|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
1-972 |
1.35e-91 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 314.82 E-value: 1.35e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 1 MKILTIRLKNLASIEGTFEIDFQAEPLRSAGIFAISGPTGAGKSTILDALCLALYDKTPRFSASVESlymsdigesrvnQ 80
Cdd:PRK10246 1 MKILSLRLKNLNSLKGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQS------------Q 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 81 ADvknILRRGTGEGFAEVDFlGASGHCYRSRWSVRRTGSRANGALRSQTIQVTDLTANQELQGTRKELLAQLVTLVGLTY 160
Cdd:PRK10246 69 ND---LMTRDTAECLAEVEF-EVKGEAYRAFWSQNRARNQPDGNLQAPRVELARCADGKILADKVKDKLELTATLTGLDY 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 161 EQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLKSNATLIELLSEEEITLLrte 240
Cdd:PRK10246 145 GRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSL--- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 241 KESLTNLREQGSKALIDLNAQLSVLHTL----KLQQEQRDKKVQDMRLDEEKSK---------------KLREEYTRQSD 301
Cdd:PRK10246 222 TASLQVLTDEEKQLLTAQQQQQQSLNWLtrldELQQEASRRQQALQQALAAEEKaqpqlaalslaqparQLRPHWERIQE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 302 slirfrgQCEAVQPDLSRARELDVQIQSLVSQSKqveEILQGAEKAANAQANKLQSVQGALHTscHSLKNLTGEiELPVT 381
Cdd:PRK10246 302 -------QSAALAHTRQQIEEVNTRLQSTMALRA---RIRHHAAKQSAELQAQQQSLNTWLAE--HDRFRQWNN-ELAGW 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 382 EETGLFLESVRNRLKEQEDQLAILQEKNEArvnrLNAFGIEAVTDEQARWMQEQTRLQNARQQMLEWRKAGTEAERLKAQ 461
Cdd:PRK10246 369 RAQFSQQTSDREQLRQWQQQLTHAEQKLNA----LPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQ 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 462 QEE--MGHKQEQMRKEITLLTTRLS--EKEAELKVLQRLFE-NARIamgKDVRTLRQNLRENEPCPVCGGTDHP----YR 532
Cdd:PRK10246 445 LQVaiQNVTQEQTQRNAALNEMRQRykEKTQQLADVKTICEqEARI---KDLEAQRAQLQAGQPCPLCGSTSHPaveaYQ 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 533 NEEQVVHSLYQN-IEQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAEQKRPSSEEEQNP------- 604
Cdd:PRK10246 522 ALEPGVNQSRLDaLEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPqddiqpw 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 605 ----DYFEKQLHTVQGKLNL---LAEKMHQYHQLYKEWQQHEGQIRTVRSA----------------------------- 648
Cdd:PRK10246 602 ldaqEEHERQLRLLSQRHELqgqIAAHNQQIIQYQQQIEQRQQQLLTALAGyaltlpqedeeaswlatrqqeaqswqqrq 681
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 649 --CEALREGVARCHLLMQQVLAAKEQFEllkTAETTAREQFRVVSEQLITLR-----------QERAPL----------L 705
Cdd:PRK10246 682 neLTALQNRIQQLTPLLETLPQSDDLPH---SEETVALDNWRQVHEQCLSLHsqlqtlqqqdvLEAQRLqkaqaqfdtaL 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 706 KGKSVEDAEAAIRKKEKQlnDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIADPEHLPETIARQQATNQE 785
Cdd:PRK10246 759 QASVFDDQQAFLAALLDE--ETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQIQQELAQLAQ 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 786 TERRLSTVEARLLQQ----EQNRKKLKQLEQELTEKQETANRWGKLNKLIGSADGTKFKVIAQSYTLNLLLMHANKHLSY 861
Cdd:PRK10246 837 QLRENTTRQGEIRQQlkqdADNRQQQQALMQQIAQATQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVWLANQQLTR 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 862 LSKRYRLQ-QVPGTLALQVIDCDMCDEVRTVYSLSGGESFLISLALALGLSSLSSNNLKVESLFIDEGFGSLDADSLRTV 940
Cdd:PRK10246 917 LHGRYLLQrKASEALELEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTA 996
|
1050 1060 1070
....*....|....*....|....*....|..
gi 695336968 941 MEALEQLQMQGRKIGVISHVQEMSERIAVQVQ 972
Cdd:PRK10246 997 LDALDALNASGKTIGVISHVEAMKERIPVQIK 1028
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1-979 |
7.27e-63 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 231.78 E-value: 7.27e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 1 MKILTIRLKNLASIEGTFEIDFQAEPlrsaGIFAISGPTGAGKSTILDALCLALYDKTPRFSASVESLYMSDigesrvnq 80
Cdd:TIGR00618 1 MKPLRLTLKNFGSYKGTHTIDFTALG----PIFLICGKTGAGKTTLLDAITYALYGKLPRRSEVIRSLNSLY-------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 81 advknilRRGTGEGFAEVDFLgASGHCYRSRWSVRRTGSRANGALRSQTIQVTDLTANQELQGTRKELLAQLVTLVGLTY 160
Cdd:TIGR00618 69 -------AAPSEAAFAELEFS-LGTKIYRVHRTLRCTRSHRKTEQPEQLYLEQKKGRGRILAAKKSETEEVIHDLLKLDY 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 161 EQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLKSNATLIELLSEEEITLLRTE 240
Cdd:TIGR00618 141 KTFTRVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 241 KESLTNLREQGSKALIDLNAQLSVLHTLKLQQEQRDKKVQDMRLDEEKSKKLREEYTRQSDS--LIRFRGQCEAVQPDLS 318
Cdd:TIGR00618 221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETqeRINRARKAAPLAAHIK 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 319 RARELDVQIQSlVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLTGEIELPVTEETGLFLE-----SVRN 393
Cdd:TIGR00618 301 AVTQIEQQAQR-IHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIscqqhTLTQ 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 394 RLKEQEDQLAILQEKNEARVNRLnafgiEAVTDEQARWMQEQTRLQNARQQMLEWRKAGTEAERLKAQQEEMGHKQEQMR 473
Cdd:TIGR00618 380 HIHTLQQQKTTLTQKLQSLCKEL-----DILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 474 K----EITLLTTRLSEKEAELKVLQRLFEnaRIAMGKDVRTLRQNLRENEPCPVCGGTDHPYRNE--------------- 534
Cdd:TIGR00618 455 KlekiHLQESAQSLKEREQQLQTKEQIHL--QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARqdidnpgpltrrmqr 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 535 -EQVVHSLYQNIEQEYQTASAEYQQ---LNNRNIALKQDLLHLSELSGE----------ITVQLQAFLQEAEQKRPSSEE 600
Cdd:TIGR00618 533 gEQTYAQLETSEEDVYHQLTSERKQrasLKEQMQEIQQSFSILTQCDNRskedipnlqnITVRLQDLTEKLSEAEDMLAC 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 601 EQNPDYFEKQ-----------------------LHTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIR--------TVRSAC 649
Cdd:TIGR00618 613 EQHALLRKLQpeqdlqdvrlhlqqcsqelalklTALHALQLTLTQERVREHALSIRVLPKELLASRqlalqkmqSEKEQL 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 650 EALREGVARCHLLMQQVLAA--------KEQFELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAEAAIRKK- 720
Cdd:TIGR00618 693 TYWKEMLAQCQTLLRELETHieeydrefNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTa 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 721 EKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIADPEHLPETIARQQATNQ--ETERRLSTVEARLL 798
Cdd:TIGR00618 773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRleEKSATLGEITHQLL 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 799 QQEQNRKKLKQLEQELTEKQETANRWGKLNKLIGSADGTKFKVIAQSYTLNLLLMHANKHLSYLSKRYRLQQV---PGTL 875
Cdd:TIGR00618 853 KYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGRFHGRYADSHVnarKYQG 932
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 876 ALQVIDCDMCDEVRTVYSLSGGESFLISLALALGLSSLSSNNLK--VESLFIDEGFGSLDADSLRTVMEALEQLQMQGRK 953
Cdd:TIGR00618 933 LALLVADAYTGSVRPSATLSGGETFLASLSLALALADLLSTSGGtvLDSLFIDEGFGSLDEDSLDRAIGILDAIREGSKM 1012
|
1050 1060
....*....|....*....|....*.
gi 695336968 954 IGVISHVQEMSERIAVQVQLHRAANG 979
Cdd:TIGR00618 1013 IGIISHVPEFRERIPHRILVKKTNAG 1038
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
1-179 |
2.09e-23 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 99.27 E-value: 2.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 1 MKILTIRLKNLASIEGTFEIDFQaePLRSAGIFAISGPTGAGKSTILDALCLALYDKTPRfSASVESLYMSdigesrvnq 80
Cdd:cd03279 1 MKPLKLELKNFGPFREEQVIDFT--GLDNNGLFLICGPTGAGKSTILDAITYALYGKTPR-YGRQENLRSV--------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 81 advknilrRGTGEGFAEVDF-LGASGHCYRsrwsVRRTGsrangalrsqtiqvtdltanqelqgtrkellaqlvtlvGLT 159
Cdd:cd03279 69 --------FAPGEDTAEVSFtFQLGGKKYR----VERSR--------------------------------------GLD 98
|
170 180
....*....|....*....|
gi 695336968 160 YEQFTRTVLLAQNDFATFLK 179
Cdd:cd03279 99 YDQFTRIVLLPQGEFDRFLA 118
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
889-981 |
5.13e-22 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 95.41 E-value: 5.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 889 RTVYSLSGGESFLISLALAL--GLSSLSSNNLKVESLFIDEGFGSLDADSLRTVMEALEQLQMQGRKIGVISHVQEMSER 966
Cdd:cd03279 119 RPVSTLSGGETFLASLSLALalSEVLQNRGGARLEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEELKER 198
|
90
....*....|....*
gi 695336968 967 IAVQVQLHRAANGKS 981
Cdd:cd03279 199 IPQRLEVIKTPGGSR 213
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
2-225 |
3.98e-18 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 83.91 E-value: 3.98e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 2 KILTIRLKNLASIEGTFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYdktprfsasveslymsdiGESRVNQA 81
Cdd:COG0419 1 KLLRLRLENFRSYRDTETIDF------DDGLNLIVGPNGAGKSTILEAIRYALY------------------GKARSRSK 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 82 DVKNILRRGTGEGFAEVDFLgASGHCYRSRWsvrrtgsrangalrsqtiqvtdltanqelqgtrkellaqlvtlvgltye 161
Cdd:COG0419 57 LRSDLINVGSEEASVELEFE-HGGKRYRIER------------------------------------------------- 86
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 695336968 162 qftrtvllAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLKSNATL 225
Cdd:COG0419 87 --------RQGEFAEFLEAKPSERKEALKRLLGLEIYEELKERLKELEEALESALEELAELQKL 142
|
|
| AAA_23 |
pfam13476 |
AAA domain; |
6-221 |
4.74e-17 |
|
AAA domain;
Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 80.23 E-value: 4.74e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 6 IRLKNLASIEGtFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTPRfsasveslyMSDIGESRVNQADVkN 85
Cdd:pfam13476 1 LTIENFRSFRD-QTIDF------SKGLTLITGPNGSGKTTILDAIKLALYGKTSR---------LKRKSGGGFVKGDI-R 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 86 ILRRGTGEGFAEVDFLGASGhcyRSRWSVRRTgsrangalRSQTIQVTDLTANQELQGTRKELLAQLV-TLVGLTYEQFT 164
Cdd:pfam13476 64 IGLEGKGKAYVEITFENNDG---RYTYAIERS--------RELSKKKGKTKKKEILEILEIDELQQFIsELLKSDKIILP 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 695336968 165 RTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLKS 221
Cdd:pfam13476 133 LLVFLGQEREEEFERKEKKERLEELEKALEEKEDEKKLLEKLLQLKEKKKELEELKE 189
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1-831 |
8.73e-14 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 75.87 E-value: 8.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 1 MKILTIRLKNLASIEGTfEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTPRFSASVEslymsdigesrvnq 80
Cdd:PRK03918 1 MKIEELKIKNFRSHKSS-VVEF------DDGINLIIGQNGSGKSSILEAILVGLYWGHGSKPKGLK-------------- 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 81 advKNILRRGTGEGFAEVDFLGASGHCYRsrwsVRRTGSRANGALRSQTIQVTDLTANQELQGTRKELLAqlvtlvgltY 160
Cdd:PRK03918 60 ---KDDFTRIGGSGTEIELKFEKNGRKYR----IVRSFNRGESYLKYLDGSEVLEEGDSSVREWVERLIP---------Y 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 161 EQFTRTVLLAQNDFATFLKSRESaKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLKSnatliELLSEEEITLLRTE 240
Cdd:PRK03918 124 HVFLNAIYIRQGEIDAILESDES-REKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEK-----FIKRTENIEELIKE 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 241 KESltnlreqgskaliDLNAQLSVLHTLKLQQEQRDKKVQDMRLDEEKSKKLREEYTRQSDSLIRFRGQCEAVQPDL--- 317
Cdd:PRK03918 198 KEK-------------ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIrel 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 318 -SRARELDVQIQSLVSQSKQVEEILQGAEK--AANAQANKLQSVQGALHTSCHSLKNLTGEIE--LPVTEETGLFLESVR 392
Cdd:PRK03918 265 eERIEELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEerIKELEEKEERLEELK 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 393 NRLKEQEDQLAILQEKNEArvnrlnafgieavtdeqarwmQEQTRLQNARQQMLEWRKAGTEAERLKAQQEEMGHKQEQM 472
Cdd:PRK03918 345 KKLKELEKRLEELEERHEL---------------------YEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEI 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 473 RKEITLLTTRLSEKEAELKVLQRLFENARIAMGKdvrtlrqnlrenepCPVCGG--TDHPYRNEEQVVHSLYQNIEQEYQ 550
Cdd:PRK03918 404 EEEISKITARIGELKKEIKELKKAIEELKKAKGK--------------CPVCGRelTEEHRKELLEEYTAELKRIEKELK 469
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 551 TASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQafLQEAEQKRPSSEEEQnpdyfekqlhtvqgklnlLAEKMHQYHQ 630
Cdd:PRK03918 470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQ--LKELEEKLKKYNLEE------------------LEKKAEEYEK 529
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 631 LYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQF-ELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKS 709
Cdd:PRK03918 530 LKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaELLKELEELGFESVEELEERLKELEPFYNEYLELKD 609
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 710 VEDAEAAIRKKEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDElmlrkeqiadpehlpETIARQQATNQETERR 789
Cdd:PRK03918 610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE---------------EEYEELREEYLELSRE 674
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 695336968 790 LSTVEARLLQQEQNR----KKLKQLEQELTEKQETANRWGKLNKLI 831
Cdd:PRK03918 675 LAGLRAELEELEKRReeikKTLEKLKEELEEREKAKKELEKLEKAL 720
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
214-814 |
4.54e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.80 E-value: 4.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 214 AELNQLKSNATLIEL-LSEEEITLLRTEKESLTNLREQGSKALIDLNAQLSvlhTLKLQQEQRDKKVQDMRLDEEKSKKL 292
Cdd:COG1196 220 EELKELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELE---ELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 293 REEYTRQSDSlirfrgQCEAVQPDLSRARELDVQIQSLVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNL 372
Cdd:COG1196 297 LARLEQDIAR------LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 373 TGEIElpvteetglflESVRNRLKEQEDQLAILQEKNEARVNRLNAFG-IEAVTDEQARWMQEQTRLQNARQQMLEwrka 451
Cdd:COG1196 371 EAELA-----------EAEEELEELAEELLEALRAAAELAAQLEELEEaEEALLERLERLEEELEELEEALAELEE---- 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 452 gtEAERLKAQQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAmgkdvrtlrqnlrenepcpvcggtdhpy 531
Cdd:COG1196 436 --EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE---------------------------- 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 532 RNEEQVVHSLYQNIEQEYQ--TASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAEQKRPSSEEEQNPDYFEK 609
Cdd:COG1196 486 LAEAAARLLLLLEAEADYEgfLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 610 QLHTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQFELLKTAETTARE-QFR 688
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTlAGR 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 689 VVSEQLITLRQERAPLLKGKSVEDAEAAIRKKEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIAD 768
Cdd:COG1196 646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 695336968 769 PEHLPETIARQQATNQETERRLSTVEA-----RLLQQEQNRKKLKQLEQEL 814
Cdd:COG1196 726 LEEQLEAEREELLEELLEEEELLEEEAleelpEPPDLEELERELERLEREI 776
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
388-967 |
9.62e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 9.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 388 LESVRNRLKEQEDQLAILQEKNEARVNRLNAFGIEAVTDE-QARWMQEQTRLQNARQQMLEWRKAGTEAERLKAQQEEMG 466
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAlEAELAELPERLEELEERLEELRELEEELEELEAELAELQ 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 467 HKQEQMRKEITLLT-TRLSEKEAELKVLQRLFENARiamgKDVRTLRQNLRENEpcpvcggTDHPYRNEEQVVHSLYQNI 545
Cdd:COG4717 177 EELEELLEQLSLATeEELQDLAEELEELQQRLAELE----EELEEAQEELEELE-------EELEQLENELEAAALEERL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 546 EQEYQTASA-----EYQQLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAEQKRPSSEEEQNPDYFEKQLHTvQGKLNL 620
Cdd:COG4717 246 KEARLLLLIaaallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEE-EELEEL 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 621 LAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARchllmqqvlaakeqfellktaettareqfrvvsEQLITLRQE 700
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE---------------------------------LQLEELEQE 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 701 RAPLLKGKSVEDaEAAIRKKEKQLNDsVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLrKEQIADPEHLPETIARQQ 780
Cdd:COG4717 372 IAALLAEAGVED-EEELRAALEQAEE-YQELKEELEELEEQLEELLGELEELLEALDEEEL-EEELEELEEELEELEEEL 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 781 ATNQETERRLSTVEARLLQQEQNRKKLKQLEQELTEKQETANRWGKLNklIGSADGTKFKVIAQSYTLNLLLMHANKHLS 860
Cdd:COG4717 449 EELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALK--LALELLEEAREEYREERLPPVLERASEYFS 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 861 YLSK-RYRLQQVPGTLALQVIDCDmcDEVRTVYSLSGGESF---------LISLALALGLsslssnnlkveSLFIDEGFG 930
Cdd:COG4717 527 RLTDgRYRLIRIDEDLSLKVDTED--GRTRPVEELSRGTREqlylalrlaLAELLAGEPL-----------PLILDDAFV 593
|
570 580 590
....*....|....*....|....*....|....*..
gi 695336968 931 SLDADSLRTVMEALEQLQmQGRKIGVISHVQEMSERI 967
Cdd:COG4717 594 NFDDERLRAALELLAELA-KGRQVIYFTCHEELVELF 629
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
236-823 |
9.97e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 9.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 236 LLRTEKESLTNLREQGSKALIdlnaqlsvLHTLKLQQEQRDKKVQDMRLDEekskkLREEYTRQSDSLIRFRGQCEAVQp 315
Cdd:TIGR02168 194 ILNELERQLKSLERQAEKAER--------YKELKAELRELELALLVLRLEE-----LREELEELQEELKEAEEELEELT- 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 316 dlSRARELDVQIQSLVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLtgEIELPVTEETGLFLESVRNRL 395
Cdd:TIGR02168 260 --AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL--ERQLEELEAQLEELESKLDEL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 396 KE----QEDQLAILQEKNEARVNRLNAF----------------GIEAVTDEQARwMQEQTRLQNARQQMLEWRKAGTEA 455
Cdd:TIGR02168 336 AEelaeLEEKLEELKEELESLEAELEELeaeleelesrleeleeQLETLRSKVAQ-LELQIASLNNEIERLEARLERLED 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 456 ERLKAQQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAmgkdVRTLRQNLRENEPCPVcggtdhPYRNEE 535
Cdd:TIGR02168 415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEAEQALD------AAEREL 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 536 QVVHS---LYQNIEQEYQTASAEYQQLNNRNIALKQDLLHLSELsgeITVQ------LQAFLQEAEQKRPSSEEEQNPDY 606
Cdd:TIGR02168 485 AQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL---ISVDegyeaaIEAALGGRLQAVVVENLNAAKKA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 607 FEKQLHTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQFELLKTAETTARE- 685
Cdd:TIGR02168 562 IAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKl 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 686 --QFRVV----------------SEQLITLRQERAPLLK--GKSVEDAEAAIRKKEKQLND---SVEQVRKEGEEVQSRI 742
Cdd:TIGR02168 642 rpGYRIVtldgdlvrpggvitggSAKTNSSILERRREIEelEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKEL 721
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 743 SGMQGEIRQLNSSIDELMLRKEQIADP-EHLPETIARQQATNQETERRLSTVEARLLQQEQNRKKLKQLEQELTEKQETA 821
Cdd:TIGR02168 722 EELSRQISALRKDLARLEAEVEQLEERiAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801
|
..
gi 695336968 822 NR 823
Cdd:TIGR02168 802 RE 803
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
230-827 |
2.90e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.14 E-value: 2.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 230 SEEEITLLRTEKESLTNLREQGSKALIDLNAQLSVL------HTLKLQQEQRDKKVQDMRLDEEKSKK--LREEYTRQSD 301
Cdd:TIGR02168 265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLeqqkqiLRERLANLERQLEELEAQLEELESKLdeLAEELAELEE 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 302 SLIRFRGQCEAVQPDLSRAREldvQIQSLVSQSKQVEEILQGAEKA-------ANAQANKLQSVQGALHTSCHSLKNLTG 374
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEA---ELEELESRLEELEEQLETLRSKvaqlelqIASLNNEIERLEARLERLEDRRERLQQ 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 375 EIELPVTEETGLFLESVRNRLKEQEDQLAILQEKNEARVNRLNAfgieavtdEQARWMQEQTRLQNARQQM--LEWRKAG 452
Cdd:TIGR02168 422 EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE--------LREELEEAEQALDAAERELaqLQARLDS 493
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 453 TEAERLKAQQEEMGHKQEQM-RKEITLLTTRLSE-----KEAELKVLQRLFENARIAMGKDVRTLRQN---LRENE---- 519
Cdd:TIGR02168 494 LERLQENLEGFSEGVKALLKnQSGLSGILGVLSElisvdEGYEAAIEAALGGRLQAVVVENLNAAKKAiafLKQNElgrv 573
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 520 ---PCPVCGGTDHPYRNEEQVV-HSLYQNIEQEYQTASAEYQQLNN---RNIALKQDLLHLSELSGEITVQLQAFLQEAE 592
Cdd:TIGR02168 574 tflPLDSIKGTEIQGNDREILKnIEGFLGVAKDLVKFDPKLRKALSyllGGVLVVDDLDNALELAKKLRPGYRIVTLDGD 653
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 593 QKRP-------SSEEEQNPDYFEKQLHTVQGKLNLLAEKMHQYHQ----LYKEWQQHEGQIRTVRSACEALRegvarchl 661
Cdd:TIGR02168 654 LVRPggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKalaeLRKELEELEEELEQLRKELEELS-------- 725
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 662 lmQQVLAAKEQFELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAEAAIRKKE-KQLNDSVEQVRKEGEEVQS 740
Cdd:TIGR02168 726 --RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEiEELEAQIEQLKEELKALRE 803
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 741 RISGMQGEIRQLNSSIDELMLRKEQiadpehLPETIARQQATNQETERRLSTVEArllQQEQNRKKLKQLEQELTEKQET 820
Cdd:TIGR02168 804 ALDELRAELTLLNEEAANLRERLES------LERRIAATERRLEDLEEQIEELSE---DIESLAAEIEELEELIEELESE 874
|
....*..
gi 695336968 821 ANRWGKL 827
Cdd:TIGR02168 875 LEALLNE 881
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
181-797 |
3.29e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 57.64 E-value: 3.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 181 RESAKA----ELLEKLTGTEIYSRIsseiyLRSKTADAELNQLKSNATLIELLSEEEITLLRTEKESLTNLREQGSKALI 256
Cdd:COG1196 207 RQAEKAeryrELKEELKELEAELLL-----LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 257 DLNAQLSVLHTLKLQQEQrdkKVQDMRLDEEKSKKLREEYTRQSDSLIRfrgqceavqpDLSRARELDVQIQSLVSQSKQ 336
Cdd:COG1196 282 ELEEAQAEEYELLAELAR---LEQDIARLEERRRELEERLEELEEELAE----------LEEELEELEEELEELEEELEE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 337 VEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLTGEIelpvteetgLFLESVRNRLKEQEDQLAILQEKNEARVNRL 416
Cdd:COG1196 349 AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL---------LEALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 417 NAFGIEAVTDEQARWMQEQTRLQNARQQMLEWRKAGTEAERLKAQQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRL 496
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 497 FENARiAMGKDVRTLRQNLRENEPCPVCGgtdhpyrnEEQVVHSLYQNIEQEYQTASAEYQQLNNRNIALKQDLLHLSEL 576
Cdd:COG1196 500 EADYE-GFLEGVKAALLLAGLRGLAGAVA--------VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAK 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 577 SGEITvqlqaFLQEAEQKRPSSEEEQNpdyfekQLHTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGV 656
Cdd:COG1196 571 AGRAT-----FLPLDKIRARAALAAAL------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 657 ARCHLLMQQVLAAKEQFELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAEAAIRKKEKQLNDSVEQVRKEGE 736
Cdd:COG1196 640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 695336968 737 EVQSRISGMQGEIRQLNSSIDELMLRKEQIADPEHLPETIARQqatnQETERRLSTVEARL 797
Cdd:COG1196 720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL----EELERELERLEREI 776
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
5-376 |
3.32e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 54.25 E-value: 3.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 5 TIRLKNLASIEGTF-EIDFQaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTPRfsasveslymsDIGESR-VNQAD 82
Cdd:PHA02562 6 KIRYKNILSVGNQPiEIQLD-----KVKKTLITGKNGAGKSTMLEALTFALFGKPFR-----------DIKKGQlINSIN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 83 VKNILrrgtgegfAEVDFlgasghcyrsrwsvrRTGSRANGALRSQTIQVTDLTANQEL---QGTRKELLAQLVTLVGLT 159
Cdd:PHA02562 70 KKDLL--------VELWF---------------EYGEKEYYIKRGIKPNVFEIYCNGKLldeSASSKDFQKYFEQMLGMN 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 160 YEQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISS-------EIYLRSKTADAELN----QLKSNATLIEl 228
Cdd:PHA02562 127 YKSFKQIVVLGTAGYVPFMQLSAPARRKLVEDLLDISVLSEMDKlnkdkirELNQQIQTLDMKIDhiqqQIKTYNKNIE- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 229 lseeeitllrtEKESLTNLREQGSKALIDLNAQLSvlHTLKLQQEQRDKKVQDMRLDEEKS----KKLREEYTRQSDSLI 304
Cdd:PHA02562 206 -----------EQRKKNGENIARKQNKYDELVEEA--KTIKAEIEELTDELLNLVMDIEDPsaalNKLNTAAAKIKSKIE 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 305 RFR---------GQCEAVQPDLSRARELDVQIQSLVSQ-SKQVEEI------LQGAEKAANAQANKLQSVQGALHTSCHS 368
Cdd:PHA02562 273 QFQkvikmyekgGVCPTCTQQISEGPDRITKIKDKLKElQHSLEKLdtaideLEEIMDEFNEQSKKLLELKNKISTNKQS 352
|
....*...
gi 695336968 369 LKNLTGEI 376
Cdd:PHA02562 353 LITLVDKA 360
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
16-823 |
5.62e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 5.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 16 GTFEIDFQAEPlrSAGIFAISGPTGAGKSTILDALCLALY-DKTPRFSA----------SVESLYMSDIGESRVNQADVK 84
Cdd:COG4913 12 GTFDGVHTIDF--DGRGTLLTGDNGSGKSTLLDAIQTLLVpAKRPRFNKaandagksdrTLLSYVRGKYGSERDEAGTRP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 85 NILRRG----------TGEGFAEVDFLGA----------SGHCYR--------------SRWSVRRTGSRANGALRSQTI 130
Cdd:COG4913 90 VYLRPGdtwsaiaatfANDGSGQTVTLAQvfwlkgdassLGDVKRffviadgpldledfEEFAHGFDIRALKARLKKQGV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 131 QVTDltanqelqgTRKELLAQLVTLVGLTYEQFTRtvLLAQ-------NDFATFLKSresakaELLEKltgTEIYSRIss 203
Cdd:COG4913 170 EFFD---------SFSAYLARLRRRLGIGSEKALR--LLHKtqsfkpiGDLDDFVRE------YMLEE---PDTFEAA-- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 204 eiylrsktadaelNQLKSN-ATLIELlsEEEITLLRTEKESLTNLREQGSK---ALIDLNAQLSVLHTLKLQQEQRDKKV 279
Cdd:COG4913 228 -------------DALVEHfDDLERA--HEALEDAREQIELLEPIRELAERyaaARERLAELEYLRAALRLWFAQRRLEL 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 280 QDMRLDEekskkLREEYTRQSDSLIRFRGQCEAVQpdlSRARELDVQIQSlvSQSKQVEEiLQGAEKAANAQANKLQSVQ 359
Cdd:COG4913 293 LEAELEE-----LRAELARLEAELERLEARLDALR---EELDELEAQIRG--NGGDRLEQ-LEREIERLERELEERERRR 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 360 GALHTSCHSLknltgEIELPVTEETglfLESVRNRLKEQEDQLAILQEknearvnrlnafgieAVTDEQARWMQEQTRLQ 439
Cdd:COG4913 362 ARLEALLAAL-----GLPLPASAEE---FAALRAEAAALLEALEEELE---------------ALEEALAEAEAALRDLR 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 440 NARQQMLEwrkagtEAERLKAQQEEMGHKQEQMRKEITlltTRLSEKEAELKVL---------QRLFENA---------- 500
Cdd:COG4913 419 RELRELEA------EIASLERRKSNIPARLLALRDALA---EALGLDEAELPFVgelievrpeEERWRGAiervlggfal 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 501 -----------------RIAMGKDVRTLRqnlrenepcpvCGGTDHPYRNEEQVVHSLYQNIEQEYQTASAE-YQQLNNR 562
Cdd:COG4913 490 tllvppehyaaalrwvnRLHLRGRLVYER-----------VRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWlEAELGRR 558
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 563 NIALKQDllHLSELSGE---ITVQLQAFL-QEAEQKRPSSEEEQNPdYF----EKQLHTVQGKLNLLAEKMHQYHQLYKE 634
Cdd:COG4913 559 FDYVCVD--SPEELRRHpraITRAGQVKGnGTRHEKDDRRRIRSRY-VLgfdnRAKLAALEAELAELEEELAEAEERLEA 635
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 635 WQQHEGQIRTVRSACEALREgvarchllmqqvlaakEQFELLKTAEttareqfrvVSEQLITLRQERAPLLKGKsveDAE 714
Cdd:COG4913 636 LEAELDALQERREALQRLAE----------------YSWDEIDVAS---------AEREIAELEAELERLDASS---DDL 687
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 715 AAIRKKEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIAD-PEHLPETIARQQATNQETERRLSTV 793
Cdd:COG4913 688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDlARLELRALLEERFAAALGDAVEREL 767
|
890 900 910
....*....|....*....|....*....|.
gi 695336968 794 EARLL-QQEQNRKKLKQLEQELTEKQETANR 823
Cdd:COG4913 768 RENLEeRIDALRARLNRAEEELERAMRAFNR 798
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
701-844 |
8.19e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 52.94 E-value: 8.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 701 RAPLLKGKSVEDAeaaIRK-KEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELmlrKEQIADpehLPETIARQ 779
Cdd:COG2433 369 KARVIRGLSIEEA---LEElIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERL---EAEVEE---LEAELEEK 439
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695336968 780 QATNQETERRLSTV------------EARLLQQEQNR--KKLKQLEQELTEKQETANRWGKLNKLIGSADGTKFKVIAQ 844
Cdd:COG2433 440 DERIERLERELSEArseerreirkdrEISRLDREIERleRELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVEK 518
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
311-823 |
9.53e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 9.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 311 EAVQPDLSRA----RELDVQIQSLVSQSKQveeilqgAEKAANAQAnKLQSVQGALhtSCHSLKNLTGEIELpvTEETGL 386
Cdd:COG1196 182 EATEENLERLedilGELERQLEPLERQAEK-------AERYRELKE-ELKELEAEL--LLLKLRELEAELEE--LEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 387 FLESVRNRLKEQEDQLAILQEKNEARVNRLNAfGIEAVTDEQARWMQEQTRLQNARQQMLEWRK-AGTEAERLKAQQEEM 465
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELEL-ELEEAQAEEYELLAELARLEQDIARLEERRReLEERLEELEEELAEL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 466 GHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMGKDVRTLRQNLRENEpcpvcgGTDHPYRNEEQVVHSLYQNI 545
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE------ELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 546 EQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAE-----------QKRPSSEEEQNPDYFEKQLHTV 614
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEeeaeleeeeeaLLELLAELLEEAALLEAALAEL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 615 QGKL-------NLLAEKMHQYHQLYKEWQ------------QHEGQIRTVRSACEAL---REGVARCHLLMQQVLAAKEQ 672
Cdd:COG1196 483 LEELaeaaarlLLLLEAEADYEGFLEGVKaalllaglrglaGAVAVLIGVEAAYEAAleaALAAALQNIVVEDDEVAAAA 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 673 FELLKTA----------------ETTAREQFRVVSEQLITLRQERAPLLKGKS------------VEDAEAAIRKKEKQL 724
Cdd:COG1196 563 IEYLKAAkagratflpldkirarAALAAALARGAIGAAVDLVASDLREADARYyvlgdtllgrtlVAARLEAALRRAVTL 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 725 NDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIADPEHLpETIARQQATNQETERRLSTVEARLLQQEQNR 804
Cdd:COG1196 643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE-EELELEEALLAEEEEERELAEAEEERLEEEL 721
|
570
....*....|....*....
gi 695336968 805 KKLKQLEQELTEKQETANR 823
Cdd:COG1196 722 EEEALEEQLEAEREELLEE 740
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
11-64 |
1.20e-06 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 46.44 E-value: 1.20e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 695336968 11 LASIE----GTFeiDFQAEPLRSAGIFAISGPTGAGKSTILDALCLALY-DKTPRFSAS 64
Cdd:pfam13555 1 LTRLQlinwGTF--DGHTIPIDPRGNTLLTGPSGSGKSTLLDAIQTLLVpAKRARFNKA 57
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
6-513 |
1.60e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 1.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 6 IRLKNLASIEGTFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTprfSASVESLYMSDIgesrVNQADvkn 85
Cdd:TIGR02169 5 IELENFKSFGKKKVIPF------SKGFTVISGPNGSGKSNIGDAILFALGLSS---SKAMRAERLSDL----ISNGK--- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 86 ilrRGTGEGFAEVDFL-----GASGHCYRSRWSVRRT--GSRANGALRSQTIQVTDLtanqelqgtrKELLAQLvtlvGL 158
Cdd:TIGR02169 69 ---NGQSGNEAYVTVTfknddGKFPDELEVVRRLKVTddGKYSYYYLNGQRVRLSEI----------HDFLAAA----GI 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 159 TYEqfTRTVLLaQNDFATFLKSRESAKAELLEKLTGTEIYSRisseiylRSKTADAELNQLKSNATLIELLSEE---EIT 235
Cdd:TIGR02169 132 YPE--GYNVVL-QGDVTDFISMSPVERRKIIDEIAGVAEFDR-------KKEKALEELEEVEENIERLDLIIDEkrqQLE 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 236 LLRTEKESLTNLRE-QGSKALIDLNAQLSVLHTLKLQQEQRDKKVQDMRLDEEKSKKLREEYTRQSDSLIRFRGQCEAVQ 314
Cdd:TIGR02169 202 RLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKI 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 315 PDLSRARELDVQ--IQSLVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLTGEIelpvtEETGLFLESVR 392
Cdd:TIGR02169 282 KDLGEEEQLRVKekIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREI-----EEERKRRDKLT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 393 NRLKEQEDQLAILQEKnearvnrlnafgIEAVTDEQARW----MQEQTRLQNARQQM----LEWRKAGTEAERLKAQQEE 464
Cdd:TIGR02169 357 EEYAELKEELEDLRAE------------LEEVDKEFAETrdelKDYREKLEKLKREInelkRELDRLQEELQRLSEELAD 424
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 695336968 465 MGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMGKDVRTLRQ 513
Cdd:TIGR02169 425 LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1-835 |
1.84e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 52.21 E-value: 1.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 1 MKILTIRLKNLASIEGTfEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYdktprfsasveslymsdiGESRVNQ 80
Cdd:PRK01156 1 MIIKRIRLKNFLSHDDS-EIEF------DTGINIITGKNGAGKSSIVDAIRFALF------------------TDKRTEK 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 81 adVKNILRRGTGEGFAEVDFLgASGHCYRSRWSVRRtgsRANGALRSQTIQVTDLTANQELQGTRKELLAQlvtLVGLTY 160
Cdd:PRK01156 56 --IEDMIKKGKNNLEVELEFR-IGGHVYQIRRSIER---RGKGSRREAYIKKDGSIIAEGFDDTTKYIEKN---ILGISK 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 161 EQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRisseIYLRSKTAdaeLNQLKSNATLIELLSEEeitlLRTE 240
Cdd:PRK01156 127 DVFLNSIFVGQGEMDSLISGDPAQRKKILDEILEINSLER----NYDKLKDV---IDMLRAEISNIDYLEEK----LKSS 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 241 KESLTNLreqgSKALIDLNAQLSVLHTlklQQEQRDKKVQDMRLDEEKSKKLREEYTRQSDSLIRFRGQCEAVQPDLSRA 320
Cdd:PRK01156 196 NLELENI----KKQIADDEKSHSITLK---EIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSME 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 321 RELDVQIQSLVSQSKqveEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLTGEI--------ELPVTEETGLFLESVR 392
Cdd:PRK01156 269 LEKNNYYKELEERHM---KIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEInkyhaiikKLSVLQKDYNDYIKKK 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 393 NRLKEQEDQLAILQEKNEARVNRLNAfgIEAVTDEQARWMQEQTRLQNARQQMLewRKAGTEAERLKAQQEEMGHKQEQM 472
Cdd:PRK01156 346 SRYDDLNNQILELEGYEMDYNSYLKS--IESLKKKIEEYSKNIERMSAFISEIL--KIQEIDPDAIKKELNEINVKLQDI 421
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 473 RKEITLLTTR---LSEKEAELKvlqrlfENARIAMGKDVrtlrqnlrenepCPVCGGTDHPYRNEEQVVHslYQN----I 545
Cdd:PRK01156 422 SSKVSSLNQRiraLRENLDELS------RNMEMLNGQSV------------CPVCGTTLGEEKSNHIINH--YNEkksrL 481
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 546 EQEYQTASAEYQQLNNRNIALKQdllHLSELSGEITVQLQAFLQEAEQKRpsseeeqnpdyfeKQLHTVQGKLNLLAEKM 625
Cdd:PRK01156 482 EEKIREIEIEVKDIDEKIVDLKK---RKEYLESEEINKSINEYNKIESAR-------------ADLEDIKIKINELKDKH 545
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 626 HQYHQLYKEWQQ-HEGQIRTVRSacealregvarchllmqQVLAAKEQFELLKTaeTTAREQFRVVSEQLITLRQERAPL 704
Cdd:PRK01156 546 DKYEEIKNRYKSlKLEDLDSKRT-----------------SWLNALAVISLIDI--ETNRSRSNEIKKQLNDLESRLQEI 606
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 705 LKG------------KSVEDAEAAIRKKEKQLND---SVEQVRKEGEEVQSRISGMQGEIRQLNssidELMLRKEQIADp 769
Cdd:PRK01156 607 EIGfpddksyidksiREIENEANNLNNKYNEIQEnkiLIEKLRGKIDNYKKQIAEIDSIIPDLK----EITSRINDIED- 681
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695336968 770 eHLPETIARQQATNQETERRLSTVEArllqqeqNRKKLKQLEQELTEKQETANRWGKLNKLIGSAD 835
Cdd:PRK01156 682 -NLKKSRKALDDAKANRARLESTIEI-------LRTRINELSDRINDINETLESMKKIKKAIGDLK 739
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
3-93 |
2.26e-06 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 49.53 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 3 ILTIRLKNLASIEGTFEIDFQAeplrsaGIFAISGPTGAGKSTILDALCLALYDKTPRFSASVESLyMSDIGESRVnQAD 82
Cdd:cd03240 1 IDKLSIRNIRSFHERSEIEFFS------PLTLIVGQNGAGKTTIIEALKYALTGELPPNSKGGAHD-PKLIREGEV-RAQ 72
|
90
....*....|.
gi 695336968 83 VKNILRRGTGE 93
Cdd:cd03240 73 VKLAFENANGK 83
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
318-800 |
3.43e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 51.19 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 318 SRARELDVQIQSLVSQSKQVEEILQGAEKAANAQANKLQsvqgALHTSCHSLKNLTGEIELPVTEEtglflESVRNRLKE 397
Cdd:PRK02224 213 SELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE----ELETLEAEIEDLRETIAETERER-----EELAEEVRD 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 398 QEDQLAILQEKNEARVNR--LNAFGIEAVTDEQA-----------RWMQEQTRLQNARQQMLEWRKAG----TEAERLKA 460
Cdd:PRK02224 284 LRERLEELEEERDDLLAEagLDDADAEAVEARREeledrdeelrdRLEECRVAAQAHNEEAESLREDAddleERAEELRE 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 461 QQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMGK------------------------DVRTLRQNLR 516
Cdd:PRK02224 364 EAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNaedfleelreerdelrereaeleaTLRTARERVE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 517 ENE------PCPVCG----GTDHPYRNEEQvvhslyqniEQEYQTASAEYQQLNNRNIALKQDLLHLSELsgeitVQLQA 586
Cdd:PRK02224 444 EAEalleagKCPECGqpveGSPHVETIEED---------RERVEELEAELEDLEEEVEEVEERLERAEDL-----VEAED 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 587 FLQEAEQKRPSSEEeqnpdYFEKQLHTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQV 666
Cdd:PRK02224 510 RIERLEERREDLEE-----LIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 667 LAAKEQFELLKT-----AETTAR-EQFRVVSEQLITLRQERAPLLKGKS---------VEDA--EAAIRKKEK------Q 723
Cdd:PRK02224 585 KERIESLERIRTllaaiADAEDEiERLREKREALAELNDERRERLAEKRerkreleaeFDEAriEEAREDKERaeeyleQ 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 724 LNDSVEQVRKEGEEVQSRISGMQGEIRQLNSsidelmLRKEQiadpEHLPETIARQQATNQETERRLST---VEARLLQQ 800
Cdd:PRK02224 665 VEEKLDELREERDDLQAEIGAVENELEELEE------LRERR----EALENRVEALEALYDEAEELESMygdLRAELRQR 734
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
277-844 |
3.76e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 3.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 277 KKVQDMRLDEEKSKKLREEytRQSDSLIRFRgqcEAVQPDLSRAreldvQIQSLVSQSKQVEEILQGAEKAANAQANKLQ 356
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAEEE--RNNEEIRKFE---EARMAHFARR-----QAAIKAEEARKADELKKAEEKKKADEAKKAE 1299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 357 SVQGALHTSCHSLKNLTGEIELPVTEETGLFLESVRNRLKEQEDQLAILQEKNEARVNRLNAFGIEAVTDEQARwMQEQT 436
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK-EEAKK 1378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 437 RLQNARQQMLEWRKAgteaERLKAQQEEMGHKQEQMRK--EITLLTTRLSEKEAELKVLQRLFENARIAmgKDVRTLRQN 514
Cdd:PTZ00121 1379 KADAAKKKAEEKKKA----DEAKKKAEEDKKKADELKKaaAAKKKADEAKKKAEEKKKADEAKKKAEEA--KKADEAKKK 1452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 515 LRENEPCPVCGGTDHPYRNEEQVVHSLYQNIEQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQA-FLQEAEQ 593
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdEAKKAEE 1532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 594 KRpSSEEEQNPDYFEKQLHTVQGKLNLLAEKMHQYHQLYKEwqqHEGQIRTVRSACEALREGVARchllMQQVLAAKEQF 673
Cdd:PTZ00121 1533 AK-KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA---EEDKNMALRKAEEAKKAEEAR----IEEVMKLYEEE 1604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 674 ELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAEA----AIRKKEKQLNDSVEQVRKEGEEVQSRISGMQGEI 749
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKkkaeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 750 RQLNSSIDELMLRKEQIADPEHL----PETIARQQATNQETERRLSTVEARLLQQEQNRKKLKQLEQELTEKQETANRWG 825
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELkkkeAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKK 1764
|
570
....*....|....*....
gi 695336968 826 KLNKLIGSADGTKFKVIAQ 844
Cdd:PTZ00121 1765 EEEKKAEEIRKEKEAVIEE 1783
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
388-760 |
9.76e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 9.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 388 LESVRNRLKEQEDQLAILQEK-NEARVNRLNAfgIEAVTDEQARWMQEQTRLQNARQQMlewRKAGTEAERLKAQQEEMG 466
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKAlAELRKELEEL--EEELEQLRKELEELSRQISALRKDL---ARLEAEVEQLEERIAQLS 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 467 HKQEQMRKEITLLTTRLSEKEAELKVL--QRLFENARIAMGKD-VRTLRQNLREnepcpvcggtdhpyrneeqvVHSLYQ 543
Cdd:TIGR02168 754 KELTELEAEIEELEERLEEAEEELAEAeaEIEELEAQIEQLKEeLKALREALDE--------------------LRAELT 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 544 NIEQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAEqkrpssEEEQNPDYFEKQLhtvQGKLNLLAE 623
Cdd:TIGR02168 814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE------ELEELIEELESEL---EALLNERAS 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 624 KMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQFEL-LKTAETTAREQFRVVSEQLITLRQERA 702
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVrIDNLQERLSEEYSLTLEEAEALENKIE 964
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 695336968 703 PllkgkSVEDAEAAIRKKEKQLN-------DSVEqvrkEGEEVQSRISGMQGEIRQLNSSIDELM 760
Cdd:TIGR02168 965 D-----DEEEARRRLKRLENKIKelgpvnlAAIE----EYEELKERYDFLTAQKEDLTEAKETLE 1020
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2-822 |
1.96e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.81 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 2 KILTIRLKNLASIEGTFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTprfSASVESLYMSDI----GESR 77
Cdd:pfam02463 1 YLKRIEIEGFKSYAKTVILPF------SPGFTAIVGPNGSGKSNILDAILFVLGERS---AKSLRSERLSDLihskSGAF 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 78 VNQADVKNILrrgtgegfaevDFLGASGHCYRSRWSVRRTGSRANGalrsqtiqvTDLTANQELqGTRKELLAQLVTlVG 157
Cdd:pfam02463 72 VNSAEVEITF-----------DNEDHELPIDKEEVSIRRRVYRGGD---------SEYYINGKN-VTKKEVAELLES-QG 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 158 LTYEQFTrtvLLAQNDFATFLKSR-ESAKAELLEKLTGTEIYSRISSeiylRSKTADAELNQLKSNATLIELLSEEEITL 236
Cdd:pfam02463 130 ISPEAYN---FLVQGGKIEIIAMMkPERRLEIEEEAAGSRLKRKKKE----ALKKLIEETENLAELIIDLEELKLQELKL 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 237 LRTEKESLTNLREQGSKALIDLNaqLSVLHTLKLQQEQRDKKVQDMRLDEEKSKKLREEYTRQSDSLIR---FRGQCEAV 313
Cdd:pfam02463 203 KEQAKKALEYYQLKEKLELEEEY--LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQvlkENKEEEKE 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 314 QPDL--------SRARELDVQIQSLVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSCHSLKNLTGEIELPVTEETG 385
Cdd:pfam02463 281 KKLQeeelkllaKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 386 LFLESVRNRLKEQEDQ--LAILQEKNEARVNRLN------AFGIEAVTDEQARWMQEQTRLQNARQQMLEWRKAGTEAER 457
Cdd:pfam02463 361 LEKLQEKLEQLEEELLakKKLESERLSSAAKLKEeelelkSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 458 LK----AQQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMGKDVRTLRQNLRENEpcPVCGGTDHPYRN 533
Cdd:pfam02463 441 LKqgklTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR--SGLKVLLALIKD 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 534 EEQVVHSLYQNIEQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITVQ--LQAFLQEAEQKRPSSEEEQNPDYFEKQL 611
Cdd:pfam02463 519 GVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRalTELPLGARKLRLLIPKLKLPLKSIAVLE 598
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 612 HTVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQFELLKTAETTAREQFRVVS 691
Cdd:pfam02463 599 IDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEI 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 692 EQLITLR-QERAPLLKGKSVEDAEAAIRKKEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNSSIDELMLRKEQIADPE 770
Cdd:pfam02463 679 QELQEKAeSELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK 758
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 695336968 771 HLPETIARQQATNQETERRLSTVEA-RLLQQEQNRKKLKQLEQELTEKQETAN 822
Cdd:pfam02463 759 KEEKEEEKSELSLKEKELAEEREKTeKLKVEEEKEEKLKAQEEELRALEEELK 811
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
135-797 |
3.54e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 3.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 135 LTANQELQGTRKELLAQLVTLVGLTYEQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADA 214
Cdd:TIGR02168 321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 215 ELNQLKS--------NATLIELLSEEEITLLRTEKESLTNLREQGSKALIDLNAQLSVLHT-LKLQQEQRDKKVQDMRLD 285
Cdd:TIGR02168 401 EIERLEArlerledrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEaLEELREELEEAEQALDAA 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 286 EEKSKKLREEYTRQSDSLIRFRGQCEAVQPDLSRARELDvQIQSLVSQSKQVEEILQGAEKAA---NAQA---NKLQSVQ 359
Cdd:TIGR02168 481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLS-GILGVLSELISVDEGYEAAIEAAlggRLQAvvvENLNAAK 559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 360 GALHTSCHSLKNLTGEIELPVTEETGLfLESVRNRLKEQEDQLAILQE----KNEARVNRLNAFGIEAVTD------EQA 429
Cdd:TIGR02168 560 KAIAFLKQNELGRVTFLPLDSIKGTEI-QGNDREILKNIEGFLGVAKDlvkfDPKLRKALSYLLGGVLVVDdldnalELA 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 430 RWMQEQTRL------------------QNARQQMLEWRKAGTEAERLKAQQEEmghKQEQMRKEITLLTTRLSEKEAELK 491
Cdd:TIGR02168 639 KKLRPGYRIvtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIEELEE---KIAELEKALAELRKELEELEEELE 715
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 492 VLQRLFENARIamgkDVRTLRQNLRENEpcpvcggtdhpyrNEEQVVHSLYQNIEQEYQTASAEYQQLNNRniaLKQDLL 571
Cdd:TIGR02168 716 QLRKELEELSR----QISALRKDLARLE-------------AEVEQLEERIAQLSKELTELEAEIEELEER---LEEAEE 775
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 572 HLSELSGEItVQLQAFLQEAEQKRPSSEEEQnpDYFEKQLHTVQGKLNLLAEKMHQYHQLYKEWQQhegQIRTVRSACEA 651
Cdd:TIGR02168 776 ELAEAEAEI-EELEAQIEQLKEELKALREAL--DELRAELTLLNEEAANLRERLESLERRIAATER---RLEDLEEQIEE 849
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 652 LREgvarchllmqQVLAAKEQFELLKTAETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAE-AAIRKKEKQLNDSVEQ 730
Cdd:TIGR02168 850 LSE----------DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEElRELESKRSELRRELEE 919
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 695336968 731 VRKEGEEVQSRISGMQGEIRQLNSsidelMLRKEQIADPEHLPETIARQQATNQETERRLSTVEARL 797
Cdd:TIGR02168 920 LREKLAQLELRLEGLEVRIDNLQE-----RLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
176-600 |
4.46e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.41 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 176 TFLKSRESAKAELLE---KLTGTEIYSRISSEIYLRSKTADAELNQLKSNATLIEL-----LSEEEITLLRTEKES---- 243
Cdd:pfam05483 260 TFLLEESRDKANQLEektKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALeedlqIATKTICQLTEEKEAqmee 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 244 LTNLREQGSKALIDLNAQLSVLHTLKLQQEQRDKKvqdmrlDEEKSKKLREEYTRQSDSLIRFRGQCEAVQPDLSRAREL 323
Cdd:pfam05483 340 LNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEK------NEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKI 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 324 DVQIQSLVSQSKQVEEI---LQGAEkaanaqanklQSVQGALHTSCHSLKNLTGEIELPVTEEtglflESVRNRLKEQED 400
Cdd:pfam05483 414 LAEDEKLLDEKKQFEKIaeeLKGKE----------QELIFLLQAREKEIHDLEIQLTAIKTSE-----EHYLKEVEDLKT 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 401 QLAILQEKNEARVNRLNAFGIE--AVTDEQARWMQEqtrLQNARQQMLEWRKagtEAERLKAQQEEMGHKQEQMRKEITL 478
Cdd:pfam05483 479 ELEKEKLKNIELTAHCDKLLLEnkELTQEASDMTLE---LKKHQEDIINCKK---QEERMLKQIENLEEKEMNLRDELES 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 479 LTTRLSEKEAELKV-LQRLFENARiamGKDVRTLRQNLRENEPCPVCGGTDHPYRNEEQVVHSLYQNIEQEYQTASAEYQ 557
Cdd:pfam05483 553 VREEFIQKGDEVKCkLDKSEENAR---SIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENK 629
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 695336968 558 QLNNRNIALKQDLLHLSELSGEITVQLQAFLQEAEQKRPSSEE 600
Cdd:pfam05483 630 QLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEK 672
|
|
| ABC_RecN |
cd03241 |
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ... |
3-201 |
1.11e-04 |
|
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213208 [Multi-domain] Cd Length: 276 Bit Score: 45.27 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 3 ILTIRLKNLASIEgTFEIDFQAeplrsaGIFAISGPTGAGKSTILDALCLALYDKTprfsasveslyMSDIGESRVNQAD 82
Cdd:cd03241 1 LLELSIKNFALIE-ELELDFEE------GLTVLTGETGAGKSILLDALSLLLGGRA-----------SADLIRSGAEKAV 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 83 VKNI--LRRGTGEGFAEVDFLGASGHCYRSRWSVRRTG-SRA--NGalrsQTIQVTDLtanqelqgtrKELLAQLVTLVG 157
Cdd:cd03241 63 VEGVfdISDEEEAKALLLELGIEDDDDLIIRREISRKGrSRYfiNG----QSVTLKLL----------RELGSLLVDIHG 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 695336968 158 LTYEQ------FTRTVLLAQNDFATFLKS--RESAKAELLEKLTGTEIySRI 201
Cdd:cd03241 129 QHDHQnllnpeRQLDLLDGGLDDVEFLFStnPGEPLKPLAKIASGGEL-SRL 179
|
|
| COG1106 |
COG1106 |
ATPase/GTPase, AAA15 family [General function prediction only]; |
3-50 |
2.18e-04 |
|
ATPase/GTPase, AAA15 family [General function prediction only];
Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 44.65 E-value: 2.18e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 695336968 3 ILTIRLKNLASIEGTFEIDFQAEPLRSAGIFAISGPTGAGKSTILDAL 50
Cdd:COG1106 2 LISFSIENFRSFKDELTLSMVASGLRLLRVNLIYGANASGKSNLLEAL 49
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
1-54 |
2.72e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 44.22 E-value: 2.72e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 695336968 1 MKILTIRLKNLASIEGtFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLAL 54
Cdd:COG3593 1 MKLEKIKIKNFRSIKD-LSIEL------SDDLTVLVGENNSGKSSILEALRLLL 47
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
249-816 |
6.24e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.67 E-value: 6.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 249 EQGSKALIDLNAQLSVLH----TLKLQQEQRDKKVQDMRLD-EEKSKKLREEYTRQSDSLirfRGQCEAVQPDLSRAREl 323
Cdd:pfam12128 247 QQEFNTLESAELRLSHLHfgykSDETLIASRQEERQETSAElNQLLRTLDDQWKEKRDEL---NGELSAADAAVAKDRS- 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 324 dvQIQSLVSQSKQVEEIlqGAEKAAnAQANKLQSVQGALHTSCHSLKNLTGEI----------ELPVTEETGLFLESVRN 393
Cdd:pfam12128 323 --ELEALEDQHGAFLDA--DIETAA-ADQEQLPSWQSELENLEERLKALTGKHqdvtakynrrRSKIKEQNNRDIAGIKD 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 394 RLKEQEDQLAILQEKNEARVNRLNAFGIEAVTDEQARWMQEQTRLQNArqqmLEWRK----AGTEAERLKAQQEEMGHKQ 469
Cdd:pfam12128 398 KLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSR----LGELKlrlnQATATPELLLQLENFDERI 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 470 EQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMG--------------------------------KDVRTLRQNLRE 517
Cdd:pfam12128 474 ERAREEQEAANAEVERLQSELRQARKRRDQASEALRqasrrleerqsaldelelqlfpqagtllhflrKEAPDWEQSIGK 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 518 NEPCPVCGGTD-HPYRNEEQVV--------------------HSLYQNIEQEYQTASAEYQQLNNRNIALKQDLLHLS-- 574
Cdd:pfam12128 554 VISPELLHRTDlDPEVWDGSVGgelnlygvkldlkridvpewAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANge 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 575 --ELSGEITVQLQAF------------LQEAEQKRPSSEEEQNPDYFEKQLHTVQGKLNLLAEKmhqyHQLYKEWQQheG 640
Cdd:pfam12128 634 leKASREETFARTALknarldlrrlfdEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK----HQAWLEEQK--E 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 641 QIRTVRSACEALREGVarchllmqqVLAAKEQFELLKTAETTAREQFRVvseQLITLRQERAPLLKGKSVEDAEAAIRKK 720
Cdd:pfam12128 708 QKREARTEKQAYWQVV---------EGALDAQLALLKAAIAARRSGAKA---ELKALETWYKRDLASLGVDPDVIAKLKR 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 721 E-KQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNssiDELMLRKEQI-ADPEHLPETIARQQAtnqETERRLStvearll 798
Cdd:pfam12128 776 EiRTLERKIERIAVRRQEVLRYFDWYQETWLQRR---PRLATQLSNIeRAISELQQQLARLIA---DTKLRRA------- 842
|
650
....*....|....*...
gi 695336968 799 QQEQNRKKLKQLEQELTE 816
Cdd:pfam12128 843 KLEMERKASEKQQVRLSE 860
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
591-818 |
7.14e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 7.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 591 AEQKRPSSEEEQNPDYF-----EKQLHTV-QGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSAC-------EALREGVA 657
Cdd:pfam17380 337 AEQERMAMERERELERIrqeerKRELERIrQEEIAMEISRMRELERLQMERQQKNERVRQELEAArkvkileEERQRKIQ 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 658 RCHLLMQQVLAAKE---QFELLKTAETTAREQFRVVSEQLitLRQERAPLLKGKSVEdaeaaiRKKEKQLNDSVEQVRKE 734
Cdd:pfam17380 417 QQKVEMEQIRAEQEearQREVRRLEEERAREMERVRLEEQ--ERQQQVERLRQQEEE------RKRKKLELEKEKRDRKR 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 735 GEEVQSRIsgMQGEIRQLNSSIDELMlRKEQIADPEhlpeTIARQQATNQETERRLSTVEARLLQQEQNRKKLKQLEQEL 814
Cdd:pfam17380 489 AEEQRRKI--LEKELEERKQAMIEEE-RKRKLLEKE----MEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKA 561
|
....
gi 695336968 815 TEKQ 818
Cdd:pfam17380 562 TEER 565
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
161-466 |
8.07e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 8.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 161 EQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGTEIYSRISSEIYLRSKTADAELNQLksnatliellsEEEITLLRTE 240
Cdd:TIGR02168 687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-----------EERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 241 KESLTNLREQGSKALIDLNAQLSVLHTLKLQQEQRDKKVQD-MRLDEEKSKKLREEYTRQSdslIRFRGQCEAVQPDLSR 319
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEeLKALREALDELRAELTLLN---EEAANLRERLESLERR 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 320 ARELDVQIQSLVSQSKQVEEILQgaekAANAQANKLQSVQGALHTSCHSLKNLTGEIELPVT------EETGLFLESVRN 393
Cdd:TIGR02168 833 IAATERRLEDLEEQIEELSEDIE----SLAAEIEELEELIEELESELEALLNERASLEEALAllrselEELSEELRELES 908
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 695336968 394 RLKEQEDQLAILQEKNEARVNRLNAFGIEAVTDEQARWMQEQTRLQNARQQM----LEWRKAGTEAERLKAQQEEMG 466
Cdd:TIGR02168 909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEnkieDDEEEARRRLKRLENKIKELG 985
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
153-819 |
8.88e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 8.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 153 VTLVGLTYEQFTRTVLLAQNDFATFLKSRESAKAELLEKLTGteiysrISSEIYLRSKTADAELNQLKSNATLIELLSEE 232
Cdd:TIGR00606 396 HTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKG------LGRTIELKKEILEKKQEELKFVIKELQQLEGS 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 233 EITLLRTEKESLTNLREQgSKALIDLNAQLSVLHTLKLQQEQRDKKVQDMRLDEEKSKKLREEYTR-QSDSL-------- 303
Cdd:TIGR00606 470 SDRILELDQELRKAEREL-SKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRtQMEMLtkdkmdkd 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 304 -----IRFRGQCEAVQ--PDLSRARELDVQIQSLVSQSKQVEEIL-------QGAEKAANAQANKLQSVQGALHTSCHSL 369
Cdd:TIGR00606 549 eqirkIKSRHSDELTSllGYFPNKKQLEDWLHSKSKEINQTRDRLaklnkelASLEQNKNHINNELESKEEQLSSYEDKL 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 370 KNLTGEIELPVTeetglfLESVRNRLKEQEDQLAILQekneARVNRLNAFgIEAVTDEQA-------RWMQEQTRLQNAR 442
Cdd:TIGR00606 629 FDVCGSQDEESD------LERLKEEIEKSSKQRAMLA----GATAVYSQF-ITQLTDENQsccpvcqRVFQTEAELQEFI 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 443 QQML-EWRKAGTEAERLKAQQEEMGHKQEQMRKEITLLTTRLSEKEAELKVLQRLFENariaMGKDVRTLRQNLRENEPC 521
Cdd:TIGR00606 698 SDLQsKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQK----VNRDIQRLKNDIEEQETL 773
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 522 PvcgGTDHPYRNEEQVVHSLYQNIEQEYqtasaEYQQLNNRNIAlkqdllhlselsgeitvQLQAFLQEAEQKRPSSEEE 601
Cdd:TIGR00606 774 L---GTIMPEEESAKVCLTDVTIMERFQ-----MELKDVERKIA-----------------QQAAKLQGSDLDRTVQQVN 828
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 602 QNPDYFEKQLHTVQGKLNLLaEKMHQYHQlyKEWQQHEGQIRTVRSACEALREGVARCHLLMQQVLAAKEQFELLKTAET 681
Cdd:TIGR00606 829 QEKQEKQHELDTVVSKIELN-RKLIQDQQ--EQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 682 TAREQFRVVSEQLITLRQERAPLLKGKSVEDAEAA-----IRKK-----------EKQLNDSVEQVRKEGEEVQSRISGM 745
Cdd:TIGR00606 906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQdkvndIKEKvknihgymkdiENKIQDGKDDYLKQKETELNTVNAQ 985
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695336968 746 QGEIRQLNSSIDELMLRKEQIADPEHLPETIARQQATNQETERRLSTVEARLLQ--QEQNRKKLKQLEQELTEKQE 819
Cdd:TIGR00606 986 LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQhlKEMGQMQVLQMKQEHQKLEE 1061
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
579-823 |
1.11e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 579 EITVQLQAFLQEA--EQKRPSSEEEQNPDYFEKQLHTVQGKLNLLAEKMhqyhqlyKEWQQHEGQIRTVRSACEALREGV 656
Cdd:TIGR00606 695 EFISDLQSKLRLApdKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE-------KEIPELRNKLQKVNRDIQRLKNDI 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 657 ARCHLLMQQVLAAKEQFELLKTaETTAREQFRVVSEQLITLRQERAPLLKGKSVEDAEAAIRKKEKQLNDSVEQVRKEGE 736
Cdd:TIGR00606 768 EEQETLLGTIMPEEESAKVCLT-DVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIE 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 737 EVQSRISGMQGEIRQLNSSIDELMLRKEQIADPEHLPETIARQQATN----QETERRLSTVEARLLQQEQNRKKLKQLEQ 812
Cdd:TIGR00606 847 LNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELstevQSLIREIKDAKEQDSPLETFLEKDQQEKE 926
|
250
....*....|.
gi 695336968 813 ELTEKQETANR 823
Cdd:TIGR00606 927 ELISSKETSNK 937
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
891-960 |
1.47e-03 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.15 E-value: 1.47e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 891 VYSLSGGESFLISLAlalglsslssnnlKVESLFIDegFGSLDADSLRTVMEALEQLQmqgrkigVISHV 960
Cdd:COG0419 156 IETLSGGERLRLALA-------------DLLSLILD--FGSLDEERLERLLDALEELA-------IITHV 203
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
3-90 |
1.73e-03 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 40.37 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 3 ILTIRLKNLASIEGTFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLALYDKTPRFSASVESLYMSDIGESRVNQAD 82
Cdd:cd03239 1 IKQITLKNFKSYRDETVVGG------SNSFNAIVGPNGSGKSNIVDAICFVLGGKAAKLRRGSLLFLAGGGVKAGINSAS 74
|
....*...
gi 695336968 83 VKNILRRG 90
Cdd:cd03239 75 VEITFDKS 82
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
289-581 |
2.15e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 2.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 289 SKKLREEYTRQSDSLIRFRGQCEAVQPDLSRARELDVQIQSLVSQSKQVEEILQGAEKAANAQANKLQSVQGALHTSchs 368
Cdd:TIGR02169 669 SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED--- 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 369 LKNLTGEIELPVTEetglfLESVRNRLKEQEDQLAILQEKNEARVNRLNAFGIEAVTDEqARWMQEQTRLQNARQQMLEw 448
Cdd:TIGR02169 746 LSSLEQEIENVKSE-----LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAE-LSKLEEEVSRIEARLREIE- 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 449 RKAGTEAERLKAQQEEMGHKQEQM----------RKEITLLTTRLSEKEAELKVLQ---RLFENARIAMGKDVRTLRQNL 515
Cdd:TIGR02169 819 QKLNRLTLEKEYLEKEIQELQEQRidlkeqiksiEKEIENLNGKKEELEEELEELEaalRDLESRLGDLKKERDELEAQL 898
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 695336968 516 REnepcpvcggtdhpyrneeqvvhslyqnIEQEYQTASAEYQQLNNRniaLKQDLLHLSELSGEIT 581
Cdd:TIGR02169 899 RE---------------------------LERKIEELEAQIEKKRKR---LSELKAKLEALEEELS 934
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
32-60 |
2.80e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 39.65 E-value: 2.80e-03
10 20
....*....|....*....|....*....
gi 695336968 32 IFAISGPTGAGKSTILDALCLALYDKTPR 60
Cdd:cd03227 23 LTIITGPNGSGKSTILDAIGLALGGAQSA 51
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
470-759 |
3.43e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 3.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 470 EQMRKEITLLTTRLSEKEAELKVLQRLFENARIAMGK------------DVRTLRQNLREnepcpvcggtdhpyrneeqv 537
Cdd:PRK04863 789 EQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGShlavafeadpeaELRQLNRRRVE-------------------- 848
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 538 vhslyqnIEQEYQTASAEYQQLNNRNIALKQDLLHLSELSGEITV----QLQAFLQEAEQKRPSSEE-EQNPDYFEKQLH 612
Cdd:PRK04863 849 -------LERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLladeTLADRVEEIREQLDEAEEaKRFVQQHGNALA 921
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 613 TVQGKLNLLAEKMHQYHQLYKEWQQHEGQIRTVRSACEALREGVARCHLL----MQQVLAA--------KEQFELLKTAE 680
Cdd:PRK04863 922 QLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFsyedAAEMLAKnsdlneklRQRLEQAEQER 1001
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 681 TTAREQFRVVSEQLI--------------TLRQERAPLLKGKS------VEDAEAAIRKKEKQLNDSVEQVRKEGEEVQS 740
Cdd:PRK04863 1002 TRAREQLRQAQAQLAqynqvlaslkssydAKRQMLQELKQELQdlgvpaDSGAEERARARRDELHARLSANRSRRNQLEK 1081
|
330
....*....|....*....
gi 695336968 741 RISGMQGEIRQLNSSIDEL 759
Cdd:PRK04863 1082 QLTFCEAEMDNLTKKLRKL 1100
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
923-971 |
3.93e-03 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 39.15 E-value: 3.93e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 695336968 923 LFIDEGFGSLDADSLRTVMEALEQLQMQGRKIGVISHVQEMSERIAVQV 971
Cdd:cd00267 102 LLLDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRV 150
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
27-55 |
4.00e-03 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 39.15 E-value: 4.00e-03
10 20
....*....|....*....|....*....
gi 695336968 27 LRSAGIFAISGPTGAGKSTILDALCLALY 55
Cdd:cd00267 22 LKAGEIVALVGPNGSGKSTLLRAIAGLLK 50
|
|
| ABC_SMC_barmotin |
cd03278 |
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
6-54 |
4.04e-03 |
|
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 39.76 E-value: 4.04e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 695336968 6 IRLKNLASIEGTFEIDFqaeplrSAGIFAISGPTGAGKSTILDALCLAL 54
Cdd:cd03278 4 LELKGFKSFADKTTIPF------PPGLTAIVGPNGSGKSNIIDAIRWVL 46
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
546-817 |
6.10e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.71 E-value: 6.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 546 EQEYQTASAEYQQLNNRNIALKQ------DLLHLS---ELSGEITVQLQAFLQEAEQKRPSSEEEQnpDYFEKQLHTVQG 616
Cdd:PRK04863 327 EQDYQAASDHLNLVQTALRQQEKieryqaDLEELEerlEEQNEVVEEADEQQEENEARAEAAEEEV--DELKSQLADYQQ 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 617 KLNLLAEKMHQYHQLYKEWQQHEGQIR----TVRSACEALREGVARCHLLMQQVLAAKEQfelLKTAETtAREQFRVVSE 692
Cdd:PRK04863 405 ALDVQQTRAIQYQQAVQALERAKQLCGlpdlTADNAEDWLEEFQAKEQEATEELLSLEQK---LSVAQA-AHSQFEQAYQ 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 693 QLITLRQERAPllkGKSVEDAEAAIRK--KEKQLNDSVEQVRKEGEEVQSRISGMQGEIRQLNssiDELMLRKEQIADPE 770
Cdd:PRK04863 481 LVRKIAGEVSR---SEAWDVARELLRRlrEQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLA---EFCKRLGKNLDDED 554
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 695336968 771 HLPETIARQQATNQETERRLSTVEARLLQQEQNRKKLKQLEQELTEK 817
Cdd:PRK04863 555 ELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAAR 601
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
6-51 |
7.09e-03 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 39.35 E-value: 7.09e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 695336968 6 IRLKNLASIEGTF--EIDFQAEPlrsAGIFAISGPTGAGKSTILDALC 51
Cdd:COG3840 2 LRLDDLTYRYGDFplRFDLTIAA---GERVAILGPSGAGKSTLLNLIA 46
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
889-946 |
8.18e-03 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 36.44 E-value: 8.18e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 695336968 889 RTVYSLSGGE-----SFLISLALALGLSSLSSNNLKVESLFIDEGFGSLDADSLRTVMEALEQ 946
Cdd:pfam13558 28 RRSGGLSGGEkqllaYLPLAAALAAQYGSAEGRPPAPRLVFLDEAFAKLDEENIRTALELLRA 90
|
|
| ABC_SMC5_euk |
cd03277 |
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ... |
3-106 |
8.57e-03 |
|
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213244 [Multi-domain] Cd Length: 213 Bit Score: 38.73 E-value: 8.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695336968 3 ILTIRLKNLASIEgtfEIDFQAEPlrsaGIFAISGPTGAGKSTILDALCLALYDKtPRFsasveslymsdIGESrvnqAD 82
Cdd:cd03277 3 IVRIKLENFVTYD---ETEFRPGP----SLNMIIGPNGSGKSSIVCAICLGLGGK-PKL-----------LGRA----KK 59
|
90 100
....*....|....*....|....
gi 695336968 83 VKNILRRGTGEGFAEVDFLGASGH 106
Cdd:cd03277 60 VGEFVKRGCDEGTIEIELYGNPGN 83
|
|
| GMPK |
cd00071 |
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), ... |
32-65 |
9.32e-03 |
|
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine diphosphate (GDP). It plays an essential role in the biosynthesis of guanosine triphosphate (GTP). This enzyme is also important for the activation of some antiviral and anticancer agents, such as acyclovir, ganciclovir, carbovir, and thiopurines.
Pssm-ID: 238026 Cd Length: 137 Bit Score: 37.51 E-value: 9.32e-03
10 20 30
....*....|....*....|....*....|....
gi 695336968 32 IFAISGPTGAGKSTILDALClALYDKTPRFSASV 65
Cdd:cd00071 1 LIVLSGPSGVGKSTLLKRLL-EEFDPNFGFSVSH 33
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| |
