|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
2-696 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1131.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 2 ALTAALKAQIAAWYKALQEQIPDFIPRPPQRQMIADVAKTLAGEE---GRHLAIEAPTGVGKTLSYLIPGIAIAREQQKT 78
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 79 LVVSTANVALQDQIYSKDLPLLRKIIP-DLRFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDDLTPNNQAEQKLCA 157
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 158 TLKTDLDSYRWDGLRDHTDKPVDDALWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAME--SEA 235
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 236 VLPEPKNLLLVLDEGHHLPDVARDALEMSAEM--TAPWYRLQLDLFSKLVATCMeqfrpktTPPLANPERLSGHCEELYE 313
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIM-------EPPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 314 LIASLNAILNLYMPAG-QEAEHRFPMGELPQEVMDICQRLAKLTEMLRGLAELFLNDLGE--KTGSHDVVRLHRVLLQMN 390
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 391 RALGMFESQSKLWRLAS-LAQSSGAPVTKWVTRDMRDGQTHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFS 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 470 RLQEMSGLKEKAGDRFVALDSPFNHVEQGKIVIPQMHYEPliDNEEQHIAEMAAYFREQVESKKhlGMLVLFASGRAMQR 549
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEKHK--GSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 550 FLEHVP-DLRLLLLVQGDKPRYRLVELHRKRVEGGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGE 628
Cdd:PRK11747 550 VADLLPrDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 695765691 629 WLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALPVFPIEQPA 696
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
13-697 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 572.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 13 AWYKALQEQIPDFIPRPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQKTLVVSTANVALQDQI 92
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 93 YSKDLPLLRKIIP-DLRFTAAFGRGRYVCPRNLTALASTEPTQQdllafldddltpnnqaEQKLCATLKTDLDSYRWDGL 171
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLD----------------DEELLLARILAWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 172 RDHTDKPVDDALWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAMES-EAVLPEpkNLLLVLDEG 250
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 251 HHLPDVARDALemSAEMTAPWYRLQLDLFSKLVAtcmeqfRPKTTPPLANPERLSGHCEELYELIaslnailnlympaGQ 330
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 331 EAEHRFPMGELPQEVMDICQRLAKLTEMLRGLAELFLNDLGEKTgshDVVRLHRVLLQMNRALGMFesqsklwrlasLAQ 410
Cdd:COG1199 280 EEELRLALGELPDEPEELLEALDALRDALEALAEALEEELERLA---ELDALLERLEELLFALARF-----------LRI 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 411 SSGAPVTKWVTRDMRdgqtHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFSRLQEMSGLKEKAgdRFVALDS 490
Cdd:COG1199 346 AEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLPS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 491 PFNHVEQGKIVIPQMHYEPliDNEEQHIAEMAAYFREQVESKKHlGMLVLFASGRAMQRFLEHVPD-LRLLLLVQGDKPR 569
Cdd:COG1199 420 PFDYENQALLYVPRDLPRP--SDRDGYLEAIAEAIAELLEASGG-NTLVLFTSYRALEQVAELLRErLDIPVLVQGDGSR 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 570 YRLVELHRKrvegGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFN 649
Cdd:COG1199 497 EALLERFRE----GGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIK 572
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 695765691 650 LIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALPVFPIEQPAV 697
Cdd:COG1199 573 LKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEE 620
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
527-690 |
1.41e-46 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 162.73 E-value: 1.41e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 527 EQVESKKHLGMLVLFASGRAMQRFLE----HVPDLRLLLLVQ-GDKPRYRLVELHRKRVEGgerSVLVGLQ--SFAEGLD 599
Cdd:pfam13307 1 LRLLKVIPGGVLVFFPSYSYLEKVAErlkeSGLEKGIEIFVQpGEGSREKLLEEFKKKGKG---AVLFGVCggSFSEGID 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 600 LKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNY 679
Cdd:pfam13307 78 FPGDLLRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRY 157
|
170
....*....|.
gi 695765691 680 GKRLLNALPVF 690
Cdd:pfam13307 158 GKLLPKWLPPG 168
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
28-688 |
7.35e-44 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 169.60 E-value: 7.35e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 28 RPPQRQMIADVAKTLAGEEgrHLAIEAPTGVGKTLSYLIPGIAIAReQQKTLVVSTANVALQDQIYSKDLPLLRKIIP-D 106
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAI-TEKPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 107 LRFTAAFGRGRYVCPRNLTALAStEPTQQDLLAFLDDdltpnnQAEQKLCATLKTDLDSYRWDGLRDHtdkpvddaLWSR 186
Cdd:TIGR01407 324 INAALIKGKSNYLSLGKFSQILK-DNTDNYEFNIFKM------QVLVWLTETETGDLDELNLKGGNKM--------FFAQ 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 187 LSTDKAscLNRNCHYYRECPFFVARREIQEAEVVVANHA-LVMAAMESEAVLPEPKnlLLVLDEGHHLPDVARDALEMSA 265
Cdd:TIGR01407 389 VRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAyLITRLVDNPELFPSFR--DLIIDEAHHLPDIAENQLQEEL 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 266 EMTAPWYrlQLDLFsklvatcmeqfrpkttpplanperLSGHCEELyeliasLNAILNLYmpAGQEAEHRFPMgelpqEV 345
Cdd:TIGR01407 465 DYADIKY--QIDLI------------------------GKGENEQL------LKRIQQLE--KQEILEKLFDF-----ET 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 346 MDICQRLAKLTEMLRGLAELFlNDLGektgshdvvrlHRVLLQMNRALGMFESQSKlwrlaSLAQSSGAPVTKWVTRDMR 425
Cdd:TIGR01407 506 KDILKDLQAILDKLNKLLQIF-SELS-----------HKTVDQLRKFDLALKDDFK-----NIEQSLKEGHTSWISIENL 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 426 DGQTHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFSRLQEMSGLKEKagdRFVALD-SPFNHVEQGKIVIPQ 504
Cdd:TIGR01407 569 QQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEpTPLNYAENQRVLIPT 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 505 MhyEPLIDN--EEQHIAEMAAYFRE--QVESKKhlgMLVLFASGRAMQRFLEHVPDLRLL----LLVQG-DKPRYRLVel 575
Cdd:TIGR01407 646 D--APAIQNksLEEYAQEIASYIIEitAITSPK---ILVLFTSYEMLHMVYDMLNELPEFegyeVLAQGiNGSRAKIK-- 718
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 576 hrKRVEGGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVG 655
Cdd:TIGR01407 719 --KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDYVLPMAIIRLRQALG 796
|
650 660 670
....*....|....*....|....*....|...
gi 695765691 656 RLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALP 688
Cdd:TIGR01407 797 RLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
545-676 |
2.47e-29 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 113.53 E-value: 2.47e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 545 RAMQRFLEHVPD-----LRLLLLVQGDKPRYRlVELHRKRVEGGER--SVLVGLQS--FAEGLDLKGELLSQVHIHKIAF 615
Cdd:smart00491 2 RYLEQVVEYWKEngileINKPVFIEGKDSGET-EELLEKYSAACEArgALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695765691 616 PPIDSPVVITEGEWLKS-LNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLT 676
Cdd:smart00491 81 PNPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
595-673 |
4.95e-05 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 44.13 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 595 AEGLDLKGELLSQVHIHKIAFPPIDSPVVItegewLKSLNRYPFEVQSLPSASFNLIQQ--------VGRLIRSHSCWGE 666
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 695765691 667 VVIYDKR 673
Cdd:cd18788 152 IVLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
2-696 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1131.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 2 ALTAALKAQIAAWYKALQEQIPDFIPRPPQRQMIADVAKTLAGEE---GRHLAIEAPTGVGKTLSYLIPGIAIAREQQKT 78
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 79 LVVSTANVALQDQIYSKDLPLLRKIIP-DLRFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDDLTPNNQAEQKLCA 157
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 158 TLKTDLDSYRWDGLRDHTDKPVDDALWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAME--SEA 235
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 236 VLPEPKNLLLVLDEGHHLPDVARDALEMSAEM--TAPWYRLQLDLFSKLVATCMeqfrpktTPPLANPERLSGHCEELYE 313
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIM-------EPPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 314 LIASLNAILNLYMPAG-QEAEHRFPMGELPQEVMDICQRLAKLTEMLRGLAELFLNDLGE--KTGSHDVVRLHRVLLQMN 390
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 391 RALGMFESQSKLWRLAS-LAQSSGAPVTKWVTRDMRDGQTHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFS 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 470 RLQEMSGLKEKAGDRFVALDSPFNHVEQGKIVIPQMHYEPliDNEEQHIAEMAAYFREQVESKKhlGMLVLFASGRAMQR 549
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEKHK--GSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 550 FLEHVP-DLRLLLLVQGDKPRYRLVELHRKRVEGGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGE 628
Cdd:PRK11747 550 VADLLPrDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 695765691 629 WLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALPVFPIEQPA 696
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
13-697 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 572.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 13 AWYKALQEQIPDFIPRPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQKTLVVSTANVALQDQI 92
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 93 YSKDLPLLRKIIP-DLRFTAAFGRGRYVCPRNLTALASTEPTQQdllafldddltpnnqaEQKLCATLKTDLDSYRWDGL 171
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLD----------------DEELLLARILAWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 172 RDHTDKPVDDALWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAMES-EAVLPEpkNLLLVLDEG 250
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 251 HHLPDVARDALemSAEMTAPWYRLQLDLFSKLVAtcmeqfRPKTTPPLANPERLSGHCEELYELIaslnailnlympaGQ 330
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 331 EAEHRFPMGELPQEVMDICQRLAKLTEMLRGLAELFLNDLGEKTgshDVVRLHRVLLQMNRALGMFesqsklwrlasLAQ 410
Cdd:COG1199 280 EEELRLALGELPDEPEELLEALDALRDALEALAEALEEELERLA---ELDALLERLEELLFALARF-----------LRI 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 411 SSGAPVTKWVTRDMRdgqtHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFSRLQEMSGLKEKAgdRFVALDS 490
Cdd:COG1199 346 AEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLPS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 491 PFNHVEQGKIVIPQMHYEPliDNEEQHIAEMAAYFREQVESKKHlGMLVLFASGRAMQRFLEHVPD-LRLLLLVQGDKPR 569
Cdd:COG1199 420 PFDYENQALLYVPRDLPRP--SDRDGYLEAIAEAIAELLEASGG-NTLVLFTSYRALEQVAELLRErLDIPVLVQGDGSR 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 570 YRLVELHRKrvegGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFN 649
Cdd:COG1199 497 EALLERFRE----GGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIK 572
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 695765691 650 LIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALPVFPIEQPAV 697
Cdd:COG1199 573 LKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEE 620
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
15-692 |
5.07e-67 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 237.93 E-value: 5.07e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 15 YKALQEQIPDFIPRPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQKTLVVSTANVALQDQIYS 94
Cdd:PRK08074 246 EEKLSLAMPKYEKREGQQEMMKEVYTAL--RDSEHALIEAGTGTGKSLAYLLPAAYFAKKKEEPVVISTYTIQLQQQLLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 95 KDLPLLRKIIPdLRFTAAF--GRGRYVCPRNLTALASTEPTQQDLLAFLDddltpnnqaeQKLCATLKTDldsyrwDGLR 172
Cdd:PRK08074 324 KDIPLLQKIFP-FPVEAALlkGRSHYLCLRKFEQALQEEDDNYDVALTKA----------QLLVWLTETE------TGDL 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 173 DHTDKPVDDAL-WSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAMESEA-VLPEPKNLllVLDEG 250
Cdd:PRK08074 387 DELNLPSGGKLlWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEpLLPSYEHI--IIDEA 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 251 HHLPDVARDALEMSA---EMTAPWYRL----QLDLFSKLvATCMEQFRPKTTPPLANPERLSGHC-EELYELIASLNAIL 322
Cdd:PRK08074 465 HHFEEAASRHLGEQFsymSFQLLLSRLgtleEDGLLSKL-AKLFKKSDQASRSSFRDLDESLKELkFEADELFQMLRSFV 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 323 NLYMPAGQEAE--HRF----PMGELPQEVMDICQRL----AKLTEMLRGLAELFLNdlGEKTGSHDVVRLHRVLLQMNRa 392
Cdd:PRK08074 544 LKRKKQEQNGRliYRYntesEKGKLWDAITELANRLcydlRDLLTLLEAQKKELQE--KMESESAFLTGEYAHLIDLLE- 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 393 lgmFESQsklwrLASLAQSSGAPVTKWVTRDMRDGQTHIWFHCVGIRVSDQLERLLW---RSVphiVVTSATLRSLNSFS 469
Cdd:PRK08074 621 ---KMAQ-----LLQLLFEEDPDYVTWIEIDAKGAINATRLYAQPVEVAERLADEFFakkKSV---ILTSATLTVNGSFD 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 470 RLQEMSGLkEKAGDRFVALDSPFNHVEQGKIVIP-QMhyePLI--DNEEQHIAEMAAYFReQVESKKHLGMLVLFASGRA 546
Cdd:PRK08074 690 YIIERLGL-EDFYPRTLQIPSPFSYEEQAKLMIPtDM---PPIkdVPIEEYIEEVAAYIA-KIAKATKGRMLVLFTSYEM 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 547 MQRFLEHVPDL----RLLLLVQG--DKPRYRLVelhrKRVEGGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDS 620
Cdd:PRK08074 765 LKKTYYNLKNEeeleGYVLLAQGvsSGSRARLT----KQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQ 840
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695765691 621 PVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALPVFPI 692
Cdd:PRK08074 841 PVMEAKSEWAKEQGENPFQELSLPQAVLRFKQGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVPV 912
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
527-690 |
1.41e-46 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 162.73 E-value: 1.41e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 527 EQVESKKHLGMLVLFASGRAMQRFLE----HVPDLRLLLLVQ-GDKPRYRLVELHRKRVEGgerSVLVGLQ--SFAEGLD 599
Cdd:pfam13307 1 LRLLKVIPGGVLVFFPSYSYLEKVAErlkeSGLEKGIEIFVQpGEGSREKLLEEFKKKGKG---AVLFGVCggSFSEGID 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 600 LKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNY 679
Cdd:pfam13307 78 FPGDLLRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRY 157
|
170
....*....|.
gi 695765691 680 GKRLLNALPVF 690
Cdd:pfam13307 158 GKLLPKWLPPG 168
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
28-688 |
7.35e-44 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 169.60 E-value: 7.35e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 28 RPPQRQMIADVAKTLAGEEgrHLAIEAPTGVGKTLSYLIPGIAIAReQQKTLVVSTANVALQDQIYSKDLPLLRKIIP-D 106
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAI-TEKPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 107 LRFTAAFGRGRYVCPRNLTALAStEPTQQDLLAFLDDdltpnnQAEQKLCATLKTDLDSYRWDGLRDHtdkpvddaLWSR 186
Cdd:TIGR01407 324 INAALIKGKSNYLSLGKFSQILK-DNTDNYEFNIFKM------QVLVWLTETETGDLDELNLKGGNKM--------FFAQ 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 187 LSTDKAscLNRNCHYYRECPFFVARREIQEAEVVVANHA-LVMAAMESEAVLPEPKnlLLVLDEGHHLPDVARDALEMSA 265
Cdd:TIGR01407 389 VRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAyLITRLVDNPELFPSFR--DLIIDEAHHLPDIAENQLQEEL 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 266 EMTAPWYrlQLDLFsklvatcmeqfrpkttpplanperLSGHCEELyeliasLNAILNLYmpAGQEAEHRFPMgelpqEV 345
Cdd:TIGR01407 465 DYADIKY--QIDLI------------------------GKGENEQL------LKRIQQLE--KQEILEKLFDF-----ET 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 346 MDICQRLAKLTEMLRGLAELFlNDLGektgshdvvrlHRVLLQMNRALGMFESQSKlwrlaSLAQSSGAPVTKWVTRDMR 425
Cdd:TIGR01407 506 KDILKDLQAILDKLNKLLQIF-SELS-----------HKTVDQLRKFDLALKDDFK-----NIEQSLKEGHTSWISIENL 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 426 DGQTHIWFHCVGIRVSDQLERLLWRSVPHIVVTSATLRSLNSFSRLQEMSGLKEKagdRFVALD-SPFNHVEQGKIVIPQ 504
Cdd:TIGR01407 569 QQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEpTPLNYAENQRVLIPT 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 505 MhyEPLIDN--EEQHIAEMAAYFRE--QVESKKhlgMLVLFASGRAMQRFLEHVPDLRLL----LLVQG-DKPRYRLVel 575
Cdd:TIGR01407 646 D--APAIQNksLEEYAQEIASYIIEitAITSPK---ILVLFTSYEMLHMVYDMLNELPEFegyeVLAQGiNGSRAKIK-- 718
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 576 hrKRVEGGERSVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVG 655
Cdd:TIGR01407 719 --KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDYVLPMAIIRLRQALG 796
|
650 660 670
....*....|....*....|....*....|...
gi 695765691 656 RLIRSHSCWGEVVIYDKRLLTKNYGKRLLNALP 688
Cdd:TIGR01407 797 RLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
545-676 |
2.47e-29 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 113.53 E-value: 2.47e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 545 RAMQRFLEHVPD-----LRLLLLVQGDKPRYRlVELHRKRVEGGER--SVLVGLQS--FAEGLDLKGELLSQVHIHKIAF 615
Cdd:smart00491 2 RYLEQVVEYWKEngileINKPVFIEGKDSGET-EELLEKYSAACEArgALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 695765691 616 PPIDSPVVITEGEWLKS-LNRYPFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLT 676
Cdd:smart00491 81 PNPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
28-687 |
1.15e-12 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 71.64 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 28 RPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPgiAIAREQQKTLVVSTANVALQDQIYSKDLPLLRKiipdl 107
Cdd:PRK07246 247 RPKQESFAKLVGEDF--HDGPASFIEAQTGIGKTYGYLLP--LLAQSDQRQIIVSVPTKILQDQIMAEEVKAIQE----- 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 108 RFTAAFG--RGryvcPRNLTALASTEPTQQDLLAFLDDdltpNNQAEQKLCATLKT---DLDS----YRW---------D 169
Cdd:PRK07246 318 VFHIDCHslKG----PQNYLKLDAFYDSLQQNDDNRLV----NRYKMQLLVWLTETetgDLDEikqkQRYaayfdqlkhD 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 170 GLRDHTDKPVDDALWSRlSTDKAsclnrnchyyrecpffvarreiQEAEVVVANHALVMAAMESEAVLPepKNLLLVLDE 249
Cdd:PRK07246 390 GNLSQSSLFYDYDFWKR-SYEKA----------------------KTARLLITNHAYFLTRVQDDKDFA--RNKVLVFDE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 250 GHHLpdvardalemsaemtapwyRLQLDLFSKlvatcmeqfrpkttpplanperlsgHCEELYELIASLNAILNlympag 329
Cdd:PRK07246 445 AQKL-------------------MLQLEQLSR-------------------------HQLNITSFLQTIQKALS------ 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 330 qeaehrfpmGELPQevmdICQRLAK-LTEMLRGLAELFLNDLGEKTGSHDVVRLHrvllQMNRALGMFESQSkLWRLASL 408
Cdd:PRK07246 475 ---------GPLPL----LQKRLLEsISFELLQLSEQFYQGKERQLIHDSLSRLH----QYFSELEVAGFQE-LQAFFAT 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 409 AQSSgapvtKWVTRDmrdgqtHIWFHCVGIRVSDQLERLLWRS-VPHIVVT---SATLR--------SLNSFSRLQEMSG 476
Cdd:PRK07246 537 AEGD-----YWLESE------KQSEKRVTYLNSASKAFTHFSQlLPETCKTyfvSATLQisprvslaDLLGFEEYLFHKI 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 477 LKEKAGDRFVALDSPFnhveqgkivipqmhyePLID--NEEQHIAEMAayfrEQVESKKHLG--MLVLFASGRAMQRFLE 552
Cdd:PRK07246 606 EKDKKQDQLVVVDQDM----------------PLVTetSDEVYAEEIA----KRLEELKQLQqpILVLFNSKKHLLAVSD 665
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 553 HVPDLRLLLLVQG-DKPRYRLvelhRKRVEGGERSVLVGLQSFAEGLDLkgellsqVH----IHKIAFPPIDSPvvitEG 627
Cdd:PRK07246 666 LLDQWQVSHLAQEkNGTAYNI----KKRFDRGEQQILLGLGSFWEGVDF-------VQadrmIEVITRLPFDNP----ED 730
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 695765691 628 EWLKSLNRY-------PFEVQSLPSASFNLIQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRLLNAL 687
Cdd:PRK07246 731 PFVKKMNQYllqegknPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDRRILTKSYGKQILASL 797
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
25-290 |
1.53e-09 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 59.70 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 25 FIPRPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSyLIPGI---AIAREQQKTLVVSTANVALQDQIySKDLPLLR 101
Cdd:smart00488 7 YEPYPIQYEFMEELKRVL--DRGKIGILESPTGTGKTLS-LLCLTltwLRSFPERIQKIKLIYLSRTVSEI-EKRLEELR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 102 KII--------PDLRFTAAFGR--GRYVCPRNLTALAST------EPTQQDLLAFLDDDLTPNNQAEQKLCATLKTDLDS 165
Cdd:smart00488 83 KLMqkveyesdEESEKQAQLLHelGREKPKVLGLSLTSRknlclnPEVRTLKQNGLVVDEVCRSLTASKARKYRYENPKV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 166 YRwDGLRDHTDK--PVDDALWSRLSTDKASCLNRNChyyRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPEPKNL 243
Cdd:smart00488 163 ER-CPFYENTEFllVRDLLPAEVYDIEDLLELGKRL---GGCPYFASRKAIEFANVVVLPYQYLLDPKIRQALSIELKDS 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 695765691 244 LLVLDEGHHLPDVARDALemSAEMTapwyRLQLDLFSKLVATCMEQF 290
Cdd:smart00488 239 IVIFDEAHNLDNVCISAL--SSELS----RRSLERAHKNIKKYFERI 279
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
28-683 |
9.10e-08 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 55.49 E-value: 9.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 28 RPPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQKTLVVstanvalqdqIY-SKDLPLLRKIIPD 106
Cdd:TIGR00604 12 YPEQRSYMRDLKRSL--DRGDEAILEMPSGTGKTISLLSLILAYQQEKPEVRKI----------IYaSRTHSQLEQATEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 107 LRFTAAFGRGRYVCPRNLTALASTEptqqdllafldddltpnnqaEQKLCAtlktdldSYRWDGLRdhTDKPVDDAL--- 183
Cdd:TIGR00604 80 LRKLMSYRTPRIGEESPVSGLSLAS--------------------RKNLCL-------HPEVSKER--QGKVVNGKCikl 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 184 ---WSRLSTDKASClNRNCHYYRE------------------------------CPFFVARREIQEAEVVVANHALVMAA 230
Cdd:TIGR00604 131 tvsKIKEQRTEKPN-VESCEFYENfdelrevedlllseimdiedlveygellglCPYFATRKMLPFANIVLLPYQYLLDP 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 231 MESEAVLPEPKNLLLVLDEGHHLPDVARDALemSAEMTapwyRLQLDLFSKLVATCMEQFRpkttpplanpERLSGHCEE 310
Cdd:TIGR00604 210 KIRSAVSIELKDSIVIFDEAHNLDNVCISSL--SSNLS----VRSLKRCSKEIAEYFEKIE----------ERKEVDARK 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 311 LYELIASLnaILNLY-MPAGQEAEHRFPMGELPQEVmdicqrlakLTEMLRGL---AELF---LNDLGEKtgSHDVVRLH 383
Cdd:TIGR00604 274 LLDELQKL--VEGLKqEDLLTDEDIFLANPVLPKEV---------LPEAVPGNiriAEIFlhkLSRYLEY--LKDALKVL 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 384 RVLLQMNRALGMFESQSKLW---------RLASL---------AQSSGAPVT---KWVTRDMRDGQTHI----------- 431
Cdd:TIGR00604 341 GVVSELPDAFLEHLKEKTFIdrplrfcseRLSNLlreleithpEDFSALVLLftfATLVLTYTNGFLEGiepyenktvpn 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 432 -WFHCVGIRVSDQLERLL--WRSVphiVVTSATLRSLNSFSRLqemsglkekAGDRFVALDSPfNH-----------VEQ 497
Cdd:TIGR00604 421 pILKFMCLDPSIALKPLFerVRSV---ILASGTLSPLDAFPRN---------LGFNPVSQDSP-THilkrenlltliVTR 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 498 GKIVIP-QMHYEplIDNEEQHIAEMAAYFreqVESKKHL--GMLVLFASGRAMQRF---------LEHVPDLRLLLLVQG 565
Cdd:TIGR00604 488 GSDQVPlSSTFE--IRNDPSLVRNLGELL---VEFSKIIpdGIVVFFPSYSYLENIvstwkemgiLENIEKKKLIFVETK 562
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 566 DKPRYRLVELHRKR-VEGGERSVLVGLQ--SFAEGLDLKGELLSQVHIHKIAFPPIDSPVVITEGEWLKSL-----NRYP 637
Cdd:TIGR00604 563 DAQETSDALERYKQaVSEGRGAVLLSVAggKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLEFLRDQypireNQDF 642
|
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 695765691 638 FEVQSLPSASfnliQQVGRLIRSHSCWGEVVIYDKRLLTKNYGKRL 683
Cdd:TIGR00604 643 YEFDAMRAVN----QAIGRVIRHKDDYGSIVLLDKRYARSNKRKKL 684
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
25-129 |
9.60e-06 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 47.10 E-value: 9.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 25 FIPRPPQRQMIADVAktlagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQ--KTLVVStANVALQDQIYSKdlplLRK 102
Cdd:smart00487 7 EPLRPYQKEAIEALL-----SGLRDVILAAPTGSGKTLAALLPALEALKRGKggRVLVLV-PTRELAEQWAEE----LKK 76
|
90 100
....*....|....*....|....*..
gi 695765691 103 IIPDLRFTAAFGRGRYVCPRNLTALAS 129
Cdd:smart00487 77 LGPSLGLKVVGLYGGDSKREQLRKLES 103
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
595-673 |
4.95e-05 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 44.13 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 595 AEGLDLKGELLSQVHIHKIAFPPIDSPVVItegewLKSLNRYPFEVQSLPSASFNLIQQ--------VGRLIRSHSCWGE 666
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 695765691 667 VVIYDKR 673
Cdd:cd18788 152 IVLLDKR 158
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
28-114 |
6.72e-05 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 43.77 E-value: 6.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 28 RPPQRQMIADVaktlagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQ---KTLVVS-TanVALQDQIYSKdlplLRKI 103
Cdd:pfam00270 1 TPIQAEAIPAI------LEGRDVLVQAPTGSGKTLAFLLPALEALDKLDngpQALVLApT--RELAEQIYEE----LKKL 68
|
90
....*....|...
gi 695765691 104 I--PDLRFTAAFG 114
Cdd:pfam00270 69 GkgLGLKVASLLG 81
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
47-122 |
6.13e-04 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 40.85 E-value: 6.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695765691 47 GRHLAIEAPTGVGKTLSYLIPGIAIAREQQKTLVVSTANVALQDQIYSKDLPLLRKIIPdlrfTAAFGRGRYVCPR 122
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLAALLLLLKKGKKVLVLVPTKALALQTAERLRELFGPGIR----VAVLVGGSSAEER 72
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
27-95 |
7.49e-04 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 40.37 E-value: 7.49e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 27 PRPPQRQMIAdvaKTLAGEEGRHLAIEAPTGVGKTLSYLipGIAIAREQQKTL-VVSTanVALQDQIYSK 95
Cdd:cd17926 1 LRPYQEEALE---AWLAHKNNRRGILVLPTGSGKTLTAL--ALIAYLKELRTLiVVPT--DALLDQWKER 63
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
11-95 |
9.62e-04 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 42.32 E-value: 9.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 11 IAAWYKALQEQIPDFIPRPPQRQMIADVAKTLAGEEGRHLaIEAPTGVGKTLSylipGIAIARE---QQKTLVVSTaNVA 87
Cdd:COG1061 65 AEALEAGDEASGTSFELRPYQQEALEALLAALERGGGRGL-VVAPTGTGKTVL----ALALAAEllrGKRVLVLVP-RRE 138
|
....*...
gi 695765691 88 LQDQIYSK 95
Cdd:COG1061 139 LLEQWAEE 146
|
|
| DEXHc_Hrq1-like |
cd17923 |
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a ... |
43-115 |
1.86e-03 |
|
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350681 [Multi-domain] Cd Length: 182 Bit Score: 39.88 E-value: 1.86e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695765691 43 AGEEGRHLAIEAPTGVGKTLSYLIPGI-AIAREQQ-KTLVVSTANvAL-QDQIYSkdlplLRKIIPDLRFTAAFGR 115
Cdd:cd17923 11 AARAGRSVVVTTGTASGKSLCYQLPILeALLRDPGsRALYLYPTK-ALaQDQLRS-----LRELLEQLGLGIRVAT 80
|
|
| Lhr |
COG1201 |
Lhr-like helicase [Replication, recombination and repair]; |
27-63 |
1.96e-03 |
|
Lhr-like helicase [Replication, recombination and repair];
Pssm-ID: 440814 [Multi-domain] Cd Length: 850 Bit Score: 41.63 E-value: 1.96e-03
10 20 30
....*....|....*....|....*....|....*..
gi 695765691 27 PRPPQRQMIADVAktlageEGRHLAIEAPTGVGKTLS 63
Cdd:COG1201 25 PTPPQREAWPAIA------AGESTLLIAPTGSGKTLA 55
|
|
| DEADc_MRH4 |
cd17965 |
DEAD-box helicase domain of ATP-dependent RNA helicase MRH4; Mitochondrial RNA helicase 4 ... |
5-104 |
3.55e-03 |
|
DEAD-box helicase domain of ATP-dependent RNA helicase MRH4; Mitochondrial RNA helicase 4 (MRH4) plays an essential role during the late stages of mitochondrial ribosome or mitoribosome assembly by promoting remodeling of the 21S rRNA-protein interactions. MRH4 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350723 [Multi-domain] Cd Length: 251 Bit Score: 39.67 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 5 AALKAQIAAWYKALQEQIpdfIPRPPQRQMIADVAKTLAG--------EEGRH--LAIEAPTGVGKTLSYLIPGI-AIAR 73
Cdd:cd17965 12 EAIIKEILKGSNKTDEEI---KPSPIQTLAIKKLLKTLMRkvtkqtsnEEPKLevFLLAAETGSGKTLAYLAPLLdYLKR 88
|
90 100 110
....*....|....*....|....*....|.
gi 695765691 74 EQQKTLVVSTANVALQdqiysKDLPLLRKII 104
Cdd:cd17965 89 QEQEPFEEAEEEYESA-----KDTGRPRSVI 114
|
|
| DEADc_DDX51 |
cd17956 |
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by ... |
15-89 |
3.69e-03 |
|
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by regulating multiple signalling pathways. Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA.It is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350714 [Multi-domain] Cd Length: 231 Bit Score: 39.54 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 15 YKALQEQ-IPDFIPrpPQRQMIADVAKTLAGEEGRH---LAIEAPTGVGKTLSYLIPGIAIAREQQKT-----LVVSTAN 85
Cdd:cd17956 2 LKNLQNNgITSAFP--VQAAVIPWLLPSSKSTPPYRpgdLCVSAPTGSGKTLAYVLPIVQALSKRVVPrlralIVVPTKE 79
|
....
gi 695765691 86 VALQ 89
Cdd:cd17956 80 LVQQ 83
|
|
| Cas3 |
COG1203 |
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; ... |
6-77 |
4.33e-03 |
|
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 440816 [Multi-domain] Cd Length: 535 Bit Score: 40.45 E-value: 4.33e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 695765691 6 ALKAQIAAWYKALQEQIPDFI-PRPPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREQQK 77
Cdd:COG1203 105 ALDHLLAERLERLLPKKSKPRtPINPLQNEALELALEAAEEEPGLFILTAPTGGGKTEAALLFALRLAAKHGG 177
|
|
| DEADc_DDX52 |
cd17957 |
DEAD-box helicase domain of DEAD box protein 52; DDX52 (also called ROK1 and HUSSY19) is ... |
26-93 |
4.53e-03 |
|
DEAD-box helicase domain of DEAD box protein 52; DDX52 (also called ROK1 and HUSSY19) is ubiquitously expressed in testis, endometrium, and other tissues in humans. DDX52 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350715 [Multi-domain] Cd Length: 198 Bit Score: 39.11 E-value: 4.53e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 695765691 26 IPRPPQRQMIAdvaKTLAGEEgrHLAIeAPTGVGKTLSYLIPGIAIAREQQKT-----LVVSTANvALQDQIY 93
Cdd:cd17957 12 EPTPIQMQAIP---ILLHGRD--LLAC-APTGSGKTLAFLIPILQKLGKPRKKkglraLILAPTR-ELASQIY 77
|
|
| DEADc |
cd00268 |
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family ... |
46-77 |
4.53e-03 |
|
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350669 [Multi-domain] Cd Length: 196 Bit Score: 38.96 E-value: 4.53e-03
10 20 30
....*....|....*....|....*....|..
gi 695765691 46 EGRHLAIEAPTGVGKTLSYLIPGIAIAREQQK 77
Cdd:cd00268 26 SGRDVIGQAQTGSGKTLAFLLPILEKLLPEPK 57
|
|
| DEXHc_RecG |
cd17918 |
DEXH/Q-box helicase domain of DEAD-like helicase RecG family proteins; The DEAD-like helicase ... |
9-108 |
6.68e-03 |
|
DEXH/Q-box helicase domain of DEAD-like helicase RecG family proteins; The DEAD-like helicase RecG family is part of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350676 [Multi-domain] Cd Length: 180 Bit Score: 38.17 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695765691 9 AQIAAWYKALQeqipdFIPRPPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPgIAIAREQQKTLVVSTANVAL 88
Cdd:cd17918 3 ALIQELCKSLP-----FSLTKDQAQAIKDIEKDLHSPEPMDRLLSGDVGSGKTLVALGA-ALLAYKNGKQVAILVPTEIL 76
|
90 100
....*....|....*....|
gi 695765691 89 QDQIYSKdlplLRKIIPDLR 108
Cdd:cd17918 77 AHQHYEE----ARKFLPFIN 92
|
|
| |
