|
Name |
Accession |
Description |
Interval |
E-value |
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
20-717 |
3.63e-148 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 449.13 E-value: 3.63e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 20 KPKKINFIYGSNGSGKTTISNLI------GRFNKSDDCVIETKKNSNSSILVYNKKFVEKNFSQSDiGLKGIFTLGENSI 93
Cdd:pfam13166 14 DFKRYNLIYGWNGSGKTTLSRLLrslelgEPHPKFANGKFEWTNGQPLDIRVFNRDFVEENLSEQG-EIKPIFTLGEESI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 94 NLQDNLNELRRKIQVNEENIYIKEKTIRGFEEEIEERTNIIKDKIWNH-QKEISKDFPEAFVGYKNNkQKFLNQCIKVYE 172
Cdd:pfam13166 93 EIQEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKiKRKKNSALSEALNGFKYE-ANFKSRLLREIE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 173 ENILEKSEEIltnSLEKLKENYNISFSDDIKLYEVFNVNDTEkILEIEKTNLIEKVIVGGNdSLIGQFIQSLKNSDWVKQ 252
Cdd:pfam13166 172 KDNFNAGVLL---SDEDRKAALATVFSDNKPEIAPLTFNVID-FDALEKAEILIQKVIGKS-SAIEELIKNPDLADWVEQ 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 253 GLDYLDYSNHTCPFCNQSISEKLEQEIKDYFNEEYEQDLKKIKEIKQVY----SSCFEKIESNMLFILRKSIPYLNTKLL 328
Cdd:pfam13166 247 GLELHKAHLDTCPFCGQPLPAERKAALEAHFDDEFTEFQNRLQKLIEKVesaiSSLLAQLPAVSDLASLLSAFELDVEDI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 329 SKEFEVLEKQYEVNQKQLKEKLRNPSQKLKIKSLVPKIENINEIISSLNESIETNNNIIRNKEREQNKFKKNLWIYIVNN 408
Cdd:pfam13166 327 ESEAEVLNSQLDGLRRALEAKRKDPFKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAKKKLRLHLVEE 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 409 MKQDLKEYVNFKNGKFKAIANIRRQISGLKNENKKTNKEIGEIETNITSVEPTVKNINEILNKFDFKGFKLQENSNTKGt 488
Cdd:pfam13166 407 FKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKLLKAFGFGELELSFNEEGKG- 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 489 YLIVREDGSNANETMSEGEYNFITFLYFYYLVYGSheSTSLTSNKIVIIDDPISSLDSNVLFIVSTLVKNLIndcrnNKN 568
Cdd:pfam13166 486 YRIIRKGGSQAAETLSEGERTAIAFLYFLKSLKDS--DNDIGKDKIVVIDDPVSSLDSNHLFIVFSLIRTRT-----EKT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 569 GIQQIFNLTHNIYFHKEITFLGSRERFSPNEVMYgIIRKKDNISYFNTYE--NNPIESSYQLMWKELNSEEMSPITSF-- 644
Cdd:pfam13166 559 NAKQVFILTHNFYFFKEVTNWFDNKRKKKNERFY-ILKKDGNSSKIKEYDrlLNPIESEYHYLFKEVYRASENDDHFYgm 637
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 686405777 645 -NTMRRILEYYFNIIGGMDYEKCI-NKFDGIDKILCKSLISGINDGSHFISDDFVITFDEASMRNYKRVFKLVFE 717
Cdd:pfam13166 638 pNVARRILETFFKFPGGVGRDKDIsEFFEGEDKAVCASLLRLLNTGSHSDNDDLDTDSDPSLLEEIAAVFRKIFK 712
|
|
| RloC |
COG4694 |
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis]; |
1-720 |
1.68e-128 |
|
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 443729 [Multi-domain] Cd Length: 692 Bit Score: 397.57 E-value: 1.68e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 1 MIKKI-SLQNIATYRNYVEI-KPKKINFIYGSNGSGKTTISNLI-----GRFNKSDDCVIETKKNSNS---SILVYNKKF 70
Cdd:COG4694 1 MITKIkKLKNVGAFKDFGWLaFFKKLNLIYGENGSGKSTLSRILrslelGDTSSEVIAEFEIEAGGSApnpSVRVFNRDF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 71 VEKNFSQsDIGLKGIFTLGENSINLQDNLNELRRKIQVNEENIYIKEKTIRGFEEEIEERTNIIKDKIWNHQKEISkdfp 150
Cdd:COG4694 81 VEENLRS-GEEIKGIFTLGEENIELEEEIEELEKEIEDLKKELDKLEKELKEAKKALEKLLEDLAKSIKDDLKKLF---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 151 eAFVGYKNNKQKFLNQCIKVYEENILEKSEEILTNSLEKLKENYNISFSDDIKLyevfnvndtekiLEIEKTNLIEKVIV 230
Cdd:COG4694 156 -ASSGRNYRKANLEKKLSALKSSSEDELKEKLKLLKEEEPEPIAPITPLPDLKA------------LLSEAETLLEKSAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 231 GGNDSLIGQFIQSLKNSDWVKQGLDYLDYSNH-TCPFCNQSISEKLEQEIKDYFNEEYEQDLKKIKEIKQVYSSCFEKIE 309
Cdd:COG4694 223 SSAIEELAALIQNPGNSDWVEQGLAYHKEEEDdTCPFCQQELAAERIEALEAYFDDEYEKLLAALKDLLEELESAINALS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 310 SNMLFILRKSIPYLNTKLlSKEFEVLEKQYEVNQKQLKEKLRNPSQKLKIkSLVPKIENINEIISSLNESIETNNNIIRN 389
Cdd:COG4694 303 ALLLEILRTLLPSAKEDL-KAALEALNALLETLLAALEEKIANPSTSIDL-DDQELLDELNDLIAALNALIEEHNAKIAN 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 390 KEREQNKFKKNLWIYIVNNMKQDLKEYVNfkngKFKAIANIRRQISGLKNENKKTNKEIGEIETNITSVEPTVKNINEIL 469
Cdd:COG4694 381 LKAEKEEARKKLEAHELAELKEDLSRYKA----EVEELIEELKTIKALKKALEDLKTEISELEAELSSVDEAADEINEEL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 470 NKFDFKGFKLQENSNTKGTYLIVR--EDGSNANETMSEGEYNFITFLYFYYLVygsHESTSLTSNKIVIIDDPISSLDSN 547
Cdd:COG4694 457 KALGFDEFSLEAVEDGRSSYRLKRngENDAKPAKTLSEGEKTAIALAYFLAEL---EGDENDLKKKIVVIDDPVSSLDSN 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 548 VLFIVSTLVKNLINDCRnnkngiqQIFNLTHNIYFHKEITFLGSRERFSPNEVMYgIIRKKDNISYFNTYEN-NPIESSY 626
Cdd:COG4694 534 HRFAVASLLKELSKKAK-------QVIVLTHNLYFLKELRDLADEDNKKKNCAFY-EIRKDNRGSKIIKLDLlNPYESEY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 627 QLMWKEL---NSEEMSPITSFNTMRRILEYYFNIiggmDYEKCINKFDGIDKILCKSLISGINDGSHFISDDFVITFDea 703
Cdd:COG4694 606 HYLFKEVydfAEGGDSLYLIPNAMRRILEAYLRF----KYPDKLDELLEDDEEEKKSLYRYINRFSHGDNSTDSLLEE-- 679
|
730
....*....|....*..
gi 686405777 704 smrnYKRVFKLVFEKLG 720
Cdd:COG4694 680 ----YKSVFRRIFEFIK 692
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
94-486 |
9.30e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 9.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 94 NLQDNLNELRRKIQVNEENIY----IKEK-----TIRGFEEEIEERTNIIKDKIWNHQKEISKdfPEAFVGYKNNKQKFL 164
Cdd:PRK03918 263 ELEERIEELKKEIEELEEKVKelkeLKEKaeeyiKLSEFYEEYLDELREIEKRLSRLEEEING--IEERIKELEEKEERL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 165 NQCIKVYEE-----NILEKSEEILTNSLEKLKENYNISfsDDIKLYEVFNVNDTEKILEIEKTNLIEKVivggndSLIGQ 239
Cdd:PRK03918 341 EELKKKLKElekrlEELEERHELYEEAKAKKEELERLK--KRLTGLTPEKLEKELEELEKAKEEIEEEI------SKITA 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 240 FIQSLKN-SDWVKQGLDYLDYSNHTCPFCNQSISEKLEQEIKDYFNEEY---EQDLKKIKEIKQVYSSCFEKIEsNMLFI 315
Cdd:PRK03918 413 RIGELKKeIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELkriEKELKEIEEKERKLRKELRELE-KVLKK 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 316 LRKSIPYLNTKLLSKEFEvlEKQYEVNQKQLK------EKLRNPSQKLK--IKSLVPKIENINEIISSLNESIETnnniI 387
Cdd:PRK03918 492 ESELIKLKELAEQLKELE--EKLKKYNLEELEkkaeeyEKLKEKLIKLKgeIKSLKKELEKLEELKKKLAELEKK----L 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 388 RNKEREQNKFKK---NLWIYIVNNMKQDLKEYVNFKNgKFKAIANIRRQISGLKNENKKTNKEIGEIETNI----TSVEP 460
Cdd:PRK03918 566 DELEEELAELLKeleELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELaeteKRLEE 644
|
410 420
....*....|....*....|....*.
gi 686405777 461 TVKNINEILNKFDFKGFKLQENSNTK 486
Cdd:PRK03918 645 LRKELEELEKKYSEEEYEELREEYLE 670
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
2-51 |
3.40e-04 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 43.02 E-value: 3.40e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 686405777 2 IKKISLQNIATYRNYVEIKP--KKINFIYGSNGSGKTTISNLIgRFNKSDDC 51
Cdd:cd03272 1 IKQVIIQGFKSYKDQTVIEPfsPKHNVVVGRNGSGKSNFFAAI-RFVLSDEY 51
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
90-437 |
4.64e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.43 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 90 ENSINLQDNLNELRRKIqvneENIYIK-EKTIRgFEEeieertniIKDKIWNHQKEISKDFPEAFvgykNNKQKFLNQCI 168
Cdd:TIGR02168 186 ENLDRLEDILNELERQL----KSLERQaEKAER-YKE--------LKAELRELELALLVLRLEEL----REELEELQEEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 169 KVYEENILEKSEEIlTNSLEKLKENynisfsddiklyEVFNVNDTEKILEIEKTNLIEKVIVGGNDSLIGQFIQSLKNSD 248
Cdd:TIGR02168 249 KEAEEELEELTAEL-QELEEKLEEL------------RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 249 WVKQGLDYLDYSNHTCPFCNQSISEKLEQEI------KDYFNEEYEQDLKKIKEIKQVYSSCFEKIE--SNMLFILRKSI 320
Cdd:TIGR02168 316 RQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLEtlRSKVAQLELQI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 321 pylntKLLSKEFEVLEKQYE---VNQKQLKEKLRNPSQKLKIKSLVPKIENINEIISSLNESIETNNNIIRNKEREQNKF 397
Cdd:TIGR02168 396 -----ASLNNEIERLEARLErleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 686405777 398 KKNlwiyivNNMKQDLKEYVNFKNGKFKAIANIRRQISGL 437
Cdd:TIGR02168 471 EEA------EQALDAAERELAQLQARLDSLERLQENLEGF 504
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
20-717 |
3.63e-148 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 449.13 E-value: 3.63e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 20 KPKKINFIYGSNGSGKTTISNLI------GRFNKSDDCVIETKKNSNSSILVYNKKFVEKNFSQSDiGLKGIFTLGENSI 93
Cdd:pfam13166 14 DFKRYNLIYGWNGSGKTTLSRLLrslelgEPHPKFANGKFEWTNGQPLDIRVFNRDFVEENLSEQG-EIKPIFTLGEESI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 94 NLQDNLNELRRKIQVNEENIYIKEKTIRGFEEEIEERTNIIKDKIWNH-QKEISKDFPEAFVGYKNNkQKFLNQCIKVYE 172
Cdd:pfam13166 93 EIQEKIAKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKiKRKKNSALSEALNGFKYE-ANFKSRLLREIE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 173 ENILEKSEEIltnSLEKLKENYNISFSDDIKLYEVFNVNDTEkILEIEKTNLIEKVIVGGNdSLIGQFIQSLKNSDWVKQ 252
Cdd:pfam13166 172 KDNFNAGVLL---SDEDRKAALATVFSDNKPEIAPLTFNVID-FDALEKAEILIQKVIGKS-SAIEELIKNPDLADWVEQ 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 253 GLDYLDYSNHTCPFCNQSISEKLEQEIKDYFNEEYEQDLKKIKEIKQVY----SSCFEKIESNMLFILRKSIPYLNTKLL 328
Cdd:pfam13166 247 GLELHKAHLDTCPFCGQPLPAERKAALEAHFDDEFTEFQNRLQKLIEKVesaiSSLLAQLPAVSDLASLLSAFELDVEDI 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 329 SKEFEVLEKQYEVNQKQLKEKLRNPSQKLKIKSLVPKIENINEIISSLNESIETNNNIIRNKEREQNKFKKNLWIYIVNN 408
Cdd:pfam13166 327 ESEAEVLNSQLDGLRRALEAKRKDPFKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAKKKLRLHLVEE 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 409 MKQDLKEYVNFKNGKFKAIANIRRQISGLKNENKKTNKEIGEIETNITSVEPTVKNINEILNKFDFKGFKLQENSNTKGt 488
Cdd:pfam13166 407 FKSEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKLLKAFGFGELELSFNEEGKG- 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 489 YLIVREDGSNANETMSEGEYNFITFLYFYYLVYGSheSTSLTSNKIVIIDDPISSLDSNVLFIVSTLVKNLIndcrnNKN 568
Cdd:pfam13166 486 YRIIRKGGSQAAETLSEGERTAIAFLYFLKSLKDS--DNDIGKDKIVVIDDPVSSLDSNHLFIVFSLIRTRT-----EKT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 569 GIQQIFNLTHNIYFHKEITFLGSRERFSPNEVMYgIIRKKDNISYFNTYE--NNPIESSYQLMWKELNSEEMSPITSF-- 644
Cdd:pfam13166 559 NAKQVFILTHNFYFFKEVTNWFDNKRKKKNERFY-ILKKDGNSSKIKEYDrlLNPIESEYHYLFKEVYRASENDDHFYgm 637
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 686405777 645 -NTMRRILEYYFNIIGGMDYEKCI-NKFDGIDKILCKSLISGINDGSHFISDDFVITFDEASMRNYKRVFKLVFE 717
Cdd:pfam13166 638 pNVARRILETFFKFPGGVGRDKDIsEFFEGEDKAVCASLLRLLNTGSHSDNDDLDTDSDPSLLEEIAAVFRKIFK 712
|
|
| RloC |
COG4694 |
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis]; |
1-720 |
1.68e-128 |
|
Wobble nucleotide-excising tRNase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 443729 [Multi-domain] Cd Length: 692 Bit Score: 397.57 E-value: 1.68e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 1 MIKKI-SLQNIATYRNYVEI-KPKKINFIYGSNGSGKTTISNLI-----GRFNKSDDCVIETKKNSNS---SILVYNKKF 70
Cdd:COG4694 1 MITKIkKLKNVGAFKDFGWLaFFKKLNLIYGENGSGKSTLSRILrslelGDTSSEVIAEFEIEAGGSApnpSVRVFNRDF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 71 VEKNFSQsDIGLKGIFTLGENSINLQDNLNELRRKIQVNEENIYIKEKTIRGFEEEIEERTNIIKDKIWNHQKEISkdfp 150
Cdd:COG4694 81 VEENLRS-GEEIKGIFTLGEENIELEEEIEELEKEIEDLKKELDKLEKELKEAKKALEKLLEDLAKSIKDDLKKLF---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 151 eAFVGYKNNKQKFLNQCIKVYEENILEKSEEILTNSLEKLKENYNISFSDDIKLyevfnvndtekiLEIEKTNLIEKVIV 230
Cdd:COG4694 156 -ASSGRNYRKANLEKKLSALKSSSEDELKEKLKLLKEEEPEPIAPITPLPDLKA------------LLSEAETLLEKSAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 231 GGNDSLIGQFIQSLKNSDWVKQGLDYLDYSNH-TCPFCNQSISEKLEQEIKDYFNEEYEQDLKKIKEIKQVYSSCFEKIE 309
Cdd:COG4694 223 SSAIEELAALIQNPGNSDWVEQGLAYHKEEEDdTCPFCQQELAAERIEALEAYFDDEYEKLLAALKDLLEELESAINALS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 310 SNMLFILRKSIPYLNTKLlSKEFEVLEKQYEVNQKQLKEKLRNPSQKLKIkSLVPKIENINEIISSLNESIETNNNIIRN 389
Cdd:COG4694 303 ALLLEILRTLLPSAKEDL-KAALEALNALLETLLAALEEKIANPSTSIDL-DDQELLDELNDLIAALNALIEEHNAKIAN 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 390 KEREQNKFKKNLWIYIVNNMKQDLKEYVNfkngKFKAIANIRRQISGLKNENKKTNKEIGEIETNITSVEPTVKNINEIL 469
Cdd:COG4694 381 LKAEKEEARKKLEAHELAELKEDLSRYKA----EVEELIEELKTIKALKKALEDLKTEISELEAELSSVDEAADEINEEL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 470 NKFDFKGFKLQENSNTKGTYLIVR--EDGSNANETMSEGEYNFITFLYFYYLVygsHESTSLTSNKIVIIDDPISSLDSN 547
Cdd:COG4694 457 KALGFDEFSLEAVEDGRSSYRLKRngENDAKPAKTLSEGEKTAIALAYFLAEL---EGDENDLKKKIVVIDDPVSSLDSN 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 548 VLFIVSTLVKNLINDCRnnkngiqQIFNLTHNIYFHKEITFLGSRERFSPNEVMYgIIRKKDNISYFNTYEN-NPIESSY 626
Cdd:COG4694 534 HRFAVASLLKELSKKAK-------QVIVLTHNLYFLKELRDLADEDNKKKNCAFY-EIRKDNRGSKIIKLDLlNPYESEY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 627 QLMWKEL---NSEEMSPITSFNTMRRILEYYFNIiggmDYEKCINKFDGIDKILCKSLISGINDGSHFISDDFVITFDea 703
Cdd:COG4694 606 HYLFKEVydfAEGGDSLYLIPNAMRRILEAYLRF----KYPDKLDELLEDDEEEKKSLYRYINRFSHGDNSTDSLLEE-- 679
|
730
....*....|....*..
gi 686405777 704 smrnYKRVFKLVFEKLG 720
Cdd:COG4694 680 ----YKSVFRRIFEFIK 692
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
94-486 |
9.30e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 9.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 94 NLQDNLNELRRKIQVNEENIY----IKEK-----TIRGFEEEIEERTNIIKDKIWNHQKEISKdfPEAFVGYKNNKQKFL 164
Cdd:PRK03918 263 ELEERIEELKKEIEELEEKVKelkeLKEKaeeyiKLSEFYEEYLDELREIEKRLSRLEEEING--IEERIKELEEKEERL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 165 NQCIKVYEE-----NILEKSEEILTNSLEKLKENYNISfsDDIKLYEVFNVNDTEKILEIEKTNLIEKVivggndSLIGQ 239
Cdd:PRK03918 341 EELKKKLKElekrlEELEERHELYEEAKAKKEELERLK--KRLTGLTPEKLEKELEELEKAKEEIEEEI------SKITA 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 240 FIQSLKN-SDWVKQGLDYLDYSNHTCPFCNQSISEKLEQEIKDYFNEEY---EQDLKKIKEIKQVYSSCFEKIEsNMLFI 315
Cdd:PRK03918 413 RIGELKKeIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELkriEKELKEIEEKERKLRKELRELE-KVLKK 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 316 LRKSIPYLNTKLLSKEFEvlEKQYEVNQKQLK------EKLRNPSQKLK--IKSLVPKIENINEIISSLNESIETnnniI 387
Cdd:PRK03918 492 ESELIKLKELAEQLKELE--EKLKKYNLEELEkkaeeyEKLKEKLIKLKgeIKSLKKELEKLEELKKKLAELEKK----L 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 388 RNKEREQNKFKK---NLWIYIVNNMKQDLKEYVNFKNgKFKAIANIRRQISGLKNENKKTNKEIGEIETNI----TSVEP 460
Cdd:PRK03918 566 DELEEELAELLKeleELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELaeteKRLEE 644
|
410 420
....*....|....*....|....*.
gi 686405777 461 TVKNINEILNKFDFKGFKLQENSNTK 486
Cdd:PRK03918 645 LRKELEELEKKYSEEEYEELREEYLE 670
|
|
| RecF |
COG1195 |
Recombinational DNA repair ATPase RecF [Replication, recombination and repair]; |
2-38 |
1.30e-05 |
|
Recombinational DNA repair ATPase RecF [Replication, recombination and repair];
Pssm-ID: 440808 [Multi-domain] Cd Length: 352 Bit Score: 47.84 E-value: 1.30e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 686405777 2 IKKISLQNiatYRNY--VEIKP-KKINFIYGSNGSGKTTI 38
Cdd:COG1195 2 LKRLSLTN---FRNYesLELEFsPGINVLVGPNGQGKTNL 38
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
1-38 |
6.70e-05 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 44.62 E-value: 6.70e-05
10 20 30
....*....|....*....|....*....|....*....
gi 686405777 1 MIKKISLQNIATYRNYVEIK-PKKINFIYGSNGSGKTTI 38
Cdd:COG0419 1 KLLRLRLENFRSYRDTETIDfDDGLNLIVGPNGAGKSTI 39
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
1-42 |
1.15e-04 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 44.92 E-value: 1.15e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 686405777 1 MIKKISLQNiatYRNY--VEIKPKKINFIYGSNGSGKttiSNLI 42
Cdd:COG4637 1 MITRIRIKN---FKSLrdLELPLGPLTVLIGANGSGK---SNLL 38
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
2-51 |
3.40e-04 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 43.02 E-value: 3.40e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 686405777 2 IKKISLQNIATYRNYVEIKP--KKINFIYGSNGSGKTTISNLIgRFNKSDDC 51
Cdd:cd03272 1 IKQVIIQGFKSYKDQTVIEPfsPKHNVVVGRNGSGKSNFFAAI-RFVLSDEY 51
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
1-129 |
8.96e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 41.91 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 1 MIKKISLQNIATYRNyVEI---KPKKINFIYGSNGSGKTTI--------SNLIGRFNKSDD---CVIETKKNSNSSILVY 66
Cdd:COG3950 2 RIKSLTIENFRGFED-LEIdfdNPPRLTVLVGENGSGKTTLleaialalSGLLSRLDDVKFrklLIRNGEFGDSAKLILY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 686405777 67 --------------NKKFVEKNFSQSDiGLKGIFtlgENSINLQDNLNELRRKI-QVNEENIYIKEKTIRGFEEEIEE 129
Cdd:COG3950 81 ygtsrllldgplkkLERLKEEYFSRLD-GYDSLL---DEDSNLREFLEWLREYLeDLENKLSDELDEKLEAVREALNK 154
|
|
| recF |
PRK00064 |
recombination protein F; Reviewed |
2-38 |
3.09e-03 |
|
recombination protein F; Reviewed
Pssm-ID: 234608 [Multi-domain] Cd Length: 361 Bit Score: 40.53 E-value: 3.09e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 686405777 2 IKKISLQNiatYRNY--VEIKP-KKINFIYGSNGSGKTTI 38
Cdd:PRK00064 3 LTRLSLTD---FRNYeeLDLELsPGVNVLVGENGQGKTNL 39
|
|
| ABC_SMC5_euk |
cd03277 |
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ... |
2-68 |
3.28e-03 |
|
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213244 [Multi-domain] Cd Length: 213 Bit Score: 39.50 E-value: 3.28e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 686405777 2 IKKISLQNIATYrNYVEIKP-KKINFIYGSNGSGKTTI-----------SNLIGRFNKSDDCVIETKKNSNSSILVYNK 68
Cdd:cd03277 3 IVRIKLENFVTY-DETEFRPgPSLNMIIGPNGSGKSSIvcaiclglggkPKLLGRAKKVGEFVKRGCDEGTIEIELYGN 80
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
18-45 |
3.31e-03 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 38.90 E-value: 3.31e-03
10 20
....*....|....*....|....*...
gi 686405777 18 EIKPKKINFIYGSNGSGKTTISNLIGRF 45
Cdd:cd03228 24 TIKPGEKVAIVGPSGSGKSTLLKLLLRL 51
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
90-437 |
4.64e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.43 E-value: 4.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 90 ENSINLQDNLNELRRKIqvneENIYIK-EKTIRgFEEeieertniIKDKIWNHQKEISKDFPEAFvgykNNKQKFLNQCI 168
Cdd:TIGR02168 186 ENLDRLEDILNELERQL----KSLERQaEKAER-YKE--------LKAELRELELALLVLRLEEL----REELEELQEEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 169 KVYEENILEKSEEIlTNSLEKLKENynisfsddiklyEVFNVNDTEKILEIEKTNLIEKVIVGGNDSLIGQFIQSLKNSD 248
Cdd:TIGR02168 249 KEAEEELEELTAEL-QELEEKLEEL------------RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 249 WVKQGLDYLDYSNHTCPFCNQSISEKLEQEI------KDYFNEEYEQDLKKIKEIKQVYSSCFEKIE--SNMLFILRKSI 320
Cdd:TIGR02168 316 RQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLEtlRSKVAQLELQI 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 321 pylntKLLSKEFEVLEKQYE---VNQKQLKEKLRNPSQKLKIKSLVPKIENINEIISSLNESIETNNNIIRNKEREQNKF 397
Cdd:TIGR02168 396 -----ASLNNEIERLEARLErleDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 686405777 398 KKNlwiyivNNMKQDLKEYVNFKNGKFKAIANIRRQISGL 437
Cdd:TIGR02168 471 EEA------EQALDAAERELAQLQARLDSLERLQENLEGF 504
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
285-484 |
4.75e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.39 E-value: 4.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 285 EEYEQDLKKIKEIKQVYSSCFEKIESNMLFILRKSIPYLN-TKLLSKEFEVLEKQYEVNQKQLKE-KLRNPSQKLKIKSL 362
Cdd:TIGR04523 366 EEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKlNQQKDEQIKKLQQEKELLEKEIERlKETIIKNNSEIKDL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 363 VPKIENINEIISSLNESIETNNNIIRNKEREQNKFKKNLWIyIVNNMKQDLKEYVNFKNGKF---KAIANIRRQISGLKN 439
Cdd:TIGR04523 446 TNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ-KQKELKSKEKELKKLNEEKKeleEKVKDLTKKISSLKE 524
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 686405777 440 ENKKTNKEIGEIETNITSVEPTVKNINEILNKFDFKGFKLQENSN 484
Cdd:TIGR04523 525 KIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKE 569
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
276-399 |
6.46e-03 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 40.21 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 276 EQEIKDYFNEEYEQDLKKIKEIKQVYSSCFEKIESNML-----------FILRKSIPYLNTKLLSKEFEVLEKQYEVNQK 344
Cdd:PRK00448 89 EELLLDYWNEIIEKAKKNSPLFKSLLKKQKVEVEGNKLiikvnneierdHLKKKHLPKLIKQYEKFGFGILKIDFEIDDS 168
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 686405777 345 -----QLKEKLRNPSQKLKIKSLVPKIENINEIISSLNESIETNNNIIRNKEREQNKFKK 399
Cdd:PRK00448 169 keeleKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDPKEGPVQIGKKIDKEEITP 228
|
|
| COG1106 |
COG1106 |
ATPase/GTPase, AAA15 family [General function prediction only]; |
1-38 |
7.38e-03 |
|
ATPase/GTPase, AAA15 family [General function prediction only];
Pssm-ID: 440723 [Multi-domain] Cd Length: 330 Bit Score: 39.26 E-value: 7.38e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 686405777 1 MIKKISLQNIATYRNYVEI-------KPKKINFIYGSNGSGKTTI 38
Cdd:COG1106 1 MLISFSIENFRSFKDELTLsmvasglRLLRVNLIYGANASGKSNL 45
|
|
|