|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
146-714 |
1.10e-176 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 520.87 E-value: 1.10e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 146 ALIDQHGRELAGEKNIYAGISQTRNGVAFVGIGLIRPMVGSLQIHDGTRRYLVITRHLNARILSDLGGTFQIDNLHFTPG 225
Cdd:COG5001 97 LALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARALLALLLLLLLALLLLL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 226 KINDRSMPLHSAAGELVGYLNWQARLPGAQAARAASSDIRQIVVLVSGLILLFILVSSVGLYKLARGESQARLVARTDWL 305
Cdd:COG5001 177 LLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITERKRAEERLRHLAYHDPL 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 306 SHLPNRRALIETLDRV---RLRGDTDVkSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFA 382
Cdd:COG5001 257 TGLPNRRLFLDRLEQAlarARRSGRRL-ALLFIDLDRFKEINDTLGHAAGDELLREVARRLRACLREGDTVARLGGDEFA 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 383 MTIGGDDAEAQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRITHYDAE 462
Cdd:COG5001 336 VLLPDLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMYRAKAAGRNRYRFFDPE 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 463 LNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWpRRPE-GPLGPDTFIAIAETSGLIYKLGQFVL 541
Cdd:COG5001 416 MDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRW-QHPErGLVSPAEFIPLAEETGLIVPLGEWVL 494
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 542 QRACEDL-----QPYGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGT 616
Cdd:COG5001 495 REACRQLaawqdAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDPEEALETLRALRALGV 574
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 617 AVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQ 696
Cdd:COG5001 575 RIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVETEEQLEFLRELGCDY 654
|
570
....*....|....*...
gi 697052767 697 LQGFWFSQPMPIESIKAL 714
Cdd:COG5001 655 AQGYLFSRPLPAEELEAL 672
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
475-709 |
1.10e-96 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 298.69 E-value: 1.10e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 475 NQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL----QP 550
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLarwqAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 551 YGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSI 630
Cdd:cd01948 81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052767 631 GYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIE 709
Cdd:cd01948 161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
272-719 |
1.34e-93 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 304.68 E-value: 1.34e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 272 SGLILLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRRALIETL-DRVRLRGDTDVkSVVFIDLDGFKDVNDIYGHS 350
Cdd:PRK10060 209 SGKNEIFLICSGTDITEERRAQERLRILANTDSITGLPNRNAIQELIdHAINAADNNQV-GIVYLDLDNFKKVNDAYGHM 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 351 VGDDLIVAIAKTLNERVPPGGMLARMGGDEF-AMTIGGDDAEAQATAfaVSVLDFLTTPVQLGERTIHIGASIGIASGTL 429
Cdd:PRK10060 288 FGDQLLQDVSLAILSCLEEDQTLARLGGDEFlVLASHTSQAALEAMA--SRILTRLRLPFRIGLIEVYTGCSIGIALAPE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 430 TECNSSELFRRADIAMYHAKMSGKGRITHYDAELNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQtMSSVEALVR 509
Cdd:PRK10060 366 HGDDSESLIRSADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGE-VRSLEALVR 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 510 W--PRRpeGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPYGE----LKLSVNISPAQFRDPAFEEKVASVLESTRF 583
Cdd:PRK10060 445 WqsPER--GLIPPLEFISYAEESGLIVPLGRWVMLDVVRQVAKWRDkginLRVAVNVSARQLADQTIFTALKQALQELNF 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 584 PANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSG 663
Cdd:PRK10060 523 EYCPIDVELTESCLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRA 602
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 697052767 664 TVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIESIKALRKVRR 719
Cdd:PRK10060 603 IVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYKRYL 658
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
474-709 |
2.34e-88 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 277.18 E-value: 2.34e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 474 ENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPY-- 551
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWqa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 552 ---GELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYS 628
Cdd:smart00052 81 qgpPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 629 SIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPI 708
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
.
gi 697052767 709 E 709
Cdd:smart00052 241 D 241
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
474-705 |
1.74e-75 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 242.99 E-value: 1.74e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 474 ENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL---QP 550
Cdd:pfam00563 1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLaqlQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 551 YGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSI 630
Cdd:pfam00563 81 GPDIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052767 631 GYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQP 705
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
300-456 |
2.70e-27 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 108.58 E-value: 2.70e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMG 377
Cdd:TIGR00254 2 AVRDPLTGLYNRRYLEEMLDSELKRARRFQRsfSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRYG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 378 GDEFAMTIGGDDAEaQATAFAVSV---LDFLTTPVQLGErTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKG 454
Cdd:TIGR00254 82 GEEFVVILPGTPLE-DALSKAERLrdaINSKPIEVAGSE-TLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRN 159
|
..
gi 697052767 455 RI 456
Cdd:TIGR00254 160 RV 161
|
|
| CHASE4 |
pfam05228 |
CHASE4 domain; CHASE4. This is an extracellular sensory domain, which is present in various ... |
61-212 |
2.05e-06 |
|
CHASE4 domain; CHASE4. This is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in prokaryotes. Specifically, CHASE4 domains are found in histidine kinases in Archaea and in predicted diguanylate cyclases/phosphodiesterases in Bacteria. Environmental factors that are recognized by CHASE4 domains are not known at this time.
Pssm-ID: 428380 Cd Length: 139 Bit Score: 47.71 E-value: 2.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 61 SIQTSVNRVSSLVLDNAVWDDAVREAYRPtlDTDWLYNTWGTGFKINNLYDGTFVLDEHFNVLWgsfqsrpfNEKNLDFF 140
Cdd:pfam05228 1 ALEQELDSLDRLLRDWAVWDDTYDFVQDG--NPDYIESNLGPETFENLGLDLILFVDADGKLVY--------DLENGKPD 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052767 141 GKGLKALIDQHGRelagekniyAGISQTRNGVAFVGIGLIRPMVGSLQIHDgtrrYLVITRHLNARILSDLG 212
Cdd:pfam05228 71 SPLLSRSSPDSGL---------SGIVLLGGGPALVAARPILTSDGSGPPRG----TLVMGRYLDEAFLDRLS 129
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
146-714 |
1.10e-176 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 520.87 E-value: 1.10e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 146 ALIDQHGRELAGEKNIYAGISQTRNGVAFVGIGLIRPMVGSLQIHDGTRRYLVITRHLNARILSDLGGTFQIDNLHFTPG 225
Cdd:COG5001 97 LALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARALLALLLLLLLALLLLL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 226 KINDRSMPLHSAAGELVGYLNWQARLPGAQAARAASSDIRQIVVLVSGLILLFILVSSVGLYKLARGESQARLVARTDWL 305
Cdd:COG5001 177 LLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITERKRAEERLRHLAYHDPL 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 306 SHLPNRRALIETLDRV---RLRGDTDVkSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFA 382
Cdd:COG5001 257 TGLPNRRLFLDRLEQAlarARRSGRRL-ALLFIDLDRFKEINDTLGHAAGDELLREVARRLRACLREGDTVARLGGDEFA 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 383 MTIGGDDAEAQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRITHYDAE 462
Cdd:COG5001 336 VLLPDLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMYRAKAAGRNRYRFFDPE 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 463 LNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWpRRPE-GPLGPDTFIAIAETSGLIYKLGQFVL 541
Cdd:COG5001 416 MDERARERLELEADLRRALERGELELHYQPQVDLATGRIVGAEALLRW-QHPErGLVSPAEFIPLAEETGLIVPLGEWVL 494
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 542 QRACEDL-----QPYGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGT 616
Cdd:COG5001 495 REACRQLaawqdAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDPEEALETLRALRALGV 574
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 617 AVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQ 696
Cdd:COG5001 575 RIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVETEEQLEFLRELGCDY 654
|
570
....*....|....*...
gi 697052767 697 LQGFWFSQPMPIESIKAL 714
Cdd:COG5001 655 AQGYLFSRPLPAEELEAL 672
|
|
| EAL |
COG2200 |
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ... |
179-714 |
1.33e-103 |
|
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];
Pssm-ID: 441802 [Multi-domain] Cd Length: 576 Bit Score: 328.67 E-value: 1.33e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 179 LIRPMVGSLQIHDGTRRYLVITRHLNARILSDLGGTFQIDNLHFTPGKINDRSMPLHSAAGELVGYLNWQARLPGAQAAR 258
Cdd:COG2200 35 LALASALLLAVAALLAALLAALLLLLALALLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLLLLLLLALLLAALLALL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 259 AASSDIRQIVVLVSGLILLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRRALIETLDRVRLRGDTDVKSVVFIDLD 338
Cdd:COG2200 115 LLLLLLLLLLLLSLLLLLVLVLLRLALELLLALLLLALLALLDLLLLLLLRRLLLLLLLLLLLLLLALALLALLLLLLLL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 339 GFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFAMTIGGDDAEAQATAFAVSVLDFLTTPVQLGERTIHI 418
Cdd:COG2200 195 LLLLLDNDGLGGAGLLLLLLLALLLLLLLARLLLALLGGGGGGFLLLLLLLAAAAAAAAALRLLLLLLLEPLLLGGGLVV 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 419 GASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRITHYDAELNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARS 498
Cdd:COG2200 275 VASSGGGAAAPDDGADAALLLAAAAAAAAAAAGGGRGRVVFFAAAEARARRRLALESELREALEEGELRLYYQPIVDLRT 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 499 QTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL----QPYGELKLSVNISPAQFRDPAFEEKV 574
Cdd:COG2200 355 GRVVGYEALLRWRHPDGGLISPAEFIPAAERSGLIVELDRWVLERALRQLarwpERGLDLRLSVNLSARSLLDPDFLERL 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 575 ASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDND 654
Cdd:COG2200 435 LELLAEYGLPPERLVLEITESALLEDLEAAIELLARLRALGVRIALDDFGTGYSSLSYLKRLPPDYLKIDRSFVRDIARD 514
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 655 EQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIESIKAL 714
Cdd:COG2200 515 PRDQAIVRAIVALAHRLGLKVVAEGVETEEQLEALRELGCDYAQGYLFGRPLPLEELEAL 574
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
475-709 |
1.10e-96 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 298.69 E-value: 1.10e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 475 NQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL----QP 550
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRTGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLarwqAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 551 YGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSI 630
Cdd:cd01948 81 GPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052767 631 GYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIE 709
Cdd:cd01948 161 SYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
272-719 |
1.34e-93 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 304.68 E-value: 1.34e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 272 SGLILLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRRALIETL-DRVRLRGDTDVkSVVFIDLDGFKDVNDIYGHS 350
Cdd:PRK10060 209 SGKNEIFLICSGTDITEERRAQERLRILANTDSITGLPNRNAIQELIdHAINAADNNQV-GIVYLDLDNFKKVNDAYGHM 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 351 VGDDLIVAIAKTLNERVPPGGMLARMGGDEF-AMTIGGDDAEAQATAfaVSVLDFLTTPVQLGERTIHIGASIGIASGTL 429
Cdd:PRK10060 288 FGDQLLQDVSLAILSCLEEDQTLARLGGDEFlVLASHTSQAALEAMA--SRILTRLRLPFRIGLIEVYTGCSIGIALAPE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 430 TECNSSELFRRADIAMYHAKMSGKGRITHYDAELNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQtMSSVEALVR 509
Cdd:PRK10060 366 HGDDSESLIRSADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGE-VRSLEALVR 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 510 W--PRRpeGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPYGE----LKLSVNISPAQFRDPAFEEKVASVLESTRF 583
Cdd:PRK10060 445 WqsPER--GLIPPLEFISYAEESGLIVPLGRWVMLDVVRQVAKWRDkginLRVAVNVSARQLADQTIFTALKQALQELNF 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 584 PANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSG 663
Cdd:PRK10060 523 EYCPIDVELTESCLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRA 602
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 697052767 664 TVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIESIKALRKVRR 719
Cdd:PRK10060 603 IVAVAQALNLQVIAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYKRYL 658
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
474-709 |
2.34e-88 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 277.18 E-value: 2.34e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 474 ENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPY-- 551
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRTGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWqa 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 552 ---GELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYS 628
Cdd:smart00052 81 qgpPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 629 SIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPI 708
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
.
gi 697052767 709 E 709
Cdd:smart00052 241 D 241
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
474-705 |
1.74e-75 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 242.99 E-value: 1.74e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 474 ENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL---QP 550
Cdd:pfam00563 1 ARALRRALENGEFVLYYQPIVDLRTGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLaqlQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 551 YGELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSI 630
Cdd:pfam00563 81 GPDIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052767 631 GYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQP 705
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| YjcC |
COG4943 |
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ... |
465-714 |
1.79e-71 |
|
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];
Pssm-ID: 443970 [Multi-domain] Cd Length: 528 Bit Score: 242.13 E-value: 1.79e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 465 SVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRA 544
Cdd:COG4943 264 RLLRRRLSPRRRLRRAIKRREFYVHYQPIVDLKTGRCVGAEALVRWRDPDGSVISPDIFIPLAEQSGLISPLTRQVIEQV 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 545 CEDLQPYG----ELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYvLENPERARMAIANLKALGTAVAL 620
Cdd:COG4943 344 FRDLGDLLaadpDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEITERG-FIDPAKARAVIAALREAGHRIAI 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 621 DDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGF 700
Cdd:COG4943 423 DDFGTGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNLDVVAEGVETEEQADYLRARGVQYGQGW 502
|
250
....*....|....
gi 697052767 701 WFSQPMPIESIKAL 714
Cdd:COG4943 503 LFAKPLPAEEFIAW 516
|
|
| PRK13561 |
PRK13561 |
putative diguanylate cyclase; Provisional |
305-709 |
2.24e-69 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 184143 [Multi-domain] Cd Length: 651 Bit Score: 239.62 E-value: 2.24e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 305 LSHLPNRRALIETLDRVRLRGDTdvKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFAMT 384
Cdd:PRK13561 236 VSDLPNKALLMALLEQVVARKQT--TALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMVLAQISGYDFAII 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 385 IGGDDAEAQATAFAVSVLDFLTTPVQLGERTIHIGASIGIA--SGTLTecnSSELFRRADIAMYHAKMSGKGRITHYDAE 462
Cdd:PRK13561 314 ANGVKEPWHAITLGQQVLTIINERLPIQRIQLRPSCSIGIAmfYGDLT---AEQLYSRAISAAFTARRKGKNQIQFFDPQ 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 463 LNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWpRRPEGPLG-PDTFIAIAETSGLIYKLGQFVL 541
Cdd:PRK13561 391 QMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRSGKLVSAEALLRM-QQPDGSWDlPEGLIDRIESCGLMVTVGHWVL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 542 QRACEDL---QPYG-ELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTA 617
Cdd:PRK13561 470 EESCRLLaawQERGiMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVR 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 618 VALDDFGTGYSSIGYLRRFN---FDTIKIDKS-LAGLVDNDeqaaALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAG 693
Cdd:PRK13561 550 VALDDFGMGYAGLRQLQHMKslpIDVLKIDKMfVDGLPEDD----SMVAAIIMLAQSLNLQVIAEGVETEAQRDWLLKAG 625
|
410
....*....|....*.
gi 697052767 694 CDQLQGFWFSQPMPIE 709
Cdd:PRK13561 626 VGIAQGFLFARALPIE 641
|
|
| PRK11359 |
PRK11359 |
cyclic-di-GMP phosphodiesterase; Provisional |
283-711 |
8.64e-69 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 240.83 E-value: 8.64e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 283 SVGLYKLA--RGESQARLV--ARTDWLSHLPNRRALIETLDRvrLRGDTDVKSVVFIDLDGFKDVNDIYGHSVGDDLIVA 358
Cdd:PRK11359 355 SQHLAALAleQEKSRQHIEqlIQFDPLTGLPNRNNLHNYLDD--LVDKAVSPVVYLIGVDHFQDVIDSLGYAWADQALLE 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 359 IAKTLNERVPPGGMLARMGGDEFAMTIGGDDAEaQATAFAVSVLDFLTTPVQLGERTIHIGASIGIA--SGTltecNSSE 436
Cdd:PRK11359 433 VVNRFREKLKPDQYLCRIEGTQFVLVSLENDVS-NITQIADELRNVVSKPIMIDDKPFPLTLSIGISydVGK----NRDY 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 437 LFRRADIAMYHAKMSGKGRITHYDAELNSVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEG 516
Cdd:PRK11359 508 LLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAETGELYGIEALARWHDPLHG 587
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 517 PLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPYGELK-----LSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLE 591
Cdd:PRK11359 588 HVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNihipaLSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQLTVE 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 592 VTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANAL 671
Cdd:PRK11359 668 ITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSL 747
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 697052767 672 GMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIESI 711
Cdd:PRK11359 748 NLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEI 787
|
|
| PRK11829 |
PRK11829 |
biofilm formation regulator HmsP; Provisional |
306-707 |
3.66e-64 |
|
biofilm formation regulator HmsP; Provisional
Pssm-ID: 183329 [Multi-domain] Cd Length: 660 Bit Score: 225.59 E-value: 3.66e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 306 SHLPNRRALIETLDR-VRLRGDTDVKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFAMT 384
Cdd:PRK11829 238 TELPNRSLFISLLEKeIASSTRTDHFHLLVIGIETLQEVSGAMSEAQHQQLLLTIVQRIEQCIDDSDLLAQLSKTEFAVL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 385 IGGDDAEAQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRITHYDAELN 464
Cdd:PRK11829 318 ARGTRRSFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESMMRNASTAMMAAHHEGRNQIMVFEPHLI 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 465 SVRERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRA 544
Cdd:PRK11829 398 EKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIGAEALLRWCQPDGSYVLPSGFVHFAEEEGMMVPLGNWVLEEA 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 545 CE---DLQPYG-ELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVAL 620
Cdd:PRK11829 478 CRilaDWKARGvSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITETAQIQDLDEALRLLRELQGLGLLIAL 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 621 DDFGTGYSSIGYLRRFN---FDTIKIDKSlagLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQL 697
Cdd:PRK11829 558 DDFGIGYSSLRYLNHLKslpIHMIKLDKS---FVKNLPEDDAIARIISCVSDVLKVRVMAEGVETEEQRQWLLEHGIQCG 634
|
410
....*....|
gi 697052767 698 QGFWFSQPMP 707
Cdd:PRK11829 635 QGFLFSPPLP 644
|
|
| PRK09776 |
PRK09776 |
putative diguanylate cyclase; Provisional |
300-709 |
4.88e-58 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 182070 [Multi-domain] Cd Length: 1092 Bit Score: 213.38 E-value: 4.88e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNR----RALIETLDRVRLRGDTDVksVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLAR 375
Cdd:PRK09776 665 ASHDALTHLANRasfeKQLRRLLQTVNSTHQRHA--LVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDVLAR 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 376 MGGDEFAMTIGgDDAEAQATAFAVSVLDflttpvQLGE-------RTIHIGASIGIASGTLTECNSSELFRRADIAMYHA 448
Cdd:PRK09776 743 LGGDEFGLLLP-DCNVESARFIATRIIS------AINDyhfpwegRVYRVGASAGITLIDANNHQASEVMSQADIACYAA 815
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 449 KMSGKGRITHYDAELNSVR--ERKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVR-WprRPEGPL-GPDTFI 524
Cdd:PRK09776 816 KNAGRGRVTVYEPQQAAAHseHRALSLAEQWRMIKENQLMMLAHGVASPRIPEARNHWLISLRlW--DPEGEIiDEGAFR 893
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 525 AIAETSGLIYKLGQFVLQRAcedLQPYGE------LKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVL 598
Cdd:PRK09776 894 PAAEDPALMHALDRRVIHEF---FRQAAKavaskgLSIALPLSVAGLSSPTLLPFLLEQLENSPLPPRLLHLEITETALL 970
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 599 ENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAE 678
Cdd:PRK09776 971 NHAESASRLVQKLRLAGCRVVLSDFGRGLSSFNYLKAFMADYLKLDGELVANLHGNLMDEMLISIIQGHAQRLGMKTIAG 1050
|
410 420 430
....*....|....*....|....*....|.
gi 697052767 679 GVETEKQMKLLRLAGCDQLQGFWFSQPMPIE 709
Cdd:PRK09776 1051 PVELPLVLDTLSGIGVDLAYGYAIARPQPLD 1081
|
|
| CHASE4 |
COG3322 |
Extracellular (periplasmic) sensor domain CHASE (specificity unknown) [Signal transduction ... |
14-716 |
3.03e-53 |
|
Extracellular (periplasmic) sensor domain CHASE (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 442551 [Multi-domain] Cd Length: 724 Bit Score: 196.32 E-value: 3.03e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 14 RTLFALVFMAGIGLIISIVALLYLSLHLI----STKTNEIDEHRTALSVQGSIQTSVNRVSSLVLDNAVWDDAVREAYRP 89
Cdd:COG3322 1 MSLRRKTLLAILLLLLLLLALLYLVSRLIllssFSELEEQAAERDVERVLNALDAELDQLARLVADWAVWDDTYEFVQDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 90 tlDTDWLYNTWGTGFKINNLYDGTFVLDEHFNVLWGsfQSRPFNEKNLDFFGKGLKALIDQHGREL--AGEKNIYAGISQ 167
Cdd:COG3322 81 --DPEWIESNLGDWTFENLGLDLVLVLDPDGRLVYS--KGYDLEDGELVPLPEALAPLLARARALLrhASPDSSVSGLLR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 168 TRNGVAFVGIGLIRPMVGSlqihDGTRRYLVITRHLNARILSDLGGTFQIDnLHFTPGKINDR---------------SM 232
Cdd:COG3322 157 LDGGPALVAARPILPSDGP----GPPRGTLVFGRYLDEAFLARLAERTGLD-LTLSPADPPAPpdqvveplsddtiagYV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 233 PLHSAAGELVGYLNWQARLPGAQAARAassdirqIVVLVSGLILLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRR 312
Cdd:COG3322 232 PLRDIDGQPVLLLRWTPPRPIYQQGRA-------LLRYLLPALLLLGLLLALLALLLLRLVLLLLLLLLRLVLSRLLLLL 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 313 ALIETLDRVRLRGDTDVKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFAMTIGGDDAEA 392
Cdd:COG3322 305 LRLLLLELLRALELLLLLLRRLLLLLLLLRLLLLLLDLLAALNLLLLLRALAERLVALALLALLLLGLLGLLAALRRLGL 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 393 QATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRITHYDAELNSVRERKLA 472
Cdd:COG3322 385 LAILALAEEAARLLLLALAIAGELLIGIEVLLALGLELAGSAIALARAAAALALLLAAAAAARLAARAASGLLRDLLEAD 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 473 IENQIRSGLERDEFEVWYQPIVDARSQT-MSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDLQPY 551
Cdd:COG3322 465 ELEDRLRRALLAEAAALLLLALLALELLlALGDAALEILLAILLLGLVLEAQLAELERLLLLGEAGGELLEEIALLAALL 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 552 GELKLSVNISPAQFRDPAFEEKVASVLESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIG 631
Cdd:COG3322 545 AGLLLAVLLSLLLRLLLLIDALVALAEAAAGLLEALLEEEVELRRALLEAEELLLIALALLSLGLALALDDGGRGLAGLL 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 632 YLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIESI 711
Cdd:COG3322 625 LLFRLSGIGLLLLRRLLGDDLLGLLAALIDLILALAGSLLLLTLAAAAEATAVVLVAELLEGALLLQALALISLLELLLL 704
|
....*
gi 697052767 712 KALRK 716
Cdd:COG3322 705 LLLLE 709
|
|
| PRK10551 |
PRK10551 |
cyclic di-GMP phosphodiesterase; |
469-720 |
2.09e-49 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 182541 [Multi-domain] Cd Length: 518 Bit Score: 181.34 E-value: 2.09e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 469 RKLAIENQIRSGLERDEFEVWYQPIVDARSQTMSSVEALVRWPRRPEGPLGPDTFIAIAETSGLIYKLGQFVLQRACEDL 548
Cdd:PRK10551 260 LRMRPGKEILTGIKRGQFYVEYQPVVDTQTLRVTGLEALLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 549 Q------PYGeLKLSVNISPAQFRDPAFEEKVASVLEStrFPANRLQ--LEVTESYVLENPERARMaIANLKALGTAVAL 620
Cdd:PRK10551 340 AelqkvlPVG-AKLGINISPAHLHSDSFKADVQRLLAS--LPADHFQivLEITERDMVQEEEATKL-FAWLHSQGIEIAI 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 621 DDFGTGYSSIGYLRRFNFDTIKIDKslaGLVDN--DEQAAALVSGTVRI-ANALGMAVVAEGVETEKQMKLLRLAGCDQL 697
Cdd:PRK10551 416 DDFGTGHSALIYLERFTLDYLKIDR---GFIQAigTETVTSPVLDAVLTlAKRLNMLTVAEGVETPEQARWLRERGVNFL 492
|
250 260
....*....|....*....|...
gi 697052767 698 QGFWFSQPMPIESIKALRKVRRC 720
Cdd:PRK10551 493 QGYWISRPLPLEDFVRWLKEPYT 515
|
|
| GGDEF |
cd01949 |
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: ... |
301-456 |
4.59e-47 |
|
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.
Pssm-ID: 143635 [Multi-domain] Cd Length: 158 Bit Score: 163.88 E-value: 4.59e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 301 RTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGG 378
Cdd:cd01949 1 YTDPLTGLPNRRAFEERLERLLARARRSGRplALLLIDIDHFKQINDTYGHAAGDEVLKEVAERLRSSLRESDLVARLGG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052767 379 DEFAMTIGGDDAEaQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRI 456
Cdd:cd01949 81 DEFAILLPGTDLE-EAEALAERLREAIEEPFFIDGQEIRVTASIGIATYPEDGEDAEELLRRADEALYRAKRSGRNRV 157
|
|
| GGDEF |
COG2199 |
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants ... |
195-459 |
1.40e-46 |
|
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms];
Pssm-ID: 441801 [Multi-domain] Cd Length: 275 Bit Score: 166.69 E-value: 1.40e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 195 RYLVITRHLNARILSDLGGTFQIDNLHFTPGKINDRSMPLHSAAGELVGYLNWQARLPGAQAARAASSDIRQIVVLVSGL 274
Cdd:COG2199 9 LALLLLLLLLLLSLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLLLLALGLLLLALLLLSLVLELLLLLL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 275 ILLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYGHSVG 352
Cdd:COG2199 89 ALLLLLLALEDITELRRLEERLRRLATHDPLTGLPNRRAFEERLERELARARREGRplALLLIDLDHFKRINDTYGHAAG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 353 DDLIVAIAKTLNERVPPGGMLARMGGDEFAMTIGGDDAEaQATAFAVSVLDFL-TTPVQLGERTIHIGASIGIASGTLTE 431
Cdd:COG2199 169 DEVLKEVARRLRASLRESDLVARLGGDEFAVLLPGTDLE-EAEALAERLREALeQLPFELEGKELRVTVSIGVALYPEDG 247
|
250 260
....*....|....*....|....*...
gi 697052767 432 CNSSELFRRADIAMYHAKMSGKGRITHY 459
Cdd:COG2199 248 DSAEELLRRADLALYRAKRAGRNRVVVY 275
|
|
| GGDEF |
smart00267 |
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria. |
300-459 |
3.29e-39 |
|
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria.
Pssm-ID: 128563 [Multi-domain] Cd Length: 163 Bit Score: 142.39 E-value: 3.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNRRALIETLDRV--RLRGDTDVKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMG 377
Cdd:smart00267 3 AFRDPLTGLPNRRYFEEELEQElqRAQRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLRPGDLLARLG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 378 GDEFAMTIGGDDAEaQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGRIT 457
Cdd:smart00267 83 GDEFALLLPETSLE-EAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRNQVA 161
|
..
gi 697052767 458 HY 459
Cdd:smart00267 162 VY 163
|
|
| GGDEF |
pfam00990 |
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of ... |
300-455 |
6.32e-37 |
|
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. It has been shown to be homologous to the adenylyl cyclase catalytic domain and has diguanylate cyclase activity. This observation correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. In the WspR protein of Pseudomonas aeruginosa, the GGDEF domain acts as a diguanylate cyclase, PDB:3bre, when the whole molecule appears to form a tetramer consisting of two symmetrically-related dimers representing a biological unit. The active site is the GGD/EF motif, buried in the structure, and the cyclic dimeric guanosine monophosphate (c-di-GMP) bind to the inhibitory-motif RxxD on the surface. The enzyme thus catalyzes the cyclization of two guanosine triphosphate (GTP) molecules to one c-di-GMP molecule.
Pssm-ID: 425976 [Multi-domain] Cd Length: 160 Bit Score: 135.84 E-value: 6.32e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMG 377
Cdd:pfam00990 1 AAHDPLTGLPNRRYFEEQLEQELQRALREGSpvAVLLIDLDNFKRINDTYGHSVGDEVLQEVAQRLSSSLRRSDLVARLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 378 GDEFAMTIGG--DDAEAQATAFAVSVLDFLTTPVQLGERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKGR 455
Cdd:pfam00990 81 GDEFAILLPEtsLEGAQELAERIRRLLAKLKIPHTVSGLPLYVTISIGIAAYPNDGEDPEDLLKRADTALYQAKQAGRNR 160
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
300-456 |
2.70e-27 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 108.58 E-value: 2.70e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMG 377
Cdd:TIGR00254 2 AVRDPLTGLYNRRYLEEMLDSELKRARRFQRsfSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSSVRGSDVVGRYG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 378 GDEFAMTIGGDDAEaQATAFAVSV---LDFLTTPVQLGErTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKMSGKG 454
Cdd:TIGR00254 82 GEEFVVILPGTPLE-DALSKAERLrdaINSKPIEVAGSE-TLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRN 159
|
..
gi 697052767 455 RI 456
Cdd:TIGR00254 160 RV 161
|
|
| PRK09894 |
PRK09894 |
diguanylate cyclase; Provisional |
303-460 |
1.29e-20 |
|
diguanylate cyclase; Provisional
Pssm-ID: 182133 [Multi-domain] Cd Length: 296 Bit Score: 92.82 E-value: 1.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 303 DWLSHLPNRRALIETLDRVRLRGDTDVKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFA 382
Cdd:PRK09894 132 DVLTGLPGRRVLDESFDHQLRNREPQNLYLALLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFI 211
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052767 383 MTIgGDDAEAQATAFAVSV-LDFLTTPVQLGERTIHIGASIGIASGTLTEcNSSELFRRADIAMYHAKMSGKGRITHYD 460
Cdd:PRK09894 212 ICL-KAATDEEACRAGERIrQLIANHAITHSDGRINITATFGVSRAFPEE-TLDVVIGRADRAMYEGKQTGRNRVMFID 288
|
|
| pleD |
PRK09581 |
response regulator PleD; Reviewed |
300-456 |
1.18e-19 |
|
response regulator PleD; Reviewed
Pssm-ID: 236577 [Multi-domain] Cd Length: 457 Bit Score: 92.66 E-value: 1.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 300 ARTDWLSHLPNRRAL---IETL-DRVRLRGDTdvKSVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVPPGGMLAR 375
Cdd:PRK09581 292 AVTDGLTGLHNRRYFdmhLKNLiERANERGKP--LSLMMIDIDHFKKVNDTYGHDAGDEVLREFAKRLRNNIRGTDLIAR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 376 MGGDEFAMT---IGGDDAEAQATAFAVSVldfLTTPVQL--GERTIHIGASIGIASGTLTECNSSELFRRADIAMYHAKM 450
Cdd:PRK09581 370 YGGEEFVVVmpdTDIEDAIAVAERIRRKI---AEEPFIIsdGKERLNVTVSIGVAELRPSGDTIEALIKRADKALYEAKN 446
|
....*.
gi 697052767 451 SGKGRI 456
Cdd:PRK09581 447 TGRNRV 452
|
|
| adrA |
PRK10245 |
diguanylate cyclase AdrA; Provisional |
276-455 |
1.35e-18 |
|
diguanylate cyclase AdrA; Provisional
Pssm-ID: 182329 [Multi-domain] Cd Length: 366 Bit Score: 88.35 E-value: 1.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 276 LLFILVSSVGLYKLARGESQARLVARTDWLSHLPNRRALiETLDRVR----LRGDTDVkSVVFIDLDGFKDVNDIYGHSV 351
Cdd:PRK10245 181 LLFAWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHW-ETLLRNEfdncRRHHRDA-TLLIIDIDHFKSINDTWGHDV 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 352 GDDLIVAIAKTLNERVPPGGMLARMGGDEFAMTIGGDDAEAQATAFA-----VSVLDFLTTPvqlgERTIHIgaSIGIAS 426
Cdd:PRK10245 259 GDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMSrvhegLNTLRLPNAP----QVTLRI--SVGVAP 332
|
170 180
....*....|....*....|....*....
gi 697052767 427 GTLTECNSSELFRRADIAMYHAKMSGKGR 455
Cdd:PRK10245 333 LNPQMSHYREWLKSADLALYKAKNAGRNR 361
|
|
| PRK15426 |
PRK15426 |
cellulose biosynthesis regulator YedQ; |
273-456 |
1.31e-15 |
|
cellulose biosynthesis regulator YedQ;
Pssm-ID: 237964 [Multi-domain] Cd Length: 570 Bit Score: 80.44 E-value: 1.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 273 GLILLFILVSSVGLYK--LARGESqARLVARTDWLSHLPNRRALIETLDRVRLRGDTDVK--SVVFIDLDGFKDVNDIYG 348
Cdd:PRK15426 370 TAMLLISWYVIRRMVSnmFVLQSS-LQWQAWHDPLTRLYNRGALFEKARALAKRCQRDQQpfSVIQLDLDHFKSINDRFG 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 349 HSVGDDLIVAIAKTLNERVPPGGMLARMGGDEFAMTI-GGDDAEAQATA----FAVSVLDFLTTPvqlgERTIHIGASIG 423
Cdd:PRK15426 449 HQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVVLpGASLAEAAQVAerirLRINEKEILVAK----STTIRISASLG 524
|
170 180 190
....*....|....*....|....*....|....
gi 697052767 424 IASGTLTECNSSE-LFRRADIAMYHAKMSGKGRI 456
Cdd:PRK15426 525 VSSAEEDGDYDFEqLQSLADRRLYLAKQAGRNRV 558
|
|
| PRK11059 |
PRK11059 |
regulatory protein CsrD; Provisional |
332-708 |
2.31e-14 |
|
regulatory protein CsrD; Provisional
Pssm-ID: 236833 [Multi-domain] Cd Length: 640 Bit Score: 76.82 E-value: 2.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 332 VVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERVP--PGGMLARMGGDEFAMT---IGGDDAEAQAtAFAVSVLDFLT 406
Cdd:PRK11059 262 VMLIRLPDFDLLQEEWGESQVEELLFELINLLSTFVMryPGALLARYSRSDFAVLlphRSLKEADSLA-SQLLKAVDALP 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 407 -TPVQLGERTIHIGASiGIASGTLTEcnssELFRRADIAMYHAKMSGKGRITHYDAE------LNSVRERKLaIENQirs 479
Cdd:PRK11059 341 pPKMLDRDDFLHIGIC-AYRSGQSTE----QVMEEAEMALRSAQLQGGNGWFVYDKAqlpekgRGSVRWRTL-LEQT--- 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 480 gLERDEFEVWYQPIVDARSQTMSSvEALVRWpRRPEGPLGPDT-FIAIAETSGLIYKLGQFVLQRACEDLQPYGELKLSV 558
Cdd:PRK11059 412 -LVRGGPRLYQQPAVTRDGKVHHR-ELFCRI-RDGQGELLSAElFMPMVQQLGLSEQYDRQVIERVLPLLRYWPEENLSI 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 559 NISPAQFRDPAFEEKVASVL-ESTRFPANRLQLEVTESYVLENPERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFN 637
Cdd:PRK11059 489 NLSVDSLLSRAFQRWLRDTLlQCPRSQRKRLIFELAEADVCQHISRLRPVLRMLRGLGCRLAVDQAGLTVVSTSYIKELN 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 638 FDTIKIDKSlagLVDNDEQaaalvsgtvRIANAL------------GMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQP 705
Cdd:PRK11059 569 VELIKLHPS---LVRNIHK---------RTENQLfvrslvgacagtETQVFATGVESREEWQTLQELGVSGGQGDFFAES 636
|
...
gi 697052767 706 MPI 708
Cdd:PRK11059 637 QPL 639
|
|
| PRK09966 |
PRK09966 |
diguanylate cyclase DgcN; |
293-449 |
6.66e-13 |
|
diguanylate cyclase DgcN;
Pssm-ID: 182171 [Multi-domain] Cd Length: 407 Bit Score: 71.19 E-value: 6.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 293 ESQARLVART---------DWLSHLPNRRALIETLDRvrLRGDTDVKS---VVFIDLDGFKDVNDIYGHSVGDDLIVAIA 360
Cdd:PRK09966 232 EWQLRLQAKNaqllrtalhDPLTGLANRAAFRSGINT--LMNNSDARKtsaLLFLDGDNFKYINDTWGHATGDRVLIEIA 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 361 KTLNERVPPGGMLARMGGDEFAMTIGGDDAEAQATAFAVSVLDFLTTPVQL--GERtIHIGASIGIASgTLTECNSSELF 438
Cdd:PRK09966 310 KRLAEFGGLRHKAYRLGGDEFAMVLYDVQSESEVQQICSALTQIFNLPFDLhnGHQ-TTMTLSIGYAM-TIEHASAEKLQ 387
|
170
....*....|.
gi 697052767 439 RRADIAMYHAK 449
Cdd:PRK09966 388 ELADHNMYQAK 398
|
|
| YuxH |
COG3434 |
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ... |
558-710 |
1.10e-11 |
|
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];
Pssm-ID: 442660 [Multi-domain] Cd Length: 407 Bit Score: 67.13 E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 558 VNISPAQFRDPAFEEkvasvlestrFPANRLQLEVTESYVLEnpERARMAIANLKALGTAVALDDFGTGYSSIGYLRRFN 637
Cdd:COG3434 66 INFTEELLLSDLPEL----------LPPERVVLEILEDVEPD--EELLEALKELKEKGYRIALDDFVLDPEWDPLLPLAD 133
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052767 638 FdtIKIDksLAGLvdNDEQAAALVsgtvRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQGFWFSQPMPIES 710
Cdd:COG3434 134 I--IKID--VLAL--DLEELAELV----ARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEILKG 196
|
|
| Nucleotidyl_cyc_III |
cd07556 |
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse ... |
331-427 |
2.50e-08 |
|
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse group of nucleotidyl cyclases (NC's) containing prokaryotic and eukaryotic proteins. They can be divided into two major groups; the mononucleotidyl cyclases (MNC's) and the diguanylate cyclases (DGC's). The MNC's, which include the adenylate cyclases (AC's) and the guanylate cyclases (GC's), have a conserved cyclase homology domain (CHD), while the DGC's have a conserved GGDEF domain, named after a conserved motif within this subgroup. Their products, cyclic guanylyl and adenylyl nucleotides, are second messengers that play important roles in eukaryotic signal transduction and prokaryotic sensory pathways.
Pssm-ID: 143637 [Multi-domain] Cd Length: 133 Bit Score: 53.13 E-value: 2.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 331 SVVFIDLDGFKDVNDIYGHSVGDDLIVAIAKTLNERV-PPGGMLARMGGDEFAMTIGGDDAeAQATAFAVSVLD-FLTTP 408
Cdd:cd07556 3 TILFADIVGFTSLADALGPDEGDELLNELAGRFDSLIrRSGDLKIKTIGDEFMVVSGLDHP-AAAVAFAEDMREaVSALN 81
|
90
....*....|....*....
gi 697052767 409 VQLGErtiHIGASIGIASG 427
Cdd:cd07556 82 QSEGN---PVRVRIGIHTG 97
|
|
| PRK11596 |
PRK11596 |
cyclic-di-GMP phosphodiesterase; Provisional |
620-715 |
1.58e-07 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183222 [Multi-domain] Cd Length: 255 Bit Score: 53.08 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 620 LDDFGTGYSSIGYLRRFNFDTIKIDKSLAGLVDNDEQAAALVSGTVRIANALGMAVVAEGVETEKQMKLLRLAGCDQLQG 699
Cdd:PRK11596 157 LDDFGTGMANFSALSEVRYDYIKVARELFIMLRQSEEGRNLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQRSPAFAAQG 236
|
90
....*....|....*.
gi 697052767 700 FWFSQPMPIESIKALR 715
Cdd:PRK11596 237 YFLSRPAPFETLETLP 252
|
|
| CHASE4 |
pfam05228 |
CHASE4 domain; CHASE4. This is an extracellular sensory domain, which is present in various ... |
61-212 |
2.05e-06 |
|
CHASE4 domain; CHASE4. This is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in prokaryotes. Specifically, CHASE4 domains are found in histidine kinases in Archaea and in predicted diguanylate cyclases/phosphodiesterases in Bacteria. Environmental factors that are recognized by CHASE4 domains are not known at this time.
Pssm-ID: 428380 Cd Length: 139 Bit Score: 47.71 E-value: 2.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052767 61 SIQTSVNRVSSLVLDNAVWDDAVREAYRPtlDTDWLYNTWGTGFKINNLYDGTFVLDEHFNVLWgsfqsrpfNEKNLDFF 140
Cdd:pfam05228 1 ALEQELDSLDRLLRDWAVWDDTYDFVQDG--NPDYIESNLGPETFENLGLDLILFVDADGKLVY--------DLENGKPD 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052767 141 GKGLKALIDQHGRelagekniyAGISQTRNGVAFVGIGLIRPMVGSLQIHDgtrrYLVITRHLNARILSDLG 212
Cdd:pfam05228 71 SPLLSRSSPDSGL---------SGIVLLGGGPALVAARPILTSDGSGPPRG----TLVMGRYLDEAFLDRLS 129
|
|
| PleD |
COG3706 |
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate ... |
372-449 |
2.32e-04 |
|
Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain [Signal transduction mechanisms, Transcription];
Pssm-ID: 442920 [Multi-domain] Cd Length: 179 Bit Score: 42.59 E-value: 2.32e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052767 372 MLARMGGDEFAMTIGGDDAEaQATAFAVSVLDFLTTPvqlgeRTIHIGASIGIASGTltecnsseLFRRADiAMYHAK 449
Cdd:COG3706 117 LVARYGGEEFAILLPGTDLE-GALAVAERIREAVAEL-----PSLRVTVSIGVAGDS--------LLKRAD-ALYQAR 179
|
|
| |
