DNA repair protein RecN [Escherichia coli]
Protein Classification
DNA repair protein RecN( domain architecture ID 11485034)
DNA repair protein RecN may be involved in recombinational repair of damaged DNA
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||||
| PRK10869 | PRK10869 | recombination and repair protein; Provisional |
1-553 | 0e+00 | ||||||||
recombination and repair protein; Provisional : Pssm-ID: 236781 [Multi-domain] Cd Length: 553 Bit Score: 1115.78 E-value: 0e+00
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| Name | Accession | Description | Interval | E-value | |||||||||
| PRK10869 | PRK10869 | recombination and repair protein; Provisional |
1-553 | 0e+00 | |||||||||
recombination and repair protein; Provisional Pssm-ID: 236781 [Multi-domain] Cd Length: 553 Bit Score: 1115.78 E-value: 0e+00
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| RecN | COG0497 | DNA repair ATPase RecN [Replication, recombination and repair]; |
1-553 | 0e+00 | |||||||||
DNA repair ATPase RecN [Replication, recombination and repair]; Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 754.99 E-value: 0e+00
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| recN | TIGR00634 | DNA repair protein RecN; All proteins in this family for which functions are known are ATP ... |
1-553 | 1.86e-173 | |||||||||
DNA repair protein RecN; All proteins in this family for which functions are known are ATP binding proteins involved in the initiation of recombination and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273187 [Multi-domain] Cd Length: 563 Bit Score: 501.96 E-value: 1.86e-173
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| ABC_RecN | cd03241 | ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ... |
2-148 | 3.36e-68 | |||||||||
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins. Pssm-ID: 213208 [Multi-domain] Cd Length: 276 Bit Score: 221.31 E-value: 3.36e-68
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| AAA_23 | pfam13476 | AAA domain; |
5-182 | 1.83e-14 | |||||||||
AAA domain; Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 72.14 E-value: 1.83e-14
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| Name | Accession | Description | Interval | E-value | |||||||||
| PRK10869 | PRK10869 | recombination and repair protein; Provisional |
1-553 | 0e+00 | |||||||||
recombination and repair protein; Provisional Pssm-ID: 236781 [Multi-domain] Cd Length: 553 Bit Score: 1115.78 E-value: 0e+00
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| RecN | COG0497 | DNA repair ATPase RecN [Replication, recombination and repair]; |
1-553 | 0e+00 | |||||||||
DNA repair ATPase RecN [Replication, recombination and repair]; Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 754.99 E-value: 0e+00
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| recN | TIGR00634 | DNA repair protein RecN; All proteins in this family for which functions are known are ATP ... |
1-553 | 1.86e-173 | |||||||||
DNA repair protein RecN; All proteins in this family for which functions are known are ATP binding proteins involved in the initiation of recombination and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273187 [Multi-domain] Cd Length: 563 Bit Score: 501.96 E-value: 1.86e-173
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| ABC_RecN | cd03241 | ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ... |
2-148 | 3.36e-68 | |||||||||
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins. Pssm-ID: 213208 [Multi-domain] Cd Length: 276 Bit Score: 221.31 E-value: 3.36e-68
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| ABC_RecN | cd03241 | ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ... |
390-536 | 1.48e-63 | |||||||||
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins. Pssm-ID: 213208 [Multi-domain] Cd Length: 276 Bit Score: 209.37 E-value: 1.48e-63
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| AAA_23 | pfam13476 | AAA domain; |
5-182 | 1.83e-14 | |||||||||
AAA domain; Pssm-ID: 463890 [Multi-domain] Cd Length: 190 Bit Score: 72.14 E-value: 1.83e-14
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| SbcC | COG0419 | DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
1-73 | 4.40e-09 | |||||||||
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 56.56 E-value: 4.40e-09
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| SMC_N | pfam02463 | RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1-388 | 1.83e-08 | |||||||||
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination. Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.29 E-value: 1.83e-08
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| ABC_Class2 | cd03227 | ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
431-496 | 7.47e-08 | |||||||||
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins. Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 51.98 E-value: 7.47e-08
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| YbjD | COG3593 | Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
2-49 | 2.85e-07 | |||||||||
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair]; Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 52.70 E-value: 2.85e-07
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| recF | PRK00064 | recombination protein F; Reviewed |
2-124 | 3.88e-07 | |||||||||
recombination protein F; Reviewed Pssm-ID: 234608 [Multi-domain] Cd Length: 361 Bit Score: 52.47 E-value: 3.88e-07
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| ABC_Rad50 | cd03240 | ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
5-70 | 5.24e-07 | |||||||||
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence. Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 50.30 E-value: 5.24e-07
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| ABC_RecF | cd03242 | ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that ... |
2-123 | 1.25e-06 | |||||||||
ATP-binding cassette domain of RecF; RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage. When replication is prematurely disrupted by DNA damage, several recF pathway gene products play critical roles processing the arrested replication fork, allowing it to resume and complete its task. This CD represents the nucleotide binding domain of RecF. RecF belongs to a large superfamily of ABC transporters involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases with a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins. Pssm-ID: 213209 [Multi-domain] Cd Length: 270 Bit Score: 49.99 E-value: 1.25e-06
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| ABC_SMC6_euk | cd03276 | ATP-binding cassette domain of eukaryotic SM6 proteins; The structural maintenance of ... |
2-64 | 3.89e-06 | |||||||||
ATP-binding cassette domain of eukaryotic SM6 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18). Pssm-ID: 213243 [Multi-domain] Cd Length: 198 Bit Score: 47.59 E-value: 3.89e-06
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| ABC_Class2 | cd03227 | ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
4-70 | 8.75e-06 | |||||||||
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins. Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 46.20 E-value: 8.75e-06
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| ABC_ATPase | cd00267 | ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
432-496 | 2.14e-05 | |||||||||
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins. Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 44.93 E-value: 2.14e-05
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| PRK01156 | PRK01156 | chromosome segregation protein; Provisional |
1-378 | 2.54e-05 | |||||||||
chromosome segregation protein; Provisional Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.20 E-value: 2.54e-05
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| ABC_sbcCD | cd03279 | ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
4-70 | 6.35e-05 | |||||||||
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini. Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 44.18 E-value: 6.35e-05
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| ABC_SMC_barmotin | cd03278 | ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
415-491 | 7.12e-05 | |||||||||
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18). Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 43.99 E-value: 7.12e-05
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| ABC_SMC_barmotin | cd03278 | ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ... |
2-47 | 1.70e-04 | |||||||||
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18). Pssm-ID: 213245 [Multi-domain] Cd Length: 197 Bit Score: 42.84 E-value: 1.70e-04
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| YhaN | COG4717 | Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2-378 | 2.63e-04 | |||||||||
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 2.63e-04
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| SMC_prok_A | TIGR02169 | chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
17-120 | 2.77e-04 | |||||||||
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins] Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.90 E-value: 2.77e-04
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| COG4637 | COG4637 | Predicted ATPase [General function prediction only]; |
1-77 | 3.56e-04 | |||||||||
Predicted ATPase [General function prediction only]; Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 43.00 E-value: 3.56e-04
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| SMC_prok_B | TIGR02168 | chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2-378 | 5.94e-04 | |||||||||
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins] Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 5.94e-04
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| SMC_prok_A | TIGR02169 | chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
421-491 | 7.54e-04 | |||||||||
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins] Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 7.54e-04
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| ABC_SMC1_euk | cd03275 | ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of ... |
2-116 | 8.72e-04 | |||||||||
ATP-binding cassette domain of eukaryotic SMC1 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18). Pssm-ID: 213242 [Multi-domain] Cd Length: 247 Bit Score: 41.02 E-value: 8.72e-04
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| COG3910 | COG3910 | Predicted ATPase [General function prediction only]; |
9-77 | 1.74e-03 | |||||||||
Predicted ATPase [General function prediction only]; Pssm-ID: 443116 [Multi-domain] Cd Length: 239 Bit Score: 40.13 E-value: 1.74e-03
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| AAA_29 | pfam13555 | P-loop containing region of AAA domain; |
18-42 | 3.04e-03 | |||||||||
P-loop containing region of AAA domain; Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 36.04 E-value: 3.04e-03
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| PRK03918 | PRK03918 | DNA double-strand break repair ATPase Rad50; |
5-73 | 6.84e-03 | |||||||||
DNA double-strand break repair ATPase Rad50; Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 39.28 E-value: 6.84e-03
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| SMC_N | pfam02463 | RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
173-491 | 8.15e-03 | |||||||||
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination. Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 39.18 E-value: 8.15e-03
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| Blast search parameters | ||||
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