|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1-1115 |
0e+00 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 2070.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 1 MRLFITLLLGCLLWQPALAAPVPTETQLKQELKQAESSKNaPNQAETTEALQSALNWLTERKESQTRSEQYQRVIDDFPK 80
Cdd:PRK10929 1 MRLIITFLMAWLLSWGAYAATAPDEKQITQELEQAKAAKT-PAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNFPK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 81 MTQELRRQLVLESNKILPNGDDLPAAELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRR 160
Cdd:PRK10929 80 LSAELRQQLNNERDEPRSVPPNMSTDALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 161 LQAQPaNPTTPYAQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQALRNNLNAQRQRE 240
Cdd:PRK10929 160 LQTLG-TPNTPLAQAQLTALQAESAALKALVDELELAQLSANNRQELARLRSELAKKRSQQLDAYLQALRNQLNSQRQRE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 241 AELALEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQWLGSSSAL 320
Cdd:PRK10929 239 AERALESTELLAEQSGDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLREQSQWLGVSNAL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 321 GETLRAQVATLPEMPKPQQLDGDMAQLRVQRLQFENQLEKLSQ-REFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSG 399
Cdd:PRK10929 319 GEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQPQlRQIRQADGQPLTAEQNRILDAQLRTQRELLNSLLSG 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 400 CDTQILELTKLKVANTQLIEALNEIRDATHRYLFWVPDVNPINFSYPLNVAHDLTRVLSLDTLSQLGGAFMMMVTSRETL 479
Cdd:PRK10929 399 GDTLILELTKLKVANSQLEDALKEVNEATHRYLFWVADVSPISLSYPLEIAQDLRRLLSLDTFSQLGKASVMMLTSKETL 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 480 IPIFGALLLVIFSISSRKHYHAFLERASSRVGKVTQDEFFLTVRTVFWSILVAMPLPVLWAALGYGLQSAWNYPVAEAIG 559
Cdd:PRK10929 479 LPLFGALLLVGFSISSRRHYHAFLERSSSRVGKVTQDHFSLTLRTVFWSILVASPLPVLWAALGYGLQNAWPYPLAVAIG 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 560 KGVTATLPILWICMICAAFAHPQGLFIVHFRWPAKQVSRAMRYYKMSIWLIVPLIMALITFDSLKEREFANTLGRLCFIL 639
Cdd:PRK10929 559 DGVTATVPLLWVFMICATFARPNGLFIAHFGWPRERVARAMRYYLLSIGLIVPLIMALITFDNLNDREFSGTLGRLCFIL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 640 LCLALALVTHSLKRAGIPLYLDKNGSGDNMLNSAFWGLLLSAPLLAALASTVGYLTTAQALLARLETSVAIWFLLLVVYH 719
Cdd:PRK10929 639 LCGALSLVTLSLKRAGIPLYLDKEGSGDNIINHALWNLLIGAPLVAALASALGYLATAQALLARLETSVAIWFLLLVVYH 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 720 IIRRWMLIQRRRIAFDRAKQRRADILAQRARGEDETSHTpNSTEGAIDPDDSDFDLDTISAQSLRLVRSILTLIALVSVI 799
Cdd:PRK10929 719 IIRRWMLIQRRRIAFDRAKQRRAEILAQRARGEEEAHHS-SSPEGAIEVEEPVIDLDAISAQSLRLVRSILTLIALLSVI 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 800 VLWSEIHSAFAFLENISLWDVTSTVNGVETAHPITLGAVLIAILVLIITMQLVRNLPALLELAVLQHLDLSPGTGYAITT 879
Cdd:PRK10929 798 VLWSEIHSAFGFLENISLWDVTSTVQGVESLQPITLGSVLIAILVFIITTQLVRNLPALLELALLQHLDLTPGTGYAITT 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 880 ITKYLLLLFGAVLSFAWIGIEWSKLQWVVTALSLGLGFGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKINTR 959
Cdd:PRK10929 878 ITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTR 957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 960 ATTISDWDRKEIIVPNKAFITEQFVNWSLSDTLTRVVLTVPAPGEANSEEVTKILMNAAERCALVLDNPAPEVYLVDLQQ 1039
Cdd:PRK10929 958 ATTISDWDRKEIIVPNKAFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVLDNPAPEVFLVDLQQ 1037
|
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727177714 1040 GIQIFEMRIYAAEMGHRMPLRHEIHQLILAGYREHGITLPYPPFQVRTETLSRltnngRTPPSTPAPNTK-RDAGGL 1115
Cdd:PRK10929 1038 GIQIFELRIYAAEMGHRMPLRHEIHQLILAGFREHGIDMPFPPFQMRLESLGG-----KQTGRTLTSAGKsRTAGSL 1109
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
3-1076 |
4.24e-151 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 480.56 E-value: 4.24e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 3 LFITLLLGCLLWQPALAA---PVPTETQLKQELKQAESSKNA-PNQAETTEALQSALNWLTERKESQTRSEQYQRVIDDF 78
Cdd:PRK11281 13 IAFLFLLLCLSSAFARAAsngDLPTEADVQAQLDALNKQKLLeAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 79 PKMTQELRRQLVLESNKILP----NGDDLPAAELEQQILQTssllleqarlLQQEQDRTREISDSLGQLPQQQTDARRA- 153
Cdd:PRK11281 93 PAKLRQAQAELEALKDDNDEetreTLSTLSLRQLESRLAQT----------LDQLQNAQNDLAEYNSQLVSLQTQPERAq 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 154 --LTEVQRRLQA--------QPANPTTPYAQaaLALLQTEAAArkakvdeleLAQLSANNRQELARMRA--EVYKKRH-- 219
Cdd:PRK11281 163 aaLYANSQRLQQirnllkggKVGGKALRPSQ--RVLLQAEQAL---------LNAQNDLQRKSLEGNTQlqDLLQKQRdy 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 220 --EKIDV---QLQALRNNLNAQRQREAELALEKTEQLAEQNGDLPKS-ISQQLQINRELSAALNSQAQRMDLISsQQRQA 293
Cdd:PRK11281 232 ltARIQRlehQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIQANPlVAQELEINLQLSQRLLKATEKLNTLT-QQNLR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 294 AAQTL-QVRQALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLDGDMAQLRVQrlQFE-NQL-EKLSQ-----RE 365
Cdd:PRK11281 311 VKNWLdRLTQSERNIKEQISVLKGSLLLSRILYQQQQALPSADLIEGLADRIADLRLE--QFEiNQQrDALFQpdayiDK 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 366 FKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQILELTKLKVANTQLIEALNEIRDATHRYLFWVPDVNPINFSY 445
Cdd:PRK11281 389 LEAGHKSEVTDEVRDALLQLLDERRELLDQLNKQLNNQLNLAINLQLNQQQLLSVSDSLQSTLTQQIFWVNSNKPMDLDW 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 446 ----PLNVAHDLTRVLSLDTLSQLGGAFMmmvtsreTLIPIFGALLLVIFSISSRKHY-HAFLERASSRVGKVTQDEFFL 520
Cdd:PRK11281 469 lkafPQALKDQFKSLKITVSFSNLWDGLF-------IALLLFLPLLLIAGLIRWRKKWiKARLQKLAADIGTLKRDSQLH 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 521 TVRTVFWSILVAMPLPVLWAALGYGLQ-SAWNYPvaEAIGKGVTATLPILWICMICAAFAHPQGLFIVHFRWPAKQVSRA 599
Cdd:PRK11281 542 TPKAILITLLLALPVTLIFLAVGLILLtDAFNQS--ELLWSWSLKLALFWLVFATCYRVLRPNGVAERHFGMPKEQVSHF 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 600 MRYYKMSIWLIVPLiMALITFDSLKEREFANTLGRLCFILLCLALALVTHSlkragiPLYLDKNGSGDNMLNSAFWGLLL 679
Cdd:PRK11281 620 RRQIVRLSLALLPL-LFWSVVAELSPLGLADDVIGQAVIIIALALIAFLVW------PLCRESWRDKESHTLRLVVRTVL 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 680 SAPLLAALASTV-GYLTTAQALLARLETSVAIWFLLLVVYHIIRRWMLIQRRRIAFDRAKQRRADILAQRARGEDETSHT 758
Cdd:PRK11281 693 TIAPIALIVLVVlGYYYTALRLIGRLIETLYLLIIWNLLYQTVLRGLSVAARRLAYRRALAKRQNLVKEGAEGAEPVEEP 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 759 PNSTEgaidpddsdfdldTISAQSLRLVRSILTLIALVSVIVLWSEIHSAFAFLENISLWDVTSTVNGVETAHPITLGAV 838
Cdd:PRK11281 773 TLALE-------------QVNQQSLRLTDLLLFALFFVMFYWVWSDLITVFSYLDSITLWHYTTTTAGGAVVESITLGNL 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 839 LIAILVLIITMQLVRNLPALLELAVLQHLDLSPGTGYAITTITKYLLLLFGAVLSFAWIGIEWSKLQWVVTALSLGLGFG 918
Cdd:PRK11281 840 LFALIILVVTYVLVRNLPGLLEVLVLSRLNLRQGTSYAITTLLTYIIIAVGAVTAFSTLGVSWDKLQWLVAALSVGLGFG 919
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 919 MQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKINTRATTISDWDRKEIIVPNKAFITEQFVNWSLSDTLTRVVLT 998
Cdd:PRK11281 920 LQEIFANFVSGLIILFERPVRIGDTVTIGTFSGTVSKIRIRATTITDFDRKEVIVPNKAFVTERLINWSLSDTVTRVVIK 999
|
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727177714 999 VPAPGEANSEEVTKILMNAAERCALVLDNPAPEVYLVDLQQGIQIFEMRIYAAEMGHRMPLRHEIHQLILAGYREHGI 1076
Cdd:PRK11281 1000 VGVAYGSDLEKVRELLLQAATENPRVMKEPEPQVFFLNFGASTLDHELRLYVRELGDRSPTVDELNRRIDRLFRENDI 1077
|
|
| MscS_TM |
pfam12794 |
Mechanosensitive ion channel inner membrane domain 1; The small mechanosensitive channel, MscS, ... |
484-817 |
1.83e-105 |
|
Mechanosensitive ion channel inner membrane domain 1; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this domain is one of the inner membrane domains.
Pssm-ID: 432789 [Multi-domain] Cd Length: 332 Bit Score: 334.18 E-value: 1.83e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 484 GALLLVIFSIS-SRKHYHAFLERASSRVGKVTQDEFFLTVRTVFWSILVAMPLPVLWAALGYGLQ-SAWNYPVAEAIGKG 561
Cdd:pfam12794 1 LLLLLVAGLLLwLRRRLKRRLERLAERVGKVTQDSFLHTLRALLLTLLLALPLPLLLAALGWLLQlSGWATPFSVALGAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 562 VTATLPILWICMICAAFAHPQGLFIVHFRWPAKQVSRAMRYYKMSIWLIVPLIMALITFDSLKEREFANTLGRLCFILLC 641
Cdd:pfam12794 81 LLALALALLVFEFFRRLLRPDGLAIRHFGWPEERVQRLRRQLRWLIWVLVPLVFVLGLAEALPDSLARDVLGRLAFIILM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 642 LALALVTHSLKRAGIPLYLDKNGSGDN-MLNSAFWGLLLSAPLLAALASTVGYLTTAQALLARLETSVAIWFLLLVVYHI 720
Cdd:pfam12794 161 LLLAVFLWRLLRPGRGLYASHLGEGPNsRLRRLWWPLLVLAPLALAVLALLGYYYTALQLLGRLIDSLYLLLGWLLVYAL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 721 IRRWMLIQRRRIAFDRAKQRRADILAQRARGEDETSHTPNSTegaidPDDSDFDLDTISAQSLRLVRSILTLIALVSVIV 800
Cdd:pfam12794 241 ALRWLLVARRRLAYRRAKERRAEALAQRAKEGEEGAEPSESS-----VEEPELDLETISAQSLRLLRLLLLLAFLVGLYW 315
|
330
....*....|....*..
gi 727177714 801 LWSEIHSAFAFLENISL 817
Cdd:pfam12794 316 IWSDLLPAFSYLDNITL 332
|
|
| MscK |
COG3264 |
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis]; |
812-1086 |
8.66e-97 |
|
Small-conductance mechanosensitive channel MscK [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442495 [Multi-domain] Cd Length: 281 Bit Score: 308.67 E-value: 8.66e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 812 LENISLWDVTSTVNGVetahPITLGAVLIAILVLIITMQLVRNLPALLELAVLQHLDLSPGTGYAITTITKYLLLLFGAV 891
Cdd:COG3264 1 MEESALLELLFLIGGI----SISLPNLLLALLILVVTYLLARLLSRLLERRLLRRTRLDPGLRYLISKLIRYLIIVLGLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 892 LSFAWIGIEWSKLQWVVTALSLGLGFGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKINTRATTISDWDRKEI 971
Cdd:COG3264 77 IALSALGIDLTALAALAGALGVGIGFGLQDIVSNFISGLILLFERPFRVGDWIEIGGTEGTVEEIGLRSTRIRTFDGEEV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 972 IVPNKAFITEQFVNWSLSDTLTRVVLTVPAPGEANSEEVTKILMNAAERCALVLDNPAPEVYLVDLQQGIQIFEMRIYAA 1051
Cdd:COG3264 157 IIPNSELITNPVINWSLSDPRRRVEIPVGVAYGSDLEKVRELLLEAAREHPRVLKDPAPSVLFTEFGDSSVNFELRFWVN 236
|
250 260 270
....*....|....*....|....*....|....*
gi 727177714 1052 EMGHRMPLRHEIHQLILAGYREHGITLPYPPFQVR 1086
Cdd:COG3264 237 DPRDRLRVRSDLNEAIKKAFREEGIEIPFPQRDVH 271
|
|
| MS_channel |
pfam00924 |
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss: ... |
878-1076 |
1.05e-57 |
|
Mechanosensitive ion channel; Two members of this protein family: Swiss:Q57634 and Swiss:Q58543 of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.
Pssm-ID: 459999 [Multi-domain] Cd Length: 203 Bit Score: 197.82 E-value: 1.05e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 878 TTITKYLLLLFGAVLSFAWIGIEWSKLQWVVTALSLGLGFGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKIN 957
Cdd:pfam00924 1 KKILKYLIIVVGILIVLSYLGVNVSALLAGLGALGLALGFALQDLVSNLVSGIIILFEKPFKIGDWIEIGDIEGTVEDIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 958 TRATTISDWDRKEIIVPNKAFITEQFVNWSLSDTlTRVVLTVPAPGEANS---EEVTKILMNAAERCALVLDNPAPEVYL 1034
Cdd:pfam00924 81 LRTTTIRTFDGRLVTIPNSSILTSNIINYSRSPT-RRVELSIGVAYSSDPdklEKVIEILKEAAYEHPLVLKDPEPPVVF 159
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 727177714 1035 VDLQQGIQIFEMRIYAAE-MGHRMPLRHEIHQLILAGYREHGI 1076
Cdd:pfam00924 160 GEFGDSSLNFELRVWVKTlPGEYFNVRSELNLRIKKALEENGI 202
|
|
| MscS_porin |
pfam12795 |
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ... |
31-263 |
5.79e-55 |
|
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.
Pssm-ID: 432790 [Multi-domain] Cd Length: 238 Bit Score: 191.36 E-value: 5.79e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 31 ELKQAESSK-NAPNQAETTEALQSALNWLTERKESQTRSEQYQRVIDDFPKMTQELRRQL----VLESNKILPNGDDLPA 105
Cdd:pfam12795 1 KLDELEKAKlDEAAKKKLLQDLQQALSLLDKIDASKQRAAAYQKALDDAPAELRELRQELaalqAKAEAAPKEILASLSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 106 AELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQaQPANPTTPYAQAALALLQTEAA 185
Cdd:pfam12795 81 EELEQRLLQTSAQLQELQNQLAQLNSQLIELQTRPERAQQQLSEARQRLQQIRNRLN-GPAPPGEPLSEAQRWALQAELA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727177714 186 ARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQALRNNLNAQRQREAELALEKTEQLAEQN-GDLPKSIS 263
Cdd:pfam12795 160 ALKAQIDMLEQELLSNNNRQDLLKARRDLLTLRIQRLEQQLQALQELLNEKRLQEAEQAVAQTEQLAEEAaGDHPLVQQ 238
|
|
| MscS |
COG0668 |
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]; |
816-1086 |
1.79e-45 |
|
Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440432 [Multi-domain] Cd Length: 276 Bit Score: 165.43 E-value: 1.79e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 816 SLWDVTSTVNGVETAHPITLGAVLIAILVLIITMQLVRNLPALLELAVLQHLDLSPGTGYaITTITKYLLLLFGAVLSFA 895
Cdd:COG0668 5 QLWSLLGLLLLLGELLLALLPKLLLALLILLIGWLLIRLLRRLIRRLLRRARRDRTLLPL-LRNILKILIVIIAILLILS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 896 WIGIEWSKLQWVVTALSLGLGFGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKINTRATTISDWDRKEIIVPN 975
Cdd:COG0668 84 ILGVNITSLLAGLGAAGLAIGLAAQDLLSNFIAGIFILLERPFRVGDWIEVGGVEGTVEEIGLRSTRLRTLDGRLVTIPN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 976 KAFITEQFVNWSLSDTLtRVVLTVPAPGEANSEEVTKILMNAAERCALVLDNPApEVYLVDLQQGIQIFEMRIYAAEmGH 1055
Cdd:COG0668 164 SKILSSPITNYSRGPTR-RVDVTIGVDYDTDIDKARELLKEILEELPRILKDPA-VVGVTELGDSSVNLRVRAWTKP-GD 240
|
250 260 270
....*....|....*....|....*....|.
gi 727177714 1056 RMPLRHEIHQLILAGYREHGITLPYPPFQVR 1086
Cdd:COG0668 241 YWDVRRDIRERIKAALDEAGIEIPFPTRTVH 271
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
80-423 |
2.80e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 77.85 E-value: 2.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 80 KMTQELRRQLVLESNKILPNGDDLPAAELEQQilqtSSLLLeqarLLQQEQDRTRE-ISD---SLGQLPQQQTDARRALT 155
Cdd:pfam15921 224 KILRELDTEISYLKGRIFPVEDQLEALKSESQ----NKIEL----LLQQHQDRIEQlISEhevEITGLTEKASSARSQAN 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 156 EVQRRL---QAQPANPTTPYA------QAALALLQTEAAARKA----KVDELELAQLSANNRQELARMRAEVYKKRHEKI 222
Cdd:pfam15921 296 SIQSQLeiiQEQARNQNSMYMrqlsdlESTVSQLRSELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNL 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 223 DVQLQALRNNLNaqrQREAELALEKTEQLAEQNGDLPKSISQQlQINRELSAAlNSQAQRMD-LISSQQRQAAAqtlQVR 301
Cdd:pfam15921 376 DDQLQKLLADLH---KREKELSLEKEQNKRLWDRDTGNSITID-HLRRELDDR-NMEVQRLEaLLKAMKSECQG---QME 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 302 QALSTIIEQAQWLGSSSalgeTLRAQVATLPEMpkpqqLDGDMAQLRVQRLQFENQLEKLSqrefkrdDGSALTNQEQRI 381
Cdd:pfam15921 448 RQMAAIQGKNESLEKVS----SLTAQLESTKEM-----LRKVVEELTAKKMTLESSERTVS-------DLTASLQEKERA 511
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 727177714 382 VDAqlrTQRElLNSLLSGCDTQILELTKLKVANTQLIEALNE 423
Cdd:pfam15921 512 IEA---TNAE-ITKLRSRVDLKLQELQHLKNEGDHLRNVQTE 549
|
|
| PRK10334 |
PRK10334 |
small-conductance mechanosensitive channel MscS; |
838-1085 |
1.10e-12 |
|
small-conductance mechanosensitive channel MscS;
Pssm-ID: 182386 [Multi-domain] Cd Length: 286 Bit Score: 69.95 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 838 VLIAILVLIITMQLVRNLP-ALLELAVLQHLDLSpgTGYAITTITKYLLLLFGAVLSFAWIGIEWSKLQWVVTALSLGLG 916
Cdd:PRK10334 31 IVAALAIIIVGLIIARMISnAVNRLMISRKIDAT--VADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGAAGLAVG 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 917 FGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKINTRATTISDWDRKEIIVPNKAFITEQFVNWSlSDTLTRVV 996
Cdd:PRK10334 109 LALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADGKIIVIPNGKIIAGNIINFS-REPVRRNE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 997 LTVPAPGEANSEEVTKILMNAAERCALVLDNPAPEVYLVDLQQGIQIFEMRIYaAEMGHRMPLRHEIHQLILAGYREHGI 1076
Cdd:PRK10334 188 FIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNELGASSINFVVRVW-SNSGDLQNVYWDVLERIKREFDAAGI 266
|
....*....
gi 727177714 1077 TLPYPPFQV 1085
Cdd:PRK10334 267 SFPYPQMDV 275
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
101-425 |
1.97e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.88 E-value: 1.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 101 DDLpAAELEQQI--LQTSSLLLEQARLLQQEQDRTR--EISDSLGQLPQQQTDARRALTEVQRRLQAqpanpttpyAQAA 176
Cdd:COG1196 192 EDI-LGELERQLepLERQAEKAERYRELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEE---------LEAE 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 177 LALLQTEAAARKAKVDELELAQLSANNRQELARMRAEvykkRHEKIDVQLQALRNNLNAQRQREAELALEKTEQLAEQNG 256
Cdd:COG1196 262 LAELEAELEELRLELEELELELEEAQAEEYELLAELA----RLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 257 DLpksisqqlqinRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQwlgssSALGETLRAQVATLPEMPK 336
Cdd:COG1196 338 EL-----------EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-----ELAEELLEALRAAAELAAQ 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 337 PQQLDGDMAQLRVQRLQFENQLEKLSQREFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQILELTKLKVANTQ 416
Cdd:COG1196 402 LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481
|
....*....
gi 727177714 417 LIEALNEIR 425
Cdd:COG1196 482 LLEELAEAA 490
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
58-363 |
2.07e-09 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 61.89 E-value: 2.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 58 LTERKESQTRSEQ-YQRVIDDFPKMTQELRRQlvlesNKILPNGDDLpaAELEQQILQTSSLLLEQARLLQQEQDRTREI 136
Cdd:COG3096 315 LEELSARESDLEQdYQAASDHLNLVQTALRQQ-----EKIERYQEDL--EELTERLEEQEEVVEEAAEQLAEAEARLEAA 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 137 SDSLGQLPQQQTDARRALTEVQRR-LQAQPANPTTPYAQAALAL-------LQTEAAARKAKVDELELAQLSANNRQELA 208
Cdd:COG3096 388 EEEVDSLKSQLADYQQALDVQQTRaIQYQQAVQALEKARALCGLpdltpenAEDYLAAFRAKEQQATEEVLELEQKLSVA 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 209 RM--------------------RAEVYKKRHEKI----DVQLQALRNNLNAQRQREAELALEKTEQLAEQNGDLPKSISQ 264
Cdd:COG3096 468 DAarrqfekayelvckiageveRSQAWQTARELLrryrSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQ 547
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 265 QLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQ--------WLGSSSALgETLRAQVATlpEMPK 336
Cdd:COG3096 548 QLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKelaarapaWLAAQDAL-ERLREQSGE--ALAD 624
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 727177714 337 PQQLDGDMAQ--------------LRVQRLQFENQLEKLSQ 363
Cdd:COG3096 625 SQEVTAAMQQllerereatverdeLAARKQALESQIERLSQ 665
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
18-365 |
2.88e-09 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 61.51 E-value: 2.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 18 LAAPVPTETQLKQELKQA----ESSKNAPNQAETTEALQSALNWLTERKESQT--RSEQYQRVIddfpkmtqELRRQLVL 91
Cdd:PRK04863 316 LAELNEAESDLEQDYQAAsdhlNLVQTALRQQEKIERYQADLEELEERLEEQNevVEEADEQQE--------ENEARAEA 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 92 ESNKIlpngDDLpAAELE--QQ---ILQTSSL-------LLEQARLLQQEQDRTRE-ISDSLGQLPQQQTDARRALTEVQ 158
Cdd:PRK04863 388 AEEEV----DEL-KSQLAdyQQaldVQQTRAIqyqqavqALERAKQLCGLPDLTADnAEDWLEEFQAKEQEATEELLSLE 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 159 RRLQ-AQPANptTPYAQAAlallqteAAARKAkVDELELAQLSANNRQELARMRAEVYkkrhekIDVQLQALRNNLNAQR 237
Cdd:PRK04863 463 QKLSvAQAAH--SQFEQAY-------QLVRKI-AGEVSRSEAWDVARELLRRLREQRH------LAEQLQQLRMRLSELE 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 238 QReaelaLEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQ----- 312
Cdd:PRK04863 527 QR-----LRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQrlaar 601
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 313 ---WLGSSSALgETLRAQVATlpEMPKPQQLDGDMAQL--------------RVQRLQFENQLEKLSQRE 365
Cdd:PRK04863 602 apaWLAAQDAL-ARLREQSGE--EFEDSQDVTEYMQQLlerereltverdelAARKQALDEEIERLSQPG 668
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
106-365 |
1.15e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 106 AELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQ---RRLQAQPANPTTPYAQAALAL--L 180
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRkdlARLEAEVEQLEERIAQLSKELteL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 181 QTEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQALRNNLNAQRQREAELAlEKTEQLAEQNGDLPK 260
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-ERLESLERRIAATER 838
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 261 SI---SQQLQINRELSAALNSQaqrmdlISSQQRQAAAQTLQVRQALSTIIEQAQWLGSSSALGETLRAQVATLPEmpKP 337
Cdd:TIGR02168 839 RLedlEEQIEELSEDIESLAAE------IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES--KR 910
|
250 260
....*....|....*....|....*...
gi 727177714 338 QQLDGDMAQLRVQRLQFENQLEKLSQRE 365
Cdd:TIGR02168 911 SELRRELEELREKLAQLELRLEGLEVRI 938
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
69-404 |
8.68e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.67 E-value: 8.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 69 EQYQRVIDDFPKMTQELRRQLVlESNKIlpngDDLPAAELEQQILQTSSLLLEqarlLQQEQD-----RTREisdslgql 143
Cdd:pfam15921 74 EHIERVLEEYSHQVKDLQRRLN-ESNEL----HEKQKFYLRQSVIDLQTKLQE----MQMERDamadiRRRE-------- 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 144 PQQQTDARRALTEVQRRLQAQPA-------NPTTPYAQAALALLQTEAAARKAKVDELELAQLSANNRQE---------- 206
Cdd:pfam15921 137 SQSQEDLRNQLQNTVHELEAAKClkedmleDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEhdsmstmhfr 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 207 -----LARMRAEV------YKKRHEKIDVQLQALRnnlnAQRQREAELALE----KTEQLAEQNGDLPKSISQQLQINRE 271
Cdd:pfam15921 217 slgsaISKILRELdteisyLKGRIFPVEDQLEALK----SESQNKIELLLQqhqdRIEQLISEHEVEITGLTEKASSARS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 272 LSAALNSQaqrMDLISSQQRQAAAQTLQVRQALSTIIEQAQwlgssSALGETLRAQVATLPEMPKPQQL-DGDMAQLRVQ 350
Cdd:pfam15921 293 QANSIQSQ---LEIIQEQARNQNSMYMRQLSDLESTVSQLR-----SELREAKRMYEDKIEELEKQLVLaNSELTEARTE 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 351 RLQF-------ENQLEKL-----------------SQREFKRDDGSALTNQEQR--IVDAQLRTQR--ELLNSLLSGCDT 402
Cdd:pfam15921 365 RDQFsqesgnlDDQLQKLladlhkrekelslekeqNKRLWDRDTGNSITIDHLRreLDDRNMEVQRleALLKAMKSECQG 444
|
..
gi 727177714 403 QI 404
Cdd:pfam15921 445 QM 446
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
16-368 |
1.30e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.90 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 16 PALAAPVPTETQ-LKQELKQAESSKNAPNQAETTEALQSALNWLTERKESQTRSE-----------QYQRVI------DD 77
Cdd:pfam17380 213 IQMSTVAPKEVQgMPHTLAPYEKMERRKESFNLAEDVTTMTPEYTVRYNGQTMTEneflnqllhivQHQKAVserqqqEK 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 78 FPKMTQELRRQ------LVLESNKILPNGDDLPAAELEQQIL---QTSSLLLEQARLLQ--QEQDRTREisdsLGQLPQQ 146
Cdd:pfam17380 293 FEKMEQERLRQekeekaREVERRRKLEEAEKARQAEMDRQAAiyaEQERMAMERERELEriRQEERKRE----LERIRQE 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 147 QTDARRALTEVQRRLQAQpanpttpYAQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQL 226
Cdd:pfam17380 369 EIAMEISRMRELERLQME-------RQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 227 QALRNNLNAQRQREAELAlEKTEQLAEQNGDLPKsisQQLQINRELSAALNSQAQRMDLISSQ---QRQAAAQTLQVRQA 303
Cdd:pfam17380 442 EERAREMERVRLEEQERQ-QQVERLRQQEEERKR---KKLELEKEKRDRKRAEEQRRKILEKEleeRKQAMIEEERKRKL 517
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 304 LSTIIEQAQwlgssSALGETLRAQVA-----TLPEMPKPQQLDGDMAQLRVQRLQFEnQLEKlsQREFKR 368
Cdd:pfam17380 518 LEKEMEERQ-----KAIYEEERRREAeeerrKQQEMEERRRIQEQMRKATEERSRLE-AMER--EREMMR 579
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
16-254 |
2.92e-07 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 54.57 E-value: 2.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 16 PALAAPVPTETQLKQE----------LKQAESSKNAPNQAETTEALQSALNWLTERKESQTRSEQYQRVIDDFPKMTQEL 85
Cdd:pfam15709 299 PTQTFVVTGNMESEEErseedpskalLEKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREEL 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 86 RR--QLVLESNKilpngddLPAAELEQQILQTSSLLLEQARLLQQEQDRTReisdslgqlpQQQTDARRALTEVQRRLQA 163
Cdd:pfam15709 379 ELeqQRRFEEIR-------LRKQRLEEERQRQEEEERKQRLQLQAAQERAR----------QQQEEFRRKLQELQRKKQQ 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 164 QPANpttpyaqaalallqtEAAARKAKVDELE---------LAQLSANNRQELARMRAEVYKKRhekidvQLQAlrnnlN 234
Cdd:pfam15709 442 EEAE---------------RAEAEKQRQKELEmqlaeeqkrLMEMAEEERLEYQRQKQEAEEKA------RLEA-----E 495
|
250 260
....*....|....*....|...
gi 727177714 235 AQRQRE---AELALEKTEQLAEQ 254
Cdd:pfam15709 496 ERRQKEeeaARLALEEAMKQAQE 518
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
28-220 |
5.26e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 5.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 28 LKQELKQAESSKNApnQAETTEALQSALNWLTERKESQTRSEQYQRVIDDFP---KMTQELRRQL--VLESNkilpngDD 102
Cdd:COG4913 615 LEAELAELEEELAE--AEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaeREIAELEAELerLDASS------DD 686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 103 LpaAELEQQilqtssllLEQARLLQQEQDRTR-EISDSLGQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQ 181
Cdd:COG4913 687 L--AALEEQ--------LEELEAELEELEEELdELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFA 756
|
170 180 190
....*....|....*....|....*....|....*....
gi 727177714 182 TEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHE 220
Cdd:COG4913 757 AALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
105-348 |
6.68e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 6.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAqpanpttpyAQAALALLQTEA 184
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA---------LEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 185 AARKAKVDELelaqlsannRQELARMRAEVYK-KRHEKIDVQL------QALRNN-----LNAQRQREAELALEKTEQLA 252
Cdd:COG4942 93 AELRAELEAQ---------KEELAELLRALYRlGRQPPLALLLspedflDAVRRLqylkyLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 253 EQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQWLgssSALGETLRAQVATLP 332
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAA 240
|
250
....*....|....*.
gi 727177714 333 EMPKPQQLDGDMAQLR 348
Cdd:COG4942 241 ERTPAAGFAALKGKLP 256
|
|
| TolA |
COG3064 |
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis]; |
121-543 |
1.35e-06 |
|
Membrane protein TolA involved in colicin uptake [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442298 [Multi-domain] Cd Length: 485 Bit Score: 52.35 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 121 EQARLLQQEQDRTREisDSLGQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALA--------LLQTEAAARKAKvd 192
Cdd:COG3064 55 EEAREAKAEAEQRAA--ELAAEAAKKLAEAEKAAAEAEKKAAAEKAKAAKEAEAAAAAekaaaaaeKEKAEEAKRKAE-- 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 193 elELAQLSANNRQELARMR----AEVYKKRHEKIDVQLQALRNNLNAQRQREAELALEKTEQLAEQNGDLPKSISQQLQI 268
Cdd:COG3064 131 --EEAKRKAEEERKAAEAEaaakAEAEAARAAAAAAAAAAAAAARAAAGAAAALVAAAAAAVEAADTAAAAAAALAAAAA 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 269 NRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLDGDMAQLR 348
Cdd:COG3064 209 AAAADAALLALAVAARAAAASREAALAAVEATEEAALGGAEEAADLAAVGVLGAALAAAAAGAAALSSGLVVVAAALAGL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 349 VQRLQFENQLEKLSQ-REFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQILELTKLKVANTQLIEALNEIRDA 427
Cdd:COG3064 289 AAAAAGLVLDDSAALaAELLGAVAAEEAVLAAAAAAGALVVRGGGAASLEAALSLLAAGAAAAAAGAGALATGALGDALA 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 428 ---THRYLFWVPDVNPINFSYPLNVAHDLTRVLSLDTLSQLGGAFMMMVTSRETLIPIFGALLLVIFSISSRKHYHAFLE 504
Cdd:COG3064 369 aeaAGALLLGKLADVEEAAGAGILAAAGGGGLLGLRLDLGAALLEAASAVELRVLLALAGAAGAVVALLVKLVADLAGGL 448
|
410 420 430
....*....|....*....|....*....|....*....
gi 727177714 505 RASSRVGKVTQDEffLTVRTVFWSILVAMPLPVLWAALG 543
Cdd:COG3064 449 VGIGKALTGDADA--LLGILKAVALDGGAVLADLLLLGG 485
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
24-388 |
1.37e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.74 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 24 TETQLKQELKQAES-SKNAPNQAETTEALQSALNwlTERKESQTRSEQYQRVIDDFPKMTQELRRQLVLESNKILPNGDD 102
Cdd:TIGR00606 689 TEAELQEFISDLQSkLRLAPDKLKSTESELKKKE--KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 103 LpaAELEQQI------LQTSSLLLEQARLLQQEQDRTREISDSLGQLPQ--QQTDARRALTEVQRRLQ------------ 162
Cdd:TIGR00606 767 I--EEQETLLgtimpeEESAKVCLTDVTIMERFQMELKDVERKIAQQAAklQGSDLDRTVQQVNQEKQekqheldtvvsk 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 163 -------AQPANPTTPYAQAALALLQTE------AAARKAKVDElELAQLSANNRQ---ELARMRAEV-----YKKRHEK 221
Cdd:TIGR00606 845 ielnrklIQDQQEQIQHLKSKTNELKSEklqigtNLQRRQQFEE-QLVELSTEVQSlirEIKDAKEQDspletFLEKDQQ 923
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 222 IDVQLQALRNNLNAQRQREAELALEKTEQLAEQNGDLPKSIS-----QQLQINRELS---AALNSQAQRMDLISSQQRQa 293
Cdd:TIGR00606 924 EKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQdgkddYLKQKETELNtvnAQLEECEKHQEKINEDMRL- 1002
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 294 aaqtlqVRQALSTIIEQAQWLGSSSalgeTLRAQVATLPEMPK-PQQLDGDMAQLRVqrLQFENQLEKLSQ--REFKRDD 370
Cdd:TIGR00606 1003 ------MRQDIDTQKIQERWLQDNL----TLRKRENELKEVEEeLKQHLKEMGQMQV--LQMKQEHQKLEEniDLIKRNH 1070
|
410 420
....*....|....*....|...
gi 727177714 371 GSALTNQ-----EQRIVDAQLRT 388
Cdd:TIGR00606 1071 VLALGRQkgyekEIKHFKKELRE 1093
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
105-427 |
1.47e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQI--LQTSSLLLEQARLLQqEQDRTREISDSLGQLpQQQTDARRALTEVQRRLQAQpanpttpyaqaaLALLQT 182
Cdd:TIGR02168 195 LNELERQLksLERQAEKAERYKELK-AELRELELALLVLRL-EELREELEELQEELKEAEEE------------LEELTA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 183 EAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQALRnnlnaQRQREAElalEKTEQLAEQNGDLPKSI 262
Cdd:TIGR02168 261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR-----ERLANLE---RQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 263 SQQLQINRELSAALNSQAQRMDLISSQQRQAAAQtlqvRQALSTIIEQAQwlgsssALGETLRAQVAtlpempkpqQLDG 342
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELE------EQLETLRSKVA---------QLEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 343 DMAQLRVQRLQFENQLEKLSQRefkrddgsaLTNQEQRIVDAQLRTQRELLNSLLSGCDTQILELTKLKVANTQLIEALN 422
Cdd:TIGR02168 394 QIASLNNEIERLEARLERLEDR---------RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE 464
|
....*
gi 727177714 423 EIRDA 427
Cdd:TIGR02168 465 ELREE 469
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
84-403 |
1.59e-06 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 52.45 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 84 ELRRQLVLESNK--ILPNGDDLPAAELEQQILQTSSLLLE-----QARLLQQEQDRTRE--ISDSLGQLPQQQTDARRAL 154
Cdd:pfam07111 342 ELQEQVTSQSQEqaILQRALQDKAAEVEVERMSAKGLQMElsraqEARRRQQQQTASAEeqLKFVVNAMSSTQIWLETTM 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 155 TEVQRRLQAQPA-NPTTPYA-------------QAALALLQTEA-----AARKAKVD-ELELAQLsannRQELARMRAEV 214
Cdd:pfam07111 422 TRVEQAVARIPSlSNRLSYAvrkvhtikglmarKVALAQLRQEScppppPAPPVDADlSLELEQL----REERNRLDAEL 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 215 YKKRHeKIDVQLQALRNNLNAQRQREAELAlEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAA 294
Cdd:pfam07111 498 QLSAH-LIQQEVGRAREQGEAERQQLSEVA-QQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIY 575
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 295 AQTLQVRQALSTIIEQAQWLGSSSALGETLRAQ---VATLPEMPKPQQLDGDMAQlRVQRLQFENQLE---KLSQR--EF 366
Cdd:pfam07111 576 GQALQEKVAEVETRLREQLSDTKRRLNEARREQakaVVSLRQIQHRATQEKERNQ-ELRRLQDEARKEegqRLARRvqEL 654
|
330 340 350
....*....|....*....|....*....|....*..
gi 727177714 367 KRDDGSALTNQEQRIVDAQLRTQReLLNSLLSGCDTQ 403
Cdd:pfam07111 655 ERDKNLMLATLQQEGLLSRYKQQR-LLAVLPSGLDKK 690
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
28-416 |
2.11e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.28 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 28 LKQELKQAEssknapnqaETTEALQSALNWLTERKESQTRSEQYQRVIDDFPKMTQELRRQLVLESN------------K 95
Cdd:TIGR00618 224 LEKELKHLR---------EALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEEtqerinrarkaaP 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 96 ILPNGDDLpaAELEQQI------LQTSSLLLEQAR-----LLQQEQDrtREISDSLGQLPQQQTDARRALTEVQRRLQAQ 164
Cdd:TIGR00618 295 LAAHIKAV--TQIEQQAqrihteLQSKMRSRAKLLmkraaHVKQQSS--IEEQRRLLQTLHSQEIHIRDAHEVATSIREI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 165 PANPTT------PYAQAALALLQTE--AAARKAKVDELE---LAQLSANN--RQELARMRAEVyKKRHEKIDVQLQALRN 231
Cdd:TIGR00618 371 SCQQHTltqhihTLQQQKTTLTQKLqsLCKELDILQREQatiDTRTSAFRdlQGQLAHAKKQQ-ELQQRYAELCAAAITC 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 232 NLNAQRQREAEL--ALEKTEQLAEQNGDLPKSISQQLQINRElsaalnsQAQRMDLISSQQRQAAAQTLQVRQALSTIIE 309
Cdd:TIGR00618 450 TAQCEKLEKIHLqeSAQSLKEREQQLQTKEQIHLQETRKKAV-------VLARLLELQEEPCPLCGSCIHPNPARQDIDN 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 310 qaqwLGSSSALGETLRAQVATLPEMPKpqQLDGDMAQLRVQRLQFENQLEKLSQREFK--------RDDGSALTNQEQRI 381
Cdd:TIGR00618 523 ----PGPLTRRMQRGEQTYAQLETSEE--DVYHQLTSERKQRASLKEQMQEIQQSFSIltqcdnrsKEDIPNLQNITVRL 596
|
410 420 430
....*....|....*....|....*....|....*...
gi 727177714 382 ---VDAQLRTQRELLnsllsgCDTQILELTKLKVANTQ 416
Cdd:TIGR00618 597 qdlTEKLSEAEDMLA------CEQHALLRKLQPEQDLQ 628
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
60-391 |
2.61e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.89 E-value: 2.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 60 ERKE---SQTRSEQYQRVIDDFPKMTQELRRQLVLESNKILPNGDDLPA-AELEQQILQTSSLLLEQARLLQQEQDRTRE 135
Cdd:TIGR00618 164 EKKEllmNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCmPDTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 136 ISDSLGQLPQQQTDARRALTEVQRRLQAqpanpttpyaqaalalLQTEAAarkakvdELELAQLSANNRQELARMRAEVy 215
Cdd:TIGR00618 244 YLTQKREAQEEQLKKQQLLKQLRARIEE----------------LRAQEA-------VLEETQERINRARKAAPLAAHI- 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 216 kKRHEKIDVQLQALRNNLNAQ-RQREAELALEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAA 294
Cdd:TIGR00618 300 -KAVTQIEQQAQRIHTELQSKmRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLT 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 295 AQTLQVRQALSTIIEQAQwlgSSSALGETLRAQVAT-LPEMPKPQQLDGDMAQLR-----------VQRLQFENQLEKLS 362
Cdd:TIGR00618 379 QHIHTLQQQKTTLTQKLQ---SLCKELDILQREQATiDTRTSAFRDLQGQLAHAKkqqelqqryaeLCAAAITCTAQCEK 455
|
330 340 350
....*....|....*....|....*....|
gi 727177714 363 QRE-FKRDDGSALTNQEQRIVDAQLRTQRE 391
Cdd:TIGR00618 456 LEKiHLQESAQSLKEREQQLQTKEQIHLQE 485
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
108-335 |
9.48e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.63 E-value: 9.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 108 LEQQILQTSSLLLEQARLLQ--QEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAqpanpttpyAQAALALLQTEAA 185
Cdd:COG3206 180 LEEQLPELRKELEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAE---------AEARLAALRAQLG 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 186 ARKAKVDELELAQLSANNRQELARMRAEV------YKKRHEKIdVQLQALRNNLNAQRQREAELALEKTEQLAEQNGDLP 259
Cdd:COG3206 251 SGPDALPELLQSPVIQQLRAQLAELEAELaelsarYTPNHPDV-IALRAQIAALRAQLQQEAQRILASLEAELEALQARE 329
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727177714 260 KSISQQLQINRELSAALNSQAQRMdliSSQQRQAAAQtlqvRQALSTIIEQAQWLGSSSALGETlRAQV---ATLPEMP 335
Cdd:COG3206 330 ASLQAQLAQLEARLAELPELEAEL---RRLEREVEVA----RELYESLLQRLEEARLAEALTVG-NVRVidpAVVPLKP 400
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
144-373 |
1.18e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 144 PQQQTDARRALTEVQRRLQAQpanpttpyaQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKID 223
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAEL---------EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 224 VQLQALRNNLNAQRQREAEL--ALEKTEQL--------AEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQA 293
Cdd:COG4942 90 KEIAELRAELEAQKEELAELlrALYRLGRQpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 294 AAQTLQVRQALSTIIEQAQWLGSSSALGETLRAQVATlpempKPQQLDGDMAQLRVQRLQFENQLEKLSQREFKRDDGSA 373
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKAERQKLLARLEK-----ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
175-413 |
1.51e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 175 AALALLQTEAAARKAKVDELELAQLsannRQELARMRAEV--YKKRHEKIDVQLQALRNNLNAQRQ--REAELALEKTEQ 250
Cdd:COG4942 8 ALLLALAAAAQADAAAEAEAELEQL----QQEIAELEKELaaLKKEEKALLKQLAALERRIAALARriRALEQELAALEA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 251 LAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQ----RQAAAQTLQVRQALSTIIEQAQwlgsssALGETLRA 326
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARR------EQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 327 QVATLPEmpKPQQLDGDMAQLRVQRLQFENQLEKLSQREFKRDDGSA-----LTNQEQRIvdAQLRTQRELLNSLLSGCD 401
Cdd:COG4942 158 DLAELAA--LRAELEAERAELEALLAELEEERAALEALKAERQKLLArlekeLAELAAEL--AELQQEAEELEALIARLE 233
|
250
....*....|..
gi 727177714 402 TQILELTKLKVA 413
Cdd:COG4942 234 AEAAAAAERTPA 245
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
186-427 |
2.83e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.51 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 186 ARKAKVDELE-----LAQLSANNRQELARMRAEV--YKKRHEKIDVQLQALRNNLNAQRQrEAELALEKTEQLAEQNGDL 258
Cdd:TIGR02168 674 ERRREIEELEekieeLEEKIAELEKALAELRKELeeLEEELEQLRKELEELSRQISALRK-DLARLEAEVEQLEERIAQL 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 259 PKSISQQLQINRELSAALNsqaqrmdlissQQRQAAAQTLQVRQALSTIIEQAQwlGSSSALGETLRAQVATLpempkpQ 338
Cdd:TIGR02168 753 SKELTELEAEIEELEERLE-----------EAEEELAEAEAEIEELEAQIEQLK--EELKALREALDELRAEL------T 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 339 QLDGDMAQLRVQRLQFENQLEKLSQRefkrddgsaLTNQEQRIvdAQLRTQRELLNSLLSGCDTQI----LELTKLKVAN 414
Cdd:TIGR02168 814 LLNEEAANLRERLESLERRIAATERR---------LEDLEEQI--EELSEDIESLAAEIEELEELIeeleSELEALLNER 882
|
250
....*....|...
gi 727177714 415 TQLIEALNEIRDA 427
Cdd:TIGR02168 883 ASLEEALALLRSE 895
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
120-430 |
3.11e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.20 E-value: 3.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 120 LEQARLLQQEQDRTREIsdslgqlpqqqtDARRALTEVQRRLQAQPANPTTPYAqaalallqteaaarkakvdelELAQL 199
Cdd:pfam17380 296 MEQERLRQEKEEKAREV------------ERRRKLEEAEKARQAEMDRQAAIYA---------------------EQERM 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 200 SANNRQELARMRAEVYKKRHEKIDVQLQALRnnlnAQRQREAE-LALEKTEQLAEQNGDLPKSISQQLQiNRELSAALNS 278
Cdd:pfam17380 343 AMERERELERIRQEERKRELERIRQEEIAME----ISRMRELErLQMERQQKNERVRQELEAARKVKIL-EEERQRKIQQ 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 279 QAQRMDLISSQQRQAAAQTLQVRqalstiieqaqwlgsssalgETLRAQvatlpempkpqqldgDMAQLRVQRLQFENQL 358
Cdd:pfam17380 418 QKVEMEQIRAEQEEARQREVRRL--------------------EEERAR---------------EMERVRLEEQERQQQV 462
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 727177714 359 EKLSQREFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQIL-ELTKLKVANTQLIEALNEIRDATHR 430
Cdd:pfam17380 463 ERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIeEERKRKLLEKEMEERQKAIYEEERR 535
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
105-257 |
5.94e-05 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 46.72 E-value: 5.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQILQtsslllEQARLLQQEQDRTREisdsLGQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQTEA 184
Cdd:PRK09510 89 AEELQQKQAA------EQERLKQLEKERLAA----QEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEAKRAAA 158
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 727177714 185 AARKAKVDELELAQLSANNRQElarmrAEVYKKRHEKIDVQLQALrnnlnAQRQREAElALEKTEQLAEQNGD 257
Cdd:PRK09510 159 AAKKAAAEAKKKAEAEAAKKAA-----AEAKKKAEAEAAAKAAAE-----AKKKAEAE-AKKKAAAEAKKKAA 220
|
|
| PRK11465 |
PRK11465 |
putative mechanosensitive channel protein; Provisional |
877-960 |
7.22e-05 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 183147 [Multi-domain] Cd Length: 741 Bit Score: 47.08 E-value: 7.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 877 ITTITKYLLLlfgavlsfAWIGIEWSKLQWVVTALSLGLGFGMQEIFSNFISGLIILFEKPIRIGDTVTIRNLTGTVTKI 956
Cdd:PRK11465 521 ISTITIMIVL--------SEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERM 592
|
....
gi 727177714 957 NTRA 960
Cdd:PRK11465 593 SIRS 596
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
27-430 |
8.71e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 8.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 27 QLKQELKQAESSKNAPNQAETT-EALQSALNWL-TERKESQTRSEQYQRVIDDFP--KMTQELRRQLVLESNKIlpngdd 102
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEElEELEEELEELeAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERL------ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 103 lpaAELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLP----QQQTDARRALTEVQRRLQAqpanpttpyAQAALA 178
Cdd:COG4717 149 ---EELEERLEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQRLAE---------LEEELE 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 179 LLQTEAAARKAKVDELELAQLSANNRQELARMR-------------------AEVYKKRHEKIDVQLQAL--------RN 231
Cdd:COG4717 217 EAQEELEELEEELEQLENELEAAALEERLKEARlllliaaallallglggslLSLILTIAGVLFLVLGLLallflllaRE 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 232 NLNAQRQREAELALEKTEQLAEQN-----GDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQ---- 302
Cdd:COG4717 297 KASLGKEAEELQALPALEELEEEEleellAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaall 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 303 ---------ALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLDGDMAQLRVQRLQFENQLEKLS-QREFKRDDGS 372
Cdd:COG4717 377 aeagvedeeELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEeELEELREELA 456
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 727177714 373 ALTNQEQRIVD----AQLRTQRELLNSllsgcdtQILELTKLKVANTQLIEALNEIRDATHR 430
Cdd:COG4717 457 ELEAELEQLEEdgelAELLQELEELKA-------ELRELAEEWAALKLALELLEEAREEYRE 511
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
83-277 |
1.12e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 83 QELRRQL-VLEsnKILPNGDDLPAAELEQQILQTSSLLL------EQARLLQQEQDRTREISDSLGQ----LPQQQTDAR 151
Cdd:COG4913 245 EDAREQIeLLE--PIRELAERYAAARERLAELEYLRAALrlwfaqRRLELLEAELEELRAELARLEAelerLEARLDALR 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 152 RALTEVQRRLQAQPANPTTPyAQAALALLQTEAAARKAKVDELE--LAQL---SANNRQELARMRAEV------YKKRHE 220
Cdd:COG4913 323 EELDELEAQIRGNGGDRLEQ-LEREIERLERELEERERRRARLEalLAALglpLPASAEEFAALRAEAaalleaLEEELE 401
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 727177714 221 KIDVQLQALRNNLNAQRQREAELALEKtEQLAEQNGDLPksiSQQLQINRELSAALN 277
Cdd:COG4913 402 ALEEALAEAEAALRDLRRELRELEAEI-ASLERRKSNIP---ARLLALRDALAEALG 454
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
131-398 |
1.51e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.06 E-value: 1.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 131 DRTREISDSLGQLpqqqTDARRALTEVQRRLQAqpanpttpyaqaaLALLQTEAAARKAKVDELELAQ-LSANNRQELAR 209
Cdd:COG4913 225 EAADALVEHFDDL----ERAHEALEDAREQIEL-------------LEPIRELAERYAAARERLAELEyLRAALRLWFAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 210 MRAEVYKKRHEKIDVQLQALRNNLNAQRQREAELALEKTE---QLAEQNGDLPKSISQQLqinRELSAALNSQAQRmdli 286
Cdd:COG4913 288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDEleaQIRGNGGDRLEQLEREI---ERLERELEERERR---- 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 287 sSQQRQAAAQTLQVRQALStiieQAQWLgsssALGETLRAQVATLPEMPKpqQLDGDMAQLRVQRLQFENQLEKLSQRef 366
Cdd:COG4913 361 -RARLEALLAALGLPLPAS----AEEFA----ALRAEAAALLEALEEELE--ALEEALAEAEAALRDLRRELRELEAE-- 427
|
250 260 270
....*....|....*....|....*....|....
gi 727177714 367 krddgsaLTNQEQRI--VDAQLRTQRELLNSLLS 398
Cdd:COG4913 428 -------IASLERRKsnIPARLLALRDALAEALG 454
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
36-395 |
1.64e-04 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 45.95 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 36 ESSKNAPNQAETTEALQSALNWLTErkesqtrsEQYQRVIDDFPKMTQELRRQLVlesnkilpngddlpaaelEQQILQT 115
Cdd:PRK10246 191 EQHKSARTELEKLQAQASGVALLTP--------EQVQSLTASLQVLTDEEKQLLT------------------AQQQQQQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 116 SSLLLEQARLLQQEQDRTReisdslgqlpQQQTDARRALTEVQRRLQ----AQPANPTTPYAQaALALLQTEAAARKAKV 191
Cdd:PRK10246 245 SLNWLTRLDELQQEASRRQ----------QALQQALAAEEKAQPQLAalslAQPARQLRPHWE-RIQEQSAALAHTRQQI 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 192 DELELAQLSANNRQelARMRAEVYKKrHEKIDVQLQALRNNLNAQ---RQREAELALEKTeQLAEQNGDlpksiSQQLqi 268
Cdd:PRK10246 314 EEVNTRLQSTMALR--ARIRHHAAKQ-SAELQAQQQSLNTWLAEHdrfRQWNNELAGWRA-QFSQQTSD-----REQL-- 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 269 nRELSAALNSQAQRMD------LISSQQRQAAAQTLQVRQalstiieqaqwlgsssalgETLRAQVATL-----PEMPKP 337
Cdd:PRK10246 383 -RQWQQQLTHAEQKLNalpaitLTLTADEVAAALAQHAEQ-------------------RPLRQRLVALhgqivPQQKRL 442
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 727177714 338 QQLDGDMAQLRVQRLQFENQLEKLSQREFKRD----DGSALTNQEQRIVDaqLRTQRELLNS 395
Cdd:PRK10246 443 AQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTqqlaDVKTICEQEARIKD--LEAQRAQLQA 502
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
25-408 |
2.12e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 2.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 25 ETQLKQELKQAESSKNAPNQAEttEALQSALNWLTERKESQTRSEQYQRViddfpkmtqeLRRQLVLESNKILPNGDdlP 104
Cdd:TIGR00618 374 QHTLTQHIHTLQQQKTTLTQKL--QSLCKELDILQREQATIDTRTSAFRD----------LQGQLAHAKKQQELQQR--Y 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQPANP------TTPYAQAALA 178
Cdd:TIGR00618 440 AELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPcplcgsCIHPNPARQD 519
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 179 LLQTEAAARKAKVDELELAQLS---ANNRQELA--RMRAEVYKKRHEKIDVQLQALRNNLNAQRQrEAELALEKTEQL-- 251
Cdd:TIGR00618 520 IDNPGPLTRRMQRGEQTYAQLEtseEDVYHQLTseRKQRASLKEQMQEIQQSFSILTQCDNRSKE-DIPNLQNITVRLqd 598
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 252 -AEQNGDLPKSISQQLQIN-RELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALS-TIIEQAQWLGSSSALGETLRAQV 328
Cdd:TIGR00618 599 lTEKLSEAEDMLACEQHALlRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTlTQERVREHALSIRVLPKELLASR 678
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 329 ATLP--EMPKPQQLDGDMAQLRVQRLQFENQLEKLSQREFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQILE 406
Cdd:TIGR00618 679 QLALqkMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA 758
|
..
gi 727177714 407 LT 408
Cdd:TIGR00618 759 RT 760
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
32-326 |
2.16e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.52 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 32 LKQAESSKNAPNQAETTEALQSALNWLTERKESQTRSEQYQRVIDDFPKMTQELRRQLVLESNKILPN-------GDDLP 104
Cdd:pfam09731 202 AKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQQELVSIFPDiipvlkeDNLLS 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQILQTssllleQARLLQQEQdrtreisdslgQLPQQQTDARRaltEVQRRLQAQPANpttpYAQAALALLQTEA 184
Cdd:pfam09731 282 NDDLNSLIAHA------HREIDQLSK-----------KLAELKKREEK---HIERALEKQKEE----LDKLAEELSARLE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 185 AARkakvdELELAQLsannRQELARMRAEVYKKRHEKIDVQL--------QALRNNLNAQRQREAELALEKTEQLAEQNG 256
Cdd:pfam09731 338 EVR-----AADEAQL----RLEFEREREEIRESYEEKLRTELerqaeaheEHLKDVLVEQEIELQREFLQDIKEKVEEER 408
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 727177714 257 DLpksisQQLQINrELSAALNSQAQRMDLISSQQRQA-AAQTLQVR-QALSTIIEQAQWLGSSSALGETLRA 326
Cdd:pfam09731 409 AG-----RLLKLN-ELLANLKGLEKATSSHSEVEDENrKAQQLWLAvEALRSTLEDGSADSRPRPLVRELKA 474
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
106-282 |
2.37e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 106 AELEQQILQTSSLLLE---QARLLQQEQDRTREISDSLGQLPQQQTD------ARRALTEVQRRLQAQPANPttpyaqAA 176
Cdd:COG4913 613 AALEAELAELEEELAEaeeRLEALEAELDALQERREALQRLAEYSWDeidvasAEREIAELEAELERLDASS------DD 686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 177 LALLQTEAAARKAKVDELELAQLSANNRQELArmraevyKKRHEKIDVQLQALRNNLN-AQRQREAELALEKTEQLAEQN 255
Cdd:COG4913 687 LAALEEQLEELEAELEELEEELDELKGEIGRL-------EKELEQAEEELDELQDRLEaAEDLARLELRALLEERFAAAL 759
|
170 180
....*....|....*....|....*...
gi 727177714 256 GD-LPKSISQQLQINRELSAALNSQAQR 282
Cdd:COG4913 760 GDaVERELRENLEERIDALRARLNRAEE 787
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
27-411 |
2.84e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 45.12 E-value: 2.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 27 QLKQELKQAE-SSKNAPNQAEttealqsalnwlterKESQTRSEQYQRVID---DFPKMTQELRRQLVLESNK----ILP 98
Cdd:pfam05557 13 QLQNEKKQMElEHKRARIELE---------------KKASALKRQLDRESDrnqELQKRIRLLEKREAEAEEAlreqAEL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 99 NGDDLPAAELEQQILQTSSLLLEQARLLQQE-QDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQPANpTTPYAQ--A 175
Cdd:pfam05557 78 NRLKKKYLEALNKKLNEKESQLADAREVISClKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAK-ASEAEQlrQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 176 ALALLQTEAAARKAKVDELEL--------AQLSANNRQELARM-RAEVYKKRHEKIDVQLQALRNN---LNAQ------- 236
Cdd:pfam05557 157 NLEKQQSSLAEAEQRIKELEFeiqsqeqdSEIVKNSKSELARIpELEKELERLREHNKHLNENIENkllLKEEvedlkrk 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 237 --RQREA-------ELALEKTEQ-------LAEQNG-------DLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQA 293
Cdd:pfam05557 237 leREEKYreeaatlELEKEKLEQelqswvkLAQDTGlnlrspeDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARREL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 294 AAqtlQVRQALSTIIEQAQWLGSSSALGETLRAQVATLpempkPQQLDGDMAQLRvqrlQFENQL--EKLSQREFKRDDG 371
Cdd:pfam05557 317 EQ---ELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLL-----TKERDGYRAILE----SYDKELtmSNYSPQLLERIEE 384
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 727177714 372 SALTNQEQRIVDAQLRTQRELLNSLLSG----CDTQILELTKLK 411
Cdd:pfam05557 385 AEDMTQKMQAHNEEMEAQLSVAEEELGGykqqAQTLERELQALR 428
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1-214 |
2.91e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 1 MRLFitLLLGCLLWQPALAAPVPTET------QLKQELKQAESSKNAPNQAETT-----EALQSALNWLTER-KESQTRS 68
Cdd:COG4942 1 MRKL--LLLALLLALAAAAQADAAAEaeaeleQLQQEIAELEKELAALKKEEKAllkqlAALERRIAALARRiRALEQEL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 69 EQYQRVIDDFPKMTQELRRQLVLESN------------------KILPNGDDLPAAELEQQILQT-SSLLLEQARLLQQE 129
Cdd:COG4942 79 AALEAELAELEKEIAELRAELEAQKEelaellralyrlgrqpplALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRAD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 130 QDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQTEAAARKAKVDELELAQLSANNRQELAR 209
Cdd:COG4942 159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
....*
gi 727177714 210 MRAEV 214
Cdd:COG4942 239 AAERT 243
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
9-329 |
3.92e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.05 E-value: 3.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 9 LGCLLWQPALAAPVPTETQLKQELKQAEssknapNQAETTEALQSALNwlterKESQTRSEQYQRVIDDFPKMTQE---L 85
Cdd:COG3883 2 LALALAAPTPAFADPQIQAKQKELSELQ------AELEAAQAELDALQ-----AELEELNEEYNELQAELEALQAEidkL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 86 RRQLvlesnkilpngddlpaAELEQQILQTSSLLLEQARLLQQEQDRTREI-----SDSLGQLPQQQtDARRALTEVQRR 160
Cdd:COG3883 71 QAEI----------------AEAEAEIEERREELGERARALYRSGGSVSYLdvllgSESFSDFLDRL-SALSKIADADAD 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 161 LQAQpanpttpyaqaaLALLQTEAAARKAKVDElELAQLSAnNRQELARMRAEVYKKRHEKidvqlQALRNNLNAQRQRE 240
Cdd:COG3883 134 LLEE------------LKADKAELEAKKAELEA-KLAELEA-LKAELEAAKAELEAQQAEQ-----EALLAQLSAEEAAA 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 241 AELALEKTEQLAEQNGDLPKSISQQLQINrelSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQWLGSSSAL 320
Cdd:COG3883 195 EAQLAELEAELAAAEAAAAAAAAAAAAAA---AAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGA 271
|
....*....
gi 727177714 321 GETLRAQVA 329
Cdd:COG3883 272 AGAGAAAAS 280
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
125-302 |
5.09e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 125 LLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQPANpttpYAQ---------AALALLQTEAAARKAKVDELE 195
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEE----YAElqeeleeleEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 196 LAQLSANNRQELARMRAEV--YKKRHEKIDVQLQALRNNLNAQRQREAELAlEKTEQLAEQNGDLPKSISQQLQ-INREL 272
Cdd:COG4717 123 KLLQLLPLYQELEALEAELaeLPERLEELEERLEELRELEEELEELEAELA-ELQEELEELLEQLSLATEEELQdLAEEL 201
|
170 180 190
....*....|....*....|....*....|
gi 727177714 273 SAALNSQAQRMDLISSQQRQAAAQTLQVRQ 302
Cdd:COG4717 202 EELQQRLAELEEELEEAQEELEELEEELEQ 231
|
|
| COG5281 |
COG5281 |
Phage-related minor tail protein [Mobilome: prophages, transposons]; |
50-490 |
5.77e-04 |
|
Phage-related minor tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444092 [Multi-domain] Cd Length: 603 Bit Score: 43.83 E-value: 5.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 50 ALQSALNWLTERKESQTRSEQYQRVIDDFPKMTQELRRQLVLESNKILPNGDDLPAAELEQQILQTSSLLLEQARLLQQE 129
Cdd:COG5281 11 AAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAAALAEDAAA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 130 QDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQTEAAARKAKVDELELAQLSANNRQELAR 209
Cdd:COG5281 91 AAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAALAAAAAAAAAAA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 210 MRAEVYKKRHEKIDVQLQALRNnLNAQRQREAELALEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQ 289
Cdd:COG5281 171 AAAAAAAALAAASAAAAAAAAK-AAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAASAAAQALAA 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 290 QRQAAAQTLQVRQALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLDGDMAQLRVQRLQFENQLEKLSQREFKRD 369
Cdd:COG5281 250 LAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAAAQALRAAAQ 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 370 DGSALTNQEQRIVDAQLRTQRELLNSLLsgcDTQILELTKLKVANTQLIEALNEIRDATHRYLfwvpdvnpINFSYPLNV 449
Cdd:COG5281 330 ALAALAQRALAAAALAAAAQEAALAAAA---AALQAALEAAAAAAAAELAAAGDWAAGAKAAL--------AEYADSATN 398
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 727177714 450 AHDLTRVLSLDTLSQLGGAFMMMVTSRETLIPIFGALLLVI 490
Cdd:COG5281 399 VAAQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASI 439
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
31-307 |
8.56e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.52 E-value: 8.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 31 ELKQAESSKNAPNQAETTEALQSALNWL-TERKESQTRSEQYQRVIDDFPKMTQELRRQLvlesnkilpngddlpaAELE 109
Cdd:TIGR02169 666 ILFSRSEPAELQRLRERLEGLKRELSSLqSELRRIENRLDELSQELSDASRKIGEIEKEI----------------EQLE 729
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 110 QQILQTSSLLLEQARLLQQ-EQDRT---REISDSLGQLPQQQTDA---RRALTEVQRRLQAQPanptTPYAQAALALLQT 182
Cdd:TIGR02169 730 QEEEKLKERLEELEEDLSSlEQEIEnvkSELKELEARIEELEEDLhklEEALNDLEARLSHSR----IPEIQAELSKLEE 805
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 183 EAAARKAKVDELElaqlSANNRQELARMRAEvyKKRHEKIDvQLQALRNNLNAQRQREAELALEKTE------------- 249
Cdd:TIGR02169 806 EVSRIEARLREIE----QKLNRLTLEKEYLE--KEIQELQE-QRIDLKEQIKSIEKEIENLNGKKEEleeeleeleaalr 878
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 727177714 250 QLAEQNGDLPKSISQ------QLQIN-RELSAALNSQAQRMdlissQQRQAAAQTLQvrQALSTI 307
Cdd:TIGR02169 879 DLESRLGDLKKERDEleaqlrELERKiEELEAQIEKKRKRL-----SELKAKLEALE--EELSEI 936
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
60-295 |
8.65e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 8.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 60 ERKESQTRSEQYQRVIDDFPKMTQELRRQLVL---ESNKILPNGDDLPA--AELEQQILQTSSLLLEQARLLQQEQDRTR 134
Cdd:TIGR02168 310 RLANLERQLEELEAQLEELESKLDELAEELAEleeKLEELKEELESLEAelEELEAELEELESRLEELEEQLETLRSKVA 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 135 EISDSLGQLPQQQTDARRALTEVQRRLQAQPANPTtpyaQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAEV 214
Cdd:TIGR02168 390 QLELQIASLNNEIERLEARLERLEDRRERLQQEIE----ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 215 YKKRHEKIDVQLQALRNNLNAQRQReaelaLEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAqrmDLISSQQRQAA 294
Cdd:TIGR02168 466 LREELEEAEQALDAAERELAQLQAR-----LDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS---ELISVDEGYEA 537
|
.
gi 727177714 295 A 295
Cdd:TIGR02168 538 A 538
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
121-310 |
1.11e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 121 EQARLLQ-QEQD-RTREISDSLGQLPQQQTDARRALTEVQRRLQAqpanpttpyAQAALALLQTEAAARKAKVDELelaq 198
Cdd:COG1579 5 DLRALLDlQELDsELDRLEHRLKELPAELAELEDELAALEARLEA---------AKTELEDLEKEIKRLELEIEEV---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 199 lsannRQELARMRAEVYKKRHEKidvQLQALRNNLNAQRQREAEL---ALEKTEQLAEQNGDLpKSISQQLQinrELSAA 275
Cdd:COG1579 72 -----EARIKKYEEQLGNVRNNK---EYEALQKEIESLKRRISDLedeILELMERIEELEEEL-AELEAELA---ELEAE 139
|
170 180 190
....*....|....*....|....*....|....*
gi 727177714 276 LNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQ 310
Cdd:COG1579 140 LEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
102-432 |
1.24e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.58 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 102 DLPAAELEQQILQTSSLLLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAQpanpttpyaQAALALLQ 181
Cdd:COG4372 2 DRLGEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQL---------EEELEQAR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 182 TEAAARKAKVDELELaQLSANNrQELARMRAEVykkrhEKIDVQLQALRNNLnAQRQREAELALEKTEQLAEQNGDLPKS 261
Cdd:COG4372 73 SELEQLEEELEELNE-QLQAAQ-AELAQAQEEL-----ESLQEEAEELQEEL-EELQKERQDLEQQRKQLEAQIAELQSE 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 262 ISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQtlQVRQALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLD 341
Cdd:COG4372 145 IAEREEELKELEEQLESLQEELAALEQELQALSEA--EAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 342 GDMAQLRVQRLQFENQLEKLSQREFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLSGCDTQILELTKLKVANTQLIEAL 421
Cdd:COG4372 223 AKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLL 302
|
330
....*....|.
gi 727177714 422 NEIRDATHRYL 432
Cdd:COG4372 303 NLAALSLIGAL 313
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
125-401 |
1.36e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 125 LLQQEQDRTREISDSLGQLPQQQTDARRALTEVQRRLQAqpANPTTPyaQAALaLLQTEAAAR----KAKVDELELAQLS 200
Cdd:COG3096 837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQL--LNKLLP--QANL-LADETLADRleelREELDAAQEAQAF 911
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 201 ----ANNRQELARMRA---------EVYKKRHEKIDVQLQALRNNLNAQ---RQREAELALEKTEQLAEQNGDLPKSISQ 264
Cdd:COG3096 912 iqqhGKALAQLEPLVAvlqsdpeqfEQLQADYLQAKEQQRRLKQQIFALsevVQRRPHFSYEDAVGLLGENSDLNEKLRA 991
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 265 QLQINRELSAALNSQAQrmdlissQQRQAAAQTLQVRQALStiieqaqwlGSSSALGETLRAQVATLPEMpkPQQLDGDM 344
Cdd:COG3096 992 RLEQAEEARREAREQLR-------QAQAQYSQYNQVLASLK---------SSRDAKQQTLQELEQELEEL--GVQADAEA 1053
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 727177714 345 ---AQLRVQRLQFE--------NQLEKlsQREFKRddgSALTNQEQRI--VDAQLRTQRELL-NSLLSGCD 401
Cdd:COG3096 1054 eerARIRRDELHEElsqnrsrrSQLEK--QLTRCE---AEMDSLQKRLrkAERDYKQEREQVvQAKAGWCA 1119
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
29-430 |
1.58e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 29 KQELKQAESSKNAPNQAETTEALQSALNWLTE----RKESQTRSEQYQRVIDDFPKMTQELRRQLVLESNKILPNGDDLP 104
Cdd:TIGR02168 331 KLDELAEELAELEEKLEELKEELESLEAELEEleaeLEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 105 AAELEQQILQTSSLLLEQARLLQQEQDRTREISDS---LGQLPQQQTDARRALTEVQRRLQAqpanpttpyAQAALALLQ 181
Cdd:TIGR02168 411 RLEDRRERLQQEIEELLKKLEEAELKELQAELEELeeeLEELQEELERLEEALEELREELEE---------AEQALDAAE 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 182 TEAAARKAKVDELELAQlsaNNRQELARMRAEVYKKRH----------EKIDVQ--------------LQAL-RNNLNAQ 236
Cdd:TIGR02168 482 RELAQLQARLDSLERLQ---ENLEGFSEGVKALLKNQSglsgilgvlsELISVDegyeaaieaalggrLQAVvVENLNAA 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 237 RQ---------------------REAELALEKTEQLAEQNGDLpKSISQQLQINRELSAALNSQAQRMdLISSQQRQAAA 295
Cdd:TIGR02168 559 KKaiaflkqnelgrvtflpldsiKGTEIQGNDREILKNIEGFL-GVAKDLVKFDPKLRKALSYLLGGV-LVVDDLDNALE 636
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 296 QTLQVRQALSTIIEQAQWLG------------SSSALG-----ETLRAQVATLPEmpKPQQLDGDMAQLRVQRLQFENQL 358
Cdd:TIGR02168 637 LAKKLRPGYRIVTLDGDLVRpggvitggsaktNSSILErrreiEELEEKIEELEE--KIAELEKALAELRKELEELEEEL 714
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 727177714 359 EKLSQREFKRDDGSALTNQEQRIVDAQLRTQRELLNSLLsgcdtqiLELTKLKVANTQLIEALNEIRDATHR 430
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS-------KELTELEAEIEELEERLEEAEEELAE 779
|
|
| PTZ00491 |
PTZ00491 |
major vault protein; Provisional |
122-253 |
2.07e-03 |
|
major vault protein; Provisional
Pssm-ID: 240439 [Multi-domain] Cd Length: 850 Bit Score: 42.31 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 122 QARLLQQEqdrtreisdSLGQLPQQQT-DarRALTEVQRR--LQAQPANPTTPYAQAALALLQTEAAARKAKVdELELAQ 198
Cdd:PTZ00491 671 QAELLEQE---------ARGRLERQKMhD--KAKAEEQRTklLELQAESAAVESSGQSRAEALAEAEARLIEA-EAEVEQ 738
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 727177714 199 lsannrqelARMRAEVYKKRHEKIDVQLQALRNNLNAQRQREAELALEKTEQLAE 253
Cdd:PTZ00491 739 ---------AELRAKALRIEAEAELEKLRKRQELELEYEQAQNELEIAKAKELAD 784
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
111-430 |
2.46e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 111 QILQTSSLlleQARLLQQEQDRTREISDSL-------GQLPQQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQTE 183
Cdd:pfam10174 165 EMLQSKGL---PKKSGEEDWERTRRIAEAEmqlghleVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTK 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 184 AAARKAKVDELEL--------AQLSANNRQELARmRAEVYKKRHEKIDVQLQALRNNLNaqrQREAEL-ALE-KTEQLAE 253
Cdd:pfam10174 242 ISSLERNIRDLEDevqmlktnGLLHTEDREEEIK-QMEVYKSHSKFMKNKIDQLKQELS---KKESELlALQtKLETLTN 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 254 QNGDlpksISQQLQINRElsaALNSQAQRMDLIssqQRQAAAQTLQVRQALSTIIEQAQWLGSSSALGETLRAQVATLPE 333
Cdd:pfam10174 318 QNSD----CKQHIEVLKE---SLTAKEQRAAIL---QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKD 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 334 MpkpqqLDGDMAQLRVQRLQFENQLEKLsqrefkRDDGSALTNQEQRIVDAQLRTqrellnsllSGCDTQILELTKLKVA 413
Cdd:pfam10174 388 M-----LDVKERKINVLQKKIENLQEQL------RDKDKQLAGLKERVKSLQTDS---------SNTDTALTTLEEALSE 447
|
330
....*....|....*..
gi 727177714 414 NTQLIEALNEIRDATHR 430
Cdd:pfam10174 448 KERIIERLKEQREREDR 464
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
60-296 |
2.53e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 41.44 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 60 ERKESQTRSEQYQRVIDDFPKMTQELRRQLVLESNkilpngddlpaaELEQQILQTSSLLLEQARLLQQEQDRTREISDs 139
Cdd:pfam13868 117 EAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEER------------EEDERILEYLKEKAEREEEREAEREEIEEEKE- 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 140 lgqlpQQQTDARRALTEVQRRLQAQpanpttpyaQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAE--VYKK 217
Cdd:pfam13868 184 -----REIARLRAQQEKAQDEKAER---------DELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAREEqiELKE 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 218 RHEKIDVQL-QALRNNLNAQRQREAELALEKTEQLAEQNGDLPKSISQQLQINRELSAAlnsQAQRMDLISSQQRQAAAQ 296
Cdd:pfam13868 250 RRLAEEAEReEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAA---EREEELEEGERLREEEAE 326
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
27-416 |
2.56e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 27 QLKQELKQAESSknapnqaetTEALQSALNWLTERkesQTRSEQYQRVIDdfpkmtqelrrqlvlESnkilpngddLPAA 106
Cdd:pfam10174 293 QLKQELSKKESE---------LLALQTKLETLTNQ---NSDCKQHIEVLK---------------ES---------LTAK 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 107 ELEQQILQT--SSL---LLEQARLLQQEQDRTREISDSLGQLPQQQTDARRALtEVQRR----LQAQPANpttpyaqaal 177
Cdd:pfam10174 337 EQRAAILQTevDALrlrLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDML-DVKERkinvLQKKIEN---------- 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 178 alLQTEAAARKAKVDEL-----ELAQLSANNRQELARMRAEVYKKrhEKIdvqLQALRNnlnaQRQREAELALEKTEQLA 252
Cdd:pfam10174 406 --LQEQLRDKDKQLAGLkervkSLQTDSSNTDTALTTLEEALSEK--ERI---IERLKE----QREREDRERLEELESLK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 253 EQNGDLPKSISQQLQINRELSAALN-------SQAQRMDLISSQQRQAAAQTLQVRQ---ALSTIIEQAQWLGSSSALGE 322
Cdd:pfam10174 475 KENKDLKEKVSALQPELTEKESSLIdlkehasSLASSGLKKDSKLKSLEIAVEQKKEecsKLENQLKKAHNAEEAVRTNP 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 323 TLRAQVATLPEMPKPQQLDGDMAQLRVQRL-----QFENQ----------LEKLSQREFK----------------RDDG 371
Cdd:pfam10174 555 EINDRIRLLEQEVARYKEESGKAQAEVERLlgilrEVENEkndkdkkiaeLESLTLRQMKeqnkkvanikhgqqemKKKG 634
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 727177714 372 SALTNQEQRIVDAQLRTQRELLNSLLSGCDT---QILELTKLKVANTQ 416
Cdd:pfam10174 635 AQLLEEARRREDNLADNSQQLQLEELMGALEktrQELDATKARLSSTQ 682
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
61-395 |
2.71e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.87 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 61 RKESQTRSEQYqRVIDDFPKMTQELRRQLVlesnkilpngddlpAAELEQQILQTsslLLEQARLLQQE--QDRTREISD 138
Cdd:PRK04863 840 RQLNRRRVELE-RALADHESQEQQQRSQLE--------------QAKEGLSALNR---LLPRLNLLADEtlADRVEEIRE 901
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 139 SLGQLPQQQTDARRAltevqrrlqaqpanpttpyaQAALALLQTEAAARKAkvDELELAQLsannrqelarmraevyKKR 218
Cdd:PRK04863 902 QLDEAEEAKRFVQQH--------------------GNALAQLEPIVSVLQS--DPEQFEQL----------------KQD 943
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 219 HEKIDVQLQALRNNLNAQ---RQREAELALEKTEQLAEQNGDLPKSISQQLQinrelsaalnsQAQRM-DLISSQQRQAA 294
Cdd:PRK04863 944 YQQAQQTQRDAKQQAFALtevVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLE-----------QAEQErTRAREQLRQAQ 1012
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 295 AQTLQVRQALSTIIeqaqwlGSSSALGETLRAQVATLPEMPKPqqLDGDM-AQLRVQRLQFENQL----EKLSQREFKRD 369
Cdd:PRK04863 1013 AQLAQYNQVLASLK------SSYDAKRQMLQELKQELQDLGVP--ADSGAeERARARRDELHARLsanrSRRNQLEKQLT 1084
|
330 340
....*....|....*....|....*....
gi 727177714 370 -DGSALTNQEQRIVDAQ--LRTQRELLNS 395
Cdd:PRK04863 1085 fCEAEMDNLTKKLRKLErdYHEMREQVVN 1113
|
|
| tolA |
PRK09510 |
cell envelope integrity inner membrane protein TolA; Provisional |
141-244 |
3.29e-03 |
|
cell envelope integrity inner membrane protein TolA; Provisional
Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 41.33 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 141 GQLPQQQTDARRAltEVQRRLQAQPANPTtpyaqaalalLQTEAAARKAKVDELELAQLSANNRQ----ELARMRAEVYK 216
Cdd:PRK09510 65 NRQQQQQKSAKRA--EEQRKKKEQQQAEE----------LQQKQAAEQERLKQLEKERLAAQEQKkqaeEAAKQAALKQK 132
|
90 100
....*....|....*....|....*...
gi 727177714 217 KRHEKIDVQLQALRNNLNAQRQREAELA 244
Cdd:PRK09510 133 QAEEAAAKAAAAAKAKAEAEAKRAAAAA 160
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
24-411 |
5.29e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.19 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 24 TETQLKQELKQAESSKNAPNQAETTEalqsaLNWLTERKESQTRSEQYQRV--IDDFPKMTQElRRQLVLESNKIL--PN 99
Cdd:TIGR00606 277 RKKQMEKDNSELELKMEKVFQGTDEQ-----LNDLYHNHQRTVREKERELVdcQRELEKLNKE-RRLLNQEKTELLveQG 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 100 GDDLPAAELEQQILQTSSLLLEQARLLQ-----------------------QEQDRTREISDSLGQLPQQQTDARRALTE 156
Cdd:TIGR00606 351 RLQLQADRHQEHIRARDSLIQSLATRLEldgfergpfserqiknfhtlvieRQEDEAKTAAQLCADLQSKERLKQEQADE 430
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 157 VQRRLQAQPAnpttpyaqaalaLLQTEAAARKAKVDELElaqlsaNNRQELarMRAEVYKKRHEKIDVQL-QALRNNLNA 235
Cdd:TIGR00606 431 IRDEKKGLGR------------TIELKKEILEKKQEELK------FVIKEL--QQLEGSSDRILELDQELrKAERELSKA 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 236 QRQREAELALEKTEQLAEQNGDLPKSISQQLQINRELSAALNSQAQrMDLISSQQRQAAAQtlqvrqalstiIEQAQWLG 315
Cdd:TIGR00606 491 EKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQ-MEMLTKDKMDKDEQ-----------IRKIKSRH 558
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 316 SSSALGEtlraqvatLPEMPKPQQLDGDMAQLRVQRLQFENQLEKLSQREFKRDDGSALTNQEQRIVDAQLRTQREllnS 395
Cdd:TIGR00606 559 SDELTSL--------LGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYED---K 627
|
410
....*....|....*...
gi 727177714 396 LLSGCDTQILE--LTKLK 411
Cdd:TIGR00606 628 LFDVCGSQDEEsdLERLK 645
|
|
| tolA_full |
TIGR02794 |
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ... |
13-332 |
5.33e-03 |
|
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 40.21 E-value: 5.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 13 LWQPALAAPVPTETQLKQeLKQAESSKNAPNQAETTEALQSALNWLTERKESQTRseqyqrviddfpkmTQELRRQlvle 92
Cdd:TIGR02794 37 IIQAVLVDPGAVAQQANR-IQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQAR--------------QKELEQR---- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 93 snkilpngddLPAAELEQQIlqtsslllEQARLLQQEQDRTREisdslGQLPQQQTDARRAltevqrrlqaqpanpttpy 172
Cdd:TIGR02794 98 ----------AAAEKAAKQA--------EQAAKQAEEKQKQAE-----EAKAKQAAEAKAK------------------- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 173 AQAALALLQTEAAARKAKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQ---ALRNNLNAQRQREAElALEKTE 249
Cdd:TIGR02794 136 AEAEAERKAKEEAAKQAEEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKaeeAKAKAEAAKAKAAAE-AAAKAE 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 250 QLAEQNGDLPKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQ---TLQVRQALstiieQAQWLGSSSALGETLRA 326
Cdd:TIGR02794 215 AEAAAAAAAEAERKADEAELGDIFGLASGSNAEKQGGARGAAAGSEVdkyAAIIQQAI-----QQNLYDDPSFRGKTCRL 289
|
....*.
gi 727177714 327 QVATLP 332
Cdd:TIGR02794 290 RIRLAP 295
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
17-212 |
5.57e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.09 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 17 ALAAPVPTET---QLKQELKQAESSKNapnQAETTEALQSALNWLTERKESQTRSEqyqrviddfpkmtqELRRQLVLES 93
Cdd:COG3096 483 KIAGEVERSQawqTARELLRRYRSQQA---LAQRLQQLRAQLAELEQRLRQQQNAE--------------RLLEEFCQRI 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 94 NKILPNGDDLPA--AELEQQILQTSSLL---LEQARLLQQEQDRTREISDSLGQLPQQQTDARRALTevqrRLQAQPANP 168
Cdd:COG3096 546 GQQLDAAEELEEllAELEAQLEELEEQAaeaVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALE----RLREQSGEA 621
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 727177714 169 TTPyAQAALALLQT-------------EAAARKAKVdELELAQLSANNRQELARMRA 212
Cdd:COG3096 622 LAD-SQEVTAAMQQllerereatverdELAARKQAL-ESQIERLSQPGGAEDPRLLA 676
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
179-395 |
6.18e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 6.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 179 LLQTEAAARKAKVDELELAQLSANNRQELARMRaevYKKRHEKIDVQLQALRNNLnAQRQREAELALEKTEQLAEQNGDL 258
Cdd:pfam07888 31 LLQNRLEECLQERAELLQAQEAANRQREKEKER---YKRDREQWERQRRELESRV-AELKEELRQSREKHEELEEKYKEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 259 PKSISQQLQINRELSAALNSQAQRMDLISSQQRQAAAQTLQVRQALSTIIEQAQWLGSS--------SALGETLRAQVAT 330
Cdd:pfam07888 107 SASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQrkeeeaerKQLQAKLQQTEEE 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 727177714 331 LPEMPKP-QQLDGDMAQLRVQRLQFENQLEKLSQRefkrddgsaLTNQEQRIVD-----AQLRTQRELLNS 395
Cdd:pfam07888 187 LRSLSKEfQELRNSLAQRDTQVLQLQDTITTLTQK---------LTTAHRKEAEneallEELRSLQERLNA 248
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
136-427 |
7.01e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.41 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 136 ISDSLGQLPQQQTDARRALTEVqrRLQAQPANPTTPYAQAALALLQTEAAARKAKVDELELAQLSA-----NNRQELARM 210
Cdd:PRK02224 312 VEARREELEDRDEELRDRLEEC--RVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreaveDRREEIEEL 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 211 RAEV--YKKRHEKIDVQL-------QALRNNLNAQRQREAEL---------ALEKTEQLAEQnGDLPKSiSQQLQINREL 272
Cdd:PRK02224 390 EEEIeeLRERFGDAPVDLgnaedflEELREERDELREREAELeatlrtareRVEEAEALLEA-GKCPEC-GQPVEGSPHV 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 273 SAALNSQAQRMDLiSSQQRQAAAQtlqvRQALSTIIEQAQWLGSSSALGETLRAQVATLPEMPKPQQLDGDMAQLRVQRL 352
Cdd:PRK02224 468 ETIEEDRERVEEL-EAELEDLEEE----VEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEEL 542
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 727177714 353 QfENQLEKLSQREFKRDDGSALTN--QEQRIVDAQLRTQRELLNSLLSGCDTqILELTKLKVANTQLIEALNEIRDA 427
Cdd:PRK02224 543 R-ERAAELEAEAEEKREAAAEAEEeaEEAREEVAELNSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREA 617
|
|
| PRK11637 |
PRK11637 |
AmiB activator; Provisional |
127-312 |
7.59e-03 |
|
AmiB activator; Provisional
Pssm-ID: 236942 [Multi-domain] Cd Length: 428 Bit Score: 40.06 E-value: 7.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 127 QQEQDRtreiSDSLGQLPQQQT---DARRALTEVQRRLQAqpANPTTPYAQAALALLQTeaaaRKAKVDELELAQLSANN 203
Cdd:PRK11637 65 QQQQQR----ASLLAQLKKQEEaisQASRKLRETQNTLNQ--LNKQIDELNASIAKLEQ----QQAAQERLLAAQLDAAF 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 204 RQ------ELARMRAEvyKKRHEKIdvqlQALRNNLNAQRQREAElALEKT-EQLAEQNGDLPKSISQQlqinRELSAAL 276
Cdd:PRK11637 135 RQgehtglQLILSGEE--SQRGERI----LAYFGYLNQARQETIA-ELKQTrEELAAQKAELEEKQSQQ----KTLLYEQ 203
|
170 180 190
....*....|....*....|....*....|....*.
gi 727177714 277 NSQAQRMDlissQQRQAAAQTLqvrQALSTIIEQAQ 312
Cdd:PRK11637 204 QAQQQKLE----QARNERKKTL---TGLESSLQKDQ 232
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
26-399 |
7.89e-03 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 40.55 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 26 TQLKQELKQAESSKNAPNQAETTEALQSA----------LNWLTERKESQTRS-----EQYQRVIDDFPKMTQ---ELRR 87
Cdd:PRK10246 253 DELQQEASRRQQALQQALAAEEKAQPQLAalslaqparqLRPHWERIQEQSAAlahtrQQIEEVNTRLQSTMAlraRIRH 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 88 QLVLESNKILPNGDDLPA--AELEQQILQTSSLLLEQARLLQQEQDRtreisdslgqlpQQQTDARRALTEVQRRLQAQP 165
Cdd:PRK10246 333 HAAKQSAELQAQQQSLNTwlAEHDRFRQWNNELAGWRAQFSQQTSDR------------EQLRQWQQQLTHAEQKLNALP 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 166 ANPTTPYAQAALALLQTEAAARKAkvdelelaqlsannRQELARMRAEVYKKRHEKidVQLQALRNNLNAQRQREAELAL 245
Cdd:PRK10246 401 AITLTLTADEVAAALAQHAEQRPL--------------RQRLVALHGQIVPQQKRL--AQLQVAIQNVTQEQTQRNAALN 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 246 EKTEQLAEQNGDLP--KSISQQLQINRELS---AALNS----------------QAQRMDLISSQQRQAAAQT------- 297
Cdd:PRK10246 465 EMRQRYKEKTQQLAdvKTICEQEARIKDLEaqrAQLQAgqpcplcgstshpaveAYQALEPGVNQSRLDALEKevkklge 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 298 --LQVRQALSTIIEQAQ--------WLGSSSALGETLRAQVATLPEMPKPQQldgDMAQLRVQRLQFENQLEKLSQREFK 367
Cdd:PRK10246 545 egAALRGQLDALTKQLQrdeseaqsLRQEEQALTQQWQAVCASLNITLQPQD---DIQPWLDAQEEHERQLRLLSQRHEL 621
|
410 420 430
....*....|....*....|....*....|..
gi 727177714 368 RDDGSALTNQEQRIvDAQLRTQRELLNSLLSG 399
Cdd:PRK10246 622 QGQIAAHNQQIIQY-QQQIEQRQQQLLTALAG 652
|
|
| PRK06975 |
PRK06975 |
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed |
7-212 |
8.55e-03 |
|
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
Pssm-ID: 235899 [Multi-domain] Cd Length: 656 Bit Score: 40.09 E-value: 8.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 7 LLLGCLLW-----QPALAAPVPTETQLKQELKQ--------AESSKNAPNQAETTEALQ------SALNWLT-------- 59
Cdd:PRK06975 258 IVRAFLTWadaaaQPATAAPAPSRMTDTNDSKSvtsqpaaaAAAPAPPPNPPATPPEPParrgrgSAALWFVvvvlacaa 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 60 -----------ERKESQTRSEQYQRviddfPKMTQELRRQL--VLESNKILpngdDLPAAELEQQILQTSSlllEQARLL 126
Cdd:PRK06975 338 avggyalnrkvDRLDQELVQRQQAN-----DAQTAELRVKTeqAQASVHQL----DSQFAQLDGKLADAQS---AQQALE 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 127 QQEQDRTREISDslgqlpQQQTDARRALTEVQRRLQaqpanpTTPYAQAALALLQTeAAARKAKVDELELAQLSANNRQE 206
Cdd:PRK06975 406 QQYQDLSRNRDD------WMIAEVEQMLSSASQQLQ------LTGNVQLALIALQN-ADARLATSDSPQAVAVRKAIAQD 472
|
....*.
gi 727177714 207 LARMRA 212
Cdd:PRK06975 473 IERLKA 478
|
|
| PRK12757 |
PRK12757 |
cell division protein FtsN; Provisional |
110-249 |
8.57e-03 |
|
cell division protein FtsN; Provisional
Pssm-ID: 237191 [Multi-domain] Cd Length: 256 Bit Score: 39.26 E-value: 8.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 110 QQILQTSSLLLEQARLLQQEQDRTREISDSLGQLP-QQQTDARRALTEVQRRLQAQPANPTTPYAQAALALLQTEAAARK 188
Cdd:PRK12757 72 GEVNSPTQLTDEQRQLLEQMQADMRQQPTQLSEVPyNEQTPQVPRSTVQIQQQAQQQQPPATTAQPQPVTPPRQTTAPVQ 151
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 727177714 189 AKVDELELAQLSANNRQELARMRAEVYKKRHEKIDVQLQALRNNLNAQRQReAELALEKTE 249
Cdd:PRK12757 152 PQTPAPVRTQPAAPVTQAVEAPKVEAEKEKEQRWMVQCGSFKGTEQAESVR-AQLAFAGIE 211
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
205-398 |
9.09e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.00 E-value: 9.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 205 QELARMRAEVYKKRHEKIDVQLQALRNNLnaqrqREAELALEkteQLAEQNGDLpkSISQQLQINRELSAALNSQAQRmd 284
Cdd:COG3206 163 EQNLELRREEARKALEFLEEQLPELRKEL-----EEAEAALE---EFRQKNGLV--DLSEEAKLLLQQLSELESQLAE-- 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177714 285 lISSQQRQAAAQTLQVRQALSTIIEQAQWLGSSSALGE------TLRAQVATL-----PEMPKPQQLDGDMAQLRVQRLQ 353
Cdd:COG3206 231 -ARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQlraqlaELEAELAELsarytPNHPDVIALRAQIAALRAQLQQ 309
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 727177714 354 --------FENQLEKLSQREFK--------RDDGSALTNQEQRIVDAQ--LRTQRELLNSLLS 398
Cdd:COG3206 310 eaqrilasLEAELEALQAREASlqaqlaqlEARLAELPELEAELRRLEreVEVARELYESLLQ 372
|
|
| |
