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Conserved domains on  [gi|727177637|ref|WP_033641576|]
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MULTISPECIES: glutamate/aspartate:proton symporter GltP [Serratia]

Protein Classification

proton/glutamate symporter( domain architecture ID 10013774)

proton/glutamate symporter, similar to E.coli GltP, imports glutamate coupled with the import of H+; belongs to the dicarboxylate/amino acid:cation symporter family

Gene Ontology:  GO:0005280|GO:0022857

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


:

Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 773.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   1 MKSVKISLAWQILIALVLGIIVGAVLHNQTESREWLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  81 GLKTIIYFEVITTIAIVVGLTLANVFQPGHGIDMSTLTTVDISQYEKTTEQVQSGSHSLVATILSLIPSNVFSSMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 161 LPIIFFSVLFGLGLSSLPKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 241 IAFFALVVLGAVARLCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 321 SIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 727177637 401 NALAVLVIAKWEHQFDRKKALAYETEFLAQKVKPANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 773.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   1 MKSVKISLAWQILIALVLGIIVGAVLHNQTESREWLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  81 GLKTIIYFEVITTIAIVVGLTLANVFQPGHGIDMSTLTTVDISQYEKTTEQVQSGSHSLVATILSLIPSNVFSSMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 161 LPIIFFSVLFGLGLSSLPKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 241 IAFFALVVLGAVARLCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 321 SIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 727177637 401 NALAVLVIAKWEHQFDRKKALAYETEFLAQKVKPANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
5-424 3.24e-167

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 475.76  E-value: 3.24e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   5 KISLAWQILIALVLGIIVGAVLHNqtesrewLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKT 84
Cdd:COG1301    2 KLSLTLQILIALVLGILLGLLLPE-------LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKT 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  85 IIYFEVITTIAIVVGLTLANVFQPGHGIDMSTLTTVDISQyektteqvqSGSHSLVATILSLIPSNVFSSMAKGDMLPII 164
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQII 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 165 FFSVLFGLGLSSLpKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAFF 244
Cdd:COG1301  146 FFAILFGIALAAL-GEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLH 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 245 ALVVLGAVAR-LCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKM-EAYGAPKSITSFVVPTGYSFNLDGSTLYQSI 322
Cdd:COG1301  225 LFVVLPLILRlLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQAV 304
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 323 AAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
Cdd:COG1301  305 AALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDA 384
                        410       420
                 ....*....|....*....|..
gi 727177637 403 LAVLVIAKWEHQFDRKKALAYE 424
Cdd:COG1301  385 VATVVVAKWEGELDREKLNAAL 406
SDF pfam00375
Sodium:dicarboxylate symporter family;
8-411 1.13e-121

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 359.14  E-value: 1.13e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637    8 LAWQILIALVLGIIVGAVLHNqtesrewlVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKTIIY 87
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPE--------LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   88 FEVITTIAIVVGLTLANVFQPGHGIdmstlttVDISQYEKTTEQVQSGShsLVATILSLIPSNVFSSMAKGDMLPIIFFS 167
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGL-------ALIAASLKEAKAAEAPS--LLDFILNIIPSNIFEALAEGNVLAVIVFA 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  168 VLFGLGLSSLPKEtKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAFFALV 247
Cdd:pfam00375 144 ILFGIALAALGEK-GEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLI 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  248 VLGAVAR-LCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAI 325
Cdd:pfam00375 223 VYPLLIKfLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  326 FIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405
Cdd:pfam00375 303 FIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAA 382

                  ....*.
gi 727177637  406 LVIAKW 411
Cdd:pfam00375 383 VIVAKL 388
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
1-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 773.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   1 MKSVKISLAWQILIALVLGIIVGAVLHNQTESREWLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRI 80
Cdd:PRK11283   1 MKNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  81 GLKTIIYFEVITTIAIVVGLTLANVFQPGHGIDMSTLTTVDISQYEKTTEQVQSGSHSLVATILSLIPSNVFSSMAKGDM 160
Cdd:PRK11283  81 GAKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 161 LPIIFFSVLFGLGLSSLPKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFA 240
Cdd:PRK11283 161 LPIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 241 IAFFALVVLGAVARLCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
Cdd:PRK11283 241 ILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 321 SIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
Cdd:PRK11283 321 SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG 400
                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 727177637 401 NALAVLVIAKWEHQFDRKKALAYETEFLAQKVKPANQ 437
Cdd:PRK11283 401 NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ 437
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
5-424 3.24e-167

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 475.76  E-value: 3.24e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   5 KISLAWQILIALVLGIIVGAVLHNqtesrewLVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKT 84
Cdd:COG1301    2 KLSLTLQILIALVLGILLGLLLPE-------LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKT 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  85 IIYFEVITTIAIVVGLTLANVFQPGHGIDMSTLTTVDISQyektteqvqSGSHSLVATILSLIPSNVFSSMAKGDMLPII 164
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQII 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 165 FFSVLFGLGLSSLpKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAFF 244
Cdd:COG1301  146 FFAILFGIALAAL-GEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLH 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 245 ALVVLGAVAR-LCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKM-EAYGAPKSITSFVVPTGYSFNLDGSTLYQSI 322
Cdd:COG1301  225 LFVVLPLILRlLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQAV 304
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 323 AAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
Cdd:COG1301  305 AALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDA 384
                        410       420
                 ....*....|....*....|..
gi 727177637 403 LAVLVIAKWEHQFDRKKALAYE 424
Cdd:COG1301  385 VATVVVAKWEGELDREKLNAAL 406
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
1-420 2.71e-148

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 428.55  E-value: 2.71e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   1 MKSVKISLAWQILIALVLGIIVGAVLHNQTESrewlvsniLSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRI 80
Cdd:PRK01663   2 KKPLYKSLYFQVLVAIIIGILLGHFYPELGAQ--------MKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMGDMKKVGRV 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  81 GLKTIIYFEVITTIAIVVGLTLANVFQPGHG--IDMSTLTTVDISQYEKtteqvQSGSHSLVATILSLIPSNVFSSMAKG 158
Cdd:PRK01663  74 GGKALLYFEIVSTIALIIGLIVVNVVQPGAGmnIDPATLDAKAVAQYAA-----QAHEQGTVDFLMDIIPTTVVGAFASG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 159 DMLPIIFFSVLFGLGLSSLpKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVY 238
Cdd:PRK01663 149 DILQVLLFAVLFGFALARL-GEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIGKYGVGSLVQLGQLIGCFY 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 239 FAIAFFALVVLGAVARLCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTL 318
Cdd:PRK01663 228 ITCILFVFVVLGAIARLTGFSIFKFIRYIKEELLIVLGTSSSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSI 307
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 319 YQSIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALN 397
Cdd:PRK01663 308 YLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTN 387
                        410       420
                 ....*....|....*....|...
gi 727177637 398 VVGNALAVLVIAKWEHQFDRKKA 420
Cdd:PRK01663 388 LIGNGVATVVVAKWEKELDREKL 410
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
7-422 4.17e-126

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 371.69  E-value: 4.17e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   7 SLAWQILIALVLGIIVGAVLHNQTESrewlvsniLSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKTII 86
Cdd:PRK13027   7 SLFGQVVIALVLGVALGAFFPHFAES--------LKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAGDLKKVGRVGLKAVI 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  87 YFEVITTIAIVVGLTLANVFQPGHG--IDMSTLTTVDISQYEKTTEQVqsgsHSLVATILSLIPSNVFSSMAKGDMLPII 164
Cdd:PRK13027  79 YFEVMTTIALVIGLVLAYLTGPGVGmnIDLRSLDAASLAGYAKNAQSL----KGTAGFLLKLIPTTAVDAFAKGDILQVL 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 165 FFSVLFGLGLSsLPKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAFF 244
Cdd:PRK13027 155 LFSVLFGSALS-LLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAFTTGKYGVGSLKQLGMLVAVFYLTCFVF 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 245 ALVVLGAVARLCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAA 324
Cdd:PRK13027 234 VVVVLGAVMRLAGFSVFKLIRYLREELLIVLGTASSDAVLPQVMRKLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAA 313
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 325 IFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALNVVGNAL 403
Cdd:PRK13027 314 VFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCV 393
                        410
                 ....*....|....*....
gi 727177637 404 AVLVIAKWEHQFDRKKALA 422
Cdd:PRK13027 394 ATVVVAVWENDIDRARAQA 412
SDF pfam00375
Sodium:dicarboxylate symporter family;
8-411 1.13e-121

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 359.14  E-value: 1.13e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637    8 LAWQILIALVLGIIVGAVLHNqtesrewlVSNILSPAGDIFIRLIKMIVVPIVISTLIVGIAGVGDAKKLGRIGLKTIIY 87
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPE--------LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   88 FEVITTIAIVVGLTLANVFQPGHGIdmstlttVDISQYEKTTEQVQSGShsLVATILSLIPSNVFSSMAKGDMLPIIFFS 167
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGL-------ALIAASLKEAKAAEAPS--LLDFILNIIPSNIFEALAEGNVLAVIVFA 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  168 VLFGLGLSSLPKEtKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAFFALV 247
Cdd:pfam00375 144 ILFGIALAALGEK-GEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLI 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  248 VLGAVAR-LCNLRIWTLIRILKDELILAYSTASSETVLPRIIEKME-AYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAI 325
Cdd:pfam00375 223 VYPLLIKfLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAI 302
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  326 FIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405
Cdd:pfam00375 303 FIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAA 382

                  ....*.
gi 727177637  406 LVIAKW 411
Cdd:pfam00375 383 VIVAKL 388
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
1-419 1.75e-38

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 144.58  E-value: 1.75e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   1 MKSVKISLAWQILIALVLGIIVGAVLHN--------QTESREWLvsNILspaGDIFIRLIKMIVVPIVISTLIVGIAGVG 72
Cdd:COG1823   23 MQKKHVSFSKRVFTGLGLGILFGLILQLiygagspvIKQSIDWF--NIV---GNGYVRLLQMIVMPLVFVSILSAITKLK 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  73 DAKKLGRIGLKTIIYFEVITTIAIVVGLTLANVFqpghGIDMSTLT-----TVDISQYEKTTEQVQSGShsLVATILSLI 147
Cdd:COG1823   98 NASSLGKISGLIIGILLGTTAIAALVGILVALLF----GLTAEGLTqgaaeTARGEALEERLGEVEDLS--LPQQILSFI 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 148 PSNVFSSMAKGDMLPII---FFSVLFG---LGLSSLPKETKEPLLKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVAN 221
Cdd:COG1823  172 PTNPFADLTGARPTSTIavvIFAAFLGiaaLGLRRKKPEQAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMTKVVAT 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 222 FGFASLLPLAKLVVLVYFAIAFFALV--VLGAVARLCNLR----IWTLirilkdeLILAYSTASSETVLPRIIE-KMEAY 294
Cdd:COG1823  252 SDFADILNLGKFVVASYVALIIMFIVhlLLLALAGLNPLTyfkkVWPV-------LTFAFTSRSSAGTIPLNIEtQTKRL 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 295 GAPKSITSFVVPTGYSFNLDG-STLYQSIAAIFIAQLYGIE-LSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSV 372
Cdd:COG1823  325 GVPEGIANFAASFGATIGQNGcAGIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAM 404
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 727177637 373 GIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHQFDRKK 419
Cdd:COG1823  405 GLPVALAGLLISIEPLIDMGRTALNVSGSMTAGTVTSRLLGQLDKDI 451
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
5-397 1.01e-22

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 99.48  E-value: 1.01e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   5 KISLAWQILIALVLGIIVGAVLHNQTESREWLvsnilspaGDIFIRLIKMiVVPIVISTLIvgIAGVGDAKKLGRIGLKT 84
Cdd:COG3633   12 RGSLVKQILIGLVLGILLALLSPEAAKSVGLL--------GTLFVGALKA-VAPILVFVLV--MSAIANHKQGQKTNMKP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  85 IIYFEVITT-IAIVVGLTLANVFQpghgidmSTLTTVDisqyEKTTEQVQSGSHSLVATILSLIPSNVFSSMAKGDMLPI 163
Cdd:COG3633   81 IIVLYLLGTfLAALVAVVASFLFP-------TTLTLVA----AAADLTPPGGIGEVLKTLLLNVVDNPVNALANANYIGI 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 164 IFFSVLFGLGLSSLPKETKepllKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAF 243
Cdd:COG3633  150 LAWAIGLGLALRHASDTTK----TVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATTGFSALLGYAHLLAVLVGCMLF 225
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 244 FALVVlgavarlcN-LRIWTLIRI---------LKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNL 313
Cdd:COG3633  226 VALVV--------NpLIVFLKIRRnpyplvftcLRESGITAFFTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINM 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 314 DGstlyqsiAAIFIAQL-------YGIELSLGQEIVLVLTLMVTSKGIAGVPGVSfvVLLATL--GSVGIPLE------G 378
Cdd:COG3633  298 AG-------AAITITVLtlaavhtLGIEVDLPTALLLSVVAAVSACGASGVAGGS--LLLIPLacSLFGISNDiamqvvA 368
                        410
                 ....*....|....*....
gi 727177637 379 LAFIAGVdrILDMARTALN 397
Cdd:COG3633  369 VGFIIGV--IQDSAETALN 385
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
4-397 5.01e-21

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 94.55  E-value: 5.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637   4 VKISLAWQILIALVLGIIVGAVLHNQTESREWLvsnilspaGDIFIRLIKMiVVPIVISTLIvgIAGVGDAKKLGRIGLK 83
Cdd:PRK13628  12 ARGSLVKQILIGLVLGILLALLSPPAAEAVGLL--------GTLFVGALKA-VAPILVFVLV--MASIANHKKGQKTNIR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637  84 TIIYFEVITTIAIVVGLTLANVFQPghgidmSTLTTVDisqyEKTTEQVQSGSHSLVATILSLIPSNVFSSMAKGDMLPI 163
Cdd:PRK13628  81 PILVLYLLGTFLAALVAVVASFLFP------STLVLVA----SAADISPPQGIVEVLKTLLLSLVDNPINALLNANYIGI 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 164 IFFSVLFGLGLSSLPKETKepllKVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANFGFASLLPLAKLVVLVYFAIAF 243
Cdd:PRK13628 151 LAWAIGLGLALRHASDTTK----NVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAGYAQLLAVLVGCMLF 226
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 244 FALVVlgavarlcN-LRIWTLIR---------ILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNL 313
Cdd:PRK13628 227 VALVV--------NpLIVFWKIRrnpyplvftCLRESGVTAFFTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINM 298
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 314 DGSTLYQSIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLE------GLAFIAGVdr 387
Cdd:PRK13628 299 AGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSLLLIPLACSLFGISNDiamqvvAVGFIIGV-- 376
                        410
                 ....*....|
gi 727177637 388 ILDMARTALN 397
Cdd:PRK13628 377 LQDSAETALN 386
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
143-419 9.70e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 62.76  E-value: 9.70e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 143 ILSLIPSNVfSSMAKGDMLPIIFFSVLFGLGLSSLPKETKEpllkVFKAVSESMFKVTHMIMRYAPIGVFGLISVTVANF 222
Cdd:PRK14695  45 LLKLVDSPV-NALLTANYIGILSWAVIFGIAMREASKNSKE----LLKTIADVTSKIVEWIINLAPFGILGLVFKTISDK 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 223 GFASLLPLAKLVVLVYFAIAFFALVVLGAVARLCNLR-----IWTLIRIlkdELILAYSTASSETVLPRIIEKMEAYGAP 297
Cdd:PRK14695 120 GVGSLANYGILLVLLVTTMLFVAPVVNPLIAFFFMRRnpyplVWNCLRV---SGVTAFFTRSSATNIPVNMKLCHDLGLN 196
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727177637 298 KSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIELSLGQEIVLVLTLMVTSKGIAGVPGVSFVV------LLATLGS 371
Cdd:PRK14695 197 PDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLipvacsLFGISND 276
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 727177637 372 VGIPLEGLAFIAGVdrILDMARTALNvvgNALAVLVIAKWEHQFDRKK 419
Cdd:PRK14695 277 IAIQIVGVGFVIGV--IQDSCETALN---SSTDVLFTAVAEYAATRKK 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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