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Conserved domains on  [gi|697052228|ref|WP_033144834|]
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MULTISPECIES: ABC transporter ATP-binding protein [Enterobacter]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11467437)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates including Fe(3+) ions and polyamines such as spermidine and putrescine

CATH:  3.40.50.300
EC:  7.-.-.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0005524|GO:0016887
PubMed:  25750732|24638992
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-341 2.39e-124

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


:

Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 360.95  E-value: 2.39e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLE-GLADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 238 VILPAQLAAGYA--VCALG---EVPTDNAQATGQ-GRVMMRPEQLRVTAcAAHESPIS--ILDVDFTGQLSTLTLGLAGQ 309
Cdd:COG3842  240 NLLPGTVLGDEGggVRTGGrtlEVPADAGLAAGGpVTVAIRPEDIRLSP-EGPENGLPgtVEDVVFLGSHVRYRVRLGDG 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 697052228 310 QQPVILKTVSQ-PGWNPGTAVRIDI-AGTARVFE 341
Cdd:COG3842  319 QELVVRVPNRAaLPLEPGDRVGLSWdPEDVVVLP 352
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-341 2.39e-124

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 360.95  E-value: 2.39e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLE-GLADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 238 VILPAQLAAGYA--VCALG---EVPTDNAQATGQ-GRVMMRPEQLRVTAcAAHESPIS--ILDVDFTGQLSTLTLGLAGQ 309
Cdd:COG3842  240 NLLPGTVLGDEGggVRTGGrtlEVPADAGLAAGGpVTVAIRPEDIRLSP-EGPENGLPgtVEDVVFLGSHVRYRVRLGDG 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 697052228 310 QQPVILKTVSQ-PGWNPGTAVRIDI-AGTARVFE 341
Cdd:COG3842  319 QELVVRVPNRAaLPLEPGDRVGLSWdPEDVVVLP 352
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 2-216 2.48e-97

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 287.11  E-value: 2.48e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKlrgVPKAEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03259  156 EPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 2-319 7.19e-85

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 260.35  E-value: 7.19e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIGF 81
Cdd:TIGR03265   5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKRDYGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   82 VPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03265  81 VFQSYALFPNLTVADNIAYGLKNrgmGRAEVAERVAELLDLVGLPGS-ERKYPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDAV 238
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVN 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  239 ILPAQLAAGYAVcALGEVPTDNAQATGQ----GRVMMRPEQLRVT-ACAAHES-PISILDVDFTGQLSTLTLGLAGQQQP 312
Cdd:TIGR03265 240 WLPGTRGGGSRA-RVGGLTLACAPGLAQpgasVRLAVRPEDIRVSpAGNAANLlLARVEDMEFLGAFYRLRLRLEGLPGQ 318


                  ....*..
gi 697052228  313 VILKTVS 319
Cdd:TIGR03265 319 ALVADVS 325
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-278 1.05e-80

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 250.25  E-value: 1.05e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITH----VPAENRHVNT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLdgtRHEK------RQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK09452  91 VFQSYALFPHMTVFENVAFGL---RMQKtpaaeiTPRVMEALRMVQLE-EFAQRKPHQLSGGQQQRVAIARAVVNKPKVL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 156 LLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:PRK09452 167 LLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIG 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 236 DAVILPAQLAAGYA-----------VCalgEVPTDNAQATGQG-RVMMRPEQLRV 278
Cdd:PRK09452 247 EINIFDATVIERLDeqrvranvegrEC---NIYVNFAVEPGQKlHVLLRPEDLRV 298
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-162 1.33e-46

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 155.11  E-value: 1.33e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQEGALFPHLNVAD 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228   97 NIAWGLDG---TRHEKRQRVEALMEMVSLDRQLATHW---PHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:pfam00005  79 NLRLGLLLkglSKREKDARAEEALEKLGLGDLADRPVgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
1-212 7.67e-40

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 139.85  E-value: 7.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:NF038007   1 MLNMQNAEKCYItktiKTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RR--IGFVPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQR 151
Cdd:NF038007  81 RRelIGYIFQSFNLIPHLSIFDNVALPLkyrGVAKKERIERVNQVLNLFGIDNR-RNHKPMQLSGGQQQRVAIARAMVSN 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 152 PSLMLLDEPFSALD-TGLRAMTRKATAdlLAEAGVASILVTHdQNEALSFATQVAVMRSGRF 212
Cdd:NF038007 160 PALLLADEPTGNLDsKNARAVLQQLKY--INQKGTTIIMVTH-SDEASTYGNRIINMKDGKL 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
10-199 2.48e-33

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 121.96  E-value: 2.48e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdensfvpahlRRIGFVPQEGAL- 88
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVp 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 --FPhLNVADNIAWGLDGTR-------HEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:NF040873  68 dsLP-LTVRDLVAMGRWARRglwrrltRDDRAAVDDALERVGLAD-LAGRQLGELSGGQRQRALLAQGLAQEADLLLLDE 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 697052228 160 PFSALDtglrAMTRKATADLLAEA---GVASILVTHDQNEALS 199
Cdd:NF040873 146 PTTGLD----AESRERIIALLAEEharGATVVVVTHDLELVRR 184
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-229 1.21e-26

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 109.88  E-value: 1.21e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG------FEtpdtGRIVMQGRtlfdensfvPA 74
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGE---------VC 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRRI------GFV--PQEGALFPHLNVADNIAWGLDGTR------HEKRQRVEALMEMVSLDRQLATHWPHeISGGQQQ 140
Cdd:NF040905  68 RFKDIrdsealGIViiHQELALIPYLSIAENIFLGNERAKrgvidwNETNRRARELLAKVGLDESPDTLVTD-IGVGKQQ 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 141 RVALARALAQRPSLMLLDEPFSAL---DTglramtrKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRftQ 214
Cdd:NF040905 147 LVEIAKALSKDVKLLILDEPTAALneeDS-------AALLDLLLElkaQGITSIIISHKLNEIRRVADSITVLRDGR--T 217

                        250
                 ....*....|....*
gi 697052228 215 VGTpYDVYTRPVDEE 229
Cdd:NF040905 218 IET-LDCRADEVTED 231
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-160 1.29e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 71.69  E-value: 1.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfetpdtGRIVMQGR-TLFDENSFVPAHLR---- 77
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAG------ARKIQQGRvEVLGGDMADARHRRavcp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQ--EGALFPHLNVADNIA-----WGLDgtRHEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALAR 146
Cdd:NF033858  77 RIAYMPQglGKNLYPTLSVFENLDffgrlFGQD--AAERRRRIDELLRATGLapfaDRPAG-----KLSGGMKQKLGLCC 149

                        170
                 ....*....|....
gi 697052228 147 ALAQRPSLMLLDEP 160
Cdd:NF033858 150 ALIHDPDLLILDEP 163
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 26-202 2.05e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 63.93  E-value: 2.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    26 PGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqgrtlfdensfvpahlrrigfvpqegalfphlnvadniawgLDGT 105
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----------------------------------------IDGE 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   106 RHEKRQRVEALMEMVsldrqlaTHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRK-----ATADLL 180
Cdd:smart00382  40 DILEEVLDQLLLIIV-------GGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrLLLLLK 112

                          170       180
                   ....*....|....*....|..
gi 697052228   181 AEAGVASILVTHDQNEALSFAT 202
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGPALL 134
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-224 1.87e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 64.37  E-value: 1.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLlRILAGFETPDTGRIVMQGRTLFDENSfvpAHLRRIGF 81
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TWCANRR---ALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 -VPQEGALFPHLNVADN---IAWGLDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:NF000106  90 hRPVR*GRRESFSGRENlymIGR*LDLSRKDARARADELLERFSLT-EAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYL 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPfsalDTGLRAMTRKATAD---LLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:NF000106 169 DEP----TTGLDPRTRNEVWDevrSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
34-218 5.04e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 45.12  E-value: 5.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  34 GPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFvpAHLRRIGFVPQEGALFPHLNVADNIA-----WGLdgTRHE 108
Cdd:NF033858 299 GSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV-DAGDI--ATRRRVGYMSQAFSLYGELTVRQNLElharlFHL--PAAE 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 109 KRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASI 188
Cdd:NF033858 374 IAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIF 452

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 189 LVTHDQNEAL-----SFatqvavMRSGRFTQVGTP 218
Cdd:NF033858 453 ISTHFMNEAErcdriSL------MHAGRVLASDTP 481
GguA NF040905
sugar ABC transporter ATP-binding protein;
135-213 8.59e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 37.85  E-value: 8.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 135 SGGQQQRVALARALAQRPSLMLLDEPFSALDTGlramtrkatA--------DLLAEAGVASILVTHDQNEALSFATQVAV 206
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVG---------AkyeiytiiNELAAEGKGVIVISSELPELLGMCDRIYV 476


                 ....*..
gi 697052228 207 MRSGRFT 213
Cdd:NF040905 477 MNEGRIT 483
 
Name Accession Description Interval E-value
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-341 2.39e-124

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 360.95  E-value: 2.39e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIG 80
Cdd:COG3842    5 ALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG----LPPEKRNVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3842   81 MVFQDYALFPHLTVAENVAFGLRMrgvPKAEIRARVAELLELVGLE-GLADRYPHQLSGGQQQRVALARALAPEPRVLLL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDA 237
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEIYERPATRFVADFIGEA 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 238 VILPAQLAAGYA--VCALG---EVPTDNAQATGQ-GRVMMRPEQLRVTAcAAHESPIS--ILDVDFTGQLSTLTLGLAGQ 309
Cdd:COG3842  240 NLLPGTVLGDEGggVRTGGrtlEVPADAGLAAGGpVTVAIRPEDIRLSP-EGPENGLPgtVEDVVFLGSHVRYRVRLGDG 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 697052228 310 QQPVILKTVSQ-PGWNPGTAVRIDI-AGTARVFE 341
Cdd:COG3842  319 QELVVRVPNRAaLPLEPGDRVGLSWdPEDVVVLP 352
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 2-340 3.50e-113

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 332.50  E-value: 3.50e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFdenSFVPAHLRRIGF 81
Cdd:COG1118    3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF---TNLPPRERRVGF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG1118   80 VFQHYALFPHMTVAENIAFGLRvrpPSKAEIRARVEELLELVQLE-GLADRYPSQLSGGQRQRVALARALAVEPEVLLLD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDAV 238
Cdd:COG1118  159 EPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFLGCVN 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 239 ILPAQLAAGYAVCALGEVPTDNAQATGQGRVMMRPEQLRVTACAAHESPIS--ILDVDFTGQLSTLTLGLAGQQQPVILK 316
Cdd:COG1118  239 VLRGRVIGGQLEADGLTLPVAEPLPDGPAVAGVRPHDIEVSREPEGENTFPatVARVSELGPEVRVELKLEDGEGQPLEA 318

                        330       340
                 ....*....|....*....|....*....
gi 697052228 317 TVSQPGW-----NPGTAVRIDIAgTARVF 340
Cdd:COG1118  319 EVTKEAWaelglAPGDPVYLRPR-PARVF 346
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-340 1.75e-98

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 295.06  E-value: 1.75e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHlRRIG 80
Cdd:COG3839    3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGR---DVTDLPPKD-RNIA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3839   79 MVFQSYALYPHMTVYENIAFPLklrKVPKAEIDRRVREAAELLGLE-DLLDRKPKQLSGGQRQRVALGRALVREPKVFLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGD- 236
Cdd:COG3839  158 DEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEELYDRPANLFVAGFIGSp 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 237 -AVILPAQLAAGYAVCALGEVPTDNAQATGQGR---VMMRPEQLRVTACAAHESPISILDVDFTGQLSTLTLGLAGqqQP 312
Cdd:COG3839  238 pMNLLPGTVEGGGVRLGGVRLPLPAALAAAAGGevtLGIRPEHLRLADEGDGGLEATVEVVEPLGSETLVHVRLGG--QE 315

                        330       340
                 ....*....|....*....|....*....
gi 697052228 313 VILKTVSQPGWNPGTAVRIDI-AGTARVF 340
Cdd:COG3839  316 LVARVPGDTRLRPGDTVRLAFdPERLHLF 344
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 2-216 2.48e-97

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 287.11  E-value: 2.48e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:cd03259    1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTG----VPPERRNIGM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03259   77 VFQDYALFPHLTVAENIAFGLKlrgVPKAEIRARVRELLELVGLEG-LLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03259  156 EPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
PhnT2 TIGR03265
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ...
 2-319 7.19e-85

putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274496 [Multi-domain]  Cd Length: 353  Bit Score: 260.35  E-value: 7.19e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIGF 81
Cdd:TIGR03265   5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDI----TRLPPQKRDYGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   82 VPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03265  81 VFQSYALFPNLTVADNIAYGLKNrgmGRAEVAERVAELLDLVGLPGS-ERKYPGQLSGGQQQRVALARALATSPGLLLLD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDAV 238
Cdd:TIGR03265 160 EPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVADFVGEVN 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  239 ILPAQLAAGYAVcALGEVPTDNAQATGQ----GRVMMRPEQLRVT-ACAAHES-PISILDVDFTGQLSTLTLGLAGQQQP 312
Cdd:TIGR03265 240 WLPGTRGGGSRA-RVGGLTLACAPGLAQpgasVRLAVRPEDIRVSpAGNAANLlLARVEDMEFLGAFYRLRLRLEGLPGQ 318


                  ....*..
gi 697052228  313 VILKTVS 319
Cdd:TIGR03265 319 ALVADVS 325
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 2-235 2.51e-83

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 252.16  E-value: 2.51e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:cd03300    1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITN----LPPHKRPVNT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLDGTRHEK---RQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03300   77 VFQNYALFPHLTVFENIAFGLRLKKLPKaeiKERVAEALDLVQLE-GYANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:cd03300  156 EPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYEEPANRFVADFIG 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
2-278 1.05e-80

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 250.25  E-value: 1.05e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:PRK09452  15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITH----VPAENRHVNT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLdgtRHEK------RQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK09452  91 VFQSYALFPHMTVFENVAFGL---RMQKtpaaeiTPRVMEALRMVQLE-EFAQRKPHQLSGGQQQRVAIARAVVNKPKVL 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 156 LLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:PRK09452 167 LLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVARFIG 246

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 236 DAVILPAQLAAGYA-----------VCalgEVPTDNAQATGQG-RVMMRPEQLRV 278
Cdd:PRK09452 247 EINIFDATVIERLDeqrvranvegrEC---NIYVNFAVEPGQKlHVLLRPEDLRV 298
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 2-236 2.86e-79

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 241.86  E-value: 2.86e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFVPAHLRRIGF 81
Cdd:cd03296    3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGE----DATDVPVQERNVGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLD-------GTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:cd03296   79 VFQHYALFRHMTVFDNVAFGLRvkprserPPEAEIRAKVHELLKLVQLD-WLADRYPAQLSGGQRQRVALARALAVEPKV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:cd03296  158 LLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSFL 237


                 ..
gi 697052228 235 GD 236
Cdd:cd03296  238 GE 239
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-221 6.43e-79

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 241.92  E-value: 6.43e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHL 76
Cdd:COG1116    7 ALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKP-------VTGPG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG1116   80 PDRGVVFQEPALLPWLTVLDNVALGLELrgvPKAERRERARELLELVGLA-GFEDAYPHQLSGGMRQRVAIARALANDPE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 154 LMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMrSGRFTQVGTPYDV 221
Cdd:COG1116  159 VLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL-SARPGRIVEEIDV 225
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 2-211 6.18e-77

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 235.44  E-value: 6.18e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHLR 77
Cdd:cd03293    1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEP-------VTGPGP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQEGALFPHLNVADNIAWGLDGTRH---EKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:cd03293   74 DRGYVFQQDALLPWLTVLDNVALGLELQGVpkaEARERAEELLELVGLSG-FENAYPHQLSGGMRQRVALARALAVDPDV 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVM--RSGR 211
Cdd:cd03293  153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLsaRPGR 211
3a0106s01 TIGR00968
sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]
 2-240 6.81e-76

sulfate ABC transporter, ATP-binding protein; [Transport and binding proteins, Anions]


Pssm-ID: 130041 [Multi-domain]  Cd Length: 237  Bit Score: 233.54  E-value: 6.81e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFVPAHLRRIGF 81
Cdd:TIGR00968   1 IEIANISKRFGSFQALDDVNLEVPTGSLVALLGPSGSGKSTLLRIIAGLEQPDSGRIRLNGQ----DATRVHARDRKIGF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   82 VPQEGALFPHLNVADNIAWGLDGTRH---EKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR00968  77 VFQHYALFKHLTVRDNIAFGLEIRKHpkaKIKARVEELLELVQLEG-LGDRYPNQLSGGQRQRVALARALAVEPQVLLLD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDAV 238
Cdd:TIGR00968 156 EPFGALDAKVRKELRSWLRKLHDEVHVTTVFVTHDQEEAMEVADRIVVMSNGKIEQIGSPDEVYDHPANPFVMSFLGEVN 235


                  ..
gi 697052228  239 IL 240
Cdd:TIGR00968 236 VL 237
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 1-235 1.53e-74

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 229.88  E-value: 1.53e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIG 80
Cdd:COG1126    1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLRRKVG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIA----WGLDGTRHEKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG1126   81 MVFQQFNLFPHLTVLENVTlapiKVKKMSKAEAEERAMELLERVGLaDK--ADAYPAQLSGGQQQRVAIARALAMEPKVM 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 156 LLDEPFSALD---TG--LRAMTRkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET 230
Cdd:COG1126  159 LFDEPTSALDpelVGevLDVMRD------LAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHERT 232


                 ....*
gi 697052228 231 ALFLG 235
Cdd:COG1126  233 RAFLS 237
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
2-311 2.98e-74

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 233.05  E-value: 2.98e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIGF 81
Cdd:PRK10851   3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV----SRLHARDRKVGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLDG-TRHEK------RQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK10851  79 VFQHYALFRHMTVFDNIAFGLTVlPRRERpnaaaiKAKVTQLLEMVQLAH-LADRYPAQLSGGQKQRVALARALAVEPQI 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:PRK10851 158 LLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQVWREPATRFVLEFM 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 235 G-----DAVILPAQLAAGYAVCALGEVPTDnaqatgQGRV--MMRPEQLRVTACAAHES--PISILDVDFTGQLSTLTLG 305
Cdd:PRK10851 238 GevnrlQGTIRGGQFHVGAHRWPLGYTPAY------QGPVdlFLRPWEVDISRRTSLDSplPVQVLEVSPKGHYWQLVVQ 311


                 ....*.
gi 697052228 306 LAGQQQ 311
Cdd:PRK10851 312 PLGWYN 317
OpuBA COG1125
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 1-235 4.01e-73

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440742 [Multi-domain]  Cd Length: 306  Bit Score: 228.44  E-value: 4.01e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQV-LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRR- 78
Cdd:COG1125    1 MIEFENVTKRYPDGTVaVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLD---PVELRRr 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIA-------WgldgTRHEKRQRVEALMEMVSLDR-QLATHWPHEISGGQQQRVALARALAQ 150
Cdd:COG1125   78 IGYVIQQIGLFPHMTVAENIAtvprllgW----DKERIRARVDELLELVGLDPeEYRDRYPHELSGGQQQRVGVARALAA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 RPSLMLLDEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:COG1125  154 DPPILLMDEPFGALD----PITREQLQDELlrlqRELGKTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPA 229


                 ....*....
gi 697052228 227 DEETALFLG 235
Cdd:COG1125  230 NDFVADFVG 238
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-309 9.89e-72

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 226.52  E-value: 9.89e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvpAHLRRIGF 81
Cdd:PRK11432   7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRS----IQQRDICM 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSL----DRqlathWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK11432  83 VFQSYALFPHMSLGENVGYGLKMlgvPKEERKQRVKEALELVDLagfeDR-----YVDQISGGQQQRVALARALILKPKV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:PRK11432 158 LLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPASRFMASFM 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 235 GDAVILPAQLAAGYAVCALGEVPTDNAQAT----GQGRVMMRPEQLRVTACAAHESPISILDVDFTGQLSTLTLGLAGQ 309
Cdd:PRK11432 238 GDANIFPATLSGDYVDIYGYRLPRPAAFAFnlpdGECTVGVRPEAITLSEQGEESQRCTIKHVAYMGPQYEVTVDWHGQ 316
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 32-314 6.76e-71

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 223.52  E-value: 6.76e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   32 IVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIGFVPQEGALFPHLNVADNIAWGL--DGT-RHE 108
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV----TNVPPHLRHINMVFQSYALFPHMTVEENVAFGLkmRKVpRAE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  109 KRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASI 188
Cdd:TIGR01187  77 IKPRVLEALRLVQLE-EFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITFV 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  189 LVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGDAVILPAQL---AAGYAVCALGEVPTDNA---- 261
Cdd:TIGR01187 156 FVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEINVFEATVierKSEQVVLAGVEGRRCDIytdv 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  262 --QATGQGRVMMRPEQLRVTACAAHES----PISILDVDFTGQLSTLTLGLAGQQQPVI 314
Cdd:TIGR01187 236 pvEKDQPLHVVLRPEKIVIEEEDEANSsnaiIGHVIDITYLGMTLEVHVRLETGQKVLV 294
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 2-216 1.22e-70

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 219.05  E-value: 1.22e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:cd03301    1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTD----LPPKDRDIAM 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03301   77 VFQNYALYPHMTVYDNIAFGLklrKVPKDEIDERVREVAELLQIE-HLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03301  156 EPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 2-235 1.26e-69

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 217.20  E-value: 1.26e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQvLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGF 81
Cdd:cd03299    1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITN----LPPEKRDISY 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLDGTRHEKRQRVEALMEMVS-------LDRQLAThwpheISGGQQQRVALARALAQRPSL 154
Cdd:cd03299   76 VPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEmlgidhlLNRKPET-----LSGGEQQRVAIARALVVNPKI 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:cd03299  151 LLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFL 230


                 .
gi 697052228 235 G 235
Cdd:cd03299  231 G 231
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 19-216 2.73e-69

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 215.62  E-value: 2.73e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  19 SLNLS-VAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD--ENSFVPAHLRRIGFVPQEGALFPHLNVA 95
Cdd:cd03297   14 TLKIDfDLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDsrKKINLPPQQRKIGLVFQQYALFPHLNVR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWGLDGTRH-EKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRK 174
Cdd:cd03297   94 ENLAFGLKRKRNrEDRISVDELLDLLGLD-HLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLP 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 697052228 175 ATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03297  173 ELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1-235 3.95e-69

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 220.86  E-value: 3.95e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIG 80
Cdd:PRK11607  19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDL----SHVPPYQRPIN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK11607  95 MMFQSYALFPHMTVEQNIAFGLKQdklPKAEIASRVNEMLGLVHM-QEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLL 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:PRK11607 174 DEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIG 251
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 1-319 8.47e-67

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 214.19  E-value: 8.47e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELtAISKSFSDVQvLDsLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENS--FVPAHLRR 78
Cdd:COG4148    2 MLEV-DFRLRRGGFT-LD-VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDSARgiFLPPHRRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGLDGTRHEKRQ-RVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG4148   79 IGYVFQEARLFPHLSVRGNLLYGRKRAPRAERRiSFDEVVELLGIGH-LLDRRPATLSGGERQRVAIGRALLSSPRLLLM 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDtglraMTRKatADLL-------AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET 230
Cdd:COG4148  158 DEPLAALD-----LARK--AEILpylerlrDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPDLLPL 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 231 ALFLGDAVILPAQLAA-----GYAVCALGEVP---TDNAQATGQG---RVMMR--------PEQL--------RVTACAA 283
Cdd:COG4148  231 AGGEEAGSVLEATVAAhdpdyGLTRLALGGGRlwvPRLDLPPGTRvrvRIRARdvslalepPEGSsilnilpgRVVEIEP 310

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 697052228 284 HESPISILDVDFTGQ--LSTLT------LGLA-GQQQPVILKTVS 319
Cdd:COG4148  311 ADGGQVLVRLDLGGQtlLARITrrsadeLGLApGQTVYAQIKSVA 355
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 2-235 3.52e-66

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 208.69  E-value: 3.52e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQ-VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-I 79
Cdd:cd03295    1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGE---DIREQDPVELRRkI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIA-------WGldgtRHEKRQRVEALMEMVSLD-RQLATHWPHEISGGQQQRVALARALAQR 151
Cdd:cd03295   78 GYVIQQIGLFPHMTVEENIAlvpkllkWP----KEKIRERADELLALVGLDpAEFADRYPHELSGGQQQRVGVARALAAD 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 152 PSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETA 231
Cdd:cd03295  154 PPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVA 233


                 ....
gi 697052228 232 LFLG 235
Cdd:cd03295  234 EFVG 237
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 1-218 1.60e-65

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 206.75  E-value: 1.60e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHL---- 76
Cdd:COG1127    5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLS---EKELyelr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPHLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRP 152
Cdd:COG1127   82 RRIGMLFQGGALFDSLTVFENVAFPLrehtDLSEAEIRELVLEKLELVGL-PGAADKMPSELSGGMRKRVALARALALDP 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 153 SLMLLDEPFSALDtglrAMTRKATADLLAE----AGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG1127  161 EILLYDEPTAGLD----PITSAVIDELIRElrdeLGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTP 226
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 2-211 2.98e-65

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 203.96  E-value: 2.98e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGF 81
Cdd:cd03229    1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRIGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGLdgtrhekrqrvealmemvsldrqlathwpheiSGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03229   81 VFQDFALFPHLTVLENIALGL--------------------------------SGGQQQRVALARALAMDPDVLLLDEPT 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 697052228 162 SALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03229  129 SALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-211 4.23e-65

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 205.28  E-value: 4.23e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:COG1136    4 LLELRNLTKSYgtgeGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RR--IGFVPQEGALFPHLNVADNIA--WGLDGT-RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQR 151
Cdd:COG1136   84 RRrhIGFVFQFFNLLPELTALENVAlpLLLAGVsRKERRERARELLERVGLG-DRLDHRPSQLSGGQQQRVAIARALVNR 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 152 PSLMLLDEPFSALDTglraMTRKATADLL----AEAGVASILVTHDQnEALSFATQVAVMRSGR 211
Cdd:COG1136  163 PKLILADEPTGNLDS----KTGEEVLELLrelnRELGTTIVMVTHDP-ELAARADRVIRLRDGR 221
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-230 5.83e-65

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 213.61  E-value: 5.83e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF-----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAH 75
Cdd:COG1123  260 LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 LRR-IGFVPQ--EGALFPHLNVADNIAWGLD----GTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARAL 148
Cdd:COG1123  340 LRRrVQMVFQdpYSSLNPRMTVGDIIAEPLRlhglLSRAERRERVAELLERVGLPPDLADRYPHELSGGQRQRVAIARAL 419

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 149 AQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDE 228
Cdd:COG1123  420 ALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHP 499


                 ..
gi 697052228 229 ET 230
Cdd:COG1123  500 YT 501
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 1-242 6.15e-62

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 198.10  E-value: 6.15e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdENSFVPAHL 76
Cdd:COG1124    1 MLEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV--TRRRRKAFR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQ--EGALFPHLNVADNIAWGLDGTRH-EKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG1124   79 RRVQMVFQdpYASLHPRHTVDRILAEPLRIHGLpDREERIAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIARALILEPE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 154 LMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALF 233
Cdd:COG1124  159 LLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHPYTREL 238


                 ....*....
gi 697052228 234 LGDAVILPA 242
Cdd:COG1124  239 LAASLAFER 247
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 2-211 1.02e-60

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 193.86  E-value: 1.02e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLR 77
Cdd:cd03255    1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 R--IGFVPQEGALFPHLNVADNIAWGLDGTRH---EKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRP 152
Cdd:cd03255   81 RrhIGFVFQSFNLLPDLTALENVELPLLLAGVpkkERRERAEELLERVGLG-DRLNHYPSELSGGQQQRVAIARALANDP 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEAlSFATQVAVMRSGR 211
Cdd:cd03255  160 KIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIELRDGK 217
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-235 1.21e-59

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 191.51  E-value: 1.21e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVldSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRRIG 80
Cdd:COG3840    1 MLRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDL----TALPPAERPVS 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLD-GTR--HEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG3840   75 MLFQENNLFPHLTVAQNIGLGLRpGLKltAEQRAQVEQALERVGLA-GLLDRLPGQLSGGQRQRVALARCLVRKRPILLL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:COG3840  154 DEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAYLG 231
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 2-221 6.43e-59

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 189.64  E-value: 6.43e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLR-RIG 80
Cdd:cd03261    1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRrRMG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03261   81 MLFQSGALFDSLTVFENVAFPLrehtRLSEEEIREIVLEKLEAVGL-RGAEDLYPAELSGGMKKRVALARALALDPELLL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 157 LDEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:cd03261  160 YDEPTAGLD----PIASGVIDDLIrslkKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEEL 224
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2-239 4.43e-58

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 187.58  E-value: 4.43e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVpahLRRIGF 81
Cdd:COG1131    1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEV---RRRIGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAW-----GLDgtRHEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:COG1131   78 VPQEPALYPDLTVRENLRFfarlyGLP--RKEARERIDELLELFGLTD-AADRKVGTLSGGMKQRLGLALALLHDPELLI 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 157 LDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPydvytrpvDEETALFLGD 236
Cdd:COG1131  155 LDEPTSGLDPEARRELWELLRE-LAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTP--------DELKARLLED 225


                 ...
gi 697052228 237 AVI 239
Cdd:COG1131  226 VFL 228
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-230 5.72e-58

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 187.60  E-value: 5.72e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHLRRIG 80
Cdd:COG1121    6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP-------PRRARRRIG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGAL---FPhLNVADNIAWGLDGTR-------HEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALAR 146
Cdd:COG1121   79 YVPQRAEVdwdFP-ITVRDVVLMGRYGRRglfrrpsRADREAVDEALERVGLedlaDRPIG-----ELSGGQQQRVLLAR 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 147 ALAQRPSLMLLDEPFSALDtglrAMTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRFTQvGTPYDVYT 223
Cdd:COG1121  153 ALAQDPDLLLLDEPFAGVD----AATEEALYELLRElrrEGKTILVVTHDLGAVREYFDRVLLLNRGLVAH-GPPEEVLT 227


                 ....*..
gi 697052228 224 RPVDEET 230
Cdd:COG1121  228 PENLSRA 234
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 2-211 1.62e-57

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 185.43  E-value: 1.62e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGF 81
Cdd:cd03262    1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELRQKVGM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNI------AWGLDgtRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:cd03262   81 VFQQFNLFPHLTVLENItlapikVKGMS--KAEAEERALELLEKVGLADK-ADAYPAQLSGGQQQRVAIARALAMNPKVM 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 156 LLDEPFSALD---TG--LRAMTRkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03262  158 LFDEPTSALDpelVGevLDVMKD------LAEEGMTMVVVTHEMGFAREVADRVIFMDDGR 212
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-234 3.20e-56

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 182.99  E-value: 3.20e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIG 80
Cdd:PRK09493   1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWG----LDGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK09493  81 MVFQQFYLFPHLTALENVMFGplrvRGASKEEAEKQARELLAKVGL-AERAHHYPSELSGGQQQRVAIARALAVKPKLML 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 157 LDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:PRK09493 160 FDEPTSALDPELRHEVLKVMQD-LAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
2-212 5.09e-56

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 181.55  E-value: 5.09e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR-IG 80
Cdd:COG4619    1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPL---SAMPPPEWRRqVA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHlNVADNIA--WGLDGtRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG4619   78 YVPQEPALWGG-TVRDNLPfpFQLRE-RKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIRALLLQPDVLLLD 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRF 212
Cdd:COG4619  156 EPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 1-223 1.35e-55

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 181.78  E-value: 1.35e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL-RRI 79
Cdd:COG1120    1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDL---ASLSRRELaRRI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIAWG-------LDGTRHEKRQRVEALMEMVSL----DRQLathwpHEISGGQQQRVALARAL 148
Cdd:COG1120   78 AYVPQEPPAPFGLTVRELVALGryphlglFGRPSAEDREAVEEALERTGLehlaDRPV-----DELSGGERQRVLIARAL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 149 AQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:COG1120  153 AQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLT 227
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-277 1.43e-55

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 185.05  E-value: 1.43e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS-DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHlRRI 79
Cdd:PRK11650   3 GLKLQAVRKSYDgKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVV---NELEPAD-RDI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIAWGLD--GT-RHEKRQRVEALMEMVS----LDRQlathwPHEISGGQQQRVALARALAQRP 152
Cdd:PRK11650  79 AMVFQNYALYPHMSVRENMAYGLKirGMpKAEIEERVAEAARILEleplLDRK-----PRELSGGQRQRVAMGRAIVREP 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETAL 232
Cdd:PRK11650 154 AVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVEVYEKPASTFVAS 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 233 FLGDAVI--LPAQLAAGYAVCALG---EVPTDNAQATGQGRVM---MRPEQLR 277
Cdd:PRK11650 234 FIGSPAMnlLDGRVSADGAAFELAggiALPLGGGYRQYAGRKLtlgIRPEHIA 286
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 2-225 5.32e-55

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 179.45  E-value: 5.32e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSD-VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIG 80
Cdd:COG1122    1 IELENLSFSYPGgTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKN--LRELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQ--EGALFpHLNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG1122   79 LVFQnpDDQLF-APTVEEDVAFGpenLGLPREEIRERVEEALELVGLE-HLADRPPHELSGGQKQRVAIAGVLAMEPEVL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 156 LLDEPFSALDtglrAMTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:COG1122  157 VLDEPTAGLD----PRGRRELLELLKRlnkEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 1-211 6.83e-55

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 179.24  E-value: 6.83e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVPAH 75
Cdd:cd03257    1 LLEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKlSRRLRKIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 LRRIGFVPQE--GALFPHLNVADNIA-----WGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARAL 148
Cdd:cd03257   81 RKEIQMVFQDpmSSLNPRMTIGEQIAeplriHGKLSKKEARKEAVLLLLVGVGLPEEVLNRYPHELSGGQRQRVAIARAL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 149 AQRPSLMLLDEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03257  161 ALNPKLLIADEPTSALD----VSVQAQILDLLkklqEELGLTLLFITHDLGVVAKIADRVAVMYAGK 223
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-246 7.19e-55

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 182.58  E-value: 7.19e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL 76
Cdd:COG1135    1 MIELENLSKTFPtkggPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDL---TALSEREL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 R----RIGFVPQEGALFPHLNVADNIA-----WGLDgtRHEKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALAR 146
Cdd:COG1135   78 RaarrKIGMIFQHFNLLSSRTVAENVAlpleiAGVP--KAEIRKRVAELLELVGLsDK--ADAYPSQLSGGQKQRVGIAR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 147 ALAQRPSLMLLDEPFSALDTGlramTRKATADLLAEA----GVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:COG1135  154 ALANNPKVLLCDEATSALDPE----TTRSILDLLKDInrelGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVF 229

                        250       260
                 ....*....|....*....|....*.
gi 697052228 223 TRPVDEETALFLGDAV--ILPAQLAA 246
Cdd:COG1135  230 ANPQSELTRRFLPTVLndELPEELLA 255
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 1-198 3.00e-54

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 176.90  E-value: 3.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD---TGRIVMQGRTLFDensfVPAHLR 77
Cdd:COG4136    1 MLSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTA----LPAEQR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQEGALFPHLNVADNIAWGLDGT--RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG4136   77 RIGILFQDDLLFPHLSVGENLAFALPPTigRAQRRARVEQALEEAGLA-GFADRDPATLSGGQRARVALLRALLAEPRAL 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 697052228 156 LLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEAL 198
Cdd:COG4136  156 LLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDAP 198
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 3-211 3.56e-53

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 174.19  E-value: 3.56e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSD--VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIG 80
Cdd:cd03225    1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLS--LKELRRKVG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQ--EGALFpHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQRPSLM 155
Cdd:cd03225   79 LVFQnpDDQFF-GPTVEEEVAFGLENlglPEEEIEERVEEALELVGLEGLRDRS-PFTLSGGQKQRVAIAGVLAMDPDIL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 156 LLDEPFSALDtglrAMTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03225  157 LLDEPTAGLD----PAGRRELLELLKKlkaEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
4-235 6.83e-53

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 178.30  E-value: 6.83e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfVPAHLRRIGFVP 83
Cdd:PRK11000   6 LRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMND----VPPAERGVGMVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHLNVADNIAWGLD---GTRHEKRQRVEALMEMVSL----DRQlathwPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK11000  82 QSYALYPHLSVAENMSFGLKlagAKKEEINQRVNQVAEVLQLahllDRK-----PKALSGGQRQRVAIGRTLVAEPSVFL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 157 LDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:PRK11000 157 LDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPANRFVAGFIG 235
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-211 2.11e-52

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 172.54  E-value: 2.11e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS-DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVPAHLRR 78
Cdd:COG2884    1 MIRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlKRREIPYLRRR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGLD--GT-RHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG2884   81 IGVVFQDFRLLPDRTVYENVALPLRvtGKsRKEIRRRVREVLDLVGLSDK-AKALPHELSGGEQQRVAIARALVNRPELL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 156 LLDEPFSALD--TGLRAMtrkataDLLAE---AGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:COG2884  160 LADEPTGNLDpeTSWEIM------ELLEEinrRGTTVLIATHDLELVDRMPKRVLELEDGR 214
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 1-229 2.23e-52

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 173.12  E-value: 2.23e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRRIG 80
Cdd:COG4555    1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEP---REARRQIG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNI-----AWGLDGtrHEKRQRVEALMEMVSLDRQLATHWpHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG4555   78 VLPDERGLYDRLTVRENIryfaeLYGLFD--EELKKRIEELIELLGLEEFLDRRV-GELSTGMKKKVALARALVHDPKVL 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 156 LLDEPFSALDtglrAMTRKATADLL---AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEE 229
Cdd:COG4555  155 LLDEPTNGLD----VMARRLLREILralKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEEN 227
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 5-236 2.35e-52

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 173.98  E-value: 2.35e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   5 TAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLR-----RI 79
Cdd:cd03294   28 EEILKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQ---DIAAMSRKELRelrrkKI 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIAWGLD--G-TRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03294  105 SMVFQSFALLPHRTVLENVAFGLEvqGvPRAEREERAAEALELVGLE-GWEHKYPDELSGGMQQRVGLARALAVDPDILL 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 157 LDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGD 236
Cdd:cd03294  184 MDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRG 263
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-215 1.67e-51

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 171.58  E-value: 1.67e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfvPAHL 76
Cdd:COG4525    3 MLTVRHVSVRYpgggQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-----PGAD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RriGFVPQEGALFPHLNVADNIAWGLD--GT-RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPS 153
Cdd:COG4525   78 R--GVVFQKDALLPWLNVLDNVAFGLRlrGVpKAERRARAEELLALVGLA-DFARRRIWQLSGGMRQRVGIARALAADPR 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 154 LMLLDEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVM--RSGRFTQV 215
Cdd:COG4525  155 FLLMDEPFGALD----ALTREQMQELLldvwQRTGKGVFLITHSVEEALFLATRLVVMspGPGRIVER 218
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 1-211 1.69e-51

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 171.01  E-value: 1.69e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF-SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLR-- 77
Cdd:COG3638    2 MLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDV---TALRGRALRrl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 --RIGFVPQEGALFPHLNVADNIAWGLDGTRH-----------EKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVAL 144
Cdd:COG3638   79 rrRIGMIFQQFNLVPRLSVLTNVLAGRLGRTStwrsllglfppEDRERALEALERVGLA-DKAYQRADQLSGGQQQRVAI 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 145 ARALAQRPSLMLLDEPFSALD--TGLRAMtrkataDLLAEA----GVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:COG3638  158 ARALVQEPKLILADEPVASLDpkTARQVM------DLLRRIaredGITVVVNLHQVDLARRYADRIIGLRDGR 224
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 2-218 9.61e-51

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 168.51  E-value: 9.61e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:cd03260    1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDVLELR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPhLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLDRQLATH-WPHEISGGQQQRVALARALAQR 151
Cdd:cd03260   81 RRVGMVFQKPNPFP-GSIYDNVAYGLrlhgIKLKEELDERVEEALRKAALWDEVKDRlHALGLSGGQQQRLCLARALANE 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 152 PSLMLLDEPFSALDtglramtRKATA---DLLAEAG--VASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:cd03260  160 PEVLLLDEPTSALD-------PISTAkieELIAELKkeYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 2-212 2.13e-50

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 165.65  E-value: 2.13e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPahlRRIGF 81
Cdd:cd03230    1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVK---RRIGY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIawgldgtrhekrqrvealmemvsldrqlathwphEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03230   78 LPEEPSLYENLTVRENL----------------------------------KLSGGMKQRLALAQALLHDPELLILDEPT 123

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 697052228 162 SALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRF 212
Cdd:cd03230  124 SGLDPESRREFWELLRE-LKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 20-226 2.55e-50

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 171.06  E-value: 2.55e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   20 LNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD--ENSFVPAHLRRIGFVPQEGALFPHLNVADN 97
Cdd:TIGR02142  16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrKGIFLPPEKRRIGYVFQEARLFPHLSVRGN 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   98 IAWGLDGTRHEKRQ-RVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKAT 176
Cdd:TIGR02142  96 LRYGMKRARPSERRiSFERVIELLGIG-HLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYL 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 697052228  177 ADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:TIGR02142 175 ERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPD 224
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 1-211 2.93e-50

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 167.23  E-value: 2.93e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLF--DENSFvpA 74
Cdd:COG4181    8 IIELRGLTKTVGTgageLTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFalDEDAR--A 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRR--IGFVPQEGALFPHLNVADNIAWGLDGTRH-EKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQR 151
Cdd:COG4181   86 RLRArhVGFVFQSFQLLPTLTALENVMLPLELAGRrDARARARALLERVGLG-HRLDHYPAQLSGGEQQRVALARAFATE 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 152 PSLMLLDEPFSALDTGlramTRKATADLL----AEAGVASILVTHDQNEALSFATQVAvMRSGR 211
Cdd:COG4181  165 PAILFADEPTGNLDAA----TGEQIIDLLfelnRERGTTLVLVTHDPALAARCDRVLR-LRAGR 223
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 1-225 4.02e-49

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 164.29  E-value: 4.02e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR--TLFDENSFVPA 74
Cdd:cd03258    1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTdlTLLSGKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HlRRIGFVPQEGALFPHLNVADNIA-----WGLDgtRHEKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALARAL 148
Cdd:cd03258   81 R-RRIGMIFQHFNLLSSRTVFENVAlpleiAGVP--KAEIEERVLELLELVGLeDK--ADAYPAQLSGGQKQRVGIARAL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 149 AQRPSLMLLDEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:cd03258  156 ANNPKVLLCDEATSALD----PETTQSILALLrdinRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFAN 231


                 .
gi 697052228 225 P 225
Cdd:cd03258  232 P 232
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-309 1.11e-48

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 170.85  E-value: 1.11e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF--SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD---TGRIVMQGRTLFDENSFVPAh 75
Cdd:COG1123    4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALRG- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 lRRIGFVPQE--GALFPhLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQ 150
Cdd:COG1123   83 -RRIGMVFQDpmTQLNP-VTVGDQIAEALenlGLSRAEARARVLELLEAVGLER-RLDRYPHQLSGGQRQRVAIAMALAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRpvdeet 230
Cdd:COG1123  160 DPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAA------ 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 231 alflgdavilPAQLAagyAVCALGEVPTDNAQATGQGRVMMRPEQLRVTACAAHESPISIL-DVDFT---GQlstlTLGL 306
Cdd:COG1123  234 ----------PQALA---AVPRLGAARGRAAPAAAAAEPLLEVRNLSKRYPVRGKGGVRAVdDVSLTlrrGE----TLGL 296


                 ...
gi 697052228 307 AGQ 309
Cdd:COG1123  297 VGE 299
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 3-207 2.83e-48

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 161.55  E-value: 2.83e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvpahlRRIGFV 82
Cdd:cd03235    1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKER-------KRIGYV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  83 PQEGAL---FPhLNVADNIAWGLDGT-------RHEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALARAL 148
Cdd:cd03235   74 PQRRSIdrdFP-ISVRDVVLMGLYGHkglfrrlSKADKAKVDEALERVGLselaDRQIG-----ELSGGQQQRVLLARAL 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 149 AQRPSLMLLDEPFSALDtglrAMTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVM 207
Cdd:cd03235  148 VQDPDLLLLDEPFAGVD----PKTQEDIYELLRElrrEGMTILVVTHDLGLVLEYFDRVLLL 205
proV TIGR01186
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ...
 17-236 4.39e-48

glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130254 [Multi-domain]  Cd Length: 363  Bit Score: 165.80  E-value: 4.39e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLR-----RIGFVPQEGALFPH 91
Cdd:TIGR01186   9 VNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIEPTAGQIFIDGENIMKQS---PVELRevrrkKIGMVFQQFALFPH 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   92 LNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:TIGR01186  86 MTILQNTSLGPEllgWPEQERKEKALELLKLVGLE-EYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLI 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228  169 RAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGD 236
Cdd:TIGR01186 165 RDSMQDELKKLQATLQKTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGK 232
ProV COG4175
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ...
 21-228 3.91e-47

ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443334 [Multi-domain]  Cd Length: 389  Bit Score: 163.74  E-value: 3.91e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  21 NLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLR-----RIGFVPQEGALFPHLNVA 95
Cdd:COG4175   47 SFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAGEVLIDGEDITKLS---KKELRelrrkKMSMVFQHFALLPHRTVL 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWGLD--GT-RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD------- 165
Cdd:COG4175  124 ENVAFGLEiqGVpKAERRERAREALELVGLA-GWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDplirrem 202

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 166 ----TGLRAMTRKATadllaeagvasILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDE 228
Cdd:COG4175  203 qdelLELQAKLKKTI-----------VFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPAND 258
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 15-225 5.35e-47

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 160.31  E-value: 5.35e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQ--EGALFpH 91
Cdd:TIGR04521  19 KALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDLRKkVGLVFQfpEHQLF-E 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   92 LNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtgl 168
Cdd:TIGR04521  98 ETVYKDIAFGpknLGLSEEEAEERVKEALELVGLDEEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLD--- 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228  169 rAMTRKATADLLA----EAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:TIGR04521 175 -PKGRKEILDLFKrlhkEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV 234
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 17-162 1.33e-46

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 155.11  E-value: 1.33e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQEGALFPHLNVAD 96
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE--RKSLRKEIGYVFQDPQLFPRLTVRE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228   97 NIAWGLDG---TRHEKRQRVEALMEMVSLDRQLATHW---PHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:pfam00005  79 NLRLGLLLkglSKREKDARAEEALEKLGLGDLADRPVgerPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 1-193 1.56e-46

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 156.87  E-value: 1.56e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDEnsfVPAHLRRIG 80
Cdd:COG4133    2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDA---REDYRRRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAW--GLDGTRHEkRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG4133   79 YLGHADGLKPELTVRENLRFwaALYGLRAD-REAIDEALEAVGLAG-LADLPVRQLSAGQKRRVALARLLLSPAPLWLLD 156

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAeAGVASILVTHD 193
Cdd:COG4133  157 EPFTALDAAGVALLAELIAAHLA-RGGAVLLTTHQ 190
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 20-211 3.94e-46

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 156.11  E-value: 3.94e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  20 LNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFVPAHLRRIGFVPQEGALFPHLNVADNIA 99
Cdd:cd03298   17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGV----DVTAAPPADRPVSMLFQENNLFAHLTVEQNVG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 100 WGLDGTRH---EKRQRVEALMEMVSLDRQLAtHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKAT 176
Cdd:cd03298   93 LGLSPGLKltaEDRQAIEVALARVGLAGLEK-RLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLV 171

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 177 ADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03298  172 LDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 2-228 2.17e-45

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 155.03  E-value: 2.17e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSF-SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQG-RTLFDENSFVPAHLRRI 79
Cdd:cd03256    1 IEVENLSKTYpNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGtDINKLKGKALRQLRRQI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIAWGLDGTRH-----------EKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARAL 148
Cdd:cd03256   81 GMIFQQFNLIERLSVLENVLSGRLGRRStwrslfglfpkEEKQRALAALERVGLL-DKAYQRADQLSGGQQQRVAIARAL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 149 AQRPSLMLLDEPFSALDTglrAMTRKATADLLA---EAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:cd03256  160 MQQPKLILADEPVASLDP---ASSRQVMDLLKRinrEEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDEV 236


                 ...
gi 697052228 226 VDE 228
Cdd:cd03256  237 LDE 239
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-217 9.19e-45

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 159.80  E-value: 9.19e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFVPAHLRRIG 80
Cdd:COG1129    4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPV-RFRSPRDAQAAGIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTRH------EKRQRVEALMEMVSLD---RQLAThwphEISGGQQQRVALARALAQR 151
Cdd:COG1129   83 IIHQELNLVPNLSVAENIFLGREPRRGglidwrAMRRRARELLARLGLDidpDTPVG----DLSVAQQQLVEIARALSRD 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 152 PSLMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRFtqVGT 217
Cdd:COG1129  159 ARVLILDEPTASL-------TEREVERLfriirrLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL--VGT 221
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
1-226 1.27e-44

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 153.35  E-value: 1.27e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL-RRI 79
Cdd:COG4559    1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPL---AAWSPWELaRRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGAL-FPhLNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDRQLATHWPhEISGGQQQRVALARALAQ----- 150
Cdd:COG4559   78 AVLPQHSSLaFP-FTVEEVVALGRAphgSSAAQDRQIVREALALVGLAHLAGRSYQ-TLSGGEQQRVQLARVLAQlwepv 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 --RPSLMLLDEPFSALDTG--LRAMTrkaTADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:COG4559  156 dgGPRWLFLDEPTSALDLAhqHAVLR---LARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDEL 232
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 2-221 5.00e-44

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 151.44  E-value: 5.00e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLR-RIG 80
Cdd:cd03219    1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDI----TGLPPHEIaRLG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVP--QEGALFPHLNVADNI-------------AWGLDGTRHEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALA 145
Cdd:cd03219   77 IGRtfQIPRLFPELTVLENVmvaaqartgsgllLARARREEREARERAEELLERVGLADLADRP-AGELSYGQQRRLEIA 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 146 RALAQRPSLMLLDEPFSaldtGLRAMTRKATADL---LAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:cd03219  156 RALATDPKLLLLDEPAA----GLNPEETEELAELireLRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEV 230
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-234 1.08e-43

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 151.06  E-value: 1.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI------VMQGRTLFDENSFVPA 74
Cdd:PRK11264   3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditIDTARSLSQQKGLIRQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRRIGFVPQEGALFPHLNVADNIAWGLDGTRHEKRQRVEA----LMEMVSLDRQlATHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK11264  83 LRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATArareLLAKVGLAGK-ETSYPRRLSGGQQQRVAIARALAM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRkATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET 230
Cdd:PRK11264 162 RPEVILFDEPTSALDPELVGEVL-NTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRT 240


                 ....
gi 697052228 231 ALFL 234
Cdd:PRK11264 241 RQFL 244
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 3-216 1.31e-43

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 148.35  E-value: 1.31e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL-RRIGF 81
Cdd:cd03214    1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDL---ASLSPKELaRKIAY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQegALfphlnvadniawgldgtrhekrqrveALMEMVSL-DRQLathwpHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:cd03214   78 VPQ--AL--------------------------ELLGLAHLaDRPF-----NELSGGERQRVLLARALAQEPPILLLDEP 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 161 FSALDTG--------LRAMTRkatadllaEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03214  125 TSHLDIAhqiellelLRRLAR--------ERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1-234 1.62e-43

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 150.72  E-value: 1.62e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FDEN---SFVPA-- 74
Cdd:COG4598    8 ALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIrLKPDrdgELVPAdr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 ----HLR-RIGFVPQEGALFPHLNVADNIAWG----LDGTRHEKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVAL 144
Cdd:COG4598   88 rqlqRIRtRLGMVFQSFNLWSHMTVLENVIEApvhvLGRPKAEAIERAEALLAKVGLaDK--RDAYPAHLSGGQQQRAAI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 145 ARALAQRPSLMLLDEPFSALD---TG--LRAMtRKatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:COG4598  166 ARALAMEPEVMLFDEPTSALDpelVGevLKVM-RD-----LAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPA 239

                        250
                 ....*....|....*
gi 697052228 220 DVYTRPVDEETALFL 234
Cdd:COG4598  240 EVFGNPKSERLRQFL 254
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
21-211 1.78e-43

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 149.73  E-value: 1.78e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  21 NLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHlRRIGFVPQEGALFPHLNVADNIAW 100
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQ---DHTTTPPSR-RPVSMLFQENNLFSHLTVAQNIGL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 101 GLD-GTR--HEKRQRVEALMEMVSLDRQLaTHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATA 177
Cdd:PRK10771  95 GLNpGLKlnAAQREKLHAIARQMGIEDLL-ARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVS 173

                        170       180       190
                 ....*....|....*....|....*....|....
gi 697052228 178 DLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK10771 174 QVCQERQLTLLMVSHSLEDAARIAPRSLVVADGR 207
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 1-223 1.95e-43

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 150.31  E-value: 1.95e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL-RRI 79
Cdd:PRK13548   2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPL---ADWSPAELaRRR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGAL-FPhLNVADNIAWGLD---GTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQ----- 150
Cdd:PRK13548  79 AVLPQHSSLsFP-FTVEEVVAMGRAphgLSRAEDDALVAAALAQVDLA-HLAGRDYPQLSGGEQQRVQLARVLAQlwepd 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 151 -RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:PRK13548 157 gPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLT 230
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 3-211 1.97e-43

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 147.01  E-value: 1.97e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvPAHLRRIGFV 82
Cdd:cd00267    1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPL--EELRRRIGYV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  83 PQegalfphlnvadniawgldgtrhekrqrvealmemvsldrqlathwpheISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:cd00267   79 PQ-------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 697052228 163 ALDTGLRAMTRKATADLLAEaGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd00267  110 GLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDGK 157
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 2-211 2.28e-43

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 147.53  E-value: 2.28e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSD--VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR- 78
Cdd:cd03228    1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV---DLRDLDLESLRKn 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFpHLNVADNIawgldgtrhekrqrvealmemvsldrqlathwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03228   78 IAYVPQDPFLF-SGTIRENI-----------------------------------LSGGQRQRIAIARALLRDPPILILD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVasILVTHDQnEALSFATQVAVMRSGR 211
Cdd:cd03228  122 EATSALDPETEALILEALRALAKGKTV--IVIAHRL-STIRDADRIIVLDDGR 171
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 1-221 3.22e-43

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 149.80  E-value: 3.22e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLR-RI 79
Cdd:COG0411    4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDI----TGLPPHRIaRL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 G----FvpQEGALFPHLNVADNIA------------------WGLDGTRHEKRQRVEALMEMVSLDRqLATHWPHEISGG 137
Cdd:COG0411   80 GiartF--QNPRLFPELTVLENVLvaaharlgrgllaallrlPRARREEREARERAEELLERVGLAD-RADEPAGNLSYG 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 138 QQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:COG0411  157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGT 236


                 ....
gi 697052228 218 PYDV 221
Cdd:COG0411  237 PAEV 240
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 17-229 3.38e-43

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 149.15  E-value: 3.38e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfvPAHLRRIGFvpQEGALFPHLNVAD 96
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITE-----PGPDRMVVF--QNYSLLPWLTVRE 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   97 NIAWGLDGTRH-----EKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAM 171
Cdd:TIGR01184  74 NIALAVDRVLPdlsksERRAIVEEHIALVGL-TEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALD----AL 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228  172 TRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV-YTRPVDEE 229
Cdd:TIGR01184 149 TRGNLQEELmqiwEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQILEVpFPRPRDRL 211
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 16-218 4.14e-43

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 158.07  E-value: 4.14e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR-IGFVPQEGALFpHLNV 94
Cdd:COG2274  490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDL---RQIDPASLRRqIGVVLQDVFLF-SGTI 565

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGLDGTRHEkrqRVEALMEMVSLDRQLATHwPH-----------EISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:COG2274  566 RENITLGDPDATDE---EIIEAARLAGLHDFIEAL-PMgydtvvgeggsNLSGGQRQRLAIARALLRNPRILILDEATSA 641

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 164 LDtglrAMTRKATADLLAE--AGVASILVTHDQnEALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG2274  642 LD----AETEAIILENLRRllKGRTVIIIAHRL-STIRLADRIIVLDKGRIVEDGTH 693
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-211 1.12e-42

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 149.49  E-value: 1.12e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtLFDENSFVPAHLRRIG 80
Cdd:COG4152    1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEV------LWDGEPLDPEDRRRIG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAW-----GLDgtRHEKRQRVEALmemvsLDR-QLATHWPHEI---SGGQQQRVALARALAQR 151
Cdd:COG4152   75 YLPEERGLYPKMKVGEQLVYlarlkGLS--KAEAKRRADEW-----LERlGLGDRANKKVeelSKGNQQKVQLIAALLHD 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 152 PSLMLLDEPFSALD--------TGLRAmtrkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:COG4152  148 PELLILDEPFSGLDpvnvellkDVIRE---------LAAKGTTVIFSSHQMELVEELCDRIVIINKGR 206
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 1-246 1.43e-42

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 150.72  E-value: 1.43e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR--TLFDENSFVPA 74
Cdd:PRK11153   1 MIELKNISKVFPqggrTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQdlTALSEKELRKA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HlRRIGFVpqegalFPHLN------VADNIAWGL--DGT-RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALA 145
Cdd:PRK11153  81 R-RQIGMI------FQHFNllssrtVFDNVALPLelAGTpKAEIKARVTELLELVGLS-DKADRYPAQLSGGQKQRVAIA 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 146 RALAQRPSLMLLDEPFSALDTGlramTRKATADLLA----EAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:PRK11153 153 RALASNPKVLLCDEATSALDPA----TTRSILELLKdinrELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEV 228

                        250       260
                 ....*....|....*....|....*..
gi 697052228 222 YTRPVDEETALFLGDA--VILPAQLAA 246
Cdd:PRK11153 229 FSHPKHPLTREFIQSTlhLDLPEDYLA 255
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 4-194 4.32e-42

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 145.45  E-value: 4.32e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR--IGF 81
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRRekLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   82 VPQEGALFPHLNVADNIAWGLDGTR---HEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKYKKlskKEKREKKKEALEKVGLNLKLKQK-IYELSGGEQQRVALARAILKPPPLILAD 159

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 697052228  159 EPFSALDTglraMTRKATADLL---AEAGVASILVTHDQ 194
Cdd:TIGR03608 160 EPTGSLDP----KNRDEVLDLLlelNDEGKTIIIVTHDP 194
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 1-225 5.15e-42

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 148.28  E-value: 5.15e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETP---DTGRIVMQGRTL--FDENSF 71
Cdd:COG0444    1 LLEVRNLKVYFPtrrgVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLlkLSEKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  72 VPAHLRRIGFVPQE--GALFPHLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLD--RQLATHWPHEISGGQQQRVA 143
Cdd:COG0444   81 RKIRGREIQMIFQDpmTSLNPVMTVGDQIAEPLrihgGLSKAEARERAIELLERVGLPdpERRLDRYPHELSGGMRQRVM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 144 LARALAQRPSLMLLDEPFSALDTGLRA-----MtrkatADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG0444  161 IARALALEPKLLIADEPTTALDVTIQAqilnlL-----KDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPV 235


                 ....*..
gi 697052228 219 YDVYTRP 225
Cdd:COG0444  236 EELFENP 242
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 2-211 9.65e-42

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 145.98  E-value: 9.65e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvMQGRTLFdensfvpAHLR---R 78
Cdd:PRK11247  13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGTAPL-------AEARedtR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFvpQEGALFPHLNVADNIAWGLDGtrHEKRQRVEALmEMVSL-DRqlATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK11247  85 LMF--QDARLLPWKKVIDNVGLGLKG--QWRDAALQAL-AAVGLaDR--ANEWPAALSGGQKQRVALARALIHRPGLLLL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 158 DEPFSALDtglrAMTRKATADLLA----EAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK11247 158 DEPLGALD----ALTRIEMQDLIEslwqQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 2-218 1.02e-41

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 144.88  E-value: 1.02e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLR-R-- 78
Cdd:cd03224    1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDI----TGLPPHERaRag 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGL-DGTRHEKRQRVEALMEM----VSLDRQLATHwpheISGGQQQRVALARALAQRPS 153
Cdd:cd03224   77 IGYVPEGRRIFPELTVEENLLLGAyARRRAKRKARLERVYELfprlKERRKQLAGT----LSGGEQQMLAIARALMSRPK 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 154 LMLLDEPFSAL-----DTGLRAMTRkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:cd03224  153 LLLLDEPSEGLapkivEEIFEAIRE------LRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTA 216
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
1-210 1.08e-41

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 146.00  E-value: 1.08e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensfvPAHLRriG 80
Cdd:PRK11248   1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEG-----PGAER--G 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTRHEKRQRVEALMEM---VSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK11248  74 VVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMlkkVGLE-GAEKRYIWQLSGGQRQRVGIARALAANPQLLLL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 158 DEPFSALDtglrAMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSG 210
Cdd:PRK11248 153 DEPFGALD----AFTREQMQTLLlklwQETGKQVLLITHDIEEAVFMATELVLLSPG 205
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 21-216 1.56e-41

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 144.23  E-value: 1.56e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   21 NLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFVPAHLRRIGFVPQEGALFPHLNVADNIAW 100
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQ----SHTGLAPYQRPVSMLFQENNLFAHLTVRQNIGL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  101 GLDGT---RHEKRQRVEALMEMVSLDRQLAtHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATA 177
Cdd:TIGR01277  94 GLHPGlklNAEQQEKVVDAAQQVGIADYLD-RLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVK 172

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 697052228  178 DLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:TIGR01277 173 QLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 14-225 2.68e-41

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 146.80  E-value: 2.68e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQE--GALFP 90
Cdd:COG4608   31 VKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRPLRRrMQMVFQDpyASLNP 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HLNVADNIAWGLD----GTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:COG4608  111 RMTVGDIIAEPLRihglASKAERRERVAELLELVGLRPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDV 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 167 GLRAMTRKATADLLAEAGVASILVTHDqneaLS----FATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:COG4608  191 SIQAQVLNLLEDLQDELGLTYLFISHD----LSvvrhISDRVAVMYLGKIVEIAPRDELYARP 249
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
2-234 2.80e-41

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 144.39  E-value: 2.80e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlFDENSFVPAH----LR 77
Cdd:COG4161    3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQ-FDFSQKPSEKairlLR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 R-IGFVPQEGALFPHLNVADNI----AWGLDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRP 152
Cdd:COG4161   82 QkVGMVFQQYNLWPHLTVMENLieapCKVLGLSKEQAREKAMKLLARLRLT-DKADRFPLHLSGGQQQRVAIARALMMEP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPyDVYTRPVDEETAL 232
Cdd:COG4161  161 QVLLFDEPTAALDPEITAQVVEIIRE-LSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDA-SHFTQPQTEAFAH 238


                 ..
gi 697052228 233 FL 234
Cdd:COG4161  239 YL 240
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 2-211 1.05e-40

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 141.65  E-value: 1.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtLFDENSFVPAHLRRIGF 81
Cdd:cd03269    1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEV------LFDGKPLDIAARNRIGY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAW--GLDG-TRHEKRQRVEALMEMVSL----DRQLathwpHEISGGQQQRVALARALAQRPSL 154
Cdd:cd03269   75 LPEERGLYPKMKVIDQLVYlaQLKGlKKEEARRRIDEWLERLELseyaNKRV-----EELSKGNQQKVQFIAAVIHDPEL 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03269  150 LILDEPFSGLDPVNVELLKDVIRE-LARAGKTVILSTHQMELVEELCDRVLLLNKGR 205
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 13-218 2.41e-40

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 148.75  E-value: 2.41e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR-IGFVPQEGALFpH 91
Cdd:COG4988  349 GRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDL---SDLDPASWRRqIAWVPQNPYLF-A 424

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LNVADNIAWGL-DGTRHEKRQRVEA--LMEMV-SLDRQLAThwphEI-------SGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:COG4988  425 GTIRENLRLGRpDASDEELEAALEAagLDEFVaALPDGLDT----PLgeggrglSGGQAQRLALARALLRDAPLLLLDEP 500

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 161 FSALDTGLRAMTRKATADLLAEAGVasILVTHDQnEALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG4988  501 TAHLDAETEAEILQALRRLAKGRTV--ILITHRL-ALLAQADRILVLDDGRIVEQGTH 555
ABC_ATP_DarD NF038007
darobactin export ABC transporter ATP-binding protein;
1-212 7.67e-40

darobactin export ABC transporter ATP-binding protein;


Pssm-ID: 411600 [Multi-domain]  Cd Length: 218  Bit Score: 139.85  E-value: 7.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:NF038007   1 MLNMQNAEKCYItktiKTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKEVTNLSYSQKIIL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RR--IGFVPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQR 151
Cdd:NF038007  81 RRelIGYIFQSFNLIPHLSIFDNVALPLkyrGVAKKERIERVNQVLNLFGIDNR-RNHKPMQLSGGQQQRVAIARAMVSN 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 152 PSLMLLDEPFSALD-TGLRAMTRKATAdlLAEAGVASILVTHdQNEALSFATQVAVMRSGRF 212
Cdd:NF038007 160 PALLLADEPTGNLDsKNARAVLQQLKY--INQKGTTIIMVTH-SDEASTYGNRIINMKDGKL 218
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 1-246 2.06e-39

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 145.55  E-value: 2.06e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FDEnsfvPAHLRR- 78
Cdd:COG3845    5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVrIRS----PRDAIAl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 -IGFVPQEGALFPHLNVADNIAWGLDGT------RHEKRQRVEALMEM----VSLDRQLathwpHEISGGQQQRVALARA 147
Cdd:COG3845   81 gIGMVHQHFMLVPNLTVAENIVLGLEPTkggrldRKAARARIRELSERygldVDPDAKV-----EDLSVGEQQRVEILKA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 148 LAQRPSLMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRFtqVGTpydV 221
Cdd:COG3845  156 LYRGARILILDEPTAVL-------TPQEADELfeilrrLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV--VGT---V 223

                        250       260
                 ....*....|....*....|....*..
gi 697052228 222 YTRPVDEE--TALFLGDAVILPAQLAA 246
Cdd:COG3845  224 DTAETSEEelAELMVGREVLLRVEKAP 250
3a0107s01c2 TIGR00972
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ...
 2-234 4.63e-39

phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]


Pssm-ID: 273372 [Multi-domain]  Cd Length: 247  Bit Score: 138.58  E-value: 4.63e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdTGRIVMQGRTLFDENSFVPA 74
Cdd:TIGR00972   2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLnrmndlvPGVRI--EGKVLFDGQDIYDKKIDVVE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   75 HLRRIGFVPQEGALFPhLNVADNIAWGLD----GTRHEKRQRVEALMEMVSL-----DRqLATHwPHEISGGQQQRVALA 145
Cdd:TIGR00972  80 LRRRVGMVFQKPNPFP-MSIYDNIAYGPRlhgiKDKKELDEIVEESLKKAALwdevkDR-LHDS-ALGLSGGQQQRLCIA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  146 RALAQRPSLMLLDEPFSALDTglrAMTRK--ATADLLAEAgVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:TIGR00972 157 RALAVEPEVLLLDEPTSALDP---IATGKieELIQELKKK-YTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFT 232

                         250
                  ....*....|.
gi 697052228  224 RPVDEETALFL 234
Cdd:TIGR00972 233 NPKEKRTEDYI 243
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
10-218 8.62e-39

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 144.92  E-value: 8.62e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFS---DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-IGFVPQE 85
Cdd:COG1132  346 SFSypgDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGV---DIRDLTLESLRRqIGVVPQD 422

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 GALFpHLNVADNIAWG-LDGTRHEkrqrVEALMEMVSLDrQLATHWPH-----------EISGGQQQRVALARALAQRPS 153
Cdd:COG1132  423 TFLF-SGTIRENIRYGrPDATDEE----VEEAAKAAQAH-EFIEALPDgydtvvgergvNLSGGQRQRIAIARALLKDPP 496

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 154 LMLLDEPFSALDTGLRAMTRKATADLLaeAGVASILVTHDqneaLS---FATQVAVMRSGRFTQVGTP 218
Cdd:COG1132  497 ILILDEATSALDTETEALIQEALERLM--KGRTTIVIAHR----LStirNADRILVLDDGRIVEQGTH 558
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 11-231 9.11e-39

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 138.25  E-value: 9.11e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdTGRIVMQGRTLFDENSFVPAHLRRIGFVP 83
Cdd:COG1117   21 YGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndliPGARV--EGEILLDGEDIYDPDVDVVELRRRVGMVF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHlNVADNIAWGL----DGTRHEKRQRVEALMEMVSL-----DR--QLAThwphEISGGQQQRVALARALAQRP 152
Cdd:COG1117   99 QKPNPFPK-SIYDNVAYGLrlhgIKSKSELDEIVEESLRKAALwdevkDRlkKSAL----GLSGGQQQRLCIARALAVEP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 153 SLMLLDEPFSALDTglramtrKATA---DLLAEAG--VASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVD 227
Cdd:COG1117  174 EVLLMDEPTSALDP-------ISTAkieELILELKkdYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTNPKD 246


                 ....
gi 697052228 228 EETA 231
Cdd:COG1117  247 KRTE 250
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-223 1.05e-38

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 137.91  E-value: 1.05e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTG-RIVMQGRTLFDENsfVPAHLRRI 79
Cdd:COG1119    3 LLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGED--VWELRKRI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALF--PHLNVADNIAWGLDGT----RH---EKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQ 150
Cdd:COG1119   81 GLVSPALQLRfpRDETVLDVVLSGFFDSiglyREptdEQRERARELLELLGLAH-LADRPFGTLSQGEQRRVLIARALVK 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:COG1119  160 DPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLT 232
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 2-218 1.28e-38

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 136.48  E-value: 1.28e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQ--VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRRI 79
Cdd:cd03263    1 LQIRNLTKTYKKGTkpAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYING---YSIRTDRKAARQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNI-----AWGLdgTRHEKRQRVEALMEMVSLDRQLatHWP-HEISGGQQQRVALARALAQRPS 153
Cdd:cd03263   78 GYCPQFDALFDELTVREHLrfyarLKGL--PKSEIKEEVELLLRVLGLTDKA--NKRaRTLSGGMKRKLSLAIALIGGPS 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 154 LMLLDEPFSALDtglrAMTRKATADLLAEAGVAS--ILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:cd03263  154 VLLLDEPTSGLD----PASRRAIWDLILEVRKGRsiILTTHSMDEAEALCDRIAIMSDGKLRCIGSP 216
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
1-216 3.03e-38

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 139.24  E-value: 3.03e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELtAISKSFSDVQVldSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD--ENSFVPAHLRR 78
Cdd:PRK11144   1 MLEL-NFKQQLGDLCL--TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDaeKGICLPPEKRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGLdgtRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK11144  78 IGYVFQDARLFPHYKVRGNLRYGM---AKSMVAQFDKIVALLGIE-PLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMD 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 159 EPFSALDtglraMTRKatADLLA-------EAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:PRK11144 154 EPLASLD-----LPRK--RELLPylerlarEINIPILYVSHSLDEILRLADRVVVLEQGKVKAFG 211
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 14-230 4.21e-38

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 142.52  E-value: 4.21e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFEtPDTGRIVMQGRTL--FDENSFVPahLRR-IGFVPQE--GAL 88
Cdd:COG4172  299 VKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLdgLSRRALRP--LRRrMQVVFQDpfGSL 375

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FPHLNVADNIAWGL-----DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:COG4172  376 SPRMTVGQIIAEGLrvhgpGLSAAERRARVAEALEEVGLDPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 164 LDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET 230
Cdd:COG4172  456 LDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHPYT 522
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 1-218 5.16e-38

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 135.49  E-value: 5.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRR-- 78
Cdd:COG0410    3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDI----TGLPPHRIArl 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 -IGFVPQEGALFPHLNVADNIAWGldGTRHEKRQRVEALMEMVsLD---------RQLAThwphEISGGQQQRVALARAL 148
Cdd:COG0410   79 gIGYVPEGRRIFPSLTVEENLLLG--AYARRDRAEVRADLERV-YElfprlkerrRQRAG----TLSGGEQQMLAIGRAL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 149 AQRPSLMLLDEPfSAldtGLRAMTRKATADL---LAEAGVASILVthDQN--EALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG0410  152 MSRPKLLLLDEP-SL---GLAPLIVEEIFEIirrLNREGVTILLV--EQNarFALEIADRAYVLERGRIVLEGTA 220
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 1-216 6.23e-38

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 134.80  E-value: 6.23e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD----VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHL 76
Cdd:cd03266    1 MITADALTKRFRDvkktVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDG---FDVVKEPAEAR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPHLNVADNIAW--GLDG-TRHEKRQRVEAL---MEMVS-LDRQLAthwphEISGGQQQRVALARALA 149
Cdd:cd03266   78 RRLGFVSDSTGLYDRLTARENLEYfaGLYGlKGDELTARLEELadrLGMEElLDRRVG-----GFSTGMRQKVAIARALV 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 150 QRPSLMLLDEPfsalDTGLRAMTRKATADL---LAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03266  153 HDPPVLLLDEP----TTGLDVMATRALREFirqLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 1-228 9.00e-38

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 135.12  E-value: 9.00e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    1 MLELTAISKSF-SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDEN-SFVPAHLRR 78
Cdd:TIGR02315   1 MLEVENLSKVYpNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRgKKLRKLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   79 IGFVPQEGALFPHLNVADNIAWGLDG------------TRHEKRQRVEALmEMVSLDrQLATHWPHEISGGQQQRVALAR 146
Cdd:TIGR02315  81 IGMIFQHYNLIERLTVLENVLHGRLGykptwrsllgrfSEEDKERALSAL-ERVGLA-DKAYQRADQLSGGQQQRVAIAR 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  147 ALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:TIGR02315 159 ALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDDEVL 238


                  ..
gi 697052228  227 DE 228
Cdd:TIGR02315 239 RH 240
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 1-211 1.01e-37

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 134.30  E-value: 1.01e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    1 MLELTAISKSF-SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVPAHLRR 78
Cdd:TIGR02673   1 MIEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRlRGRQLPLLRRR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   79 IGFVPQEGALFPHLNVADNIAWGLDGTRHEKR---QRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:TIGR02673  81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEReiqRRVGAALRQVGLeHK--ADAFPEQLSGGEQQRVAIARAIVNSPPL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228  155 MLLDEPFSALD--TGLRAMtrkataDLLAE---AGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:TIGR02673 159 LLADEPTGNLDpdLSERIL------DLLKRlnkRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 12-224 1.21e-37

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 135.64  E-value: 1.21e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQG-RTLFDENsfVPAHLRRIGFVPQE----- 85
Cdd:TIGR04520  13 SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGlDTLDEEN--LWEIRKKVGMVFQNpdnqf 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   86 -GALfphlnVADNIAWGLD--GT-RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:TIGR04520  91 vGAT-----VEDDVAFGLEnlGVpREEMRKRVDEALKLVGME-DFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEAT 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228  162 SALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALsFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:TIGR04520 165 SMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAEGTPREIFSQ 226
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 2-234 3.00e-37

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 133.60  E-value: 3.00e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlFDENSFVPAH----LR 77
Cdd:PRK11124   3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNH-FDFSKTPSDKaireLR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 R-IGFVPQEGALFPHLNVADNI------AWGLDgtRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK11124  82 RnVGMVFQQYNLWPHLTVQQNLieapcrVLGLS--KDQALARAEKLLERLRLK-PYADRFPLHLSGGQQQRVAIARALMM 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPyDVYTRPVDEET 230
Cdd:PRK11124 159 EPQVLLFDEPTAALDPEITAQIVSIIRE-LAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDA-SCFTQPQTEAF 236


                 ....
gi 697052228 231 ALFL 234
Cdd:PRK11124 237 KNYL 240
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 2-232 3.33e-37

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 133.44  E-value: 3.33e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRR--- 78
Cdd:cd03218    1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDI----TKLPMHKRArlg 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGLDGT---RHEKRQRVEALMEMVSLDR---QLATHwpheISGGQQQRVALARALAQRP 152
Cdd:cd03218   77 IGYLPQEASIFRKLTVEENILAVLEIRglsKKEREEKLEELLEEFHITHlrkSKASS----LSGGERRRVEIARALATNP 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 153 SLMLLDEPFSALDTglramtrKATADL------LAEAGVaSILVT-HDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:cd03218  153 KFLLLDEPFAGVDP-------IAVQDIqkiikiLKDRGI-GVLITdHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANE 224


                 ....*..
gi 697052228 226 VDEETAL 232
Cdd:cd03218  225 LVRKVYL 231
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 7-213 3.91e-37

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 132.38  E-value: 3.91e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQ-VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdeNSFVPAHLRRIGFVPQE 85
Cdd:cd03226    5 ISFSYKKGTeILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGK-----PIKAKERRKSIGYVMQD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 --GALFPHlNVADNIAWGLDGTrHEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03226   80 vdYQLFTD-SVREELLLGLKEL-DAGNEQAETVLKDLDLYALKERH-PLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSG 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 164 LDtgLRAMtrKATADL---LAEAGVASILVTHDQNEALSFATQVAVMRSGRFT 213
Cdd:cd03226  157 LD--YKNM--ERVGELireLAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 2-216 4.07e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 132.32  E-value: 4.07e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSrTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRRIGF 81
Cdd:cd03264    1 LQLENLTKRYGKKRALDGVSLTLGPGM-YGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQ---DVLKQPQKLRRRIGY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNV---ADNIAWgLDGTRH-EKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:cd03264   77 LPQEFGVYPNFTVrefLDYIAW-LKGIPSkEVKARVDEVLELVNLgDR--AKKKIGSLSGGMRRRVGIAQALVGDPSILI 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 157 LDEPFSALDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03264  154 VDEPTAGLDPEERIRFRNLLSELGEDRIV--ILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 1-222 6.04e-37

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 132.85  E-value: 6.04e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSrtaIV---GPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLR 77
Cdd:COG1137    3 TLEAENLVKSYGKRTVVKDVSLEVNQGE---IVgllGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI----THLPMHKR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 -R--IGFVPQEGALFPHLNVADNIA-----WGLDgtRHEKRQRVEALMEMVSLD---RQLAthwpHEISGGQQQRVALAR 146
Cdd:COG1137   76 aRlgIGYLPQEASIFRKLTVEDNILavlelRKLS--KKEREERLEELLEEFGIThlrKSKA----YSLSGGERRRVEIAR 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 147 ALAQRPSLMLLDEPFSALD----TGLRAMTRKatadlLAEAGVaSILVT-HDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:COG1137  150 ALATNPKFILLDEPFAGVDpiavADIQKIIRH-----LKERGI-GVLITdHNVRETLGICDRAYIISEGKVLAEGTPEEI 223


                 .
gi 697052228 222 Y 222
Cdd:COG1137  224 L 224
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 13-211 6.46e-37

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 132.15  E-value: 6.46e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVPAHLRRIGFVPQEGALFPH 91
Cdd:cd03292   13 GTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlRGRAIPYLRRKIGVVFQDFRLLPD 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LNVADNIAWGLDGTRH---EKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGl 168
Cdd:cd03292   93 RNVYENVAFALEVTGVpprEIRKRVPAALELVGL-SHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPD- 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 697052228 169 ramTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03292  171 ---TTWEIMNLLKKinkAGTTVVVATHAKELVDTTRHRVIALERGK 213
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 7-218 1.11e-36

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 131.72  E-value: 1.11e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPahlRRIGFVPQEG 86
Cdd:cd03265    6 LVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVR---RRIGIVFQDL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 ALFPHLNVADNIAW--GLDG-TRHEKRQRVEALMEMVSL----DRQLATHwpheiSGGQQQRVALARALAQRPSLMLLDE 159
Cdd:cd03265   83 SVDDELTGWENLYIhaRLYGvPGAERRERIDELLDFVGLleaaDRLVKTY-----SGGMRRRLEIARSLVHRPEVLFLDE 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 160 PFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:cd03265  158 PTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTP 216
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
15-222 1.53e-36

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 132.83  E-value: 1.53e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQE------GAl 88
Cdd:PRK13635  21 YALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEET--VWDVRRQVGMVFQNpdnqfvGA- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 fphlNVADNIAWGLDGT---RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13635  98 ----TVQDDVAFGLENIgvpREEMVERVDQALRQVGME-DFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 166 TGLRAMTRKATADLLAEAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13635 173 PRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIF 228
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 2-217 3.44e-36

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 128.32  E-value: 3.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFV-PAHLRRIG 80
Cdd:cd03216    1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEV----SFAsPRDARRAG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 fvpqegalfphlnvadniawgldgtrhekrqrvealMEMVsldrqlathwpHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:cd03216   77 ------------------------------------IAMV-----------YQLSVGERQMVEIARALARNARLLILDEP 109

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 161 FSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRftQVGT 217
Cdd:cd03216  110 TAAL-------TPAEVERLfkvirrLRAQGVAVIFISHRLDEVFEIADRVTVLRDGR--VVGT 163
SapF COG4167
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
2-230 3.78e-36

ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];


Pssm-ID: 443328 [Multi-domain]  Cd Length: 265  Bit Score: 131.50  E-value: 3.78e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSD---------VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FDENSF 71
Cdd:COG4167    5 LEVRNLSKTFKYrtglfrrqqFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGHKLeYGDYKY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  72 VPAHLRRIgFVPQEGALFPHLNVadniawG--LDG--------TRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQR 141
Cdd:COG4167   85 RCKHIRMI-FQDPNTSLNPRLNI------GqiLEEplrlntdlTAEEREERIFATLRLVGLLPEHANFYPHMLSSGQKQR 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 142 VALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:COG4167  158 VALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEV 237


                 ....*....
gi 697052228 222 YTRPVDEET 230
Cdd:COG4167  238 FANPQHEVT 246
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 2-218 6.18e-36

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 136.82  E-value: 6.18e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSF--SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR- 78
Cdd:COG4987  334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDL---RDLDEDDLRRr 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFpHLNVADNIAWGLDGTRHEkrqRVEALMEMVSLDRQLATH------WPHE----ISGGQQQRVALARAL 148
Cdd:COG4987  411 IAVVPQRPHLF-DTTLRENLRLARPDATDE---ELWAALERVGLGDWLAALpdgldtWLGEggrrLSGGERRRLALARAL 486

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 149 AQRPSLMLLDEPFSALDtglRAMTRKATADLLAEAGVAS-ILVTHDQnEALSFATQVAVMRSGRFTQVGTP 218
Cdd:COG4987  487 LRDAPILLLDEPTEGLD---AATEQALLADLLEALAGRTvLLITHRL-AGLERMDRILVLEDGRIVEQGTH 553
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 2-211 1.07e-35

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 128.86  E-value: 1.07e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQ--VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRR- 78
Cdd:cd03245    3 IEFRNVSFSYPNQEipALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDG---TDIRQLDPADLRRn 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFpHLNVADNIAWGLdgtRHEKRQRVEALMEMVSLDRQLATHwPH-----------EISGGQQQRVALARA 147
Cdd:cd03245   80 IGYVPQDVTLF-YGTLRDNITLGA---PLADDERILRAAELAGVTDFVNKH-PNgldlqigergrGLSGGQRQAVALARA 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 148 LAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVasILVTHdQNEALSFATQVAVMRSGR 211
Cdd:cd03245  155 LLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTL--IIITH-RPSLLDLVDRIIVMDSGR 215
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 2-211 1.63e-35

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 126.95  E-value: 1.63e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQ--VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR- 78
Cdd:cd03246    1 LEVENVSFRYPGAEppVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADI---SQWDPNELGDh 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHlNVADNIawgldgtrhekrqrvealmemvsldrqlathwpheISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03246   78 VGYLPQDDELFSG-SIAENI-----------------------------------LSGGQRQRLGLARALYGNPRILVLD 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAeAGVASILVTHdQNEALSFATQVAVMRSGR 211
Cdd:cd03246  122 EPNSHLDVEGERALNQAIAALKA-AGATRIVIAH-RPETLASADRILVLEDGR 172
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
1-214 2.95e-35

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 128.39  E-value: 2.95e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQ----VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:PRK11629   5 LLQCDNLCKRYQEGSvqtdVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAEL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 R--RIGFVPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK11629  85 RnqKLGFIYQFHHLLPDFTALENVAMPLligKKKPAEINSRALEMLAAVGLEHR-ANHRPSELSGGERQRVAIARALVNN 163

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 152 PSLMLLDEPFSALDtglrAMTRKATADLLAE----AGVASILVTHDQNEALSFATQVAvMRSGRFTQ 214
Cdd:PRK11629 164 PRLVLADEPTGNLD----ARNADSIFQLLGElnrlQGTAFLVVTHDLQLAKRMSRQLE-MRDGRLTA 225
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 14-225 3.98e-35

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 130.47  E-value: 3.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQE--GALFP 90
Cdd:PRK11308  28 VKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKLLRQkIQIVFQNpyGSLNP 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK11308 108 RKKVGQILEEPLlintSLSAAERREKALAMMAKVGLRPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDV 187

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 167 GLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK11308 188 SVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNP 246
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
15-242 1.87e-34

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 127.11  E-value: 1.87e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQE--GALFPH 91
Cdd:PRK10419  26 TVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAFRRdIQMVFQDsiSAVNPR 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LNVADNIAWGLdgtRH-------EKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:PRK10419 106 KTVREIIREPL---RHllsldkaERLARASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNL 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 165 DTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFtqvgtpydVYTRPVDEETAL------FLGDAV 238
Cdd:PRK10419 183 DLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQI--------VETQPVGDKLTFsspagrVLQNAV 254


                 ....
gi 697052228 239 iLPA 242
Cdd:PRK10419 255 -LPA 257
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 1-222 4.11e-34

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 130.96  E-value: 4.11e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqGRTLfdensfvpahlrRIG 80
Cdd:COG0488  315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV------------KIG 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALF-PHLNVADNIA-WGLDGTRHEKRQRVEALM---EMVsldRQLAthwpHEISGGQQQRVALARALAQRPSLM 155
Cdd:COG0488  382 YFDQHQEELdPDKTVLDELRdGAPGGTEQEVRGYLGRFLfsgDDA---FKPV----GVLSGGEKARLALAKLLLSPPNVL 454

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 156 LLDEPFSALDTglraMTRKATADLLAE-AGVAsILVTHDQnEAL-SFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:COG0488  455 LLDEPTNHLDI----ETLEALEEALDDfPGTV-LLVSHDR-YFLdRVATRILEFEDGGVREYPGGYDDY 517
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 4-193 4.64e-34

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 130.96  E-value: 4.64e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfvpahlrRIGFVP 83
Cdd:COG0488    1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL-------------RIGYLP 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHLNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLA------------------------------THWPH- 132
Cdd:COG0488   68 QEPPLDDDLTVLDTVLDGDAELRALEAELEELEAKLAEPDEDLErlaelqeefealggweaearaeeilsglgfPEEDLd 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 133 ----EISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAMTRKATADLLAEAGVASILVTHD 193
Cdd:COG0488  148 rpvsELSGGWRRRVALARALLSEPDLLLLDEPTNHLD----LESIEWLEEFLKNYPGTVLVVSHD 208
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 2-217 6.61e-34

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 124.56  E-value: 6.61e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHLRR--- 78
Cdd:TIGR03410   1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDI----TKLPPHERArag 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   79 IGFVPQEGALFPHLNVADNIAWGLDGTRHEKRQRVE-------ALMEMvsLDRQLAthwphEISGGQQQRVALARALAQR 151
Cdd:TIGR03410  77 IAYVPQGREIFPRLTVEENLLTGLAALPRRSRKIPDeiyelfpVLKEM--LGRRGG-----DLSGGQQQQLAIARALVTR 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228  152 PSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:TIGR03410 150 PKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGA 215
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 16-193 7.04e-34

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 130.48  E-value: 7.04e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensFVPAHLRR-IGFVPQEGALFPHlNV 94
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLAD---ADADSWRDqIAWVPQHPFLFAG-TI 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGL-DGTRHEKRQRVEA--LMEMVS-----LDRQLATHwPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:TIGR02857 413 AENIRLARpDASDAEIREALERagLDEFVAalpqgLDTPIGEG-GAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDA 491

                         170       180
                  ....*....|....*....|....*..
gi 697052228  167 GLRAMTRKATADLLaeAGVASILVTHD 193
Cdd:TIGR02857 492 ETEAEVLEALRALA--QGRTVLLVTHR 516
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 14-225 8.11e-34

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 130.57  E-value: 8.11e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKT----TLLRILAGFETPDTGRIVMQGRTLFdenSFVPAHLR-----RIGFVPQ 84
Cdd:COG4172   23 VEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLL---GLSERELRrirgnRIAMIFQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  85 E--GALFPHLNVADNIAWGLdgTRHEK------RQRVEALMEMVSLD--RQLATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:COG4172  100 EpmTSLNPLHTIGKQIAEVL--RLHRGlsgaaaRARALELLERVGIPdpERRLDAYPHQLSGGQRQRVMIAMALANEPDL 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:COG4172  178 LIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELFAAP 248
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
10-199 2.48e-33

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 121.96  E-value: 2.48e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdensfvpahlRRIGFVPQEGAL- 88
Cdd:NF040873   1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGG-------------ARVAYVPQRSEVp 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 --FPhLNVADNIAWGLDGTR-------HEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:NF040873  68 dsLP-LTVRDLVAMGRWARRglwrrltRDDRAAVDDALERVGLAD-LAGRQLGELSGGQRQRALLAQGLAQEADLLLLDE 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 697052228 160 PFSALDtglrAMTRKATADLLAEA---GVASILVTHDQNEALS 199
Cdd:NF040873 146 PTTGLD----AESRERIIALLAEEharGATVVVVTHDLELVRR 184
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
1-223 4.42e-33

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 123.20  E-value: 4.42e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHL-RRI 79
Cdd:PRK11231   2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPI---SMLSSRQLaRRL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQ-----EGALF---------PHLNVadniaWGLDGTrhEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALA 145
Cdd:PRK11231  79 ALLPQhhltpEGITVrelvaygrsPWLSL-----WGRLSA--EDNARVNQAMEQTRIN-HLADRRLTDLSGGQRQRAFLA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 146 RALAQRPSLMLLDEPFSALDTG----LRAMTRKatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:PRK11231 151 MVLAQDTPVVLLDEPTTYLDINhqveLMRLMRE-----LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEV 225


                 ..
gi 697052228 222 YT 223
Cdd:PRK11231 226 MT 227
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
2-238 5.06e-33

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 123.16  E-value: 5.06e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL------------FDEN 69
Cdd:PRK10619   6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqlkvADKN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  70 SFvpAHLR-RIGFVPQEGALFPHLNVADNIAWG----LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVAL 144
Cdd:PRK10619  86 QL--RLLRtRLTMVFQHFNLWSHMTVLENVMEApiqvLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRVSI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 145 ARALAQRPSLMLLDEPFSALDTG-----LRAMTRkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:PRK10619 164 ARALAMEPEVLLFDEPTSALDPElvgevLRIMQQ------LAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPE 237

                        250
                 ....*....|....*....
gi 697052228 220 DVYTRPVDEETALFLGDAV 238
Cdd:PRK10619 238 QLFGNPQSPRLQQFLKGSL 256
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-218 8.31e-33

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 122.95  E-value: 8.31e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlfdENsfVPAHLR--- 77
Cdd:PRK11831   7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDG-----EN--IPAMSRsrl 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 -----RIGFVPQEGALFPHLNVADNIAWGLdgtrHEKRQRVEAL--------MEMVSLdRQLATHWPHEISGGQQQRVAL 144
Cdd:PRK11831  80 ytvrkRMSMLFQSGALFTDMNVFDNVAYPL----REHTQLPAPLlhstvmmkLEAVGL-RGAAKLMPSELSGGMARRAAL 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 145 ARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:PRK11831 155 ARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSA 228
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 15-211 1.33e-32

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 122.22  E-value: 1.33e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDEN-SFVPAHLRRIGFVPQE--GALFPH 91
Cdd:TIGR02769  25 PVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDrKQRRAFRRDVQLVFQDspSAVNPR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   92 LNVADNIAWGLdgtRH-------EKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:TIGR02769 105 MTVRQIIGEPL---RHltsldesEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNL 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 697052228  165 DTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:TIGR02769 182 DMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQ 228
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-225 1.69e-32

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 124.95  E-value: 1.69e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdENSFVPAHLRRIG 80
Cdd:PRK09536   3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV--EALSARAASRRVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWG-------LDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK09536  81 SVPQDTSLSFEFDVRQVVEMGrtphrsrFDTWTETDRAAVERAMERTGVA-QFADRPVTSLSGGERQRVLLARALAQATP 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 154 LMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK09536 160 VLLLDEPTASLDINHQVRTLELVRR-LVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTAD 230
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
7-234 3.04e-32

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 124.38  E-value: 3.04e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQVLDSLNLS---------VAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLR 77
Cdd:PRK10070  25 IEQGLSKEQILEKTGLSlgvkdaslaIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDG---VDIAKISDAELR 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 -----RIGFVPQEGALFPHLNVADNIAWGLDGT---RHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALA 149
Cdd:PRK10070 102 evrrkKIAMVFQSFALMPHMTVLDNTAFGMELAginAEERREKALDALRQVGLE-NYAHSYPDELSGGMRQRVGLARALA 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 150 QRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEE 229
Cdd:PRK10070 181 INPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDY 260


                 ....*
gi 697052228 230 TALFL 234
Cdd:PRK10070 261 VRTFF 265
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 2-211 3.91e-32

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 119.24  E-value: 3.91e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtLFDENSFVPAH--LRRI 79
Cdd:cd03268    1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEI------TFDGKSYQKNIeaLRRI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHLNVADNIAWGLDGTRHEKrQRVEALMEMVSL----DRQLATHwpheiSGGQQQRVALARALAQRPSLM 155
Cdd:cd03268   75 GALIEAPGFYPNLTARENLRLLARLLGIRK-KRIDEVLDVVGLkdsaKKKVKGF-----SLGMKQRLGIALALLGNPDLL 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 156 LLDEPFSALDT-GLRAMtRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03268  149 ILDEPTNGLDPdGIKEL-RELILS-LRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 13-217 5.75e-32

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 119.57  E-value: 5.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-IGFVPQEGALFPh 91
Cdd:cd03249   15 DVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGV---DIRDLNLRWLRSqIGLVSQEPVLFD- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LNVADNIAWGLDGTRHEKRQRVEALME----MVSLDRQLATH-WPH--EISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:cd03249   91 GTIAENIRYGKPDATDEEVEEAAKKANihdfIMSLPDGYDTLvGERgsQLSGGQKQRIAIARALLRNPKILLLDEATSAL 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 165 DTglraMTRKATADLLAEA--GVASILVTHD----QNealsfATQVAVMRSGRFTQVGT 217
Cdd:cd03249  171 DA----ESEKLVQEALDRAmkGRTTIVIAHRlstiRN-----ADLIAVLQNGQVVEQGT 220
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 2-230 9.77e-32

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 119.63  E-value: 9.77e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDTGRIVMQGRTLFDENsfVPAHL 76
Cdd:PRK14247   4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMD--VIELR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPHLNVADNIAWGLD-----GTRHEKRQRVEALMEMVSL-----DRQLAThwPHEISGGQQQRVALAR 146
Cdd:PRK14247  82 RRVQMVFQIPNPIPNLSIFENVALGLKlnrlvKSKKELQERVRWALEKAQLwdevkDRLDAP--AGKLSGGQQQRLCIAR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 147 ALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:PRK14247 160 ALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTI--VLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPR 237


                 ....
gi 697052228 227 DEET 230
Cdd:PRK14247 238 HELT 241
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 21-235 1.27e-31

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 120.12  E-value: 1.27e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  21 NLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvPAHLRRI----GFVPQ--EGALFPHlNV 94
Cdd:PRK13634  27 NVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKK--NKKLKPLrkkvGIVFQfpEHQLFEE-TV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAM 171
Cdd:PRK13634 104 EKDICFGpmnFGVSEEDAKQKAREMIELVGLPEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKE 183

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 172 TRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPvDEETALFLG 235
Cdd:PRK13634 184 MMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADP-DELEAIGLD 246
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 11-218 1.46e-31

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 118.49  E-value: 1.46e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDV--------QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL--FDENSfvpahLRR-I 79
Cdd:cd03253    3 FENVtfaydpgrPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIreVTLDS-----LRRaI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFpHLNVADNIAWG-LDGTRHEKRQRVEA------LMEM------VSLDRQLathwphEISGGQQQRVALAR 146
Cdd:cd03253   78 GVVPQDTVLF-NDTIGYNIRYGrPDATDEEVIEAAKAaqihdkIMRFpdgydtIVGERGL------KLSGGEKQRVAIAR 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 147 ALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLaeAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTP 218
Cdd:cd03253  151 AILKNPPILLLDEATSALDTHTEREIQAALRDVS--KGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERGTH 219
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 16-211 2.82e-31

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 124.21  E-value: 2.82e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRR-IGFVPQEGALFpHLNV 94
Cdd:TIGR03375 480 ALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDG---VDIRQIDPADLRRnIGYVPQDPRLF-YGTL 555

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGldgTRHEKRQRVEALMEMVSLDRQLATHwPH-----------EISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:TIGR03375 556 RDNIALG---APYADDEEILRAAELAGVTEFVRRH-PDgldmqigergrSLSGGQRQAVALARALLRDPPILLLDEPTSA 631

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 697052228  164 LDTGLRAMTRKATADLLAEAGVasILVTHdQNEALSFATQVAVMRSGR 211
Cdd:TIGR03375 632 MDNRSEERFKDRLKRWLAGKTL--VLVTH-RTSLLDLVDRIIVMDNGR 676
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 10-221 4.64e-31

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 116.94  E-value: 4.64e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFS---DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLR-RIGFVPQE 85
Cdd:cd03254    9 NFSydeKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGI---DIRDISRKSLRsMIGVVLQD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 GALFPHlNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03254   86 TFLFSG-TIMENIRLGRPNATDEEVIEAAKEAGAHDFIMKLPNGYDTVLgenggnlSQGERQLLAIARAMLRDPKILILD 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 159 EPFSALDTGLRAMTRKATADLLaeAGVASILVTHdqneALS---FATQVAVMRSGRFTQVGTPYDV 221
Cdd:cd03254  165 EATSNIDTETEKLIQEALEKLM--KGRTSIIIAH----RLStikNADKILVLDDGKIIEEGTHDEL 224
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 1-211 5.03e-31

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 116.76  E-value: 5.03e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFS-------DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI-VMQGRTLFDENSFV 72
Cdd:COG4778    4 LLEVENLSKTFTlhlqggkRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSIlVRHDGGWVDLAQAS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  73 P---AHLRR--IGFVPQegalfpHLNV-----ADNI------AWGLDgtRHEKRQRVEALMEMVSLDRQLATHWPHEISG 136
Cdd:COG4778   84 PreiLALRRrtIGYVSQ------FLRViprvsALDVvaepllERGVD--REEARARARELLARLNLPERLWDLPPATFSG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 137 GQQQRVALARALAQRPSLMLLDEPFSALDtglrAMTRKATADLLAEA---GVASILVTHDQN--EALsfATQVAVMRSGR 211
Cdd:COG4778  156 GEQQRVNIARGFIADPPLLLLDEPTASLD----AANRAVVVELIEEAkarGTAIIGIFHDEEvrEAV--ADRVVDVTPFS 229
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 1-226 5.04e-31

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 117.49  E-value: 5.04e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAhlRRIG 80
Cdd:COG4604    1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELA--KRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGAL--------------FPH----LNVADniawgldgtrHEKRQRVEALMEMVSL-DRQLathwpHEISGGQQQR 141
Cdd:COG4604   79 ILRQENHInsrltvrelvafgrFPYskgrLTAED----------REIIDEAIAYLDLEDLaDRYL-----DELSGGQRQR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 142 VALARALAQRPSLMLLDEPFSALD----TGLRAMTRKATADLlaeaGVASILVTHDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:COG4604  144 AFIAMVLAQDTDYVLLDEPLNNLDmkhsVQMMKLLRRLADEL----GKTVVIVLHDINFASCYADHIVAMKDGRVVAQGT 219


                 ....*....
gi 697052228 218 PYDVYTRPV 226
Cdd:COG4604  220 PEEIITPEV 228
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 1-197 6.92e-31

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 116.42  E-value: 6.92e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:PRK10584   6 IVEVHHLKKSVgqgeHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 R--RIGFVPQEGALFPHLNVADNIAWG--LDGTR-HEKRQRVEALMEMVSLDRQLaTHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK10584  86 RakHVGFVFQSFMLIPTLNALENVELPalLRGESsRQSRNGAKALLEQLGLGKRL-DHLPAQLSGGEQQRVALARAFNGR 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697052228 152 PSLMLLDEPFSALD--TGLRamtrkaTADLL----AEAGVASILVTHDQNEA 197
Cdd:PRK10584 165 PDVLFADEPTGNLDrqTGDK------IADLLfslnREHGTTLILVTHDLQLA 210
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 12-221 1.26e-30

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 121.78  E-value: 1.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHL-RRIGFVPQEGALFP 90
Cdd:COG4618  343 SKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWD---REELgRHIGYLPQDVELFD 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HlNVADNIAwgldgtRHEK---RQRVEALM-----EMV-SL----DRQLATHwPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:COG4618  420 G-TIAENIA------RFGDadpEKVVAAAKlagvhEMIlRLpdgyDTRIGEG-GARLSGGQRQRIGLARALYGDPRLVVL 491

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 158 DEPFSALDT-GLRAMTRkaTADLLAEAGVASILVTHDQNeALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:COG4618  492 DEPNSNLDDeGEAALAA--AIRALKARGATVVVITHRPS-LLAAVDKLLVLRDGRVQAFGPRDEV 553
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-221 2.17e-30

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 115.76  E-value: 2.17e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTA--ISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlfDENSFVPAH--- 75
Cdd:PRK10895   1 MATLTAknLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDD----EDISLLPLHara 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 LRRIGFVPQEGALFPHLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQR 151
Cdd:PRK10895  77 RRGIGYLPQEASIFRRLSVYDNLMAVLqirdDLSAEQREDRANELMEEFHIE-HLRDSMGQSLSGGERRRVEIARALAAN 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 152 PSLMLLDEPFSALDTgLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:PRK10895 156 PKFILLDEPFAGVDP-ISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEI 224
cbiO PRK13637
energy-coupling factor transporter ATPase;
17-222 4.70e-30

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 115.92  E-value: 4.70e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGFVPQ--EGALFPHlNV 94
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIRKKVGLVFQypEYQLFEE-TI 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQ-LATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:PRK13637 102 EKDIAFGpinLGLSEEEIENRVKRAMNIVGLDYEdYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRD 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697052228 171 MTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13637 182 EILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 8-211 7.39e-30

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 112.95  E-value: 7.39e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   8 SKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdensfvpahlrrIGFVPQEGA 87
Cdd:cd03250   12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS---------------IAYVSQEPW 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  88 LfphLN--VADNIAWGLdgtRHEKrQRVEALMEMVSLDRQLAThWPH----EI-------SGGQQQRVALARALAQRPSL 154
Cdd:cd03250   77 I---QNgtIRENILFGK---PFDE-ERYEKVIKACALEPDLEI-LPDgdltEIgekginlSGGQKQRISLARAVYSDADI 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 155 MLLDEPFSALD--TGLRAMTRKATADLLAEAGVasILVTHdQNEALSFATQVAVMRSGR 211
Cdd:cd03250  149 YLLDDPLSAVDahVGRHIFENCILGLLLNNKTR--ILVTH-QLQLLPHADQIVVLDNGR 204
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 1-210 4.54e-29

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 117.07  E-value: 4.54e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfVPAHLRRIG 80
Cdd:PRK15439  11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTP-AKAHQLGIY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLdgTRHEKR-QRVEALMemvsldRQLATHWPHEISGG-----QQQRVALARALAQRPSL 154
Cdd:PRK15439  90 LVPQEPLLFPNLSVKENILFGL--PKRQASmQKMKQLL------AALGCQLDLDSSAGslevaDRQIVEILRGLMRDSRI 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 155 MLLDEPFSALDTG-LRAMTRKATAdLLAEaGVASILVTHDQNEALSFATQVAVMRSG 210
Cdd:PRK15439 162 LILDEPTASLTPAeTERLFSRIRE-LLAQ-GVGIVFISHKLPEIRQLADRISVMRDG 216
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-193 5.42e-29

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 117.52  E-value: 5.42e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:PRK10535   4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RR--IGFVPQEGALFPHLNVADNI---AWGLDGTRHEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQR 151
Cdd:PRK10535  84 RRehFGFIFQRYHLLSHLTAAQNVevpAVYAGLERKQRLLRAQELLQRLGLEDRVEYQ-PSQLSGGQQQRVSIARALMNG 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 697052228 152 PSLMLLDEPFSALD--TGLRAMtrkATADLLAEAGVASILVTHD 193
Cdd:PRK10535 163 GQVILADEPTGALDshSGEEVM---AILHQLRDRGHTVIIVTHD 203
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-217 6.75e-29

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 116.57  E-value: 6.75e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTgrivMQGRTLFDENSFVPAHLRR-- 78
Cdd:PRK13549   5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGT----YEGEIIFEGEELQASNIRDte 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 ---IGFVPQEGALFPHLNVADNIAWGLDGTRH------EKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALA 149
Cdd:PRK13549  81 ragIAIIHQELALVKELSVLENIFLGNEITPGgimdydAMYLRAQKLLAQLKLDINPATP-VGNLGLGQQQLVEIAKALN 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 150 QRPSLMLLDEPFSALdtglramTRKATADLLA------EAGVASILVTHDQNEALSFATQVAVMRSGRFtqVGT 217
Cdd:PRK13549 160 KQARLLILDEPTASL-------TESETAVLLDiirdlkAHGIACIYISHKLNEVKAISDTICVIRDGRH--IGT 224
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 15-224 7.04e-29

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 116.73  E-value: 7.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTT----LLRILAGfetpdTGRIVMQGRTL--FDENSFVPAHlRRIGFVPQE--G 86
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLhnLNRRQLLPVR-HRIQVVFQDpnS 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 ALFPHLNVADNIAWGL-----DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:PRK15134 374 SLNPRLNVLQIIEEGLrvhqpTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPT 453

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 162 SALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG-------TPYDVYTR 224
Cdd:PRK15134 454 SSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGdcervfaAPQQEYTR 523
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 18-225 7.87e-29

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 113.65  E-value: 7.87e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  18 DSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQE--GALFPHLNV 94
Cdd:PRK15079  38 DGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSdIQMIFQDplASLNPRMTI 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGL-----DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLR 169
Cdd:PRK15079 118 GEIIAEPLrtyhpKLSRQEVKDRVKAMMLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQ 197

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 170 AMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK15079 198 AQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 1-223 9.18e-29

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 112.01  E-value: 9.18e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF--SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFvpaHLR- 77
Cdd:PRK13632   7 MIKVENVSFSYpnSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLK---EIRk 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQE-GALFPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRQLaTHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK13632  84 KIGIIFQNpDNQFIGATVEDDIAFGLENkkvPPKKMKDIIDDLAKKVGMEDYL-DKEPQNLSGGQKQRVAIASVLALNPE 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 154 LMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:PRK13632 163 IIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEILN 231
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-226 1.27e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 112.59  E-value: 1.27e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHLR---- 77
Cdd:PRK13537   8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEP-------VPSRARharq 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQEGALFPHLNVADNIA-----WGLdgTRHEKRQRVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRP 152
Cdd:PRK13537  81 RVGVVPQFDNLDPDFTVRENLLvfgryFGL--SAAAARALVPPLLEFAKLENK-ADAKVGELSGGMKRRLTLARALVNDP 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAeAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:PRK13537 158 DVLVLDEPTTGLDPQARHLMWERLRSLLA-RGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIESEI 230
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 12-234 1.55e-28

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 111.29  E-value: 1.55e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-ETPDT-----GRIVMQGRTLFDENSFvpaHLRR-IGFVPQ 84
Cdd:PRK14246  21 NDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLiEIYDSkikvdGKVLYFGKDIFQIDAI---KLRKeVGMVFQ 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  85 EGALFPHLNVADNIAWGLDG----TRHEKRQRVEALMEMVSLDRQLATHW---PHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK14246  98 QPNPFPHLSIYDNIAYPLKShgikEKREIKKIVEECLRKVGLWKEVYDRLnspASQLSGGQQQRLTIARALALKPKVLLM 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEagVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:PRK14246 178 DEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 17-222 2.85e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 110.61  E-value: 2.85e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvpAHLRR-IGFVPQEGA-LFPHLNV 94
Cdd:PRK13648  25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNF---EKLRKhIGIVFQNPDnQFVGSIV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGLDG--TRHEKRQRV--EALMEMVSLDRqlATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:PRK13648 102 KYDVAFGLENhaVPYDEMHRRvsEALKQVDMLER--ADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQ 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697052228 171 MTRKATADLLAEAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13648 180 NLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIF 230
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 1-216 2.86e-28

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 110.40  E-value: 2.86e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIV--MQGRTLFDENSFVPAHLRR 78
Cdd:PRK11701   6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHyrMRDGQLRDLYALSEAERRR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 I-----GFVPQEGA--LFPHLNVADNIAWGL--DGTRHEKRQRVEAL--MEMVSLDRQLATHWPHEISGGQQQRVALARA 147
Cdd:PRK11701  86 LlrtewGFVHQHPRdgLRMQVSAGGNIGERLmaVGARHYGDIRATAGdwLERVEIDAARIDDLPTTFSGGMQQRLQIARN 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 148 LAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:PRK11701 166 LVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 8-211 2.90e-28

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 108.41  E-value: 2.90e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   8 SKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG--FETPDTGRIVMQGRTLfDENSFVpahlRRIGFVPQE 85
Cdd:cd03213   16 SPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPL-DKRSFR----KIIGYVPQD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 GALFPHLNVadniawgldgtrhekrqrVEALMEMVSLDRqlathwpheISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03213   91 DILHPTLTV------------------RETLMFAAKLRG---------LSGGERKRVSIALELVSNPSLLFLDEPTSGLD 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697052228 166 TG-----LRAMTRkatadlLAEAGVASILVTHD-QNEALSFATQVAVMRSGR 211
Cdd:cd03213  144 SSsalqvMSLLRR------LADTGRTIICSIHQpSSEIFELFDKLLLLSQGR 189
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 16-217 3.09e-28

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 109.63  E-value: 3.09e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensFVPAHLRR-IGFVPQEGALFpHLNV 94
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRD---YTLASLRRqIGLVSQDVFLF-NDTV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGLDG-TRHEKRQRVEA--LMEMV-SLDRQLAThwphEI-------SGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03251   93 AENIAYGRPGaTREEVEEAARAanAHEFImELPEGYDT----VIgergvklSGGQRQRIAIARALLKDPPILILDEATSA 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 164 LDTGLRAMTRKATADLLaeAGVASILVTHdqneALSF---ATQVAVMRSGRFTQVGT 217
Cdd:cd03251  169 LDTESERLVQAALERLM--KNRTTFVIAH----RLSTienADRIVVLEDGKIVERGT 219
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-221 3.57e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 111.85  E-value: 3.57e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHLR---- 77
Cdd:PRK13536  42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVP-------VPARARlara 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQEGALFPHLNVADNIA-----WGLDgTRhEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQRP 152
Cdd:PRK13536 115 RIGVVPQFDNLDLEFTVRENLLvfgryFGMS-TR-EIEAVIPSLLEFARLESKADAR-VSDLSGGMKRRLTLARALINDP 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEaGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:PRK13536 192 QLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHAL 259
CP_lyasePhnK TIGR02323
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ...
 1-216 3.73e-28

phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]


Pssm-ID: 188208 [Multi-domain]  Cd Length: 253  Bit Score: 109.92  E-value: 3.73e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI--VMQGRTLFDENSFVPAHLRR 78
Cdd:TIGR02323   3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTAtyIMRSGAELELYQLSEAERRR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   79 I-----GFVPQEGA--LFPHLNVADNIAWGL--DGTRHEKRQRVEAL--MEMVSLDRQLATHWPHEISGGQQQRVALARA 147
Cdd:TIGR02323  83 LmrtewGFVHQNPRdgLRMRVSAGANIGERLmaIGARHYGNIRATAQdwLEEVEIDPTRIDDLPRAFSGGMQQRLQIARN 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  148 LAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:TIGR02323 163 LVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESG 231
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 13-263 4.32e-28

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 110.21  E-value: 4.32e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFvpaHLR-RIGFVPQ--EGALF 89
Cdd:PRK13647  17 GTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEK---WVRsKVGLVFQdpDDQVF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PhLNVADNIAWG---LDGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK13647  94 S-STVWDDVAFGpvnMGLDKDEVERRVEEALKAVRM-WDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDP 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 167 GLRAmTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLGdaviLPAQLAA 246
Cdd:PRK13647 172 RGQE-TLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDEDIVEQAGLRLP----LVAQIFE 246

                        250
                 ....*....|....*..
gi 697052228 247 GYAVCALGEVPTDNAQA 263
Cdd:PRK13647 247 DLPELGQSKLPLTVKEA 263
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 1-230 1.08e-27

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 109.40  E-value: 1.08e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD-VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FDENSFVPAHlRR 78
Cdd:PRK13639   1 ILETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkYDKKSLLEVR-KT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQ--EGALF-PhlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRP 152
Cdd:PRK13639  80 VGIVFQnpDDQLFaP--TVEEDVAFGplnLGLSKEEVEKRVKEALKAVGME-GFENKPPHHLSGGQKKRVAIAGILAMKP 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEaGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTrpvDEET 230
Cdd:PRK13639 157 EIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFS---DIET 230
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 16-217 1.09e-27

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 108.34  E-value: 1.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRR-IGFVPQEGALFpHLNV 94
Cdd:cd03252   17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDG---HDLALADPAWLRRqVGVVLQENVLF-NRSI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGLDGTRHEKRQRV-------EALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:cd03252   93 RDNIALADPGMSMERVIEAaklagahDFISELPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIFDEATSALDYE 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 697052228 168 LRAMTRKATADLLaeAGVASILVTHdQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:cd03252  173 SEHAIMRNMHDIC--AGRTVIIIAH-RLSTVKNADRIIVMEKGRIVEQGS 219
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 16-192 2.02e-27

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 112.59  E-value: 2.02e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqgrtlfdensfvPAHlRRIGFVPQEgALFPHLNVA 95
Cdd:COG4178  378 LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR------------PAG-ARVLFLPQR-PYLPLGTLR 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWGLDGTRHEkRQRVEALMEMVSLDRqLATH------WPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLR 169
Cdd:COG4178  444 EALLYPATAEAFS-DAELREALEAVGLGH-LAERldeeadWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENE 521

                        170       180
                 ....*....|....*....|...
gi 697052228 170 AMTRKATADLLAEAGVasILVTH 192
Cdd:COG4178  522 AALYQLLREELPGTTV--ISVGH 542
cbiO PRK13649
energy-coupling factor transporter ATPase;
17-222 2.06e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 108.68  E-value: 2.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR--TLFDENSFVPAHLRRIGFVPQ--EGALFPHl 92
Cdd:PRK13649  23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTliTSTSKNKDIKQIRKKVGLVFQfpESQLFEE- 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  93 NVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglr 169
Cdd:PRK13649 102 TVLKDVAFGPQNfgvSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLD---- 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 170 AMTRKATADL---LAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13649 178 PKGRKELMTLfkkLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
cbiO PRK13650
energy-coupling factor transporter ATPase;
17-224 2.77e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 108.28  E-value: 2.77e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQE------GAlfp 90
Cdd:PRK13650  23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEEN--VWDIRHKIGMVFQNpdnqfvGA--- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 hlNVADNIAWGLD--GTRHEK-RQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG 167
Cdd:PRK13650  98 --TVEDDVAFGLEnkGIPHEEmKERVNEALELVGM-QDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPE 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 168 LRAMTRKATADLLAEAGVASILVTHDQNE-ALSfaTQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:PRK13650 175 GRLELIKTIKGIRDDYQMTVISITHDLDEvALS--DRVLVMKNGQVESTSTPRELFSR 230
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 1-217 2.90e-27

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 111.84  E-value: 2.90e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTgrivMQGRTLFDENSFVPAHLRR-- 78
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGT----WDGEIYWSGSPLKASNIRDte 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   79 ---IGFVPQEGALFPHLNVADNIAWG----LDGTR---HEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARAL 148
Cdd:TIGR02633  77 ragIVIIHQELTLVPELSVAENIFLGneitLPGGRmayNAMYLRAKNLLRELQLDADNVTRPVGDYGGGQQQLVEIAKAL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228  149 AQRPSLMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRftQVGT 217
Cdd:TIGR02633 157 NKQARLLILDEPSSSL-------TEKETEILldiirdLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ--HVAT 222
cbiO PRK13641
energy-coupling factor transporter ATPase;
15-225 3.04e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 108.38  E-value: 3.04e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDE--NSFVPAHLRRIGFVPQ--EGALFP 90
Cdd:PRK13641  21 KGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPEtgNKNLKKLRKKVSLVFQfpEAQLFE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtg 167
Cdd:PRK13641 101 N-TVLKDVEFGpknFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLD-- 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 168 lrAMTRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK13641 178 --PEGRKEMMQLFKDyqkAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 14-221 3.84e-27

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 111.43  E-value: 3.84e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI-VMQGRTLFDENSFVPAHLRR----IGFVPQEGAL 88
Cdd:TIGR03269 297 VKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDEWVDMTKPGPDGRGRakryIGILHQEYDL 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   89 FPHLNVADNI--AWGLDGTRHEKRQRVEALMEMVSLDRQLATH----WPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:TIGR03269 377 YPHRTVLDNLteAIGLELPDELARMKAVITLKMVGFDEEKAEEildkYPDELSEGERHRVALAQVLIKEPRIVILDEPTG 456

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  163 ALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:TIGR03269 457 TMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPEEI 515
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 1-211 5.81e-27

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 107.09  E-value: 5.81e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF-----SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAH 75
Cdd:COG1101    1 MLELKNLSKTFnpgtvNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV----TKLPEY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 LR--RIGFV---PQEGAlFPHLNVADNIA------------WGLDGTRHEK-RQRVEALmEMvSLDRQLAThwphEI--- 134
Cdd:COG1101   77 KRakYIGRVfqdPMMGT-APSMTIEENLAlayrrgkrrglrRGLTKKRRELfRELLATL-GL-GLENRLDT----KVgll 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 135 SGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:COG1101  150 SGGQRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGR 226
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 10-225 6.93e-27

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 111.35  E-value: 6.93e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   10 SFS-----DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL--FDENSFvpaHlRRIGFV 82
Cdd:TIGR00958 485 SFSypnrpDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLvqYDHHYL---H-RQVALV 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   83 PQEGALFPHlNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEI-------SGGQQQRVALARALAQRPSLM 155
Cdd:TIGR00958 561 GQEPVLFSG-SVRENIAYGLTDTPDEEIMAAAKAANAHDFIMEFPNGYDTEVgekgsqlSGGQKQRIAIARALVRKPRVL 639

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228  156 LLDEPFSALDtglrAMTRKATADLLAEAGVASILVTHDqneaLSF---ATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:TIGR00958 640 ILDEATSALD----AECEQLLQESRSRASRTVLLIAHR----LSTverADQILVLKKGSVVEMGTHKQLMEDQ 704
cbiO PRK13640
energy-coupling factor transporter ATPase;
12-226 7.65e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 107.19  E-value: 7.65e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDT---GRIVMQGRTLFDENSFvpaHLR-RIGFVPQE-G 86
Cdd:PRK13640  18 SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnSKITVDGITLTAKTVW---DIReKVGIVFQNpD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 ALFPHLNVADNIAWGLD--GTRHEKRQRV--EALMEMVSLDRQLAThwPHEISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK13640  95 NQFVGATVGDDVAFGLEnrAVPRPEMIKIvrDVLADVGMLDYIDSE--PANLSGGQKQRVAIAGILAVEPKIIILDESTS 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 163 ALDTGLRAMTRKATADLLAEAGVASILVTHDQNEAlSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:PRK13640 173 MLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEIFSKVE 235
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 8-244 1.00e-26

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 107.48  E-value: 1.00e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   8 SKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI----------------------VMQGRTL 65
Cdd:PRK13651  14 KKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkktkekekvlekLVIQKTR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  66 FDENSFVPAHLRRIGFVPQ--EGALFPHlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQ 140
Cdd:PRK13651  94 FKKIKKIKEIRRRVGVVFQfaEYQLFEQ-TIEKDIIFGpvsMGVSKEEAKKRAAKYIELVGLDESYLQRSPFELSGGQKR 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 141 RVALARALAQRPSLMLLDEPFSALD-TGLRAMTRkaTADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:PRK13651 173 RVALAGILAMEPDFLVFDEPTAGLDpQGVKEILE--IFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKIIKDGDTY 250

                        250       260
                 ....*....|....*....|....*
gi 697052228 220 DVYTrpvDEEtalFLGDAVILPAQL 244
Cdd:PRK13651 251 DILS---DNK---FLIENNMEPPKL 269
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-229 1.21e-26

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 109.88  E-value: 1.21e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG------FEtpdtGRIVMQGRtlfdensfvPA 74
Cdd:NF040905   1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyphgsYE----GEILFDGE---------VC 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRRI------GFV--PQEGALFPHLNVADNIAWGLDGTR------HEKRQRVEALMEMVSLDRQLATHWPHeISGGQQQ 140
Cdd:NF040905  68 RFKDIrdsealGIViiHQELALIPYLSIAENIFLGNERAKrgvidwNETNRRARELLAKVGLDESPDTLVTD-IGVGKQQ 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 141 RVALARALAQRPSLMLLDEPFSAL---DTglramtrKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRftQ 214
Cdd:NF040905 147 LVEIAKALSKDVKLLILDEPTAALneeDS-------AALLDLLLElkaQGITSIIISHKLNEIRRVADSITVLRDGR--T 217

                        250
                 ....*....|....*
gi 697052228 215 VGTpYDVYTRPVDEE 229
Cdd:NF040905 218 IET-LDCRADEVTED 231
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 13-217 2.84e-26

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 109.42  E-value: 2.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensFVPAHLRR-IGFVPQEGALFPH 91
Cdd:TIGR02203 344 DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLAD---YTLASLRRqVALVSQDVVLFND 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   92 lNVADNIAWGldGTRHEKRQRVEALMEMVSL----DR-QLATHWP-----HEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:TIGR02203 421 -TIANNIAYG--RTEQADRAEIERALAAAYAqdfvDKlPLGLDTPigengVLLSGGQRQRLAIARALLKDAPILILDEAT 497

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228  162 SALDTGLRAMTRKATADLLaeAGVASILVTHdQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:TIGR02203 498 SALDNESERLVQAALERLM--QGRTTLVIAH-RLSTIEKADRIVVMDDGRIVERGT 550
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 1-212 3.68e-26

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 102.51  E-value: 3.68e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAIS--KSFSDVqvldslNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR 78
Cdd:cd03215    4 VLEVRGLSvkGAVRDV------SFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPV---TRRSPRDAIR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 --IGFVP---QEGALFPHLNVADNIAwgldgtrhekrqrvealmemvsLDRQLathwpheiSGGQQQRVALARALAQRPS 153
Cdd:cd03215   75 agIAYVPedrKREGLVLDLSVAENIA----------------------LSSLL--------SGGNQQKVVLARWLARDPR 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 154 LMLLDEPFSALDTGlramtrkATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRF 212
Cdd:cd03215  125 VLILDEPTRGVDVG-------AKAEIyrlireLADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
16-223 5.98e-26

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 104.30  E-value: 5.98e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAhlRRIGFVPQEGALFPHLNVA 95
Cdd:PRK10253  22 VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA--RRIGLLAQNATTPGDITVQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWG-------LDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL 168
Cdd:PRK10253 100 ELVARGryphqplFTRWRKEDEEAVTKAMQATGIT-HLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISH 178

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 169 RAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:PRK10253 179 QIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVT 233
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
1-210 1.07e-25

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 103.55  E-value: 1.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDT---GRIVMQGRTLFDENSF---VPA 74
Cdd:PRK09984   4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKsagSHIELLGRTVQREGRLardIRK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRRIGFVPQEGALFPHLNVADNIAWGLDG------------TRHEKRQRVEALMemvsldRQLATHWPHE----ISGGQ 138
Cdd:PRK09984  84 SRANTGYIFQQFNLVNRLSVLENVLIGALGstpfwrtcfswfTREQKQRALQALT------RVGMVHFAHQrvstLSGGQ 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 139 QQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSG 210
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQG 229
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 13-192 1.22e-25

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 101.87  E-value: 1.22e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlfdENSFVPAHLRRIGFVPQEGALFPHL 92
Cdd:PRK13539  14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDG-----GDIDDPDVAEACHYLGHRNAMKPAL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  93 NVADNIA-W-GLDGTRhekRQRVEALMEMVSLdrQLATHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLR 169
Cdd:PRK13539  89 TVAENLEfWaAFLGGE---ELDIAAALEAVGL--APLAHLPfGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAV 163

                        170       180
                 ....*....|....*....|...
gi 697052228 170 AMTRKATADLLAEAGVAsILVTH 192
Cdd:PRK13539 164 ALFAELIRAHLAQGGIV-IAATH 185
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 12-225 1.49e-25

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 103.73  E-value: 1.49e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFV---PQEGAL 88
Cdd:PRK13652  15 GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKEN--IREVRKFVGLVfqnPDDQIF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FPhlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13652  93 SP--TVEQDIAFGpinLGLDEETVAHRVSSALHMLGLE-ELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 166 TGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK13652 170 PQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 1-196 1.64e-25

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 102.10  E-value: 1.64e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-I 79
Cdd:PRK10247   7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGE---DISTLKPEIYRQqV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPHlNVADNIA--WGLDGTRHEkRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK10247  84 SYCAQTPTLFGD-TVYDNLIfpWQIRNQQPD-PAIFLDDLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLL 161

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNE 196
Cdd:PRK10247 162 DEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDE 200
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
1-230 1.72e-25

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 103.33  E-value: 1.72e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF---------SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FDENS 70
Cdd:PRK15112   4 LLEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLhFGDYS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  71 FVPAHLRRIgFVPQEGALFPHLNVADNIAWGL----DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALAR 146
Cdd:PRK15112  84 YRSQRIRMI-FQDPSTSLNPRQRISQILDFPLrlntDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGLAR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 147 ALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:PRK15112 163 ALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPL 242


                 ....
gi 697052228 227 DEET 230
Cdd:PRK15112 243 HELT 246
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 2-205 2.43e-25

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 99.06  E-value: 2.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGrIVMQGRTLfdensfvpahlrRIGF 81
Cdd:cd03221    1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEG-IVTWGSTV------------KIGY 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQegalfphlnvadniawgldgtrhekrqrvealmemvsldrqlathwpheISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03221   68 FEQ-------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPT 98

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 697052228 162 SALDTGlramTRKATADLLAEAGVASILVTHDQnealSFATQVA 205
Cdd:cd03221   99 NHLDLE----SIEALEEALKEYPGTVILVSHDR----YFLDQVA 134
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 12-211 2.47e-25

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 101.78  E-value: 2.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVpaHlRRIGFVPQEGALFP 90
Cdd:cd03248   25 PDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQyEHKYL--H-SKVSLVGQEPVLFA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HlNVADNIAWGLDGTRHEK----RQRVEA---LMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03248  102 R-SLQDNIAYGLQSCSFECvkeaAQKAHAhsfISELASGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSA 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 697052228 164 LDTGLRAMTRKATADLLAEAGVasILVTHDQNeALSFATQVAVMRSGR 211
Cdd:cd03248  181 LDAESEQQVQQALYDWPERRTV--LVIAHRLS-TVERADQILVLDGGR 225
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 10-217 2.48e-25

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 106.47  E-value: 2.48e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRIVMQGRTLfdeNSFVPAHLRR-IGFVPQEGAL 88
Cdd:PRK11174 359 SPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINGIEL---RELDPESWRKhLSWVGQNPQL 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FpHLNVADNIawgLDGTRHEKRQRVEALMEMVSLD---RQLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK11174 435 P-HGTLRDNV---LLGNPDASDEQLQQALENAWVSeflPLLPQGLDTPIgdqaaglSVGQAQRLALARALLQPCQLLLLD 510

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 159 EPFSALD--------TGLRAMTRKATAdllaeagvasILVTHdQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:PRK11174 511 EPTASLDahseqlvmQALNAASRRQTT----------LMVTH-QLEDLAQWDQIWVMQDGQIVQQGD 566
cbiO PRK13645
energy-coupling factor transporter ATPase;
5-223 2.78e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 103.16  E-value: 2.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   5 TAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQgrtlfdeNSFVPAHLRRI----- 79
Cdd:PRK13645  15 TYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVG-------DYAIPANLKKIkevkr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 -----GFVPQ--EGALFPHlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALA 149
Cdd:PRK13645  88 lrkeiGLVFQfpEYQLFQE-TIEKDIAFGpvnLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIA 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 150 QRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:PRK13645 167 MDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFS 240
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 15-166 3.04e-25

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 106.44  E-value: 3.04e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-IGFVPQEGALFphlN 93
Cdd:COG5265  372 PILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQ---DIRDVTQASLRAaIGIVPQDTVLF---N 445

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  94 --VADNIAWG-LDGTRHEkrqrVEALMEMVSLD----------------RQLathwphEISGGQQQRVALARALAQRPSL 154
Cdd:COG5265  446 dtIAYNIAYGrPDASEEE----VEAAARAAQIHdfieslpdgydtrvgeRGL------KLSGGEKQRVAIARTLLKNPPI 515

                        170
                 ....*....|..
gi 697052228 155 MLLDEPFSALDT 166
Cdd:COG5265  516 LIFDEATSALDS 527
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 11-211 3.30e-25

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 101.64  E-value: 3.30e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRRIGFV-PQEGALF 89
Cdd:cd03267   31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRR---KKFLRRIGVVfGQKTQLW 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHLNVADNIA-----WGLDGTRHekRQRVEALMEMVSLDRQLAThwP-HEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03267  108 WDLPVIDSFYllaaiYDLPPARF--KKRLDELSELLDLEELLDT--PvRQLSLGQRMRAEIAAALLHEPEILFLDEPTIG 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 697052228 164 LDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:cd03267  184 LDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGR 231
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 1-230 3.97e-25

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 101.78  E-value: 3.97e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDTGRIVMQGRTLFDENSFVPAH 75
Cdd:PRK14239   5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIYSPRTDTVDL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 LRRIGFVPQEGALFPhLNVADNIAWGLdgtRHEKRQRVEALMEMVSLDRQLATHWP------HE----ISGGQQQRVALA 145
Cdd:PRK14239  85 RKEIGMVFQQPNPFP-MSIYENVVYGL---RLKGIKDKQVLDEAVEKSLKGASIWDevkdrlHDsalgLSGGQQQRVCIA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 146 RALAQRPSLMLLDEPFSALDTgLRAMTRKATADLLAEAgVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDP-ISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNP 238


                 ....*
gi 697052228 226 VDEET 230
Cdd:PRK14239 239 KHKET 243
cbiO PRK13642
energy-coupling factor transporter ATPase;
12-227 4.68e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 102.09  E-value: 4.68e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFvpaHLRR-IGFVPQE-GALF 89
Cdd:PRK13642  18 SDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVW---NLRRkIGMVFQNpDNQF 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHLNVADNIAWGLDGT---RHEKRQRV-EALMEMVSLDrqLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13642  95 VGATVEDDVAFGMENQgipREEMIKRVdEALLAVNMLD--FKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLD 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 166 TGLRAMTRKATADLLAEAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVYTRPVD 227
Cdd:PRK13642 173 PTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSED 233
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 11-238 6.26e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 101.46  E-value: 6.26e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDTGRIVMQGRTLFDENsFVPAHLRR-IGFVPQ 84
Cdd:PRK14267  14 YGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPD-VDPIEVRReVGMVFQ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  85 EGALFPHLNVADNIAWGLD-----GTRHEKRQRVEALMEMVSL-----DRqlATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK14267  93 YPNPFPHLTIYDNVAIGVKlnglvKSKKELDERVEWALKKAALwdevkDR--LNDYPSNLSGGQRQRLVIARALAMKPKI 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL 234
Cdd:PRK14267 171 LLMDEPTANIDPVGTAKIEELLFELKKEYTI--VLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHELTEKYV 248


                 ....
gi 697052228 235 GDAV 238
Cdd:PRK14267 249 TGAL 252
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
1-213 8.54e-25

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 100.33  E-value: 8.54e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSF-SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFD-ENSFVPAHLRR 78
Cdd:PRK10908   1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlKNREVPFLRRQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAWGL---DGTRHEKRQRVEALMEMVSL-DRqlATHWPHEISGGQQQRVALARALAQRPSL 154
Cdd:PRK10908  81 IGMIFQDHHLLMDRTVYDNVAIPLiiaGASGDDIRRRVSAALDKVGLlDK--AKNFPIQLSGGEQQRVGIARAVVNKPAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 155 MLLDEPFSALDTGLramtRKATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRFT 213
Cdd:PRK10908 159 LLADEPTGNLDDAL----SEGILRLFEEfnrVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 9-221 1.13e-24

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 100.16  E-value: 1.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   9 KSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRT--LFDENSfvpahlrriGFVPQeg 86
Cdd:COG1134   34 TRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGRVsaLLELGA---------GFHPE-- 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 alfphLNVADNI-----AWGLdgTRHEKRQRVEalmEMVS-------LDRQLAThwpheISGGQQQRVALARALAQRPSL 154
Cdd:COG1134  103 -----LTGRENIylngrLLGL--SRKEIDEKFD---EIVEfaelgdfIDQPVKT-----YSSGMRARLAFAVATAVDPDI 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 155 MLLDEpfsALDTGLRAMTRKATADL--LAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:COG1134  168 LLVDE---VLAVGDAAFQKKCLARIreLRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEV 233
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 12-250 1.33e-24

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 100.30  E-value: 1.33e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQV---LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRIVMQGRTLfdeNSFVPAHLRRI-GFVPQEGA 87
Cdd:COG4138    4 NDVAVagrLGPISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPL---SDWSAAELARHrAYLSQQQS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  88 LFPHLNVADNIAWGLDGTRHEkrQRVEALMEMVSLDRQLAT--HWP-HEISGGQQQRVALARALAQ-------RPSLMLL 157
Cdd:COG4138   80 PPFAMPVFQYLALHQPAGASS--EAVEQLLAQLAEALGLEDklSRPlTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAmtrkATADLLAE---AGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTrpvdeetalfl 234
Cdd:COG4138  158 DEPMNSLDVAQQA----ALDRLLRElcqQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMT----------- 222

                        250
                 ....*....|....*.
gi 697052228 235 gdavilPAQLAAGYAV 250
Cdd:COG4138  223 ------PENLSEVFGV 232
cbiO PRK13643
energy-coupling factor transporter ATPase;
15-222 1.42e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 101.35  E-value: 1.42e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQG---RTLFDENSFVPAHlRRIGFVPQ--EGALF 89
Cdd:PRK13643  20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDivvSSTSKQKEIKPVR-KKVGVVFQfpESQLF 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHlNVADNIAWGLD--GTRHEKRQRVEA-LMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK13643  99 EE-TVLKDVAFGPQnfGIPKEKAEKIAAeKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDP 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 167 GLRAMTRKaTADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13643 178 KARIEMMQ-LFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVF 232
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 7-235 1.61e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 100.94  E-value: 1.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRIL-------AGFETpdTGRIVMQGRTLFDENSfVPAHLRRI 79
Cdd:PRK14271  27 LTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLnrmndkvSGYRY--SGDVLLGGRSIFNYRD-VLEFRRRV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGALFPhLNVADNIAWGLDG----TRHEKRQRVEALMEMVSL-----DRqlATHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK14271 104 GMLFQRPNPFP-MSIMDNVLAGVRAhklvPRKEFRGVAQARLTEVGLwdavkDR--LSDSPFRLSGGQQQLLCLARTLAV 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET 230
Cdd:PRK14271 181 NPEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTV--IIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAET 258


                 ....*
gi 697052228 231 ALFLG 235
Cdd:PRK14271 259 ARYVA 263
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 13-225 3.11e-24

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 103.40  E-value: 3.11e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRR-IGFVPQE--GALF 89
Cdd:PRK10261 336 EVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRdIQFIFQDpyASLD 415

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHLNVADNIAWGL------DGtrHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:PRK10261 416 PRQTVGDSIMEPLrvhgllPG--KAAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSA 493

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 697052228 164 LDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK10261 494 LDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENP 555
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 16-192 4.19e-24

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 97.43  E-value: 4.19e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGFVPqegALFPHLNVA 95
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENILYLGHLP---GLKPELSAL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   96 DNIAWGLDGTRHEKRQRVEALMEMVSLDRqlaTHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRK 174
Cdd:TIGR01189  92 ENLHFWAAIHGGAQRTIEDALAAVGLTGF---EDLPaAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAG 168

                         170
                  ....*....|....*...
gi 697052228  175 ATADLLAEAGVAsILVTH 192
Cdd:TIGR01189 169 LLRAHLARGGIV-LLTTH 185
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 16-204 5.73e-24

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 96.07  E-value: 5.73e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqgrtLFDENSFvpahlrrigFVPQEgalfPHLNva 95
Cdd:cd03223   16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM----PEGEDLL---------FLPQR----PYLP-- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 dniawglDGTrhekrqrvealmemvsLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTG-LRAMtrk 174
Cdd:cd03223   77 -------LGT----------------LREQLIYPWDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEEsEDRL--- 130

                        170       180       190
                 ....*....|....*....|....*....|
gi 697052228 175 atADLLAEAGVASILVTHdQNEALSFATQV 204
Cdd:cd03223  131 --YQLLKELGITVISVGH-RPSLWKFHDRV 157
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 2-230 6.21e-24

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 98.96  E-value: 6.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF-----ETPDTGRIVMQGRTLFDENSFVPAHL 76
Cdd:PRK14258   8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIYERRVNLNRLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPhLNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPH-------EISGGQQQRVALARALA 149
Cdd:PRK14258  88 RQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKHkihksalDLSGGQQQRLCIARALA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 150 QRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRS-----GRFTQVGTPYDVYTR 224
Cdd:PRK14258 167 VKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTKKIFNS 246


                 ....*.
gi 697052228 225 PVDEET 230
Cdd:PRK14258 247 PHDSRT 252
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 16-221 9.66e-24

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 101.66  E-value: 9.66e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL--FDENSFVPahlrRIGFVPQEGALFPHlN 93
Cdd:TIGR01842 333 TLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLkqWDRETFGK----HIGYLPQDVELFPG-T 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   94 VADNIAWGLDGTrhEKRQRVEA-----LMEMVSldrQLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:TIGR01842 408 VAENIARFGENA--DPEKIIEAaklagVHELIL---RLPDGYDTVIgpggatlSGGQRQRIALARALYGDPKLVVLDEPN 482

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  162 SALDTGLRAMTRKATADLLAeAGVASILVTHDQNeALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:TIGR01842 483 SNLDEEGEQALANAIKALKA-RGITVVVITHRPS-LLGCVDKILVLQDGRIARFGERDEV 540
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 2-193 1.13e-23

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 101.67  E-value: 1.13e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQ-VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIG 80
Cdd:TIGR02868 335 LELRDLSAGYPGAPpVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLD--QDEVRRRVS 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   81 FVPQEGALFpHLNVADNIAWGL-DGTRHEkrqrVEALMEMVSLDRQLA------THWPHE----ISGGQQQRVALARALA 149
Cdd:TIGR02868 413 VCAQDAHLF-DTTVRENLRLARpDATDEE----LWAALERVGLADWLRalpdglDTVLGEggarLSGGERQRLALARALL 487

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 697052228  150 QRPSLMLLDEPFSALDtglrAMTRKA-TADLL-AEAGVASILVTHD 193
Cdd:TIGR02868 488 ADAPILLLDEPTEHLD----AETADElLEDLLaALSGRTVVLITHH 529
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 13-225 3.69e-23

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 97.87  E-value: 3.69e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKT----TLLRILAGfetpdTGRIvmQGRTLFDENSFV--PAH----LR--RIG 80
Cdd:PRK09473  28 DVTAVNDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAA-----NGRI--GGSATFNGREILnlPEKelnkLRaeQIS 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQE--GALFPHLNVADNIAWGLdgTRHEKRQRVEALMEMVS-LD-------RQLATHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK09473 101 MIFQDpmTSLNPYMRVGEQLMEVL--MLHKGMSKAEAFEESVRmLDavkmpeaRKRMKMYPHEFSGGMRQRVMIAMALLC 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK09473 179 RPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQP 253
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
9-213 5.08e-23

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 99.32  E-value: 5.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   9 KSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFVPAHLRRIGFVP----Q 84
Cdd:COG1129  260 EGLSVGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPV-RIRSPRDAIRAGIAYVPedrkG 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  85 EGaLFPHLNVADNIA---------WGLDGTRHEkRQRVEALMEMV-----SLDRQLAThwpheISGGQQQRVALARALAQ 150
Cdd:COG1129  339 EG-LVLDLSIRENITlasldrlsrGGLLDRRRE-RALAEEYIKRLriktpSPEQPVGN-----LSGGNQQKVVLAKWLAT 411

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 151 RPSLMLLDEPFSALDTGLRA-----MTRkatadlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFT 213
Cdd:COG1129  412 DPKVLILDEPTRGIDVGAKAeiyrlIRE------LAAEGKAVIVISSELPELLGLSDRILVMREGRIV 473
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
1-192 6.76e-23

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 94.49  E-value: 6.76e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRRIG 80
Cdd:PRK13538   1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQR---DEYHQDLL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLatHWP-HEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK13538  78 YLGHQPGIKTELTALENLRFYQRLHGPGDDEALWEALAQVGLAGFE--DVPvRQLSAGQQRRVALARLWLTRAPLWILDE 155

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 697052228 160 PFSALDTglramtrKATADLL------AEAGVASILVTH 192
Cdd:PRK13538 156 PFTAIDK-------QGVARLEallaqhAEQGGMVILTTH 187
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 12-168 7.34e-23

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 95.03  E-value: 7.34e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfETPDTGRIvmQGRTLFDENSFVPAH-LRRIGFVPQEGALFP 90
Cdd:cd03234   18 KYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISG-RVEGGGTT--SGQILFNGQPRKPDQfQKCVAYVRQDDILLP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 HLNVADNIAWG--LDGTRHeKRQRVEALMEMVSLDRQLA-THWPHE----ISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03234   95 GLTVRETLTYTaiLRLPRK-SSDAIRKKRVEDVLLRDLAlTRIGGNlvkgISGGERRRVSIAVQLLWDPKVLILDEPTSG 173


                 ....*
gi 697052228 164 LDTGL 168
Cdd:cd03234  174 LDSFT 178
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 1-212 7.95e-23

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 98.92  E-value: 7.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFV-PAHLRR- 78
Cdd:PRK10762   4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGK----EVTFNgPKSSQEa 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 -IGFVPQEGALFPHLNVADNIAWGLDGTRH-----EKRQRVEAlmemvslDRQLA----THWPH----EISGGQQQRVAL 144
Cdd:PRK10762  80 gIGIIHQELNLIPQLTIAENIFLGREFVNRfgridWKKMYAEA-------DKLLArlnlRFSSDklvgELSIGEQQMVEI 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 145 ARALAQRPSLMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRF 212
Cdd:PRK10762 153 AKVLSFESKVIIMDEPTDAL-------TDTETESLfrvireLKSQGRGIVYISHRLKEIFEICDDVTVFRDGQF 219
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
16-222 1.03e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 95.92  E-value: 1.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvpaHL----RRIGFVPQ--EGALF 89
Cdd:PRK13633  25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEE-----NLwdirNKAGMVFQnpDNQIV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHLnVADNIAWG---LDGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:PRK13633 100 ATI-VEEDVAFGpenLGIPPEEIRERVDESLKKVGM-YEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDP 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 167 GLRAMTRKATADLLAEAGVASILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13633 178 SGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIF 232
cbiO PRK13646
energy-coupling factor transporter ATPase;
15-222 1.22e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 95.62  E-value: 1.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvPAHLR----RIGFVPQ--EGAL 88
Cdd:PRK13646  21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTK--DKYIRpvrkRIGMVFQfpESQL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FPHlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13646  99 FED-TVEREIIFGpknFKMNLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLD 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 166 TGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13646 178 PQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELF 234
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 1-222 1.35e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 95.68  E-value: 1.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD-VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFVPAHLRR- 78
Cdd:PRK13636   5 ILKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPI-DYSRKGLMKLREs 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQ--EGALFPhLNVADNIAWG---LDGTRHEKRQRVEALMEMVSLD--RQLATHWpheISGGQQQRVALARALAQR 151
Cdd:PRK13636  84 VGMVFQdpDNQLFS-ASVYQDVSFGavnLKLPEDEVRKRVDNALKRTGIEhlKDKPTHC---LSFGQKKRVAIAGVLVME 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 152 PSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVY 222
Cdd:PRK13636 160 PKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF 230
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
4-229 2.05e-22

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 94.85  E-value: 2.05e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvPAHLRRIGFVP 83
Cdd:PRK10575  14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS--KAFARKVAYLP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHLNVADNIAWG-------LDGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLML 156
Cdd:PRK10575  92 QQLPAAEGMTVRELVAIGrypwhgaLGRFGAADREKVEEAISLVGL-KPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 157 LDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEE 229
Cdd:PRK10575 171 LDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQ 243
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 17-218 2.90e-22

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 98.16  E-value: 2.90e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRRIGFVPQEGALFPHLNVAD 96
Cdd:TIGR01257  946 VDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGK---DIETNLDAVRQSLGMCPQHNILFHHLTVAE 1022

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    97 NIAW--GLDGTRHEKRQ-RVEALMEMVSLDRQlATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtglrAMTR 173
Cdd:TIGR01257 1023 HILFyaQLKGRSWEEAQlEMEAMLEDTGLHHK-RNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVD----PYSR 1097

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 697052228   174 KATADLLAE--AGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTP 218
Cdd:TIGR01257 1098 RSIWDLLLKyrSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 15-245 3.25e-22

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 97.47  E-value: 3.25e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKT-TLLRILAGFETPD----TGRIVMQGRTLFDENSFVPAHLR--RIGFVPQEG- 86
Cdd:PRK15134  23 TVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHASEQTLRGVRgnKIAMIFQEPm 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 -ALFPHLNVADNIAWGLdgTRHEKRQRVEALMEMVS-LDR----QLATH---WPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK15134 103 vSLNPLHTLEKQLYEVL--SLHRGMRREAARGEILNcLDRvgirQAAKRltdYPHQLSGGERQRVMIAMALLTRPELLIA 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFL--- 234
Cdd:PRK15134 181 DEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQKLLnse 260

                        250
                 ....*....|...
gi 697052228 235 --GDAVILPAQLA 245
Cdd:PRK15134 261 psGDPVPLPEPAS 273
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 2-239 5.71e-22

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 96.41  E-value: 5.71e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFET--PDTGRIVMQ----------GRTLFD-- 67
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIIYHvalcekcgyvERPSKVge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   68 -----ENSFVPAHL--------------RRIGFVPQEG-ALFPHLNVADNIAWGLDGTRHEKR---QRVEALMEMVSLDR 124
Cdd:TIGR03269  81 pcpvcGGTLEPEEVdfwnlsdklrrrirKRIAIMLQRTfALYGDDTVLDNVLEALEEIGYEGKeavGRAVDLIEMVQLSH 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  125 QLaTHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQV 204
Cdd:TIGR03269 161 RI-THIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKA 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 697052228  205 AVMRSGRFTQVGTPYDVYTR------PVDEETALFLGDAVI 239
Cdd:TIGR03269 240 IWLENGEIKEEGTPDEVVAVfmegvsEVEKECEVEVGEPII 280
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 13-216 7.69e-22

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 92.21  E-value: 7.69e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR--TLFDENSfvpahlrriGFVPQegalfp 90
Cdd:cd03220   34 EFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRvsSLLGLGG---------GFNPE------ 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  91 hLNVADNI-----AWGLDGTrhEKRQRVEALMEMVSL----DRQLATHwpheiSGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03220   99 -LTGRENIylngrLLGLSRK--EIDEKIDEIIEFSELgdfiDLPVKTY-----SSGMKARLAFAIATALEPDILLIDEVL 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 162 SALDTGLRamtRKATADL--LAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03220  171 AVGDAAFQ---EKCQRRLreLLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 16-192 8.43e-22

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 91.40  E-value: 8.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGFVPqegALFPHLNVA 95
Cdd:cd03231   15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAP---GIKTTLSVL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWGLDgtRHEKRQRVEALMEMvslDRQLATHWP-HEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRK 174
Cdd:cd03231   92 ENLRFWHA--DHSDEQVEEALARV---GLNGFEDRPvAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAE 166

                        170
                 ....*....|....*...
gi 697052228 175 ATADLLAEAGVAsILVTH 192
Cdd:cd03231  167 AMAGHCARGGMV-VLTTH 183
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 8-225 1.08e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 93.76  E-value: 1.08e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   8 SKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL---FDENSFVPAHL-------- 76
Cdd:PRK13631  33 EKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIgdkKNNHELITNPYskkiknfk 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 ---RRIGFVPQ--EGALFPHlNVADNIAWG---LDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARAL 148
Cdd:PRK13631 113 elrRRVSMVFQfpEYQLFKD-TIEKDIMFGpvaLGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGIL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 149 AQRPSLMLLDEPFSALD-TGLRAMTrkataDLLAEA---GVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:PRK13631 192 AIQPEILIFDEPTAGLDpKGEHEMM-----QLILDAkanNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTD 266


                 .
gi 697052228 225 P 225
Cdd:PRK13631 267 Q 267
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-211 3.37e-21

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 90.71  E-value: 3.37e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvpAHLRR-- 78
Cdd:PRK11614   5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQT---AKIMRea 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEGALFPHLNVADNIAW-GLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK11614  82 VAIVPEGRRVFSRMTVEENLAMgGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 697052228 158 DEPFSALdTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK11614 162 DEPSLGL-APIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGH 214
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 14-213 3.67e-21

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 93.94  E-value: 3.67e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRR--IGFVPQE---GAL 88
Cdd:COG3845  271 VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLS---PRERRRlgVAYIPEDrlgRGL 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FPHLNVADNIAwgLDGTRHEK------------RQRVEALME-----MVSLD---RQLathwpheiSGGQQQRVALARAL 148
Cdd:COG3845  348 VPDMSVAENLI--LGRYRRPPfsrggfldrkaiRAFAEELIEefdvrTPGPDtpaRSL--------SGGNQQKVILAREL 417

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 149 AQRPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFT 213
Cdd:COG3845  418 SRDPKLLIAAQPTRGLDVGAIEFIHQRLLE-LRDAGAAVLLISEDLDEILALSDRIAVMYEGRIV 481
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 15-193 5.38e-21

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 93.85  E-value: 5.38e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdensfVPAHLRRIGFVPQEGALFPHLNV 94
Cdd:TIGR03719  19 EILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEA-------------RPQPGIKVGYLPQEPQLDPTKTV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGLDGTRH-----------------------EKRQRVEALMEMV---SLDRQL-----ATHWP------HEISGG 137
Cdd:TIGR03719  86 RENVEEGVAEIKDaldrfneisakyaepdadfdklaAEQAELQEIIDAAdawDLDSQLeiamdALRCPpwdadvTKLSGG 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  138 QQQRVALARALAQRPSLMLLDEPFSALDTglramtrKATADL---LAEAGVASILVTHD 193
Cdd:TIGR03719 166 ERRRVALCRLLLSKPDMLLLDEPTNHLDA-------ESVAWLerhLQEYPGTVVAVTHD 217
nickel_nikD TIGR02770
nickel import ATP-binding protein NikD; This family represents the NikD subunit of a ...
 18-235 7.26e-21

nickel import ATP-binding protein NikD; This family represents the NikD subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. NikD and NikE are homologous. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131817 [Multi-domain]  Cd Length: 230  Bit Score: 89.74  E-value: 7.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   18 DSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmQGRTLFDENSFVPAHLR--RIGFVPQE--GALFPHLN 93
Cdd:TIGR02770   3 QDLNLSLKRGEVLALVGESGSGKSLTCLAILGLLPPGLTQT--SGEILLDGRPLLPLSIRgrHIATIMQNprTAFNPLFT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   94 VADNIAWGLdgTRHEK-----RQRVEALMEMVSLD--RQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:TIGR02770  81 MGNHAIETL--RSLGKlskqaRALILEALEAVGLPdpEEVLKKYPFQLSGGMLQRVMIALALLLEPPFLIADEPTTDLDV 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  167 GLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALFLG 235
Cdd:TIGR02770 159 VNQARVLKLLRELRQLFGTGILLITHDLGVVARIADEVAVMDDGRIVERGTVKEIFYNPKHETTRKLLS 227
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 16-217 8.03e-21

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 93.65  E-value: 8.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensFVPAHLRR-IGFVPQEGALFPHlNV 94
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKD---IDRHTLRQfINYLPQEPYIFSG-SI 564

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGL-DGTRHEKRQRVEALMEM--------VSLDRQLATHwPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:TIGR01193 565 LENLLLGAkENVSQDEIWAACEIAEIkddienmpLGYQTELSEE-GSSISGGQKQRIALARALLTDSKVLILDESTSNLD 643

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 697052228  166 TGLRamtRKATADLLAEAGVASILVTHdqneALSFATQ---VAVMRSGRFTQVGT 217
Cdd:TIGR01193 644 TITE---KKIVNNLLNLQDKTIIFVAH----RLSVAKQsdkIIVLDHGKIIEQGS 691
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2-212 1.78e-20

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 91.90  E-value: 1.78e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL-FdeNSFVPAHLRRIG 80
Cdd:PRK11288   5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMrF--ASTTAALAAGVA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTRH----------EKRQRVEALMEMVSLDRQLAthwphEISGGQQQRVALARALAQ 150
Cdd:PRK11288  83 IIYQELHLVPEMTVAENLYLGQLPHKGgivnrrllnyEAREQLEHLGVDIDPDTPLK-----YLSIGQRQMVEIAKALAR 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 697052228 151 RPSLMLLDEPFSALDTglRAMTR--KATADLLAEaGVASILVTHDQNEALSFATQVAVMRSGRF 212
Cdd:PRK11288 158 NARVIAFDEPTSSLSA--REIEQlfRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRY 218
cbiO PRK13644
energy-coupling factor transporter ATPase;
1-244 2.02e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 89.28  E-value: 2.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSD-VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDEnSFVPAHLRRI 79
Cdd:PRK13644   1 MIRLENVSYSYPDgTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDF-SKLQGIRKLV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVPQEGAL-FPHLNVADNIAWGLDG---TRHEKRQRVEALMEMVSLDRqLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK13644  80 GIVFQNPETqFVGRTVEEDLAFGPENlclPPIEIRKRVDRALAEIGLEK-YRHRSPKTLSGGQGQCVALAGILTMEPECL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 156 LLDEPFSALD--TGLRAMTRkatADLLAEAGVASILVTHDQNEaLSFATQVAVMRSGRFTQVGTPYDVYTRPVDEETALF 233
Cdd:PRK13644 159 IFDEVTSMLDpdSGIAVLER---IKKLHEKGKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVSLQTLGLT 234

                        250
                 ....*....|.
gi 697052228 234 LGDAVILPAQL 244
Cdd:PRK13644 235 PPSLIELAENL 245
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 2-193 2.94e-20

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 91.54  E-value: 2.94e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqGRTLfdensfvpahlrRIGF 81
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV------------KLAY 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   82 VPQE-GALFPHLNVADNIAWGLDGTRHEKRqrvealmEMVS-----------LDRQLAThwpHEISGGQQQRVALARALA 149
Cdd:TIGR03719 390 VDQSrDALDPNKTVWEEISGGLDIIKLGKR-------EIPSrayvgrfnfkgSDQQKKV---GQLSGGERNRVHLAKTLK 459

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 697052228  150 QRPSLMLLDEPFSALDT-GLRAMTRKatadLLAEAGVAsILVTHD 193
Cdd:TIGR03719 460 SGGNVLLLDEPTNDLDVeTLRALEEA----LLNFAGCA-VVISHD 499
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
1-224 3.29e-20

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 88.91  E-value: 3.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIG 80
Cdd:PRK13638   1 MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQ--EGALFpHLNVADNIAWGLDG---TRHEKRQRVEALMEMVslDRQLATHWPHE-ISGGQQQRVALARALAQRPSL 154
Cdd:PRK13638  81 TVFQdpEQQIF-YTDIDSDIAFSLRNlgvPEAEITRRVDEALTLV--DAQHFRHQPIQcLSHGQKKRVAIAGALVLQARY 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 155 MLLDEPFSALDTGLRAMTrKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:PRK13638 158 LLLDEPTAGLDPAGRTQM-IAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFAC 226
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 2-216 4.59e-20

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 86.21  E-value: 4.59e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSF--SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdENSFVPAHLRR- 78
Cdd:cd03247    1 LSINNVSFSYpeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGV----PVSDLEKALSSl 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFVPQEgalfPHLnvadniawgLDGTrhekrqrveaLMEmvSLDRQLathwpheiSGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03247   77 ISVLNQR----PYL---------FDTT----------LRN--NLGRRF--------SGGERQRLALARILLQDAPIVLLD 123

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 159 EPFSALDtglrAMTRKATADLLAEA--GVASILVTHdQNEALSFATQVAVMRSGRFTQVG 216
Cdd:cd03247  124 EPTVGLD----PITERQLLSLIFEVlkDKTLIWITH-HLTGIEHMDKILFLENGKIIMQG 178
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 2-231 5.30e-20

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 87.92  E-value: 5.30e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLR-------ILAGFETpdTGRIVMQGRTLFDENSFVPA 74
Cdd:PRK14243  11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRV--EGKVTFHGKNLYAPDVDPVE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  75 HLRRIGFVPQEGALFPHlNVADNIAWG--LDGTRHEKRQRVE-ALMEMVSLD------RQLAThwphEISGGQQQRVALA 145
Cdd:PRK14243  89 VRRRIGMVFQKPNPFPK-SIYDNIAYGarINGYKGDMDELVErSLRQAALWDevkdklKQSGL----SLSGGQQQRLCIA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 146 RALAQRPSLMLLDEPFSALDtglrAMTRKATADLLAEAG--VASILVTHDQNEALSFATQVAVM---------RSGRFTQ 214
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALD----PISTLRIEELMHELKeqYTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVE 239

                        250
                 ....*....|....*..
gi 697052228 215 VGTPYDVYTRPVDEETA 231
Cdd:PRK14243 240 FDRTEKIFNSPQQQATR 256
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
1-217 2.29e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 88.69  E-value: 2.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlFDENSFVPAHLRRIG 80
Cdd:PRK09700   5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNIN-YNKLDHKLAAQLGIG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTR----------HEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQ 150
Cdd:PRK09700  84 IIYQELSVIDELTVLENLYIGRHLTKkvcgvniidwREMRVRAAMMLLRVGLKVDLDEK-VANLSISHKQMLEIAKTLML 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 151 RPSLMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGrfTQVGT 217
Cdd:PRK09700 163 DAKVIIMDEPTSSL-------TNKEVDYLflimnqLRKEGTAIVYISHKLAEIRRICDRYTVMKDG--SSVCS 226
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 1-225 2.43e-19

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 85.81  E-value: 2.43e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAHL-RRI 79
Cdd:PRK11300   5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHI----EGLPGHQiARM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  80 GFVP--QEGALF------------PHLNVADNIAWGLDGTRHEKRQRVEAL------MEMVSLdRQLATHWPHEISGGQQ 139
Cdd:PRK11300  81 GVVRtfQHVRLFremtvienllvaQHQQLKTGLFSGLLKTPAFRRAESEALdraatwLERVGL-LEHANRQAGNLAYGQQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 140 QRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:PRK11300 160 RRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPE 239


                 ....*.
gi 697052228 220 DVYTRP 225
Cdd:PRK11300 240 EIRNNP 245
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 16-195 4.35e-19

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 84.62  E-value: 4.35e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDTGRIVMqgrtlfDENSFvpahlrrigfvPQEGALFPHLN 93
Cdd:COG2401   45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDV------PDNQF-----------GREASLIDAIG 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  94 VADNIAwgldgtrhekrQRVEALmEMVSL-DRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMT 172
Cdd:COG2401  108 RKGDFK-----------DAVELL-NAVGLsDAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRV 175

                        170       180
                 ....*....|....*....|...
gi 697052228 173 RKATADLLAEAGVASILVTHDQN 195
Cdd:COG2401  176 ARNLQKLARRAGITLVVATHHYD 198
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 15-165 5.91e-19

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 87.48  E-value: 5.91e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIV-MQGRTlfdensfvpahlrrIGFVPQEGALFPHLN 93
Cdd:PRK11819  21 QILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARpAPGIK--------------VGYLPQEPQLDPEKT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  94 VADNIAWGLDGTRhEKRQRVEALMEMVS---------------------------LDRQL-----ATHWPH------EIS 135
Cdd:PRK11819  87 VRENVEEGVAEVK-AALDRFNEIYAAYAepdadfdalaaeqgelqeiidaadawdLDSQLeiamdALRCPPwdakvtKLS 165

                        170       180       190
                 ....*....|....*....|....*....|
gi 697052228 136 GGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK11819 166 GGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 26-219 6.51e-19

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 87.80  E-value: 6.51e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   26 PGSRTAIVGPSGSGKTTLLRILAGFETPDT---GRIVMQGRTLfdENSFvpahLRRI-GFVPQEGALFPHLNVADNIAW- 100
Cdd:TIGR00955  50 PGELLAVMGSSGAGKTTLMNALAFRSPKGVkgsGSVLLNGMPI--DAKE----MRAIsAYVQQDDLFIPTLTVREHLMFq 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  101 -----GLDGTRHEKRQRVEALMEMVSLD--RQLATHWPHE---ISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRA 170
Cdd:TIGR00955 124 ahlrmPRRVTKKEKRERVDEVLQALGLRkcANTRIGVPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAY 203

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 697052228  171 MTRKATADlLAEAGVASILVTHD-QNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:TIGR00955 204 SVVQVLKG-LAQKGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPD 252
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 2-217 2.03e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 86.03  E-value: 2.03e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQ--VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTL--FDEnsfvpAHLR 77
Cdd:PRK11160 339 LTLNNVSFTYPDQPqpVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIadYSE-----AALR 413

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 R-IGFVPQEGALFPHlNVADNIAWGLDGTRHEKR----QRV--EALMEMVS-LD-------RQLathwpheiSGGQQQRV 142
Cdd:PRK11160 414 QaISVVSQRVHLFSA-TLRDNLLLAAPNASDEALievlQQVglEKLLEDDKgLNawlgeggRQL--------SGGEQRRL 484

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 143 ALARALAQRPSLMLLDEPFSALDtglrAMTRKATADLLAE--AGVASILVTHDQNeALSFATQVAVMRSGRFTQVGT 217
Cdd:PRK11160 485 GIARALLHDAPLLLLDEPTEGLD----AETERQILELLAEhaQNKTVLMITHRLT-GLEQFDRICVMDNGQIIEQGT 556
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 2-218 2.59e-18

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 82.81  E-value: 2.59e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDTGRIVMQGRTLFDEnsfvPAHLR-R 78
Cdd:COG0396    1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILEL----SPDERaR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IG-FV----PQEgalFPHLNVAD------NIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHE-ISGGQQQRVALAR 146
Cdd:COG0396   77 AGiFLafqyPVE---IPGVSVSNflrtalNARRGEELSAREFLKLLKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQ 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 147 ALAQRPSLMLLDEPFSALDT-GLRAMTRKATAdlLAEAGVASILVTHdQNEALSF--ATQVAVMRSGRFTQVGTP 218
Cdd:COG0396  154 MLLLEPKLAILDETDSGLDIdALRIVAEGVNK--LRSPDRGILIITH-YQRILDYikPDFVHVLVDGRIVKSGGK 225
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 2-211 4.92e-18

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 81.03  E-value: 4.92e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDTGRIVMQGRTLFDensfVPAHLRR- 78
Cdd:cd03217    1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITD----LPPEERAr 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 --IGFVPQEGALFPHLNVAD---NIAWGLdgtrhekrqrvealmemvsldrqlathwpheiSGGQQQRVALARALAQRPS 153
Cdd:cd03217   77 lgIFLAFQYPPEIPGVKNADflrYVNEGF--------------------------------SGGEKKRNEILQLLLLEPD 124

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 154 LMLLDEPFSALD-TGLRAMTRkaTADLLAEAGVASILVTHdQNEALSF--ATQVAVMRSGR 211
Cdd:cd03217  125 LAILDEPDSGLDiDALRLVAE--VINKLREEGKSVLIITH-YQRLLDYikPDRVHVLYDGR 182
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 11-193 5.78e-18

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 83.21  E-value: 5.78e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRRIGFV-PQEGALF 89
Cdd:COG4586   32 YREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVPFKRR---KEFARRIGVVfGQRSQLW 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHLNVADNIA-----WGLDGTRHekRQRVEALMEMVSLD-------RQLathwpheiSGGQQQRVALARALAQRPSLMLL 157
Cdd:COG4586  109 WDLPAIDSFRllkaiYRIPDAEY--KKRLDELVELLDLGelldtpvRQL--------SLGQRMRCELAAALLHRPKILFL 178

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 697052228 158 DEPfsaldT-GLRAMTRKATADLL----AEAGVASILVTHD 193
Cdd:COG4586  179 DEP-----TiGLDVVSKEAIREFLkeynRERGTTILLTSHD 214
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-193 5.82e-18

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 82.08  E-value: 5.82e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfvpahlrRIG 80
Cdd:PRK09544   4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKL-------------RIG 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNvadniawgLDGTRHEK-RQRVEALMEMVSLDRQLATH---WP-HEISGGQQQRVALARALAQRPSLM 155
Cdd:PRK09544  71 YVPQKLYLDTTLP--------LTVNRFLRlRPGTKKEDILPALKRVQAGHlidAPmQKLSGGETQRVLLARALLNRPQLL 142

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 697052228 156 LLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHD 193
Cdd:PRK09544 143 VLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHD 180
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 4-230 1.23e-17

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 83.63  E-value: 1.23e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFVPAHLRRIGFVP 83
Cdd:PRK10982   1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEI-DFKSSKEALENGISMVH 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHLNVADNIAWGLDGTR-----HEKRQR-VEALMEMVSLD----RQLAThwpheISGGQQQRVALARALAQRPS 153
Cdd:PRK10982  80 QELNLVLQRSVMDNMWLGRYPTKgmfvdQDKMYRdTKAIFDELDIDidprAKVAT-----LSVSQMQMIEIAKAFSYNAK 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 154 LMLLDEPFSALdtglramTRKATADL------LAEAGVASILVTHDQNEALSFATQVAVMRSGRFtqvgtpydVYTRPVD 227
Cdd:PRK10982 155 IVIMDEPTSSL-------TEKEVNHLftiirkLKERGCGIVYISHKMEEIFQLCDEITILRDGQW--------IATQPLA 219


                 ...
gi 697052228 228 EET 230
Cdd:PRK10982 220 GLT 222
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 14-225 1.72e-17

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 83.37  E-value: 1.72e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKT----TLLRIL--AGFETpDTGRIVMQGRT--LFDENSFVPAHLRR-----IG 80
Cdd:PRK10261  29 IAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLeqAGGLV-QCDKMLLRRRSrqVIELSEQSAAQMRHvrgadMA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQE--GALFPHLNVADNIAWGLdgTRHEKRQRVEALME---MVSLDR-----QLATHWPHEISGGQQQRVALARALAQ 150
Cdd:PRK10261 108 MIFQEpmTSLNPVFTVGEQIAESI--RLHQGASREEAMVEakrMLDQVRipeaqTILSRYPHQLSGGMRQRVMIAMALSC 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 151 RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK10261 186 RPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAP 260
PLN03211 PLN03211
ABC transporter G-25; Provisional
 8-166 1.77e-17

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 83.39  E-value: 1.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   8 SKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--TGRIVMQGRTLFDENsfvpahLRRIGFVPQE 85
Cdd:PLN03211  75 TRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPTKQI------LKRTGFVTQD 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 GALFPHLNVADNIAW------GLDGTRHEKRQRVEALMEMVSLDR----QLATHWPHEISGGQQQRVALARALAQRPSLM 155
Cdd:PLN03211 149 DILYPHLTVRETLVFcsllrlPKSLTKQEKILVAESVISELGLTKcentIIGNSFIRGISGGERKRVSIAHEMLINPSLL 228

                        170
                 ....*....|.
gi 697052228 156 LLDEPFSALDT 166
Cdd:PLN03211 229 ILDEPTSGLDA 239
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
15-165 3.63e-17

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 82.32  E-value: 3.63e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRR-IGFVPQEGALFpHLN 93
Cdd:PRK13657 349 QGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDG---TDIRTVTRASLRRnIAVVFQDAGLF-NRS 424

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  94 VADNIAWGL-DGTRHEKR---QRVEALMEMVSLDRQLATHWPH---EISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK13657 425 IEDNIRVGRpDATDEEMRaaaERAQAHDFIERKPDGYDTVVGErgrQLSGGERQRLAIARALLKDPPILILDEATSALD 503
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
13-166 4.12e-17

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 82.37  E-value: 4.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDensFVPAHLRR-IGFVPQEGALFpH 91
Cdd:PRK11176 355 EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRD---YTLASLRNqVALVSQNVHLF-N 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LNVADNIAWGLDG--TRH--EKRQRVEALMEMVS-LDRQLATHWPHE---ISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:PRK11176 431 DTIANNIAYARTEqySREqiEEAARMAYAMDFINkMDNGLDTVIGENgvlLSGGQRQRIAIARALLRDSPILILDEATSA 510


                 ...
gi 697052228 164 LDT 166
Cdd:PRK11176 511 LDT 513
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-225 6.12e-17

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 80.17  E-value: 6.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQV----LDSLNLSVAPGSRTAIVGPSGSGKT-TLLRILAGFETPdtGRiVMQGRTLFDENSF--VP 73
Cdd:PRK11022   3 LLNVDKLSVHFGDESApfraVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYP--GR-VMAEKLEFNGQDLqrIS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  74 AHLRR--IG------FVPQEGALFPHLNVADNIAWGLD----GTRHEKRQRVEALMEMVSLD--RQLATHWPHEISGGQQ 139
Cdd:PRK11022  80 EKERRnlVGaevamiFQDPMTSLNPCYTVGFQIMEAIKvhqgGNKKTRRQRAIDLLNQVGIPdpASRLDVYPHQLSGGMS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 140 QRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPY 219
Cdd:PRK11022 160 QRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAH 239


                 ....*.
gi 697052228 220 DVYTRP 225
Cdd:PRK11022 240 DIFRAP 245
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 16-218 1.19e-16

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 77.53  E-value: 1.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAH-LR-RIGFVPQEGALFPHlN 93
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDI----SKIGLHdLRsRISIIPQDPVLFSG-T 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  94 VADNiawgLD-GTRHEKRQRVEALmEMVSLDR---QLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:cd03244   94 IRSN----LDpFGEYSDEELWQAL-ERVGLKEfveSLPGGLDTVVeeggenlSVGQRQLLCLARALLRKSKILVLDEATA 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 163 ALDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSFAtQVAVMRSGRFTQVGTP 218
Cdd:cd03244  169 SVDPETDALIQKTIREAFKDCTV--LTIAHRLDTIIDSD-RILVLDKGRVVEFDSP 221
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 12-226 1.20e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 78.05  E-value: 1.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQV---LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRIVMQGRTLFDENSFVPAHlRRIGFVPQEGAL 88
Cdd:PRK03695   4 NDVAVstrLGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELAR-HRAYLSQQQTPP 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FP---------HLNVADNIAwgldgtrhEKRQRVEALMEMVSLDRQLATHwPHEISGGQQQRVALARALAQ-RPS----- 153
Cdd:PRK03695  82 FAmpvfqyltlHQPDKTRTE--------AVASALNEVAEALGLDDKLGRS-VNQLSGGEWQRVRLAAVVLQvWPDinpag 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 154 -LMLLDEPFSALDtglraMTRKATADLL----AEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPV 226
Cdd:PRK03695 153 qLLLLDEPMNSLD-----VAQQAALDRLlselCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPEN 225
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 15-165 1.30e-16

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 76.90  E-value: 1.30e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--TGRIVMQGRTLfdensfVPAHLRRIGFVPQEGALFPHL 92
Cdd:cd03232   21 QLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGviTGEILINGRPL------DKNFQRSTGYVEQQDVHSPNL 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228  93 NVadniawgldgtrhekrqrVEALMEMVSLdrqlathwpHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03232   95 TV------------------REALRFSALL---------RGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLD 140
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 2-193 1.33e-16

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 80.55  E-value: 1.33e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqGRTLfdensfvpahlrRIGF 81
Cdd:PRK11819 325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV------------KLAY 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQE-GALFPHLNVADNIAWGLDGTRHEKRqrvealmEMVSL-----------DRQLAThwpHEISGGQQQRVALARALA 149
Cdd:PRK11819 392 VDQSrDALDPNKTVWEEISGGLDIIKVGNR-------EIPSRayvgrfnfkggDQQKKV---GVLSGGERNRLHLAKTLK 461

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 697052228 150 QRPSLMLLDEPFSALDT-GLRAMtRKAtadLLAEAGVAsILVTHD 193
Cdd:PRK11819 462 QGGNVLLLDEPTNDLDVeTLRAL-EEA---LLEFPGCA-VVISHD 501
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 1-217 5.12e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 79.29  E-value: 5.12e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228     1 MLELTAISKSFSDVQ--VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVpaHlRR 78
Cdd:TIGR01257 1937 ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDV--H-QN 2013

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    79 IGFVPQEGALFPHLNVADNIAW--GLDGTRHEKRQRV-----EALMEMVSLDRQLATHwpheiSGGQQQRVALARALAQR 151
Cdd:TIGR01257 2014 MGYCPQFDAIDDLLTGREHLYLyaRLRGVPAEEIEKVanwsiQSLGLSLYADRLAGTY-----SGGNKRKLSTAIALIGC 2088

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228   152 PSLMLLDEPFSALDTGLRAMTRKATADLLAEaGVASILVTHDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:TIGR01257 2089 PPLVLLDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGT 2153
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
1-203 7.22e-16

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 75.27  E-value: 7.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvpaHLRRIG 80
Cdd:PRK13543  11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-----RSRFMA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAW--GLDGtRHEKRQRVEALMeMVSLDRQLAThWPHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK13543  86 YLGHLPGLKADLSTLENLHFlcGLHG-RRAKQMPGSALA-IVGLAGYEDT-LVRQLSAGQKKRLALARLWLSPAPLWLLD 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 697052228 159 EPFSALD-TGLRAMTRKATADLlaEAGVASILVTHDQNEALSFATQ 203
Cdd:PRK13543 163 EPYANLDlEGITLVNRMISAHL--RGGGAALVTTHGAYAAPPVRTR 206
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 14-193 7.28e-16

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 75.91  E-value: 7.28e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRT-----AIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdensfvPAHLRRIGFVPQE-GA 87
Cdd:cd03237    7 KKTLGEFTLEVEGGSISeseviGILGPNGIGKTTFIKMLAGVLKPDEGDI--------------EIELDTVSYKPQYiKA 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  88 LFPhLNVADNIAWGLDGTRHEKRQRVEAL--MEMVSL-DRQLAthwphEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:cd03237   73 DYE-GTVRDLLSSITKDFYTHPYFKTEIAkpLQIEQIlDREVP-----ELSGGELQRVAIAACLSKDADIYLLDEPSAYL 146

                        170       180
                 ....*....|....*....|....*....
gi 697052228 165 DTGLRAMTRKATADLLAEAGVASILVTHD 193
Cdd:cd03237  147 DVEQRLMASKVIRRFAENNEKTAFVVEHD 175
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
1-193 7.42e-16

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 78.31  E-value: 7.42e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSfsdvqvLDSLNLSVAPGS-RT----AIVGPSGSGKTTLLRILAGFETPDTGRIVmqgRTLfdensfvpah 75
Cdd:PRK13409 340 LVEYPDLTKK------LGDFSLEVEGGEiYEgeviGIVGPNGIGKTTFAKLLAGVLKPDEGEVD---PEL---------- 400

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  76 lrRIGFVPQEGALFPHLNVAD---NIAWGLDGT--RHE--KRQRVEALMemvslDRQLAthwphEISGGQQQRVALARAL 148
Cdd:PRK13409 401 --KISYKPQYIKPDYDGTVEDllrSITDDLGSSyyKSEiiKPLQLERLL-----DKNVK-----DLSGGELQRVAIAACL 468

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 697052228 149 AQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHD 193
Cdd:PRK13409 469 SRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHD 513
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
7-223 1.04e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 77.90  E-value: 1.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQvldSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFVPAHLRRIGFVPQ-- 84
Cdd:PRK09700 272 TSRDRKKVR---DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDI-SPRSPLDAVKKGMAYITEsr 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  85 -EGALFPHLNVADNIA-------------WGLDGTRHEKR----QRVEALMEMVSLDRQLAthwphEISGGQQQRVALAR 146
Cdd:PRK09700 348 rDNGFFPNFSIAQNMAisrslkdggykgaMGLFHEVDEQRtaenQRELLALKCHSVNQNIT-----ELSGGNQQKVLISK 422

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 147 ALAQRPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYT 223
Cdd:PRK09700 423 WLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQ-LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMS 498
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 15-218 1.28e-15

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 74.37  E-value: 1.28e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  15 QVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdenSFVPAH-LRR-IGFVPQEGALFphl 92
Cdd:cd03369   22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDI----STIPLEdLRSsLTIIPQDPTLF--- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  93 nvADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLathwpheiSGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMT 172
Cdd:cd03369   95 --SGTIRSNLDPFDEYSDEEIYGALRVSEGGLNL--------SQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALI 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 697052228 173 RKATADLLAEAGVASIlvTHDQNEALSFAtQVAVMRSGRFTQVGTP 218
Cdd:cd03369  165 QKTIREEFTNSTILTI--AHRLRTIIDYD-KILVMDAGEVKEYDHP 207
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 2-224 1.56e-15

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 77.24  E-value: 1.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVmqgrtlFDENSfvpahlrRIGF 81
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVK------WSENA-------NIGY 386

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQE-GALFPH-LNVADNIA-WGLDGtrhEKRQRVEALmemvsLDRQL-----ATHWPHEISGGQQQRVALARALAQRPS 153
Cdd:PRK15064 387 YAQDhAYDFENdLTLFDWMSqWRQEG---DDEQAVRGT-----LGRLLfsqddIKKSVKVLSGGEKGRMLFGKLMMQKPN 458

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 154 LMLLDEPFSALDT----GLRAMTRKATADLlaeagvasILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:PRK15064 459 VLVMDEPTNHMDMesieSLNMALEKYEGTL--------IFVSHDREFVSSLATRIIEITPDGVVDFSGTYEEYLR 525
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 12-246 1.71e-15

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 75.12  E-value: 1.71e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTtlLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLR--RIGFVPQ--EGA 87
Cdd:PRK10418  14 AAQPLVHGVSLTLQRGRVLALVGGSGSGKS--LTCAAALGILPAGVRQTAGRVLLDGKPVAPCALRgrKIATIMQnpRSA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  88 LFPHLNVADN-IAWGLDGTRHEKRQRVEALMEMVSLD--RQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:PRK10418  92 FNPLHTMHTHaRETCLALGKPADDATLTAALEAVGLEnaARVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 165 DTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEET-ALFLGDAVILPAQ 243
Cdd:PRK10418 172 DVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTrSLVSAHLALYGME 251


                 ...
gi 697052228 244 LAA 246
Cdd:PRK10418 252 LAS 254
PLN03130 PLN03130
ABC transporter C family member; Provisional
 17-165 1.80e-15

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 77.86  E-value: 1.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfETPDT--GRIVMQGRtlfdensfvpahlrrIGFVPQEGALFpHLNV 94
Cdd:PLN03130  633 LSNINLDVPVGSLVAIVGSTGEGKTSLISAMLG-ELPPRsdASVVIRGT---------------VAYVPQVSWIF-NATV 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGL--DGTRHEKRQRVEALMEMVSLdrqLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PLN03130  696 RDNILFGSpfDPERYERAIDVTALQHDLDL---LPGGDLTEIgergvniSGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 10-165 2.03e-15

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 77.30  E-value: 2.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR----------------TLFDensFVP 73
Cdd:PRK11147  12 SFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDlivarlqqdpprnvegTVYD---FVA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  74 A------------H--LRRIGFVPQEGAL---------FPHLNvadniAWGLDgtrhekrQRVEALMEMVSL--DRQLAt 128
Cdd:PRK11147  89 EgieeqaeylkryHdiSHLVETDPSEKNLnelaklqeqLDHHN-----LWQLE-------NRINEVLAQLGLdpDAALS- 155

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 697052228 129 hwphEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PRK11147 156 ----SLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD 188
hmuV PRK13547
heme ABC transporter ATP-binding protein;
16-223 2.99e-15

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 74.86  E-value: 2.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--------TGRIVMQGRTLFDENSFVPAHLRRIgfVPQEG- 86
Cdd:PRK13547  16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPRLARLRAV--LPQAAq 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  87 -------------ALFPHLNVAdniawglDGTRHEKRQ---RVEALMEMVSLDRQLAThwphEISGGQQQRVALARALAQ 150
Cdd:PRK13547  94 pafafsareivllGRYPHARRA-------GALTHRDGEiawQALALAGATALVGRDVT----TLSGGELARVQFARVLAQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 151 ---------RPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDV 221
Cdd:PRK13547 163 lwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADV 242


                 ..
gi 697052228 222 YT 223
Cdd:PRK13547 243 LT 244
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 2-193 3.33e-15

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 76.36  E-value: 3.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFsdvqvlDSLNLSVAPGS-----RTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdenSFVPAHL 76
Cdd:COG1245  342 VEYPDLTKSY------GGFSLEVEGGEiregeVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKI-----SYKPQYI 410

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 RRIGFVPQEGALFPHLNVAdniawgLDGT--RHE--KRQRVEALMemvslDRQLAthwphEISGGQQQRVALARALAQRP 152
Cdd:COG1245  411 SPDYDGTVEEFLRSANTDD------FGSSyyKTEiiKPLGLEKLL-----DKNVK-----DLSGGELQRVAIAACLSRDA 474

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHD 193
Cdd:COG1245  475 DLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHD 515
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 12-210 3.79e-15

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 73.52  E-value: 3.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRiVMQGRTLFDENSFVPAHLRR---IGFVPQEGAL 88
Cdd:cd03290   12 SGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGK-VHWSNKNESEPSFEATRSRNrysVAYAAQKPWL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 FpHLNVADNIAWGldgtRHEKRQRVEALMEMVSL--DRQLATHWPH--------EISGGQQQRVALARALAQRPSLMLLD 158
Cdd:cd03290   91 L-NATVEENITFG----SPFNKQRYKAVTDACSLqpDIDLLPFGDQteigergiNLSGGQRQRICVARALYQNTNIVFLD 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 159 EPFSALDTGLR-AMTRKATADLLAEAGVASILVTHdQNEALSFATQVAVMRSG 210
Cdd:cd03290  166 DPFSALDIHLSdHLMQEGILKFLQDDKRTLVLVTH-KLQYLPHADWIIAMKDG 217
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 12-219 3.94e-15

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 76.52  E-value: 3.94e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfdensfvpahlrrIGFVPQEgALFPH 91
Cdd:TIGR00957  649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS---------------VAYVPQQ-AWIQN 712

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    92 LNVADNIAWGLDGTRHEKRQRVEAL-----MEMV-SLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:TIGR00957  713 DSLRENILFGKALNEKYYQQVLEACallpdLEILpSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228   166 TGL-RAMTRKATADLLAEAGVASILVTHdqneALSFATQV---AVMRSGRFTQVGtPY 219
Cdd:TIGR00957  793 AHVgKHIFEHVIGPEGVLKNKTRILVTH----GISYLPQVdviIVMSGGKISEMG-SY 845
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
17-200 7.61e-15

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 73.38  E-value: 7.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfVPAHLRR--IGFVPQEGAL---FPH 91
Cdd:PRK15056  23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQP-------TRQALQKnlVAYVPQSEEVdwsFPV 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 LnVADNIAWGLDG-------TRHEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:PRK15056  96 L-VEDVVMMGRYGhmgwlrrAKKRDRQIVTAALARVDMvefrHRQIG-----ELSGGQKKRVFLARAIAQQGQVILLDEP 169

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 697052228 161 FSALDTGLRAMTRKATADLLAEaGVASILVTHDQNEALSF 200
Cdd:PRK15056 170 FTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEF 208
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-165 2.92e-14

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 74.18  E-value: 2.92e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdensfvpAHLRRIGFVPQEGALFPHlNVA 95
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI---------------KHSGRISFSPQTSWIMPG-TIK 504

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228    96 DNIAWGLDGTRHEKRQRVEA--LMEMVSL----DRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:TIGR01271  505 DNIIFGLSYDEYRYTSVIKAcqLEEDIALfpekDKTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 17-211 5.29e-14

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 72.55  E-value: 5.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG-FETPDTGRIVMQGRTLFDEN---------SFVPAHLRRIGFVPQEG 86
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVFINGKPVDIRNpaqairagiAMVPEDRKRHGIVPILG 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   87 alfphlnVADNIAWG-LDgtRHEKRQRVEALMEMVSLDR-----QLATHWPH----EISGGQQQRVALARALAQRPSLML 156
Cdd:TIGR02633 356 -------VGKNITLSvLK--SFCFKMRIDAAAELQIIGSaiqrlKVKTASPFlpigRLSGGNQQKAVLAKMLLTNPRVLI 426

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 697052228  157 LDEPFSALDTGLRAMTRKATaDLLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:TIGR02633 427 LDEPTRGVDVGAKYEIYKLI-NQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGK 480
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 16-217 7.27e-14

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 71.04  E-value: 7.27e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdensfvpAHLRRIGFVPQEGALFPHlNVA 95
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI---------------KHSGRISFSSQFSWIMPG-TIK 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  96 DNIAWGLDGTRHEKRQRVEA------LMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGL- 168
Cdd:cd03291  116 ENIIFGVSYDEYRYKSVVKAcqleedITKFPEKDNTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTe 195

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 697052228 169 RAMTRKATADLLAEAgvASILVThDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:cd03291  196 KEIFESCVCKLMANK--TRILVT-SKMEHLKKADKILILHEGSSYFYGT 241
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 10-197 9.57e-14

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 71.97  E-value: 9.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfETPDT--------GRIVMQGRTLFDENsfvpahlRRIGF 81
Cdd:PRK10938 269 SYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQGysndltlfGRRRGSGETIWDIK-------KHIGY 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VpqEGALfpHL------NVADNIAWGL-------DGTRHEKRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARAL 148
Cdd:PRK10938 341 V--SSSL--HLdyrvstSVRNVILSGFfdsigiyQAVSDRQQKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRAL 416

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 697052228 149 AQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEA 197
Cdd:PRK10938 417 VKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDA 465
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-160 1.29e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 71.69  E-value: 1.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfetpdtGRIVMQGR-TLFDENSFVPAHLR---- 77
Cdd:NF033858   3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAG------ARKIQQGRvEVLGGDMADARHRRavcp 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  78 RIGFVPQ--EGALFPHLNVADNIA-----WGLDgtRHEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALAR 146
Cdd:NF033858  77 RIAYMPQglGKNLYPTLSVFENLDffgrlFGQD--AAERRRRIDELLRATGLapfaDRPAG-----KLSGGMKQKLGLCC 149

                        170
                 ....*....|....
gi 697052228 147 ALAQRPSLMLLDEP 160
Cdd:NF033858 150 ALIHDPDLLILDEP 163
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
14-225 1.59e-13

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 70.32  E-value: 1.59e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRI-----VMQGRTLFDensfVPAHLRR------IGFV 82
Cdd:COG4170   20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGI-TKDNWHVtadrfRWNGIDLLK----LSPRERRkiigreIAMI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  83 PQE--GALFPHLNVADNI-----AWGLDGT----RHEKRQRVEALMEMVSL--DRQLATHWPHEISGGQQQRVALARALA 149
Cdd:COG4170   95 FQEpsSCLDPSAKIGDQLieaipSWTFKGKwwqrFKWRKKRAIELLHRVGIkdHKDIMNSYPHELTEGECQKVMIAMAIA 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228 150 QRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:COG4170  175 NQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
10-192 2.26e-13

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 70.90  E-value: 2.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFS---DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRR-IGFVPQE 85
Cdd:PRK10790 347 SFAyrdDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPL---SSLSHSVLRQgVAMVQQD 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 GALFPHlNVADNIAWGldgtRHEKRQRVEALMEMVSLdRQLATHWPHEI-----------SGGQQQRVALARALAQRPSL 154
Cdd:PRK10790 424 PVVLAD-TFLANVTLG----RDISEEQVWQALETVQL-AELARSLPDGLytplgeqgnnlSVGQKQLLALARVLVQTPQI 497

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 155 MLLDEPFSALDTG--------LRAMTRKATADLLA-------EAGvaSILVTH 192
Cdd:PRK10790 498 LILDEATANIDSGteqaiqqaLAAVREHTTLVVIAhrlstivEAD--TILVLH 548
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 10-214 2.51e-13

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 71.21  E-value: 2.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   10 SFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGF--------------ETPDTGRIVMQ-------------- 61
Cdd:PTZ00265 1177 SRPNVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFydlkndhhivfkneHTNDMTNEQDYqgdeeqnvgmknvn 1256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   62 --------------------GRTLFDENSFVPAHLRRI----GFVPQEGALFpHLNVADNIAWGLDGTRHEKRQRV---E 114
Cdd:PTZ00265 1257 efsltkeggsgedstvfknsGKILLDGVDICDYNLKDLrnlfSIVSQEPMLF-NMSIYENIKFGKEDATREDVKRAckfA 1335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  115 ALMEMV-SLDRQLATH---WPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILV 190
Cdd:PTZ00265 1336 AIDEFIeSLPNKYDTNvgpYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITI 1415

                         250       260
                  ....*....|....*....|....*...
gi 697052228  191 THdQNEALSFATQVAVM----RSGRFTQ 214
Cdd:PTZ00265 1416 AH-RIASIKRSDKIVVFnnpdRTGSFVQ 1442
PLN03232 PLN03232
ABC transporter C family member; Provisional
 17-165 3.08e-13

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 70.78  E-value: 3.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   17 LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETP-DTGRIVMQGRtlfdensfvpahlrrIGFVPQEGALFpHLNVA 95
Cdd:PLN03232  633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHaETSSVVIRGS---------------VAYVPQVSWIF-NATVR 696

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 697052228   96 DNIAWGLD--GTRHEKRQRVEALMEMVSL----DRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:PLN03232  697 ENILFGSDfeSERYWRAIDVTALQHDLDLlpgrDLTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALD 772
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 1-272 5.11e-13

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 69.66  E-value: 5.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdENSFvpAHLRRIG 80
Cdd:PRK10938   3 SLQISQGTFRLSDTKTLQLPSLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGER---------QSQF--SHITRLS 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 F------VPQEgalFPHLNvADNIAWGLDGT----------RHEKRQRVEALMEMVSLDRQLATHWPHeISGGQQQRVAL 144
Cdd:PRK10938  72 FeqlqklVSDE---WQRNN-TDMLSPGEDDTgrttaeiiqdEVKDPARCEQLAQQFGITALLDRRFKY-LSTGETRKTLL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 145 ARALAQRPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVytr 224
Cdd:PRK10938 147 CQALMSEPDLLILDEPFDGLDVASRQQLAELLAS-LHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEI--- 222

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 697052228 225 pvdeetalfLGDAVIlpAQLA-----AGYAVCALGEVPTDNAQATGQGRVMMR 272
Cdd:PRK10938 223 ---------LQQALV--AQLAhseqlEGVQLPEPDEPSARHALPANEPRIVLN 264
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 1-165 1.03e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 66.13  E-value: 1.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSfvpAHLRRIG 80
Cdd:PRK13540   1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLC---TYQKQLC 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 FVPQEGALFPHLNVADNIAWGLDGTrhEKRQRVEALMEMVSLDRQLatHWP-HEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:PRK13540  78 FVGHRSGINPYLTLRENCLYDIHFS--PGAVGITELCRLFSLEHLI--DYPcGLLSSGQKRQVALLRLWMSKAKLWLLDE 153


                 ....*.
gi 697052228 160 PFSALD 165
Cdd:PRK13540 154 PLVALD 159
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 23-193 1.10e-12

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 67.01  E-value: 1.10e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  23 SVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRivMQGRTLFDE--NSFVPAHLR-----------RIGFVPQEGALF 89
Cdd:cd03236   22 VPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--FDDPPDWDEilDEFRGSELQnyftkllegdvKVIVKPQYVDLI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  90 PHL---NVADNIawgldgTRHEKRQRVEALMEMVSLDRQLATHWPHeISGGQQQRVALARALAQRPSLMLLDEPFSALDT 166
Cdd:cd03236  100 PKAvkgKVGELL------KKKDERGKLDELVDQLELRHVLDRNIDQ-LSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172

                        170       180
                 ....*....|....*....|....*..
gi 697052228 167 GLRaMTRKATADLLAEAGVASILVTHD 193
Cdd:cd03236  173 KQR-LNAARLIRELAEDDNYVLVVEHD 198
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 7-211 1.53e-12

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 65.75  E-value: 1.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   7 ISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGfETPDTGRIvmQGRTLFDENSFVPAHL---RRIGFVP 83
Cdd:cd03233   13 TGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN-RTEGNVSV--EGDIHYNGIPYKEFAEkypGEIIYVS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  84 QEGALFPHLNVADNIAWGLDGTRHekrqrvealmEMVSldrqlathwphEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:cd03233   90 EEDVHFPTLTVRETLDFALRCKGN----------EFVR-----------GISGGERKRVSIAEALVSRASVLCWDNSTRG 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 697052228 164 LD--TGLR-AMTRKATADLLAEAGVASILVTHDqnEALSFATQVAVMRSGR 211
Cdd:cd03233  149 LDssTALEiLKCIRTMADVLKTTTFVSLYQASD--EIYDLFDKVLVLYEGR 197
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 1-194 1.82e-12

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 68.27  E-value: 1.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVM----------QGRTLF---D 67
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLakgiklgyfaQHQLEFlraD 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  68 ENSFvpAHLRRIGFVPQEGALFPHLNvadniAWGLDGTRhekrqrvealmemvsldrqlATHWPHEISGGQQQRVALARA 147
Cdd:PRK10636 392 ESPL--QHLARLAPQELEQKLRDYLG-----GFGFQGDK--------------------VTEETRRFSGGEKARLVLALI 444

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 697052228 148 LAQRPSLMLLDEPFSALDTGLramtRKATADLLAEAGVASILVTHDQ 194
Cdd:PRK10636 445 VWQRPNLLLLDEPTNHLDLDM----RQALTEALIDFEGALVVVSHDR 487
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 26-202 2.05e-12

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 63.93  E-value: 2.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    26 PGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqgrtlfdensfvpahlrrigfvpqegalfphlnvadniawgLDGT 105
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIY-----------------------------------------IDGE 39

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   106 RHEKRQRVEALMEMVsldrqlaTHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRK-----ATADLL 180
Cdd:smart00382  40 DILEEVLDQLLLIIV-------GGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelrLLLLLK 112

                          170       180
                   ....*....|....*....|..
gi 697052228   181 AEAGVASILVTHDQNEALSFAT 202
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGPALL 134
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 20-214 3.49e-12

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 67.00  E-value: 3.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  20 LNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRRIGFV--P---QEGALFphlnV 94
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEI---NALSTAQRLARGLVylPedrQSSGLY----L 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAWGLDGTRHE------KRQRVEALMEmvSLDRQLATHWPHE------ISGGQQQRVALARALAQRPSLMLLDEPFS 162
Cdd:PRK15439 355 DAPLAWNVCALTHNrrgfwiKPARENAVLE--RYRRALNIKFNHAeqaartLSGGNQQKVLIAKCLEASPQLLIVDEPTR 432

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 697052228 163 ALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQ 214
Cdd:PRK15439 433 GVDVSARNDIYQLIRS-IAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISG 483
PTZ00243 PTZ00243
ABC transporter; Provisional
 16-211 5.91e-12

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 67.11  E-value: 5.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG-FEtpdtgriVMQGRTLFDensfvpahlRRIGFVPQEgALFPHLNV 94
Cdd:PTZ00243  675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSqFE-------ISEGRVWAE---------RSIAYVPQQ-AWIMNATV 737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWgLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSALD-- 165
Cdd:PTZ00243  738 RGNILF-FDEEDAARLADAVRVSQLEADLAQLGGGLETEIgekgvnlSGGQKARVSLARAVYANRDVYLLDDPLSALDah 816

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 697052228  166 TGLRAMTRkatADLLAEAGVASILVTHdQNEALSFATQVAVMRSGR 211
Cdd:PTZ00243  817 VGERVVEE---CFLGALAGKTRVLATH-QVHVVPRADYVVALGDGR 858
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 26-193 6.06e-12

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 66.35  E-value: 6.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  26 PGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVM-----------QGRTLFDensfvpaHLRRIgfvpQEGALfphlNV 94
Cdd:COG1245   98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEepswdevlkrfRGTELQD-------YFKKL----ANGEI----KV 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 A------DNIAWGLDGT------RHEKRQRVEALMEMVSL----DRQLAthwphEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:COG1245  163 AhkpqyvDLIPKVFKGTvrelleKVDERGKLDELAEKLGLenilDRDIS-----ELSGGELQRVAIAAALLRDADFYFFD 237

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 159 EPFSALDTGLRAMTRKATADlLAEAGVASILVTHD 193
Cdd:COG1245  238 EPSSYLDIYQRLNVARLIRE-LAEEGKYVLVVEHD 271
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 1-217 1.25e-11

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 63.89  E-value: 1.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFetPD----TGRIVMQGRTLFDENSFVPAHL 76
Cdd:CHL00131   7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGH--PAykilEGDILFKGESILDLEPEERAHL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  77 R-RIGF-VPQEgalFPHLNVAD--NIAWgldGTRHEKRQRVEA-----------LMEMVSLDRQLATHWPHE-ISGGQQQ 140
Cdd:CHL00131  85 GiFLAFqYPIE---IPGVSNADflRLAY---NSKRKFQGLPELdplefleiineKLKLVGMDPSFLSRNVNEgFSGGEKK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 141 RVALARALAQRPSLMLLDEPFSALDT-GLRAMTRkaTADLLAEAGVASILVTHDQNeALSFATQ--VAVMRSGRFTQVGT 217
Cdd:CHL00131 159 RNEILQMALLDSELAILDETDSGLDIdALKIIAE--GINKLMTSENSIILITHYQR-LLDYIKPdyVHVMQNGKIIKTGD 235
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
12-217 1.40e-11

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 65.50  E-value: 1.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  12 SDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQEGALFPH 91
Cdd:PRK10789 326 TDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQ--LDSWRSRLAVVSQTPFLFSD 403

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 lNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHEI-------SGGQQQRVALARALAQRPSLMLLDEPFSAL 164
Cdd:PRK10789 404 -TVANNIALGRPDATQQEIEHVARLASVHDDILRLPQGYDTEVgergvmlSGGQKQRISIARALLLNAEILILDDALSAV 482

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 165 D--------TGLRAMTRKATadllaeagvasILVTHDQNEALSFATQVAVMRSGRFTQVGT 217
Cdd:PRK10789 483 DgrtehqilHNLRQWGEGRT-----------VIISAHRLSALTEASEILVMQHGHIAQRGN 532
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
2-224 1.87e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 64.37  E-value: 1.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLlRILAGFETPDTGRIVMQGRTLFDENSfvpAHLRRIGF 81
Cdd:NF000106  14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RG-ALPAHV*GPDAGRRPWRF*TWCANRR---ALRRTIG* 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 -VPQEGALFPHLNVADN---IAWGLDGTRHEKRQRVEALMEMVSLDrQLATHWPHEISGGQQQRVALARALAQRPSLMLL 157
Cdd:NF000106  90 hRPVR*GRRESFSGRENlymIGR*LDLSRKDARARADELLERFSLT-EAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYL 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 158 DEPfsalDTGLRAMTRKATAD---LLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTR 224
Cdd:NF000106 169 DEP----TTGLDPRTRNEVWDevrSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 4-211 1.96e-11

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 64.95  E-value: 1.96e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   4 LTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAG-FETPDTGRIVMQGRTLFDENS---------FVP 73
Cdd:PRK13549 265 LTAWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGaYPGRWEGEIFIDGKPVKIRNPqqaiaqgiaMVP 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  74 AHLRRIGFVPQegalfphLNVADNIAWG-LDgtRHEKRQRVEALMEMVSLDRQLA-----THWPH----EISGGQQQRVA 143
Cdd:PRK13549 345 EDRKRDGIVPV-------MGVGKNITLAaLD--RFTGGSRIDDAAELKTILESIQrlkvkTASPElaiaRLSGGNQQKAV 415

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 144 LARALAQRPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK13549 416 LAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQ-LVQQGVAIIVISSELPEVLGLSDRVLVMHEGK 482
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
21-211 2.67e-11

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 64.55  E-value: 2.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  21 NLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSfvPAHLRRIGFV------PQEGaLFPHLNV 94
Cdd:PRK11288 273 SFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPI-DIRS--PRDAIRAGIMlcpedrKAEG-IIPVHSV 348

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  95 ADNIAwgLDGTRHEKRQR--VEALMEMVSLDRQLA-----THWPHE----ISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:PRK11288 349 ADNIN--ISARRHHLRAGclINNRWEAENADRFIRslnikTPSREQlimnLSGGNQQKAILGRWLSEDMKVILLDEPTRG 426

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 697052228 164 LDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK11288 427 IDVGAKHEIYNVIYE-LAAQGVAVLFVSSDLPEVLGVADRIVVMREGR 473
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 13-201 4.79e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 63.97  E-value: 4.79e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETpdTGRI-----VMQGRTLfdENSFVpahlRRIGFVPQEGA 87
Cdd:TIGR00956  775 KRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVT--TGVItggdrLVNGRPL--DSSFQ----RSIGYVQQQDL 846

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    88 LFPHLNVADNIAWGL------DGTRHEKRQRVEALMEMVSLdRQLATHWPHEISGG----QQQRVALARALAQRPSLML- 156
Cdd:TIGR00956  847 HLPTSTVRESLRFSAylrqpkSVSKSEKMEYVEEVIKLLEM-ESYADAVVGVPGEGlnveQRKRLTIGVELVAKPKLLLf 925

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 697052228   157 LDEPFSALDtglrAMTRKATADL---LAEAGVAsILVTHDQNEALSFA 201
Cdd:TIGR00956  926 LDEPTSGLD----SQTAWSICKLmrkLADHGQA-ILCTIHQPSAILFE 968
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 13-192 5.50e-11

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 63.89  E-value: 5.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   13 DVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQgrtlfDENSFVPAHLR----RIGFVPQEGAL 88
Cdd:PTZ00265  397 DVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN-----DSHNLKDINLKwwrsKIGVVSQDPLL 471

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   89 FPHlNVADNIAWGL---------------DG--------TRHEKRQRVEALM-------------------------EMV 120
Cdd:PTZ00265  472 FSN-SIKNNIKYSLyslkdlealsnyyneDGndsqenknKRNSCRAKCAGDLndmsnttdsneliemrknyqtikdsEVV 550

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  121 SLDRQLATH-----WP-----------HEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAG 184
Cdd:PTZ00265  551 DVSKKVLIHdfvsaLPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNEN 630


                  ....*...
gi 697052228  185 VASILVTH 192
Cdd:PTZ00265  631 RITIIIAH 638
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 16-192 1.32e-10

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 62.46  E-value: 1.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPdtgriVMQGRTLFDENSfvpahlrRIGFVPQEgalfPHLNVA 95
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGEL-WP-----VYGGRLTKPAKG-------KLFYVPQR----PYMTLG 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   96 ---DNIAWGlDGTRHEKR-----QRVEALMEMVSLDRQL--------ATHWPHEISGGQQQRVALARALAQRPSLMLLDE 159
Cdd:TIGR00954 530 tlrDQIIYP-DSSEDMKRrglsdKDLEQILDNVQLTHILereggwsaVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDE 608

                         170       180       190
                  ....*....|....*....|....*....|....
gi 697052228  160 PFSALDTGLR-AMTRkatadLLAEAGVASILVTH 192
Cdd:TIGR00954 609 CTSAVSVDVEgYMYR-----LCREFGITLFSVSH 637
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
14-225 1.33e-10

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 61.74  E-value: 1.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRIVMQgRTLFDENSFV---PAHLRR-----IGFVPQE 85
Cdd:PRK15093  20 VKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGV-TKDNWRVTAD-RMRFDDIDLLrlsPRERRKlvghnVSMIFQE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 --GALFPHLNVADNI-----AWGLDGT-----RHEKRQRVEALMEMVSLDRQLATH-WPHEISGGQQQRVALARALAQRP 152
Cdd:PRK15093  98 pqSCLDPSERVGRQLmqnipGWTYKGRwwqrfGWRKRRAIELLHRVGIKDHKDAMRsFPYELTEGECQKVMIAIALANQP 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 153 SLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASILVTHDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRP 225
Cdd:PRK15093 178 RLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTP 250
PLN03073 PLN03073
ABC transporter F family; Provisional
 10-213 2.02e-10

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 61.80  E-value: 2.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQ--------VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIvmqgrtlfdensFVPAHLRRigf 81
Cdd:PLN03073 510 SFSDASfgypggplLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTV------------FRSAKVRM--- 574

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 vpqegALFPHLNVAdniawGLDGTRHE-----------KRQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQ 150
Cdd:PLN03073 575 -----AVFSQHHVD-----GLDLSSNPllymmrcfpgvPEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFK 644

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 697052228 151 RPSLMLLDEPFSALDtgLRAMTRKATADLLAEAGVasILVTHDQNEALSFATQVAVMRSGRFT 213
Cdd:PLN03073 645 KPHILLLDEPSNHLD--LDAVEALIQGLVLFQGGV--LMVSHDEHLISGSVDELWVVSEGKVT 703
PLN03232 PLN03232
ABC transporter C family member; Provisional
 16-233 3.54e-10

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 61.53  E-value: 3.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRRI-GFVPQEGALFphlnv 94
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDD---CDVAKFGLTDLRRVlSIIPQSPVLF----- 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGLDG-TRHEKRQRVEAL-----MEMVS-----LDRQLaTHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:PLN03232 1323 SGTVRFNIDPfSEHNDADLWEALerahiKDVIDrnpfgLDAEV-SEGGENFSVGQRQLLSLARALLRRSKILVLDEATAS 1401

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  164 LDTGLRAMTRKATADLLAEAGVasILVTHDQNEALSfATQVAVMRSGRFTQVGTPYDVYTRpvdEETALF 233
Cdd:PLN03232 1402 VDVRTDSLIQRTIREEFKSCTM--LVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSR---DTSAFF 1465
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 3-193 4.68e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 60.73  E-value: 4.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   3 ELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMqGRTL----FDEnsfvpahlrr 78
Cdd:PRK11147 321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-GTKLevayFDQ---------- 389

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 igfvpQEGALFPHLNVADNIAWG-----LDG-TRH-----------EKRQR--VEALmemvsldrqlathwpheiSGGQQ 139
Cdd:PRK11147 390 -----HRAELDPEKTVMDNLAEGkqevmVNGrPRHvlgylqdflfhPKRAMtpVKAL------------------SGGER 446

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 140 QRVALARaLAQRPS-LMLLDEPFSALDTglramtrkATADLLAEAgVAS-----ILVTHD 193
Cdd:PRK11147 447 NRLLLAR-LFLKPSnLLILDEPTNDLDV--------ETLELLEEL-LDSyqgtvLLVSHD 496
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 20-159 6.19e-10

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 60.20  E-value: 6.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  20 LNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfVPAHLRRIGFVPQEGALFPHLnvadnia 99
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADN--REAYRQLFSAVFSDFHLFDRL------- 421

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228 100 WGLDGTrhEKRQRVEALMEMVSLDRQLA--------ThwphEISGGQQQRVALARALA-QRPsLMLLDE 159
Cdd:COG4615  422 LGLDGE--ADPARARELLERLELDHKVSvedgrfstT----DLSQGQRKRLALLVALLeDRP-ILVFDE 483
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 10-165 6.38e-10

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 57.72  E-value: 6.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  10 SFSDVQV--LDSLNLSVAPGSRTAIVGPSGSGKTTLLriLAGFETPDTGRIVmQGRTLFDENSFVpahlrrigFVPQEGA 87
Cdd:cd03238    2 TVSGANVhnLQNLDVSIPLNVLVVVTGVSGSGKSTLV--NEGLYASGKARLI-SFLPKFSRNKLI--------FIDQLQF 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  88 LfphlnvadnIAWGLdgtrhekrqrvealmEMVSLDRQLAThwpheISGGQQQRVALARALAQRP--SLMLLDEPFSALD 165
Cdd:cd03238   71 L---------IDVGL---------------GYLTLGQKLST-----LSGGELQRVKLASELFSEPpgTLFILDEPSTGLH 121
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 16-218 6.67e-10

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 58.77  E-value: 6.67e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLlrILAGFETPDT--GRIVMQGRTLfdenSFVPAH-LR-RIGFVPQEGALFph 91
Cdd:cd03288   36 VLKHVKAYIKPGQKVGICGRTGSGKSSL--SLAFFRMVDIfdGKIVIDGIDI----SKLPLHtLRsRLSIILQDPILF-- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  92 lnvADNIAWGLDGTRHEKRQRVEALMEMVSLDRQ----------LATHWPHEISGGQQQRVALARALAQRPSLMLLDEPF 161
Cdd:cd03288  108 ---SGSIRFNLDPECKCTDDRLWEALEIAQLKNMvkslpggldaVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEAT 184

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 162 SALDTGLRAMTRKATADLLAEAGVASIlvTHDQNEALSfATQVAVMRSGRFTQVGTP 218
Cdd:cd03288  185 ASIDMATENILQKVVMTAFADRTVVTI--AHRVSTILD-ADLVLVLSRGILVECDTP 238
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 32-211 2.02e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 58.48  E-value: 2.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  32 IVGPSG---SGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvpahlrrigfvPQEG---------------ALFPHLN 93
Cdd:PRK10762 280 ILGVSGlmgAGRTELMKVLYGALPRTSGYVTLDGHEVVTRS-------------PQDGlangivyisedrkrdGLVLGMS 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  94 VADNI----------AWGldGTRH-EKRQRVEALMEMV-----SLDRQLAthwphEISGGQQQRVALARALAQRPSLMLL 157
Cdd:PRK10762 347 VKENMsltalryfsrAGG--SLKHaDEQQAVSDFIRLFniktpSMEQAIG-----LLSGGNQQKVAIARGLMTRPKVLIL 419

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228 158 DEPFSALDTGlramTRKATADLL---AEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK10762 420 DEPTRGVDVG----AKKEIYQLInqfKAEGLSIILVSSEMPEVLGMSDRILVMHEGR 472
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 1-215 3.67e-09

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 56.72  E-value: 3.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFE--TPDTGRIVMQGRTLFD--------ENS 70
Cdd:PRK09580   1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLElspedragEGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  71 FVP-AHLRRIGFVPQEGALFPHLNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHWPHE-ISGGQQQRVALARAL 148
Cdd:PRK09580  81 FMAfQYPVEIPGVSNQFFLQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLKMPEDLLTRSVNVgFSGGEKKRNDILQMA 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 697052228 149 AQRPSLMLLDEPFSALDT-GLRAMTRKATAdlLAEAGVASILVTHDQN-------EALSFATQVAVMRSGRFTQV 215
Cdd:PRK09580 161 VLEPELCILDESDSGLDIdALKIVADGVNS--LRDGKRSFIIVTHYQRildyikpDYVHVLYQGRIVKSGDFTLV 233
PLN03130 PLN03130
ABC transporter C family member; Provisional
 16-174 4.79e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 57.83  E-value: 4.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGrtlFDENSFVPAHLRRI-GFVPQEGALFphlnv 94
Cdd:PLN03130 1254 VLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDG---CDISKFGLMDLRKVlGIIPQAPVLF----- 1325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   95 ADNIAWGLDG-TRHEKRQRVEALMEM----------VSLDRQLAtHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:PLN03130 1326 SGTVRFNLDPfNEHNDADLWESLERAhlkdvirrnsLGLDAEVS-EAGENFSVGQRQLLSLARALLRRSKILVLDEATAA 1404

                         170
                  ....*....|.
gi 697052228  164 LDTGLRAMTRK 174
Cdd:PLN03130 1405 VDVRTDALIQK 1415
PLN03140 PLN03140
ABC transporter G family member; Provisional
 14-165 5.06e-09

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 57.93  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPD--TGRIVMQGRTLFDENsfvpahLRRI-GFVPQEGALFP 90
Cdd:PLN03140  893 LQLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGyiEGDIRISGFPKKQET------FARIsGYCEQNDIHSP 966

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   91 HLNVADNIAWGL------DGTRHEKRQRVEALMEMVSLD--RQLATHWP--HEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:PLN03140  967 QVTVRESLIYSAflrlpkEVSKEEKMMFVDEVMELVELDnlKDAIVGLPgvTGLSTEQRKRLTIAVELVANPSIIFMDEP 1046


                  ....*
gi 697052228  161 FSALD 165
Cdd:PLN03140 1047 TSGLD 1051
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
26-193 6.21e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.13  E-value: 6.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  26 PGSRTAIVGPSGSGKTTLLRILAGFETPDTGRI--------VMQ---GRTLFD------ENSFVPAHlrrigfVPQEgal 88
Cdd:PRK13409  98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGDYeeepswdeVLKrfrGTELQNyfkklyNGEIKVVH------KPQY--- 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  89 fphlnvADNIAWGLDGT------RHEKRQRVEALMEMVSL----DRQLathwpHEISGGQQQRVALARALAQRPSLMLLD 158
Cdd:PRK13409 169 ------VDLIPKVFKGKvrellkKVDERGKLDEVVERLGLenilDRDI-----SELSGGELQRVAIAAALLRDADFYFFD 237

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 159 EPFSALDTGLRAMTRKATADLLAEAGVasILVTHD 193
Cdd:PRK13409 238 EPTSYLDIRQRLNVARLIRELAEGKYV--LVVEHD 270
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 6-193 6.35e-09

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 54.89  E-value: 6.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   6 AISKSFSDVQVLDSLNlSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTlfdensfvpahlrrIGFVPQE 85
Cdd:cd03222    5 DCVKRYGVFFLLVELG-VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGIT--------------PVYKPQY 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  86 galfphlnvadniawgldgtrhekrqrvealmemVSLdrqlathwpheiSGGQQQRVALARALAQRPSLMLLDEPFSALD 165
Cdd:cd03222   70 ----------------------------------IDL------------SGGELQRVAIAAALLRNATFYLFDEPSAYLD 103

                        170       180
                 ....*....|....*....|....*...
gi 697052228 166 TGLRAMTRKATADLLAEAGVASILVTHD 193
Cdd:cd03222  104 IEQRLNAARAIRRLSEEGKKTALVVEHD 131
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 16-221 1.08e-08

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 56.88  E-value: 1.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    16 VLDSLNLSVAPGSRTAIVGPSGSGKTT----LLRILAGFEtpdtGRIVMQGRTLFDensfVPAH-LR-RIGFVPQEGALF 89
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSltlgLFRINESAE----GEIIIDGLNIAK----IGLHdLRfKITIIPQDPVLF 1372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    90 ---------PHLNVADNIAWGLDGTRHEKrQRVEALMEmvSLDRQLAtHWPHEISGGQQQRVALARALAQRPSLMLLDEP 160
Cdd:TIGR00957 1373 sgslrmnldPFSQYSDEEVWWALELAHLK-TFVSALPD--KLDHECA-EGGENLSVGQRQLVCLARALLRKTKILVLDEA 1448

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228   161 FSALDTGLRAMTRKATADLLAEAGVASIlvTHDQNEALSFaTQVAVMRSGRFTQVGTPYDV 221
Cdd:TIGR00957 1449 TAAVDLETDNLIQSTIRTQFEDCTVLTI--AHRLNTIMDY-TRVIVLDKGEVAEFGAPSNL 1506
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 14-234 1.04e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 53.57  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    14 VQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILA----GFETPDTGRIVMQGRTLFDENSFVPAHLRRIGfvpQEGALF 89
Cdd:TIGR00956   74 FDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIKKHYRGDVVYNA---ETDVHF 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    90 PHLNVADNIAW----------GLDGTRHEKRQRVEAL-MEMVSLDRQLATHWPHE----ISGGQQQRVALARALAQRPSL 154
Cdd:TIGR00956  151 PHLTVGETLDFaarcktpqnrPDGVSREEYAKHIADVyMATYGLSHTRNTKVGNDfvrgVSGGERKRVSIAEASLGGAKI 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   155 MLLDEPFSALD--TGL---RAMtrKATADLLAeagvASILVTHDQ--NEALSFATQVAVMRSGrftqvgtpYDVYTRPVD 227
Cdd:TIGR00956  231 QCWDNATRGLDsaTALefiRAL--KTSANILD----TTPLVAIYQcsQDAYELFDKVIVLYEG--------YQIYFGPAD 296


                   ....*..
gi 697052228   228 EETALFL 234
Cdd:TIGR00956  297 KAKQYFE 303
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 1-195 1.06e-07

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 51.41  E-value: 1.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   1 MLELTAISKSFSDVQVLDsLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfdeNSFVPAHLRRIG 80
Cdd:PRK13541   1 MLSLHQLQFNIEQKNLFD-LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNI---NNIAKPYCTYIG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  81 fvpQEGALFPHLNVADNIA-WGldgtrhEKRQRVEALMEMVS-------LDRQLAThwpheISGGQQQRVALARALAQRP 152
Cdd:PRK13541  77 ---HNLGLKLEMTVFENLKfWS------EIYNSAETLYAAIHyfklhdlLDEKCYS-----LSSGMQKIVAIARLIACQS 142

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 697052228 153 SLMLLDEpfsaLDTGLRAMTRKATADLL---AEAGVASILVTHDQN 195
Cdd:PRK13541 143 DLWLLDE----VETNLSKENRDLLNNLIvmkANSGGIVLLSSHLES 184
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-192 1.25e-07

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 53.38  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDtGRIVMQGRTLfdeNSFVPAHLRR-IGFVPQEGALF----- 89
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSW---NSVTLQTWRKaFGVIPQKVFIFsgtfr 1309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228    90 ----PHLNVADNIAWgldgtRHEKRQRVEALMEMV--SLDRQLATHwPHEISGGQQQRVALARALAQRPSLMLLDEPFSA 163
Cdd:TIGR01271 1310 knldPYEQWSDEEIW-----KVAEEVGLKSVIEQFpdKLDFVLVDG-GYVLSNGHKQLMCLARSILSKAKILLLDEPSAH 1383

                          170       180
                   ....*....|....*....|....*....
gi 697052228   164 LDTGLRAMTRKATADLLAEAGVasILVTH 192
Cdd:TIGR01271 1384 LDPVTLQIIRKTLKQSFSNCTV--ILSEH 1410
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 30-195 1.31e-07

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 51.45  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  30 TAIVGPSGSGKTTLLR-ILAGF--ETPDTGRIVMQGRTLFDENSfvpahlrRIGFVpqegalfpHLNVadniaWGLDGTR 106
Cdd:cd03240   25 TLIVGQNGAGKTTIIEaLKYALtgELPPNSKGGAHDPKLIREGE-------VRAQV--------KLAF-----ENANGKK 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 107 HEKRQRVEALMEMVSLdRQLATHWPHEI-----SGGQQQ------RVALARALAQRPSLMLLDEPFSALDTGLRamtRKA 175
Cdd:cd03240   85 YTITRSLAILENVIFC-HQGESNWPLLDmrgrcSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENI---EES 160

                        170       180
                 ....*....|....*....|....
gi 697052228 176 TADLLAEAGVAS----ILVTHDQN 195
Cdd:cd03240  161 LAEIIEERKSQKnfqlIVITHDEE 184
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 20-214 4.04e-07

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 51.51  E-value: 4.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  20 LNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENsfvPAHLRR-IGFVPQEGALFPHLnvadni 98
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQ---PEDYRKlFSAVFTDFHLFDQL------ 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  99 aWGLDGTRHEKrQRVEALMEMVSLDRQLaTHWPHEI-----SGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTR 173
Cdd:PRK10522 413 -LGPEGKPANP-ALVEKWLERLKMAHKL-ELEDGRIsnlklSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREFY 489

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 697052228 174 KATADLLAEAGVASILVTHDqNEALSFATQVAVMRSGRFTQ 214
Cdd:PRK10522 490 QVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQLSE 529
PTZ00243 PTZ00243
ABC transporter; Provisional
 11-168 2.08e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 49.78  E-value: 2.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   11 FSDVQ---------VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRtlfDENSFVPAHLRR-IG 80
Cdd:PTZ00243 1311 FEGVQmryreglplVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGR---EIGAYGLRELRRqFS 1387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   81 FVPQEGALFPHlNVADNIAWGLDGTRHEkrqrVEALMEMVSLDRQLAThwphEISG--------------GQQQRVALAR 146
Cdd:PTZ00243 1388 MIPQDPVLFDG-TVRQNVDPFLEASSAE----VWAALELVGLRERVAS----ESEGidsrvleggsnysvGQRQLMCMAR 1458

                         170       180
                  ....*....|....*....|...
gi 697052228  147 ALAQRPS-LMLLDEPFSALDTGL 168
Cdd:PTZ00243 1459 ALLKKGSgFILMDEATANIDPAL 1481
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 25-166 2.96e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 46.58  E-value: 2.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  25 APGSRTAIVGPSGSGKTTLLR---ILAGFETPDTGRivmqgRTLFDENSFVPA-HLRRIGFVPQegalfphlnvadniaw 100
Cdd:cd03227   19 GEGSLTIITGPNGSGKSTILDaigLALGGAQSATRR-----RSGVKAGCIVAAvSAELIFTRLQ---------------- 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 101 gldgtrhekrqrvealmemvsldrqlathwpheISGGQQQRVALARALA----QRPSLMLLDEPFSALDT 166
Cdd:cd03227   78 ---------------------------------LSGGEKELSALALILAlaslKPRPLYILDEIDRGLDP 114
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 11-165 5.14e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 48.24  E-value: 5.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  11 FSDVQV-------LDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGR-TLFDENSFVPA-HLRRIGF 81
Cdd:PRK10636   4 FSSLQIrrgvrvlLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNwQLAWVNQETPAlPQPALEY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  82 VPQEGALFPHLNVADNIAWGL-DG----TRHEK---------RQRVEALMEMVSLDRQLATHWPHEISGGQQQRVALARA 147
Cdd:PRK10636  84 VIDGDREYRQLEAQLHDANERnDGhaiaTIHGKldaidawtiRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQA 163

                        170
                 ....*....|....*...
gi 697052228 148 LAQRPSLMLLDEPFSALD 165
Cdd:PRK10636 164 LICRSDLLLLDEPTNHLD 181
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 134-211 4.60e-05

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 45.11  E-value: 4.60e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228 134 ISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADlLAEAGVASILVTHDQNEALSFATQVAVMRSGR 211
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAE-LAKKDKGIIIISSEMPELLGITDRILVMSNGL 468
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
34-218 5.04e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 45.12  E-value: 5.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  34 GPSGSGKTTLLRILAGFETPDTGRIVMQGRTLfDENSFvpAHLRRIGFVPQEGALFPHLNVADNIA-----WGLdgTRHE 108
Cdd:NF033858 299 GSNGCGKSTTMKMLTGLLPASEGEAWLFGQPV-DAGDI--ATRRRVGYMSQAFSLYGELTVRQNLElharlFHL--PAAE 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 109 KRQRVEALMEMVSLdRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDTGLRAMTRKATADLLAEAGVASI 188
Cdd:NF033858 374 IAARVAEMLERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIF 452

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 697052228 189 LVTHDQNEAL-----SFatqvavMRSGRFTQVGTP 218
Cdd:NF033858 453 ISTHFMNEAErcdriSL------MHAGRVLASDTP 481
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
2-193 5.46e-05

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 43.46  E-value: 5.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   2 LELTAIsKSFSDVQVLDsLNLSVapgsrTAIVGPSGSGKTTLLR-ILAGF--ETPDTGRIVMQGRTLFDENSFVPAHLRR 78
Cdd:COG0419    5 LRLENF-RSYRDTETID-FDDGL-----NLIVGPNGAGKSTILEaIRYALygKARSRSKLRSDLINVGSEEASVELEFEH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  79 IGFV-----PQ-EGALFPH---------------LNVADNIAWGLDGTRHEKRQRVEALMEMVSLDRQLATHW-----PH 132
Cdd:COG0419   78 GGKRyrierRQgEFAEFLEakpserkealkrllgLEIYEELKERLKELEEALESALEELAELQKLKQEILAQLsgldpIE 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 697052228 133 EISGGQQQRVALARALAqrpslMLLDepFSALDTGlramTRKATADLLAEAGVasilVTHD 193
Cdd:COG0419  158 TLSGGERLRLALADLLS-----LILD--FGSLDEE----RLERLLDALEELAI----ITHV 203
PLN03073 PLN03073
ABC transporter F family; Provisional
 112-229 1.03e-04

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 44.08  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 112 RVEALMEMVSLDRQLATHWPHEISGGQQQRVALARALAQRPSLMLLDEPFSALDtgLRAMTRKATadLLAEAGVASILVT 191
Cdd:PLN03073 323 RAASILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD--LHAVLWLET--YLLKWPKTFIVVS 398

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 697052228 192 HDQNEALSFATQVAVMRSGRFTQVGTPYDVYTRPVDEE 229
Cdd:PLN03073 399 HAREFLNTVVTDILHLHGQKLVTYKGDYDTFERTREEQ 436
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 16-60 8.54e-04

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 39.83  E-value: 8.54e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFeTPDTGRIVM 60
Cdd:cd01130    1 MAAFLRLAVRARKNILISGGTGSGKTTLLNALLSF-IPPDERIVT 44
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 31-58 8.70e-04

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 39.01  E-value: 8.70e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 697052228  31 AIVGPSGSGKTTLLRILA---GFETPDTGRI 58
Cdd:cd02020    3 AIDGPAGSGKSTVAKLLAkklGLPYLDTGGI 33
AAA_25 pfam13481
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
 24-192 1.53e-03

AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.


Pssm-ID: 463892 [Multi-domain]  Cd Length: 193  Bit Score: 39.29  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   24 VAPGSRTAIVGPSGSGKTTLLRILAgfetpdtgRIVMQGRTLFDENsfvpahlrrigFVPQEGA-LFphlnvadniaWGL 102
Cdd:pfam13481  30 LPAGGLGLLAGAPGTGKTTLALDLA--------AAVATGKPWLGGP-----------RVPEQGKvLY----------VSA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228  103 DGTRHEKRQRVEALMEMVSLDRQLATHW-------PHEISGGQ---QQRVALARALAQR--PSLMLLDePFSAL----DT 166
Cdd:pfam13481  81 EGPADELRRRLRAAGADLDLPARLLFLSlveslplFFLDRGGPlldADVDALEAALEEVedPDLVVID-PLARAlggdEN 159

                         170       180
                  ....*....|....*....|....*...
gi 697052228  167 GLRAMTR--KATADLLAEAGVASILVTH 192
Cdd:pfam13481 160 SNSDVGRlvKALDRLARRTGATVLLVHH 187
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 31-96 3.11e-03

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 38.56  E-value: 3.11e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 697052228   31 AIVGPSGSGKTTLLRILA---GFETPDTGRI--------VMQGRTLFDENSFVPAHLR-RIGFVPQEGALFPHLNVAD 96
Cdd:TIGR00017   6 AIDGPSGAGKSTVAKAVAeklGYAYLDSGAMyraialaaLQNRVDLTSEDALAELISHlDIRFIPTNGEVEVFLNGED 83
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
9-58 3.16e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 38.83  E-value: 3.16e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 697052228   9 KSFSDVqvldSLNLSVAPGsRTAIVGPSGSGKTTLLRILAGFETPDTGRI 58
Cdd:COG3950   12 RGFEDL----EIDFDNPPR-LTVLVGENGSGKTTLLEAIALALSGLLSRL 56
PLN03140 PLN03140
ABC transporter G family member; Provisional
 24-73 3.98e-03

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 39.06  E-value: 3.98e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 697052228   24 VAPGSRTAIVGPSGSGKTTLLRILAGFETPD---TGRIVMQGRTLfdeNSFVP 73
Cdd:PLN03140  188 IKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEITYNGYRL---NEFVP 237
COG1106 COG1106
ATPase/GTPase, AAA15 family [General function prediction only];
9-48 4.19e-03

ATPase/GTPase, AAA15 family [General function prediction only];


Pssm-ID: 440723 [Multi-domain]  Cd Length: 330  Bit Score: 38.49  E-value: 4.19e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 697052228   9 KSFSDVQVLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILA 48
Cdd:COG1106   11 RSFKDELTLSMVASGLRLLRVNLIYGANASGKSNLLEALY 50
AAA_28 pfam13521
AAA domain;
29-81 5.58e-03

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 37.24  E-value: 5.58e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 697052228   29 RTAIVGPSGSGKTTLLRILA---GFET-PDTGRIVMQGRtLFDENSFVPAHLRRIGF 81
Cdd:pfam13521   1 RIVITGGPSTGKTTLAEALAarfGYPVvPEAAREILEEL-GADGGDALPWVEDLLAF 56
PRK15177 PRK15177
Vi polysaccharide ABC transporter ATP-binding protein VexC;
16-72 5.84e-03

Vi polysaccharide ABC transporter ATP-binding protein VexC;


Pssm-ID: 185099 [Multi-domain]  Cd Length: 213  Bit Score: 37.73  E-value: 5.84e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 697052228  16 VLDSLNLSVAPGSRTAIVGPSGSGKTTLLRILAGFETPDTGRIV-MQGRTL-FDENSFV 72
Cdd:PRK15177   2 VLDKTDFVMGYHEHIGILAAPGSGKTTLTRLLCGLDAPDEGDFIgLRGDALpLGANSFI 60
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 30-118 6.40e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 37.75  E-value: 6.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228   30 TAIVGPSGSGKTTLLRILAGFETPDTGRIVMQGRTLFDENSFVPAHLRRIGFVPQEGALFPHLNVADNIAWGLdGTRHEK 109
Cdd:pfam13304   2 NVLIGPNGSGKSNLLEALRFLADFDALVIGLTDERSRNGGIGGIPSLLNGIDPKEPIEFEISEFLEDGVRYRY-GLDLER 80


                  ....*....
gi 697052228  110 RQRVEALME 118
Cdd:pfam13304  81 EDVEEKLSS 89
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 32-59 6.68e-03

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 38.22  E-value: 6.68e-03
                         10        20
                 ....*....|....*....|....*...
gi 697052228  32 IVGPSGSGKTTLLRILAGFeTPDTGRIV 59
Cdd:COG4962  187 VSGGTGSGKTTLLNALSGF-IPPDERIV 213
GguA NF040905
sugar ABC transporter ATP-binding protein;
135-213 8.59e-03

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 37.85  E-value: 8.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 697052228 135 SGGQQQRVALARALAQRPSLMLLDEPFSALDTGlramtrkatA--------DLLAEAGVASILVTHDQNEALSFATQVAV 206
Cdd:NF040905 406 SGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVG---------AkyeiytiiNELAAEGKGVIVISSELPELLGMCDRIYV 476


                 ....*..
gi 697052228 207 MRSGRFT 213
Cdd:NF040905 477 MNEGRIT 483
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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