ILRLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNK 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 321 RAITAGLTRLADRSLAFFSLFIRAFALIWHWLASAYFIVLFFFSLFDPGNSLKTMMGASLKTLAIVSVAAFICGVFTRWL 400
Cdd:PRK11465 319 KEITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWI 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 401 SKTITLSPPVQRNYPELQKRLNGWLSVSLKLARFLTVCVAVMLLLNAWGLFDFWTWLTVGAGEKAVDILIRISLIVFFSA 480
Cdd:PRK11465 399 AKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSA 478

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 481 VGWTLLASLIESRLASDIHGRPMPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTL 560
Cdd:PRK11465 479 VGWTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTL 558

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 561 VKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSFVANYDVDRFEE 640
Cdd:PRK11465 559 VKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHED 638

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 641 TEKANRALRAAVDELMEQEDIRMLVIGEPNVVGIVGLTNTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIRPPVQ 720
Cdd:PRK11465 639 ADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQ 718


                 ....*..
gi 742402016 721 TVQVMQP 727
Cdd:PRK11465 719 TYQVLPA 725
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-727 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1338.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016   1 MPWILLLLVSLFSVSANAVSLPAAVVGASTTQkSETPPAEPDADKKRAAYAALADVLENEASRKALIEQLRQAAATPADQ 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDS-TTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  81 PTPVIKPPVNNEEdKTVLENVTEVTRHYGGEFAGRFAQLHRNITNAPHKPFNEKTFFNALSHFSLLAVSVFLFYFAVRAC 160
Cdd:PRK11465  80 PVPKIVPPTLVEE-KTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLC 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 161 AIPLYRKMGQWGRRKNIHRASWVQLPLMIILAFLIDLALLALTLFVGQLAIEMMNAGSRTIARQQGLFLNAFALIEFFKA 240
Cdd:PRK11465 159 ALPLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 241 ILRLMFSPRFPSLRPFVISDASARYWHLRLSGLSSLIGYGLLVAVPIISAQVNVQVGALANVIIMLTMTAWALYLIFHNK 320
Cdd:PRK11465 239 ILRLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNK 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 321 RAITAGLTRLADRSLAFFSLFIRAFALIWHWLASAYFIVLFFFSLFDPGNSLKTMMGASLKTLAIVSVAAFICGVFTRWL 400
Cdd:PRK11465 319 KEITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWI 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 401 SKTITLSPPVQRNYPELQKRLNGWLSVSLKLARFLTVCVAVMLLLNAWGLFDFWTWLTVGAGEKAVDILIRISLIVFFSA 480
Cdd:PRK11465 399 AKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSA 478

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 481 VGWTLLASLIESRLASDIHGRPMPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTL 560
Cdd:PRK11465 479 VGWTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTL 558

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 561 VKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSFVANYDVDRFEE 640
Cdd:PRK11465 559 VKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHED 638

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 641 TEKANRALRAAVDELMEQEDIRMLVIGEPNVVGIVGLTNTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIRPPVQ 720
Cdd:PRK11465 639 ADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQ 718


                 ....*..
gi 742402016 721 TVQVMQP 727
Cdd:PRK11465 719 TYQVLPA 725
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
442-724 1.02e-40

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 150.41  E-value: 1.02e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 442 MLLLNAWGLFDFWTWLTVGAGEkAVDILIRISLIVFFSAVGWTLLASLIESRLASdihgrpmpSARTRTLLTLFRNALAV 521
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 522 IISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 601
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 602 RQDTGAYHIIPWSSI--TTFANFVRGIGS-FVANYDVDRFEETEKANRALRAAVDELMEqedirmlVIGEPNVVGIVGLT 678
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEELPR-------ILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 742402016 679 NTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIRPPVQTVQV 724
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 516-716 2.30e-38

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 141.58  E-value: 2.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  516 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMS 595
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  596 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSFVANYDVDRFEETEKANRALRAAVDELMEQEDIrMLVIGEPNVV 672
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLV-LKDPEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 742402016  673 GIVGLTNTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIR 716
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
 
Name Accession Description Interval E-value
PRK11465 PRK11465
putative mechanosensitive channel protein; Provisional
 1-727 0e+00

putative mechanosensitive channel protein; Provisional


Pssm-ID: 183147 [Multi-domain]  Cd Length: 741  Bit Score: 1338.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016   1 MPWILLLLVSLFSVSANAVSLPAAVVGASTTQkSETPPAEPDADKKRAAYAALADVLENEASRKALIEQLRQAAATPADQ 80
Cdd:PRK11465   1 MRWILFILFCLLGAPAHAVSIPGVTTTTSTDS-TTEPAPEPDIEQKKAAYAALADVLDNDTSRKELIDQLRTAAATPPAE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  81 PTPVIKPPVNNEEdKTVLENVTEVTRHYGGEFAGRFAQLHRNITNAPHKPFNEKTFFNALSHFSLLAVSVFLFYFAVRAC 160
Cdd:PRK11465  80 PVPKIVPPTLVEE-KTVLQNVTEVSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFLMLAVLVFGFYWLIRLC 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 161 AIPLYRKMGQWGRRKNIHRASWVQLPLMIILAFLIDLALLALTLFVGQLAIEMMNAGSRTIARQQGLFLNAFALIEFFKA 240
Cdd:PRK11465 159 ALPLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQLLSDNLNAGSRTIAFQQSLFLNAFALIEFFKA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 241 ILRLMFSPRFPSLRPFVISDASARYWHLRLSGLSSLIGYGLLVAVPIISAQVNVQVGALANVIIMLTMTAWALYLIFHNK 320
Cdd:PRK11465 239 ILRLIFCPNVPELRPFTIQDASARYWNRRLSWLSSLIGYGLIVAVPIISNQVNVQVGALANVIIMLCMTVWALYLIFRNK 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 321 RAITAGLTRLADRSLAFFSLFIRAFALIWHWLASAYFIVLFFFSLFDPGNSLKTMMGASLKTLAIVSVAAFICGVFTRWL 400
Cdd:PRK11465 319 KEITQHLLNLAERSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFTRWI 398

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 401 SKTITLSPPVQRNYPELQKRLNGWLSVSLKLARFLTVCVAVMLLLNAWGLFDFWTWLTVGAGEKAVDILIRISLIVFFSA 480
Cdd:PRK11465 399 AKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLNAWGLFDFWNWLQNGAGEKTVDILIRIALILFFSA 478

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 481 VGWTLLASLIESRLASDIHGRPMPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTL 560
Cdd:PRK11465 479 VGWTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTL 558

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 561 VKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSFVANYDVDRFEE 640
Cdd:PRK11465 559 VKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHED 638

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 641 TEKANRALRAAVDELMEQEDIRMLVIGEPNVVGIVGLTNTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIRPPVQ 720
Cdd:PRK11465 639 ADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLTNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQ 718


                 ....*..
gi 742402016 721 TVQVMQP 727
Cdd:PRK11465 719 TYQVLPA 725
MscS COG0668
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
442-724 1.02e-40

Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440432 [Multi-domain]  Cd Length: 276  Bit Score: 150.41  E-value: 1.02e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 442 MLLLNAWGLFDFWTWLTVGAGEkAVDILIRISLIVFFSAVGWTLLASLIESRLASdihgrpmpSARTRTLLTLFRNALAV 521
Cdd:COG0668    1 EALAQLWSLLGLLLLLGELLLA-LLPKLLLALLILLIGWLLIRLLRRLIRRLLRR--------ARRDRTLLPLLRNILKI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 522 IISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGV 601
Cdd:COG0668   72 LIVIIAILLILSILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 602 RQDTGAYHIIPWSSI--TTFANFVRGIGS-FVANYDVDRFEETEKANRALRAAVDELMEqedirmlVIGEPNVVGIVGLT 678
Cdd:COG0668  152 RTLDGRLVTIPNSKIlsSPITNYSRGPTRrVDVTIGVDYDTDIDKARELLKEILEELPR-------ILKDPAVVGVTELG 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 742402016 679 NTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIRPPVQTVQV 724
Cdd:COG0668  225 DSSVNLRVRAWTKPGDYWDVRRDIRERIKAALDEAGIEIPFPTRTV 270
MS_channel pfam00924
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ...
 516-716 2.30e-38

Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.


Pssm-ID: 459999 [Multi-domain]  Cd Length: 203  Bit Score: 141.58  E-value: 2.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  516 RNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMS 595
Cdd:pfam00924   1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016  596 IRSVGVRQDTGAYHIIPWSSITT--FANFVR-GIGSFVANYDVDRFEETEKANRALRAAVDELMEQEDIrMLVIGEPNVV 672
Cdd:pfam00924  81 LRTTTIRTFDGRLVTIPNSSILTsnIINYSRsPTRRVELSIGVAYSSDPDKLEKVIEILKEAAYEHPLV-LKDPEPPVVF 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 742402016  673 GIVGLTNTAFTIRVTFTTQPLKQWTVRFALDGMVKKHFDLAGIR 716
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTLPGEYFNVRSELNLRIKKALEENGIE 203
MscK COG3264
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];
457-729 6.04e-20

Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442495 [Multi-domain]  Cd Length: 281  Bit Score: 90.65  E-value: 6.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 457 LTVGAGEKAVDILIRISLIVFFSAVGWTLLASLIESRLASDIHGRPmpsartrTLLTLFRNALAVIISTITIMIVLSEIG 536
Cdd:COG3264   11 FLIGGISISLPNLLLALLILVVTYLLARLLSRLLERRLLRRTRLDP-------GLRYLISKLIRYLIIVLGLLIALSALG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 537 VNIAPLLAGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSI 616
Cdd:COG3264   84 IDLTALAALAGALGVGIGFGLQDIVSNFISGLILLFERPFRVGDWIEIGGTEGTVEEIGLRSTRIRTFDGEEVIIPNSEL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 617 TT--FANFVRG---------IGsfVAnYDVDrfeeTEKANRALRAAVDelmEQEDIrmLVIGEPNVVgIVGLTNTAFTIR 685
Cdd:COG3264  164 ITnpVINWSLSdprrrveipVG--VA-YGSD----LEKVRELLLEAAR---EHPRV--LKDPAPSVL-FTEFGDSSVNFE 230

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 742402016 686 VTF-TTQPLKQWTVRFALDGMVKKHFDLAGIR--PPVQTVQVMQPMP 729
Cdd:COG3264  231 LRFwVNDPRDRLRVRSDLNEAIKKAFREEGIEipFPQRDVHLRNPPG 277
PRK11281 PRK11281
mechanosensitive channel MscK;
555-598 1.71e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 1.71e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 742402016  555 FGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRS 598
Cdd:PRK11281  918 FGLQEIFANFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRA 961
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 555-597 4.40e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 40.42  E-value: 4.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 742402016  555 FGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIR 597
Cdd:PRK10929  915 FGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTR 957
PRK10334 PRK10334
small-conductance mechanosensitive channel MscS;
465-724 8.19e-03

small-conductance mechanosensitive channel MscS;


Pssm-ID: 182386 [Multi-domain]  Cd Length: 286  Bit Score: 39.13  E-value: 8.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 465 AVDILIRISLIVffsaVGwtllasLIESRLASDIHGRPMPSARTRTLLTLFRNALAVI-ISTITIMIVLSEIGVNIAPLL 543
Cdd:PRK10334  28 AVNIVAALAIII----VG------LIIARMISNAVNRLMISRKIDATVADFLSALVRYgIIAFTLIAALGRVGVQTASVI 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 544 AGAGALGLAVSFGSQTLVKDIITGIFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSIT--TFAN 621
Cdd:PRK10334  98 AVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADGKIIVIPNGKIIagNIIN 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742402016 622 FVRG-------IGSFVANYDVDRfeetekanraLRAAVDELMEQEDiRMLVIGEPNV-VGIVGLTNTAFTIRVTFTTQPL 693
Cdd:PRK10334 178 FSREpvrrnefIIGVAYDSDIDQ----------VKQILTNIIQSED-RILKDREMTVrLNELGASSINFVVRVWSNSGDL 246

                        250       260       270
                 ....*....|....*....|....*....|.
gi 742402016 694 KQwtVRFALDGMVKKHFDLAGIRPPVQTVQV 724
Cdd:PRK10334 247 QN--VYWDVLERIKREFDAAGISFPYPQMDV 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH