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Conserved domains on  [gi|727180703|ref|WP_033643175|]
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MULTISPECIES: alpha/beta fold hydrolase [Serratia]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 15-292 5.46e-37

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 131.28  E-value: 5.46e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  15 AEHVYTQVNGRRLHCVVAG-EGRPVLLIPGWPQTWYTWRYVMRALAAaGFQAIAVDPPGIGDSDKPAGGYDTGSIGAALH 93
Cdd:COG0596    2 STPRFVTVDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  94 AMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIpglappppifvapeeniflwhfmfnqladlpetltq 173
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL------------------------------------ 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 174 grereylgyifnrwsyrrdrvaaKVYIAAYSAPGGLRAGFdyYRAIPETVRQNRLRAATPLTMPVLTVGAEH--ATGDAP 251
Cdd:COG0596  125 -----------------------AALAEPLRRPGLAPEAL--AALLRALARTDLRERLARITVPTLVIWGEKdpIVPPAL 179

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 727180703 252 LTTLRGNARDLRGETVAGCGHFITEECHEAFIALIAPFLAG 292
Cdd:COG0596  180 ARRLAELLPNAELVVLPGAGHFPPLEQPEAFAAALRDFLAR 220
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 15-292 5.46e-37

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 131.28  E-value: 5.46e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  15 AEHVYTQVNGRRLHCVVAG-EGRPVLLIPGWPQTWYTWRYVMRALAAaGFQAIAVDPPGIGDSDKPAGGYDTGSIGAALH 93
Cdd:COG0596    2 STPRFVTVDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  94 AMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIpglappppifvapeeniflwhfmfnqladlpetltq 173
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL------------------------------------ 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 174 grereylgyifnrwsyrrdrvaaKVYIAAYSAPGGLRAGFdyYRAIPETVRQNRLRAATPLTMPVLTVGAEH--ATGDAP 251
Cdd:COG0596  125 -----------------------AALAEPLRRPGLAPEAL--AALLRALARTDLRERLARITVPTLVIWGEKdpIVPPAL 179

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 727180703 252 LTTLRGNARDLRGETVAGCGHFITEECHEAFIALIAPFLAG 292
Cdd:COG0596  180 ARRLAELLPNAELVVLPGAGHFPPLEQPEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 37-274 1.62e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 79.86  E-value: 1.62e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703   37 PVLLIPGWPQTWYTWRYVMRALAAAGFQAIAVDPPGIGDSDKP--AGGYDTGSIGAALHAMMAQLGHQRYQLVGHDIGMW 114
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPkaQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMGGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  115 IGYAMASDFPQAVERLVLTEAvipgLAPPPPIFVAPEENIFLWHFMFNQLADLPETLTQGRERE-YLGYIFNRWsyRRDR 193
Cdd:pfam00561  82 IALAYAAKYPDRVKALVLLGA----LDPPHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAkLLALLLLRL--RLLK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  194 VAAKVYIAAYS-----APGGLRAGFDYYRAIPETVRQNRLRAatpLTMPVLTVgaeHATGD--APLTTLRGNARDL---R 263
Cdd:pfam00561 156 ALPLLNKRFPSgdyalAKSLVTGALLFIETWSTELRAKFLGR---LDEPTLII---WGDQDplVPPQALEKLAQLFpnaR 229

                         250
                  ....*....|.
gi 727180703  264 GETVAGCGHFI 274
Cdd:pfam00561 230 LVVIPDAGHFA 240
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 26-293 6.74e-17

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 79.24  E-value: 6.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  26 RLHCVVAG--EGRPVLLIPGWPqTW-YTWRYVMRALAAAGFQAIAVDPPGIGDSDKPA--GGYDTGSIGAALHAMMAQLG 100
Cdd:PRK00870  35 RMHYVDEGpaDGPPVLLLHGEP-SWsYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTrrEDYTYARHVEWMRSWFEQLD 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 101 HQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIP-GLAPPPPIFVApeeniflWhFMFNQLA-DLPetltqgrere 178
Cdd:PRK00870 114 LTDVTLVCQDWGGLIGLRLAAEHPDRFARLVVANTGLPtGDGPMPDAFWA-------W-RAFSQYSpVLP---------- 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 179 yLGYIFNRWSYRrdRVAAKVyIAAYSAP---GGLRAGfdyYRAIPETV---------RQNRL--RAATPLTMPVLTVGAE 244
Cdd:PRK00870 176 -VGRLVNGGTVR--DLSDAV-RAAYDAPfpdESYKAG---ARAFPLLVptspddpavAANRAawAVLERWDKPFLTAFSD 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 727180703 245 H----ATGDAPLTTLRGNARDLRGETVAGCGHFITEECHEAFIALIAPFLAGE 293
Cdd:PRK00870 249 SdpitGGGDAILQKRIPGAAGQPHPTIKGAGHFLQEDSGEELAEAVLEFIRAT 301
hydr2_PEP TIGR03101
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha ...
 56-139 2.94e-03

exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 1, TIGR03100) of the same superfamily.


Pssm-ID: 274428  Cd Length: 266  Bit Score: 38.64  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703   56 RALAAAGFQAIAVDPPGIGDSdkpAGGYDTGSIG------AALHAMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVER 129
Cdd:TIGR03101  50 RAFAAGGFGVLQIDLYGCGDS---AGDFAAARWDvwkedvAAAYRWLIEQGHPPVTLWGLRLGALLALDAANPLAAKCNR 126

                          90
                  ....*....|
gi 727180703  130 LVLTEAVIPG 139
Cdd:TIGR03101 127 LVLWQPVVSG 136
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 15-292 5.46e-37

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 131.28  E-value: 5.46e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  15 AEHVYTQVNGRRLHCVVAG-EGRPVLLIPGWPQTWYTWRYVMRALAAaGFQAIAVDPPGIGDSDKPAGGYDTGSIGAALH 93
Cdd:COG0596    2 STPRFVTVDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  94 AMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIpglappppifvapeeniflwhfmfnqladlpetltq 173
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL------------------------------------ 124

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 174 grereylgyifnrwsyrrdrvaaKVYIAAYSAPGGLRAGFdyYRAIPETVRQNRLRAATPLTMPVLTVGAEH--ATGDAP 251
Cdd:COG0596  125 -----------------------AALAEPLRRPGLAPEAL--AALLRALARTDLRERLARITVPTLVIWGEKdpIVPPAL 179

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 727180703 252 LTTLRGNARDLRGETVAGCGHFITEECHEAFIALIAPFLAG 292
Cdd:COG0596  180 ARRLAELLPNAELVVLPGAGHFPPLEQPEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 37-274 1.62e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 79.86  E-value: 1.62e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703   37 PVLLIPGWPQTWYTWRYVMRALAAAGFQAIAVDPPGIGDSDKP--AGGYDTGSIGAALHAMMAQLGHQRYQLVGHDIGMW 114
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPkaQDDYRTDDLAEDLEYILEALGLEKVNLVGHSMGGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  115 IGYAMASDFPQAVERLVLTEAvipgLAPPPPIFVAPEENIFLWHFMFNQLADLPETLTQGRERE-YLGYIFNRWsyRRDR 193
Cdd:pfam00561  82 IALAYAAKYPDRVKALVLLGA----LDPPHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAkLLALLLLRL--RLLK 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  194 VAAKVYIAAYS-----APGGLRAGFDYYRAIPETVRQNRLRAatpLTMPVLTVgaeHATGD--APLTTLRGNARDL---R 263
Cdd:pfam00561 156 ALPLLNKRFPSgdyalAKSLVTGALLFIETWSTELRAKFLGR---LDEPTLII---WGDQDplVPPQALEKLAQLFpnaR 229

                         250
                  ....*....|.
gi 727180703  264 GETVAGCGHFI 274
Cdd:pfam00561 230 LVVIPDAGHFA 240
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 26-293 6.74e-17

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 79.24  E-value: 6.74e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  26 RLHCVVAG--EGRPVLLIPGWPqTW-YTWRYVMRALAAAGFQAIAVDPPGIGDSDKPA--GGYDTGSIGAALHAMMAQLG 100
Cdd:PRK00870  35 RMHYVDEGpaDGPPVLLLHGEP-SWsYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTrrEDYTYARHVEWMRSWFEQLD 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 101 HQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIP-GLAPPPPIFVApeeniflWhFMFNQLA-DLPetltqgrere 178
Cdd:PRK00870 114 LTDVTLVCQDWGGLIGLRLAAEHPDRFARLVVANTGLPtGDGPMPDAFWA-------W-RAFSQYSpVLP---------- 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703 179 yLGYIFNRWSYRrdRVAAKVyIAAYSAP---GGLRAGfdyYRAIPETV---------RQNRL--RAATPLTMPVLTVGAE 244
Cdd:PRK00870 176 -VGRLVNGGTVR--DLSDAV-RAAYDAPfpdESYKAG---ARAFPLLVptspddpavAANRAawAVLERWDKPFLTAFSD 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 727180703 245 H----ATGDAPLTTLRGNARDLRGETVAGCGHFITEECHEAFIALIAPFLAGE 293
Cdd:PRK00870 249 SdpitGGGDAILQKRIPGAAGQPHPTIKGAGHFLQEDSGEELAEAVLEFIRAT 301
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 19-138 1.65e-16

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 78.11  E-value: 1.65e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  19 YTQVNGRRLHCVVAGEGRPVLLIPGWPQTWYTWRYVMRALAAAGfQAIAVDPPGIGDSDKPAGGYDTGSIGAALHAMMAQ 98
Cdd:PRK03592  11 RVEVLGSRMAYIETGEGDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKPDIDYTFADHARYLDAWFDA 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 727180703  99 LGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAVIP 138
Cdd:PRK03592  90 LGLDDVVLVGHDWGSALGFDWAARHPDRVRGIAFMEAIVR 129
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
16-133 1.40e-10

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 60.02  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  16 EHVYTQVNGRRLHCVV----AGEGRPVLLIPGWPQTWYTWRYVMRALAAAGFQAIAVDPPGIGDSDKPAGGYDT-GSIGA 90
Cdd:COG2267    5 LVTLPTRDGLRLRGRRwrpaGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSfDDYVD 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 727180703  91 ALHAMMAQL---GHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLT 133
Cdd:COG2267   85 DLRAALDALrarPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLL 130
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 10-132 9.14e-10

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 58.80  E-value: 9.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  10 LQDLAAEHVYTQVNGRRLHCVVAGE--GRPVLLIPGWPQTWYTWRYVMRALAAaGFQAIAVDPPGIGDSDKPAGGYDTGS 87
Cdd:PRK14875 104 EEDAGPAPRKARIGGRTVRYLRLGEgdGTPVVLIHGFGGDLNNWLFNHAALAA-GRPVIALDLPGHGASSKAVGAGSLDE 182

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 727180703  88 IGAALHAMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVL 132
Cdd:PRK14875 183 LAAAVLAFLDALGIERAHLVGHSMGGAVALRLAARAPQRVASLTL 227
PLN02578 PLN02578
hydrolase
 17-184 8.63e-09

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 55.62  E-value: 8.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  17 HVYTQVNGRRLHCVVAGEGRPVLLIPGWPQTWYTWRYVMRALAAAgFQAIAVDPPGIGDSDKPAGGYDTGSIGAALHAMM 96
Cdd:PLN02578  68 YNFWTWRGHKIHYVVQGEGLPIVLIHGFGASAFHWRYNIPELAKK-YKVYALDLLGFGWSDKALIEYDAMVWRDQVADFV 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  97 AQLGHQRYQLVGHDIGMWIGYAMASDFPQAVERLVLTEAV--IPGLAPPPPIFVAPEENIFLWhFMFNQLADLpetltqg 174
Cdd:PLN02578 147 KEVVKEPAVLVGNSLGGFTALSTAVGYPELVAGVALLNSAgqFGSESREKEEAIVVEETVLTR-FVVKPLKEW------- 218

                        170
                 ....*....|
gi 727180703 175 REREYLGYIF 184
Cdd:PLN02578 219 FQRVVLGFLF 228
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 26-136 6.03e-08

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 52.94  E-value: 6.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  26 RLHCVVAGEGRPVLLIPGWPQTWYTWRYVMRALAAAgFQAIAVDPPGIGDSDKPAG-GYDTGSIGAALHAMMAQLGHQRY 104
Cdd:PRK03204  25 RIHYIDEGTGPPILLCHGNPTWSFLYRDIIVALRDR-FRCVAPDYLGFGLSERPSGfGYQIDEHARVIGEFVDHLGLDRY 103

                         90       100       110
                 ....*....|....*....|....*....|..
gi 727180703 105 QLVGHDIGMWIGYAMASDFPQAVERLVLTEAV 136
Cdd:PRK03204 104 LSMGQDWGGPISMAVAVERADRVRGVVLGNTW 135
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 32-143 4.60e-07

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 47.52  E-value: 4.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  32 AGEGRPVLLIPGWPQTWYTWRYVMRALAAAGFQAIAVD-PPGIGDSDKPAggydtGSIGAALHAMMAQLGHQRYQLVGHD 110
Cdd:COG1075    2 AATRYPVVLVHGLGGSAASWAPLAPRLRAAGYPVYALNyPSTNGSIEDSA-----EQLAAFVDAVLAATGAEKVDLVGHS 76

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 727180703 111 IGMWIGYAMASDF--PQAVERLVlteavipGLAPP 143
Cdd:COG1075   77 MGGLVARYYLKRLggAAKVARVV-------TLGTP 104
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 38-285 8.09e-06

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 45.93  E-value: 8.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703   38 VLLIPGWPQTWYTwryvMRALAAAGFQAIAVDPPGIGDSDKPAGGYDTgsiGAALHAMMAQLG-HQRYQLVGHDIGmwiG 116
Cdd:pfam12697   1 VVLVHGAGLSAAP----LAALLAAGVAVLAPDLPGHGSSSPPPLDLAD---LADLAALLDELGaARPVVLVGHSLG---G 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  117 YAMASDFPQAVERLVLTEAVIPGLAPPPPIFVAPEENIFLWhfmfnqladlpetltqgREREYLGYIFNRWSYRRDRVAA 196
Cdd:pfam12697  71 AVALAAAAAALVVGVLVAPLAAPPGLLAALLALLARLGAAL-----------------AAPAWLAAESLARGFLDDLPAD 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  197 KVYIAAYSAPGGLRAGFDYYraipetvrqnRLRAATPLTMPVLTVGAEHATGDAPLTTLRGNARDLRGETVAGCGHFITE 276
Cdd:pfam12697 134 AEWAAALARLAALLAALALL----------PLAAWRDLPVPVLVLAEEDRLVPELAQRLLAALAGARLVVLPGAGHLPLD 203


                  ....*....
gi 727180703  277 EcHEAFIAL 285
Cdd:pfam12697 204 D-PEEVAEA 211
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 26-83 1.14e-05

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 46.41  E-value: 1.14e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  26 RLHCVVAG--EGRPVLLIPGWPQTWYTWRYVMRALAAaGFQAIAVDPPGIGDSDKPAGGY 83
Cdd:PLN03084 116 RWFCVESGsnNNPPVLLIHGFPSQAYSYRKVLPVLSK-NYHAIAFDWLGFGFSDKPQPGY 174
PLN02965 PLN02965
Probable pheophorbidase
 49-170 1.62e-05

Probable pheophorbidase


Pssm-ID: 178549 [Multi-domain]  Cd Length: 255  Bit Score: 45.29  E-value: 1.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  49 YTWRYVMRALAAAGFQAIAVDPPGIGDS-DKPAGGYDTGSIGAALHAMMAQL-GHQRYQLVGHDIGMWIGYAMASDFPQA 126
Cdd:PLN02965  17 WCWYKLATLLDAAGFKSTCVDLTGAGISlTDSNTVSSSDQYNRPLFALLSDLpPDHKVILVGHSIGGGSVTEALCKFTDK 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 727180703 127 VERLVLTEA--VIPGLAPPPPIFVAPEENIFLWHFMFNQLADLPET 170
Cdd:PLN02965  97 ISMAIYVAAamVKPGSIISPRLKNVMEGTEKIWDYTFGEGPDKPPT 142
PRK05855 PRK05855
SDR family oxidoreductase;
14-114 7.56e-04

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 40.73  E-value: 7.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703  14 AAEHVYTQVNGRRLhcVVAGEGRP----VLLIPGWPQTWYTWRYVMRALAAAgFQAIAVDPPGIGDSDKPAG--GYDTGS 87
Cdd:PRK05855   2 QPRRTVVSSDGVRL--AVYEWGDPdrptVVLVHGYPDNHEVWDGVAPLLADR-FRVVAYDVRGAGRSSAPKRtaAYTLAR 78

                         90       100       110
                 ....*....|....*....|....*....|.
gi 727180703  88 IGAALHAMMAQLGHQR-YQLVGHD---IGMW 114
Cdd:PRK05855  79 LADDFAAVIDAVSPDRpVHLLAHDwgsIQGW 109
hydr2_PEP TIGR03101
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha ...
 56-139 2.94e-03

exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 1, TIGR03100) of the same superfamily.


Pssm-ID: 274428  Cd Length: 266  Bit Score: 38.64  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727180703   56 RALAAAGFQAIAVDPPGIGDSdkpAGGYDTGSIG------AALHAMMAQLGHQRYQLVGHDIGMWIGYAMASDFPQAVER 129
Cdd:TIGR03101  50 RAFAAGGFGVLQIDLYGCGDS---AGDFAAARWDvwkedvAAAYRWLIEQGHPPVTLWGLRLGALLALDAANPLAAKCNR 126

                          90
                  ....*....|
gi 727180703  130 LVLTEAVIPG 139
Cdd:TIGR03101 127 LVLWQPVVSG 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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