|
Name |
Accession |
Description |
Interval |
E-value |
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
343-610 |
1.25e-95 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 297.41 E-value: 1.25e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 343 EVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKAVY 422
Cdd:COG1250 1 EIKKVAVIGAGTMGAGIAAVFANA-GYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEEEADAALARITPTTDLAAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 423 ADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATT 502
Cdd:COG1250 80 ADADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 503 DEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGT-DAHEADHAL-DPLALPMTPFTLLAMVGIPVA 580
Cdd:COG1250 160 DETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYLNEAIRLLEEGVaSPEDIDAAMrLGFGFPMGPFELADLVGLDTA 239
|
250 260 270
....*....|....*....|....*....|
gi 738365679 581 QHVSESLSASFGAERFPVSANLQRLIDAGK 610
Cdd:COG1250 240 LAVLEVLYEALGDPRYRPPPLLKKLVEAGR 269
|
|
| fadB |
PRK11730 |
fatty acid oxidation complex subunit alpha FadB; |
84-712 |
4.70e-88 |
|
fatty acid oxidation complex subunit alpha FadB;
Pssm-ID: 183293 [Multi-domain] Cd Length: 715 Bit Score: 291.38 E-value: 4.70e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGAD----LSLIAGLTDDVgRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKg 159
Cdd:PRK11730 57 LTSAKDAFIVGADitefLSLFAAPEEEL-SQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDAR- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 160 FGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKNplDDNRMLDARAAhglGLMDRIVEGD-LLDAGLELAAALVAGDE 238
Cdd:PRK11730 135 IGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAG--KDVRAEDALKV---GAVDAVVAPEkLQEAALALLKQAIAGKL 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 239 SVAAE----LAAHRDRDVSDAAwdrALAALERLQAARPGRHLPARRHLEDLFTGARTRTRAESAQAEADALGTLLHSPEF 314
Cdd:PRK11730 210 DWKARrqpkLEPLKLSKIEAMM---SFTTAKGMVAQKAGKHYPAPMTAVKTIEAAAGLGRDEALELEAKGFVKLAKTNVA 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 315 RRTVYAFLG--LVQGRAKRPAgdpgrELAREVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQV 392
Cdd:PRK11730 287 RALVGIFLNdqYVKGKAKKLA-----KDAKPVKQAAVLGAGIMGGGIAYQSASK-GVPVIMKDINQKALDLGMTEAAKLL 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 393 EKMVSRGRLSAEDGEALAGLITADTDKAVYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVL 472
Cdd:PRK11730 361 NKQVERGKIDGAKMAGVLSSIRPTLDYAGFERVDVVVEAVVENPKVKAAVLAEVEQKVREDTILASNTSTISISLLAKAL 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 473 EHPERLVGFHFFNPVAVMPLVEIVRTEATTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGTDA 552
Cdd:PRK11730 441 KRPENFCGMHFFNPVHRMPLVEVIRGEKTSDETIATVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADF 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 553 HEADHALD-PLALPMTPFTLLAMVGIPVAQHVSESLsasfgAERFPvsanlQRLIDAGKTAIwakDVRPD---------- 621
Cdd:PRK11730 521 RQIDKVMEkQFGWPMGPAYLLDVVGIDTAHHAQAVM-----AEGFP-----DRMKKDYRDAI---DVLFEakrfgqkngk 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 622 ---RRDEEAAGATGEQIPEATAALLEQGSTPQ---TSEELLRRVEDALAEEIGLLLDERVVAAPEDVDLCMILGANWPLH 695
Cdd:PRK11730 588 gfyRYEEDKKGKPKKEVDPAVYELLAPVVQPKrefSDEEIIARMMIPMINEVVRCLEEGIVASPAEADMALVYGLGFPPF 667
|
650
....*....|....*..
gi 738365679 696 LGGITPYLDDCGAAERV 712
Cdd:PRK11730 668 RGGAFRYLDTLGVANYV 684
|
|
| fadJ |
PRK11154 |
fatty acid oxidation complex subunit alpha FadJ; |
84-720 |
4.65e-87 |
|
fatty acid oxidation complex subunit alpha FadJ;
Pssm-ID: 236864 [Multi-domain] Cd Length: 708 Bit Score: 288.72 E-value: 4.65e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGLTD-DVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKG-FG 161
Cdd:PRK11154 58 ISGKPDNFIAGADINMLAACKTaQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTvLG 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 162 LPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKNplddnRMLDARAAHGLGLMDRIVEGD-LLDAGLELAAAlvagdESV 240
Cdd:PRK11154 138 LPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTG-----KQLRAKQALKLGLVDDVVPHSiLLEVAVELAKK-----GKP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 241 AAELAAHRDRDVSDAAWDRAL---AALERLQAARPGrHLPA-RRHLEDLFTGArTRTRAESAQAEADALGTLLHSPEFRR 316
Cdd:PRK11154 208 ARRPLPVRERLLEGNPLGRALlfkQARKKTLAKTQG-NYPApERILDVVRTGL-EKGMSSGYEAEARAFGELAMTPESAA 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 317 TVYAFLGlvQGRAKRpagDPGREL-AREVRKVGIVGAGLMAGQLALVFARHLRVPVVMTDIDAERVERGLAGVRAQVEKM 395
Cdd:PRK11154 286 LRSIFFA--TTEMKK---DTGSDAkPRPVNKVGVLGGGLMGGGIAYVTATKAGLPVRIKDINPQGINHALKYSWDLLDKK 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 396 VSRGRLSAEDGEALAGLITADTDKAVYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHP 475
Cdd:PRK11154 361 VKRRHLKPSERDKQMALISGTTDYRGFKHADVVIEAVFEDLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARP 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 476 ERLVGFHFFNPVAVMPLVEIVRTEATTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGTDAHEA 555
Cdd:PRK11154 441 EQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALAKKQGKTPIVVRDGAGFYVNRILAPYINEAARLLLEGEPIEHI 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 556 DHALDPLALPMTPFTLLAMVGIPVAQHVSESLSASFGaERFPVSANLQRLIDAGKTAiwAKDVRPDRRDEEAAGATGEQI 635
Cdd:PRK11154 521 DAALVKFGFPVGPITLLDEVGIDVGTKIIPILEAALG-ERFSAPAAFDKLLNDDRKG--RKNGRGFYLYGQKGKKSKKQV 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 636 PEATAALLeqGSTPQT---SEELLRRVEDALAEEIGLLLDERVVAAPEDVDLCMILGANWPLHLGGITPYLDDCGAAERV 712
Cdd:PRK11154 598 DESVYPLL--GITPQSrlsANEIAERCVMLMLNEAVRCLDEGIIRSARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEVV 675
|
650
....*....|....*..
gi 738365679 713 N---------GRRFHPA 720
Cdd:PRK11154 676 AilerlaaqyGDRFTPC 692
|
|
| 3HCDH_N |
pfam02737 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ... |
346-526 |
2.55e-69 |
|
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.
Pssm-ID: 397037 [Multi-domain] Cd Length: 180 Bit Score: 224.72 E-value: 2.55e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 346 KVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKAVYADA 425
Cdd:pfam02737 1 KVAVIGAGTMGAGIAQVFALA-GLEVVLVDISEEALEKALERIESSLERLVEKGRITEEEVDAALARISFTTDLAAAVDA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 426 DIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATTDEV 505
Cdd:pfam02737 80 DLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPET 159
|
170 180
....*....|....*....|.
gi 738365679 506 VATAFELTRRLRKTGVLVHDA 526
Cdd:pfam02737 160 VATTVELAKKIGKTPVVVKDT 180
|
|
| fa_ox_alpha_mit |
TIGR02441 |
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ... |
84-721 |
6.65e-68 |
|
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).
Pssm-ID: 131494 [Multi-domain] Cd Length: 737 Bit Score: 237.43 E-value: 6.65e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGL-TDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKG-FG 161
Cdd:TIGR02441 65 ISGKPGSFVAGADIQMIAACkTAQEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTlLG 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 162 LPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKNplddnRMLDARAAHGLGLMDRIVegDLLDAGLELAA---------- 231
Cdd:TIGR02441 145 LPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTG-----KKIRADRAKKMGIVDQLV--DPLGPGLKPAEentieyleev 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 232 ALVAGDESVAAELAAHRDRDVSDAAWDRALA-----------ALERLQAARPGRHlPARRHLEDLFTGARTRTRAESAQA 300
Cdd:TIGR02441 218 AVKFAQGLANGKLSINRDKGLVHKITQYVMTnpfvrqqvyktAEDKVMKQTKGLY-PAPLKILDVVRTGYDQGPDAGYEA 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 301 EADALGTLLHSPEFRrtvyAFLGLVQGRA---KRPAGDPgrelAREVRKVGIVGAGLMAGQLALV-FARHLRVpvVMTDI 376
Cdd:TIGR02441 297 ESKAFGELSMTFESK----ALIGLFHGQTdckKNKFGKP----QRPVKTLAVLGAGLMGAGIAQVsVDKGLKT--VLKDA 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 377 DAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKAVYADADIVIEAVFEELEVKRTVFRELEGIVREDAIL 456
Cdd:TIGR02441 367 TPAGLDRGQQQVFKGLNKKVKRKKITSLERDSILSNLTPTLDYSGFKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCII 446
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 457 MTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLL 536
Cdd:TIGR02441 447 ASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHDGTSKDTLASAVAVGLKQGKVVIVVKDGPGFYTTRCLG 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 537 RMMGEVQNSFDEGTDAHEADHALDPLALPMTPFTLLAMVGIPVAQHVSESLSASFGaERFPvSANLQRLID--------- 607
Cdd:TIGR02441 527 PMLAEVIRLLQEGVDPKKLDKLTTKFGFPVGAATLADEVGVDVAEHVAEDLGKAFG-ERFG-GGSAELLSElvkagflgr 604
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 608 -AGKTAIWAKDVRPDRRDEEAagatgeqipEATAALLEQGSTPQTS----EELLRRVEDALAEEIGLLLDERVVAAPEDV 682
Cdd:TIGR02441 605 kSGKGIFIYQEGKKGSKKVNS---------DADEILAQYKLPPKAEvsspEDIQIRLVSRFVNEAVLCLEEGILASPSEG 675
|
650 660 670
....*....|....*....|....*....|....*....
gi 738365679 683 DLCMILGANWPLHLGGITPYLDDCGAAERVNGRRFHPAA 721
Cdd:TIGR02441 676 DIGAVFGLGFPPFLGGPFRFVDLYGADKLVDKMEKYAAA 714
|
|
| PRK05808 |
PRK05808 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
344-609 |
1.78e-63 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 180269 [Multi-domain] Cd Length: 282 Bit Score: 212.90 E-value: 1.78e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 344 VRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKAVYA 423
Cdd:PRK05808 3 IQKIGVIGAGTMGNGIAQVCAVA-GYDVVMVDISDAAVDRGLATITKSLDRLVKKGKMTEADKEAALARITGTTDLDDLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 424 DADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATTD 503
Cdd:PRK05808 82 DADLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATSD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 504 EVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGTDAHEADHALDPLAL--PMTPFTLLAMVGIPVAQ 581
Cdd:PRK05808 162 ATHEAVEALAKKIGKTPVEVKNAPGFVVNRILIPMINEAIFVLAEGVATAEDIDEGMKLGCnhPIGPLALADLIGLDTCL 241
|
250 260
....*....|....*....|....*...
gi 738365679 582 HVSESLSASFGAERFPVSANLQRLIDAG 609
Cdd:PRK05808 242 AIMEVLYEGFGDSKYRPCPLLRKMVAAG 269
|
|
| PLN02545 |
PLN02545 |
3-hydroxybutyryl-CoA dehydrogenase |
341-609 |
6.27e-58 |
|
3-hydroxybutyryl-CoA dehydrogenase
Pssm-ID: 215300 [Multi-domain] Cd Length: 295 Bit Score: 198.42 E-value: 6.27e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 341 AREVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKA 420
Cdd:PLN02545 1 MAEIKKVGVVGAGQMGSGIAQLAAAA-GMDVWLLDSDPAALSRGLDSISSSLARLVKKGKMSQEEADATLGRIRCTTNLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 421 VYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEA 500
Cdd:PLN02545 80 ELRDADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIRGAD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 501 TTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEG-TDAHEADHALDPLA-LPMTPFTLLAMVGIP 578
Cdd:PLN02545 160 TSDEVFDATKALAERFGKTVVCSQDYPGFIVNRILMPMINEAFYALYTGvASKEDIDTGMKLGTnHPMGPLHLADFIGLD 239
|
250 260 270
....*....|....*....|....*....|.
gi 738365679 579 VAQHVSESLSASFGAERFPVSANLQRLIDAG 609
Cdd:PLN02545 240 TCLSIMKVLHEGLGDSKYRPCPLLVQYVDAG 270
|
|
| PRK08268 |
PRK08268 |
3-hydroxy-acyl-CoA dehydrogenase; Validated |
344-609 |
3.32e-56 |
|
3-hydroxy-acyl-CoA dehydrogenase; Validated
Pssm-ID: 236211 [Multi-domain] Cd Length: 507 Bit Score: 200.07 E-value: 3.32e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 344 VRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKAVYA 423
Cdd:PRK08268 7 IATVAVIGAGAMGAGIAQVAAQA-GHTVLLYDARAGAAAAARDGIAARLAKLVEKGKLTAEQADAALARLRPVEALADLA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 424 DADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATTD 503
Cdd:PRK08268 86 DCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPERVAGLHFFNPVPLMKLVEVVSGLATDP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 504 EVVATAFELTRRLRKTGVLVHDATAFVVNRV-------LLRMMGEvqnsfdEGTDAHEADHAL-DPLALPMTPFTLLAMV 575
Cdd:PRK08268 166 AVADALYALARAWGKTPVRAKDTPGFIVNRAarpyyteALRVLEE------GVADPATIDAILrEAAGFRMGPFELMDLI 239
|
250 260 270
....*....|....*....|....*....|....*
gi 738365679 576 GIPVAQHVSESL-SASFGAERFPVSANLQRLIDAG 609
Cdd:PRK08268 240 GLDVNHAVMESVyRQFYQEPRFRPSLIQQELVAAG 274
|
|
| PRK07530 |
PRK07530 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
341-564 |
6.32e-54 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181018 [Multi-domain] Cd Length: 292 Bit Score: 187.52 E-value: 6.32e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 341 AREVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKA 420
Cdd:PRK07530 1 MMAIKKVGVIGAGQMGNGIAHVCALA-GYDVLLNDVSADRLEAGLATINGNLARQVAKGKISEEARAAALARISTATDLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 421 VYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEA 500
Cdd:PRK07530 80 DLADCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRGIA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738365679 501 TTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGTDAHE---------ADHALDPLAL 564
Cdd:PRK07530 160 TDEATFEAAKEFVTKLGKTITVAEDFPAFIVNRILLPMINEAIYTLYEGVGSVEaidtamklgANHPMGPLEL 232
|
|
| PRK07819 |
PRK07819 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
340-609 |
6.13e-48 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181133 [Multi-domain] Cd Length: 286 Bit Score: 170.94 E-value: 6.13e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 340 LAREVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDK 419
Cdd:PRK07819 1 MSDAIQRVGVVGAGQMGAGIAEVCARA-GVDVLVFETTEELATAGRNRIEKSLERAVSRGKLTERERDAALARLRFTTDL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 420 AVYADADIVIEAVFEELEVKRTVFRELEGIV-REDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRT 498
Cdd:PRK07819 80 GDFADRQLVIEAVVEDEAVKTEIFAELDKVVtDPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 499 EATTDEVVATAFEL-TRRLRKTGVLVHDATAFVVNRVL-------LRMmgeVQNSFDEGTDAHEADHAldPLALPMTPFT 570
Cdd:PRK07819 160 LVTSEATVARAEEFaSDVLGKQVVRAQDRSGFVVNALLvpyllsaIRM---VESGFATAEDIDKAMVL--GCAHPMGPLR 234
|
250 260 270
....*....|....*....|....*....|....*....
gi 738365679 571 LLAMVGIPVAQHVSESLSASFGAERFPVSANLQRLIDAG 609
Cdd:PRK07819 235 LSDLVGLDTVKAIADSMYEEFKEPLYAPPPLLLRMVEAG 273
|
|
| PRK06035 |
PRK06035 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
343-609 |
3.64e-47 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 180361 [Multi-domain] Cd Length: 291 Bit Score: 168.90 E-value: 3.64e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 343 EVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGV---RAQVEKMVSRGRLSAEDGEALAGLITADTDK 419
Cdd:PRK06035 2 DIKVIGVVGSGVMGQGIAQVFART-GYDVTIVDVSEEILKNAMELIesgPYGLRNLVEKGKMSEDEAKAIMARIRTSTSY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 420 AVYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTE 499
Cdd:PRK06035 81 ESLSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 500 ATTDEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGTDAHEADHALDPLA--LPMTPFTLLAMVGI 577
Cdd:PRK06035 161 LTSEETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGIATIKDIDEMCKLAfgFPMGPFELMDIIGI 240
|
250 260 270
....*....|....*....|....*....|..
gi 738365679 578 PVAQHVSESLSASFGAERFPVSANLQRLIDAG 609
Cdd:PRK06035 241 DTVYHIAEYLYEETGDPQFIPPNSLKQMVLNG 272
|
|
| PRK09260 |
PRK09260 |
3-hydroxyacyl-CoA dehydrogenase; |
344-610 |
3.13e-42 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 236434 [Multi-domain] Cd Length: 288 Bit Score: 154.95 E-value: 3.13e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 344 VRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDG-EALAGLITADTDKAVY 422
Cdd:PRK09260 1 IEKLVVVGAGVMGRGIAYVFAVS-GFQTTLVDIKQEQLESAQQEIASIFEQGVARGKLTEAARqAALARLSYSLDLKAAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 423 ADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATT 502
Cdd:PRK09260 80 ADADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 503 DEVVATAFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEGT-DAHEADHALD-PLALPMTPFTLLAMVGIPVA 580
Cdd:PRK09260 160 DETVQVAKEVAEQMGKETVVVNEFPGFVTSRISALVGNEAFYMLQEGVaTAEDIDKAIRlGLNFPMGPLELGDLVGLDTR 239
|
250 260 270
....*....|....*....|....*....|
gi 738365679 581 QHVSESLSASFGaERFPVSANLQRLIDAGK 610
Cdd:PRK09260 240 LNNLKYLHETLG-EKYRPAPLLEKYVKAGR 268
|
|
| PRK06130 |
PRK06130 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
343-613 |
6.31e-40 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 235707 [Multi-domain] Cd Length: 311 Bit Score: 149.15 E-value: 6.31e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 343 EVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGlagvRAQVEkmVSRGRLSAEDG-EALAGLITADTD-KA 420
Cdd:PRK06130 3 PIQNLAIIGAGTMGSGIAALFARK-GLQVVLIDVMEGALERA----RGVIE--RALGVYAPLGIaSAGMGRIRMEAGlAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 421 VYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEA 500
Cdd:PRK06130 76 AVSGADLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGDK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 501 TTDEVVATAFELTRRLRKTGVLVH-DATAFVVNRVLLRMMGEVQNSFDEG-TDAHEADHALD-----PLALpMTPFTLLA 573
Cdd:PRK06130 156 TSPQTVATTMALLRSIGKRPVLVKkDIPGFIANRIQHALAREAISLLEKGvASAEDIDEVVKwslgiRLAL-TGPLEQRD 234
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 738365679 574 MVGIPVAQHVSESLSASFgAERFPVSANLQRLIDAGKTAI 613
Cdd:PRK06130 235 MNGLDVHLAVASYLYQDL-ENRTTPSPLLEEKVEAGELGA 273
|
|
| PRK08293 |
PRK08293 |
3-hydroxyacyl-CoA dehydrogenase; |
343-613 |
1.28e-30 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 181359 [Multi-domain] Cd Length: 287 Bit Score: 121.97 E-value: 1.28e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 343 EVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDG--EALAGL-ITADTDK 419
Cdd:PRK08293 2 DIKNVTVAGAGVLGSQIAFQTAFH-GFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPaeAALNRItLTTDLAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 420 AVyADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTE 499
Cdd:PRK08293 81 AV-KDADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFAEATGRPEKFLALHFANEIWKNNTAEIMGHP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 500 ATTDEVVATAFELTRRLRKTGVLVHDATA-FVVNRVLLRMMGEVQNSF-DEGTDAHEADHA-LDPLALPMTPFTLLAMVG 576
Cdd:PRK08293 160 GTDPEVFDTVVAFAKAIGMVPIVLKKEQPgYILNSLLVPFLSAALALWaKGVADPETIDKTwMIATGAPMGPFGILDIVG 239
|
250 260 270
....*....|....*....|....*....|....*...
gi 738365679 577 IPVAQHVSESLSASFGAERF-PVSANLQRLIDAGKTAI 613
Cdd:PRK08293 240 LDTAYNITSNWAEATDDENAkKAAALLKEYIDKGKLGV 277
|
|
| PRK08269 |
PRK08269 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
359-610 |
1.98e-25 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181340 [Multi-domain] Cd Length: 314 Bit Score: 107.45 E-value: 1.98e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 359 LALVFARHlrvPVVMTDI---DAERVERGLAGVRAQVEK----MVSRGRLSAEDGEALAGLIT---ADTDKAVYADADIV 428
Cdd:PRK08269 7 LAFAFAGH---DVTLIDFkprDAAGWRALDAEARAEIERtlaaLVALGRIDAAQADAVLARIAvvaRDGAADALADADLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 429 IEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEATTDEVVAT 508
Cdd:PRK08269 84 FEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDATDPAVVDR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 509 AFELTRRLRKTGVLVHDATAFVVNRVLLRMMGEVQNSFDEG-TDAHEADHALDP-LALPMTPFTLLAMV---GIPVAQHV 583
Cdd:PRK08269 164 LAALLERIGKVPVVCGPSPGYIVPRIQALAMNEAARMVEEGvASAEDIDKAIRTgFGLRFAVLGLLEFIdwgGCDILYYA 243
|
250 260
....*....|....*....|....*..
gi 738365679 584 SESLSASFGAERFPVSANLQRLIDAGK 610
Cdd:PRK08269 244 SRYLAGEIGPDRFAPPAIVVRNMEEGR 270
|
|
| CaiD |
COG1024 |
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ... |
84-332 |
8.62e-21 |
|
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440647 [Multi-domain] Cd Length: 249 Bit Score: 92.15 E-value: 8.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGLTD-DVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGL 162
Cdd:COG1024 49 LTGAGKAFCAGADLKELAAAADpEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDAR-FGL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 163 PEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLknpldDNRMLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVAGDesva 241
Cdd:COG1024 128 PEVRLGLIPGGGGTQRLPRLVGLARAKELLL-----TGRRIDAEEALELGLVNRVVPdDELLAAALALAARLAAGP---- 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 242 aelaahrdrdvsdaawDRALAALERlqaarpgrhlparrhledLFTGARTRTRAESAQAEADALGTLLHSPEFRRTVYAF 321
Cdd:COG1024 199 ----------------PLALAATKR------------------ALNAALEAPLDEALELEAEAFAELFASEDAREGIAAF 244
|
250
....*....|.
gi 738365679 322 LglvqgrAKRP 332
Cdd:COG1024 245 L------EKRK 249
|
|
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
343-534 |
1.64e-20 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 92.80 E-value: 1.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 343 EVRKVGIVGAGLMAGQLALVFARHlRVPVVMTDIDAERVERGLAGVRAQVEKMVSRGRLSAEDGEALAGLITADTDKA-V 421
Cdd:PRK06129 1 PMGSVAIIGAGLIGRAWAIVFARA-GHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGEAPDAVLARIRVTDSLAdA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 422 YADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEIVRTEAT 501
Cdd:PRK06129 80 VADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVPAPWT 159
|
170 180 190
....*....|....*....|....*....|....
gi 738365679 502 TDEVVATAFELTRRLRKTGVLVH-DATAFVVNRV 534
Cdd:PRK06129 160 APATLARAEALYRAAGQSPVRLRrEIDGFVLNRL 193
|
|
| crotonase-like |
cd06558 |
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ... |
36-233 |
1.50e-19 |
|
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.
Pssm-ID: 119339 [Multi-domain] Cd Length: 195 Bit Score: 87.23 E-value: 1.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 36 GTLALLTLDNgqgPRRPATLGPATLLGLGRVLDEqaaRAAAGAIQALAVTGVEGTFAAGADLSLIAGLTDD--VGRDLAL 113
Cdd:cd06558 7 GGVATITLNR---PEKRNALSLEMLDELAAALDE---AEADPDVRVVVLTGAGKAFCAGADLKELAALSDAgeEARAFIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 114 LGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVL 193
Cdd:cd06558 81 ELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAK-FGLPEVKLGLVPGGGGTQRLPRLVGPARARELLL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 738365679 194 KnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELAAAL 233
Cdd:cd06558 160 T-----GRRISAEEALELGLVDEVVPdEELLAAALELARRL 195
|
|
| PRK07531 |
PRK07531 |
carnitine 3-dehydrogenase; |
346-535 |
6.22e-17 |
|
carnitine 3-dehydrogenase;
Pssm-ID: 236044 [Multi-domain] Cd Length: 495 Bit Score: 84.40 E-value: 6.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 346 KVGIVGAGLMAGQLAlvfARHL----RVPVVMTDIDAER-VERGLAGVRAQVEKMVS-----RGRLSaedgealaglITA 415
Cdd:PRK07531 6 KAACIGGGVIGGGWA---ARFLlagiDVAVFDPHPEAERiIGEVLANAERAYAMLTDaplppEGRLT----------FCA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 416 DTDKAVyADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFNPVAVMPLVEI 495
Cdd:PRK07531 73 SLAEAV-AGADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVEL 151
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 738365679 496 VRTEATTDEVVATAFELTRRLRKTGV-LVHDATAFVVNRVL 535
Cdd:PRK07531 152 VGGGKTSPETIRRAKEILREIGMKPVhIAKEIDAFVGDRLL 192
|
|
| PRK05809 |
PRK05809 |
short-chain-enoyl-CoA hydratase; |
36-235 |
2.22e-15 |
|
short-chain-enoyl-CoA hydratase;
Pssm-ID: 180270 [Multi-domain] Cd Length: 260 Bit Score: 76.71 E-value: 2.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 36 GTLALLTLDNgqgPRRPATLGPATLLGLGRVLDEqaaRAAAGAIQALAVTGV-EGTFAAGADLSLIAGLTDDVGRDLALL 114
Cdd:PRK05809 12 GHIAVVTINR---PKALNALNSETLKELDTVLDD---IENDDNVYAVILTGAgEKAFVAGADISEMKDLNEEEGRKFGLL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 115 GHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLK 194
Cdd:PRK05809 86 GNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAK-FGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYT 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 738365679 195 nplddNRMLDARAAHGLGLMDRIVEGD-LLDAGLELAAALVA 235
Cdd:PRK05809 165 -----GDMINAEEALRIGLVNKVVEPEkLMEEAKALANKIAA 201
|
|
| PRK05862 |
PRK05862 |
enoyl-CoA hydratase; Provisional |
84-236 |
1.81e-11 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180295 [Multi-domain] Cd Length: 257 Bit Score: 65.06 E-value: 1.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGLT--DDVGRDLAllghAVYDRLAALEIPTVALVnGLALGGGLELALAAGHRVVAADAKGFG 161
Cdd:PRK05862 54 ITGSEKAFAAGADIKEMADLSfmDVYKGDYI----TNWEKVARIRKPVIAAV-AGYALGGGCELAMMCDIIIAADTAKFG 128
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738365679 162 LPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGD-LLDAGLElAAALVAG 236
Cdd:PRK05862 129 QPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLT-----GRMMDAAEAERAGLVSRVVPADkLLDEALA-AATTIAS 198
|
|
| ECH_1 |
pfam00378 |
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ... |
85-255 |
2.79e-11 |
|
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.
Pssm-ID: 395302 [Multi-domain] Cd Length: 251 Bit Score: 64.30 E-value: 2.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADLSLIAGLTddvGRDLALLGHAVYD---RLAALEIPTVALVNGLALGGGLELALAAGHrVVAADAKGFG 161
Cdd:pfam00378 47 TGGDKAFCAGADLKEMYGEG---PAHQALYRENVLDlwtLLYTCPKPVIAAVNGYAIGGGCELALACDI-IIAADNASFG 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 162 LPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLknpldDNRMLDARAAHGLGLMDRIV-EGDLLDAGLELAAALVAGDESV 240
Cdd:pfam00378 123 LNETKLGIIPGAGGTDRLPRIIGHSKAMEMLL-----LGRRISAQEALKWGLVDKVVpEDQLLDEARELAEKLAEKSPAA 197
|
170
....*....|....*
gi 738365679 241 AAELAAHRDRDVSDA 255
Cdd:pfam00378 198 LAQLKKALNAKLEDA 212
|
|
| PRK03580 |
PRK03580 |
crotonobetainyl-CoA hydratase; |
152-290 |
3.12e-11 |
|
crotonobetainyl-CoA hydratase;
Pssm-ID: 179599 [Multi-domain] Cd Length: 261 Bit Score: 64.33 E-value: 3.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 152 VVAADAKGFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGD-LLDAGLELA 230
Cdd:PRK03580 119 IVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMT-----GRRMDAEEALRWGIVNRVVPQAeLMDRARELA 193
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 231 AALVAGdesvaAELAAHRDRDVSDAAWDRALAALERLQAARPGRHLPARRHLEDLFTGAR 290
Cdd:PRK03580 194 QQLVNS-----APLAIAALKEIYRETSEMPVEEAYRYIRSGVLKHYPSVLHSEDALEGPR 248
|
|
| PRK08252 |
PRK08252 |
crotonase/enoyl-CoA hydratase family protein; |
152-235 |
4.28e-11 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181325 [Multi-domain] Cd Length: 254 Bit Score: 63.86 E-value: 4.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 152 VVAADAKGFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELA 230
Cdd:PRK08252 116 IVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALT-----GDMLTAERAHELGLVNRLTEpGQALDAALELA 190
|
....*
gi 738365679 231 AALVA 235
Cdd:PRK08252 191 ERIAA 195
|
|
| PRK07066 |
PRK07066 |
L-carnitine dehydrogenase; |
406-549 |
4.71e-11 |
|
L-carnitine dehydrogenase;
Pssm-ID: 168796 [Multi-domain] Cd Length: 321 Bit Score: 64.86 E-value: 4.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 406 GEALAGLITADTDKAVYADADIVIEAVFEELEVKRTVFRELEGIVREDAILMTNTSSLSVAAMAEVLEHPERLVGFHFFN 485
Cdd:PRK07066 65 GASPARLRFVATIEACVADADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFN 144
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738365679 486 PVAVMPLVEIVRTEATTDEVVATAFELTRRLRKTGVLVH-DATAFVVNRVLLRMMGEVQNSFDEG 549
Cdd:PRK07066 145 PVYLLPLVEVLGGERTAPEAVDAAMGIYRALGMRPLHVRkEVPGFIADRLLEALWREALHLVNEG 209
|
|
| PRK07657 |
PRK07657 |
enoyl-CoA hydratase; Provisional |
37-235 |
3.24e-10 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 181069 [Multi-domain] Cd Length: 260 Bit Score: 61.29 E-value: 3.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 37 TLALLTLDNgqgPRRPATLGPATLLGLGRVLDEqaaRAAAGAIQALAVTGV-EGTFAAGADLSLIAGLTDD-VGRDLALL 114
Cdd:PRK07657 13 HVVKITLNR---PRAANALSLALLEELQNILTQ---INEEANVRVVILTGAgEKAFCAGADLKERAGMNEEqVRHAVSLI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 115 GHAVyDRLAALEIPTVALVNGLALGGGLELALAAGHRvVAADAKGFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLK 194
Cdd:PRK07657 87 RTTM-EMVEQLPQPVIAAINGIALGGGLELALACDFR-IAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYT 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 738365679 195 nplddNRMLDARAAHGLGLMDRIVEGD-LLDAGLELAAALVA 235
Cdd:PRK07657 165 -----GRRISAQEAKEIGLVEFVVPAHlLEEKAIEIAEKIAS 201
|
|
| PRK06688 |
PRK06688 |
enoyl-CoA hydratase; Provisional |
85-322 |
5.46e-10 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235852 [Multi-domain] Cd Length: 259 Bit Score: 60.65 E-value: 5.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADLSLIAGLTDDvGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPE 164
Cdd:PRK06688 56 TGAGRAFSAGGDIKDFPKAPPK-PPDELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAK-FSLPF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 165 VRLGLIPGWSGVWRVPHLIGPEAAVDVVLKNPlddnrMLDARAAHGLGLMDRIV-EGDLLDAGLELAAALVAGDesvaae 243
Cdd:PRK06688 134 AKLGLCPDAGGSALLPRLIGRARAAEMLLLGE-----PLSAEEALRIGLVNRVVpAAELDAEADAQAAKLAAGP------ 202
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738365679 244 laahrdrdvsdaawdralaalerlqaarpgrhLPARRHLEDLFTGARTRTRAESAQAEADALGTLLHSPEFRRTVYAFL 322
Cdd:PRK06688 203 --------------------------------ASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFI 249
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
529-610 |
2.66e-09 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 54.92 E-value: 2.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 529 FVVNRVLLRMMGEVQNSFDEGT-DAHEADHAL-DPLALPMTPFTLLAMVGIPVAQHVSESLSASFGAERFPVSANLQRLI 606
Cdd:pfam00725 2 FVVNRLLAPYLNEAIRLVEEGVaTPEDIDAAMrLGLGLPMGPFELSDLVGLDVGYHILEVLAEEFGDRAYRPPPLLEKLV 81
|
....
gi 738365679 607 DAGK 610
Cdd:pfam00725 82 EAGR 85
|
|
| PRK07658 |
PRK07658 |
enoyl-CoA hydratase; Provisional |
91-231 |
3.02e-09 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 181070 [Multi-domain] Cd Length: 257 Bit Score: 58.49 E-value: 3.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 91 FAAGADLSLIAGLTD-DVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVRLGL 169
Cdd:PRK07658 58 FSAGADIKEFTSVTEaEQATELAQLGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAK-LGLPELNLGL 136
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 738365679 170 IPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIV-EGDLLDAGLELAA 231
Cdd:PRK07658 137 IPGFAGTQRLPRYVGKAKALEMMLT-----SEPITGAEALKWGLVNGVFpEETLLDDAKKLAK 194
|
|
| PRK06494 |
PRK06494 |
enoyl-CoA hydratase; Provisional |
152-290 |
8.05e-08 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180591 [Multi-domain] Cd Length: 259 Bit Score: 54.28 E-value: 8.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 152 VVAADAKGFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIV-EGDLLDAGLELA 230
Cdd:PRK06494 119 IVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILT-----GRRVTAREGLELGFVNEVVpAGELLAAAERWA 193
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738365679 231 AALVAGDE-SV-AAELAAHRDRDVSdaawdralaaLERLQAARpgRHLPA---RRHLEDLFTGAR 290
Cdd:PRK06494 194 DDILACSPlSIrASKQAVYRGLEVS----------LEEAITAQ--RDYPAveaRRASQDYIEGPK 246
|
|
| PLN02600 |
PLN02600 |
enoyl-CoA hydratase |
87-230 |
8.61e-08 |
|
enoyl-CoA hydratase
Pssm-ID: 178210 [Multi-domain] Cd Length: 251 Bit Score: 54.04 E-value: 8.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 87 VEGTFAAGADLSLIAGLTDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVR 166
Cdd:PLN02600 49 VPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAV-FGLPETG 127
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738365679 167 LGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELA 230
Cdd:PLN02600 128 LAIIPGAGGTQRLPRLVGRSRAKELIFT-----GRRIGAREAASMGLVNYCVPaGEAYEKALELA 187
|
|
| PRK05995 |
PRK05995 |
enoyl-CoA hydratase; Provisional |
152-263 |
9.57e-08 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235664 [Multi-domain] Cd Length: 262 Bit Score: 53.78 E-value: 9.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 152 VVAADAKGFGLPEVRLGLIPGWSGVWrVPHLIGPEAAvdvvlknplddNRM------LDARAAHGLGLMDRIVEGDLLDA 225
Cdd:PRK05995 124 AVAADHAVFCLSEVRLGLIPATISPY-VIRAMGERAA-----------RRYfltaerFDAAEALRLGLVHEVVPAEALDA 191
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 738365679 226 GL-ELAAALVAGdeSVAAELAAHRD-RDVSDAAWDRALAA 263
Cdd:PRK05995 192 KVdELLAALVAN--SPQAVRAGKRLvRDVAGRPIDAALIA 229
|
|
| PRK07468 |
PRK07468 |
crotonase/enoyl-CoA hydratase family protein; |
152-264 |
6.31e-07 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 180987 [Multi-domain] Cd Length: 262 Bit Score: 51.60 E-value: 6.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 152 VVAADAKGFGLPEVRLGLIPGWSGVWRVPHlIGPEAAVDVVLknpldDNRMLDARAAHGLGLMDRIVEGDLLDAGLE--L 229
Cdd:PRK07468 125 AIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFM-----SARLFDAEEAVRLGLLSRVVPAERLDAAVEaeV 198
|
90 100 110
....*....|....*....|....*....|....*..
gi 738365679 230 AAALVAGDESVAA--ELAAHRDRDVSDAAWDRALAAL 264
Cdd:PRK07468 199 TPYLSCAPGAVAAakALVRALGAPIDEAVIDATIEAL 235
|
|
| PRK06127 |
PRK06127 |
enoyl-CoA hydratase; Provisional |
88-270 |
1.08e-06 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235705 Cd Length: 269 Bit Score: 50.86 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 88 EGTFAAGADLSLIAGLTDDVGrdlallGHAVYDR--------LAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKg 159
Cdd:PRK06127 66 EKAFVSGADISQFEESRSDAE------AVAAYEQaveaaqaaLADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSR- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 160 FGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGDLLDAGLELAAALVAGDES 239
Cdd:PRK06127 139 FGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYT-----ARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAP 213
|
170 180 190
....*....|....*....|....*....|.
gi 738365679 240 VAAELAAHRDRDVSDAAWDRALAALERLQAA 270
Cdd:PRK06127 214 LTLRAAKRAIAELLKDEPERDMAACQALVAA 244
|
|
| PRK05870 |
PRK05870 |
enoyl-CoA hydratase; Provisional |
84-241 |
1.28e-06 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180298 Cd Length: 249 Bit Score: 50.49 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLS-LIAGLTDDVGRDLallgHAVYD---RLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKg 159
Cdd:PRK05870 53 VTGAGKAFCAGADLTaLGAAPGRPAEDGL----RRIYDgflAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKAL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 160 FGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLknpldDNRMLDARAAHGLGLMDRIVEgDLLDAGLELAAALVAGDES 239
Cdd:PRK05870 128 FDARFQKLGLHPGGGATWMLQRAVGPQVARAALL-----FGMRFDAEAAVRHGLALMVAD-DPVAAALELAAGPAAAPRE 201
|
..
gi 738365679 240 VA 241
Cdd:PRK05870 202 LV 203
|
|
| PRK05980 |
PRK05980 |
crotonase/enoyl-CoA hydratase family protein; |
28-246 |
2.33e-06 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 180335 [Multi-domain] Cd Length: 260 Bit Score: 49.76 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 28 DHALPDGAGTLALLTLDngqgprRPATLGPATLLGLGRVLDEQAARAAAGAIQALAVTGV-EGTFAAGADlslIAGLTDD 106
Cdd:PRK05980 3 DTVLIEIRDGIALLTLN------RPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAgDRAFSAGAD---IHEFSAS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 107 VG-------RDLALLGHAVYDRLAALEIPTVALVNGLALgGGLELALAAGHRVVAADAKGFGLPEVRLGLIPGWSGVWRV 179
Cdd:PRK05980 74 VAagadvalRDFVRRGQAMTARLEAFPKPVIAAVNGLAF-GGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 180 PHLIGPEAAVDVVLK-NPLDDNRMLDaraahgLGLMDRIV-EGDLLDAGLELAAALVA-GDESVAAELAA 246
Cdd:PRK05980 153 PRLAGRKRALELLLTgDAFSAERALE------IGLVNAVVpHEELLPAARALARRIIRhSPVAVAAILTA 216
|
|
| PRK05869 |
PRK05869 |
enoyl-CoA hydratase; Validated |
91-221 |
1.35e-05 |
|
enoyl-CoA hydratase; Validated
Pssm-ID: 235632 [Multi-domain] Cd Length: 222 Bit Score: 46.76 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 91 FAAGADLSLIAGLTDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVRLGLI 170
Cdd:PRK05869 64 FSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVK-FGATEILAGLA 142
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 738365679 171 PGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGD 221
Cdd:PRK05869 143 PSGDGMARLTRAAGPSRAKELVFS-----GRFFDAEEALALGLIDEMVAPD 188
|
|
| PRK08138 |
PRK08138 |
enoyl-CoA hydratase; Provisional |
85-266 |
2.06e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236162 [Multi-domain] Cd Length: 261 Bit Score: 46.97 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADL-SLI-AGLTDDVGRDLallgHAVYDRLAALEIPTVALVNGLALGGGLELALAAGhRVVAADAKGFGL 162
Cdd:PRK08138 59 TGGEKVFAAGADIkEFAtAGAIEMYLRHT----ERYWEAIAQCPKPVIAAVNGYALGGGCELAMHAD-IIVAGESASFGQ 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 163 PEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVAgdesvA 241
Cdd:PRK08138 134 PEIKVGLMPGAGGTQRLVRAVGKFKAMRMALT-----GCMVPAPEALAIGLVSEVVEdEQTLPRALELAREIAR-----M 203
|
170 180
....*....|....*....|....*....
gi 738365679 242 AELAAHRDRDV----SDAAWDRALaALER 266
Cdd:PRK08138 204 PPLALAQIKEVvlagADAPLDAAL-ALER 231
|
|
| PRK08260 |
PRK08260 |
enoyl-CoA hydratase; Provisional |
84-245 |
2.43e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236206 [Multi-domain] Cd Length: 296 Bit Score: 46.92 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLS--------------------LIAGLTDDVGRDLallGHAVYDRLAALEIPTVALVNGLALGGGLE 143
Cdd:PRK08260 54 VTGAGRAFCAGADLSaggntfdldaprtpveadeeDRADPSDDGVRDG---GGRVTLRIFDSLKPVIAAVNGPAVGVGAT 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 144 LALAAGHRVVAADAKgFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGD-L 222
Cdd:PRK08260 131 MTLAMDIRLASTAAR-FGFVFGRRGIVPEAASSWFLPRLVGLQTALEWVYS-----GRVFDAQEALDGGLVRSVHPPDeL 204
|
170 180
....*....|....*....|...
gi 738365679 223 LDAGLELAAALVAGDESVAAELA 245
Cdd:PRK08260 205 LPAARALAREIADNTSPVSVALT 227
|
|
| PRK07799 |
PRK07799 |
crotonase/enoyl-CoA hydratase family protein; |
85-249 |
2.92e-05 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181122 [Multi-domain] Cd Length: 263 Bit Score: 46.25 E-value: 2.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADL----------SLIAGLTDDVGRDLALLGHAVYDRL-AALEIPTVAlvnglalgGGLELALAAGHRVV 153
Cdd:PRK07799 56 TGAGGAFCAGMDLkaatkkppgdSFKDGSYDPSRIDALLKGRRLTKPLiAAVEGPAIA--------GGTEILQGTDIRVA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 154 AADAKgFGLPEVRLGLIP-GWSGVwRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIV-EGDLLDAGLELAA 231
Cdd:PRK07799 128 GESAK-FGISEAKWSLFPmGGSAV-RLVRQIPYTVACDLLLT-----GRHITAAEAKEIGLIGHVVpDGQALDKALELAE 200
|
170
....*....|....*....
gi 738365679 232 ALVA-GDESVAAELAAHRD 249
Cdd:PRK07799 201 LINAnGPLAVQAILRTIRE 219
|
|
| PRK09674 |
PRK09674 |
enoyl-CoA hydratase-isomerase; Provisional |
84-245 |
3.21e-05 |
|
enoyl-CoA hydratase-isomerase; Provisional
Pssm-ID: 182026 [Multi-domain] Cd Length: 255 Bit Score: 46.30 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAglTDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGhRVVAADAKGFGLP 163
Cdd:PRK09674 52 ITGNARFFAAGADLNEMA--EKDLAATLNDPRPQLWQRLQAFNKPLIAAVNGYALGAGCELALLCD-IVIAGENARFGLP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 164 EVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGDLLDAGLELAAALVAGDESVAAE 243
Cdd:PRK09674 129 EITLGIMPGAGGTQRLIRSVGKSLASQMVLT-----GESITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALR 203
|
..
gi 738365679 244 LA 245
Cdd:PRK09674 204 AA 205
|
|
| PRK09245 |
PRK09245 |
crotonase/enoyl-CoA hydratase family protein; |
122-235 |
4.85e-05 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181723 Cd Length: 266 Bit Score: 45.73 E-value: 4.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 122 LAALEIPTVALVNGLALGGGLELALAAGHRvVAADAKGFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNR 201
Cdd:PRK09245 99 LYNLEVPVIAAVNGPAIGAGCDLACMCDIR-IASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFT-----GD 172
|
90 100 110
....*....|....*....|....*....|....*
gi 738365679 202 MLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVA 235
Cdd:PRK09245 173 AIDAATALEWGLVSRVVPaDQLLPAARALAERIAA 207
|
|
| PRK05981 |
PRK05981 |
enoyl-CoA hydratase/isomerase; |
33-268 |
2.18e-04 |
|
enoyl-CoA hydratase/isomerase;
Pssm-ID: 235661 Cd Length: 266 Bit Score: 43.57 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 33 DGAGTLALLTLDNgqgprrPATL---GPATLLGLGRVLDEqaARAAAGAIQALAVTGVEGTFAAGADLS------LIAGL 103
Cdd:PRK05981 9 DFDGGVAILTLDH------PEVMnavSIDMLGGLAEALDA--IEDGKAEVRCLVLTGAGRGFCTGANLQgrgsggRESDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 104 TDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGhRVVAADAKGFGLPEVRLGLIPGWSGVWRVPHLI 183
Cdd:PRK05981 81 GGDAGAALETAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGD-LILCARSAYFLQAFRRIGLVPDGGSTWLLPRLV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 184 GPEAAVDVVLknpLDDNrmLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVAGDesvAAELAAHRDR--DVSDAAWDRA 260
Cdd:PRK05981 160 GKARAMELSL---LGEK--LPAETALQWGLVNRVVDdAELMAEAMKLAHELANGP---TVALGLIRKLywDSPENDFEEQ 231
|
....*...
gi 738365679 261 LAALERLQ 268
Cdd:PRK05981 232 LNLEREAQ 239
|
|
| PRK06143 |
PRK06143 |
enoyl-CoA hydratase; Provisional |
88-236 |
4.18e-04 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180423 Cd Length: 256 Bit Score: 42.71 E-value: 4.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 88 EGTFAAGADLSLIAGLTDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVRL 167
Cdd:PRK06143 62 EKAFIGGADIKEMATLDQASAEAFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQ-FGMPEVRV 140
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738365679 168 GlIPGWSGVWRVPHLIGPEAAVDVVLKNPLddnrmLDARAAHGLGLMDRIVEGDLLDAGLELAAALVAG 236
Cdd:PRK06143 141 G-IPSVIHAALLPRLIGWARTRWLLLTGET-----IDAAQALAWGLVDRVVPLAELDAAVERLAASLAG 203
|
|
| PRK06210 |
PRK06210 |
enoyl-CoA hydratase; Provisional |
85-338 |
6.20e-04 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180472 Cd Length: 272 Bit Score: 42.38 E-value: 6.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADLSLIAGLTDDVGRDLALLGHAVYDR----------LAALEIPTVALVNGLALGGGLELALAAGHRVVA 154
Cdd:PRK06210 57 TGAGRGFCAGADMGELQTIDPSDGRRDTDVRPFVGNRrpdyqtryhfLTALRKPVIAAINGACAGIGLTHALMCDVRFAA 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 155 ADAKgFGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGD-LLDAGLELAaal 233
Cdd:PRK06210 137 DGAK-FTTAFARRGLIAEHGISWILPRLVGHANALDLLLS-----ARTFYAEEALRLGLVNRVVPPDeLMERTLAYA--- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 234 vagdesvaaelaahrdRDVSDAAWDRALAALERLQAARPgrhlparrhledlftgarTRTRAE-SAQAEADALGTLLhSP 312
Cdd:PRK06210 208 ----------------EDLARNVSPASMAVIKRQLYEDA------------------FQTLAEaTARANREMHESLQ-RP 252
|
250 260
....*....|....*....|....*.
gi 738365679 313 EFRRTVYAFLglvqgrAKRPAGDPGR 338
Cdd:PRK06210 253 DFIEGVASFL------EKRPPRFPGL 272
|
|
| PRK06190 |
PRK06190 |
enoyl-CoA hydratase; Provisional |
84-280 |
8.40e-04 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235733 Cd Length: 258 Bit Score: 41.88 E-value: 8.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGLTDDVGRDLAllGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLP 163
Cdd:PRK06190 54 LTGADPAFCAGLDLKELGGDGSAYGAQDA--LPNPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERAR-FADT 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 164 EVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKNPLddnrmLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVAGDESVAA 242
Cdd:PRK06190 131 HARVGILPGWGLSVRLPQKVGIGRARRMSLTGDF-----LDAADALRAGLVTEVVPhDELLPRARRLAASIAGNNPAAVR 205
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 738365679 243 ELAAHRDR----DVSDAAWDRALAALERLQAARPGrHLPARR 280
Cdd:PRK06190 206 ALKASYDDgaaaQTGDALALEAEAARAHNRSVSPD-GIAARR 246
|
|
| PRK08150 |
PRK08150 |
crotonase/enoyl-CoA hydratase family protein; |
91-231 |
1.45e-03 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181254 Cd Length: 255 Bit Score: 41.16 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 91 FAAGADLSLIAGLTDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLElALAAGHRVVAADAKGFGLPEVRLGLI 170
Cdd:PRK08150 57 FCAGLDLSELRERDAGEGMHHSRRWHRVFDKIQYGRVPVIAALHGAVVGGGLE-LASAAHIRVADESTYFALPEGQRGIF 135
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738365679 171 PGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELAA 231
Cdd:PRK08150 136 VGGGGSVRVPRLIGVARMTDMMLT-----GRVYDAQEGERLGLAQYLVPaGEALDKAMELAR 192
|
|
| PRK06144 |
PRK06144 |
enoyl-CoA hydratase; Provisional |
91-235 |
1.60e-03 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180424 [Multi-domain] Cd Length: 262 Bit Score: 41.13 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 91 FAAGADLSLIAGL-TDDVGRDLALLGHAVYDRLAALEIPTVALVNGLALGGGLELALAAGHRVVAADAKgFGLPEVR-LG 168
Cdd:PRK06144 66 FVAGTDIAQFRAFsTAEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSAR-FGFPIARtLG 144
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 738365679 169 LIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGDLLDAGLELAAALVA 235
Cdd:PRK06144 145 NCLSMSNLARLVALLGAARVKDMLFT-----ARLLEAEEALAAGLVNEVVEDAALDARADALAELLA 206
|
|
| PRK08259 |
PRK08259 |
crotonase/enoyl-CoA hydratase family protein; |
85-235 |
3.42e-03 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 236205 Cd Length: 254 Bit Score: 39.88 E-value: 3.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 85 TGVEGTFAAGADLSLIAgltDDVGRDLALLGHAVY--DRLAaLEIPTVALVNGLALGGGLELALAAGHRVVAADA----- 157
Cdd:PRK08259 54 WGAGGTFCAGADLKAVG---TGRGNRLHPSGDGPMgpSRMR-LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAvfgvf 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 158 -KGFGLPevrlgLIPGwsGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVE-GDLLDAGLELAAALVA 235
Cdd:PRK08259 130 cRRWGVP-----LIDG--GTVRLPRLIGHSRAMDLILT-----GRPVDADEALAIGLANRVVPkGQARAAAEELAAELAA 197
|
|
| TyrA |
COG0287 |
Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is ... |
345-482 |
4.67e-03 |
|
Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 440056 [Multi-domain] Cd Length: 278 Bit Score: 39.72 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 345 RKVGIVGAGLMAGQLALVF-ARHLRVPVVMTDIDAERVERGLAgvraqvEKMVSRgrlsaedgealaglITADTDKAVyA 423
Cdd:COG0287 2 MRIAIIGLGLIGGSLALALkRAGLAHEVVGVDRSPETLERALE------LGVIDR--------------AATDLEEAV-A 60
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738365679 424 DADIVIEAVfeELEVKRTVFRELEGIVREDAILmTNTSS---LSVAAMAEVLEHPERLVGFH 482
Cdd:COG0287 61 DADLVVLAV--PVGATIEVLAELAPHLKPGAIV-TDVGSvkgAVVEAAEALLPDGVRFVGGH 119
|
|
| PRK09120 |
PRK09120 |
p-hydroxycinnamoyl CoA hydratase/lyase; Validated |
84-284 |
9.90e-03 |
|
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
Pssm-ID: 236383 Cd Length: 275 Bit Score: 38.45 E-value: 9.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 84 VTGVEGTFAAGADLSLIAGLTDDVGRDLALLGHAV----YDRLAALEIPTVALVNGLALGGGLELALAAGhRVVAADAKG 159
Cdd:PRK09120 58 LTGAGDAWSAGMDLKEYFRETDAQPEILQERIRREaygwWRRLRWYQKPTIAMVNGWCFGGGFSPLVACD-LAIAADEAQ 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738365679 160 FGLPEVRLGLIPGWSGVWRVPHLIGPEAAVDVVLKnplddNRMLDARAAHGLGLMDRIVEGDLLDAG-LELAAALVAGDE 238
Cdd:PRK09120 137 FGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMT-----GETFTGRKAAEMGLVNESVPLAQLRARtRELAAKLLEKNP 211
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 738365679 239 SV--AAELAAHRDRDVS-DAAWDRALAALERLQAARP--GRHLPARRHLED 284
Cdd:PRK09120 212 VVlrAAKDGFKRVRELTwDQAEDYLYAKLEQANSLDPegGREEGLKQFLDD 262
|
|
| |
