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Conserved domains on  [gi|695777521|ref|WP_032700297|]
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MULTISPECIES: TonB-dependent siderophore receptor [Raoultella]

Protein Classification

porin family protein( domain architecture ID 229388)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OM_channels super family cl21487
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
 42-728 5.38e-125

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


The actual alignment was detected with superfamily member TIGR01783:

Pssm-ID: 473880 [Multi-domain]  Cd Length: 651  Bit Score: 386.77  E-value: 5.38e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   42 EMAQTTWVIEGQEIEQQvqGGKEFKDVLAQLIPGIDVSSQGRTNYG-MNMRGRAIVVLIDGVRLNSSRTDSRQLDAI-DP 119
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQ--QAGSLSEALQRVPGVVVGGSGGTTQFGnITIRGFGLEVDIDNVYLDGVPLLSRGNLAIvDP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  120 FNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQE--RQVDLELGGKSGFANSNDHDERVaaavsGGTDHASGRLSVAY 196
Cdd:TIGR01783  79 AMVERVEVLRGPASlLYGGSAPGGVINIVTKRPQDEpkGSVTFGAGTRSGYRTAFDLGGPL-----GADGTFRGRLNGAR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  197 QRFGGWYDGNNDALVLDNTQTGLQhsdrldvmgtgtinIDDNRQLQLVTQYYKSQGDDYGLYLGkNMSAVTGEGkayttd 276
Cdd:TIGR01783 154 QDGDSFYDGAGEETRLGATATDWQ--------------LDDRTLLRLGAYYQKERDRGGYGGLP-ASGGTSGRD------ 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  277 gLNSDRVPGTE--RHLISLQYSDADFYGQNLVSQIYYRDESLTFYPFPTLTK-GQVSSFSSskqDTDQYGAKITLNSQPL 353
Cdd:TIGR01783 213 -LSSDRYLGTSsnRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNqVQASGYSS---DGGLFGRSLTVVNVKQ 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  354 DGWDLTWGLDADHETFNANQMFFDLntsmASGGLHNESIYTTGRYPGYSITNLAPFLQSSYDLNDIFTLSGGVRYQWTEN 433
Cdd:TIGR01783 289 DRVQIDAGLDGEFETGPIEHDLLLG----VSYGQRTTNRFNNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALN 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  434 rvddfvGYAQQQDVASGKVNSADAIPGGKTDYDNflfNAGIVAHLTDRQQTWFNFSQGVELPDPGKYYGIGKYGAAVNGN 513
Cdd:TIGR01783 365 ------GVALQRILLADKWTLTLGGRYDSVDVKS---NNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG 435

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  514 YPLLSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDK-TIVVNRTDMTIDVQSDKRRIYGVE-GAVDYFFP 591
Cdd:TIGR01783 436 GYYPKGAGNSGDILEPEKGKNYELGVRYDLGDSLLATAALFRITKDnQLVQDPVNGTFSVNAGKTRNRGVElEARGYLTP 515

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  592 DSDWSTGANFNVLKSQVKSDGSWQKWDVTLASPSKATAWVGWAPDPWSLR------VQTQQVFDLSDASGNKLDGYNTVD 665
Cdd:TIGR01783 516 GLSLSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGltlgggVQYTGKAYVDGGNTGKVPSYTVVD 595

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695777521  666 FIGSYALPVGK---LTFSIENLLNEDYVTIWGQRAPllysptygssSLYEYKGRGRTFGLNYAVSF 728
Cdd:TIGR01783 596 LSVRYDLTKKKnltLALNVNNLFDRDYYTSGYRWGP----------SAYIYPGAPRTVGLSVSYDF 651
 
Name Accession Description Interval E-value
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 42-728 5.38e-125

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 386.77  E-value: 5.38e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   42 EMAQTTWVIEGQEIEQQvqGGKEFKDVLAQLIPGIDVSSQGRTNYG-MNMRGRAIVVLIDGVRLNSSRTDSRQLDAI-DP 119
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQ--QAGSLSEALQRVPGVVVGGSGGTTQFGnITIRGFGLEVDIDNVYLDGVPLLSRGNLAIvDP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  120 FNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQE--RQVDLELGGKSGFANSNDHDERVaaavsGGTDHASGRLSVAY 196
Cdd:TIGR01783  79 AMVERVEVLRGPASlLYGGSAPGGVINIVTKRPQDEpkGSVTFGAGTRSGYRTAFDLGGPL-----GADGTFRGRLNGAR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  197 QRFGGWYDGNNDALVLDNTQTGLQhsdrldvmgtgtinIDDNRQLQLVTQYYKSQGDDYGLYLGkNMSAVTGEGkayttd 276
Cdd:TIGR01783 154 QDGDSFYDGAGEETRLGATATDWQ--------------LDDRTLLRLGAYYQKERDRGGYGGLP-ASGGTSGRD------ 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  277 gLNSDRVPGTE--RHLISLQYSDADFYGQNLVSQIYYRDESLTFYPFPTLTK-GQVSSFSSskqDTDQYGAKITLNSQPL 353
Cdd:TIGR01783 213 -LSSDRYLGTSsnRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNqVQASGYSS---DGGLFGRSLTVVNVKQ 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  354 DGWDLTWGLDADHETFNANQMFFDLntsmASGGLHNESIYTTGRYPGYSITNLAPFLQSSYDLNDIFTLSGGVRYQWTEN 433
Cdd:TIGR01783 289 DRVQIDAGLDGEFETGPIEHDLLLG----VSYGQRTTNRFNNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALN 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  434 rvddfvGYAQQQDVASGKVNSADAIPGGKTDYDNflfNAGIVAHLTDRQQTWFNFSQGVELPDPGKYYGIGKYGAAVNGN 513
Cdd:TIGR01783 365 ------GVALQRILLADKWTLTLGGRYDSVDVKS---NNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG 435

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  514 YPLLSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDK-TIVVNRTDMTIDVQSDKRRIYGVE-GAVDYFFP 591
Cdd:TIGR01783 436 GYYPKGAGNSGDILEPEKGKNYELGVRYDLGDSLLATAALFRITKDnQLVQDPVNGTFSVNAGKTRNRGVElEARGYLTP 515

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  592 DSDWSTGANFNVLKSQVKSDGSWQKWDVTLASPSKATAWVGWAPDPWSLR------VQTQQVFDLSDASGNKLDGYNTVD 665
Cdd:TIGR01783 516 GLSLSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGltlgggVQYTGKAYVDGGNTGKVPSYTVVD 595

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695777521  666 FIGSYALPVGK---LTFSIENLLNEDYVTIWGQRAPllysptygssSLYEYKGRGRTFGLNYAVSF 728
Cdd:TIGR01783 596 LSVRYDLTKKKnltLALNVNNLFDRDYYTSGYRWGP----------SAYIYPGAPRTVGLSVSYDF 651
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
27-697 1.01e-87

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 289.03  E-value: 1.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  27 ENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLaQLIPGIDVSSQGRTNYGMNMRG-----RAIVVLIDG 101
Cdd:COG1629    2 EEVVVTATRTDESLQDVPGSVSVISREQLEDQ--PATDLGDLL-RRVPGVSVTSAGGGAGQISIRGfggggNRVLVLVDG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 102 VRLNSSRTDSRQLDAIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGgksgfANSNDHdERVAAA 180
Cdd:COG1629   79 VPLNDPSGGDGGLSYIDPEDIERVEVLRGPSSaLYGSGALGGVINIVTKKPKDGKGGEVSAS-----YGSYGT-YRASLS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 181 VSGGTDHASGRLSVAYQRFGGWYDGNNdalvldntqtglqhSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGDDYGLYLG 260
Cdd:COG1629  153 LSGGNGKLAYRLSASYRDSDGYRDNSD--------------SDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTL 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 261 KNMSAVTGEGKAYTTDGLNSDRVPgTERHLISLQYSDADFyGQNLVSQIYYRDESLTFYPFPTLTKGQVSSFSSSKQDTD 340
Cdd:COG1629  219 AALRPRGAMDDGTNPYSNDTDDNT-RDRYSLSLEYEHLGD-GLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNR 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 341 QYGAKITLNSQPLDG--WDLTWGLDADHETFNANQMFFDLNTSmasgglhNESIYTTGRYPGYSITNLAPFLQSSYDLND 418
Cdd:COG1629  297 TYGLELRLTYDLGFGgkHTLLVGLDYQRQDLDGSGYPLDLGSG-------SLPTLTSGADDDGTTTSLALYAQDTYKLTD 369

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 419 IFTLSGGVRYQWTENRVDDFVgyaqqqdvasgkvnSADAIPGGKTDYDNFLFNAGIVAHLTDRQQTWFNFSQGVELPDPG 498
Cdd:COG1629  370 KLTLTAGLRYDYVSYDVDDTV--------------TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFG 435

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 499 KYYGIGkygaavngnyplLSSVNVGDSPLQGIKVNSYELGWRYT--GDNLRTQLAAYYSTSDKTIV-----VNRTDMTID 571
Cdd:COG1629  436 ELYANG------------TDPYSVGNPDLKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILsvplpNDSGFSTYY 503

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 572 VQSDKRRIYGVEGAVDYfFPDSDWSTGANFNVLKSQVKSDGSWQKW----DVTLASPSKATAWVGW-APDPWSLRVQTQQ 646
Cdd:COG1629  504 TNAGKARSYGVELELSY-QLTPGLSLNASYSYTDAKFDDDTDGSADldgnRLPGVPPLTANLGLTYeFPGGWSLGLGVRY 582

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 695777521 647 VFD--LSDASGNKLD-GYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWGQRA 697
Cdd:COG1629  583 VGDryLDDANTQGAPgGYTLVDLGAGYRFGDNlTLSLGVDNLFDKKYATSLSVRA 637
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 46-728 5.54e-86

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 283.96  E-value: 5.54e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  46 TTWVIEGQEIEQQvqgGKEFKDVLAQLIPGIDVSSQGRTNY-GMNMRGRA---IVVLIDGVRLNSSRT-DSRQLDAIDPF 120
Cdd:cd01347    1 SVSVITAEDIEKQ---PATSLADLLRRIPGVSVTRGGGGGGsTISIRGFGpdrTLVLVDGLPLASSNYgRGVDLNTIPPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 121 NIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGGKS-GFANSNDHDERVAAAVSGGtDHASGRLSVAYQr 198
Cdd:cd01347   78 LIERVEVLKGPSSaLYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdNSGSSGGGGFDVSGALADD-GAFGARLYGAYR- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 199 fggwydgNNDALVLDNTQTGLQHSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGD-DYGLYLGKNMSAVTGEGKAYTTDG 277
Cdd:cd01347  156 -------DGDGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADgPGGTLPANGTGSSLGGGPSSNTNG 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 278 LNSDRVPGTERHLISLQYS-DADFYGQNLVSQIYYRDESLTFYPFPTLTK------GQVSSFSSSKQDTDQYGAKITLNS 350
Cdd:cd01347  229 DRDWDYRDRYRKRASLGLEhDLNDTGWTLRANLSYSYTDNDGDPLILNGGnnaaggDLGRSGYSSERDTTQLGFDAGLNA 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 351 QPLDG---WDLTWGLDADHETFNanqmffdlntsmasgglhnesiyttgrypgysITNLAPFLQSSYDLNDIFTLSGGVR 427
Cdd:cd01347  309 PFGTGpvaHTLTLGVEYRREELD--------------------------------EKQTALYAQDTIELTDDLTLTLGLR 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 428 YQWTENRVDDFVGyaqqqdvasgkvnsadAIPGGKTDYDNFLFNAGIVAHLTDRQQTWFNFSQGVELPDPGKYYgigkyg 507
Cdd:cd01347  357 YDHYDQDSKDTIA----------------GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY------ 414

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 508 aavnGNYPLLSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDKTIVVNRTDMTID------VQSDKRRIYG 581
Cdd:cd01347  415 ----GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLglvtvyVNGGKARIRG 490

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 582 VEGAVDYFFPDsDWSTGANFNVLKS-QVKSDGSWQKWDVTLASPSKATAWVGW--APDPWSLRVQT-----QQVFDLSDA 653
Cdd:cd01347  491 VELEASYDLTD-GLGLTGSYTYTDTeVKRTDGATTGNRLPGIPKHTANLGLDYelPDEGLTAGGGVryrgkQYADTANGN 569

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695777521 654 SGNKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWGQRApllysptygsSSLYEYKGRGRTFGLNYAVSF 728
Cdd:cd01347  570 NTVKVPGYTLVDLSASYQFTKNlTLRLGVNNLFDKDYYTSLSVRG----------SGLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 233-727 2.50e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 125.27  E-value: 2.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  233 INIDDNRQLQLVTQYYKSQGDDYGLYLGKNMSAVTGEGKAYTTDGLNSDRVPGTERHLISLQY--SDADFYGQNLVSQIY 310
Cdd:pfam00593   7 DLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYdlGDGLSWLSTLRLGLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  311 YRDESLTFYPFPTLTKGQVSSfssskQDTDQYGAKITLNSQPLDGWDLTWGLDADHETFNANQMFFDLNTSMASGGlhNE 390
Cdd:pfam00593  87 YSSLDGDYTSNSSGLSGAGDY-----LSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPY--DP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  391 SIYTTGRYPGYSITNLAPFLQSSYDLNDIFTLSGGVRYQWTENRVDDFVGYAQQqdvasgkvnsadaipgGKTDYDNFLF 470
Cdd:pfam00593 160 ANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDN----------------FSRSYSAFSP 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  471 NAGIVAHLTDRQQTWFNFSQGVELPDPGKYYGIGKYGAAVNGNYpllssvnvGDSPLQGIKVNSYELGWRYTGDNLRTQL 550
Cdd:pfam00593 224 RLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAG--------GNPDLKPETSDNYELGLKYDDGRLSLSL 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  551 AAYYSTSDKTIVVNRTDMTID------VQSDKRRIYGVEGAVDYFFPDSDWStGANFNVLKSQVKSDGSWQKWDVTLASP 624
Cdd:pfam00593 296 ALFYIDIKNLITSDPDGPGLGgtvytyTNVGKARIRGVELELSGRLWGLGLS-GGGYTYTDADDDADADDTGNPLPNVPR 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  625 SKATAWVGWAP--DPWSLR-----VQTQQVFDLSDASGNKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWgqr 696
Cdd:pfam00593 375 HTANLGLTYDFplGGWGARlgaryVGSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNlTLRLGVNNLFDKYYKRYY--- 451

                         490       500       510
                  ....*....|....*....|....*....|.
gi 695777521  697 apllyspTYGSSSLYEYKGRGRTFGLNYAVS 727
Cdd:pfam00593 452 -------SSGGGNLGGYPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 13-153 2.90e-15

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 79.54  E-value: 2.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  13 LATALPAFAAQAEEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQ-VQggkEFKDVLAQlIPGIDVSSQGRTNYGMNMR 91
Cdd:PRK10064  17 ISCAWPVLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKpVQ---NLKDVLKE-VPGVQLTNEGDNRKGVSIR 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 695777521  92 G---RAIVVLIDGVRLNSS----RTDSRQLDAIDPFNIEHIEVISGA-TSLYGGGSTGGLINIVTKK-GQQ 153
Cdd:PRK10064  93 GldsSYTLILIDGKRVNSRnavfRHNDFDLNWIPVDAIERIEVVRGPmSSLYGSDALGGVVNIITKKiGQK 163
 
Name Accession Description Interval E-value
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 42-728 5.38e-125

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 386.77  E-value: 5.38e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   42 EMAQTTWVIEGQEIEQQvqGGKEFKDVLAQLIPGIDVSSQGRTNYG-MNMRGRAIVVLIDGVRLNSSRTDSRQLDAI-DP 119
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQ--QAGSLSEALQRVPGVVVGGSGGTTQFGnITIRGFGLEVDIDNVYLDGVPLLSRGNLAIvDP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  120 FNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQE--RQVDLELGGKSGFANSNDHDERVaaavsGGTDHASGRLSVAY 196
Cdd:TIGR01783  79 AMVERVEVLRGPASlLYGGSAPGGVINIVTKRPQDEpkGSVTFGAGTRSGYRTAFDLGGPL-----GADGTFRGRLNGAR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  197 QRFGGWYDGNNDALVLDNTQTGLQhsdrldvmgtgtinIDDNRQLQLVTQYYKSQGDDYGLYLGkNMSAVTGEGkayttd 276
Cdd:TIGR01783 154 QDGDSFYDGAGEETRLGATATDWQ--------------LDDRTLLRLGAYYQKERDRGGYGGLP-ASGGTSGRD------ 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  277 gLNSDRVPGTE--RHLISLQYSDADFYGQNLVSQIYYRDESLTFYPFPTLTK-GQVSSFSSskqDTDQYGAKITLNSQPL 353
Cdd:TIGR01783 213 -LSSDRYLGTSsnRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNqVQASGYSS---DGGLFGRSLTVVNVKQ 288

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  354 DGWDLTWGLDADHETFNANQMFFDLntsmASGGLHNESIYTTGRYPGYSITNLAPFLQSSYDLNDIFTLSGGVRYQWTEN 433
Cdd:TIGR01783 289 DRVQIDAGLDGEFETGPIEHDLLLG----VSYGQRTTNRFNNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALN 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  434 rvddfvGYAQQQDVASGKVNSADAIPGGKTDYDNflfNAGIVAHLTDRQQTWFNFSQGVELPDPGKYYGIGKYGAAVNGN 513
Cdd:TIGR01783 365 ------GVALQRILLADKWTLTLGGRYDSVDVKS---NNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG 435

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  514 YPLLSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDK-TIVVNRTDMTIDVQSDKRRIYGVE-GAVDYFFP 591
Cdd:TIGR01783 436 GYYPKGAGNSGDILEPEKGKNYELGVRYDLGDSLLATAALFRITKDnQLVQDPVNGTFSVNAGKTRNRGVElEARGYLTP 515

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  592 DSDWSTGANFNVLKSQVKSDGSWQKWDVTLASPSKATAWVGWAPDPWSLR------VQTQQVFDLSDASGNKLDGYNTVD 665
Cdd:TIGR01783 516 GLSLSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGltlgggVQYTGKAYVDGGNTGKVPSYTVVD 595

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695777521  666 FIGSYALPVGK---LTFSIENLLNEDYVTIWGQRAPllysptygssSLYEYKGRGRTFGLNYAVSF 728
Cdd:TIGR01783 596 LSVRYDLTKKKnltLALNVNNLFDRDYYTSGYRWGP----------SAYIYPGAPRTVGLSVSYDF 651
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
27-697 1.01e-87

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 289.03  E-value: 1.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  27 ENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLaQLIPGIDVSSQGRTNYGMNMRG-----RAIVVLIDG 101
Cdd:COG1629    2 EEVVVTATRTDESLQDVPGSVSVISREQLEDQ--PATDLGDLL-RRVPGVSVTSAGGGAGQISIRGfggggNRVLVLVDG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 102 VRLNSSRTDSRQLDAIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGgksgfANSNDHdERVAAA 180
Cdd:COG1629   79 VPLNDPSGGDGGLSYIDPEDIERVEVLRGPSSaLYGSGALGGVINIVTKKPKDGKGGEVSAS-----YGSYGT-YRASLS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 181 VSGGTDHASGRLSVAYQRFGGWYDGNNdalvldntqtglqhSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGDDYGLYLG 260
Cdd:COG1629  153 LSGGNGKLAYRLSASYRDSDGYRDNSD--------------SDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTL 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 261 KNMSAVTGEGKAYTTDGLNSDRVPgTERHLISLQYSDADFyGQNLVSQIYYRDESLTFYPFPTLTKGQVSSFSSSKQDTD 340
Cdd:COG1629  219 AALRPRGAMDDGTNPYSNDTDDNT-RDRYSLSLEYEHLGD-GLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNR 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 341 QYGAKITLNSQPLDG--WDLTWGLDADHETFNANQMFFDLNTSmasgglhNESIYTTGRYPGYSITNLAPFLQSSYDLND 418
Cdd:COG1629  297 TYGLELRLTYDLGFGgkHTLLVGLDYQRQDLDGSGYPLDLGSG-------SLPTLTSGADDDGTTTSLALYAQDTYKLTD 369

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 419 IFTLSGGVRYQWTENRVDDFVgyaqqqdvasgkvnSADAIPGGKTDYDNFLFNAGIVAHLTDRQQTWFNFSQGVELPDPG 498
Cdd:COG1629  370 KLTLTAGLRYDYVSYDVDDTV--------------TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFG 435

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 499 KYYGIGkygaavngnyplLSSVNVGDSPLQGIKVNSYELGWRYT--GDNLRTQLAAYYSTSDKTIV-----VNRTDMTID 571
Cdd:COG1629  436 ELYANG------------TDPYSVGNPDLKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILsvplpNDSGFSTYY 503

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 572 VQSDKRRIYGVEGAVDYfFPDSDWSTGANFNVLKSQVKSDGSWQKW----DVTLASPSKATAWVGW-APDPWSLRVQTQQ 646
Cdd:COG1629  504 TNAGKARSYGVELELSY-QLTPGLSLNASYSYTDAKFDDDTDGSADldgnRLPGVPPLTANLGLTYeFPGGWSLGLGVRY 582

                        650       660       670       680       690
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 695777521 647 VFD--LSDASGNKLD-GYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWGQRA 697
Cdd:COG1629  583 VGDryLDDANTQGAPgGYTLVDLGAGYRFGDNlTLSLGVDNLFDKKYATSLSVRA 637
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 46-728 5.54e-86

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 283.96  E-value: 5.54e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  46 TTWVIEGQEIEQQvqgGKEFKDVLAQLIPGIDVSSQGRTNY-GMNMRGRA---IVVLIDGVRLNSSRT-DSRQLDAIDPF 120
Cdd:cd01347    1 SVSVITAEDIEKQ---PATSLADLLRRIPGVSVTRGGGGGGsTISIRGFGpdrTLVLVDGLPLASSNYgRGVDLNTIPPE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 121 NIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGGKS-GFANSNDHDERVAAAVSGGtDHASGRLSVAYQr 198
Cdd:cd01347   78 LIERVEVLKGPSSaLYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdNSGSSGGGGFDVSGALADD-GAFGARLYGAYR- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 199 fggwydgNNDALVLDNTQTGLQHSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGD-DYGLYLGKNMSAVTGEGKAYTTDG 277
Cdd:cd01347  156 -------DGDGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADgPGGTLPANGTGSSLGGGPSSNTNG 228

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 278 LNSDRVPGTERHLISLQYS-DADFYGQNLVSQIYYRDESLTFYPFPTLTK------GQVSSFSSSKQDTDQYGAKITLNS 350
Cdd:cd01347  229 DRDWDYRDRYRKRASLGLEhDLNDTGWTLRANLSYSYTDNDGDPLILNGGnnaaggDLGRSGYSSERDTTQLGFDAGLNA 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 351 QPLDG---WDLTWGLDADHETFNanqmffdlntsmasgglhnesiyttgrypgysITNLAPFLQSSYDLNDIFTLSGGVR 427
Cdd:cd01347  309 PFGTGpvaHTLTLGVEYRREELD--------------------------------EKQTALYAQDTIELTDDLTLTLGLR 356

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 428 YQWTENRVDDFVGyaqqqdvasgkvnsadAIPGGKTDYDNFLFNAGIVAHLTDRQQTWFNFSQGVELPDPGKYYgigkyg 507
Cdd:cd01347  357 YDHYDQDSKDTIA----------------GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY------ 414

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 508 aavnGNYPLLSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDKTIVVNRTDMTID------VQSDKRRIYG 581
Cdd:cd01347  415 ----GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPTNTGLglvtvyVNGGKARIRG 490

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 582 VEGAVDYFFPDsDWSTGANFNVLKS-QVKSDGSWQKWDVTLASPSKATAWVGW--APDPWSLRVQT-----QQVFDLSDA 653
Cdd:cd01347  491 VELEASYDLTD-GLGLTGSYTYTDTeVKRTDGATTGNRLPGIPKHTANLGLDYelPDEGLTAGGGVryrgkQYADTANGN 569

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695777521 654 SGNKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWGQRApllysptygsSSLYEYKGRGRTFGLNYAVSF 728
Cdd:cd01347  570 NTVKVPGYTLVDLSASYQFTKNlTLRLGVNNLFDKDYYTSLSVRG----------SGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 11-672 1.23e-59

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 212.02  E-value: 1.23e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  11 LLLATALPAFAAQAEEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLaQLIPGIDVSSQG--RTNYGM 88
Cdd:COG4771   12 LAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKL--GATDLADAL-RLLPGVSVTRSGgrGGSSGI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  89 NMRG---RAIVVLIDGVRLNSSRTDSR-QLDAIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELgg 163
Cdd:COG4771   89 SIRGlggDRVLVLIDGVPVNNPALGGGgDLSYIPPDDIERIEVIRGPASaLYGSDAIGGVINIITKKPTDELEGSVSL-- 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 164 ksGFANSNDHDERVAAAVSGGTDHASGRLSVAYQRFGGWYDGNNDALVLDNTQtglqhsDRLDVMGTGTINIDDNRQLQL 243
Cdd:COG4771  167 --GYGSNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGY------ERYNLNAKLGYRLSDNHRLSL 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 244 VTQYYKSQGDdyglylgknmSAVTGEGKAYTTDGLNSDRVPGTERHLISLQYSDAdfYGQNLVSQIYYRDESLTFYPFPT 323
Cdd:COG4771  239 SGGYSRQDRD----------GGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGD--LGDNLDLSLYYSRTDRDSTNGSL 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 324 LTkgqvSSFSSSKQDTDQYGAKITLNSQPLDGWDLTWGLDADHETFNANQMFFDLNtsmasgglhnesiyttgrypgYSI 403
Cdd:COG4771  307 GG----STGSFSDSDDTTYGLELDLTYPLGGNHTLTLGAEYRYDDLDSSSFLGGAD---------------------ASR 361

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 404 TNLAPFLQSSYDLNDIFTLSGGVRYQWTENrvddfvgyaqqqdvasgkvnsadaipGGKTDYDNFLFNAGIVAHLTDRQQ 483
Cdd:COG4771  362 DTYGLFAQDEWKLTDKLTLTAGLRYDYYST--------------------------FGASNYTAFSPRLGLRYDLSDNLT 415

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 484 TWFNFSQGVELPDPGKYYgigkygaavNGNYPLLSSVNVGDSPLQGIKVNSYELGWRY--TGDNLRTQLAAYYSTSDKTI 561
Cdd:COG4771  416 LRASYGRGFRAPSLAELY---------GSGTGTPGRYVLGNPDLKPETSDNYELGLEYrlGNGGLSLSLTGFYTDIKDLI 486

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 562 VVNRTDMTIDVQS-----DKRRIYGVEGAVDYFFPDsDWSTGANFNVLKSQVKSDGSwqKWDVTLASPSKATAWVGWAPD 636
Cdd:COG4771  487 VLVPVGPGPGDVLqyenvGKARTYGLELELKYRLGK-GLTLTASYTYLDSKIDDGDT--GEPLPNVPPHKANLGLDYRLP 563

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|..
gi 695777521 637 PWSL------RVQTQQVFDLSDASGNKLDGYNTVDFIGSYAL 672
Cdd:COG4771  564 KWWLlllltrYYGGRYVTPPSGRLEGYTPGYTLLDLRASYKL 605
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
6-691 3.48e-46

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 175.12  E-value: 3.48e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   6 WVLNPLLLATALPAFAAQAEEENIIVSANRTHRT-VAEMAQTTWVIEGQEIEQQVQGGkeFKDVLAQlIPGidVSSQGRT 84
Cdd:COG4772    3 RALAAALLLAAAAAAEAATTLETVVVTGSRAAEArLKDVPGSVSVVDREELENQAATS--LREVLRR-VPG--VNVQEED 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  85 NYGMNM----RG------RAIVVLIDGVRLNSSRTDSRQLD-AIDPFNIEHIEVISGATSL-YGGGSTGGLINIVTKKGQ 152
Cdd:COG4772   78 GFGLRPnigiRGlgprrsRGITLLEDGIPIAPAPYGDPAAYyFPDLERMERIEVLRGAAALrYGPQTVGGAINFVTRTIP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 153 QER--QVDLELGGKSGFansndhdeRVAAAVSGGTDHASGRLSVAYQRFGGWYDGNndalvldntqtglqHSDRLDVMGT 230
Cdd:COG4772  158 TAFggELRVTGGSFGYR--------RTHASVGGTVGNFGYLVEYSRKRGDGFRDNS--------------GFDINDFNAK 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 231 GTINIDDNRQLQLVTQYYKSQGDDYGlYLGKNMsavtgegkaYTTDGLNSDRVP---GTERHLISLQYSDADFYGQNLVS 307
Cdd:COG4772  216 LGYRLSDRQELTLKFQYYDEDANTPG-GLTDAQ---------FDADPRQSYRPAdqfDTRRTQLSLRYEHQLSDNTTLTT 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 308 QIYYRDESLTFYpFPTLTKGQVSSFSSSKQDTDQY---GAKITLNSQ-PLDGW--DLTWGLDADHETFNANQmfFDLNTS 381
Cdd:COG4772  286 TAYYNDFSRNWY-IRQNTADPNTPGLGLRGNPRGYrsyGIEPRLTHRfELGGVphTLEVGLRYHREEEDRKQ--YVNTYG 362

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 382 MASGGLH--NESIYTTgrypgysiTNLAPFLQSSYDLNDIFTLSGGVRYQWTENRVDDFVGYAQQQDVAsgkvnsadaip 459
Cdd:COG4772  363 QGRSGAGlrRDRRFSA--------DALAAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDS----------- 423

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 460 gGKTDYDNFLFNAGIVAHLTDRQQTWFNFSQGVELPDPGKyygigkygaavngnyplLSSVNVGDSPLQGIKVNSYELGW 539
Cdd:COG4772  424 -GSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGD-----------------LAYGNGGNPDLKPEKSWNYELGT 485

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 540 RYTGDN-LRTQLAAYYS-TSDKTIVVNRTDMTIDVQS--DKRRIYGVEGAVDYFFPDS---DWSTGANFNVLKSQVKS-- 610
Cdd:COG4772  486 RGRIGNgLSAEVALFYIdYDNELGSCSAAGGDRSTFTnaGETRHQGLELALDYDLLKGgglGLPLFAAYTYTDAEFTSdf 565

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 611 DGSWQKWDVTLASPSKATAWVGWAPDPWSLRVQTQQVFD--------LSDASGNKLDGYNTVDFIGSYALPVG-KLTFSI 681
Cdd:COG4772  566 GPVFAGNRLPYVPRHQLTAGLGYEHGGWTANLNGRYVSEqftdaantVADGSFGKIPSYTVLDLSASYDFGKNlSLFAGV 645

                        730
                 ....*....|
gi 695777521 682 ENLLNEDYVT 691
Cdd:COG4772  646 NNLFDKRYIA 655
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
35-728 1.90e-42

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 163.51  E-value: 1.90e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  35 RTHRTVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLaQLIPGIDVSSQGRTNYG-MNMRG--RAIVVLIDGVRLNSSRTds 111
Cdd:COG4774    1 KTDTPLLDTPQSVTVVTRELIEDQ--GATSLADAL-RNVPGVTFGAGEGGNGDsFSIRGfsASGDIYVDGLRDPGQYR-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 112 rqldaIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGGKSgfansndHDERVAAAVSGG--TDHA 188
Cdd:COG4774   76 -----RDTFNLERVEVLKGPASvLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGS-------DGQRRATLDVNGplGDDL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 189 SGRLSVAYQRFGGWYDGnndalvldntqtglQHSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGD-DYGLYLGKNMSAVT 267
Cdd:COG4774  144 AYRLNGMYRDSDSYRDG--------------VDNDRWGIAPSLTWRLGDRTRLTLDYEYQDDDRTpDYGVPAVANGRPVD 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 268 GEGKAYTtdGLNSDRVpGTERHLISLQYS---DADFYGQNLVSQIYYRDESLTFYPFPTLTKGQVS-SFSSSKQDTDQYG 343
Cdd:COG4774  210 VDRSTFY--GQPDDYS-DSETDSATLRLEhdfNDNWTLRNALRYSDYDRDYRNTYPTGGNATGTVTrSAYRRDQDNDTLS 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 344 AKITLNSQ-PLDGWDLTW--GLDADHETFNANQmfFDLNTSMASGGLHN-------ESIYTTGRYPGYSITNLAPFLQSS 413
Cdd:COG4774  287 NQTDLTGKfDTGGVKHTLlaGVEYSREDSDNAR--YSGGGTAPTVNLYNpvygapvTGPTLGGADNDSRTDTTGLYLQDT 364

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 414 YDLNDIFTLSGGVRYQWTENRVDDFVGYAQQQDvasgkvnsadaipggkTDYDNFLFNAGIVAHLTDRQQTWFNFSQgve 493
Cdd:COG4774  365 ISLTDRWSLLAGLRYDRFDTDYTDRTTGATTSS----------------YDDSAFSPRAGLVYKPTPNLSLYASYST--- 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 494 lpdpgkyygigkyGAAVNGNYPLLSSVNVGDSPLQGikvNSYELGWRYT--GDNLRTQLAAYYSTSDKTIVVNRTDMTID 571
Cdd:COG4774  426 -------------SFNPGGGAPSLSNAGQALDPEKS---RQYEVGVKWDllDGRLSLTAALFRIEKTNVRTTDPANPGVY 489

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 572 VQSDKRRIYGVEGAVdYFFPDSDWSTGANFNVLKSQVKSDGSWQ---KwDVTLASPSKATAWVGWAPDPWSLRV------ 642
Cdd:COG4774  490 VQTGEQRSRGVELEA-TGELTPGWSVLAGYTYLDAEITKSANAAnvgN-RLPNVPRHSASLWTTYDLPLPGLTLgggvry 567

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 643 QTQQVFDlsDASGNKLDGYNTVDFIGSYAL--PVgKLTFSIENLLNEDYvtiwgqrapllYSPTYGSSSLyeYKGRGRTF 720
Cdd:COG4774  568 VGSRYAD--AANTVKLPSYTRFDAGASYRLnkNL-TLRLNVNNLTDKRY-----------YASAYGSGYV--TPGAPRTV 631


                 ....*...
gi 695777521 721 GLNYAVSF 728
Cdd:COG4774  632 LLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 32-728 2.32e-33

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 136.95  E-value: 2.32e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  32 SANRTHRTVAEMAQTTWVIEGQEIE-QQVQggkEFKDVLAQlIPGI-DVSSQGRTNYGMNMRG-RAIVVLIDGVRLNSSR 108
Cdd:COG4773   54 TATKLDTPLRETPQSVSVVTRQLIEdQGAT---TLDDALRN-VPGVtVSSYDGGGRDSFSIRGfSIDNYLRDGLPLGGFG 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 109 TDSrqldaIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGgksgfANSNDHdERVAAAVSG---G 184
Cdd:COG4773  130 GGQ-----PDTANLERVEVLKGPAGlLYGAGSPGGLVNLVTKRPTAEPQGEVSLS-----AGSWDT-YRATADVGGplnE 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 185 TDHASGRLSVAYQRFGGWYDGnndalvldntqtglQHSDRLDVMGTGTINIDDNRQLQLVTQYYKSQGD-DYGLYLGKNM 263
Cdd:COG4773  199 DGTLRYRLNAAYEDGDSFRDG--------------VDNRRTLIAPSLDWDLTDDTTLTLGAEYQDDDSTgDRGFLPLDGT 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 264 SAVTGEGKAYTTDGLNSDrvpgTERHLISLQYS---DADFYGQNLVSQIYYR--DESLTFYPFPTLTKGQVS-SFSSSKQ 337
Cdd:COG4773  265 LLDLPRSTNLGEPWDYYD----TETTTLFAELEhrfNDDWSLRANARYSDSDrdGRSAYAYGAPDAATGTLTrYASARDG 340

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 338 DTDQYGAKITLNSqPLDGW----DLTWGLDADHETFNANQMF---FDLNTSmASGGLHNESIYTTGRYpgYSITNLAPFL 410
Cdd:COG4773  341 DSRSDSLDANLNG-KFETGglehTLLVGADYSRYDSDSDSATagtINIYNP-VYGNLPEPDFDASDTD--TTTRQTGLYA 416

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 411 QSSYDLNDIFTLSGGVRYQWTENRVDDFVGYAQQqdvasgkvnsadaipggKTDYDNFLFNAGIVAHLTDRQQTWFNFSQ 490
Cdd:COG4773  417 QDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTT-----------------SYDDSAFTPRAGLVYDLTPGLSLYASYSE 479

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 491 GVELPDpgkyygigkyGAAVNGNyPLlssvnvgdSPLQGikvNSYELG--WRYTGDNLRTQLAAYYSTSDKTIVVNRTDM 568
Cdd:COG4773  480 SFEPQS----------GADNNGN-PL--------DPETG---KQYEAGvkGELFDGRLNATLAVFDITQKNVATTDPDNP 537

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 569 TIDVQSDKRRIYGVE----GAvdyffPDSDWSTGANFNVLKSQVKSDGSWQKWDVTLASPSK-ATAWVGWAPDPWSL--- 640
Cdd:COG4773  538 NFYVQVGEVRSRGVElelsGE-----LTPGLNLIAGYTYTDAKITKDADALEGKRLTNVPRHtASLWTTYRFPSGALkgl 612

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 641 ------RVQTQQVFDlsDASGNKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYvtiwgqrapllYSPTYGSSSLYEy 713
Cdd:COG4773  613 glgggvRYVGERYGD--AANTFTLPSYTLVDAGARYDLGKNwTLQLNVNNLFDKKY-----------YASSGSRGYVYY- 678

                        730
                 ....*....|....*
gi 695777521 714 kGRGRTFGLNYAVSF 728
Cdd:COG4773  679 -GAPRNVRLSLSYKF 692
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 233-727 2.50e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 125.27  E-value: 2.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  233 INIDDNRQLQLVTQYYKSQGDDYGLYLGKNMSAVTGEGKAYTTDGLNSDRVPGTERHLISLQY--SDADFYGQNLVSQIY 310
Cdd:pfam00593   7 DLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYdlGDGLSWLSTLRLGLR 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  311 YRDESLTFYPFPTLTKGQVSSfssskQDTDQYGAKITLNSQPLDGWDLTWGLDADHETFNANQMFFDLNTSMASGGlhNE 390
Cdd:pfam00593  87 YSSLDGDYTSNSSGLSGAGDY-----LSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPY--DP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  391 SIYTTGRYPGYSITNLAPFLQSSYDLNDIFTLSGGVRYQWTENRVDDFVGYAQQqdvasgkvnsadaipgGKTDYDNFLF 470
Cdd:pfam00593 160 ANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDN----------------FSRSYSAFSP 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  471 NAGIVAHLTDRQQTWFNFSQGVELPDPGKYYGIGKYGAAVNGNYpllssvnvGDSPLQGIKVNSYELGWRYTGDNLRTQL 550
Cdd:pfam00593 224 RLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAG--------GNPDLKPETSDNYELGLKYDDGRLSLSL 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  551 AAYYSTSDKTIVVNRTDMTID------VQSDKRRIYGVEGAVDYFFPDSDWStGANFNVLKSQVKSDGSWQKWDVTLASP 624
Cdd:pfam00593 296 ALFYIDIKNLITSDPDGPGLGgtvytyTNVGKARIRGVELELSGRLWGLGLS-GGGYTYTDADDDADADDTGNPLPNVPR 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  625 SKATAWVGWAP--DPWSLR-----VQTQQVFDLSDASGNKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYVTIWgqr 696
Cdd:pfam00593 375 HTANLGLTYDFplGGWGARlgaryVGSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNlTLRLGVNNLFDKYYKRYY--- 451

                         490       500       510
                  ....*....|....*....|....*....|.
gi 695777521  697 apllyspTYGSSSLYEYKGRGRTFGLNYAVS 727
Cdd:pfam00593 452 -------SSGGGNLGGYPGPGRTFYLGLSYK 475
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
29-310 4.91e-29

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 116.90  E-value: 4.91e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  29 IIVSANRTHRTVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLAQLiPGIDVSSQGR--TNYGMNMRG---RAIVVLIDGVR 103
Cdd:COG4206    1 VVVTATRLEQSKSDLTGSVTVIDAEELERS--GATSLADALRRV-PGVQVSSSGGpgSAASISIRGlgsNQTLVLIDGVP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 104 LNSSRTDSRQLDAIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGGksgfanSNDHDERVAAAVS 182
Cdd:COG4206   78 LNDPSLGGVDLSLIPPDDIERIEVLKGAASaLYGSDAIGGVINITTKKGKKGFKGSVSASY------GSFGTRRLSASLS 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 183 GGTDHASGRLSVAYQRFGGWYDGNNDALVLDNTqtglqhsDRLDVMGTGTINIDDNRQLQLVTQYYKSQGDDYGLYLGKN 262
Cdd:COG4206  152 GGAGKFSYSLSASYRRSDGYRYNDPDLRNNDGY-------ENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPGAVGSDR 224

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 695777521 263 MSAVTGEGKAYTTDGLNSDRVPGTERHLISLQYSDADFYGQNLVSQIY 310
Cdd:COG4206  225 NLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARA 272
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 39-142 7.71e-18

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 79.62  E-value: 7.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   39 TVAEMAQTTWVIEGQEIEQQvqGGKEFKDVLaQLIPGIDVSSQGRTNYG-MNMRG---RAIVVLIDGVRLNSSRTDSRQL 114
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQ--GATNLADAL-RGVPGVSVSSGGGGGGSsISIRGfgsNRVLVLVDGVPLNSGGGGSVDL 77

                          90       100
                  ....*....|....*....|....*....
gi 695777521  115 DAIDPFNIEHIEVISGATS-LYGGGSTGG 142
Cdd:pfam07715  78 NSIDPEDIERVEVLKGPASaLYGSGAIGG 106
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 13-153 2.90e-15

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 79.54  E-value: 2.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  13 LATALPAFAAQAEEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQ-VQggkEFKDVLAQlIPGIDVSSQGRTNYGMNMR 91
Cdd:PRK10064  17 ISCAWPVLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKpVQ---NLKDVLKE-VPGVQLTNEGDNRKGVSIR 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 695777521  92 G---RAIVVLIDGVRLNSS----RTDSRQLDAIDPFNIEHIEVISGA-TSLYGGGSTGGLINIVTKK-GQQ 153
Cdd:PRK10064  93 GldsSYTLILIDGKRVNSRnavfRHNDFDLNWIPVDAIERIEVVRGPmSSLYGSDALGGVVNIITKKiGQK 163
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-165 1.80e-10

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 64.24  E-value: 1.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   1 MNKRlwvlNPLLLATALPAFAAQAEEEN---IIVSANRTHRTVAEMAQTTWVIEGQEIEQ-QVqggKEFKDVLAQLiPGI 76
Cdd:PRK10641   1 MIKK----ASLLTALSVTAFSGWAQDTSpdtLVVTANRFQQPVSTVLAPTTVVTRDDIDRwQS---KSVNDVLRRL-PGV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  77 DVSSQG--RTNYGMNMRG---RAIVVLIDGVRLNSSR-TDSRQLDAIDPFNIEHIEVISGATS-LYGGGSTGGLINIVTK 149
Cdd:PRK10641  73 DIAQNGglGQLSSLFIRGtnsSHVLVLIDGVRLNQAGiSGSADLSQIPISLVQRIEYIRGPRSaVYGSDAIGGVVNIITT 152

                        170
                 ....*....|....*.
gi 695777521 150 KGQQERQVDLELGGKS 165
Cdd:PRK10641 153 RDKPGTTLSAGWGSNG 168
PRK13483 PRK13483
ligand-gated channel protein;
1-163 2.78e-09

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 60.56  E-value: 2.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   1 MNKRLwvLNPLLLATALPA-FAAQAEE--------ENIIVSANRTHRTVAEMAQTTWVIEGQEIEQqvqggKEFKDVLAQ 71
Cdd:PRK13483   1 MKKYL--AQVISALCLLPAvFVTHALAqaapdktmETVVVTASGYEQQIRDAPASISVITREDLEN-----RFYRDLTDA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  72 L--IPGIDVSSQGRTNyGMNMRGRA---IVVLIDGVRLNS--SRTDSR----QLDAIDPFN-IEHIEVISGA-TSLYGGG 138
Cdd:PRK13483  74 LldVPGVVVTGGGDRT-DISLRGMGsqyTLILVDGKRQSSreTRPNSDgpgvEQAWTPPLAaIERIEVIRGPmSSLYGSD 152

                        170       180
                 ....*....|....*....|....*
gi 695777521 139 STGGLINIVTKKGQQERQVDLELGG 163
Cdd:PRK13483 153 AIGGVINIITRKVPNEWQGEVRLDT 177
PRK13513 PRK13513
ligand-gated channel protein;
14-159 1.21e-08

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 58.24  E-value: 1.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  14 ATALPAFAAQAEEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQqvqggKEFKDVLAQL--IPGIDVSSQGRTNyGMNMR 91
Cdd:PRK13513  23 AYAAEKTNTATPTDTMVVTASGFQQRIQDAPASISVVTREQLEN-----KAYRDVTDALkdVPGVVVTGGGSTS-DISIR 96

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695777521  92 GRA---IVVLIDGVRLNSSRT----DSRQLDA--IDPFN-IEHIEVISGA-TSLYGGGSTGGLINIVTKKGQQERQVDL 159
Cdd:PRK13513  97 GMAakyTLILVDGKRVDTRSTrpnsDGSGIEQgwLPPLAaIERIEVVRGPmSSLYGSDAMGGVINIITRKVQKEWHGSL 175
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-210 1.88e-08

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 57.73  E-value: 1.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   1 MNKRLWVLnPLLLATALPAFAAQAEEENIIVSANrthrtvAEMAQTTWVIEGQEIEQQVQGGKEF-KDVLAQLIPGIDVS 79
Cdd:PRK13524   1 MNKKIHSL-ALLVNLGIYGVAQAAEAEDAKTDDT------PASHEDTIVVTAAEQNLQAPGVSTItAEDIRKRPPANDVS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  80 SQGRTNYGMNMRG----------RAI----------VVLIDGVRLNS-------------SRTDSrqlDAIDPFNIEHIE 126
Cdd:PRK13524  74 EIIRTMPGVNLTGnstsgqrgnnRQIdirgmgpentLILIDGKPVSSrnsvrygwrgerdTRGDT---NWVPPEMIERIE 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 127 VISG-ATSLYGGGSTGGLINIVTKKGQQERQvdlelGGKSGFANSNDHDE-----RVAAAVSGG-TDHASGRLsvayqrF 199
Cdd:PRK13524 151 VLRGpAAARYGNGAAGGVVNIITKKPTGEWH-----GSWNTYFNAPEHKAegatkRTNFSLSGPlGDELSFRL------Y 219

                        250
                 ....*....|.
gi 695777521 200 GGWYDGNNDAL 210
Cdd:PRK13524 220 GNLNKTQADAW 230
PRK13486 PRK13486
TonB-dependent receptor;
10-150 6.59e-07

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 52.72  E-value: 6.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  10 PLLLATALPAFAAqaeEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQQvqggkEFKDVLAQL--IPGIDV-SSQGRTNy 86
Cdd:PRK13486  12 PCLGFSASSIAAA---EDVMIVSASGYEKKLTNAAASVSVISQEELQSS-----QYHDLAEALrsVEGVDVeSGTGKTG- 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 695777521  87 GMNMRGRAI-----VVLIDGVRLN-SSRTDSRQLDAID-----PFN-IEHIEVISGATS-LYGGGSTGGLINIVTKK 150
Cdd:PRK13486  83 GLEISIRGMpasytLILIDGVRQGgSSDVTPNGFSAMNtgfmpPLAaIERIEVIRGPMStLYGSDAMGGVVNIITRK 159
PRK14050 PRK14050
TonB-dependent siderophore receptor;
117-188 4.41e-06

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 50.18  E-value: 4.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 117 IDPFNIEHIEVISGATS-LYGGGSTGGLINIVTKKGQQERQVDLELGGKS------GF------ANSNDHDERVAAAVSG 183
Cdd:PRK14050 153 IDPFMLERVEVLKGPASvLYGGSNPGGIVNMVSKRPLDEPLYYTEIGINSygnaftGFdvgdklSDDGTVRYRVTGKVAG 232


                 ....*
gi 695777521 184 GTDHA 188
Cdd:PRK14050 233 GDNYS 237
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
 7-690 1.13e-05

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 48.65  E-value: 1.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   7 VLNPLLLATALPAfAAQAEEENIIVSANRTHRTVAEMA------------QTTWVIEGQEIEQQvqGGKEFKDVLAQlIP 74
Cdd:PRK09840  24 GITPVAQALAAEG-QTNADDTLVVEASTPSLYAPDQSAdpkfsqpladttQTITVISEQVIKDQ--GATNLTEALRN-VP 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  75 GID---VSSQGRTNYG--MNMRG--RAIVVLIDGVR-LNS-SRtdsrqldaiDPFNIEHIEVISGATSL-YGGGSTGGLI 144
Cdd:PRK09840 100 GVGtffAGENGNTTTGdaIYMRGfdTSNSIYVDGIRdIGSiSR---------DTFNTEQVEVIKGPSGTdYGRSAPTGSI 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 145 NIVTKKGQQERQVD--LELGG---KSGFANSN---DHDERVAAAVSGGTDHASGRLSVAYQRFGgwydgnndalVLDNTQ 216
Cdd:PRK09840 171 NMISKQPRNDSGIDasASIGSawfRRGTLDVNqviGDTTAVRLNVMGEKTHDAGRDKVKNERYG----------VAPSVA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 217 TGLQHSDR--LDVMGTGTINIDDNRQLQLVTQYYKSQgdDYGLYLGKNMSAVTGE---GKAYTTDGLNSDRVPGTERHLI 291
Cdd:PRK09840 241 FGLGTANRlyLNYLHVTQNNTPDGGIPTIGLPGYSAP--SAGRAALNHAGKVDTHnfyGTDSDYDDSTTDTATMRFEHDI 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 292 S--LQYSDADFYGQnlVSQIYYrdesLTFY-----PFPTLTKGQVSSFSSSKQD----------TDQYGAKITLNSQPLd 354
Cdd:PRK09840 319 NdnTTLRNTTRWSR--VKQDYL----LTAImggasNITTPTPSDVNTWTWSRTAntkdvsnkilTNQTNLTSTFYTGSI- 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 355 GWDLTWGLDADHETfnanQMFFDLNTSMASG-GLHNESIYTTGryPGY---------SITNLAPFLQSSYDLNDIFTLSG 424
Cdd:PRK09840 392 GHDVSTGVEFTRET----QTNYGVNPVTLPAvNLYHPDSSIHP--GGLtrnganangQTDTFAIYAFDTLQLTRDWELNG 465

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 425 GVR---YQWTENRVDDFVGYAQQQDVASGKVNSADAIPGGKTDYDNFLFN--AGIVAHLTDRQQTWFNFSQGvELPDPGK 499
Cdd:PRK09840 466 GIRldnYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNwkAGALYKLTENGNVYINYAVS-QQPPGGS 544

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 500 YYGIGKYGAAVNGNYPllssvnvgdsPLQGIKVNSYELGWRYTGDNLRTQL-AAYYSTSDKTIVVNRTDMTIDvQSDKRR 578
Cdd:PRK09840 545 NFALAQSGSGNSANRT----------DFKPQKANTSEIGTKWQVLDKRLLLtAALFRTDIENEVEQNDDGTYS-QYGKKR 613

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 579 IYGVE-GAVDYFFPdsDWSTGANFNVLKSQVKS------DGSwqkwdVTLA-SPSKA-TAWvgwapdpwslrVQTQQVFD 649
Cdd:PRK09840 614 VEGYElSVAGNITP--AWQVIAGYTQQKATVKNgkdvaqDGS-----SSLPyTPEHAfTLW-----------SQYQATDD 675

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 650 LSDASG------------------NKLDGYNTVDFIGSYALPVG-KLTFSIENLLNEDYV 690
Cdd:PRK09840 676 LSVGGGaryigsmhrgsdgavgtpAFTEGYWVADAKLGYRVNRNlDLQLNVYNLFDTDYV 735
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
21-611 1.16e-05

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 48.85  E-value: 1.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  21 AAQAEEENIIVSANRTHRTVAEMAQTTWVIEGQEIEQqvqggKEFKDvLAQLIPGID-VSSQGRTNY-GMNMRGRA---I 95
Cdd:PRK13484  25 SSDKKEDTLVVTASGFTQQLRNAPASVSVITSEQLQK-----KPVSD-LVDAVKDVEgISITGGNEKpDISIRGLSgdyT 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  96 VVLIDGVRLNS--SRTD-SRQLDA--IDPFN-IEHIEVISGA-TSLYGGGSTGGLINIVTKKGQQErqvdlELGGKSGFA 168
Cdd:PRK13484  99 LILVDGRRQSGreSRPNgSGGFEAgfIPPVEaIERIEVIRGPmSSLYGSDAIGGVINIITKPVNNQ-----TWDGVLGLG 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 169 NSNDHDERVAAAVSGGTdHASGRL---SVAYQRFGGWYDGNNDALvldntQTGLQHSDRLDVMGTGTINIDDNRQLQLvt 245
Cdd:PRK13484 174 GIIQEHGKFGNSTTNDF-YLSGPLikdKLGLQLYGGMNYRKEDSI-----SQGTPAKDNKNITATLQFTPTESQKFVF-- 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 246 qYYKSQGDDYGLYLGKNMSAVTGEGKAYTTdglNSDRVPGTERHLISLQYSDAdfyGQNLVSQIYYRDESltfypfptlT 325
Cdd:PRK13484 246 -EYGKNNQVHTLTPGESLDAWTMRGNLKQP---NSKRETHNSRSHWVAAWNAQ---GEILHPEIAVYQEK---------V 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 326 KGQVSSFSSSKQDTDQY---GAKITLNSQPLDGwDLTWGLDADHETFNANQMFFDLNTSMASGGlhnesiyTTGRYPGYS 402
Cdd:PRK13484 310 IREVKSGKKDKYNHWDLnyeSRKPEITNTIIDA-KVTAFLPENVLTIGGQFQHAELRDDSATGK-------KTTETQSVS 381

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 403 ITNLAPFLQSSYDLNDIFTLSGGVryqwtenRVDDFVGYAQQQDVASGKVNSADaipggktdyDNFLFNAGIVAHLTdrq 482
Cdd:PRK13484 382 IKQKAVFIENEYAATDSLALTGGL-------RLDNHEIYGSYWNPRLYAVYNLT---------DNLTLKGGIAKAFR--- 442

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 483 qtwfnfSQGVELPDPGkyygigkYGAAVNGNypllSSVNVGDSPLQGIKVNSYELGWRYTGDNLRTQLAAYYSTSDKTIV 562
Cdd:PRK13484 443 ------APSIREVSPG-------FGTLTQGG----ASIMYGNRDLKPETSVTEEIGIIYSNDSGFSASATLFNTDFKNKL 505

                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521 563 VNRTDMTID-------VQSD---KRRIYGVEGAVDyfFPDSD-WSTGANFNVLKSQVKSD 611
Cdd:PRK13484 506 TSYDIGTKDpvtglntFIYDnvgEANIRGVELATQ--IPVYDkWHVSANYTFTDSRRKSD 563
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
 56-167 6.07e-05

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 46.29  E-value: 6.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  56 EQQVQGGKEFKDVLAqLIPGIDVSSQGRTNY--GMNMRGRAIVVL-----IDGVRLNSsrtDSRQLDAIDPFNIEHIEVI 128
Cdd:PRK10044  90 EMALHQPKSVKEALS-YTPGVSVGTRGASNTydHLIIRGFAASGQsqnnyLDGLKLQG---NFYNDAVIDPYMLERAELM 165

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 695777521 129 SGATS-LYGGGSTGGLINIVTKKGQQE--RQVDLELGGKSGF 167
Cdd:PRK10044 166 RGPVSvLYGKSNPGGLLNMVSKRPTTEplKEVQFKMGTDNLF 207
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 2-150 1.86e-04

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 44.75  E-value: 1.86e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521   2 NKRLWVLNPLLLATALPAFAAQAEEEN----IIVSAnrTHRTVAEMAQTTWVIEGQEIEQQvqggKEFKDvLAQLI---P 74
Cdd:PRK13528   6 NKILWLLTVLLVGLNSPVSAAESSDDDngetMVVEA--TAEQELKQQPGVSIITAEDIKKR----PPVND-LSDIIrkmP 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695777521  75 GIDV---SSQGR--TNYGMNMRGRA---IVVLIDGVRLNS-------------SRTDSRQLDAIDpfnIEHIEVISG-AT 132
Cdd:PRK13528  79 GVNLtgnSASGTrgNNRQIDIRGMGpenTLILIDGVPVTSrnsvryswrgerdTRGDTNWVPPEM---VERIEVIRGpAA 155

                        170
                 ....*....|....*...
gi 695777521 133 SLYGGGSTGGLINIVTKK 150
Cdd:PRK13528 156 ARYGSGAAGGVVNIITKR 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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