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Conserved domains on  [gi|734902759|ref|WP_034133835|]
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MULTISPECIES: alpha/beta hydrolase [Pseudomonas]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10785415)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  19508187|12369917|37582413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YpfH COG0400
Predicted esterase [General function prediction only];
37-238 6.40e-60

Predicted esterase [General function prediction only];


:

Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 187.42  E-value: 6.40e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  37 DARNQPLVIFLHGFGSNEEDLFGIKDALPS-TWTYLSVRAPLPVAPQGYRWFTkTDEPEYNGETDELFSSARLIKDFVLK 115
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALpGAAVLAPRAPVPEGPGGRAWFD-LSFLEGREDEEGLAAAAEALAAFIDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 116 ATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRsALKPDAAMGKLAIFIGHGTLDQALPFSSA 195
Cdd:COG0400   80 LEARYGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEA-LPAPEAALAGTPVFLAHGTQDPVIPVERA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 734902759 196 TQANKVLAGLGLKPEFHEYPgMNHTISEAEIQDLKAWLEKSLK 238
Cdd:COG0400  159 REAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
 
Name Accession Description Interval E-value
YpfH COG0400
Predicted esterase [General function prediction only];
37-238 6.40e-60

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 187.42  E-value: 6.40e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  37 DARNQPLVIFLHGFGSNEEDLFGIKDALPS-TWTYLSVRAPLPVAPQGYRWFTkTDEPEYNGETDELFSSARLIKDFVLK 115
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALpGAAVLAPRAPVPEGPGGRAWFD-LSFLEGREDEEGLAAAAEALAAFIDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 116 ATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRsALKPDAAMGKLAIFIGHGTLDQALPFSSA 195
Cdd:COG0400   80 LEARYGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEA-LPAPEAALAGTPVFLAHGTQDPVIPVERA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 734902759 196 TQANKVLAGLGLKPEFHEYPgMNHTISEAEIQDLKAWLEKSLK 238
Cdd:COG0400  159 REAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 36-237 6.72e-29

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 108.23  E-value: 6.72e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   36 GDARNQPLVIFLHGFGSNEE---DLFGIKDALPSTwTYLSVRAP-LPV-APQGYR---WFTKTDEPEYNGETDELFS-SA 106
Cdd:pfam02230   9 PRDPAQATVIFLHGLGDSGHgwaDAAKTEAPLPNI-KFIFPHGPeIPVtLNGGMRmpaWFDLVGLSPNAKEDEAGIKnSA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  107 RLIKDFVlKATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRSALKPDAAMGKLAIFIGHGTL 186
Cdd:pfam02230  88 ETIEELI-DAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTKKTPIFLIHGEE 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 734902759  187 DQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTISEAEIQDLKAWLEKSL 237
Cdd:pfam02230 167 DPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
PRK11460 PRK11460
putative hydrolase; Provisional
 29-227 3.97e-13

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 66.22  E-value: 3.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  29 SYLEQTQGDARNQPLVIFLHGFGSNEEDLFGI----KDALPSTwTYLSVRAPLPVA-PQGYRWFTKTDEPEYNgetdELF 103
Cdd:PRK11460   4 DHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIgswfAPAFPDA-LVVSVGGPEPSGnGAGRQWFSVQGITEDN----RQA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 104 SSARLIKDFVlkATAKYHTQSDRVF-----LVGFSQGAIMSYEVALREPELVRGIAALSGsvlpvlRSALKPDAAMGKLA 178
Cdd:PRK11460  79 RVAAIMPTFI--ETVRYWQQQSGVGasataLIGFSQGAIMALEAVKAEPGLAGRVIAFSG------RYASLPETAPTATT 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 734902759 179 IFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTISEAEIQ 227
Cdd:PRK11460 151 IHLIHGGEDPVIDVAHAVAAQEALISLGGDVTLDIVEDLGHAIDPRLMQ 199
 
Name Accession Description Interval E-value
YpfH COG0400
Predicted esterase [General function prediction only];
37-238 6.40e-60

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 187.42  E-value: 6.40e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  37 DARNQPLVIFLHGFGSNEEDLFGIKDALPS-TWTYLSVRAPLPVAPQGYRWFTkTDEPEYNGETDELFSSARLIKDFVLK 115
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALpGAAVLAPRAPVPEGPGGRAWFD-LSFLEGREDEEGLAAAAEALAAFIDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 116 ATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRsALKPDAAMGKLAIFIGHGTLDQALPFSSA 195
Cdd:COG0400   80 LEARYGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEA-LPAPEAALAGTPVFLAHGTQDPVIPVERA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 734902759 196 TQANKVLAGLGLKPEFHEYPgMNHTISEAEIQDLKAWLEKSLK 238
Cdd:COG0400  159 REAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 36-237 6.72e-29

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 108.23  E-value: 6.72e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   36 GDARNQPLVIFLHGFGSNEE---DLFGIKDALPSTwTYLSVRAP-LPV-APQGYR---WFTKTDEPEYNGETDELFS-SA 106
Cdd:pfam02230   9 PRDPAQATVIFLHGLGDSGHgwaDAAKTEAPLPNI-KFIFPHGPeIPVtLNGGMRmpaWFDLVGLSPNAKEDEAGIKnSA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  107 RLIKDFVlKATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRSALKPDAAMGKLAIFIGHGTL 186
Cdd:pfam02230  88 ETIEELI-DAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTKKTPIFLIHGEE 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 734902759  187 DQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTISEAEIQDLKAWLEKSL 237
Cdd:pfam02230 167 DPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
COG4099 COG4099
Predicted peptidase [General function prediction only];
1-233 7.18e-23

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 92.72  E-value: 7.18e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   1 MLKQLAFALALVAGA-----AHADSGLHTDLPLSYLE---QTQGDARNQPLVIFLHGFGSNEEDLFGIKDALPSTWTYLS 72
Cdd:COG4099    1 MKKLLLLLLLLGCAAqdgfeARTFTDPSDGDTLPYRLylpKGYDPGKKYPLVLFLHGAGERGTDNEKQLTHGAPKFINPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  73 VRAPLP---VAPQ--GYRWFTKTDEPEyngetdelfssarLIKDFVLKATAKYHTQSDRVFLVGFSQGAIMSYEVALREP 147
Cdd:COG4099   81 NQAKFPaivLAPQcpEDDYWSDTKALD-------------AVLALLDDLIAEYRIDPDRIYLTGLSMGGYGTWDLAARYP 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 148 ELVRGIAALSGSVLPVLRSALKpdaamgKLAIFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNH-TISEA-E 225
Cdd:COG4099  148 DLFAAAVPICGGGDPANAANLK------KVPVWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHnSWDPAyA 221


                 ....*...
gi 734902759 226 IQDLKAWL 233
Cdd:COG4099  222 NPDLYDWL 229
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 5-198 9.56e-21

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 88.14  E-value: 9.56e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   5 LAFALALVAGAAHADSGLHT----DLPLSYLE---QTQGDARNQPLVIFLHGFGSNEEDLF---GIkDALPSTWTYLsVr 74
Cdd:COG3509   10 LAALLALLPAAAAAGDFERTftvgGGTRTYRLyvpAGYDGGAPLPLVVALHGCGGSAADFAagtGL-NALADREGFI-V- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  75 aplpVAPQGYR--------WFTKTDEPEYNGEtdelfssARLIKDFVLKATAKYHTQSDRVFLVGFSQGAIMSYEVALRE 146
Cdd:COG3509   87 ----VYPEGTGrapgrcwnWFDGRDQRRGRDD-------VAFIAALVDDLAARYGIDPKRVYVTGLSAGGAMAYRLACEY 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 734902759 147 PELVRGIAALSGsvlPVLRSALKPDAAMGK-LAIFIGHGTLDQALPFSSATQA 198
Cdd:COG3509  156 PDVFAAVAPVAG---LPYGAASDAACAPGRpVPVLVIHGTADPTVPYAGAEET 205
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
37-238 1.92e-13

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 67.35  E-value: 1.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  37 DARNQPLVIFLHGFGSNEEDLFgikDALPSTWtylsvraplpvAPQGYRWFTktdePEY--NGETDELFSSARL--IKDF 112
Cdd:COG1506   19 DGKKYPVVVYVHGGPGSRDDSF---LPLAQAL-----------ASRGYAVLA----PDYrgYGESAGDWGGDEVddVLAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 113 VLKATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSG----------------------SVLPVLRSALKP 170
Cdd:COG1506   81 IDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGvsdlrsyygttreyterlmggpWEDPEAYAARSP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734902759 171 DAAMGKLA--IFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTISEAE----IQDLKAWLEKSLK 238
Cdd:COG1506  161 LAYADKLKtpLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGapdyLERILDFLDRHLK 234
PRK11460 PRK11460
putative hydrolase; Provisional
 29-227 3.97e-13

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 66.22  E-value: 3.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  29 SYLEQTQGDARNQPLVIFLHGFGSNEEDLFGI----KDALPSTwTYLSVRAPLPVA-PQGYRWFTKTDEPEYNgetdELF 103
Cdd:PRK11460   4 DHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIgswfAPAFPDA-LVVSVGGPEPSGnGAGRQWFSVQGITEDN----RQA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 104 SSARLIKDFVlkATAKYHTQSDRVF-----LVGFSQGAIMSYEVALREPELVRGIAALSGsvlpvlRSALKPDAAMGKLA 178
Cdd:PRK11460  79 RVAAIMPTFI--ETVRYWQQQSGVGasataLIGFSQGAIMALEAVKAEPGLAGRVIAFSG------RYASLPETAPTATT 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 734902759 179 IFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTISEAEIQ 227
Cdd:PRK11460 151 IHLIHGGEDPVIDVAHAVAAQEALISLGGDVTLDIVEDLGHAIDPRLMQ 199
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
42-220 8.06e-12

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 63.72  E-value: 8.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  42 PLVIFLHGFGSNEEDLFGIKDAlpstWTYL-------SVRAPLPVAPQGYRwftkTDEPEYNGETDELFSSArLIKDFVL 114
Cdd:COG2382  113 PVLYLLDGGGGDEQDWFDQGRL----PTILdnliaagKIPPMIVVMPDGGD----GGDRGTEGPGNDAFERF-LAEELIP 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 115 KATAKYHTQSDR--VFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLP--------VLRSALKPDAAMGKLAIFIGHG 184
Cdd:COG2382  184 FVEKNYRVSADPehRAIAGLSMGGLAALYAALRHPDLFGYVGSFSGSFWWppgdadrgGWAELLAAGAPKKPLRFYLDVG 263

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 734902759 185 TLDQALPfsSATQANKVLAGLGLKPEFHEYPGmNHT 220
Cdd:COG2382  264 TEDDLLE--ANRALAAALKAKGYDVEYREFPG-GHD 296
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
42-219 1.66e-09

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 56.13  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  42 PLVIFLHGFGSNEEDLFGIKDALpstwtylsvraplpvAPQGYR-----WFTKTDEPEYNGETDELFSS---ARLIKDfv 113
Cdd:COG0412   30 PGVVVLHEIFGLNPHIRDVARRL---------------AAAGYVvlapdLYGRGGPGDDPDEARALMGAldpELLAAD-- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 114 LKATAKY-----HTQSDRVFLVGFSQGAIMSYEVALREPELvRGIAALSGSVLPVLRSALKPDAamgKLAIFIGHGTLDQ 188
Cdd:COG0412   93 LRAALDWlkaqpEVDAGRVGVVGFCFGGGLALLAAARGPDL-AAAVSFYGGLPADDLLDLAARI---KAPVLLLYGEKDP 168

                        170       180       190
                 ....*....|....*....|....*....|.
gi 734902759 189 ALPFSSATQANKVLAGLGLKPEFHEYPGMNH 219
Cdd:COG0412  169 LVPPEQVAALEAALAAAGVDVELHVYPGAGH 199
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
37-235 4.63e-08

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 51.93  E-value: 4.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  37 DARNQPLVIFLHGFGSNEEDLFGIKDALpstwtylsvraplpvAPQGYRWFT-------KTDepeynGETDELFSSARLI 109
Cdd:COG2267   24 AGSPRGTVVLVHGLGEHSGRYAELAEAL---------------AAAGYAVLAfdlrghgRSD-----GPRGHVDSFDDYV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 110 KDfVLKATAKYHTQSD-RVFLVGFSQGAIMSYEVALREPELVRGIAALSG--------SVLPVLRSALKPDAAMGKLA-- 178
Cdd:COG2267   84 DD-LRAALDALRARPGlPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPayradpllGPSARWLRALRLAEALARIDvp 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 734902759 179 IFIGHGTLDQALPFSSatqANKVLAGLGLKPEFHEYPGMNHTI-----SEAEIQDLKAWLEK 235
Cdd:COG2267  163 VLVLHGGADRVVPPEA---ARRLAARLSPDVELVLLPGARHELlnepaREEVLAAILAWLER 221
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 42-236 7.14e-08

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 51.54  E-value: 7.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  42 PLVIFLHGFGSNEEDLFGIKDALPSTWTylsVRAPlpvapqGYRWFTKTDEPEYNGETDELfssARLIKDFVLkatakyH 121
Cdd:COG0596   24 PPVVLLHGLPGSSYEWRPLIPALAAGYR---VIAP------DLRGHGRSDKPAGGYTLDDL---ADDLAALLD------A 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 122 TQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVLRSALKPDAAMGKLAIFIG------------------- 182
Cdd:COG0596   86 LGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAALAEPLRRPGLAPEALAALLRalartdlrerlaritvptl 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 183 --HGTLDQALPFSSATQANKVLAGLglkpEFHEYPGMNHTISEAE----IQDLKAWLEKS 236
Cdd:COG0596  166 viWGEKDPIVPPALARRLAELLPNA----ELVVLPGAGHFPPLEQpeafAAALRDFLARL 221
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 38-158 6.89e-07

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 46.36  E-value: 6.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  38 ARNQPLVIFLHGFGSNEEDLFGIKDALPStwtylsvraplpvapQGYRWFTktdePEYNGETDELFSSARLIKDFVlkAT 117
Cdd:COG1075    2 AATRYPVVLVHGLGGSAASWAPLAPRLRA---------------AGYPVYA----LNYPSTNGSIEDSAEQLAAFV--DA 60

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 734902759 118 AKYHTQSDRVFLVGFSQGAIMSYEVA--LREPELVRGIAALSG 158
Cdd:COG1075   61 VLAATGAEKVDLVGHSMGGLVARYYLkrLGGAAKVARVVTLGT 103
Esterase_PHB pfam10503
Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), ...
 36-197 3.10e-05

Esterase PHB depolymerase; This family of proteins include acetyl xylan esterases (AXE), feruloyl esterases (FAE), and poly(3-hydroxybutyrate) (PHB) depolymerases.


Pssm-ID: 431322 [Multi-domain]  Cd Length: 222  Bit Score: 43.51  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   36 GDARNQPLVIFLHGFGSNEEDLF-GIKDALPSTWTYLSVRAPLPV----APQGYRWFTKTDEPEYNGETDELFSSARLIk 110
Cdd:pfam10503  13 GDGAPMPLVVMLHGCKQHADDFAaGTRINALADELGFAVLYPEQSkhahAHKCWNWFDEQGAARGGGEAASIAALAKAI- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  111 dfvlkaTAKYHTQSDRVFLVGFSQGAIMSYEVALREPE----------LVRGIAALSGSVLPVLRSALKPD--------- 171
Cdd:pfam10503  92 ------AAAHRLDGARVYLAGLSAGAALAALLAHCYPDvfaavglhsgLPFGCAADAASALDAMRRGPGPApgalidaas 165

                         170       180
                  ....*....|....*....|....*...
gi 734902759  172 --AAMGKLAIFIGHGTLDQALPFSSATQ 197
Cdd:pfam10503 166 dvRSYPALPAIIFHGDADSTVASANADQ 193
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
109-238 3.86e-05

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 43.37  E-value: 3.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  109 IKDFVL---KATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGsVLPVLRSALKPDAA-----MGKL--- 177
Cdd:pfam00326  45 FDDFIAaaeYLIEQGYTDPDRLAIWGGSYGGYLTGAALNQRPDLFKAAVAHVP-VVDWLAYMSDTSLPfteryMEWGnpw 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  178 ----------------------AIFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNHTI-----SEAEIQDLK 230
Cdd:pfam00326 124 dneegydylspyspadnvkvypPLLLIHGLLDDRVPPWQSLKLVAALQRKGVPFLLLIFPDEGHGIgkprnKVEEYAREL 203


                  ....*...
gi 734902759  231 AWLEKSLK 238
Cdd:pfam00326 204 AFLLEYLG 211
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 42-189 1.06e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.11  E-value: 1.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   42 PLVIFLHGFGSNEEDLFGIKDALpstwtylsvraplpvAPQGY-------RWFTKTDEPEYNGEtdelFSSARLIKDFvl 114
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPAL---------------ARDGFrvialdlRGFGKSSRPKAQDD----YRTDDLAEDL-- 59

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 734902759  115 kATAKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIaalsgsvlpVLRSALKPDAAMGKLAIFIGHGTLDQA 189
Cdd:pfam00561  60 -EYILEALGLEKVNLVGHSMGGLIALAYAAKYPDRVKAL---------VLLGALDPPHELDEADRFILALFPGFF 124
DLH pfam01738
Dienelactone hydrolase family;
97-219 1.52e-04

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 41.57  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   97 GETDELFSSARLIKDF---VLKATAKYHTQSDRVFLVGFSQGAIMSYEVAlREPELVRGIAALSGsVLPVLRSALKPDAa 173
Cdd:pfam01738  65 FELVSKRVMEKVLDDLeaaVNYLKSQPEVSPKKVGVVGYCMGGALAVLLA-AKGPLVDAAVGFYG-VGPEPPLIEAPDI- 141

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 734902759  174 mgKLAIFIGHGTLDQALPFSSATQANKVLAGLGLKPEFHEYPGMNH 219
Cdd:pfam01738 142 --KAPILFHFGEEDHFVPADSRELIEEALKAANVDHQIHSYPGAGH 185
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
111-238 2.83e-04

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 40.63  E-value: 2.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 111 DFVLKATAKYHTQSDRVFLVGFSQGAIMSYEVALREPElvRGIAALSGSVL--PVLRSALKP-DAAMGKLA-IFIGHGTL 186
Cdd:COG0657   72 RWLRANAAELGIDPDRIAVAGDSAGGHLAAALALRARD--RGGPRPAAQVLiyPVLDLTASPlRADLAGLPpTLIVTGEA 149

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734902759 187 D----QALPFSSAtqankvLAGLGLKPEFHEYPGMNH--------TISEAEIQDLKAWLEKSLK 238
Cdd:COG0657  150 DplvdESEALAAA------LRAAGVPVELHVYPGGGHgfgllaglPEARAALAEIAAFLRRALA 207
Esterase pfam00756
Putative esterase; This family contains Esterase D. However it is not clear if all members of ...
 30-219 2.88e-04

Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.


Pssm-ID: 395613 [Multi-domain]  Cd Length: 246  Bit Score: 40.91  E-value: 2.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   30 YLEQTQGDARNQPLVIFLHGfgSNEEDLFGIKDAL-PSTWTYLSVRAPLPVAPQG--YRWFTKTDEPEYNGEtdelFSSA 106
Cdd:pfam00756  13 YLPEDYPPGRKYPVLYLLDG--TGWFQNGPAKEGLdRLAASGEIPPVIIVGSPRGgeVSFYSDWDRGLNATE----GPGA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  107 RLIKDFV---LKAT--AKYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSVLPVL--------------RSA 167
Cdd:pfam00756  87 YAYETFLtqeLPPLldANFPTAPDGRALAGQSMGGLGALYLALKYPDLFGSVSSFSPILNPSNsmwgpeddpawqegDPV 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 734902759  168 LKPDAAMGK---LAIFIGHGTLDQALP------FSSATQANKVLAGL----GLKPEFHEYPGMNH 219
Cdd:pfam00756 167 LLAVALSANntrLRIYLDVGTREDFLGdqlpveILEELAPNRELAEQlayrGVGGYDHEYYGGHD 231
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 36-165 4.75e-04

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 41.00  E-value: 4.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759   36 GDARNQPLVIFLHGFGSNEEDLFGIKDALPSTWTYLSVRAPlpvapqGYrwfTKTDEPEYNGETDELFS-SARLIKDFVL 114
Cdd:PLN02980 1366 GQNAEGSVVLFLHGFLGTGEDWIPIMKAISGSARCISIDLP------GH---GGSKIQNHAKETQTEPTlSVELVADLLY 1436

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 734902759  115 KATakYHTQSDRVFLVGFSQGAIMSYEVALREPELVRGIAALSGSvlPVLR 165
Cdd:PLN02980 1437 KLI--EHITPGKVTLVGYSMGARIALYMALRFSDKIEGAVIISGS--PGLK 1483
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
44-235 1.09e-03

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 39.15  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759  44 VIFLHGFGSNEEDLFGIKDALPST-WTYLSVRapLPvapqGYrwftktdepeynGETDELFSSARlIKDFVLKATAKYHT 122
Cdd:COG1647   18 VLLLHGFTGSPAEMRPLAEALAKAgYTVYAPR--LP----GH------------GTSPEDLLKTT-WEDWLEDVEEAYEI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 123 ---QSDRVFLVGFSQGAIMSYEVALREPElVRGIAALSGSV---------LPVLRSALK-----------PDAAMGKLA- 178
Cdd:COG1647   79 lkaGYDKVIVIGLSMGGLLALLLAARYPD-VAGLVLLSPALkiddpsaplLPLLKYLARslrgigsdiedPEVAEYAYDr 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 734902759 179 --------------------------IFIGHGTLDQALPFSSatqANKVLAGLGLKP-EFHEYPGMNHTIS---EAE--I 226
Cdd:COG1647  158 tplralaelqrlirevrrdlpkitapTLIIQSRKDEVVPPES---ARYIYERLGSPDkELVWLEDSGHVITldkDREevA 234


                 ....*....
gi 734902759 227 QDLKAWLEK 235
Cdd:COG1647  235 EEILDFLER 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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