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Conserved domains on  [gi|727167544|ref|WP_033637078|]
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MULTISPECIES: LPS assembly protein LptD [Serratia]

Protein Classification

LPS-assembly protein LptD( domain architecture ID 11480051)

LPS-assembly protein LptD, together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK03761 PRK03761
LPS assembly outer membrane complex protein LptD; Provisional
1-786 0e+00

LPS assembly outer membrane complex protein LptD; Provisional


:

Pssm-ID: 235158 [Multi-domain]  Cd Length: 778  Bit Score: 1492.11  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544   1 MKKSFPTLLATMIWTALYSQHALADLAEQCMLGVPVYDKPLVSGDPNSLPVTINADDSRADYPKSALFSGNVHIEQGNST 80
Cdd:PRK03761   1 MKKRSPTLLATMIATALYSQQALADLASQCMLGVPSYDRPLVTGDPNQLPVTIEADHAEANYPDDAVYTGNVDIKQGNSR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  81 LTAKEVELNQTQNPGQAEPVRTVTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQGRGDADKMKMRGANR 160
Cdd:PRK03761  81 LTADEVQLHQQENPGQAEPVRTVDALGNVHYDDNQIILKGPKAWSNLNTKDTNVWNGDYQMVGRQGRGKADLMKQRGQNR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 161 YTILENGTFTSCLPGDDSWSVVGSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRSGFLIPNAKYGSNNGF 240
Cdd:PRK03761 161 YTILENGSFTSCLPGDNSWSVVGSEIIHDREEEVAEIWNARFKVGGVPVFYSPYLQLPIGDKRRSGFLIPNAKYSSKNGF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 241 EFMLPYYWNIAPNYDATITPHYMSKRGLQWQTEFRYLVQPGLGLMEFDWLPDDKEYGKDH--DDSKRWLFYWNHNGVMDQ 318
Cdd:PRK03761 241 EFELPYYWNIAPNYDATITPHYMSRRGWQWENEFRYLTQAGAGLMAGEYLPSDRVYEDEPndDNSSRWLFYWNHSGVMDQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 319 VWRFNVDYTKVSDSKYFTDLDSKYGSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSqseSYKVQPQLDLNYYK 398
Cdd:PRK03761 321 VWRFNVDYTKVSDPRYFTDFDSKYGSSTDGYATQKFSVGYAQQNWNATLSTKQFQVFDEQNNS---PYRAEPQLDFNYYQ 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 399 NDLGPFDFHIYGQAAKFTSVNPYSPDATRLHMEPTLNLPLTNGWASLNTEAKVMATHYQQDIPDGFAANYqsrkgavAPE 478
Cdd:PRK03761 398 NDLGPFDFRLYGQAVRFTNDNKNMPEATRVHLEPTLNLPLSNRWGSLNTEAKLLATHYQQDNLDWYNSNN-------TTK 470
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 479 LDDSVNRVLPQFKVDGKLVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIAS 558
Cdd:PRK03761 471 LEESVNRVIPQFKVDGKMVFERDMDLAPGYTQTLEPRVQYLYVPYRDQSNIYNYDSTLLQSDYYGLFRDRTYSGLDRIAS 550
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 559 QNRVSTGLTTRIYDDALVERFNASVGQIYYFSRSRTGDQvTGYDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNS 638
Cdd:PRK03761 551 ANQVTTGVTTRFYDDAAVERFNISVGQIYYFTPSRTGDN-NTWENDDKTGSSVWAGDTYWRISDRWGLRGGIQYDTRLDS 629
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 639 VSLGNGVVEYRQDAERVVQLNYRYATPEYIQTALNTKT-VPAFQDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQ 717
Cdd:PRK03761 630 VALANSSLEYRRDEDRLIQLNYRYASPEYIQATLPSYYsAEIYQQGISQVGAVASWPIADRWSIVGAYYYDTKANKPAEQ 709
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544 718 LVGLKYNTCCWAVTLGYERKITDWNNSNNTSVYDNRVSFNVELRGLSSDHSLGSAEMLRSGILPYQRAF 786
Cdd:PRK03761 710 LLGLQYNSCCWAIGVGYERKLTGWDNDKQHSVYDNKIGFNIELRGLSSNYGLGTQEMLRSNILPYQRAF 778
 
Name Accession Description Interval E-value
PRK03761 PRK03761
LPS assembly outer membrane complex protein LptD; Provisional
1-786 0e+00

LPS assembly outer membrane complex protein LptD; Provisional


Pssm-ID: 235158 [Multi-domain]  Cd Length: 778  Bit Score: 1492.11  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544   1 MKKSFPTLLATMIWTALYSQHALADLAEQCMLGVPVYDKPLVSGDPNSLPVTINADDSRADYPKSALFSGNVHIEQGNST 80
Cdd:PRK03761   1 MKKRSPTLLATMIATALYSQQALADLASQCMLGVPSYDRPLVTGDPNQLPVTIEADHAEANYPDDAVYTGNVDIKQGNSR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  81 LTAKEVELNQTQNPGQAEPVRTVTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQGRGDADKMKMRGANR 160
Cdd:PRK03761  81 LTADEVQLHQQENPGQAEPVRTVDALGNVHYDDNQIILKGPKAWSNLNTKDTNVWNGDYQMVGRQGRGKADLMKQRGQNR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 161 YTILENGTFTSCLPGDDSWSVVGSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRSGFLIPNAKYGSNNGF 240
Cdd:PRK03761 161 YTILENGSFTSCLPGDNSWSVVGSEIIHDREEEVAEIWNARFKVGGVPVFYSPYLQLPIGDKRRSGFLIPNAKYSSKNGF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 241 EFMLPYYWNIAPNYDATITPHYMSKRGLQWQTEFRYLVQPGLGLMEFDWLPDDKEYGKDH--DDSKRWLFYWNHNGVMDQ 318
Cdd:PRK03761 241 EFELPYYWNIAPNYDATITPHYMSRRGWQWENEFRYLTQAGAGLMAGEYLPSDRVYEDEPndDNSSRWLFYWNHSGVMDQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 319 VWRFNVDYTKVSDSKYFTDLDSKYGSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSqseSYKVQPQLDLNYYK 398
Cdd:PRK03761 321 VWRFNVDYTKVSDPRYFTDFDSKYGSSTDGYATQKFSVGYAQQNWNATLSTKQFQVFDEQNNS---PYRAEPQLDFNYYQ 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 399 NDLGPFDFHIYGQAAKFTSVNPYSPDATRLHMEPTLNLPLTNGWASLNTEAKVMATHYQQDIPDGFAANYqsrkgavAPE 478
Cdd:PRK03761 398 NDLGPFDFRLYGQAVRFTNDNKNMPEATRVHLEPTLNLPLSNRWGSLNTEAKLLATHYQQDNLDWYNSNN-------TTK 470
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 479 LDDSVNRVLPQFKVDGKLVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIAS 558
Cdd:PRK03761 471 LEESVNRVIPQFKVDGKMVFERDMDLAPGYTQTLEPRVQYLYVPYRDQSNIYNYDSTLLQSDYYGLFRDRTYSGLDRIAS 550
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 559 QNRVSTGLTTRIYDDALVERFNASVGQIYYFSRSRTGDQvTGYDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNS 638
Cdd:PRK03761 551 ANQVTTGVTTRFYDDAAVERFNISVGQIYYFTPSRTGDN-NTWENDDKTGSSVWAGDTYWRISDRWGLRGGIQYDTRLDS 629
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 639 VSLGNGVVEYRQDAERVVQLNYRYATPEYIQTALNTKT-VPAFQDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQ 717
Cdd:PRK03761 630 VALANSSLEYRRDEDRLIQLNYRYASPEYIQATLPSYYsAEIYQQGISQVGAVASWPIADRWSIVGAYYYDTKANKPAEQ 709
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544 718 LVGLKYNTCCWAVTLGYERKITDWNNSNNTSVYDNRVSFNVELRGLSSDHSLGSAEMLRSGILPYQRAF 786
Cdd:PRK03761 710 LLGLQYNSCCWAIGVGYERKLTGWDNDKQHSVYDNKIGFNIELRGLSSNYGLGTQEMLRSNILPYQRAF 778
LptD COG1452
LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA) [Cell wall ...
24-765 0e+00

LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441061 [Multi-domain]  Cd Length: 702  Bit Score: 757.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  24 ADLAEQCmLGVPVYDkplvsgDPNSLPVTINADDSRAD-YPKSALFSGNVHIEQGNSTLTAKEVELNQTQNpgqaepvrT 102
Cdd:COG1452    1 AQDAAQA-LSVPDLA------PDDDAPVLIEADSLEYDqDDGTVTAEGNVEIRQGDRRLKADRVTYDQKTG--------T 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 103 VTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQGRGDADKMKMRGANRYTiLENGTFTSCLPGDDSWSVV 182
Cdd:COG1452   66 VTAEGNVRLTDGGNVLTGDEAELNLDTKDGFIENARYQLVDRGGRGAAERIKRTGDNRTR-LENATYTTCPPGDPDWQIR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 183 GSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRSGFLIPNAKYGSNNGFEFMLPYYWNIAPNYDATITPHY 262
Cdd:COG1452  145 ASRIILDQEEKVGTARNARLEIKGVPVFYLPYLSFPDPDKRKSGFLIPSFGSSSRLGFELSLPYYWNIAPNYDATLTPRY 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 263 MSKRGLQWQTEFRYLVQPGLG--LMEFDWLPDDKEYgkdhDDSKRWLFYWNHNGVMDQVWRFNVDYTKVSDSKYFTDLDS 340
Cdd:COG1452  225 MSKRGLQLGGEYRYLFKSGSGelSIRGEYLPDDRLG----DNDDRGLLRWQHSFDLNKGWRFGADVNRVSDDDYLRDFDS 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 341 KYGSTTDGYATQKFSL-GYANENWNATLSSKQFQIYDDTDRSQseSYKVQPQLDLNYYKNDLGPFDFHIYGQAAKFT--- 416
Cdd:COG1452  301 SLGSSSDDYLTSSASLsRTYGDNWNLSLRAQHFQTLRDSDDDS--PYQRLPQLDFNYVYRPLLGGEFSLDAEATNFTrdd 378
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 417 SVNPYSPDATRLHMEPTLNLPLTNGWA-SLNTEAKVMATHYQQDIPDGFAAnyqsrkgavapeLDDSVNRVLPQFKVDGK 495
Cdd:COG1452  379 SDFQDGPDGTRLHLEPSWSLPLSRPGGlFLTPKAGLRATAYQLDNDSDPDT------------LDGSVSRVLPTFSLDSG 446
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 496 LVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIASQNRVSTGLTTRIYDDA- 574
Cdd:COG1452  447 LPFERDFSLGGGGTQTLEPRLQYLYVPYRDQSDIPNFDSALLDFDYANLFSDNRFSGYDRIEDGNQLTLGLTSRLLDKDg 526
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 575 LVERFNASVGQIYYFSRSRTGDqvtgyDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNSVSLGNGVVEYRQDAeR 654
Cdd:COG1452  527 GRERLRLSVGQSYYFADQRTLA-----DDSGSTKLSDLVAEASLRPNDGLSLTARAQYDPYTGRVNRGNAGLRYRPDR-R 600
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 655 VVQLNYRYATPEYIqtalntktvPAFQDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQLVGLKYNTCCWAVTLGY 734
Cdd:COG1452  601 NLNLGYRYLRDDPD---------YGYSDDIEQLDLSGSWPLTDNWSVVGRYRYDLTDNRLVETLLGLEYDDCCWALRLVY 671
                        730       740       750
                 ....*....|....*....|....*....|.
gi 727167544 735 ERKITDwnnsNNTSVYDNRVSFNVELRGLSS 765
Cdd:COG1452  672 RRYYTS----GSDLEYDTSFFFQLELKGLGS 698
LptD pfam04453
LPS transport system D; Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria ...
305-699 7.46e-118

LPS transport system D; Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria and has crucial roles in protection of the bacteria from harsh environments and toxic compounds, including antibiotics. This family includes members such as LPTD found in Shigella flexneri and Yersinia pestis. Structural analysis indicates that LptD forms a novel 26-stranded beta-barrel. It interacts with LPTE where LptE adopts a roll-like structure located inside the barrel of LptD. The LPS translocon LptD is unable to fold properly in the absence of LptE and the two proteins form a unique barrel and plug architecture for LPS transport and insertion. LptD is an essential outer membrane protein that mediates the final transport of lipopolysaccharide (LPS) to outer leaflet. It has been suggested that LptD is a promising target for the development of effective vaccines and antibody-based therapies to control Vibrio infection.


Pssm-ID: 427958  Cd Length: 384  Bit Score: 360.95  E-value: 7.46e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  305 RWLFYWNHNGVMDQVWRFNVDYTKVSDSKYFTDLDSKYGSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSQSE 384
Cdd:pfam04453   3 RGYFNASHQFILNDNWSFGVDYNYVSDKNYFRDYDSNIGLVSQTYLLRQGRLSYRNDNWDFSLRVQDYQTLDPTIISNDT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  385 SYKVQPQLDLNYYKNDL--GPFDFHIYGQAAKFTSVNPYSPDATRLHMEPTLNLPLTNGWASLNTEAKVMATHYQQDIPD 462
Cdd:pfam04453  83 PYQRLPQLDYNYYKPDPgfGGLDFSFDSQYVRFSRDDGQQPTGTRLHLEPEISLPFTNPWGFLTPELKLRGTAYDLDVDL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  463 GFAANYQSrkgavapELDDSVNRVLPQFKVDGKLVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYS 542
Cdd:pfam04453 163 GPGENATG-------GLDSSVTRVLPTFSLDSGLPFERDTTLFGDYTQTLEPRAQYLYVPYRDQNNLPNYDSSSLDFDYT 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  543 GLFRDRTYSGLDRIASQNRVSTGLTTRIYDDA-LVERFNASVGQIYYFSRSRTGDQVTGYDNNDDTGsvAWAGDTYWKID 621
Cdd:pfam04453 236 NLFRDNRFSGYDRIEDANQLTYGVTSRFFDANgGFERLRLSVGQSFYFTDRRVFLIGDESGLTRRSS--DLVAELSFSPN 313
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727167544  622 DRWGLRGGLQYDTRLNSVSLGNGVVEYRQDAERVVQLNYRYATPEYIQTalntktvPAFQDGISQVGITGSWPIADRW 699
Cdd:pfam04453 314 RGLNLSASIQYDPYTNNFERGEVGLSYRPDRGNSINLGYRYRRNDPEYQ-------NATNNGISQIGLSAQWPLADNW 384
outer_YhbN_LptA TIGR03002
lipopolysaccharide transport periplasmic protein LptA; Members of this protein family include ...
50-126 6.20e-05

lipopolysaccharide transport periplasmic protein LptA; Members of this protein family include LptA (previously called YhbN). It was shown to be an essential protein in E. coli, implicated in cell envelope integrity, and to play a role in the delivery of LPS to the outer leaflet of the outer membrane. It works with LptB (formerly yhbG), a homolog of ABC transporter ATP-binding proteins, encoded by an adjacent gene. Numerous homologs in other Proteobacteria are found in a conserved location near lipopolysaccharide inner core biosynthesis genes. This family is related to organic solvent tolerance protein (OstA), though distantly. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 274384 [Multi-domain]  Cd Length: 142  Bit Score: 43.75  E-value: 6.20e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544   50 PVTINADDSRADYPKS-ALFSGNVHIEQGNSTLTAKEVELNQTQNPGqaepVRTVTATGD-VHYSDNQIKLKGPKAWSN 126
Cdd:TIGR03002   9 PIHIEADSQTLDDKKGvVTFTGNVVITQGTLKIRADKVVVTRNDAGG----IEKATATGKpATFRQKLDNGKEIEGQAN 83
 
Name Accession Description Interval E-value
PRK03761 PRK03761
LPS assembly outer membrane complex protein LptD; Provisional
1-786 0e+00

LPS assembly outer membrane complex protein LptD; Provisional


Pssm-ID: 235158 [Multi-domain]  Cd Length: 778  Bit Score: 1492.11  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544   1 MKKSFPTLLATMIWTALYSQHALADLAEQCMLGVPVYDKPLVSGDPNSLPVTINADDSRADYPKSALFSGNVHIEQGNST 80
Cdd:PRK03761   1 MKKRSPTLLATMIATALYSQQALADLASQCMLGVPSYDRPLVTGDPNQLPVTIEADHAEANYPDDAVYTGNVDIKQGNSR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  81 LTAKEVELNQTQNPGQAEPVRTVTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQGRGDADKMKMRGANR 160
Cdd:PRK03761  81 LTADEVQLHQQENPGQAEPVRTVDALGNVHYDDNQIILKGPKAWSNLNTKDTNVWNGDYQMVGRQGRGKADLMKQRGQNR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 161 YTILENGTFTSCLPGDDSWSVVGSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRSGFLIPNAKYGSNNGF 240
Cdd:PRK03761 161 YTILENGSFTSCLPGDNSWSVVGSEIIHDREEEVAEIWNARFKVGGVPVFYSPYLQLPIGDKRRSGFLIPNAKYSSKNGF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 241 EFMLPYYWNIAPNYDATITPHYMSKRGLQWQTEFRYLVQPGLGLMEFDWLPDDKEYGKDH--DDSKRWLFYWNHNGVMDQ 318
Cdd:PRK03761 241 EFELPYYWNIAPNYDATITPHYMSRRGWQWENEFRYLTQAGAGLMAGEYLPSDRVYEDEPndDNSSRWLFYWNHSGVMDQ 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 319 VWRFNVDYTKVSDSKYFTDLDSKYGSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSqseSYKVQPQLDLNYYK 398
Cdd:PRK03761 321 VWRFNVDYTKVSDPRYFTDFDSKYGSSTDGYATQKFSVGYAQQNWNATLSTKQFQVFDEQNNS---PYRAEPQLDFNYYQ 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 399 NDLGPFDFHIYGQAAKFTSVNPYSPDATRLHMEPTLNLPLTNGWASLNTEAKVMATHYQQDIPDGFAANYqsrkgavAPE 478
Cdd:PRK03761 398 NDLGPFDFRLYGQAVRFTNDNKNMPEATRVHLEPTLNLPLSNRWGSLNTEAKLLATHYQQDNLDWYNSNN-------TTK 470
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 479 LDDSVNRVLPQFKVDGKLVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIAS 558
Cdd:PRK03761 471 LEESVNRVIPQFKVDGKMVFERDMDLAPGYTQTLEPRVQYLYVPYRDQSNIYNYDSTLLQSDYYGLFRDRTYSGLDRIAS 550
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 559 QNRVSTGLTTRIYDDALVERFNASVGQIYYFSRSRTGDQvTGYDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNS 638
Cdd:PRK03761 551 ANQVTTGVTTRFYDDAAVERFNISVGQIYYFTPSRTGDN-NTWENDDKTGSSVWAGDTYWRISDRWGLRGGIQYDTRLDS 629
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 639 VSLGNGVVEYRQDAERVVQLNYRYATPEYIQTALNTKT-VPAFQDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQ 717
Cdd:PRK03761 630 VALANSSLEYRRDEDRLIQLNYRYASPEYIQATLPSYYsAEIYQQGISQVGAVASWPIADRWSIVGAYYYDTKANKPAEQ 709
                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544 718 LVGLKYNTCCWAVTLGYERKITDWNNSNNTSVYDNRVSFNVELRGLSSDHSLGSAEMLRSGILPYQRAF 786
Cdd:PRK03761 710 LLGLQYNSCCWAIGVGYERKLTGWDNDKQHSVYDNKIGFNIELRGLSSNYGLGTQEMLRSNILPYQRAF 778
LptD COG1452
LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA) [Cell wall ...
24-765 0e+00

LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441061 [Multi-domain]  Cd Length: 702  Bit Score: 757.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  24 ADLAEQCmLGVPVYDkplvsgDPNSLPVTINADDSRAD-YPKSALFSGNVHIEQGNSTLTAKEVELNQTQNpgqaepvrT 102
Cdd:COG1452    1 AQDAAQA-LSVPDLA------PDDDAPVLIEADSLEYDqDDGTVTAEGNVEIRQGDRRLKADRVTYDQKTG--------T 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 103 VTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQGRGDADKMKMRGANRYTiLENGTFTSCLPGDDSWSVV 182
Cdd:COG1452   66 VTAEGNVRLTDGGNVLTGDEAELNLDTKDGFIENARYQLVDRGGRGAAERIKRTGDNRTR-LENATYTTCPPGDPDWQIR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 183 GSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRSGFLIPNAKYGSNNGFEFMLPYYWNIAPNYDATITPHY 262
Cdd:COG1452  145 ASRIILDQEEKVGTARNARLEIKGVPVFYLPYLSFPDPDKRKSGFLIPSFGSSSRLGFELSLPYYWNIAPNYDATLTPRY 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 263 MSKRGLQWQTEFRYLVQPGLG--LMEFDWLPDDKEYgkdhDDSKRWLFYWNHNGVMDQVWRFNVDYTKVSDSKYFTDLDS 340
Cdd:COG1452  225 MSKRGLQLGGEYRYLFKSGSGelSIRGEYLPDDRLG----DNDDRGLLRWQHSFDLNKGWRFGADVNRVSDDDYLRDFDS 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 341 KYGSTTDGYATQKFSL-GYANENWNATLSSKQFQIYDDTDRSQseSYKVQPQLDLNYYKNDLGPFDFHIYGQAAKFT--- 416
Cdd:COG1452  301 SLGSSSDDYLTSSASLsRTYGDNWNLSLRAQHFQTLRDSDDDS--PYQRLPQLDFNYVYRPLLGGEFSLDAEATNFTrdd 378
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 417 SVNPYSPDATRLHMEPTLNLPLTNGWA-SLNTEAKVMATHYQQDIPDGFAAnyqsrkgavapeLDDSVNRVLPQFKVDGK 495
Cdd:COG1452  379 SDFQDGPDGTRLHLEPSWSLPLSRPGGlFLTPKAGLRATAYQLDNDSDPDT------------LDGSVSRVLPTFSLDSG 446
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 496 LVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIASQNRVSTGLTTRIYDDA- 574
Cdd:COG1452  447 LPFERDFSLGGGGTQTLEPRLQYLYVPYRDQSDIPNFDSALLDFDYANLFSDNRFSGYDRIEDGNQLTLGLTSRLLDKDg 526
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 575 LVERFNASVGQIYYFSRSRTGDqvtgyDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNSVSLGNGVVEYRQDAeR 654
Cdd:COG1452  527 GRERLRLSVGQSYYFADQRTLA-----DDSGSTKLSDLVAEASLRPNDGLSLTARAQYDPYTGRVNRGNAGLRYRPDR-R 600
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 655 VVQLNYRYATPEYIqtalntktvPAFQDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQLVGLKYNTCCWAVTLGY 734
Cdd:COG1452  601 NLNLGYRYLRDDPD---------YGYSDDIEQLDLSGSWPLTDNWSVVGRYRYDLTDNRLVETLLGLEYDDCCWALRLVY 671
                        730       740       750
                 ....*....|....*....|....*....|.
gi 727167544 735 ERKITDwnnsNNTSVYDNRVSFNVELRGLSS 765
Cdd:COG1452  672 RRYYTS----GSDLEYDTSFFFQLELKGLGS 698
LptD pfam04453
LPS transport system D; Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria ...
305-699 7.46e-118

LPS transport system D; Lipopolysaccharide (LPS) is essential for most Gram-negative bacteria and has crucial roles in protection of the bacteria from harsh environments and toxic compounds, including antibiotics. This family includes members such as LPTD found in Shigella flexneri and Yersinia pestis. Structural analysis indicates that LptD forms a novel 26-stranded beta-barrel. It interacts with LPTE where LptE adopts a roll-like structure located inside the barrel of LptD. The LPS translocon LptD is unable to fold properly in the absence of LptE and the two proteins form a unique barrel and plug architecture for LPS transport and insertion. LptD is an essential outer membrane protein that mediates the final transport of lipopolysaccharide (LPS) to outer leaflet. It has been suggested that LptD is a promising target for the development of effective vaccines and antibody-based therapies to control Vibrio infection.


Pssm-ID: 427958  Cd Length: 384  Bit Score: 360.95  E-value: 7.46e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  305 RWLFYWNHNGVMDQVWRFNVDYTKVSDSKYFTDLDSKYGSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSQSE 384
Cdd:pfam04453   3 RGYFNASHQFILNDNWSFGVDYNYVSDKNYFRDYDSNIGLVSQTYLLRQGRLSYRNDNWDFSLRVQDYQTLDPTIISNDT 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  385 SYKVQPQLDLNYYKNDL--GPFDFHIYGQAAKFTSVNPYSPDATRLHMEPTLNLPLTNGWASLNTEAKVMATHYQQDIPD 462
Cdd:pfam04453  83 PYQRLPQLDYNYYKPDPgfGGLDFSFDSQYVRFSRDDGQQPTGTRLHLEPEISLPFTNPWGFLTPELKLRGTAYDLDVDL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  463 GFAANYQSrkgavapELDDSVNRVLPQFKVDGKLVFERPMIWAEGATQTLEPRVQYLYVPYRDQSNIYTYDTTLLQTDYS 542
Cdd:pfam04453 163 GPGENATG-------GLDSSVTRVLPTFSLDSGLPFERDTTLFGDYTQTLEPRAQYLYVPYRDQNNLPNYDSSSLDFDYT 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  543 GLFRDRTYSGLDRIASQNRVSTGLTTRIYDDA-LVERFNASVGQIYYFSRSRTGDQVTGYDNNDDTGsvAWAGDTYWKID 621
Cdd:pfam04453 236 NLFRDNRFSGYDRIEDANQLTYGVTSRFFDANgGFERLRLSVGQSFYFTDRRVFLIGDESGLTRRSS--DLVAELSFSPN 313
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 727167544  622 DRWGLRGGLQYDTRLNSVSLGNGVVEYRQDAERVVQLNYRYATPEYIQTalntktvPAFQDGISQVGITGSWPIADRW 699
Cdd:pfam04453 314 RGLNLSASIQYDPYTNNFERGEVGLSYRPDRGNSINLGYRYRRNDPEYQ-------NATNNGISQIGLSAQWPLADNW 384
PRK04423 PRK04423
LPS-assembly protein LptD;
67-784 3.32e-101

LPS-assembly protein LptD;


Pssm-ID: 235297 [Multi-domain]  Cd Length: 798  Bit Score: 330.30  E-value: 3.32e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  67 LFSGNVHIEQGNSTLTAKEVELN-QTQNpgqaepvrtVTATGDVHYSDNQIKLKGPKAWSNLNTKDTDVYEGDYQMVGRQ 145
Cdd:PRK04423  75 QYQGNVALKRGDQFLGADNLRMDtETGN---------YIAEGNVRYQDTSIRMVADRAEGNQDTDTHKITNIQYQLVSRR 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 146 GRGDADKMKMRGAnrYTILENGTFTSCLPGDDSWSVVGSEVIHDREEQVAEVWNARFRIGGVPVFYSPYLQLPVGDKRRS 225
Cdd:PRK04423 146 GNGDAESVDLQGQ--VGQMHRSTYTTCDPSQPIWRLRAPEIDVDNDEGFGTARNAVLQIGKVPVLYFPWFKFPIDDRRQT 223
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 226 GFLIPNAKYGSNNGFEFMLPYYWNIAPNYDATITPHYMSKRGLQWQTEFRYLVQPGLGLMEFDWLPDDKEYGKDHDdskR 305
Cdd:PRK04423 224 GLLFPQFGLSGRNGFDYLQPIYLNLAPNYDATLLPRYMSKRGFMFGTEFRYLYDGGRGEVTGNYLPNDKLRDKDRG---R 300
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 306 WLFYWNHNgvMDQVWRFNVDYTKVSDSKYFTDLDSKY-GSTTDGYATQKFSLGYANENWNATLSSKQFQIYDDTDRSQSE 384
Cdd:PRK04423 301 VFYSGYHN--VNSHWQARASLSWVSDTRYVEDFTSRLnGMGSASSLQSTVGIYGTGETWTAGLMADRWQLTDYTLDERAL 378
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 385 SYKVQPQLDLNYYKNDLGPFDFHIYGQAAKFTS----------------------VNPYSPDATRLHMEPTLNLPLTNGW 442
Cdd:PRK04423 379 PYNRQPRAYFNWEKPVFGIFEAGVYAEAVRFTHddsylvqppndgdddnyvrtgiVNREYGSGSRLDVKPYVSMPLSGAA 458
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 443 ASLNTEAKVMATHYQQDipDGFAANYQSRKgavapelDDSVNRVLPQFKVDGKLVFERPM-IWAEGATQTLEPRVQYLYV 521
Cdd:PRK04423 459 WFVTPTLAWRYTAYQLD--STLAETAPLTG-------DRSPSRSLPIASLDAGLYFDRETsLFGTNYLNTLEPRLYYLYV 529
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 522 PYRDQSNIYTYDTTLLQTDYSGLFRDRTYSGLDRIASQNRVSTGLTTRIYD-DALVERFNASVGQIYYFSRSRTgdQVTG 600
Cdd:PRK04423 530 PYRNQDDLPVFDTRPFTFSWGQLFRDSRYTGADRQNDANQLTLAVTSRWLRqDDGKEKLSLSAGQILYFDDSLV--TINN 607
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 601 YDNNDDTGSVAWAGDTYWKIDDRWGLRGGLQYDTRLNSVSLGNGVVEYRQDAERVVQLNYRYatpeyiqtalnTKTVPAF 680
Cdd:PRK04423 608 SEQTIEQGKSAWVADANYMINDRWTLGATYQWNPNSRREDLASLRTRYLLPNDGIINLAYRY-----------RRNLIDN 676
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544 681 QDGISQVGITGSWPIADRWAVVGAYYYDTRAKQSADQLVGLKYNTCCWAVTLGYERKItdwnnSNNTSVYDNRVSFNVEL 760
Cdd:PRK04423 677 SDQLKQADFSFLYPINPRWSAVGRYYYSLLDKKPLEIIGGVQWDSCCLAVRALVRRFV-----RNRDGEMDNSIQIEFVL 751
                        730       740
                 ....*....|....*....|....*.
gi 727167544 761 RGLSsdhSLG--SAEMLRSGILPYQR 784
Cdd:PRK04423 752 KGLS---SFGqdTDRTLRRAILGYYR 774
LptD_N pfam03968
LptA/(LptD N-terminal domain) LPS transport protein; This family of proteins are involved in ...
52-194 1.29e-21

LptA/(LptD N-terminal domain) LPS transport protein; This family of proteins are involved in lipopolysaccharide transport across the gram negative inner and outer membranes. The type examples for this family are E. coli LptA and the N-terminal domain of LptD.


Pssm-ID: 427621 [Multi-domain]  Cd Length: 113  Bit Score: 90.38  E-value: 1.29e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544   52 TINADDSRADYPKS-ALFSGNVHIEQGNSTLTAKEVELNQTQNPGQaepvrtvtatgdvhysdnqiklkgpkaWSNLNTK 130
Cdd:pfam03968   1 EIEADNAELDDKKNvATFTGNVIVTQGTLTLRADKVIVTQDKKKNG---------------------------PERLEAT 53
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 727167544  131 DTDVYEGDYQMVGRQGRGDADKMKMRGANRYTILE-NGTFTsclpgDDSWSVVGSEVIHDREEQV 194
Cdd:pfam03968  54 GPATFRQKVDLVGRPIRGKADRIEYDVAKDIIVLTgNARLT-----QGGNSVRGDKITYDIKEQK 113
LptA COG1934
Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];
50-197 4.75e-11

Lipopolysaccharide export system protein LptA [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441537 [Multi-domain]  Cd Length: 164  Bit Score: 61.86  E-value: 4.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  50 PVTINADDSRADYPK-SALFSGNVHIEQGNSTLTAKEVELNQTQNPGqaepVRTVTATGDVHYSDNQIKLKGPKAWSNln 128
Cdd:COG1934   25 PIEIEADRLEVDDKKgTAVFTGNVVVTQGTLTLRADKLVVYYDKAGG----IERIEATGNVTFRQKRDGGQEVEATAD-- 98
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544 129 tkdtdvyEGDYQMvgrqgrgDADKMKMRGanrytileNGTFTSclpGDDswSVVGSEVIHDREEQVAEV 197
Cdd:COG1934   99 -------RAEYDV-------ATDTVVLTG--------NAVLTQ---GGN--TVTGDRITYDLKTGRATA 140
outer_YhbN_LptA TIGR03002
lipopolysaccharide transport periplasmic protein LptA; Members of this protein family include ...
50-126 6.20e-05

lipopolysaccharide transport periplasmic protein LptA; Members of this protein family include LptA (previously called YhbN). It was shown to be an essential protein in E. coli, implicated in cell envelope integrity, and to play a role in the delivery of LPS to the outer leaflet of the outer membrane. It works with LptB (formerly yhbG), a homolog of ABC transporter ATP-binding proteins, encoded by an adjacent gene. Numerous homologs in other Proteobacteria are found in a conserved location near lipopolysaccharide inner core biosynthesis genes. This family is related to organic solvent tolerance protein (OstA), though distantly. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 274384 [Multi-domain]  Cd Length: 142  Bit Score: 43.75  E-value: 6.20e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 727167544   50 PVTINADDSRADYPKS-ALFSGNVHIEQGNSTLTAKEVELNQTQNPGqaepVRTVTATGD-VHYSDNQIKLKGPKAWSN 126
Cdd:TIGR03002   9 PIHIEADSQTLDDKKGvVTFTGNVVITQGTLKIRADKVVVTRNDAGG----IEKATATGKpATFRQKLDNGKEIEGQAN 83
LptD_2 pfam19838
LptD protein; This entry likely represents the LptD homolog of Bacteriodetes bacteria. LptD is ...
200-313 5.56e-03

LptD protein; This entry likely represents the LptD homolog of Bacteriodetes bacteria. LptD is an essential outer membrane protein that mediates the final transport of lipopolysaccharide (LPS) to outer leaflet.


Pssm-ID: 466203  Cd Length: 474  Bit Score: 39.85  E-value: 5.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 727167544  200 ARFRIGGVPVfyspYLQLPVG------DKRRSGFLIPnaKYGSNN--GFeFM--LPYYWNIAPNYDATITPHYMSKRGLQ 269
Cdd:pfam19838   6 ANLYIEDVPT----PLGLPFGffpltsGRRRSGIIIP--TYGESNdrGF-FLrnGGYYFAINDYFDLTLTGDIYTKGSWG 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 727167544  270 WQTEFRYLV----QPGLGLmEFDWLPDDKEYGKDHDDSKRWLFYWNHN 313
Cdd:pfam19838  79 LNAESRYKKrykySGNFNL-SYSNNKRGEKGLPDYSKTKDFNIRWSHS 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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