NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|727363282|ref|WP_033800993|]
View 

type-F conjugative transfer system secretin TraK, partial [Escherichia coli]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TraK super family cl05878
TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella ...
 1-95 2.47e-51

TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.


The actual alignment was detected with superfamily member PRK13736:

Pssm-ID: 446824  Cd Length: 245  Bit Score: 161.04  E-value: 2.47e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282   1 VRGGKLPAGWYQVPVTKETLQAPAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLLA 80
Cdd:PRK13736 148 VRGGKLPAGYYQVPVTKETLQAPAGLSLTADRVWTGNHLKVVRYRVENPTLSARNLRESDFWQPGTRAVMFSQPARQLLA 227

                         90
                 ....*....|....*
gi 727363282  81 GARMDVYVIRDGEGN 95
Cdd:PRK13736 228 GGRMDVYVIRDGEGN 242
 
Name Accession Description Interval E-value
PRK13736 PRK13736
conjugal transfer protein TraK; Provisional
 1-95 2.47e-51

conjugal transfer protein TraK; Provisional


Pssm-ID: 237486  Cd Length: 245  Bit Score: 161.04  E-value: 2.47e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282   1 VRGGKLPAGWYQVPVTKETLQAPAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLLA 80
Cdd:PRK13736 148 VRGGKLPAGYYQVPVTKETLQAPAGLSLTADRVWTGNHLKVVRYRVENPTLSARNLRESDFWQPGTRAVMFSQPARQLLA 227

                         90
                 ....*....|....*
gi 727363282  81 GARMDVYVIRDGEGN 95
Cdd:PRK13736 228 GGRMDVYVIRDGEGN 242
TraK_Ftype TIGR02756
type-F conjugative transfer system secretin TraK; The TraK protein is predicted to interact ...
 1-90 4.02e-36

type-F conjugative transfer system secretin TraK; The TraK protein is predicted to interact with the TraV and TraB proteins as part of the scaffold which extends from the inner membrane, through the periplasm to the cell envelope and through which the F-type conjugative pilus passes. TraK is homologous to the P-type IV secretion system protein TrbG, the Ti-type protein VirB9 and the I-type TraN protein. The protein is related to the secretin family especially the HrcC subgroup of the type III secretion system. The protein is hypothesized to oligomerize to form a ring structure akin to other secretins.


Pssm-ID: 274283  Cd Length: 232  Bit Score: 121.85  E-value: 4.02e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282    1 VRGGKLPAGWYQVPVTKETLQAPAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPasQLLA 80
Cdd:TIGR02756 145 LRGGTLPAGFYQIPVTPEALQLPAGLSVRPDAVWTGNHLKGERFELENKTNSPLELTESWFWQPGTRAVALSKP--QLAP 222

                          90
                  ....*....|
gi 727363282   81 GARMDVYVIR 90
Cdd:TIGR02756 223 GETADLYRIR 232
TraK pfam06586
TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella ...
 1-87 5.76e-18

TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.


Pssm-ID: 429019  Cd Length: 228  Bit Score: 74.73  E-value: 5.76e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282    1 VRGGKLPAGWYQVPVTKETLQ--APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPasQL 78
Cdd:pfam06586 142 MYTDRIPDGFSVVEVRKEVVLptEAGGLRLQRIAEYEGAGLTGEVYRLENVSTSPVTLDEAEFLRPGVLAVAIERP--TL 219


                  ....*....
gi 727363282   79 LAGARMDVY 87
Cdd:pfam06586 220 APGETTRVY 228
 
Name Accession Description Interval E-value
PRK13736 PRK13736
conjugal transfer protein TraK; Provisional
 1-95 2.47e-51

conjugal transfer protein TraK; Provisional


Pssm-ID: 237486  Cd Length: 245  Bit Score: 161.04  E-value: 2.47e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282   1 VRGGKLPAGWYQVPVTKETLQAPAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLLA 80
Cdd:PRK13736 148 VRGGKLPAGYYQVPVTKETLQAPAGLSLTADRVWTGNHLKVVRYRVENPTLSARNLRESDFWQPGTRAVMFSQPARQLLA 227

                         90
                 ....*....|....*
gi 727363282  81 GARMDVYVIRDGEGN 95
Cdd:PRK13736 228 GGRMDVYVIRDGEGN 242
TraK_Ftype TIGR02756
type-F conjugative transfer system secretin TraK; The TraK protein is predicted to interact ...
 1-90 4.02e-36

type-F conjugative transfer system secretin TraK; The TraK protein is predicted to interact with the TraV and TraB proteins as part of the scaffold which extends from the inner membrane, through the periplasm to the cell envelope and through which the F-type conjugative pilus passes. TraK is homologous to the P-type IV secretion system protein TrbG, the Ti-type protein VirB9 and the I-type TraN protein. The protein is related to the secretin family especially the HrcC subgroup of the type III secretion system. The protein is hypothesized to oligomerize to form a ring structure akin to other secretins.


Pssm-ID: 274283  Cd Length: 232  Bit Score: 121.85  E-value: 4.02e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282    1 VRGGKLPAGWYQVPVTKETLQAPAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPasQLLA 80
Cdd:TIGR02756 145 LRGGTLPAGFYQIPVTPEALQLPAGLSVRPDAVWTGNHLKGERFELENKTNSPLELTESWFWQPGTRAVALSKP--QLAP 222

                          90
                  ....*....|
gi 727363282   81 GARMDVYVIR 90
Cdd:TIGR02756 223 GETADLYRIR 232
TraK pfam06586
TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella ...
 1-87 5.76e-18

TraK protein; This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.


Pssm-ID: 429019  Cd Length: 228  Bit Score: 74.73  E-value: 5.76e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727363282    1 VRGGKLPAGWYQVPVTKETLQ--APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPasQL 78
Cdd:pfam06586 142 MYTDRIPDGFSVVEVRKEVVLptEAGGLRLQRIAEYEGAGLTGEVYRLENVSTSPVTLDEAEFLRPGVLAVAIERP--TL 219


                  ....*....
gi 727363282   79 LAGARMDVY 87
Cdd:pfam06586 220 APGETTRVY 228
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH