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MULTISPECIES: malate synthase G [Pseudomonas]
Protein Classification
malate synthase G ( domain architecture ID 10011891 )
malate synthase G catalyzes the formation of malate from glyoxylate and acetyl-CoA
List of domain hits
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-724
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1624.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 1 MTE H VQVGGLQVA K VL F DFVNNEA I PGTG IT AD Q FWAG ADKVI HDLAPKN K ALLAKRD DF QA R ID T WH QT H A G QA HD PV A 80
Cdd:PRK02999 1 MTE R VQVGGLQVA A VL Y DFVNNEA L PGTG VD AD A FWAG FAAIV HDLAPKN R ALLAKRD EL QA K ID A WH RA H P G PP HD LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 81 YKAFL QD IGYL L PE AA DF EAS T Q NVD D EIA RM AGPQLVVPVMNAR F ALNA S NARWGSLYDALYGTDAI S E AN GAEKGKGY 160
Cdd:PRK02999 81 YKAFL TE IGYL V PE PE DF TIT T E NVD P EIA TQ AGPQLVVPVMNAR Y ALNA A NARWGSLYDALYGTDAI P E EG GAEKGKGY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 161 N K VRG D KVIA F ARAFLDEAAPL SA GSH V D S TGY KIV DG K L I V S LK G GS NS GL R D D AQ LI G F QG P AA E P I AILLK H NGLH F 240
Cdd:PRK02999 161 N P VRG A KVIA Y ARAFLDEAAPL AS GSH A D V TGY AVE DG Q L V V T LK D GS ET GL A D P AQ FV G Y QG D AA A P S AILLK N NGLH I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 241 EIQID AST P V G Q TD A AGVKDV LM E A ALTTIMDCEDSVAAVDA D DKV VI YRNWLGLMKGDL A EE VA KGG Q TFTR TM NPDR V 320
Cdd:PRK02999 241 EIQID RNH P I G K TD P AGVKDV VL E S ALTTIMDCEDSVAAVDA E DKV LV YRNWLGLMKGDL T EE FE KGG K TFTR RL NPDR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 321 YT GV DG SDV TLHGRSLLFVRNVGHLMT ID AILD K DGNE V PEGILD GLI TSL A A I H S L N GN NT R K NSRTGSVYIVKPKMHG 400
Cdd:PRK02999 321 YT AP DG GEL TLHGRSLLFVRNVGHLMT NP AILD A DGNE I PEGILD AVV TSL I A L H D L K GN GR R R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 401 PEE A AF T NELFGR I E EV L N L A RNTLKVGIMDEERRT T VNLKACI K AA SE RVVFINTGFLDRTGDEIHTSMEAG A MVRK AA 480
Cdd:PRK02999 401 PEE V AF A NELFGR V E DL L G L P RNTLKVGIMDEERRT S VNLKACI R AA KD RVVFINTGFLDRTGDEIHTSMEAG P MVRK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 481 MK AEK WI G AYE NW NVDIGL ST GL Q GRAQIGKGMWAMPDLMA A MLEQKIAHP L AGANTAWVPSPTAA A LHALHYH K VDVFA 560
Cdd:PRK02999 481 MK SSP WI A AYE DN NVDIGL AC GL R GRAQIGKGMWAMPDLMA D MLEQKIAHP K AGANTAWVPSPTAA T LHALHYH Q VDVFA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 561 R QAELAK - R E RAS V DD I LTIPLA S N TD WS E EEI RN ELDNNAQGILGYVVRW I DQGVGCSKVPDI N DVGLMEDRATLRISS 639
Cdd:PRK02999 561 V QAELAK t R P RAS L DD L LTIPLA E N AN WS A EEI QQ ELDNNAQGILGYVVRW V DQGVGCSKVPDI H DVGLMEDRATLRISS 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 640 QHIANWLRHG I V N E A QVMESLKRMA P VVD R QNAGD AL YRP L APDFD SN IAFQAA VE LV IE G TK QPNGYTEP V LH R RR R E F 719
Cdd:PRK02999 641 QHIANWLRHG V V T E E QVMESLKRMA A VVD Q QNAGD PA YRP M APDFD NS IAFQAA CD LV FK G RE QPNGYTEP L LH A RR L E A 720
....*
gi 696319574 720 KAK NG 724
Cdd:PRK02999 721 KAK QA 725
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-724
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1624.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 1 MTE H VQVGGLQVA K VL F DFVNNEA I PGTG IT AD Q FWAG ADKVI HDLAPKN K ALLAKRD DF QA R ID T WH QT H A G QA HD PV A 80
Cdd:PRK02999 1 MTE R VQVGGLQVA A VL Y DFVNNEA L PGTG VD AD A FWAG FAAIV HDLAPKN R ALLAKRD EL QA K ID A WH RA H P G PP HD LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 81 YKAFL QD IGYL L PE AA DF EAS T Q NVD D EIA RM AGPQLVVPVMNAR F ALNA S NARWGSLYDALYGTDAI S E AN GAEKGKGY 160
Cdd:PRK02999 81 YKAFL TE IGYL V PE PE DF TIT T E NVD P EIA TQ AGPQLVVPVMNAR Y ALNA A NARWGSLYDALYGTDAI P E EG GAEKGKGY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 161 N K VRG D KVIA F ARAFLDEAAPL SA GSH V D S TGY KIV DG K L I V S LK G GS NS GL R D D AQ LI G F QG P AA E P I AILLK H NGLH F 240
Cdd:PRK02999 161 N P VRG A KVIA Y ARAFLDEAAPL AS GSH A D V TGY AVE DG Q L V V T LK D GS ET GL A D P AQ FV G Y QG D AA A P S AILLK N NGLH I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 241 EIQID AST P V G Q TD A AGVKDV LM E A ALTTIMDCEDSVAAVDA D DKV VI YRNWLGLMKGDL A EE VA KGG Q TFTR TM NPDR V 320
Cdd:PRK02999 241 EIQID RNH P I G K TD P AGVKDV VL E S ALTTIMDCEDSVAAVDA E DKV LV YRNWLGLMKGDL T EE FE KGG K TFTR RL NPDR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 321 YT GV DG SDV TLHGRSLLFVRNVGHLMT ID AILD K DGNE V PEGILD GLI TSL A A I H S L N GN NT R K NSRTGSVYIVKPKMHG 400
Cdd:PRK02999 321 YT AP DG GEL TLHGRSLLFVRNVGHLMT NP AILD A DGNE I PEGILD AVV TSL I A L H D L K GN GR R R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 401 PEE A AF T NELFGR I E EV L N L A RNTLKVGIMDEERRT T VNLKACI K AA SE RVVFINTGFLDRTGDEIHTSMEAG A MVRK AA 480
Cdd:PRK02999 401 PEE V AF A NELFGR V E DL L G L P RNTLKVGIMDEERRT S VNLKACI R AA KD RVVFINTGFLDRTGDEIHTSMEAG P MVRK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 481 MK AEK WI G AYE NW NVDIGL ST GL Q GRAQIGKGMWAMPDLMA A MLEQKIAHP L AGANTAWVPSPTAA A LHALHYH K VDVFA 560
Cdd:PRK02999 481 MK SSP WI A AYE DN NVDIGL AC GL R GRAQIGKGMWAMPDLMA D MLEQKIAHP K AGANTAWVPSPTAA T LHALHYH Q VDVFA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 561 R QAELAK - R E RAS V DD I LTIPLA S N TD WS E EEI RN ELDNNAQGILGYVVRW I DQGVGCSKVPDI N DVGLMEDRATLRISS 639
Cdd:PRK02999 561 V QAELAK t R P RAS L DD L LTIPLA E N AN WS A EEI QQ ELDNNAQGILGYVVRW V DQGVGCSKVPDI H DVGLMEDRATLRISS 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 640 QHIANWLRHG I V N E A QVMESLKRMA P VVD R QNAGD AL YRP L APDFD SN IAFQAA VE LV IE G TK QPNGYTEP V LH R RR R E F 719
Cdd:PRK02999 641 QHIANWLRHG V V T E E QVMESLKRMA A VVD Q QNAGD PA YRP M APDFD NS IAFQAA CD LV FK G RE QPNGYTEP L LH A RR L E A 720
....*
gi 696319574 720 KAK NG 724
Cdd:PRK02999 721 KAK QA 725
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-720
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1369.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 9 G L Q VA KV L F DFVN N EA I PGTGI T AD Q FWAG A D KVI HDL A P K N K ALLAKRD DF QA R ID T WH QTHA G QAH D PV AYK A FL QD I 88
Cdd:cd00728 1 N L R VA GC L Y DFVN E EA L PGTGI D AD A FWAG F D EIV HDL T P R N R ALLAKRD EL QA K ID D WH RDNP G PPL D QA AYK K FL KE I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 89 GYL L PE A ADF EAS T Q NVDDEIA RM AGPQLVVP V MNAR F ALNA S NARWGSLYDALYGTD A I S E A NGAE K GKGYN K VRG D KV 168
Cdd:cd00728 81 GYL V PE P ADF TIT T D NVDDEIA TQ AGPQLVVP L MNAR Y ALNA A NARWGSLYDALYGTD V I P E E NGAE R GKGYN P VRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 169 IA F AR A FLDE AA PL SA GSH V D S TGYK I VDG K L I V S L KG G SNSG L R D D AQ LI G FQ G P A AE P I A I LLKHNGLH F EIQID AST 248
Cdd:cd00728 161 IA Y AR R FLDE SV PL TN GSH A D A TGYK V VDG Q L V V T L DD G KTTT L K D P AQ FV G YR G D A NA P S A V LLKHNGLH I EIQID RNH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 249 PV G Q TD A AGVKDV LM EAALTTIMDCEDSVAAVDA D DKV VI YRNWLGLMKGDLAEEV A K G G Q TFTR TM N P DR V YT GV DG SD 328
Cdd:cd00728 241 QI G K TD P AGVKDV VV EAALTTIMDCEDSVAAVDA E DKV LV YRNWLGLMKGDLAEEV E K N G R TFTR KL N A DR N YT TP DG GE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 329 V TL H GRSL L FVRNVGHLMT I DAILD K DGNEVPEGI L D GL ITSL A A I H S L N GN NTRK NSRTGS V YIVKPKMHGPEE A AF T N 408
Cdd:cd00728 321 I TL P GRSL M FVRNVGHLMT N DAILD S DGNEVPEGI M D AV ITSL I A L H D L K GN SAFG NSRTGS I YIVKPKMHGPEE V AF A N 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 409 ELF G R I E EV L N L AR NT L K V GIMDEERRT T VNLK A CI K AA SE RVVFINTGFLDRTGDEIHTSMEAG A M V RKA A MK AEK WIG 488
Cdd:cd00728 401 ELF S R V E DL L G L PQ NT I K M GIMDEERRT S VNLK E CI R AA RD RVVFINTGFLDRTGDEIHTSMEAG P M A RKA D MK SSP WIG 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 489 AYE NW NVDIGL ST GL Q G R AQIGKGMWAMPDLMA A M L EQKIAHP L AGANTAWVPSPTAA A LHALHYH K V D VFA R Q A ELAKR 568
Cdd:cd00728 481 AYE DN NVDIGL AA GL S G K AQIGKGMWAMPDLMA D M M EQKIAHP K AGANTAWVPSPTAA T LHALHYH Q V N VFA V Q K ELAKR 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 569 ER A SV DD I LTIPLA S N TD WS EE EI RN ELDNN A QGILGYVVRW I DQG V GCSKVPDIN D VGLMEDRATLRISSQHIANWLRH 648
Cdd:cd00728 561 RP A DL DD L LTIPLA E N AN WS PQ EI QS ELDNN V QGILGYVVRW V DQG I GCSKVPDIN N VGLMEDRATLRISSQHIANWLRH 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 696319574 649 GI VNEA QV M ESL K RMA P VVD R QNAGD AL YRP L APDFD SN IAF Q AA VE L VIE G TK QPNGYTEP V LH R RR R E F K 720
Cdd:cd00728 641 GI CTKE QV Q ESL E RMA K VVD Q QNAGD PS YRP M APDFD DS IAF K AA CD L IFQ G KE QPNGYTEP L LH A RR L E K K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
3-723
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1140.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 3 EHVQV G G LQVA KV L FD FV NN E AI PGTG IT A DQ FW A G A D KVI HDLAP K N KA LLA K RD DF QA R ID T WH QTHA G QA h D PV AYK 82
Cdd:TIGR01345 1 QTITQ G R LQVA AN L KR FV DE E VL PGTG LD A AA FW S G F D EIV HDLAP E N RQ LLA E RD EI QA A ID E WH RSNP G PI - D KA AYK 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 83 A FL QD IGYL L P EAADFEAS T Q NVD D EI ARM AGPQLVVP V MNAR F ALNA S NARWGSLYDALYG TDA I S E AN G A EKGK G YN K 162
Cdd:TIGR01345 80 S FL RE IGYL V P QPERVTIE T T NVD S EI TSQ AGPQLVVP A MNAR Y ALNA A NARWGSLYDALYG SNI I P E ED G M EKGK E YN P 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 163 V RG D KVIA FA R A FLDE AA PL SA GSH V D STG YKIVD GK L IVS LK G G SNSG L RDD AQ LI G FQ G P AA E P IA ILLK H NGLH F E I 242
Cdd:TIGR01345 160 Q RG E KVIA WV R R FLDE SL PL EN GSH Q D VVA YKIVD KQ L RIQ LK N G KETR L KTP AQ FV G YR G D AA D P TC ILLK N NGLH I E L 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 243 QIDA ST P V G QT D A A GV KD VLM E A A L TTIMDCEDSVAAVDA D DK VVI YRNWLGLM K G D L A E EVA K G G QTFT R TM N P DR V YT 322
Cdd:TIGR01345 240 QIDA NH P I G KD D P A HI KD IVL E S A I TTIMDCEDSVAAVDA E DK ILL YRNWLGLM Q G T L Q E KME K N G RQIV R KL N D DR H YT 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 323 GVD GS DVT LHGRSLLFVRNVGHLMTI DA I L D KD G N E V PEGILDG LI T SLA A IHS L NGN N TRK NSR T GSVYIVKPKMHGPE 402
Cdd:TIGR01345 320 AAN GS EIS LHGRSLLFVRNVGHLMTI PV I W D SE G E E I PEGILDG VM T GAI A LYD L KVQ N KMR NSR K GSVYIVKPKMHGPE 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 403 E A AF T N E LF G RIE EV L N LAR N TLK V G I MDEERRT TV NL K ACI KAASE RV V FINTGFLDRTGDEIHTSMEAG A M V RK AA MK 482
Cdd:TIGR01345 400 E V AF A N K LF T RIE DM L G LAR H TLK M G V MDEERRT SL NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSMEAG P M L RK ND MK 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 483 AEK WI G AYE NW NV DI GL ST GL Q G R AQIGKGMWAMPDLMA A M L EQK IAHPL AGANTAWVPSPTAA A LHALHYH KVD V FAR Q 562
Cdd:TIGR01345 480 STP WI K AYE RN NV LA GL FC GL R G K AQIGKGMWAMPDLMA E M Y EQK GDQLR AGANTAWVPSPTAA T LHALHYH QTN V QSV Q 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 563 A E LA KR E R - A SV DDILTIP L A S NT D WS E EEI RN ELDNN A QGILGYVVRW ID QG V GCSKVPDI ND V G LMEDRATLRISSQH 641
Cdd:TIGR01345 560 A N LA QT E F n A EL DDILTIP V A E NT N WS A EEI QQ ELDNN V QGILGYVVRW VE QG I GCSKVPDI HN V A LMEDRATLRISSQH 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 642 IANWLRHGIV NEA QV ME SL K RMA P VVD R QNAGD AL YRP L A PD F DSNI AFQAA VE L VIE GTKQP N GYTEP V LH R RR R EFK A 721
Cdd:TIGR01345 640 IANWLRHGIV SKE QV QA SL E RMA K VVD Q QNAGD PA YRP M A GN F ANSC AFQAA SD L IFL GTKQP S GYTEP I LH A RR L EFK E 719
..
gi 696319574 722 K N 723
Cdd:TIGR01345 720 K H 721
Malate_synthase
pfam01274 Malate synthase;
18-697
1.09e-171
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 502.69
E-value: 1.09e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 18 DFV NNEAI PGTGI TADQFWAGADKVIH D LA P KNKA LLA K RD DF QARID TW H QTH agqahdpvayka FL QDI GY LL P EAAD 97
Cdd:pfam01274 2 DFV GPYVL PGTGI LTKEALSFVAELHR D FT P RRRE LLA R RD ER QARID AG H LPD ------------ FL PET GY IR P DPDW 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 98 FE A S tqnvddeiarmagpqlvvpvmnarfalnasnarwgslydalygtdaiseangaekgkgynkvrgdkviafarafld 177
Cdd:pfam01274 70 KT A T ---------------------------------------------------------------------------- 73
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 178 eaaplsagshvdstgykivdgklivslkggsnsglrddaqligfqgpaaepiaillkhng LH F E I Q IDASTPV G QT D AAG 257
Cdd:pfam01274 74 ------------------------------------------------------------ LH P E L Q DRRVEIT G PA D RKM 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 258 VKDV L MEA A L TT IM D C EDSVA A vdaddkvviyr N W LG L MK G D L AEEV A KG G QTFT R TM N PDRV Y TGV DG sdvt LHGR SL L 337
Cdd:pfam01274 94 IINA L NSG A I TT MA D F EDSVA P ----------- T W NN L IQ G Q L NLYD A VR G RIDF R DL N AGKS Y KLN DG ---- LHGR AT L 158
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 338 FVR NV G HLMTIDA IL d K DG NEV P E GI L D G lit S L AAI H slng N NTRK NSR T G SV Y IVK PKM HGPE EAA FT N EL F G R I E EV 417
Cdd:pfam01274 159 FVR PR G WHLPEKH IL - V DG EPI P G GI F D F --- G L YFF H ---- N AKEL NSR G G GP Y FYL PKM EHHQ EAA LW N DV F N R A E DY 230
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 418 L NLA R N T LKVGIMD E ERRTTVNLKAC I KAASERVVFI N T G FL D RTGDE I H T SME A GA MV --- RKA AMKAEKWIG AYE NWN 494
Cdd:pfam01274 231 L GIP R G T IRATVLI E TLPASFQMDEI I YELRDHSAGL N C G RW D YIFSY I K T LRN A PD MV lpd RKA VTMTAPFMR AYE KLL 310
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 495 VDI ------ GLST G LQGRAQ I GKG M W A MPDL M AAMLEQ K IAHPL AG ANTA WV PS P TA A A L H A LHY H K V D V FAR Q A ELA KR 568
Cdd:pfam01274 311 IKT chkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREVR AG HDGT WV AH P GL A P L A A EVF H Q V M V RPN Q I ELA RE 390
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 569 E - RASV DD I LTIP LA sntdwse EE IRNE L D NN A Q GI L G YV VR W I d Q G V GC sk VP D I N dvg LMED R AT LR IS S Q HIAN WLR 647
Cdd:pfam01274 391 E d SITA DD L LTIP DG ------- EE TEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I I H --- LMED A AT AE IS R Q QLWQ WLR 457
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 696319574 648 HG IVNEAQ V MES L KR MA PV VD RQ NA ------- GD AL YR P --------- L A PDF D SNIAFQ A AVE L V 697
Cdd:pfam01274 458 HG VTLDEG V RVT L EL MA KL VD EE NA rlakerf GD GA YR D aarlflqqa T A EEY D DFLTLL A YDD L I 523
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
567-651
4.47e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 40.09
E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 567 K RE RA SV -- D D I L TI P LASN T dws E EEI RN eld N NAQ GI L g Y VVR W I d Q G V G C sk VP d I N dv G LMED R AT LR IS - SQ h IA 643
Cdd:COG2225 391 L RE DV SV ta A D L L DV P EGTI T --- E AGL RN --- N ISV GI Q - Y LEA W L - R G N G A -- VP - I Y -- N LMED A AT AE IS r SQ - VW 456
....*...
gi 696319574 644 N W LR HG IV 651
Cdd:COG2225 457 Q W IH HG AT 464
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-724
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1624.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 1 MTE H VQVGGLQVA K VL F DFVNNEA I PGTG IT AD Q FWAG ADKVI HDLAPKN K ALLAKRD DF QA R ID T WH QT H A G QA HD PV A 80
Cdd:PRK02999 1 MTE R VQVGGLQVA A VL Y DFVNNEA L PGTG VD AD A FWAG FAAIV HDLAPKN R ALLAKRD EL QA K ID A WH RA H P G PP HD LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 81 YKAFL QD IGYL L PE AA DF EAS T Q NVD D EIA RM AGPQLVVPVMNAR F ALNA S NARWGSLYDALYGTDAI S E AN GAEKGKGY 160
Cdd:PRK02999 81 YKAFL TE IGYL V PE PE DF TIT T E NVD P EIA TQ AGPQLVVPVMNAR Y ALNA A NARWGSLYDALYGTDAI P E EG GAEKGKGY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 161 N K VRG D KVIA F ARAFLDEAAPL SA GSH V D S TGY KIV DG K L I V S LK G GS NS GL R D D AQ LI G F QG P AA E P I AILLK H NGLH F 240
Cdd:PRK02999 161 N P VRG A KVIA Y ARAFLDEAAPL AS GSH A D V TGY AVE DG Q L V V T LK D GS ET GL A D P AQ FV G Y QG D AA A P S AILLK N NGLH I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 241 EIQID AST P V G Q TD A AGVKDV LM E A ALTTIMDCEDSVAAVDA D DKV VI YRNWLGLMKGDL A EE VA KGG Q TFTR TM NPDR V 320
Cdd:PRK02999 241 EIQID RNH P I G K TD P AGVKDV VL E S ALTTIMDCEDSVAAVDA E DKV LV YRNWLGLMKGDL T EE FE KGG K TFTR RL NPDR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 321 YT GV DG SDV TLHGRSLLFVRNVGHLMT ID AILD K DGNE V PEGILD GLI TSL A A I H S L N GN NT R K NSRTGSVYIVKPKMHG 400
Cdd:PRK02999 321 YT AP DG GEL TLHGRSLLFVRNVGHLMT NP AILD A DGNE I PEGILD AVV TSL I A L H D L K GN GR R R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 401 PEE A AF T NELFGR I E EV L N L A RNTLKVGIMDEERRT T VNLKACI K AA SE RVVFINTGFLDRTGDEIHTSMEAG A MVRK AA 480
Cdd:PRK02999 401 PEE V AF A NELFGR V E DL L G L P RNTLKVGIMDEERRT S VNLKACI R AA KD RVVFINTGFLDRTGDEIHTSMEAG P MVRK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 481 MK AEK WI G AYE NW NVDIGL ST GL Q GRAQIGKGMWAMPDLMA A MLEQKIAHP L AGANTAWVPSPTAA A LHALHYH K VDVFA 560
Cdd:PRK02999 481 MK SSP WI A AYE DN NVDIGL AC GL R GRAQIGKGMWAMPDLMA D MLEQKIAHP K AGANTAWVPSPTAA T LHALHYH Q VDVFA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 561 R QAELAK - R E RAS V DD I LTIPLA S N TD WS E EEI RN ELDNNAQGILGYVVRW I DQGVGCSKVPDI N DVGLMEDRATLRISS 639
Cdd:PRK02999 561 V QAELAK t R P RAS L DD L LTIPLA E N AN WS A EEI QQ ELDNNAQGILGYVVRW V DQGVGCSKVPDI H DVGLMEDRATLRISS 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 640 QHIANWLRHG I V N E A QVMESLKRMA P VVD R QNAGD AL YRP L APDFD SN IAFQAA VE LV IE G TK QPNGYTEP V LH R RR R E F 719
Cdd:PRK02999 641 QHIANWLRHG V V T E E QVMESLKRMA A VVD Q QNAGD PA YRP M APDFD NS IAFQAA CD LV FK G RE QPNGYTEP L LH A RR L E A 720
....*
gi 696319574 720 KAK NG 724
Cdd:PRK02999 721 KAK QA 725
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-720
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1369.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 9 G L Q VA KV L F DFVN N EA I PGTGI T AD Q FWAG A D KVI HDL A P K N K ALLAKRD DF QA R ID T WH QTHA G QAH D PV AYK A FL QD I 88
Cdd:cd00728 1 N L R VA GC L Y DFVN E EA L PGTGI D AD A FWAG F D EIV HDL T P R N R ALLAKRD EL QA K ID D WH RDNP G PPL D QA AYK K FL KE I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 89 GYL L PE A ADF EAS T Q NVDDEIA RM AGPQLVVP V MNAR F ALNA S NARWGSLYDALYGTD A I S E A NGAE K GKGYN K VRG D KV 168
Cdd:cd00728 81 GYL V PE P ADF TIT T D NVDDEIA TQ AGPQLVVP L MNAR Y ALNA A NARWGSLYDALYGTD V I P E E NGAE R GKGYN P VRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 169 IA F AR A FLDE AA PL SA GSH V D S TGYK I VDG K L I V S L KG G SNSG L R D D AQ LI G FQ G P A AE P I A I LLKHNGLH F EIQID AST 248
Cdd:cd00728 161 IA Y AR R FLDE SV PL TN GSH A D A TGYK V VDG Q L V V T L DD G KTTT L K D P AQ FV G YR G D A NA P S A V LLKHNGLH I EIQID RNH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 249 PV G Q TD A AGVKDV LM EAALTTIMDCEDSVAAVDA D DKV VI YRNWLGLMKGDLAEEV A K G G Q TFTR TM N P DR V YT GV DG SD 328
Cdd:cd00728 241 QI G K TD P AGVKDV VV EAALTTIMDCEDSVAAVDA E DKV LV YRNWLGLMKGDLAEEV E K N G R TFTR KL N A DR N YT TP DG GE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 329 V TL H GRSL L FVRNVGHLMT I DAILD K DGNEVPEGI L D GL ITSL A A I H S L N GN NTRK NSRTGS V YIVKPKMHGPEE A AF T N 408
Cdd:cd00728 321 I TL P GRSL M FVRNVGHLMT N DAILD S DGNEVPEGI M D AV ITSL I A L H D L K GN SAFG NSRTGS I YIVKPKMHGPEE V AF A N 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 409 ELF G R I E EV L N L AR NT L K V GIMDEERRT T VNLK A CI K AA SE RVVFINTGFLDRTGDEIHTSMEAG A M V RKA A MK AEK WIG 488
Cdd:cd00728 401 ELF S R V E DL L G L PQ NT I K M GIMDEERRT S VNLK E CI R AA RD RVVFINTGFLDRTGDEIHTSMEAG P M A RKA D MK SSP WIG 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 489 AYE NW NVDIGL ST GL Q G R AQIGKGMWAMPDLMA A M L EQKIAHP L AGANTAWVPSPTAA A LHALHYH K V D VFA R Q A ELAKR 568
Cdd:cd00728 481 AYE DN NVDIGL AA GL S G K AQIGKGMWAMPDLMA D M M EQKIAHP K AGANTAWVPSPTAA T LHALHYH Q V N VFA V Q K ELAKR 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 569 ER A SV DD I LTIPLA S N TD WS EE EI RN ELDNN A QGILGYVVRW I DQG V GCSKVPDIN D VGLMEDRATLRISSQHIANWLRH 648
Cdd:cd00728 561 RP A DL DD L LTIPLA E N AN WS PQ EI QS ELDNN V QGILGYVVRW V DQG I GCSKVPDIN N VGLMEDRATLRISSQHIANWLRH 640
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 696319574 649 GI VNEA QV M ESL K RMA P VVD R QNAGD AL YRP L APDFD SN IAF Q AA VE L VIE G TK QPNGYTEP V LH R RR R E F K 720
Cdd:cd00728 641 GI CTKE QV Q ESL E RMA K VVD Q QNAGD PS YRP M APDFD DS IAF K AA CD L IFQ G KE QPNGYTEP L LH A RR L E K K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
3-723
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1140.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 3 EHVQV G G LQVA KV L FD FV NN E AI PGTG IT A DQ FW A G A D KVI HDLAP K N KA LLA K RD DF QA R ID T WH QTHA G QA h D PV AYK 82
Cdd:TIGR01345 1 QTITQ G R LQVA AN L KR FV DE E VL PGTG LD A AA FW S G F D EIV HDLAP E N RQ LLA E RD EI QA A ID E WH RSNP G PI - D KA AYK 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 83 A FL QD IGYL L P EAADFEAS T Q NVD D EI ARM AGPQLVVP V MNAR F ALNA S NARWGSLYDALYG TDA I S E AN G A EKGK G YN K 162
Cdd:TIGR01345 80 S FL RE IGYL V P QPERVTIE T T NVD S EI TSQ AGPQLVVP A MNAR Y ALNA A NARWGSLYDALYG SNI I P E ED G M EKGK E YN P 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 163 V RG D KVIA FA R A FLDE AA PL SA GSH V D STG YKIVD GK L IVS LK G G SNSG L RDD AQ LI G FQ G P AA E P IA ILLK H NGLH F E I 242
Cdd:TIGR01345 160 Q RG E KVIA WV R R FLDE SL PL EN GSH Q D VVA YKIVD KQ L RIQ LK N G KETR L KTP AQ FV G YR G D AA D P TC ILLK N NGLH I E L 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 243 QIDA ST P V G QT D A A GV KD VLM E A A L TTIMDCEDSVAAVDA D DK VVI YRNWLGLM K G D L A E EVA K G G QTFT R TM N P DR V YT 322
Cdd:TIGR01345 240 QIDA NH P I G KD D P A HI KD IVL E S A I TTIMDCEDSVAAVDA E DK ILL YRNWLGLM Q G T L Q E KME K N G RQIV R KL N D DR H YT 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 323 GVD GS DVT LHGRSLLFVRNVGHLMTI DA I L D KD G N E V PEGILDG LI T SLA A IHS L NGN N TRK NSR T GSVYIVKPKMHGPE 402
Cdd:TIGR01345 320 AAN GS EIS LHGRSLLFVRNVGHLMTI PV I W D SE G E E I PEGILDG VM T GAI A LYD L KVQ N KMR NSR K GSVYIVKPKMHGPE 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 403 E A AF T N E LF G RIE EV L N LAR N TLK V G I MDEERRT TV NL K ACI KAASE RV V FINTGFLDRTGDEIHTSMEAG A M V RK AA MK 482
Cdd:TIGR01345 400 E V AF A N K LF T RIE DM L G LAR H TLK M G V MDEERRT SL NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSMEAG P M L RK ND MK 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 483 AEK WI G AYE NW NV DI GL ST GL Q G R AQIGKGMWAMPDLMA A M L EQK IAHPL AGANTAWVPSPTAA A LHALHYH KVD V FAR Q 562
Cdd:TIGR01345 480 STP WI K AYE RN NV LA GL FC GL R G K AQIGKGMWAMPDLMA E M Y EQK GDQLR AGANTAWVPSPTAA T LHALHYH QTN V QSV Q 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 563 A E LA KR E R - A SV DDILTIP L A S NT D WS E EEI RN ELDNN A QGILGYVVRW ID QG V GCSKVPDI ND V G LMEDRATLRISSQH 641
Cdd:TIGR01345 560 A N LA QT E F n A EL DDILTIP V A E NT N WS A EEI QQ ELDNN V QGILGYVVRW VE QG I GCSKVPDI HN V A LMEDRATLRISSQH 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 642 IANWLRHGIV NEA QV ME SL K RMA P VVD R QNAGD AL YRP L A PD F DSNI AFQAA VE L VIE GTKQP N GYTEP V LH R RR R EFK A 721
Cdd:TIGR01345 640 IANWLRHGIV SKE QV QA SL E RMA K VVD Q QNAGD PA YRP M A GN F ANSC AFQAA SD L IFL GTKQP S GYTEP I LH A RR L EFK E 719
..
gi 696319574 722 K N 723
Cdd:TIGR01345 720 K H 721
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
35-716
0e+00
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 536.43
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 35 FW A GADKVIHDLA P KNKA LLA K RD DF QAR I D TW H qthagqahdpv A YKA FL QDIG Y L l PEAA D FEASTQ -- NV DD EIARM 112
Cdd:cd00480 1 AL A FVAELHREFN P RRRE LLA A RD ER QAR L D AG H ----------- A LPD FL PETA Y I - RRDG D WKVAPD pp DL DD RRVEI 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 113 A GPQ LVVP V M NA RFALN A snarwgslydalygtdaiseangaekgkgynkvrgdkviafarafldeaaplsagshvdstg 192
Cdd:cd00480 69 T GPQ DRKM V I NA LNSGA A -------------------------------------------------------------- 86
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 193 ykivdgklivslkggsnsglrddaqligfqgpaaepiaillkhnglhfeiqidastpvgqtdaagvkdvlmeaal TTIM D 272
Cdd:cd00480 87 --------------------------------------------------------------------------- VFMA D 91
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 273 C EDS V A AV d ADD KV VIY RN W L GLMK G DLAEEVA K G G QTFTRT mnpdrvytgvdgsdv T L H GR SL LFVR NV G HLM T IDA IL 352
Cdd:cd00480 92 F EDS S A PT - WEN KV EGQ RN L L DAVR G TISFTDS K N G KSYRLN --------------- L L D GR AT LFVR PR G WHL T EKH IL 155
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 353 D k DG NE VP E G IL D GLITSLAAI H S L NG nntrkns R TGSV Y IVK PKM HG P E EA AFT N EL F G R I E EV L N L A R N T L K VGIMD E 432
Cdd:cd00480 156 V - DG EP VP G G LF D FGLYFFHNA H A L KA ------- R GSGP Y FYL PKM ES P L EA RLW N DV F S R A E DY L G L P R G T I K ATVLI E 227
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 433 ERRTTVNLKACIKAASERVVFI N T G FL D RTGD EI H T SM ---- EAGAMVR K AA M k AEKWIG AYE NWN V DIGLST G L ---- Q 504
Cdd:cd00480 228 TLPAAFEMDEILYELRDHSAGL N C G RW D YIFS EI K T FR nhpd FVLPDRA K VT M - TSPFMR AYE KLL V KTCHRR G A hamg G 306
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 505 GR AQI G - KG MW A MPD - L MA AMLEQ K IAHPL AG ANTA WV PS P TA A A L H AL HY HKV DVFAR Q AEL a KRE RAS V -- DD I LTIP 580
Cdd:cd00480 307 MA AQI P i KG DP A ANE a A MA KVRAD K LREAK AG HDGT WV AH P GL A P L A AL VF HKV MPGPN Q LFR - KRE DVK V ta DD L LTIP 385
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 581 L A sntdw SEEEIRNE L D NN A Q GI LGYVV R W ID qgv G CSK VP D IN dvg LMED R AT LR IS SQHIAN WLRHG IVNEAQ V MES L 660
Cdd:cd00480 386 V A ----- EGDITEEG L R NN I Q VA LGYVV A W LN --- G NGA VP I IN --- LMED A AT AE IS RSQLWQ WLRHG VCLDDG V PVT L 454
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 696319574 661 KRM A PV VD RQ NA GDAL YRP la P D F DSN IAF QA A VE L VI EG T --- KQ P NGY TEP VL H RR R 716
Cdd:cd00480 455 ELV A KL VD EE NA RLPA YRP -- P N F FDS IAF KE A AD L FF EG V tae EF P EFL TEP LY H LL R 511
Malate_synthase
pfam01274 Malate synthase;
18-697
1.09e-171
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 502.69
E-value: 1.09e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 18 DFV NNEAI PGTGI TADQFWAGADKVIH D LA P KNKA LLA K RD DF QARID TW H QTH agqahdpvayka FL QDI GY LL P EAAD 97
Cdd:pfam01274 2 DFV GPYVL PGTGI LTKEALSFVAELHR D FT P RRRE LLA R RD ER QARID AG H LPD ------------ FL PET GY IR P DPDW 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 98 FE A S tqnvddeiarmagpqlvvpvmnarfalnasnarwgslydalygtdaiseangaekgkgynkvrgdkviafarafld 177
Cdd:pfam01274 70 KT A T ---------------------------------------------------------------------------- 73
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 178 eaaplsagshvdstgykivdgklivslkggsnsglrddaqligfqgpaaepiaillkhng LH F E I Q IDASTPV G QT D AAG 257
Cdd:pfam01274 74 ------------------------------------------------------------ LH P E L Q DRRVEIT G PA D RKM 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 258 VKDV L MEA A L TT IM D C EDSVA A vdaddkvviyr N W LG L MK G D L AEEV A KG G QTFT R TM N PDRV Y TGV DG sdvt LHGR SL L 337
Cdd:pfam01274 94 IINA L NSG A I TT MA D F EDSVA P ----------- T W NN L IQ G Q L NLYD A VR G RIDF R DL N AGKS Y KLN DG ---- LHGR AT L 158
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 338 FVR NV G HLMTIDA IL d K DG NEV P E GI L D G lit S L AAI H slng N NTRK NSR T G SV Y IVK PKM HGPE EAA FT N EL F G R I E EV 417
Cdd:pfam01274 159 FVR PR G WHLPEKH IL - V DG EPI P G GI F D F --- G L YFF H ---- N AKEL NSR G G GP Y FYL PKM EHHQ EAA LW N DV F N R A E DY 230
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 418 L NLA R N T LKVGIMD E ERRTTVNLKAC I KAASERVVFI N T G FL D RTGDE I H T SME A GA MV --- RKA AMKAEKWIG AYE NWN 494
Cdd:pfam01274 231 L GIP R G T IRATVLI E TLPASFQMDEI I YELRDHSAGL N C G RW D YIFSY I K T LRN A PD MV lpd RKA VTMTAPFMR AYE KLL 310
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 495 VDI ------ GLST G LQGRAQ I GKG M W A MPDL M AAMLEQ K IAHPL AG ANTA WV PS P TA A A L H A LHY H K V D V FAR Q A ELA KR 568
Cdd:pfam01274 311 IKT chkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREVR AG HDGT WV AH P GL A P L A A EVF H Q V M V RPN Q I ELA RE 390
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 569 E - RASV DD I LTIP LA sntdwse EE IRNE L D NN A Q GI L G YV VR W I d Q G V GC sk VP D I N dvg LMED R AT LR IS S Q HIAN WLR 647
Cdd:pfam01274 391 E d SITA DD L LTIP DG ------- EE TEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I I H --- LMED A AT AE IS R Q QLWQ WLR 457
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 696319574 648 HG IVNEAQ V MES L KR MA PV VD RQ NA ------- GD AL YR P --------- L A PDF D SNIAFQ A AVE L V 697
Cdd:pfam01274 458 HG VTLDEG V RVT L EL MA KL VD EE NA rlakerf GD GA YR D aarlflqqa T A EEY D DFLTLL A YDD L I 523
PRK08951
PRK08951 malate synthase; Provisional
169-337
1.23e-26
malate synthase; Provisional
Pssm-ID: 181593 [Multi-domain]
Cd Length: 190
Bit Score: 107.42
E-value: 1.23e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 169 I A F A RA FLD EAA PL SA GSH V D STG Y KIVDGK L IVSLKG GS N SGLR DDA Q LIG F Q G PAA EP I AILLK HN G L H F E IQI D AST 248
Cdd:PRK08951 38 Q A K A KQ FLD RLF PL AN GSH Q D VSS Y VVYYQH L LAFFAD GS H SGLR QPK Q FVA F N G HKS EP S AILLK DS G S H V E LTF D RHG 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 249 PV G QT D A A GVK D VLM E AAL T TIMDCEDSVAAV daddkvvi Y R N W LG L M KGD LAEEV A KGGQ tftrtmnp D RVY T GV DGSD 328
Cdd:PRK08951 118 GT G SR D L A NIE D IQL E TCT T FSQEPTENRSTA -------- M R H W IS L L KGD ESGRP A ADQE -------- D KEF T AK DGSD 181
....*....
gi 696319574 329 VT L HGRSL L 337
Cdd:PRK08951 182 YQ L KSCFS L 190
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
334-649
7.89e-05
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 45.71
E-value: 7.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 334 RSL L F VR NV G - HL ---- MTI D aildkd G NE V PEGIL D - GL I tsla AI H sl N GNNTRKNSRTGSV Y I vk PKM HGPE EA AFT 407
Cdd:cd00727 137 PAT L I VR PR G w HL pekh VLV D ------ G EP V SGSLF D f GL Y ---- FF H -- N AKALLARGSGPYF Y L -- PKM ESHL EA RLW 202
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 408 N EL F GRIEEV L N L A R N T L K VGI ---------- MDE --- E - R RTTVN L KA -------- C IK AASERVV F I --------- NT 456
Cdd:cd00727 203 N DV F VFAQDY L G L P R G T I K ATV lietlpaafe MDE ily E l R DHSAG L NC grwdyifs F IK KFRNHPD F V lpdraqvtm TV 282
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 457 G F LDRTGDE - I H T SMEA GA mvrk A AM K aekwigayenwnvdi G LS tglqgr AQI -- GKGMW A MPDLM A AMLEQ K IAHPL A 533
Cdd:cd00727 283 P F MRAYSEL l I K T CHRR GA ---- H AM G --------------- G MA ------ AQI pi KDDPA A NEAAL A KVRAD K LREAT A 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 534 G ANTA WV PS P taaalh A L HYHKVD VF A ---- RQAE L AK - RE RAS V -- D D I L TI P LASNT dw S EE EI R N eld N NAQ G IL g Y 606
Cdd:cd00727 338 G HDGT WV AH P ------ G L VPVAME VF D khmp GPNQ L DV l RE DVK V ta A D L L LV P VEGGI -- T EE GL R Q --- N ISV G LQ - Y 405
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 696319574 607 VVR W I d Q G V GC sk VP d I N dv G LMED R AT LR IS SQHIAN W L RHG 649
Cdd:cd00727 406 LAA W L - R G N GC -- VP - I Y -- N LMED A AT AE IS RAQLWQ W I RHG 442
PLN02626
PLN02626 malate synthase
520-670
3.72e-03
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 40.53
E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 520 M A AMLEQ K IAHPL AG ANTA W VPS P taaalh A L HYHKVD VF AR ------- Q AELAK R ERAS V -- D D I L TI P LASN T dwsee 590
Cdd:PLN02626 351 L A LVRKD K LREVR AG HDGT W AAH P ------ G L IPLAME VF DG hmptpnn Q QLHKR R DDVN V te A D L L QV P RGVR T ----- 419
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 591 ei RNE L DN N AQGILG Y VVR W I d Q G V G C sk VP DI N dvg LMED R AT LR IS SQHIAN W LRH G IVNEA --- Q V MESLKRMAP VV 667
Cdd:PLN02626 420 -- LEG L RL N TRVGIQ Y LAA W L - T G T G S -- VP LY N --- LMED A AT AE IS RVQNWQ W IKY G AELDG dgv G V RVTAELFGR VV 491
...
gi 696319574 668 DRQ 670
Cdd:PLN02626 492 EEE 494
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
567-651
4.47e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 40.09
E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696319574 567 K RE RA SV -- D D I L TI P LASN T dws E EEI RN eld N NAQ GI L g Y VVR W I d Q G V G C sk VP d I N dv G LMED R AT LR IS - SQ h IA 643
Cdd:COG2225 391 L RE DV SV ta A D L L DV P EGTI T --- E AGL RN --- N ISV GI Q - Y LEA W L - R G N G A -- VP - I Y -- N LMED A AT AE IS r SQ - VW 456
....*...
gi 696319574 644 N W LR HG IV 651
Cdd:COG2225 457 Q W IH HG AT 464
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
