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Conserved domains on  [gi|727185624|ref|WP_033647568|]
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MULTISPECIES: DeoR/GlpR family DNA-binding transcription regulator [Serratia]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 12-263 9.89e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 9.89e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLERQVNLTAKDRIG 91
Cdd:COG1349    4 EERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAIA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  92 KLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTSGDKAAGFFEN 171
Cdd:COG1349   84 RAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALRR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 172 VLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYLITDDGISNTAIQA 251
Cdd:COG1349  164 FRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARV-APLSEIDVLITDAGPPPELLEA 242

                        250
                 ....*....|..
gi 727185624 252 FEKVGVKVLVAG 263
Cdd:COG1349  243 LEEAGVEVIVAE 254
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 12-263 9.89e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 9.89e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLERQVNLTAKDRIG 91
Cdd:COG1349    4 EERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAIA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  92 KLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTSGDKAAGFFEN 171
Cdd:COG1349   84 RAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALRR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 172 VLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYLITDDGISNTAIQA 251
Cdd:COG1349  164 FRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARV-APLSEIDVLITDAGPPPELLEA 242

                        250
                 ....*....|..
gi 727185624 252 FEKVGVKVLVAG 263
Cdd:COG1349  243 LEEAGVEVIVAE 254
AgaR NF040755
transcriptional repressor AgaR;
1-262 3.37e-64

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 201.34  E-value: 3.37e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   1 MKSKSEqlaemqqRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLE- 79
Cdd:NF040755   1 MKGTSE-------RREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAEPSVEd 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  80 -RQVNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTL 158
Cdd:NF040755  74 kSRLNTAVKRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 159 STSGDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSmFALPCDWQHIDYL 238
Cdd:NF040755 154 SFYGDQAEQSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSS-LHKIRDTGRIDTL 232

                        250       260
                 ....*....|....*....|....
gi 727185624 239 ITDDGISNTAIQAFEKVGVKVLVA 262
Cdd:NF040755 233 ITDSGIPEEYLQGLRKLGVEVILV 256
PRK09802 PRK09802
DeoR family transcriptional regulator;
1-264 4.83e-51

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 168.11  E-value: 4.83e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   1 MKSKSEQLAEMQQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLER 80
Cdd:PRK09802   5 DASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVED 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  81 Q--VNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTL 158
Cdd:PRK09802  85 KsaLNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQ 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 159 STSGDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYL 238
Cdd:PRK09802 165 SFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKI-IDTQRIDMI 243

                        250       260
                 ....*....|....*....|....*.
gi 727185624 239 ITDDGISNTAIQAFEKVGVKVLVAGA 264
Cdd:PRK09802 244 IVDEGIPADSLEGLRKAGVEVILVGE 269
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 82-241 5.56e-51

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 164.22  E-value: 5.56e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   82 VNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTS 161
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  162 GDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYLITD 241
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARF-APLEDIDALITD 159
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
14-66 4.09e-12

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 59.54  E-value: 4.09e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 727185624    14 RREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATL 66
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 12-263 9.89e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 271.24  E-value: 9.89e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLERQVNLTAKDRIG 91
Cdd:COG1349    4 EERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNAEEKRAIA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  92 KLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTSGDKAAGFFEN 171
Cdd:COG1349   84 RAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPNIEVILLGGELRPSSGSLVGPLAEEALRR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 172 VLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYLITDDGISNTAIQA 251
Cdd:COG1349  164 FRADKAFLGASGIDAEGGLTTFDEEEAEVKRAMIEAARRVILLADSSKFGRRALARV-APLSEIDVLITDAGPPPELLEA 242

                        250
                 ....*....|..
gi 727185624 252 FEKVGVKVLVAG 263
Cdd:COG1349  243 LEEAGVEVIVAE 254
AgaR NF040755
transcriptional repressor AgaR;
1-262 3.37e-64

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 201.34  E-value: 3.37e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   1 MKSKSEqlaemqqRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLE- 79
Cdd:NF040755   1 MKGTSE-------RREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDGFIPGAEPSVEd 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  80 -RQVNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTL 158
Cdd:NF040755  74 kSRLNTAVKRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVEVLMTGGHLRRQSL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 159 STSGDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSmFALPCDWQHIDYL 238
Cdd:NF040755 154 SFYGDQAEQSLQNYHFDKLFLGVDGFDLERGITTHNEDEARLNRRMCEVAERIIAVTDSSKFGRSS-LHKIRDTGRIDTL 232

                        250       260
                 ....*....|....*....|....
gi 727185624 239 ITDDGISNTAIQAFEKVGVKVLVA 262
Cdd:NF040755 233 ITDSGIPEEYLQGLRKLGVEVILV 256
PRK09802 PRK09802
DeoR family transcriptional regulator;
1-264 4.83e-51

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 168.11  E-value: 4.83e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   1 MKSKSEQLAEMQQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMLLER 80
Cdd:PRK09802   5 DASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVED 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  81 Q--VNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTL 158
Cdd:PRK09802  85 KsaLNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQ 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 159 STSGDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYL 238
Cdd:PRK09802 165 SFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKI-IDTQRIDMI 243

                        250       260
                 ....*....|....*....|....*.
gi 727185624 239 ITDDGISNTAIQAFEKVGVKVLVAGA 264
Cdd:PRK09802 244 IVDEGIPADSLEGLRKAGVEVILVGE 269
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 82-241 5.56e-51

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 164.22  E-value: 5.56e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624   82 VNLTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTS 161
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPDIEVILLGGEVRPKTGAFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  162 GDKAAGFFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALpCDWQHIDYLITD 241
Cdd:pfam00455  81 GPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEEEAEVKRAMIEAARRVILLADSSKFGKRAFARF-APLEDIDALITD 159
srlR PRK10434
DNA-binding transcriptional repressor;
12-263 1.73e-44

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 150.61  E-value: 1.73e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATL--------VDGKQNthamllerqVN 83
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLnkeesdppIDHKTL---------IN 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  84 LTAKDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTG---VNIALQLGGEpgVNILLTGGSFKFPTLST 160
Cdd:PRK10434  75 THKKELIAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSlhiVNALSELDNE--QTILMPGGTFRKKSASF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 161 SGDKAAGFFENVLAQKLFLATACISPRHGLSFPSETdIKLKTAMINAANTVYVVADSSKIDKVSmfalP---CDWQHIDY 237
Cdd:PRK10434 153 HGQLAENAFEHFTFDKLFIGTDGIDLNAGVTTFNEV-YTVSKAMCNAAREIILMADSSKFGRKS----PnvvCSLEKVDK 227

                        250       260
                 ....*....|....*....|....*.
gi 727185624 238 LITDDGISNTAIQAFEKVGVKVLVAG 263
Cdd:PRK10434 228 LITDAGIDPAFRQALEEKGIEVIITG 253
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
13-259 5.78e-23

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 94.15  E-value: 5.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  13 QRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHAMllERQVNLTA-KDRIG 91
Cdd:PRK10906   5 QRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSSSVNTPWH--DRKATQTEeKERIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  92 KLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFKFPTLSTSGDKAAGFFEN 171
Cdd:PRK10906  83 RKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATLDFISQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 172 VLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKVSMFALPcDWQHIDYLITDDGISNTAIQA 251
Cdd:PRK10906 163 FRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMG-SISMVDAVYTDQLPPASVMQV 241


                 ....*...
gi 727185624 252 FEKVGVKV 259
Cdd:PRK10906 242 IEDHHVQL 249
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
12-262 4.77e-21

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 88.91  E-value: 4.77e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVD-GKQNTHAMLLERQVNLTAKDRI 90
Cdd:PRK13509   4 AQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEAITqQRPRWTPMNIHQAQNHDEKVRI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  91 GKLAAGFIEPGDTIILDSGTTTTAIANHLSHiKKLSVITTGVNIALQLGGEPGVNILLTGGSF---KFPTLSTSGDKAAG 167
Cdd:PRK13509  84 AKAASQLCNPGESVVINCGSTAFLLGRELCG-KPVQIITNYLPLANYLIDQEHDSVIIMGGQYnksQSITLSPQGSENSL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 168 FFENVlaqkLFLATACISPrHGLsfpSETDIKLKTA---MINAANTVYVVADSSKIDK-VSMfaLPCDWQHIDYLITDDG 243
Cdd:PRK13509 163 YAGHW----MFTSGKGLTA-DGL---YKTDMLTAMAeqkMLSVVGKLVVLVDSSKIGErAGM--LFSRADQIDMLITGKN 232

                        250
                 ....*....|....*....
gi 727185624 244 ISNTAIQAFEKVGVKVLVA 262
Cdd:PRK13509 233 ADPEVLQQLEAQGVSILLV 251
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 11-241 6.33e-15

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 72.04  E-value: 6.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  11 MQQRREKILDMIREDGSATVKM-LTDTFKL---TEATIRTDLR-----VLQQQGYVqrfhggatLVDGKQNTHAMLLERQ 81
Cdd:PRK10681   1 METRRDERIGQLLQALKRSDKLhLKDAAALlgvSEMTIRRDLNahsapVVLLGGYI--------VLEPRSASHYLLSDQK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  82 VNLTA-KDRIGKLAAGFIEPGDTIILDSGTTTTAIANHLSHIKKLSVITTGVNIALQLGGEPGVNILLTGGSFK-----F 155
Cdd:PRK10681  73 SRLVEeKRRAAQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTAVCYSLNTFLALQEKPHCRAILCGGEFHasnaiF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624 156 PTLSTSGDkaagfFENVLAQKLFLATACISPRHGLSFPSETDIKLKTAMINAANTVYVVADSSKIDKV---SMFALpcdw 232
Cdd:PRK10681 153 KPLDFQQT-----LDNICPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMAMAQKHVLVVDHSKFGKVrpaRMGDL---- 223


                 ....*....
gi 727185624 233 QHIDYLITD 241
Cdd:PRK10681 224 TRFDTVVSD 232
PRK10411 PRK10411
L-fucose operon activator;
14-151 1.92e-12

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 65.21  E-value: 1.92e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  14 RREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVDGKQNTHA--MLLERQVNLTAKDRIG 91
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGdpFHIRLKSHYAHKADIA 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 727185624  92 KLAAGFIEPGDTIILDSGTTTTAIANHLSHIkKLSVITTGVNIALQLGGEPGVNILLTGG 151
Cdd:PRK10411  85 REALAWIEEGMVIALDASSTCWYLARQLPDI-NIQVFTNSHPICQELGKRERIQLISSGG 143
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
14-66 4.09e-12

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 59.54  E-value: 4.09e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 727185624    14 RREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATL 66
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
14-68 4.73e-11

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 56.88  E-value: 4.73e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 727185624   14 RREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATLVD 68
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNS 55
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
1-59 5.51e-07

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 49.15  E-value: 5.51e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 727185624   1 MKSKSEQLAEMQQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQR 59
Cdd:COG2345    1 MTDTPALAALADPTRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVER 59
PHA00738 PHA00738
putative HTH transcription regulator
 12-74 1.36e-03

putative HTH transcription regulator


Pssm-ID: 177305  Cd Length: 108  Bit Score: 37.64  E-value: 1.36e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 727185624  12 QQRREKILDMIREDGSATVKMLTDTFKLTEATIRTDLRVLQQQGYVQRFHGGATL-VDGKQNTH 74
Cdd:PHA00738  11 KILRRKILELIAENYILSASLISHTLLLSYTTVLRHLKILNEQGYIELYKEGRTLyAKIRENSK 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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