NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|697052363|ref|WP_033144969|]
View 

MULTISPECIES: 6-phosphogluconolactonase [Enterobacter]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 11485154)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


:

Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.83  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   2 KQTVYTASPESQQIHVWRLNTEGTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRPEFRVLAYRISpDDGALTYTAEAPLP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  82 GSPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVEGLEGCHSANISPDNRTLWVPALKQDRICLFTLSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 161 HLVAQNPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSDTRWAADIHITPNG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 241 RHLYACDRTSSLITVFSISEDGSVLAIEGFQPTETQPRGFNIDHSGKYLIAAGQKSHHIALYEIKGEQGLLEEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 697052363 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.83  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   2 KQTVYTASPESQQIHVWRLNTEGTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRPEFRVLAYRISpDDGALTYTAEAPLP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  82 GSPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVEGLEGCHSANISPDNRTLWVPALKQDRICLFTLSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 161 HLVAQNPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSDTRWAADIHITPNG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 241 RHLYACDRTSSLITVFSISEDGSVLAIEGFQPTETQPRGFNIDHSGKYLIAAGQKSHHIALYEIKGEQGLLEEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 697052363 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
6-328 1.48e-129

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 373.47  E-value: 1.48e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   6 YTaSPESQQIHVWRLNTE-GTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRP-EFRVLAYRISPDDGALTYTAEAPLPG- 82
Cdd:COG2706   15 YT-SGESEGIYVFRLDTAtGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLNTVSSGGa 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  83 SPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVE-----------GLEGCHSANISPDNRTLWVPALKQDR 150
Cdd:COG2706   94 SPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYVPDLGTDR 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 151 ICLFTLS-DDGHLVAqnPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSDTR 229
Cdd:COG2706  174 IYVYRLDpATGKLPE--PPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLPEDFTGEN 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 230 WAADIHITPNGRHLYACDRTSSLITVFSISEDGSVLAIEGFQPTE-TQPRGFNIDHSGKYLIAAGQKSHHIALYEIKGEQ 308
Cdd:COG2706  252 WAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITVFRIDADT 331

                        330       340
                 ....*....|....*....|
gi 697052363 309 GLLEEKGRYAVGQGPMWVVV 328
Cdd:COG2706  332 GKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 6-324 9.27e-121

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 350.75  E-value: 9.27e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363    6 YTaSPESQQIHVWRLNTE-GTLTLVQVVDVPGQVQPMVISPDKRFLYVGVR--PEFRVLAYRISPDDGALTYTAEAP-LP 81
Cdd:pfam10282   7 YT-KGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQVPtGG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   82 GSPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVEGlEG------------CHSANISPDNRTLWVPALKQ 148
Cdd:pfam10282  86 ASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVQH-EGsgppperqesphPHSVDLTPDGKFLVVPDLGT 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  149 DRICLFTLSDD-GHLVAqnPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSD 227
Cdd:pfam10282 165 DRVRVYKLDAGgGKLTP--PASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPEGFTG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  228 TRWAADIHITPNGRHLYACDRTSSLITVFSISEDGSVLAIEGFQPTETQ-PRGFNIDHSGKYLIAAGQKSHHIALYEIKG 306
Cdd:pfam10282 243 TNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVFRRDP 322

                         330
                  ....*....|....*...
gi 697052363  307 EQGLLEEKGRYAVGQGPM 324
Cdd:pfam10282 323 ETGKLTLLGKDIEVPEPV 340
 
Name Accession Description Interval E-value
PRK11028 PRK11028
6-phosphogluconolactonase; Provisional
 2-331 0e+00

6-phosphogluconolactonase; Provisional


Pssm-ID: 182912 [Multi-domain]  Cd Length: 330  Bit Score: 672.83  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   2 KQTVYTASPESQQIHVWRLNTEGTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRPEFRVLAYRISpDDGALTYTAEAPLP 81
Cdd:PRK11028   1 KQIVYIASPESQQIHVWNLNHEGALTLLQVVDVPGQVQPMVISPDKRHLYVGVRPEFRVLSYRIA-DDGALTFAAESPLP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  82 GSPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVEGLEGCHSANISPDNRTLWVPALKQDRICLFTLSDDG 160
Cdd:PRK11028  80 GSPTHISTDHQGRFLFSASYNANCVSVSPLdKDGIPVAPIQIIEGLEGCHSANIDPDNRTLWVPCLKEDRIRLFTLSDDG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 161 HLVAQNPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSDTRWAADIHITPNG 240
Cdd:PRK11028 160 HLVAQEPAEVTTVEGAGPRHMVFHPNQQYAYCVNELNSSVDVWQLKDPHGEIECVQTLDMMPADFSDTRWAADIHITPDG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 241 RHLYACDRTSSLITVFSISEDGSVLAIEGFQPTETQPRGFNIDHSGKYLIAAGQKSHHIALYEIKGEQGLLEEKGRYAVG 320
Cdd:PRK11028 240 RHLYACDRTASLISVFSVSEDGSVLSFEGHQPTETQPRGFNIDHSGKYLIAAGQKSHHISVYEIDGETGLLTELGRYAVG 319

                        330
                 ....*....|.
gi 697052363 321 QGPMWVVVNAH 331
Cdd:PRK11028 320 QGPMWVSVLAL 330
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
6-328 1.48e-129

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 373.47  E-value: 1.48e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   6 YTaSPESQQIHVWRLNTE-GTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRP-EFRVLAYRISPDDGALTYTAEAPLPG- 82
Cdd:COG2706   15 YT-SGESEGIYVFRLDTAtGELTLLGLVAALGNPSFLALSPDGRFLYAVNEVdDGGVSAFRIDPADGTLTLLNTVSSGGa 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  83 SPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVE-----------GLEGCHSANISPDNRTLWVPALKQDR 150
Cdd:COG2706   94 SPCHLSVDPDGRFLFVANYGGGSVSVFPIdADGSLGEPVQVIQhegsgpnperqEGPHAHSVVFDPDGRFLYVPDLGTDR 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 151 ICLFTLS-DDGHLVAqnPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSDTR 229
Cdd:COG2706  174 IYVYRLDpATGKLPE--PPEVSLPPGSGPRHLAFHPNGRFAYVINELDSTVSVYAYDAATGTLTLIQTVSTLPEDFTGEN 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 230 WAADIHITPNGRHLYACDRTSSLITVFSISEDGSVLAIEGFQPTE-TQPRGFNIDHSGKYLIAAGQKSHHIALYEIKGEQ 308
Cdd:COG2706  252 WAADIHISPDGRFLYVSNRGHNSIAVFAIDADGGKLTLVGHVPTGgKWPRDFAIDPDGRFLLVANQKSDNITVFRIDADT 331

                        330       340
                 ....*....|....*....|
gi 697052363 309 GLLEEKGRYAVGQGPMWVVV 328
Cdd:COG2706  332 GKLTPTGRSVPVPSPVCVAF 351
Lactonase pfam10282
Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases ...
 6-324 9.27e-121

Lactonase, 7-bladed beta-propeller; This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyse 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.


Pssm-ID: 431196 [Multi-domain]  Cd Length: 340  Bit Score: 350.75  E-value: 9.27e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363    6 YTaSPESQQIHVWRLNTE-GTLTLVQVVDVPGQVQPMVISPDKRFLYVGVR--PEFRVLAYRISPDDGALTYTAEAP-LP 81
Cdd:pfam10282   7 YT-KGDSKGIYVLTLDTEtGALTLLGLVAEVGNPSYLALSPDGRTLYAVNEegDQGGVAAFRIDPDSGALTLLNQVPtGG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   82 GSPTHISTDRKGNFVFSGSYNAGCVSVTRL-EDGIPVETVDVVEGlEG------------CHSANISPDNRTLWVPALKQ 148
Cdd:pfam10282  86 ASPCHLSVDPDGRFLFVANYHGGSVSVFPLdADGSLGELSQVVQH-EGsgppperqesphPHSVDLTPDGKFLVVPDLGT 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  149 DRICLFTLSDD-GHLVAqnPAEVTTVEGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDPNGQIECVQTLDMMPSDFSD 227
Cdd:pfam10282 165 DRVRVYKLDAGgGKLTP--PASVQTPPGSGPRHLAFHPNGKYAYVVNELSSTVTVFEYDPATGTFEELQTVSTLPEGFTG 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  228 TRWAADIHITPNGRHLYACDRTSSLITVFSISEDGSVLAIEGFQPTETQ-PRGFNIDHSGKYLIAAGQKSHHIALYEIKG 306
Cdd:pfam10282 243 TNGAAAIRVSPDGKFLYVSNRGHDSIAVFAVDEAGGTLTLVERVSTEGDfPRDFNIDPDGKFLVVANQDSDNVTVFRRDP 322

                         330
                  ....*....|....*...
gi 697052363  307 EQGLLEEKGRYAVGQGPM 324
Cdd:pfam10282 323 ETGKLTLLGKDIEVPEPV 340
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
4-201 6.12e-10

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 58.55  E-value: 6.12e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   4 TVYTASPESQQIHVWRLNTEGTLTLVQVVDVPGQVQPMVISPDKRFLYVGVRPEFRVlaYRISPDDGALTytAEAPLPGS 83
Cdd:COG3391   36 LLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRV--SVIDLATGKVV--ATIPVGGG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  84 PTHISTDRKGNFVFSGSYNAGCVSVTRLEDGIPVETVDVVEGLEGCHsanISPDNRTLWVPALKQDRICLFTLSDDghlv 163
Cdd:COG3391  112 PRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPHGIA---VDPDGKRLYVANSGSNTVSVIVSVID---- 184

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 697052363 164 AQNPAEVTTVE-GAGPRHMVFHPNQQYAYVVNELNSSVD 201
Cdd:COG3391  185 TATGKVVATIPvGGGPVGVAVSPDGRRLYVANRGSNTSN 223
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
136-298 1.77e-09

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 57.40  E-value: 1.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 136 PDNRTLWVPALKQDRICLFTLsDDGHLVAQNPAevttveGAGPRHMVFHPNQQYAYVVNELNSSVDVWELKDpnGQIecV 215
Cdd:COG3391   77 ADGRRLYVANSGSGRVSVIDL-ATGKVVATIPV------GGGPRGLAVDPDGGRLYVADSGNGRVSVIDTAT--GKV--V 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 216 QTLDMmpsdfsdTRWAADIHITPNGRHLYACDRTSSLITVFsISE-DGSVLAIEGFQPTETQPRGFNIDHSGKYLIAAGQ 294
Cdd:COG3391  146 ATIPV-------GAGPHGIAVDPDGKRLYVANSGSNTVSVI-VSViDTATGKVVATIPVGGGPVGVAVSPDGRRLYVANR 217


                 ....
gi 697052363 295 KSHH 298
Cdd:COG3391  218 GSNT 221
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 16-145 6.40e-09

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 56.05  E-value: 6.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  16 HVWRLNTEGTLTLVqvvdVPGQVQP--MVISPDKRFLYVGVRPEFRVLAYRISpDDGALT----YTAEAPLPGSPTHIST 89
Cdd:COG3386  119 ALYRVDPDGSLRVL----ADGLTFPngIAFSPDGRTLYVADTGAGRIYRFDLD-ADGTLGnrrvFADLPDGPGGPDGLAV 193

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052363  90 DRKGNfVFSGSYNAGCVSVtRLEDGIPVETVDVVEGlegcHSANIS---PDNRTLWVPA 145
Cdd:COG3386  194 DADGN-LWVALWGGGGVVR-FDPDGELLGRIELPER----RPTNVAfggPDLRTLYVTT 246
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
113-330 3.67e-08

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 53.54  E-value: 3.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 113 DGIPVETVDVVEGLEGCHSANISPDNRTLWVPALKQDRIclftLSDDGHLVAQNPAEVTTVEGAGPRHMVFHPNQQYAYV 192
Cdd:COG3391    9 VAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGA----AVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 193 VNELNSSVDVWELKdpNGQIecVQTLDMMPSdfsdtrwAADIHITPNGRHLYACDRTSSLITVFsiseDGSVLAIEGFQP 272
Cdd:COG3391   85 ANSGSGRVSVIDLA--TGKV--VATIPVGGG-------PRGLAVDPDGGRLYVADSGNGRVSVI----DTATGKVVATIP 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 273 TETQPRGFNIDHSGKYLIAAGQKSHHIA--LYEIKGEQGllEEKGRYAVGQGPMWVVVNA 330
Cdd:COG3391  150 VGAGPHGIAVDPDGKRLYVANSGSNTVSviVSVIDTATG--KVVATIPVGGGPVGVAVSP 207
WD40 COG2319
WD40 repeat [General function prediction only];
3-266 1.15e-06

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 49.91  E-value: 1.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   3 QTVYTASpESQQIHVWRLNTeGTLtLVQVVDVPGQVQPMVISPDKRFLYVGVRPEfRVLAYRIspDDGALTYTAEAPlPG 82
Cdd:COG2319  133 KTLASGS-ADGTVRLWDLAT-GKL-LRTLTGHSGAVTSVAFSPDGKLLASGSDDG-TVRLWDL--ATGKLLRTLTGH-TG 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  83 SPTHISTDRKGNFVFSGSYNaGCVSVTRLEDGIPVETVDVVEGleGCHSANISPDNRTlwvpalkqdricLFTLSDDGHL 162
Cdd:COG2319  206 AVRSVAFSPDGKLLASGSAD-GTVRLWDLATGKLLRTLTGHSG--SVRSVAFSPDGRL------------LASGSADGTV 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363 163 V---AQNPAEVTTVEG--AGPRHMVFHPNQQYAYVVNElNSSVDVWELKDPngqiECVQTLDmmpsdfSDTRWAADIHIT 237
Cdd:COG2319  271 RlwdLATGELLRTLTGhsGGVNSVAFSPDGKLLASGSD-DGTVRLWDLATG----KLLRTLT------GHTGAVRSVAFS 339

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 697052363 238 PNGRHLYAC--DRT------------------SSLITVFSISEDGSVLA 266
Cdd:COG2319  340 PDGKTLASGsdDGTvrlwdlatgellrtltghTGAVTSVAFSPDGRTLA 388
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 3-162 1.22e-05

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 46.04  E-value: 1.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   3 QTVYTASPESQQIHVWRLNTeGTLTLVQvvDVPGQVQPMVISPDKRfLYVgVRPEFRVlaYRISPDDGALT-YTAEAPLP 81
Cdd:COG3386   19 GRLYWVDIPGGRIHRYDPDG-GAVEVFA--EPSGRPNGLAFDPDGR-LLV-ADHGRGL--VRFDPADGEVTvLADEYGKP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  82 G-SPTHISTDRKGNFVFS--GSYNAGCvSVTRLE-DGipveTVDVVegLEGCHSAN---ISPDNRTLWVPALKQDRICLF 154
Cdd:COG3386   92 LnRPNDGVVDPDGRLYFTdmGEYLPTG-ALYRVDpDG----SLRVL--ADGLTFPNgiaFSPDGRTLYVADTGAGRIYRF 164


                 ....*...
gi 697052363 155 TLSDDGHL 162
Cdd:COG3386  165 DLDADGTL 172
SGL pfam08450
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ...
 17-108 3.30e-03

SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.


Pssm-ID: 462480 [Multi-domain]  Cd Length: 246  Bit Score: 38.40  E-value: 3.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363   17 VWRLNTEGTLTLVqvvdVPGQVQP--MVISPDKRFLYVGVRPEFRVLAYRISPDDGALT-----YTAEaPLPGSPTHIST 89
Cdd:pfam08450 117 LYRLDPDGKLTRV----LDGLTISngLAWSPDGRTLYFADSPARKIWAYDYDLDGGLISnrrvfADFK-PGLGRPDGMAV 191

                          90
                  ....*....|....*....
gi 697052363   90 DRKGNfVFSGSYNAGCVSV 108
Cdd:pfam08450 192 DAEGN-VWVARWGGGKVVR 209
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
17-183 5.00e-03

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 38.08  E-value: 5.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  17 VWRLNTE-GTLTlvqVVDVPGQVQPMVISPDKR-FLYVGVRPEFRVlaYRISPDDGALTYTAEAPLPGSPTHISTDRKGN 94
Cdd:COG4257   40 IGRLDPAtGEFT---EYPLGGGSGPHGIAVDPDgNLWFTDNGNNRI--GRIDPKTGEITTFALPGGGSNPHGIAFDPDGN 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052363  95 FVFSGSYNAgcvSVTRL--EDGIpVETVDVVEGLEGCHSANISPDNRtLWvpalkqdriclFTLSDDGHLVAQNPA--EV 170
Cdd:COG4257  115 LWFTDQGGN---RIGRLdpATGE-VTEFPLPTGGAGPYGIAVDPDGN-LW-----------VTDFGANAIGRIDPDtgTL 178

                        170
                 ....*....|....*..
gi 697052363 171 TTVE----GAGPRHMVF 183
Cdd:COG4257  179 TEYAlptpGAGPRGLAV 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH