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Conserved domains on  [gi|695733882|ref|WP_032660362|]
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MULTISPECIES: DNA-binding transcriptional repressor [Enterobacter]

Protein Classification

glucitol operon DNA-binding transcriptional repressor SrlR( domain architecture ID 11484720)

glucitol operon DNA-binding transcriptional repressor SrlR

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
srlR PRK10434
DNA-binding transcriptional repressor;
1-256 0e+00

DNA-binding transcriptional repressor;


:

Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 531.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNKDEADPPIDHKTLINTHQKAL 80
Cdd:PRK10434   1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  81 IAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQTILMPGGTFRKKSASFHGQLAENA 160
Cdd:PRK10434  81 IAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 161 FEHFSFDKLFMGTDGIDLNAGVTTFNEVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFKK 240
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGVTTFNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQ 240

                        250
                 ....*....|....*.
gi 695733882 241 ALEEKGIDVIVTGERD 256
Cdd:PRK10434 241 ALEEKGIEVIITGESN 256
 
Name Accession Description Interval E-value
srlR PRK10434
DNA-binding transcriptional repressor;
1-256 0e+00

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 531.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNKDEADPPIDHKTLINTHQKAL 80
Cdd:PRK10434   1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  81 IAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQTILMPGGTFRKKSASFHGQLAENA 160
Cdd:PRK10434  81 IAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 161 FEHFSFDKLFMGTDGIDLNAGVTTFNEVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFKK 240
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGVTTFNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQ 240

                        250
                 ....*....|....*.
gi 695733882 241 ALEEKGIDVIVTGERD 256
Cdd:PRK10434 241 ALEEKGIEVIITGESN 256
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-251 2.73e-107

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 310.53  E-value: 2.73e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLN-KDEADPPIDHKTLINTHQKA 79
Cdd:COG1349    1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVsSAAAEPPFAERETLNAEEKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  80 LIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEfDSEQTILMPGGTFRKKSASFHGQLAEN 159
Cdd:COG1349   81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAE-RPNIEVILLGGELRPSSGSLVGPLAEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 160 AFEHFSFDKLFMGTDGIDLNAGVTTFN-EVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAF 238
Cdd:COG1349  160 ALRRFRADKAFLGASGIDAEGGLTTFDeEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPEL 239

                        250
                 ....*....|...
gi 695733882 239 KKALEEKGIDVIV 251
Cdd:COG1349  240 LEALEEAGVEVIV 252
AgaR NF040755
transcriptional repressor AgaR;
5-251 3.72e-77

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 234.09  E-value: 3.72e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   5 QRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNK---DEADPPIDHKTLINTHQKALI 81
Cdd:NF040755   6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDgfiPGAEPSVEDKSRLNTAVKRLI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  82 AEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQtILMPGGTFRKKSASFHGQLAENAF 161
Cdd:NF040755  86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVE-VLMTGGHLRRQSLSFYGDQAEQSL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 162 EHFSFDKLFMGTDGIDLNAGVTTFNE-VFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFKK 240
Cdd:NF040755 165 QNYHFDKLFLGVDGFDLERGITTHNEdEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPEEYLQ 244

                        250
                 ....*....|.
gi 695733882 241 ALEEKGIDVIV 251
Cdd:NF040755 245 GLRKLGVEVIL 255
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 73-232 5.46e-66

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 201.97  E-value: 5.46e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   73 INTHQKALIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDsEQTILMPGGTFRKKSASF 152
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKP-DIEVILLGGEVRPKTGAF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  153 HGQLAENAFEHFSFDKLFMGTDGIDLNAGVTTFNE-VFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITD 231
Cdd:pfam00455  80 VGPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEeEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159


                  .
gi 695733882  232 A 232
Cdd:pfam00455 160 K 160
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 4.75e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 69.94  E-value: 4.75e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 695733882     6 RQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVL 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
 
Name Accession Description Interval E-value
srlR PRK10434
DNA-binding transcriptional repressor;
1-256 0e+00

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 531.19  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNKDEADPPIDHKTLINTHQKAL 80
Cdd:PRK10434   1 MKPRQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  81 IAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQTILMPGGTFRKKSASFHGQLAENA 160
Cdd:PRK10434  81 IAEAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 161 FEHFSFDKLFMGTDGIDLNAGVTTFNEVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFKK 240
Cdd:PRK10434 161 FEHFTFDKLFIGTDGIDLNAGVTTFNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQ 240

                        250
                 ....*....|....*.
gi 695733882 241 ALEEKGIDVIVTGERD 256
Cdd:PRK10434 241 ALEEKGIEVIITGESN 256
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 1-251 2.73e-107

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 310.53  E-value: 2.73e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLN-KDEADPPIDHKTLINTHQKA 79
Cdd:COG1349    1 MLAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVsSAAAEPPFAERETLNAEEKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  80 LIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEfDSEQTILMPGGTFRKKSASFHGQLAEN 159
Cdd:COG1349   81 AIARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAE-RPNIEVILLGGELRPSSGSLVGPLAEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 160 AFEHFSFDKLFMGTDGIDLNAGVTTFN-EVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAF 238
Cdd:COG1349  160 ALRRFRADKAFLGASGIDAEGGLTTFDeEEAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPEL 239

                        250
                 ....*....|...
gi 695733882 239 KKALEEKGIDVIV 251
Cdd:COG1349  240 LEALEEAGVEVIV 252
AgaR NF040755
transcriptional repressor AgaR;
5-251 3.72e-77

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 234.09  E-value: 3.72e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   5 QRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNK---DEADPPIDHKTLINTHQKALI 81
Cdd:NF040755   6 ERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALINDgfiPGAEPSVEDKSRLNTAVKRLI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  82 AEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQtILMPGGTFRKKSASFHGQLAENAF 161
Cdd:NF040755  86 AAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEGVE-VLMTGGHLRRQSLSFYGDQAEQSL 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 162 EHFSFDKLFMGTDGIDLNAGVTTFNE-VFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFKK 240
Cdd:NF040755 165 QNYHFDKLFLGVDGFDLERGITTHNEdEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPEEYLQ 244

                        250
                 ....*....|.
gi 695733882 241 ALEEKGIDVIV 251
Cdd:NF040755 245 GLRKLGVEVIL 255
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 73-232 5.46e-66

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 201.97  E-value: 5.46e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   73 INTHQKALIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDsEQTILMPGGTFRKKSASF 152
Cdd:pfam00455   1 ENAEEKRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKP-DIEVILLGGEVRPKTGAF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  153 HGQLAENAFEHFSFDKLFMGTDGIDLNAGVTTFNE-VFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITD 231
Cdd:pfam00455  80 VGPLAEEFLRQFNVDKAFIGANGIDLEGGLTTSDEeEAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITD 159


                  .
gi 695733882  232 A 232
Cdd:pfam00455 160 K 160
PRK09802 PRK09802
DeoR family transcriptional regulator;
4-254 5.38e-63

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 198.54  E-value: 5.38e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   4 RQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVL---NKDEADPPIDHKTLINTHQKAL 80
Cdd:PRK09802  16 SERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALIcdsTTPSVEPSVEDKSALNTAMKRS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  81 IAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSeQTILMPGGTFRKKSASFHGQLAENA 160
Cdd:PRK09802  96 VAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEG-VELLMTGGHLRRQSQSFYGDQAEQS 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 161 FEHFSFDKLFMGTDGIDLNAGVTTFNEVFS-VSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAFK 239
Cdd:PRK09802 175 LQNYHFDMLFLGVDAIDLERGVSTHNEDEArLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSL 254

                        250
                 ....*....|....*
gi 695733882 240 KALEEKGIDVIVTGE 254
Cdd:PRK09802 255 EGLRKAGVEVILVGE 269
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
1-251 4.10e-28

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 107.78  E-value: 4.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAV--IRTYGGVVLNKDEADPPIDHKTLINTHQK 78
Cdd:PRK13509   1 MTEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLkkVRNGAEAITQQRPRWTPMNIHQAQNHDEK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  79 ALIAEAAVKFIHDGDSIILDAGSTVLqmipLLSRF---NNITVMTNSLHIVNALSEFDSEQTILMpGGTFRKKSASFhgq 155
Cdd:PRK13509  81 VRIAKAASQLCNPGESVVINCGSTAF----LLGRElcgKPVQIITNYLPLANYLIDQEHDSVIIM-GGQYNKSQSIT--- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 156 LAENAFEHFSFDKLFMGTDGIDLNA-GVTTFNEVFSVSKA-MCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAG 233
Cdd:PRK13509 153 LSPQGSENSLYAGHWMFTSGKGLTAdGLYKTDMLTAMAEQkMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKN 232

                        250
                 ....*....|....*...
gi 695733882 234 IDPAFKKALEEKGIDVIV 251
Cdd:PRK13509 233 ADPEVLQQLEAQGVSILL 250
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
1-247 2.09e-27

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 105.71  E-value: 2.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNKDEADPPIDHKTLINTHQKAL 80
Cdd:PRK10906   1 MKQTQRHDAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGAALPSSSVNTPWHDRKATQTEEKER 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  81 IAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQTILmPGGTFRKKSASFHGQLAENA 160
Cdd:PRK10906  81 IARKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDFRIIL-AGGELRSRDGGIIGEATLDF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 161 FEHFSFDKLFMGTDGIDLNAGVTTFN--EVfSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDAGIDPAF 238
Cdd:PRK10906 160 ISQFRLDFGILGISGIDSDGSLLEFDyhEV-RTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDQLPPASV 238


                 ....*....
gi 695733882 239 KKALEEKGI 247
Cdd:PRK10906 239 MQVIEDHHV 247
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 1-250 5.06e-17

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 77.81  E-value: 5.06e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   1 MKPR--QRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVllENSGAVIRTYGGVVLnkdeaDPPIDHKTLINTHQ- 77
Cdd:PRK10681   1 METRrdERIGQLLQALKRSDKLHLKDAAALLGVSEMTIRRDLN--AHSAPVVLLGGYIVL-----EPRSASHYLLSDQKs 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  78 -----KALIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMTNSLHIVNALSEFDSEQTILMpGGTFRKKSASF 152
Cdd:PRK10681  74 rlveeKRRAAQLAATLVEPNQTLFFDCGTTTPWIIEAIDNELPFTAVCYSLNTFLALQEKPHCRAILC-GGEFHASNAIF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882 153 HGQLAENAFEHFSFDKLFMGTDGIDLNAGVTTFN--EVFSVSKAMcNAAREVILMADSSKFGRKSPNIVCSLESVDKLIT 230
Cdd:PRK10681 153 KPLDFQQTLDNICPDIAFYSAAGVHVSKGATCFNleELPVKHWAM-AMAQKHVLVVDHSKFGKVRPARMGDLTRFDTVVS 231

                        250       260
                 ....*....|....*....|
gi 695733882 231 DAGIDPAFKKALEEKGIDVI 250
Cdd:PRK10681 232 DRCPDDEFVKYAQAQRIKLM 251
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
6-60 6.45e-17

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 72.68  E-value: 6.45e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 695733882    6 RQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNK 60
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSNS 55
PRK10411 PRK10411
L-fucose operon activator;
6-232 2.45e-16

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 75.61  E-value: 2.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882   6 RQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVL----NKDEADPpidHKTLINTH--QKA 79
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYihrqNQDSGDP---FHIRLKSHyaHKA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695733882  80 LIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFnNITVMTNSLHIVNALSEFDsEQTILMPGGTFRKKSASFHGQLAEN 159
Cdd:PRK10411  82 DIAREALAWIEEGMVIALDASSTCWYLARQLPDI-NIQVFTNSHPICQELGKRE-RIQLISSGGTLERKYGCYVNPSLIS 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 695733882 160 AFEHFSFDKLFMGTDGIDlNAGV----TTFNEVFsvSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDA 232
Cdd:PRK10411 160 QLKSLEIDLFIFSCEGID-SSGAlwdsNAINADY--KSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDE 233
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
6-58 4.75e-16

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 69.94  E-value: 4.75e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 695733882     6 RQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVL 58
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAVS 53
YobV COG2378
Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains ...
 1-67 1.06e-06

Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains [Transcription];


Pssm-ID: 441945 [Multi-domain]  Cd Length: 314  Bit Score: 48.92  E-value: 1.06e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 695733882   1 MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRT----YGGVVLNKDEADPPI 67
Cdd:COG2378    1 MSRLERLLALLQLLQSRRGVTAAELAERLEVSERTIYRDIDALRELGVPIEAergrGGGYRLRDGYRLPPL 71
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
6-53 1.66e-04

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 41.45  E-value: 1.66e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 695733882   6 RQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTY 53
Cdd:COG2345   14 TRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERET 61
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 9-50 9.12e-03

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 33.56  E-value: 9.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 695733882    9 AILEHL-QKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVI 50
Cdd:pfam08279   2 QILQLLlEARGPISGQELAEKLGVSRRTIRRDIKILEELGVPI 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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