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Conserved domains on  [gi|696580498|ref|WP_033111677|]
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carboxylesterase [Dickeya dadantii]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10787854)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  19508187|12369917|37582413

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
86-305 5.37e-59

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 192.08  E-value: 5.37e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  86 RKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTRPEDMIPVSIDDWRQVVAEQARLLQRDVDEVYLGGFSTG 165
Cdd:COG1647   15 RKGVLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGYDKVIVIGLSMG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 166 ANLALEYALEHPEIRGLALFSPAIRSNETFDFLTPLVAPFRDWLRTPRPG--SPAQLTTRYLRVPTNGLAQYYRSSLAVR 243
Cdd:COG1647   95 GLLALLLAARYPDVAGLVLLSPALKIDDPSAPLLPLLKYLARSLRGIGSDieDPEVAEYAYDRTPLRALAELQRLIREVR 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 696580498 244 RLLwrHEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNPASRLIWYGQPDSAVTS---RERVRAD 305
Cdd:COG1647  175 RDL--PKITAPTLIIQSRKDEVVPPESARYIYE-RLGSPDKELVWLEDSGHVITLdkdREEVAEE 236
 
Name Accession Description Interval E-value
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
86-305 5.37e-59

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 192.08  E-value: 5.37e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  86 RKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTRPEDMIPVSIDDWRQVVAEQARLLQRDVDEVYLGGFSTG 165
Cdd:COG1647   15 RKGVLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGYDKVIVIGLSMG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 166 ANLALEYALEHPEIRGLALFSPAIRSNETFDFLTPLVAPFRDWLRTPRPG--SPAQLTTRYLRVPTNGLAQYYRSSLAVR 243
Cdd:COG1647   95 GLLALLLAARYPDVAGLVLLSPALKIDDPSAPLLPLLKYLARSLRGIGSDieDPEVAEYAYDRTPLRALAELQRLIREVR 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 696580498 244 RLLwrHEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNPASRLIWYGQPDSAVTS---RERVRAD 305
Cdd:COG1647  175 RDL--PKITAPTLIIQSRKDEVVPPESARYIYE-RLGSPDKELVWLEDSGHVITLdkdREEVAEE 236
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 83-289 7.72e-17

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 79.18  E-value: 7.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498   83 GQPRKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTrpEDMIPVSIDDWRQVVAEQARLLQRDVDE-----V 157
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGR--SDGKRGHVPSFDDYVDDLDTFVDKIREEhpglpL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  158 YLGGFSTGANLALEYALEHPE-IRGLALFSPAIRSNETFD-----FLTPLVAPFRDWLRtPRPGSPAQLTTRYLRVptng 231
Cdd:pfam12146  79 FLLGHSMGGLIAALYALRYPDkVDGLILSAPALKIKPYLAppilkLLAKLLGKLFPRLR-VPNNLLPDSLSRDPEV---- 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 696580498  232 LAQYYRSSLAVRRLLWR----------------HEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNPASRLIWY 289
Cdd:pfam12146 154 VAAYAADPLVHGGISARtlyelldagerllrraAAITVPLLLLHGGADRVVDPAGSREFYE-RAGSTDKTLKLY 226
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 81-190 8.11e-04

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 41.42  E-value: 8.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  81 PAGQPRKGIL-LVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTrpEDMIPVSIDDWRQVVAEQARLLQRDVDE--- 156
Cdd:PLN02652 130 PAAGEMRGILiIIHGLNEHSGRYLHFAKQLTSCGFGVYAMDWIGHGG--SDGLHGYVPSLDYVVEDTEAFLEKIRSEnpg 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 696580498 157 --VYLGGFSTGANLALEYALeHPEIR----GLALFSPAIR 190
Cdd:PLN02652 208 vpCFLFGHSTGGAVVLKAAS-YPSIEdkleGIVLTSPALR 246
 
Name Accession Description Interval E-value
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
86-305 5.37e-59

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 192.08  E-value: 5.37e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  86 RKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTRPEDMIPVSIDDWRQVVAEQARLLQRDVDEVYLGGFSTG 165
Cdd:COG1647   15 RKGVLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILKAGYDKVIVIGLSMG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 166 ANLALEYALEHPEIRGLALFSPAIRSNETFDFLTPLVAPFRDWLRTPRPG--SPAQLTTRYLRVPTNGLAQYYRSSLAVR 243
Cdd:COG1647   95 GLLALLLAARYPDVAGLVLLSPALKIDDPSAPLLPLLKYLARSLRGIGSDieDPEVAEYAYDRTPLRALAELQRLIREVR 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 696580498 244 RLLwrHEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNPASRLIWYGQPDSAVTS---RERVRAD 305
Cdd:COG1647  175 RDL--PKITAPTLIIQSRKDEVVPPESARYIYE-RLGSPDKELVWLEDSGHVITLdkdREEVAEE 236
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
80-281 9.17e-22

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 92.76  E-value: 9.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  80 RPAGQPRKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHG--TRPEDMIPvSIDDWRQVVAEQARLLQRDVDE- 156
Cdd:COG2267   22 RPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGrsDGPRGHVD-SFDDYVDDLRAALDALRARPGLp 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 157 VYLGGFSTGANLALEYALEHPE-IRGLALFSPAIRSNetfdfltPLVAPFRDWLRtprpgspaqlttrylrvptnglaqy 235
Cdd:COG2267  101 VVLLGHSMGGLIALLYAARYPDrVAGLVLLAPAYRAD-------PLLGPSARWLR------------------------- 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 696580498 236 yrsSLAVRRLLWRheYDRPVLMVVAEHDSVLDARYLRQLFRTHFPN 281
Cdd:COG2267  149 ---ALRLAEALAR--IDVPVLVLHGGADRVVPPEAARRLAARLSPD 189
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 77-289 8.86e-18

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 81.59  E-value: 8.86e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  77 QETRPAGQPrkgILLVHGLGDAPGTFSDVAPVLAQqGYLVRTVLLAGHGTRPEDMIPVSIDDWRQVVAEqarLLQR-DVD 155
Cdd:COG0596   17 REAGPDGPP---VVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLAA---LLDAlGLE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 156 EVYLGGFSTGANLALEYALEHPE-IRGLALFSpairsnetfdfltPLVAPFRDWLRTPRPGSPAqlttrylrvptngLAQ 234
Cdd:COG0596   90 RVVLVGHSMGGMVALELAARHPErVAGLVLVD-------------EVLAALAEPLRRPGLAPEA-------------LAA 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 696580498 235 YYRSSLAVRRLLWRHEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNpaSRLIWY 289
Cdd:COG0596  144 LLRALARTDLRERLARITVPTLVIWGEKDPIVPPALARRLAE-LLPN--AELVVL 195
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 83-289 7.72e-17

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 79.18  E-value: 7.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498   83 GQPRKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTrpEDMIPVSIDDWRQVVAEQARLLQRDVDE-----V 157
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGR--SDGKRGHVPSFDDYVDDLDTFVDKIREEhpglpL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  158 YLGGFSTGANLALEYALEHPE-IRGLALFSPAIRSNETFD-----FLTPLVAPFRDWLRtPRPGSPAQLTTRYLRVptng 231
Cdd:pfam12146  79 FLLGHSMGGLIAALYALRYPDkVDGLILSAPALKIKPYLAppilkLLAKLLGKLFPRLR-VPNNLLPDSLSRDPEV---- 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 696580498  232 LAQYYRSSLAVRRLLWR----------------HEYDRPVLMVVAEHDSVLDARYLRQLFRtHFPNPASRLIWY 289
Cdd:pfam12146 154 VAAYAADPLVHGGISARtlyelldagerllrraAAITVPLLLLHGGADRVVDPAGSREFYE-RAGSTDKTLKLY 226
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 89-324 1.27e-12

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 67.14  E-value: 1.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498   89 ILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGtrpEDMIPVSIDDWRQ--VVAEQARLLQR-DVDEVYLGGFSTG 165
Cdd:pfam00561   3 VLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFG---KSSRPKAQDDYRTddLAEDLEYILEAlGLEKVNLVGHSMG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  166 ANLALEYALEHPE-IRGLALFSPAIRSNETFDFLTPLVAPFRDWLRTPRPGSPAQLTTRYLRVPTNGLAQYYRSSLAVRR 244
Cdd:pfam00561  80 GLIALAYAAKYPDrVKALVLLGALDPPHELDEADRFILALFPGFFDGFVADFAPNPLGRLVAKLLALLLLRLRLLKALPL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  245 L---LWRHEYDRPVLMVVAEHDSVLDARYLRQLFRTHFPN-PAsrLIWYGQPDSAVTSRERVRADRLP----EWRISQFS 316
Cdd:pfam00561 160 LnkrFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRLDePT--LIIWGDQDPLVPPQALEKLAQLFpnarLVVIPDAG 237


                  ....*...
gi 696580498  317 HMSVLFSP 324
Cdd:pfam00561 238 HFAFLEGP 245
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
79-289 1.70e-12

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 66.58  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  79 TRPAG-QPRKGILLVHGL-GDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTRPEDMIPVSIDDWRQVVAEQARLLQRDVDE 156
Cdd:COG1506   15 YLPADgKKYPVVVYVHGGpGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEVDDVLAAIDYLAARPYVDPDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 157 VYLGGFSTGANLALEYALEHPE-IRGLALFSPairsnetfdfltplVAPFRDWLRTPRpgspaQLTTRYLRVPTNGLAQY 235
Cdd:COG1506   95 IGIYGHSYGGYMALLAAARHPDrFKAAVALAG--------------VSDLRSYYGTTR-----EYTERLMGGPWEDPEAY 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 696580498 236 YRSSL--AVRRLlwrheyDRPVLMVVAEHDSVLDARYLRQLFRT-HFPNPASRLIWY 289
Cdd:COG1506  156 AARSPlaYADKL------KTPLLLIHGEADDRVPPEQAERLYEAlKKAGKPVELLVY 206
YpfH COG0400
Predicted esterase [General function prediction only];
82-189 3.36e-11

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 62.23  E-value: 3.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  82 AGQPRKGILLVHGLGDAPGTFSDVAPVLAQQGYLVrtvlLAGHGTRPEDM-------------------IPVSIDDWRQV 142
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAV----LAPRAPVPEGPggrawfdlsflegredeegLAAAAEALAAF 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 696580498 143 VAEQARLLQRDVDEVYLGGFSTGANLALEYALEHPE-IRGLALFSPAI 189
Cdd:COG0400   77 IDELEARYGIDPERIVLAGFSQGAAMALSLALRRPElLAGVVALSGYL 124
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
80-207 3.58e-09

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 56.42  E-value: 3.58e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  80 RPAGQ--PRKGILLVHG----LGDaPGTFSDVAPVLA-QQGYlvrTVLLAGHGTRPEDMIPVSIDDWRQV---VAEQARL 149
Cdd:COG0657    5 RPAGAkgPLPVVVYFHGggwvSGS-KDTHDPLARRLAaRAGA---AVVSVDYRLAPEHPFPAALEDAYAAlrwLRANAAE 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 696580498 150 LQRDVDEVYLGGFSTGANLALEYALEH-----PEIRGLALFSPAIrsnetfDF-LTPLVAPFRD 207
Cdd:COG0657   81 LGIDPDRIAVAGDSAGGHLAAALALRArdrggPRPAAQVLIYPVL------DLtASPLRADLAG 138
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 73-265 8.05e-09

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 56.08  E-value: 8.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  73 WNTPQetrPAGQPRKGILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHG---TRPEDMIPVSIDDWRQVVAEQARL 149
Cdd:COG1073   27 LYLPA---GASKKYPAVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGeseGEPREEGSPERRDARAAVDYLRTL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 150 LQRDVDEVYLGGFSTGANLALEYALEHPEIRGLALFSPairsnetFDFLTPLvapFRDWLRTPR----PGSPaqlttrYL 225
Cdd:COG1073  104 PGVDPERIGLLGISLGGGYALNAAATDPRVKAVILDSP-------FTSLEDL---AAQRAKEARgaylPGVP------YL 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 696580498 226 rvPTNGLAQYYRSSLAVRRLLwrHEYDRPVLMVVAEHDSV 265
Cdd:COG1073  168 --PNVRLASLLNDEFDPLAKI--EKISRPLLFIHGEKDEA 203
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 89-274 1.02e-06

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 49.01  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498   89 ILLVHGLGDAPGTFSDvapvLAQQGYLVRTVLLAGHGTRPEDmiPVSIDDWRQVVAEQARLlqRDVDEVYLGGFSTGANL 168
Cdd:pfam12697   1 VVLVHGAGLSAAPLAA----LLAAGVAVLAPDLPGHGSSSPP--PLDLADLADLAALLDEL--GAARPVVLVGHSLGGAV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  169 ALEyALEHPEIRGLALfSPAIRSNETFDFLTPLVAPFRDWLRTPRPGSPAQLTTRYLRVPT---------NGLAQYYRSS 239
Cdd:pfam12697  73 ALA-AAAAALVVGVLV-APLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPadaewaaalARLAALLAAL 150

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 696580498  240 LAVRRLLWRHeyDRPVLMVVAEHDSVLDARYLRQL 274
Cdd:pfam12697 151 ALLPLAAWRD--LPVPVLVLAEEDRLVPELAQRLL 183
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
80-204 5.24e-06

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 47.27  E-value: 5.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  80 RPAGQ-PRKGILLVH---GLGDApgtFSDVAPVLAQQGYLVRTV-LLAGHGTRPED---MIPVSIDDWRQVVAEQARLL- 150
Cdd:COG0412   22 RPAGGgPRPGVVVLHeifGLNPH---IRDVARRLAAAGYVVLAPdLYGRGGPGDDPdeaRALMGALDPELLAADLRAALd 98

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 151 ----QRDVDEVYLG--GFSTGANLALEYALEHPEIRGLALFSPAIRSNETFDFLTPLVAP 204
Cdd:COG0412   99 wlkaQPEVDAGRVGvvGFCFGGGLALLAAARGPDLAAAVSFYGGLPADDLLDLAARIKAP 158
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
79-278 8.60e-06

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 47.06  E-value: 8.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  79 TRPAGQPRKGILLVHGL-GD-----APGTfsdvAPVLAQQGYLVRTVLLAGHGTRPEDMiPVS-----IDDWRQVVAeqa 147
Cdd:COG0429   54 SDPPAPSKPLVVLLHGLeGSsdshyARGL----ARALYARGWDVVRLNFRGCGGEPNLL-PRLyhsgdTEDLVWVLA--- 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 148 RLLQRDVD-EVYLGGFSTGANLALEYALEH----PEIRGLALFSPAIRSNETFD-------------FLTPLVAPFRDWL 209
Cdd:COG0429  126 HLRARYPYaPLYAVGFSLGGNLLLKYLGEQgddaPPLKAAVAVSPPLDLAASADrlergfnrlyqryFLRSLKRKLRRKL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 210 RT-PRPGSPAQLT--------TRYLRVPTNG---LAQYYRSSLAVRRLlwrHEYDRPVLMVVAEHDSVLDARYLRQLFRT 277
Cdd:COG0429  206 ALfPGLIDLEALKrirtlrefDDAYTAPLHGfkdAEDYYQRASALPFL---PQIRVPTLILNAADDPFLPPECLPEAAEL 282


                 .
gi 696580498 278 H 278
Cdd:COG0429  283 N 283
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
147-204 1.04e-05

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 45.92  E-value: 1.04e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 696580498 147 ARLLQRDVDEVYLGGFSTGANLALEYALEHPEIRGLALFSPAIrSNETFDFLTPLVAP 204
Cdd:COG2945   88 DWLRAQNPLPLWLAGFSFGAYVALQLAMRLPEVEGLILVAPPV-NRYDFSFLAPCPAP 144
Abhydrolase_3 pfam07859
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 128-267 1.80e-05

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 400284 [Multi-domain]  Cd Length: 208  Bit Score: 45.28  E-value: 1.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  128 PEDMIPVSIDD------WrqvVAEQARLLQRDVDEVYLGGFSTGANLALEYALE-----HPEIRGLALFSPAirsnetfd 196
Cdd:pfam07859  41 PEHPFPAAYDDayaalrW---LAEQAAELGADPSRIAVAGDSAGGNLAAAVALRardegLPKPAGQVLIYPG-------- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  197 fltpLVAPFRDWLRTPRPGSPAQLTTRYLrvptngLAQYYRssLAVRRLLWRHEY-------D----RPVLMVVAEHDSV 265
Cdd:pfam07859 110 ----TDLRTESPSYLAREFADGPLLTRAA------MDWFWR--LYLPGADRDDPLasplfasDlsglPPALVVVAEFDPL 177


                  ..
gi 696580498  266 LD 267
Cdd:pfam07859 178 RD 179
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 89-173 1.01e-04

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 41.35  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  89 ILLVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTrpedmipvSIDDWRQVVAEQ-ARLLQR-DVDEVYLGGFSTGA 166
Cdd:COG1075    8 VVLVHGLGGSAASWAPLAPRLRAAGYPVYALNYPSTNG--------SIEDSAEQLAAFvDAVLAAtGAEKVDLVGHSMGG 79


                 ....*..
gi 696580498 167 NLALEYA 173
Cdd:COG1075   80 LVARYYL 86
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 81-190 8.11e-04

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 41.42  E-value: 8.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  81 PAGQPRKGIL-LVHGLGDAPGTFSDVAPVLAQQGYLVRTVLLAGHGTrpEDMIPVSIDDWRQVVAEQARLLQRDVDE--- 156
Cdd:PLN02652 130 PAAGEMRGILiIIHGLNEHSGRYLHFAKQLTSCGFGVYAMDWIGHGG--SDGLHGYVPSLDYVVEDTEAFLEKIRSEnpg 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 696580498 157 --VYLGGFSTGANLALEYALeHPEIR----GLALFSPAIR 190
Cdd:PLN02652 208 vpCFLFGHSTGGAVVLKAAS-YPSIEdkleGIVLTSPALR 246
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
26-288 9.42e-04

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 40.86  E-value: 9.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498  26 LPTLTACGrSTTPPLGQSSFADYQQQTEQWVRQHRAfqsgdtrQELSW-----NTPQETRPAGQPRKGILLVHGLGDAPG 100
Cdd:COG4188    5 LALLLAAA-AAASPLRQPGPFAVGVQTLTLRDPSRD-------RPLPVdvwypATAPADAPAGGPFPLVVLSHGLGGSRE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 101 TFSDVAPVLAQQGYLVrtVLLAGHGTRPEDMIPV--------SIDDWRQVVAEQARLLQR---------------DVDEV 157
Cdd:COG4188   77 GYAYLAEHLASHGYVV--AAPDHPGSNAADLSAAldgladalDPEELWERPLDLSFVLDQllalnksdpplagrlDLDRI 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580498 158 YLGGFSTGANLALEYALEHPEIRGLALFSPAirsNETFDFLTPLVAPFRDWLRTPR--------PGSPAQLTtrylrvpT 229
Cdd:COG4188  155 GVIGHSLGGYTALALAGARLDFAALRQYCGK---NPDLQCRALDLPRLAYDLRDPRikavvalaPGGSGLFG-------E 224

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 696580498 230 NGLAQyyrsslavrrllwrheYDRPVLMVVAEHDSVLDARYLRQLFRTHFPNPASRLIW 288
Cdd:COG4188  225 EGLAA----------------ITIPVLLVAGSADDVTPAPDEQIRPFDLLPGADKYLLT 267
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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