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Conserved domains on  [gi|734881648|ref|WP_034128025|]
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MULTISPECIES: Fe-S cluster assembly protein IscX [Pseudomonas]

Protein Classification

Fe-S cluster assembly protein IscX( domain architecture ID 10516386)

Fe-S cluster assembly protein IscX may function as iron donor in the assembly of iron-sulfur clusters

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 3-66 1.35e-32

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 442214  Cd Length: 64  Bit Score: 106.42  E-value: 1.35e-32
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734881648  3 LKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
 
Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 3-66 1.35e-32

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442214  Cd Length: 64  Bit Score: 106.42  E-value: 1.35e-32
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734881648  3 LKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
Fe-S_assembly pfam04384
Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the ...
 3-66 2.34e-32

Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli Swiss:P0C0L9 forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.


Pssm-ID: 427912  Cd Length: 64  Bit Score: 105.68  E-value: 2.34e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734881648   3 LKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:pfam04384  1 MKWTDTEDIAIALYEKYPDVDPLTVRFTDLHEWVLELPGFDDDPEKSNEKILEAIQMAWIEERE 64
iscX_yfhJ TIGR03412
FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC ...
 4-66 3.80e-31

FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC system for iron-sulfur cluster assembly. Other genes in the system include iscSUA, hscBA, and fdx. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 132453  Cd Length: 63  Bit Score: 102.75  E-value: 3.80e-31
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 734881648   4 KWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:TIGR03412  1 KWTDSQEIAIALAEAHPDVDPKTVRFTDLHQWVLELPGFDDDPKRCNEKILEAIQMAWIDERE 63
PRK10721 PRK10721
hypothetical protein; Provisional
 1-66 8.40e-16

hypothetical protein; Provisional


Pssm-ID: 170660  Cd Length: 66  Bit Score: 64.12  E-value: 8.40e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 734881648  1 MSLKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:PRK10721  1 MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICELEDFDDDPQASNEKILEAILLVWLDEAE 66
 
Name Accession Description Interval E-value
IscX COG2975
Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, ...
 3-66 1.35e-32

Fe-S-cluster formation regulator IscX/YfhJ [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442214  Cd Length: 64  Bit Score: 106.42  E-value: 1.35e-32
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734881648  3 LKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:COG2975   1 MKWTDTEDIAIALYEKHPDVDPLTVRFTDLHRWVLELPGFDDDPERSNEKILEAIQMAWIEEAE 64
Fe-S_assembly pfam04384
Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the ...
 3-66 2.34e-32

Iron-sulphur cluster assembly; This family of proteins is likely to be involved in the assembly of iron-sulphur clusters. It may function as an adaptor protein. In Escherichia coli Swiss:P0C0L9 forms part of the isc operon, which encodes genes involved in iron-sulphur cluster assembly. Its structure is entirely alpha helical, and it contains a modified wing-helix structure, usually found in DNA-binding proteins. It binds to Fe2+ and Fe3+ ions and to the cysteine desulfurase IscS, the same surface of the protein is involved in both binding to iron and to IscS.


Pssm-ID: 427912  Cd Length: 64  Bit Score: 105.68  E-value: 2.34e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 734881648   3 LKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:pfam04384  1 MKWTDTEDIAIALYEKYPDVDPLTVRFTDLHEWVLELPGFDDDPEKSNEKILEAIQMAWIEERE 64
iscX_yfhJ TIGR03412
FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC ...
 4-66 3.80e-31

FeS assembly protein IscX; Members of this protein family are YfhJ, a protein of the ISC system for iron-sulfur cluster assembly. Other genes in the system include iscSUA, hscBA, and fdx. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 132453  Cd Length: 63  Bit Score: 102.75  E-value: 3.80e-31
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 734881648   4 KWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:TIGR03412  1 KWTDSQEIAIALAEAHPDVDPKTVRFTDLHQWVLELPGFDDDPKRCNEKILEAIQMAWIDERE 63
PRK10721 PRK10721
hypothetical protein; Provisional
 1-66 8.40e-16

hypothetical protein; Provisional


Pssm-ID: 170660  Cd Length: 66  Bit Score: 64.12  E-value: 8.40e-16
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 734881648  1 MSLKWVDVQEIAIQLAEAHPEVNPLTVNFVKLRDLVMALPDFDDIPDRGGEKVLEAIQGLWIEEAD 66
Cdd:PRK10721  1 MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICELEDFDDDPQASNEKILEAILLVWLDEAE 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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