|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
16-477 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 649.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 16 MRRVRHIHFVgiggagmggiaEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEI 95
Cdd:COG0773 1 LDKIMHIHFIgiggigmsglaEILLALGYKVSGSDLAESPMTERLEALGIPVFIGHDAENIDDADLVVVSSAIPRDNPEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 96 VAAREARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLVKAAGTHARLGSSRYLIAEA 175
Cdd:COG0773 81 VAARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 176 DESDASFLHLQPMVAVVTNIEADHMDTYqGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSED 255
Cdd:COG0773 161 DESDGSFLHYSPDIAVVTNIEADHLDIY-GDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPVITYGFSED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 256 ADVRIEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGEfp 335
Cdd:COG0773 240 ADYRAENIRIDGGGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFELKGE-- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 336 lepvngkAGSAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEA 415
Cdd:COG0773 318 -------VGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRDFLDEFAEALSLADEVILLDIYAAREK 390
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742394357 416 PIPGADSRSLCRTIRSRGKlDPILVSDADTVPETLAQLLQDEDLVLVQGAGNVGKIARKLAE 477
Cdd:COG0773 391 PIPGVSSEDLAEAIRKRGK-DVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
21-476 |
0e+00 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 641.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 21 HIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEIVAARE 100
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKRLEALGIPIYIGHSAENLDDADVVVVSAAIKDDNPEIVEAKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 101 ARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDA 180
Cdd:TIGR01082 81 RGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADESDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 181 SFLHLQPMVAVVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFS-EDADVR 259
Cdd:TIGR01082 161 SFLHLQPNVAIVTNIEPDHLDTYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKATEQVITYGGSgEDADYR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 260 IEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGEFPLepv 339
Cdd:TIGR01082 241 AENIQQSGAEGKFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRFEILGEFGG--- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 340 ngkagsAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEAPIPG 419
Cdd:TIGR01082 318 ------VLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRTRDLFDDFAKVLSDADELILLDIYAAGEEPING 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 742394357 420 ADSRSLCRTIRSRGKLDPILVSDADTVPETLAQLLQDEDLVLVQGAGNVGKIARKLA 476
Cdd:TIGR01082 392 IDGKSLARKITQLGKIEPYFVPDLAELVEFLAAVLQSGDLILTMGAGDIIKLARELL 448
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
16-485 |
4.82e-91 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 294.42 E-value: 4.82e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 16 MRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEI 95
Cdd:PRK14573 1 MMKSLFYHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVEKLKAKGARFFLGHQEEHVPEDAVVVYSSSISKDNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 96 VAAREARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLvKAAGTHARLGSSRYLIAEA 175
Cdd:PRK14573 81 LSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGL-NQEGLNGYSGSSEYFVAEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 176 DESDASFLHLQPMVAVVTNIEADHMDTYQGDFENLKQTFINFLH-----NLPFYGRavmciDDPvvrELLPRVGRHitTY 250
Cdd:PRK14573 160 DESDGSLKHYTPEFSVITNIDNEHLSNFEGDRELLLASIQDFARkvqqiNKCFYNG-----DCP---RLKGCLQGH--SY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 251 GFSEDADVRIEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRfdf 330
Cdd:PRK14573 230 GFSSSCDLHILSYYQEGWRSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRR--- 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 331 lgefpLEPVNgKAGSAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVY 410
Cdd:PRK14573 307 -----LERKN-SSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDSFPSAFQDADEVILTDVY 380
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742394357 411 AAGEAPIPGADSRSLCRTIRSRGKLDPILVSDADTVPEtLAQLLQDEDLVLVQGAGNVGKIARKLAELKlqpPKK 485
Cdd:PRK14573 381 SAGEEPEDSISYQKLAEAISQSSIVKCTYVPFHEIQRY-LEQSIRVHDVCVSLGAGNIYTLGEALKDFE---PKK 451
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
21-120 |
8.17e-18 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 78.04 E-value: 8.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 21 HIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNpvtqqLSALGATIYFNHRPENvldasvvvvstAISADNPEIVAARE 100
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIES-----LIALGAAAVVGHDAAN-----------NISPDNPELEAAKV 64
|
90 100
....*....|....*....|
gi 742394357 101 ARIPVIRRAEMLAELMRFRH 120
Cdd:pfam01225 65 PGIPVIDRREALAELAAAFY 84
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
16-477 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 649.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 16 MRRVRHIHFVgiggagmggiaEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEI 95
Cdd:COG0773 1 LDKIMHIHFIgiggigmsglaEILLALGYKVSGSDLAESPMTERLEALGIPVFIGHDAENIDDADLVVVSSAIPRDNPEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 96 VAAREARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLVKAAGTHARLGSSRYLIAEA 175
Cdd:COG0773 81 VAARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 176 DESDASFLHLQPMVAVVTNIEADHMDTYqGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSED 255
Cdd:COG0773 161 DESDGSFLHYSPDIAVVTNIEADHLDIY-GDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPVITYGFSED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 256 ADVRIEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGEfp 335
Cdd:COG0773 240 ADYRAENIRIDGGGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFELKGE-- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 336 lepvngkAGSAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEA 415
Cdd:COG0773 318 -------VGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRDFLDEFAEALSLADEVILLDIYAAREK 390
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 742394357 416 PIPGADSRSLCRTIRSRGKlDPILVSDADTVPETLAQLLQDEDLVLVQGAGNVGKIARKLAE 477
Cdd:COG0773 391 PIPGVSSEDLAEAIRKRGK-DVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
21-476 |
0e+00 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 641.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 21 HIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEIVAARE 100
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKRLEALGIPIYIGHSAENLDDADVVVVSAAIKDDNPEIVEAKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 101 ARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDA 180
Cdd:TIGR01082 81 RGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADESDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 181 SFLHLQPMVAVVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFS-EDADVR 259
Cdd:TIGR01082 161 SFLHLQPNVAIVTNIEPDHLDTYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKATEQVITYGGSgEDADYR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 260 IEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGEFPLepv 339
Cdd:TIGR01082 241 AENIQQSGAEGKFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRFEILGEFGG--- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 340 ngkagsAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEAPIPG 419
Cdd:TIGR01082 318 ------VLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRTRDLFDDFAKVLSDADELILLDIYAAGEEPING 391
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 742394357 420 ADSRSLCRTIRSRGKLDPILVSDADTVPETLAQLLQDEDLVLVQGAGNVGKIARKLA 476
Cdd:TIGR01082 392 IDGKSLARKITQLGKIEPYFVPDLAELVEFLAAVLQSGDLILTMGAGDIIKLARELL 448
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
16-485 |
4.82e-91 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 294.42 E-value: 4.82e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 16 MRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLSALGATIYFNHRPENVLDASVVVVSTAISADNPEI 95
Cdd:PRK14573 1 MMKSLFYHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVEKLKAKGARFFLGHQEEHVPEDAVVVYSSSISKDNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 96 VAAREARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEARLDPTFVNGGLvKAAGTHARLGSSRYLIAEA 175
Cdd:PRK14573 81 LSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGL-NQEGLNGYSGSSEYFVAEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 176 DESDASFLHLQPMVAVVTNIEADHMDTYQGDFENLKQTFINFLH-----NLPFYGRavmciDDPvvrELLPRVGRHitTY 250
Cdd:PRK14573 160 DESDGSLKHYTPEFSVITNIDNEHLSNFEGDRELLLASIQDFARkvqqiNKCFYNG-----DCP---RLKGCLQGH--SY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 251 GFSEDADVRIEDYRQIGPQGHFTLSRQDKPLLTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRfdf 330
Cdd:PRK14573 230 GFSSSCDLHILSYYQEGWRSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRR--- 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 331 lgefpLEPVNgKAGSAMLVDDYGHHPTEVDATLKAARAGWPDKRLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVY 410
Cdd:PRK14573 307 -----LERKN-SSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDSFPSAFQDADEVILTDVY 380
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742394357 411 AAGEAPIPGADSRSLCRTIRSRGKLDPILVSDADTVPEtLAQLLQDEDLVLVQGAGNVGKIARKLAELKlqpPKK 485
Cdd:PRK14573 381 SAGEEPEDSISYQKLAEAISQSSIVKCTYVPFHEIQRY-LEQSIRVHDVCVSLGAGNIYTLGEALKDFE---PKK 451
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
39-365 |
1.20e-30 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 123.65 E-value: 1.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 39 LANEGYQISGSDLAPNPVT--QQLSALGATIYF-NHRPENVLDASVVVVSTAISADNPEIVAAREARIPVIrrAEMlaEL 115
Cdd:COG0771 23 LAKLGAEVTVSDDRPAPELaaAELEAPGVEVVLgEHPEELLDGADLVVKSPGIPPDHPLLKAARAAGIPVI--GEI--EL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 116 -MRFRHG--IAIAGTHGKTTTTAMVSSIyaearldptfvngglVKAAGTHARLG-------SSryLIAEADESDA----- 180
Cdd:COG0771 99 aYRLSPApiIAITGTNGKTTTTTLIGHI---------------LKAAGLRVAVGgnigtplLD--LLLEPEPPDVyvlel 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 181 -SF-LH----LQPMVAVVTNIEADHMDTYqGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSE 254
Cdd:COG0771 162 sSFqLEttpsLRPDVAVILNITPDHLDRH-GSMEAYAAAKARIFANQTPDDYAVLNADDPLTRALAEEAKARVVPFSLKE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 255 --DADVRIEDyrqigpqGHFTLSRQDKPLLTVT-LNAPGRHNAL---------NAAaavavateeGIDDEDILRALAGFQ 322
Cdd:COG0771 241 plEGGAGLED-------GKLVDRASGEELLPVDdLRLPGRHNLEnalaalaaaRAL---------GVPPEAIREALRSFK 304
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 742394357 323 GTGRRFDFLGEfplepVNG-------KAgsamlvddyghhpTEVDATLKA 365
Cdd:COG0771 305 GLPHRLEFVAE-----INGvrfindsKA-------------TNPDATLAA 336
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
37-368 |
2.23e-29 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 119.75 E-value: 2.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 37 EVLANEGYQISGSDLAPN----PVTQQLSALGATIYFNHR-PENVLDASVVVVSTAISADNPEIVAAREARIPVIRRAEM 111
Cdd:TIGR01087 16 RFLHKKGAEVTVTDLKPNeelePSMGQLRLNEGSVLHTGLhLEDLNNADLVVKSPGIPPDHPLVQAAAKRGIPVVGDIEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 112 LAELMRfRHGIAIAGTHGKTTTTAMVSSIyAEARLDPTFVNGGLVKAAGTHARLGSSRYLIAEAdesdASF-LH----LQ 186
Cdd:TIGR01087 96 FLRLVP-LPVVAITGTNGKTTTTSLLYHL-LKAAGLKAFLGGNIGTPALEVLDQEGAELYVLEL----SSFqLEttesLR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 187 PMVAVVTNIEADHMDtYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSEDADVRIEDyrqi 266
Cdd:TIGR01087 170 PEIALILNISEDHLD-WHGSFEDYVAAKLKIFARQTEGDVAVLNADDPRFARLAQKSKAQVIWFSVEKDAERGLCI---- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 267 gPQGHFTLSRQDKPLltvtlNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGEfplepVNGKagsa 346
Cdd:TIGR01087 245 -RDGGLYLKPNDLEG-----SLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEYVGQ-----KNGV---- 309
|
330 340
....*....|....*....|..
gi 742394357 347 MLVDDygHHPTEVDATLKAARA 368
Cdd:TIGR01087 310 HFYND--SKATNVHATLAALSA 329
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
79-379 |
4.10e-21 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 95.92 E-value: 4.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 79 ASVVVVSTAisadnpeiVAAREARIPVI-----RRAemLAEL-MRFrHG--------IAIAGTHGKTTTTAMVSSIYAEA 144
Cdd:COG0769 37 AVAVVTEAP--------GALLAAGVPVIvvpdpRAA--LALLaAAF-YGhpsqklklIGVTGTNGKTTTTYLLAQILRAL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 145 RLDP-------TFVNGGLVKAAGT-------HArlgssryLIAEADESDASF-----------------LHLQpmVAVVT 193
Cdd:COG0769 106 GKKTgligtvgNGIGGELIPSSLTtpealdlQR-------LLAEMVDAGVTHvvmevsshaldqgrvdgVRFD--VAVFT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 194 NIEADHMDtYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSEDADVRIEDYRqIGPQG-HF 272
Cdd:COG0769 177 NLTRDHLD-YHGTMEAYFAAKARLFDQLGPGGAAVINADDPYGRRLAAAAPARVITYGLKADADLRATDIE-LSADGtRF 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 273 TLSRQDKPLlTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQG-TGRrfdflgefpLEPVNGKAGsAMLVDD 351
Cdd:COG0769 255 TLVTPGGEV-EVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEKLKGvPGR---------MERVDGGQG-PTVIVD 323
|
330 340
....*....|....*....|....*...
gi 742394357 352 YGHHPTEVDATLKAARAgWPDKRLVMIF 379
Cdd:COG0769 324 YAHTPDALENVLEALRP-HTKGRLIVVF 350
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
38-333 |
2.11e-19 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 90.42 E-value: 2.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 38 VLANEGYQISGSDL-APNPVTQQLSALGA---TIYFNHRPENVLDAS-VVVVSTAISADNPEIVAAREARIPVIRRAEML 112
Cdd:PRK14106 23 FLKKLGAKVILTDEkEEDQLKEALEELGElgiELVLGEYPEEFLEGVdLVVVSPGVPLDSPPVVQAHKKGIEVIGEVELA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 113 AELMRfRHGIAIAGTHGKTTTTAMVSSIYAEARlDPTFVNGGlvkaagtharLGSSryLIAEADESDA---------SF- 182
Cdd:PRK14106 103 YRFSK-APIVAITGTNGKTTTTTLLGEIFKNAG-RKTLVAGN----------IGYP--LIDAVEEYGEddiivaevsSFq 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 183 ----LHLQPMVAVVTNIEADHMDTYqGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRV-GRHITtygFSEdad 257
Cdd:PRK14106 169 letiKEFKPKVGCILNITPDHLDRH-KTMENYIKAKARIFENQRPSDYTVLNYDDPRTRSLAKKAkARVIF---FSR--- 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 258 vriedyRQIGPQGHFTlsRQDKPLLTV-----------TLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGR 326
Cdd:PRK14106 242 ------KSLLEEGVFV--KNGKIVISLggkeeevididEIFIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEH 313
|
....*..
gi 742394357 327 RFDFLGE 333
Cdd:PRK14106 314 RIEFVAE 320
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
79-351 |
7.10e-19 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 89.01 E-value: 7.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 79 ASVVVVSTAISADNPEIV----------AAREAR----IPVIrraemlaelmrfrhgiAIAGTHGKTTTTAMVSSIYAEA 144
Cdd:COG0770 62 AAAALVSRPLPADLPLIVvddtlkalqqLAAAHRarfnIPVI----------------AITGSNGKTTTKEMLAAVLSTK 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 145 rldptfvnGGLVKAAG----------THARLGSS-RYLIAEADesdASflHL----------QPMVAVVTNIEADHMDTY 203
Cdd:COG0770 126 --------GKVLATPGnfnneigvplTLLRLPEDhEFAVLEMG---MN--HPgeiaylariaRPDIAVITNIGPAHLEGF 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 204 qGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSEDADVRIEDYRQIGPQGHFTLSRQDKPLlT 283
Cdd:COG0770 193 -GSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAKARVLTFGLSEDADVRAEDIELDEDGTRFTLHTPGGEL-E 270
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742394357 284 VTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRfdflgefpLEPVNGkAGSAMLVDD 351
Cdd:COG0770 271 VTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGR--------LEVIEG-AGGVTLIDD 329
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
21-120 |
8.17e-18 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 78.04 E-value: 8.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 21 HIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNpvtqqLSALGATIYFNHRPENvldasvvvvstAISADNPEIVAARE 100
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIES-----LIALGAAAVVGHDAAN-----------NISPDNPELEAAKV 64
|
90 100
....*....|....*....|
gi 742394357 101 ARIPVIRRAEMLAELMRFRH 120
Cdd:pfam01225 65 PGIPVIDRREALAELAAAFY 84
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
124-295 |
1.63e-17 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 80.81 E-value: 1.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 124 IAGTHGKTTTTAMVSSIYAEArldptfvnGGLVKAAGTHARLGSSRY--------LIAEADESDASFL------------ 183
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLA--------GGVIGTIGTYIGKSGNTTnnaiglplTLAEMVEAGAEYAvlevsshglgeg 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 184 ----HLQPMVAVVTNIEADHMDtYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPV---VRELLPRVGRHITTYGFSEDA 256
Cdd:pfam08245 73 rlsgLLKPDIAVFTNISPDHLD-FHGTMENYAKAKAELFEGLPEDGIAVINADDPYgafLIAKLKKAGVRVITYGIEGEA 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 742394357 257 DVRIEDYRQiGPQG-HFTLSRQDKPLLTVTLNAPGRHNAL 295
Cdd:pfam08245 152 DLRAANIEL-SSDGtSFDLFTVPGGELEIEIPLLGRHNVY 190
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
79-379 |
1.14e-11 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 67.42 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 79 ASVVVVSTAISadnPEIVAAREARIPVIRRAEMLAELMRFRHG--------IAIAGTHGKTTTTAMVSSIYAE------- 143
Cdd:PRK11929 67 AAAVLVEAEGE---DQVAAADALVLPVADLRKALGELAARWYGrpseqlslVAVTGTNGKTSCAQLLAQLLTRlgkpcgs 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 144 -----ARLDPTFVNGGLV--KAAGTHARLG-----SSRYLIAEADE---SDASFLHLQPMVAVVTNIEADHMDtYQGDFE 208
Cdd:PRK11929 144 igtlgARLDGRLIPGSLTtpDAIILHRILArmraaGADAVAMEASShglEQGRLDGLRIAVAGFTNLTRDHLD-YHGTMQ 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 209 NLKQTFINFLHNLPFYGRAVMCIDDPVVRELLP--RVGRHITTYGFSEDADVRIEDYRQIGPQGHFTLSRQDKpLLTVTL 286
Cdd:PRK11929 223 DYEEAKAALFSKLPGLGAAVINADDPAAARLLAalPRGLKVGYSPQNAGADVQARDLRATAHGQVFTLATPDG-SYQLVT 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 287 NAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRFDFLGefplePVNGKAGSAMLVdDYGHHPTEVDATLKAA 366
Cdd:PRK11929 302 RLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPVPGRMERVG-----PTAGAQGPLVVV-DYAHTPDALAKALTAL 375
|
330
....*....|....*
gi 742394357 367 R--AGWPDKRLVMIF 379
Cdd:PRK11929 376 RpvAQARNGRLVCVF 390
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
336-420 |
1.34e-11 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 60.44 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 336 LEPVnGKAGSAMLVDDYGHHPTEVDATLKAARaGWPDKRLVMIFQPHRyTRTRDLYDDFANVLSQV-DVLLMLDVYAAGE 414
Cdd:pfam02875 5 LEVV-GENNGVLVIDDYAHNPDAMEAALRALR-NLFPGRLILVFGGMG-DRDAEFHALLGRLAAALaDVVILTGDYPRAE 81
|
....*.
gi 742394357 415 APIPGA 420
Cdd:pfam02875 82 DPGAII 87
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
122-379 |
2.10e-10 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 62.72 E-value: 2.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 122 IAIAGTHGKTTTTAMVSSIYAEARLDPTFV-------NGGLVKAAGTH---------------ARLGSSRYLIAEAdESD 179
Cdd:TIGR01085 88 IGVTGTNGKTTTTSLIAQLLRLLGKKTGLIgtigyrlGGNDLIKNPAAlttpealtlqstlaeMVEAGAQYAVMEV-SSH 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 180 ASFLH-LQPM---VAVVTNIEADHMDtYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSED 255
Cdd:TIGR01085 167 ALAQGrVRGVrfdAAVFTNLSRDHLD-FHGTMENYFAAKASLFTELGLKRFAVINLDDEYGAQFVKRLPKDITVSAITQP 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 256 ADVRIEDYRQI-----GPQGHFTLSRQDKPLLtVTLNAPGRHNAL-NAAAAVAVATEEGIDDEDILRALAGFQGT-GRrf 328
Cdd:TIGR01085 246 ADGRAQDIKITdsgysFEGQQFTFETPAGEGH-LHTPLIGRFNVYnLLAALATLLHLGGIDLEDIVAALEKFRGVpGR-- 322
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 742394357 329 dflgefpLEPVNGKAGSAMLVdDYGHHPTEVDATLKAARAgWPDKRLVMIF 379
Cdd:TIGR01085 323 -------MELVDGGQKFLVIV-DYAHTPDALEKALRTLRK-HKDGRLIVVF 364
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
122-379 |
4.20e-10 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 61.69 E-value: 4.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 122 IAIAGTHGKTTTTAMVSSIYAEAR--------LDpTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFL------H--- 184
Cdd:PRK00139 98 IGVTGTNGKTTTAYLLAQILRLLGektaligtLG-NGIGGELIPSGLTTPDALDLQRLLAELVDAGVTYAamevssHald 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 185 ------LQPMVAVVTNIEADHMDtYQGDFENL---KQTFINFLhnlpfYGRAVMCIDDPVVRELLPRVgrhiTTYGFS-E 254
Cdd:PRK00139 177 qgrvdgLKFDVAVFTNLSRDHLD-YHGTMEDYlaaKARLFSEL-----GLAAVINADDEVGRRLLALP----DAYAVSmA 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 255 DADVRIEDYRqIGPQG-HFTLSRqdkpllTVTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQG-TGRrfdflg 332
Cdd:PRK00139 247 GADLRATDVE-YTDSGqTFTLVT------EVESPLIGRFNVSNLLAALAALLALGVPLEDALAALAKLQGvPGR------ 313
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 742394357 333 efpLEPVNGKAGSAMLVdDYGHHPTEVDATLKAARAgWPDKRLVMIF 379
Cdd:PRK00139 314 ---MERVDAGQGPLVIV-DYAHTPDALEKVLEALRP-HAKGRLICVF 355
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
122-365 |
1.88e-06 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 50.47 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 122 IAIAGTHGKTTTTAMVSSIYAEARLDptfvNGGLVKAAGTHARLGSSRYLIAEADESDASFLHL---------------Q 186
Cdd:PRK11929 606 VAITGSNGKTTTKEMIAAILAAWQGE----DRVLATEGNFNNEIGVPLTLLRLRAQHRAAVFELgmnhpgeiaylaaiaA 681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 187 PMVAVVTNIEADHMDtYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVG-RHITTYGFSEDADVRIEDYRQ 265
Cdd:PRK11929 682 PTVALVTNAQREHQE-FMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYTAIWAKLAGaRRVLRFGLQPGADVYAEKIAK 760
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 266 IGPQGhfTLSRQDKPLLT------VTLNAPGRHNALNAAAAVAVATEEGIDDEDILRALAGFQGTGRRfdflgefpLEPV 339
Cdd:PRK11929 761 DISVG--EAGGTRCQVVTpagsaeVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGR--------MQRR 830
|
250 260
....*....|....*....|....*.
gi 742394357 340 NGKAGSAMLVDDYGHHPTEVDATLKA 365
Cdd:PRK11929 831 RLSCGTRIIDDTYNANPDSMRAAIDV 856
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
101-257 |
4.60e-05 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 45.92 E-value: 4.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 101 ARIPVIrraemlaelmrfrhgiAIAGTHGKTTTTAMVSSIYAEARL-------DPTFVNGGLV-KAAGTHARlgSSRYLI 172
Cdd:PRK14016 478 GRIPIV----------------AVTGTNGKTTTTRLIAHILKLSGKrvgmtttDGVYIDGRLIdKGDCTGPK--SARRVL 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742394357 173 A----EA-----------------DESDasflhlqpmVAVVTNIEADH-----MDTyQGDFENLKQTFI-NFLHNlpfyG 225
Cdd:PRK14016 540 MnpdvEAavletarggilreglayDRCD---------VGVVTNIGEDHlglggINT-LEDLAKVKRVVVeAVKPD----G 605
|
170 180 190
....*....|....*....|....*....|...
gi 742394357 226 RAVMCIDDPVVRELLPRV-GRHITtygFSEDAD 257
Cdd:PRK14016 606 YAVLNADDPMVAAMAERCkGKVIF---FSMDPD 635
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