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Conserved domains on  [gi|657908800|ref|WP_029611067|]
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AAA family ATPase [Pseudomonas aeruginosa]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10246 super family cl32485
exonuclease subunit SbcC; Provisional
1-1199 2.43e-99

exonuclease subunit SbcC; Provisional


The actual alignment was detected with superfamily member PRK10246:

Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 340.62  E-value: 2.43e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:PRK10246    1 MKILSLRLKNLNSLKGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQS------------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 dERNLLRRGCASGYAEVDFvGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLDTQQMLaANKKSEFREQLEQKLGLNF 160
Cdd:PRK10246   68 -QNDLMTRDTAECLAEVEF-EVKGEAYRAFWSQNRARNQPDGNLQAPRVELARCADGKIL-ADKVKDKLELTATLTGLDY 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:PRK10246  145 GRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTAS 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:PRK10246  225 LQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRPHWERIQEQSA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  321 ELRHSEqqqrqrteqqaagaERLQGLQARVQEARERQAqaddhlRQAQAPLREAFQLESEARRLERTLAERqelhrqsnq 400
Cdd:PRK10246  305 ALAHTR--------------QQIEEVNTRLQSTMALRA------RIRHHAAKQSAELQAQQQSLNTWLAEH--------- 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  401 rhaqqsDAARQLDMEQQRHVAEQAQLQaalRDSQALAALgdawathQGQLAAFVQRRqralesqAQLPELEKSLAqagep 480
Cdd:PRK10246  356 ------DRFRQWNNELAGWRAQFSQQT---SDREQLRQW-------QQQLTHAEQKL-------NALPAITLTLT----- 407
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  481 lerlqaqwaalhgsePDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQAlLDLKRQgsq 560
Cdd:PRK10246  408 ---------------ADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA-LNEMRQ--- 468
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  561 caeQVKAAEQALQVTRELLQRQrlARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLaalgEHDDQEQVRAeqALER 640
Cdd:PRK10246  469 ---RYKEKTQQLADVKTICEQE--ARIKDLEAQRAQLQAGQPCPLCGSTSHPAVEAYQAL----EPGVNQSRLD--ALEK 537
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  641 LRQTLvglregyssqrerlnqsRQEQQELTGQLAALDRQLEQWTlPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFD 720
Cdd:PRK10246  538 EVKKL-----------------GEEGAALRGQLDALTKQLQRDE-SEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQ 599
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  721 RLIARQrqtqqlqqelraaetilQQRQQALTEQRQRYEhLQQQVEEDSQQLRPLlsDEHWQRWQADPLRTFQALGESieq 800
Cdd:PRK10246  600 PWLDAQ-----------------EEHERQLRLLSQRHE-LQGQIAAHNQQIIQY--QQQIEQRQQQLLTALAGYALT--- 656
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  801 rrqqqarlqqveqrlqeLKQRCDESSWQlkqsDEQRNEARQAEERvQAELAELNGRLGAhlgqhacaqdWQLSLEHAAQA 880
Cdd:PRK10246  657 -----------------LPQEDEEASWL----ATRQQEAQSWQQR-QNELTALQNRIQQ----------LTPLLETLPQS 704
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  881 AQSAVETLQAPLDSLRE---EQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLgLSEEQATQWR 957
Cdd:PRK10246  705 DDLPHSEETVALDNWRQvheQCLSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAAL-LDEETLTQLE 783
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  958 EQLQRLQEEITRQQTLEAERQAQLLQHRRQRPE-----TDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQ 1032
Cdd:PRK10246  784 QLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDgldltVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQ 863
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1033 ALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSE-LGLLVVDTEMGDE 1111
Cdd:PRK10246  864 ALMQQIAQATQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVWLANQQLTRLHGRYLLQRKASEaLELEVVDTWQADA 943
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1112 LRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:PRK10246  944 VRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERI 1023

                  ....*...
gi 657908800 1192 PVQVRVQR 1199
Cdd:PRK10246 1024 PVQIKVKK 1031
 
Name Accession Description Interval E-value
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
1-1199 2.43e-99

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 340.62  E-value: 2.43e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:PRK10246    1 MKILSLRLKNLNSLKGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQS------------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 dERNLLRRGCASGYAEVDFvGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLDTQQMLaANKKSEFREQLEQKLGLNF 160
Cdd:PRK10246   68 -QNDLMTRDTAECLAEVEF-EVKGEAYRAFWSQNRARNQPDGNLQAPRVELARCADGKIL-ADKVKDKLELTATLTGLDY 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:PRK10246  145 GRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTAS 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:PRK10246  225 LQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRPHWERIQEQSA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  321 ELRHSEqqqrqrteqqaagaERLQGLQARVQEARERQAqaddhlRQAQAPLREAFQLESEARRLERTLAERqelhrqsnq 400
Cdd:PRK10246  305 ALAHTR--------------QQIEEVNTRLQSTMALRA------RIRHHAAKQSAELQAQQQSLNTWLAEH--------- 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  401 rhaqqsDAARQLDMEQQRHVAEQAQLQaalRDSQALAALgdawathQGQLAAFVQRRqralesqAQLPELEKSLAqagep 480
Cdd:PRK10246  356 ------DRFRQWNNELAGWRAQFSQQT---SDREQLRQW-------QQQLTHAEQKL-------NALPAITLTLT----- 407
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  481 lerlqaqwaalhgsePDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQAlLDLKRQgsq 560
Cdd:PRK10246  408 ---------------ADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA-LNEMRQ--- 468
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  561 caeQVKAAEQALQVTRELLQRQrlARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLaalgEHDDQEQVRAeqALER 640
Cdd:PRK10246  469 ---RYKEKTQQLADVKTICEQE--ARIKDLEAQRAQLQAGQPCPLCGSTSHPAVEAYQAL----EPGVNQSRLD--ALEK 537
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  641 LRQTLvglregyssqrerlnqsRQEQQELTGQLAALDRQLEQWTlPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFD 720
Cdd:PRK10246  538 EVKKL-----------------GEEGAALRGQLDALTKQLQRDE-SEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQ 599
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  721 RLIARQrqtqqlqqelraaetilQQRQQALTEQRQRYEhLQQQVEEDSQQLRPLlsDEHWQRWQADPLRTFQALGESieq 800
Cdd:PRK10246  600 PWLDAQ-----------------EEHERQLRLLSQRHE-LQGQIAAHNQQIIQY--QQQIEQRQQQLLTALAGYALT--- 656
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  801 rrqqqarlqqveqrlqeLKQRCDESSWQlkqsDEQRNEARQAEERvQAELAELNGRLGAhlgqhacaqdWQLSLEHAAQA 880
Cdd:PRK10246  657 -----------------LPQEDEEASWL----ATRQQEAQSWQQR-QNELTALQNRIQQ----------LTPLLETLPQS 704
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  881 AQSAVETLQAPLDSLRE---EQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLgLSEEQATQWR 957
Cdd:PRK10246  705 DDLPHSEETVALDNWRQvheQCLSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAAL-LDEETLTQLE 783
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  958 EQLQRLQEEITRQQTLEAERQAQLLQHRRQRPE-----TDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQ 1032
Cdd:PRK10246  784 QLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDgldltVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQ 863
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1033 ALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSE-LGLLVVDTEMGDE 1111
Cdd:PRK10246  864 ALMQQIAQATQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVWLANQQLTRLHGRYLLQRKASEaLELEVVDTWQADA 943
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1112 LRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:PRK10246  944 VRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERI 1023

                  ....*...
gi 657908800 1192 PVQVRVQR 1199
Cdd:PRK10246 1024 PVQIKVKK 1031
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
1-1203 1.25e-57

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 217.53  E-value: 1.25e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     1 MKILAIRLKNLASLAGEQEIDFTREPlssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:TIGR00618    1 MKPLRLTLKNFGSYKGTHTIDFTALG----PIFLICGKTGAGKTTLLDAITYALYGKLPRRSEVIRS------------- 63
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    81 dERNLLRRGCASGYAEVDFVgIDGHRYRARWETRRSRDKADGALQKSQQSLQDlDTQQMLAANKKSEFREQLEQKLGLNF 160
Cdd:TIGR00618   64 -LNSLYAAPSEAAFAELEFS-LGTKIYRVHRTLRCTRSHRKTEQPEQLYLEQK-KGRGRILAAKKSETEEVIHDLLKLDY 140
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:TIGR00618  141 KTFTRVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER 220
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQscehaqgqlaearqawdalaterETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQE-----------------------EQLKKQQLLKQLRARIEELRAQEA 277
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   321 ELrhseqqqrqrteqqaagaerlqglqARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQ 400
Cdd:TIGR00618  278 VL-------------------------EETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   401 RHAQQSDAARQLDMEQQRHVAEQAQLQAAlrDSQALaalgdaWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEP 480
Cdd:TIGR00618  333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAH--EVATS------IREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDI 404
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   481 LERLQAQWAALHGSEPDdlaarldelrrqtdslERQQALHKEWQQALDQRtglarRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:TIGR00618  405 LQREQATIDTRTSAFRD----------------LQGQLAHAKKQQELQQR-----YAELCAAAITCTAQCEKLEKIHLQE 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   561 CAEQVKAAEQALQVTRELLQRQrlARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLL-----AALGEHDDQEQVRAE 635
Cdd:TIGR00618  464 SAQSLKEREQQLQTKEQIHLQE--TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDnpgplTRRMQRGEQTYAQLE 541
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   636 QALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQC 715
Cdd:TIGR00618  542 TSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKL 621
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   716 QRDFDRLiarqrqtqqlqQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPlrtfQALG 795
Cdd:TIGR00618  622 QPEQDLQ-----------DVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL----QKMQ 686
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   796 ESIEQRRQQQARLQQVEQRLQELKQRcdesswqLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSle 875
Cdd:TIGR00618  687 SEKEQLTYWKEMLAQCQTLLRELETH-------IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLK-- 757
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   876 haAQAAQSAVETLQAPLDSLREEQLrlaealehlqqqrqrqqdefqrlqadwqawrerqdnlddsrldallglseEQATQ 955
Cdd:TIGR00618  758 --ARTEAHFNNNEEVTAALQTGAEL--------------------------------------------------SHLAA 785
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   956 WREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALL 1035
Cdd:TIGR00618  786 EIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLT 865
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  1036 AELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQR---GGSELGLLVVDTEMGDEL 1112
Cdd:TIGR00618  866 QEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGRFHGRYADSHvnaRKYQGLALLVADAYTGSV 945
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  1113 RSVYSLSGGETFLISLALALGLASMAS--SKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:TIGR00618  946 RPSATLSGGETFLASLSLALALADLLStsGGTVLDSLFIDEGFGSLDEDSLDRAIGILDAIREGSKMIGIISHVPEFRER 1025
                         1210
                   ....*....|...
gi 657908800  1191 IPVQVRVQREGNG 1203
Cdd:TIGR00618 1026 IPHRILVKKTNAG 1038
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
1113-1203 7.83e-32

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 123.92  E-value: 7.83e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1113 RSVYSLSGGETFLISLALALGLASMASSKL--RIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:cd03279   119 RPVSTLSGGETFLASLSLALALSEVLQNRGgaRLEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEELKER 198
                          90
                  ....*....|...
gi 657908800 1191 IPVQVRVQREGNG 1203
Cdd:cd03279   199 IPQRLEVIKTPGG 211
AAA_23 pfam13476
AAA domain;
6-222 2.18e-26

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 107.58  E-value: 2.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     6 IRLKNLASLaGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLestsasskvPDGRNELSSNDERNL 85
Cdd:pfam13476    1 LTIENFRSF-RDQTIDF------SKGLTLITGPNGSGKTTILDAIKLALYGKTSRL---------KRKSGGGFVKGDIRI 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    86 LRRGCASGYAEVDFVGIDGHR-YRARWETRRSRDKADGALQKSQQSLQDLDTQQMlaankksefreqLEQKLGLNFAQFT 164
Cdd:pfam13476   65 GLEGKGKAYVEITFENNDGRYtYAIERSRELSKKKGKTKKKEILEILEIDELQQF------------ISELLKSDKIILP 132
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 657908800   165 RAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQR 222
Cdd:pfam13476  133 LLVFLGQEREEEFERKEKKERLEELEKALEEKEDEKKLLEKLLQLKEKKKELEELKEE 190
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
2-221 5.59e-20

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 89.30  E-value: 5.59e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    2 KILAIRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRlestsasskvpdgrnelSSND 81
Cdd:COG0419     1 KLLRLRLENFRSYRDTETIDFDD------GLNLIVGPNGAGKSTILEAIRYALYGKARS-----------------RSKL 57
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   82 ERNLLRRGCASGYAEVDFVgIDGHRYRARWetrrsrdkadgalqksqqslqdldtqqmlaankksefreqleqklglnfa 161
Cdd:COG0419    58 RSDLINVGSEEASVELEFE-HGGKRYRIER-------------------------------------------------- 86
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  162 qftravllAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQ 221
Cdd:COG0419    87 --------RQGEFAEFLEAKPSERKEALKRLLGLEIYEELKERLKELEEALESALEELAE 138
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
180-437 1.15e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.83  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  180 ASDNDRGALLEKLTDtglySQLSKAAYQRASQADEQRKQLEQRLEGSLplaeQARAGLEAALESHAQARLQEQQALQR-- 257
Cdd:NF012221 1539 ESSQQADAVSKHAKQ----DDAAQNALADKERAEADRQRLEQEKQQQL----AAISGSQSQLESTDQNALETNGQAQRda 1610
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  258 LEGQQQWFTEEqrllqscehaqgqLAEARQAWDAL-----ATERETLQWLERLApvRGLIERL-KQLEQELRHSEQQQRQ 331
Cdd:NF012221 1611 ILEESRAVTKE-------------LTTLAQGLDALdsqatYAGESGDQWRNPFA--GGLLDRVqEQLDDAKKISGKQLAD 1675
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  332 RTEQQAAgaeRLQGLQARVQEARERQAQADDHLRQAQAPLREAfQLESEARRLErTLAERQELHRQSNQRHAQQSDAarq 411
Cdd:NF012221 1676 AKQRHVD---NQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA-KADAEKRKDD-ALAKQNEAQQAESDANAAANDA--- 1747
                         250       260
                  ....*....|....*....|....*.
gi 657908800  412 ldmeQQRhvAEQAQLQAALRDSQALA 437
Cdd:NF012221 1748 ----QSR--GEQDASAAENKANQAQA 1767
 
Name Accession Description Interval E-value
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
1-1199 2.43e-99

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 340.62  E-value: 2.43e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:PRK10246    1 MKILSLRLKNLNSLKGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLNNVSQS------------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 dERNLLRRGCASGYAEVDFvGIDGHRYRARWETRRSRDKADGALQKSQQSLQDLDTQQMLaANKKSEFREQLEQKLGLNF 160
Cdd:PRK10246   68 -QNDLMTRDTAECLAEVEF-EVKGEAYRAFWSQNRARNQPDGNLQAPRVELARCADGKIL-ADKVKDKLELTATLTGLDY 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:PRK10246  145 GRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTAS 224
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:PRK10246  225 LQVLTDEEKQLLTAQQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSLAQPARQLRPHWERIQEQSA 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  321 ELRHSEqqqrqrteqqaagaERLQGLQARVQEARERQAqaddhlRQAQAPLREAFQLESEARRLERTLAERqelhrqsnq 400
Cdd:PRK10246  305 ALAHTR--------------QQIEEVNTRLQSTMALRA------RIRHHAAKQSAELQAQQQSLNTWLAEH--------- 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  401 rhaqqsDAARQLDMEQQRHVAEQAQLQaalRDSQALAALgdawathQGQLAAFVQRRqralesqAQLPELEKSLAqagep 480
Cdd:PRK10246  356 ------DRFRQWNNELAGWRAQFSQQT---SDREQLRQW-------QQQLTHAEQKL-------NALPAITLTLT----- 407
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  481 lerlqaqwaalhgsePDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQAlLDLKRQgsq 560
Cdd:PRK10246  408 ---------------ADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA-LNEMRQ--- 468
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  561 caeQVKAAEQALQVTRELLQRQrlARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLaalgEHDDQEQVRAeqALER 640
Cdd:PRK10246  469 ---RYKEKTQQLADVKTICEQE--ARIKDLEAQRAQLQAGQPCPLCGSTSHPAVEAYQAL----EPGVNQSRLD--ALEK 537
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  641 LRQTLvglregyssqrerlnqsRQEQQELTGQLAALDRQLEQWTlPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFD 720
Cdd:PRK10246  538 EVKKL-----------------GEEGAALRGQLDALTKQLQRDE-SEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQ 599
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  721 RLIARQrqtqqlqqelraaetilQQRQQALTEQRQRYEhLQQQVEEDSQQLRPLlsDEHWQRWQADPLRTFQALGESieq 800
Cdd:PRK10246  600 PWLDAQ-----------------EEHERQLRLLSQRHE-LQGQIAAHNQQIIQY--QQQIEQRQQQLLTALAGYALT--- 656
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  801 rrqqqarlqqveqrlqeLKQRCDESSWQlkqsDEQRNEARQAEERvQAELAELNGRLGAhlgqhacaqdWQLSLEHAAQA 880
Cdd:PRK10246  657 -----------------LPQEDEEASWL----ATRQQEAQSWQQR-QNELTALQNRIQQ----------LTPLLETLPQS 704
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  881 AQSAVETLQAPLDSLRE---EQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLgLSEEQATQWR 957
Cdd:PRK10246  705 DDLPHSEETVALDNWRQvheQCLSLHSQLQTLQQQDVLEAQRLQKAQAQFDTALQASVFDDQQAFLAAL-LDEETLTQLE 783
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  958 EQLQRLQEEITRQQTLEAERQAQLLQHRRQRPE-----TDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQ 1032
Cdd:PRK10246  784 QLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDgldltVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQ 863
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1033 ALLAELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGGSE-LGLLVVDTEMGDE 1111
Cdd:PRK10246  864 ALMQQIAQATQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVWLANQQLTRLHGRYLLQRKASEaLELEVVDTWQADA 943
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1112 LRSVYSLSGGETFLISLALALGLASMASSKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:PRK10246  944 VRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERI 1023

                  ....*...
gi 657908800 1192 PVQVRVQR 1199
Cdd:PRK10246 1024 PVQIKVKK 1031
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
1-1203 1.25e-57

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 217.53  E-value: 1.25e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     1 MKILAIRLKNLASLAGEQEIDFTREPlssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSASskvpdgrnelssn 80
Cdd:TIGR00618    1 MKPLRLTLKNFGSYKGTHTIDFTALG----PIFLICGKTGAGKTTLLDAITYALYGKLPRRSEVIRS------------- 63
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    81 dERNLLRRGCASGYAEVDFVgIDGHRYRARWETRRSRDKADGALQKSQQSLQDlDTQQMLAANKKSEFREQLEQKLGLNF 160
Cdd:TIGR00618   64 -LNSLYAAPSEAAFAELEFS-LGTKIYRVHRTLRCTRSHRKTEQPEQLYLEQK-KGRGRILAAKKSETEEVIHDLLKLDY 140
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:TIGR00618  141 KTFTRVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER 220
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   241 LESHAQARLQEQQALQRLEGQQQWFTEEQRLLQscehaqgqlaearqawdalaterETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQE-----------------------EQLKKQQLLKQLRARIEELRAQEA 277
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   321 ELrhseqqqrqrteqqaagaerlqglqARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQ 400
Cdd:TIGR00618  278 VL-------------------------EETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   401 RHAQQSDAARQLDMEQQRHVAEQAQLQAAlrDSQALaalgdaWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEP 480
Cdd:TIGR00618  333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAH--EVATS------IREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDI 404
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   481 LERLQAQWAALHGSEPDdlaarldelrrqtdslERQQALHKEWQQALDQRtglarRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:TIGR00618  405 LQREQATIDTRTSAFRD----------------LQGQLAHAKKQQELQQR-----YAELCAAAITCTAQCEKLEKIHLQE 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   561 CAEQVKAAEQALQVTRELLQRQrlARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLL-----AALGEHDDQEQVRAE 635
Cdd:TIGR00618  464 SAQSLKEREQQLQTKEQIHLQE--TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDnpgplTRRMQRGEQTYAQLE 541
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   636 QALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQC 715
Cdd:TIGR00618  542 TSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKL 621
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   716 QRDFDRLiarqrqtqqlqQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPlrtfQALG 795
Cdd:TIGR00618  622 QPEQDLQ-----------DVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL----QKMQ 686
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   796 ESIEQRRQQQARLQQVEQRLQELKQRcdesswqLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSle 875
Cdd:TIGR00618  687 SEKEQLTYWKEMLAQCQTLLRELETH-------IEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLK-- 757
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   876 haAQAAQSAVETLQAPLDSLREEQLrlaealehlqqqrqrqqdefqrlqadwqawrerqdnlddsrldallglseEQATQ 955
Cdd:TIGR00618  758 --ARTEAHFNNNEEVTAALQTGAEL--------------------------------------------------SHLAA 785
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   956 WREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALL 1035
Cdd:TIGR00618  786 EIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLT 865
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  1036 AELERARAEFRRWGRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQR---GGSELGLLVVDTEMGDEL 1112
Cdd:TIGR00618  866 QEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGRFHGRYADSHvnaRKYQGLALLVADAYTGSV 945
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  1113 RSVYSLSGGETFLISLALALGLASMAS--SKLRIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:TIGR00618  946 RPSATLSGGETFLASLSLALALADLLStsGGTVLDSLFIDEGFGSLDEDSLDRAIGILDAIREGSKMIGIISHVPEFRER 1025
                         1210
                   ....*....|...
gi 657908800  1191 IPVQVRVQREGNG 1203
Cdd:TIGR00618 1026 IPHRILVKKTNAG 1038
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
1113-1203 7.83e-32

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 123.92  E-value: 7.83e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1113 RSVYSLSGGETFLISLALALGLASMASSKL--RIESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHER 1190
Cdd:cd03279   119 RPVSTLSGGETFLASLSLALALSEVLQNRGgaRLEALFIDEGFGTLDPEALEAVATALELIRTENRMVGVISHVEELKER 198
                          90
                  ....*....|...
gi 657908800 1191 IPVQVRVQREGNG 1203
Cdd:cd03279   199 IPQRLEVIKTPGG 211
AAA_23 pfam13476
AAA domain;
6-222 2.18e-26

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 107.58  E-value: 2.18e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     6 IRLKNLASLaGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLestsasskvPDGRNELSSNDERNL 85
Cdd:pfam13476    1 LTIENFRSF-RDQTIDF------SKGLTLITGPNGSGKTTILDAIKLALYGKTSRL---------KRKSGGGFVKGDIRI 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    86 LRRGCASGYAEVDFVGIDGHR-YRARWETRRSRDKADGALQKSQQSLQDLDTQQMlaankksefreqLEQKLGLNFAQFT 164
Cdd:pfam13476   65 GLEGKGKAYVEITFENNDGRYtYAIERSRELSKKKGKTKKKEILEILEIDELQQF------------ISELLKSDKIILP 132
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 657908800   165 RAVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQR 222
Cdd:pfam13476  133 LLVFLGQEREEEFERKEKKERLEELEKALEEKEDEKKLLEKLLQLKEKKKELEELKEE 190
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
1-179 1.26e-23

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 100.42  E-value: 1.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAGEQEIDFTrePLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLEstsasskvpdgrnelSSN 80
Cdd:cd03279     1 MKPLKLELKNFGPFREEQVIDFT--GLDNNGLFLICGPTGAGKSTILDAITYALYGKTPRYG---------------RQE 63
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 DERNLLRRGCASgyAEVDFV-GIDGHRYRArwetrrsrdkadgalqksqqslqdldtqqmlaankksefreqlEQKLGLN 159
Cdd:cd03279    64 NLRSVFAPGEDT--AEVSFTfQLGGKKYRV-------------------------------------------ERSRGLD 98
                         170       180
                  ....*....|....*....|
gi 657908800  160 FAQFTRAVLLAQSEFSAFLK 179
Cdd:cd03279    99 YDQFTRIVLLPQGEFDRFLA 118
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
2-221 5.59e-20

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 89.30  E-value: 5.59e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    2 KILAIRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRlestsasskvpdgrnelSSND 81
Cdd:COG0419     1 KLLRLRLENFRSYRDTETIDFDD------GLNLIVGPNGAGKSTILEAIRYALYGKARS-----------------RSKL 57
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   82 ERNLLRRGCASGYAEVDFVgIDGHRYRARWetrrsrdkadgalqksqqslqdldtqqmlaankksefreqleqklglnfa 161
Cdd:COG0419    58 RSDLINVGSEEASVELEFE-HGGKRYRIER-------------------------------------------------- 86
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  162 qftravllAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQ 221
Cdd:COG0419    87 --------RQGEFAEFLEAKPSERKEALKRLLGLEIYEELKERLKELEEALESALEELAE 138
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
340-922 5.83e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.53  E-value: 5.83e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  340 AERLQGLQARVQEARERQAQADDHLRQAQAPLREAfQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRH 419
Cdd:COG1196   212 AERYRELKEELKELEAELLLLKLRELEAELEELEA-ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  420 VAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQR-RQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDD 498
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELEERLEELEEELAElEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  499 LAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTREL 578
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  579 LQRQRLARSSSVEQLRAglvdgeacpvcgsqehpyHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRER 658
Cdd:COG1196   451 EAELEEEEEALLELLAE------------------LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  659 LNQsRQEQQELTGQLAALDrqleqwTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRA 738
Cdd:COG1196   513 ALL-LAGLRGLAGAVAVLI------GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  739 AETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEhwQRWQADPLRTFQALGESIEQRRQQQARLQQVEQRLQEL 818
Cdd:COG1196   586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  819 KQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREE 898
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
                         570       580
                  ....*....|....*....|....
gi 657908800  899 QLRLAEALEHLQQQRQRQQDEFQR 922
Cdd:COG1196   744 EEELLEEEALEELPEPPDLEELER 767
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
311-1054 6.65e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 6.65e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   311 LIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQLESEA-RRLERTLA 389
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRE 309
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   390 ERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWAthqgqlAAFVQRRQRALESQAQLPE 469
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE------AELEELESRLEELEEQLET 383
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   470 LEKSLAQAGEPLERLQAQWAALhGSEPDDLAARLDELRRQTDSLERQQALHkewqqaldQRTGLARRLGELDQRMVEQEQ 549
Cdd:TIGR02168  384 LRSKVAQLELQIASLNNEIERL-EARLERLEDRRERLQQEIEELLKKLEEA--------ELKELQAELEELEEELEELQE 454
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   550 ALLDLKRQGSQCAEQVKAAEQALQVTRELLQR--QRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQ---SEQ------ 618
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQlqARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlSELisvdeg 534
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   619 ----LLAALGEH-------DDQEQVRAEQALERLRQTLVGLREgYSSQRERLNQSRQEQQeLTGQLAALDRQLEQWTLPE 687
Cdd:TIGR02168  535 yeaaIEAALGGRlqavvveNLNAAKKAIAFLKQNELGRVTFLP-LDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDP 612
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   688 ELR-LLQPSAQLEWLAQRLDELAGQRQQCQRDFdRLIARQRQTQQLQ-----QELRAAETILQQRQ------QALTEQRQ 755
Cdd:TIGR02168  613 KLRkALSYLLGGVLVVDDLDNALELAKKLRPGY-RIVTLDGDLVRPGgvitgGSAKTNSSILERRReieeleEKIEELEE 691
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   756 RYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGEsiEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQ 835
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR--KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   836 RNEARQAEERVQAELAELNGRLGAHLGQHacaqdwqlslehaaQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQR 915
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEEL--------------KALREALDELRAELTLLNEEAANLRERLESLERRIAA 835
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   916 QQDEFQRLqadwqawrerqdnlddsrldallglsEEQATQWREQLQRLQEEITRQQTL--EAERQAQLLQHRRQRPETDR 993
Cdd:TIGR02168  836 TERRLEDL--------------------------EEQIEELSEDIESLAAEIEELEELieELESELEALLNERASLEEAL 889
                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657908800   994 EALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRrwGRLNEL 1054
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ--ERLSEE 948
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
178-770 3.82e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.22  E-value: 3.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  178 LKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRlegslplaEQARAGLEAALESHAQARLQEQQALQR 257
Cdd:COG1196   218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL--------AELEAELEELRLELEELELELEEAQAE 289
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  258 LEGQQQwftEEQRLLQSCEHAQGQLAEARQAWDALATEREtlQWLERLApvrGLIERLKQLEQELRHSEQQQRQRTEQQA 337
Cdd:COG1196   290 EYELLA---ELARLEQDIARLEERRRELEERLEELEEELA--ELEEELE---ELEEELEELEEELEEAEEELEEAEAELA 361
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  338 AGAERlqgLQARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQElhrqsnqrhaqqsdaaRQLDMEQQ 417
Cdd:COG1196   362 EAEEA---LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE----------------RLERLEEE 422
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  418 RHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQwaalhgsepd 497
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR---------- 492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  498 dLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTR- 576
Cdd:COG1196   493 -LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKa 571
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  577 ---ELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGyS 653
Cdd:COG1196   572 graTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV-T 650
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  654 SQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQ 733
Cdd:COG1196   651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 657908800  734 QELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQ 770
Cdd:COG1196   731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
200-714 2.75e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.14  E-value: 2.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  200 QLSKAAYQRASQADEQRKQLEQRLEgslPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQ 279
Cdd:COG1196   281 LELEEAQAEEYELLAELARLEQDIA---RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  280 GQLAEARQAwdALATERETLQWLERLapvrgliERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQ 359
Cdd:COG1196   358 AELAEAEEA--LLEAEAELAEAEEEL-------EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE 428
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  360 ADDHLRQAQAPLREAFQ-----LESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRH-VAEQAQLQAALRDS 433
Cdd:COG1196   429 ALAELEEEEEEEEEALEeaaeeEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEADYEGFLE 508
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  434 QALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHgsepDDLAARLDELRRQTDSL 513
Cdd:COG1196   509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLK----AAKAGRATFLPLDKIRA 584
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  514 ERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLkrqgsqcAEQVKAAEQALQVTRELLQRQRLARSSSVEQL 593
Cdd:COG1196   585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR-------TLVAARLEAALRRAVTLAGRLREVTLEGEGGS 657
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  594 RAGLVDGEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQL 673
Cdd:COG1196   658 AGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL 737
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|.
gi 657908800  674 AALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQ 714
Cdd:COG1196   738 LEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
214-1014 1.02e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.33  E-value: 1.02e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   214 EQRKQLEqRLEGSLPLAEQARAgLEAALEsHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALA 293
Cdd:TIGR02168  197 ELERQLK-SLERQAEKAERYKE-LKAELR-ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   294 TERETLQwlERLAPVRGLIERLKQ----LEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQA 369
Cdd:TIGR02168  274 LEVSELE--EEIEELQKELYALANeisrLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE 351
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   370 plreafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQ 449
Cdd:TIGR02168  352 ------ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   450 LAAFVQRRQRAlESQAQLPELEKSLAQAGEPLERLQAQWAALHGS------EPDDLAARLDELRRQTDSLERQQALH--- 520
Cdd:TIGR02168  426 LLKKLEEAELK-ELQAELEELEEELEELQEELERLEEALEELREEleeaeqALDAAERELAQLQARLDSLERLQENLegf 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   521 ----KEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQ--CAEQVKAAEQALqvtrELLQRQRLARSSSVEqlr 594
Cdd:TIGR02168  505 segvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavVVENLNAAKKAI----AFLKQNELGRVTFLP--- 577
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   595 AGLVDGEACPVCGSQEHPYHQSEQLLAAlgehddqEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQE-----L 669
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAK-------DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtL 650
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   670 TGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQA 749
Cdd:TIGR02168  651 DGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   750 LTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADplrtfqalgesiEQRRQQQARLQQVEQRLQELKQRCDESSWQL 829
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE------------ERLEEAEEELAEAEAEIEELEAQIEQLKEEL 798
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   830 KQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHL 909
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   910 QqqrqrqqDEFQRLQADWQAWRERQDNLDDSRLDAllglsEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRP 989
Cdd:TIGR02168  879 L-------NERASLEEALALLRSELEELSEELREL-----ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
                          810       820
                   ....*....|....*....|....*
gi 657908800   990 ETDREALEDNLRQQRERLATSEQAY 1014
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEAR 971
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
207-1043 2.60e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 2.60e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   207 QRASQADEQRKQLEQ-RLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQScehAQGQLAEA 285
Cdd:TIGR02168  210 EKAERYKELKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE---LEEEIEEL 286
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   286 RQAWDALATERETLQwlerlAPVRGLIERLKQLEQELrhseqqqrqrteqqAAGAERLQGLQARVQEARERQAQADDHLR 365
Cdd:TIGR02168  287 QKELYALANEISRLE-----QQKQILRERLANLERQL--------------EELEAQLEELESKLDELAEELAELEEKLE 347
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   366 QAQAplreafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWAT 445
Cdd:TIGR02168  348 ELKE------ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ 421
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   446 HQGQLAAFVQRRQRAlESQAQLPELEKSLAQAGEPLERLQAQWAALHGS------EPDDLAARLDELRRQTDSLERQQAL 519
Cdd:TIGR02168  422 EIEELLKKLEEAELK-ELQAELEELEEELEELQEELERLEEALEELREEleeaeqALDAAERELAQLQARLDSLERLQEN 500
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   520 H-------KEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQ--CAEQVKAAEQALqvtrELLQRQRLARSSSV 590
Cdd:TIGR02168  501 LegfsegvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavVVENLNAAKKAI----AFLKQNELGRVTFL 576
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   591 EqlrAGLVDGEACPVCGSQEHPYHQSEQLLAAlgehddqEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQE-- 668
Cdd:TIGR02168  577 P---LDSIKGTEIQGNDREILKNIEGFLGVAK-------DLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGyr 646
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   669 ---LTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQ 745
Cdd:TIGR02168  647 ivtLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   746 RQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADplrtfqalgesiEQRRQQQARLQQVEQRLQELKQRCDES 825
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE------------ERLEEAEEELAEAEAEIEELEAQIEQL 794
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   826 SWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEA 905
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   906 LEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDD--SRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQ 983
Cdd:TIGR02168  875 LEALLNERASLEEALALLRSELEELSEELRELESkrSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954
                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657908800   984 HRRQRP---ETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARA 1043
Cdd:TIGR02168  955 EAEALEnkiEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKE 1017
46 PHA02562
endonuclease subunit; Provisional
6-432 2.66e-13

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 74.28  E-value: 2.66e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    6 IRLKNLASLaGEQEIDFTrepLSSAGLFAITGPTGAGKSTVLDALCLALFGSTPRlestsaSSKVPDGRNelsSNDERNL 85
Cdd:PHA02562    7 IRYKNILSV-GNQPIEIQ---LDKVKKTLITGKNGAGKSTMLEALTFALFGKPFR------DIKKGQLIN---SINKKDL 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   86 LrrgcasgyAEVDFvGIDGHRYRArweTRRsrdkadgalQKSQQSLQDLDTQQMLAANKKSEFREQLEQKLGLNFAQFTR 165
Cdd:PHA02562   74 L--------VELWF-EYGEKEYYI---KRG---------IKPNVFEIYCNGKLLDESASSKDFQKYFEQMLGMNYKSFKQ 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  166 AVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSK-------AAYQRASQADEQRKQLEQRL-------EGSLPLAE 231
Cdd:PHA02562  133 IVVLGTAGYVPFMQLSAPARRKLVEDLLDISVLSEMDKlnkdkirELNQQIQTLDMKIDHIQQQIktynkniEEQRKKNG 212
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  232 QARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQrllqscEHAQGQLAEARQAWDALATERETLQWLERLAPVRGL 311
Cdd:PHA02562  213 ENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI------EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGV 286
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  312 IERLKQ-LEQElrhseqqqrqrteqqaagaerlqglQARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAE 390
Cdd:PHA02562  287 CPTCTQqISEG-------------------------PDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLE 341
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 657908800  391 RQ---ELHRQSNQRHAQQSDAAR----QLDMEQQRHVAEQAQLQAALRD 432
Cdd:PHA02562  342 LKnkiSTNKQSLITLVDKAKKVKaaieELQAEFVDNAEELAKLQDELDK 390
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
664-1192 4.25e-13

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 73.65  E-value: 4.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  664 QEQQELTGQLAALDRQLEQWTlpeelrllQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETI- 742
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYA--------ELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELa 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  743 -LQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLlSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQVEQRLQELKQR 821
Cdd:COG4717   143 eLPERLEELEERLEELRELEEELEELEAELAEL-QEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  822 CDESSWQLKQSDEQRNEARQAEERVQAE-LAELNGRLGAHLGQHACAQDWQLS------------------LEHAAQAAQ 882
Cdd:COG4717   222 LEELEEELEQLENELEAAALEERLKEARlLLLIAAALLALLGLGGSLLSLILTiagvlflvlgllallfllLAREKASLG 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  883 SAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGL-------------- 948
Cdd:COG4717   302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEleqeiaallaeagv 381
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  949 -SEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQR 1027
Cdd:COG4717   382 eDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1028 REQ------SQALLAELERARAEF----RRWGRLNelIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLAR-RYRLQRGG 1096
Cdd:COG4717   462 LEQleedgeLAELLQELEELKAELrelaEEWAALK--LALELLEEAREEYREERLPPVLERASEYFSRLTDgRYRLIRID 539
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1097 SELGLLVVDTEmgDELRSVYSLSGGETFLISLALALGLASMASSklRIESLFIDEGFGSLDPESLQLAMDALDNLqAQGR 1176
Cdd:COG4717   540 EDLSLKVDTED--GRTRPVEELSRGTREQLYLALRLALAELLAG--EPLPLILDDAFVNFDDERLRAALELLAEL-AKGR 614
                         570
                  ....*....|....*.
gi 657908800 1177 KVAVISHVQEMHERIP 1192
Cdd:COG4717   615 QVIYFTCHEELVELFQ 630
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
635-1008 2.24e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 2.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  635 EQALERLRQTlvglregyssqRERLNQSRQEQQELTGQLAALDRQLEQ----WTLPEELRLLQPSA---QLEWLAQRLDE 707
Cdd:COG1196   175 EEAERKLEAT-----------EENLERLEDILGELERQLEPLERQAEKaeryRELKEELKELEAELlllKLRELEAELEE 243
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  708 LAGQRQQCQRDFDRLIARqrqtqqlqqelraaetiLQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwqadp 787
Cdd:COG1196   244 LEAELEELEAELEELEAE-----------------LAELEAELEELRLELEELELELEEAQAEEY--------------- 291
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  788 lrtfqalgESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACA 867
Cdd:COG1196   292 --------ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  868 QDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLG 947
Cdd:COG1196   364 EEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657908800  948 LSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLA 1008
Cdd:COG1196   444 LEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
101-969 2.63e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 2.63e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   101 GIDGHRYRaRWETRRSRDKADGALQKSQQSLQDLDTQ------QMLAANKKSEFREQLEQK----LGLNFAQFTRAVLLA 170
Cdd:TIGR02168  166 GISKYKER-RKETERKLERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELelalLVLRLEELREELEEL 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   171 QSEFSAF---LKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQA 247
Cdd:TIGR02168  245 QEELKEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQ 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   248 RLQEQQALQRLEGQ-QQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQwLERLAPVRGLIERLKQLEQelrhse 326
Cdd:TIGR02168  325 LEELESKLDELAEElAELEEKLEELKEELESLEAELEELEAELEELESRLEELE-EQLETLRSKVAQLELQIAS------ 397
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   327 qqqrqrteqqaagaerlqgLQARVQEARERQAQADDHLRQAQAPLREAFQLESEArRLERTLAERQELHRQSNQRHAQQS 406
Cdd:TIGR02168  398 -------------------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-ELKELQAELEELEEELEELQEELE 457
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   407 DAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQA 486
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA 537
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   487 QWAALHGSEPDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGlaRRLGELDQRMVEQEQALLDLKRQGSQCAEQVK 566
Cdd:TIGR02168  538 AIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKG--TEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   567 AAEQAL----QVTRELLQRQRLARSSSvEQLRAGLVDGEACPVCGSQehpyhqseqllaaLGEHDDQEQVRAE--QALER 640
Cdd:TIGR02168  616 KALSYLlggvLVVDDLDNALELAKKLR-PGYRIVTLDGDLVRPGGVI-------------TGGSAKTNSSILErrREIEE 681
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   641 LRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEqwtlpeelrllQPSAQLEWLAQRLDELAGQRQQCQRDFD 720
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-----------ELSRQISALRKDLARLEAEVEQLEERIA 750
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   721 RLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwqadplrtfQALGESIEQ 800
Cdd:TIGR02168  751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-------------------EALDELRAE 811
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   801 RRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQA 880
Cdd:TIGR02168  812 LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   881 AQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRER-----QDNLDDsrLDALLGLSEEQATQ 955
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlseeySLTLEE--AEALENKIEDDEEE 969
                          890
                   ....*....|....
gi 657908800   956 WREQLQRLQEEITR 969
Cdd:TIGR02168  970 ARRRLKRLENKIKE 983
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
267-1171 1.60e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 69.17  E-value: 1.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  267 EEQRLLQSCEHAQGQLAEARQAWDALATERETLqwlERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAgaERLQGL 346
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDAREQI---ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQ--RRLELL 293
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  347 QARVQEARERQAQADDHLRQAQAPLREAFQLESEARR------------LERTLAERQELHRQSNQRHAQQSDAARQLDM 414
Cdd:COG4913   294 EAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdrleqLEREIERLERELEERERRRARLEALLAALGL 373
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  415 EQQRHVAEQAQLQAALRdsQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAG----EPLERLQAQWAA 490
Cdd:COG4913   374 PLPASAEEFAALRAEAA--ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAE 451
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  491 LHGSEPDDL--AARLDELRrqtdslerqqALHKEWQQALDQRT-GLARRLgeldqrMVEQEQAlldlkrqgsqcaeqvka 567
Cdd:COG4913   452 ALGLDEAELpfVGELIEVR----------PEEERWRGAIERVLgGFALTL------LVPPEHY----------------- 498
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  568 aEQALQVTRELLQRQRL----ARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSeqLLAALGEHDDQEQVRAEQALERLRQ 643
Cdd:COG4913   499 -AAALRWVNRLHLRGRLvyerVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAW--LEAELGRRFDYVCVDSPEELRRHPR 575
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  644 --TLVGLREGYSSQRERLNQSRQEQQELTGQLAAldrqleqwtlpeelrllqpsAQLEWLAQRLDELAGQRQQCQRDFDR 721
Cdd:COG4913   576 aiTRAGQVKGNGTRHEKDDRRRIRSRYVLGFDNR--------------------AKLAALEAELAELEEELAEAEERLEA 635
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  722 LiarqrqtqqlqqelraaetilQQRQQALTEQRQRYEHLQQQVEEDSQqlrpllsdehWQRWQADplrtfqalgesieqr 801
Cdd:COG4913   636 L---------------------EAELDALQERREALQRLAEYSWDEID----------VASAERE--------------- 669
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  802 rqqqarlqqvEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAA 881
Cdd:COG4913   670 ----------IAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  882 QSAV---------ETLQAPLDSLREEQLR--LAEALEHLQQQRQRQQDEFQRLQADW-QAWRERQDNLDDSrldallgls 949
Cdd:COG4913   740 EDLArlelralleERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMRAFnREWPAETADLDAD--------- 810
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  950 EEQATQWREQLQRLQEEITrqqtleAERQAQLLQHRRQRPETDRE----ALEDNLRQQRERLATSEQA------YLDTYS 1019
Cdd:COG4913   811 LESLPEYLALLDRLEEDGL------PEYEERFKELLNENSIEFVAdllsKLRRAIREIKERIDPLNDSlkripfGPGRYL 884
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1020 QLQADNQRREQSQALLAELERARAefrrwgRLNELIGSSSGDKFRRIAQgyNLDLLVQHSNVQLRQLARRYRLQRGGSEL 1099
Cdd:COG4913   885 RLEARPRPDPEVREFRQELRAVTS------GASLFDEELSEARFAALKR--LIERLRSEEEESDRRWRARVLDVRNHLEF 956
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1100 GLLVVDTEmGDELRSVYS----LSGGET-----FLI--SLALALGLASMASSKLRIesLFIDEGFGSLDPESLQLAMDAL 1168
Cdd:COG4913   957 DAEEIDRE-DGEEVETYSssggKSGGEKqklayFILaaALAYQLGLEGRGRPSFRT--VVLDEAFSKMDEEFARRALRLF 1033

                  ...
gi 657908800 1169 DNL 1171
Cdd:COG4913  1034 KEL 1036
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
1117-1206 1.04e-10

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 62.62  E-value: 1.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1117 SLSGGETFLISLALALGLASMASSKLRIesLFIDEGFGSLDPESLQLAM-DALDNLQAQG-RKVAVISHVQEMHERIPVQ 1194
Cdd:cd03240   115 RCSGGEKVLASLIIRLALAETFGSNCGI--LALDEPTTNLDEENIEESLaEIIEERKSQKnFQLIVITHDEELVDAADHI 192
                          90
                  ....*....|..
gi 657908800 1195 VRVQREGNGMSS 1206
Cdd:cd03240   193 YRVEKDGRQKSR 204
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
3-110 1.76e-10

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 61.85  E-value: 1.76e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    3 ILAIRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRleSTSASSKVPDgrnelssnde 82
Cdd:cd03240     1 IDKLSIRNIRSFHERSEIEFFS------PLTLIVGQNGAGKTTIIEALKYALTGELPP--NSKGGAHDPK---------- 62
                          90       100
                  ....*....|....*....|....*...
gi 657908800   83 rnLLRRGCASGYAEVDFVGIDGHRYRAR 110
Cdd:cd03240    63 --LIREGEVRAQVKLAFENANGKKYTIT 88
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
743-1047 3.70e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 3.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   743 LQQRQQALTEQRQRYEHLQQQVE--EDSQQLRPLLSDEHWQRWQADplrtFQALGESIEQRRQQQARLQQVEQRLQELKQ 820
Cdd:TIGR02168  188 LDRLEDILNELERQLKSLERQAEkaERYKELKAELRELELALLVLR----LEELREELEELQEELKEAEEELEELTAELQ 263
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   821 RCDEsswQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQL 900
Cdd:TIGR02168  264 ELEE---KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   901 RLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDS--RLDALLGLSEEQATQWREQLQRLQEEITRQQtleaERQ 978
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQleTLRSKVAQLELQIASLNNEIERLEARLERLE----DRR 416
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 657908800   979 AQLLQhrrQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRR 1047
Cdd:TIGR02168  417 ERLQQ---EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
1118-1205 4.81e-09

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 56.60  E-value: 4.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1118 LSGGETFLISLALALGLASMASSKLRIeslfIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQVRV 1197
Cdd:cd03227    78 LSGGEKELSALALILALASLKPRPLYI----LDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELAELADKLIHI 153

                  ....*...
gi 657908800 1198 QREGNGMS 1205
Cdd:cd03227   154 KKVITGVY 161
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
266-789 5.06e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.70  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  266 TEEQR--LLQSCEHAQgQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQElrhseqqqrqrteqqaagaerL 343
Cdd:COG4913   247 AREQIelLEPIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAE---------------------L 304
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  344 QGLQARVQEARERQAQADDHLRQAQAPLREAF-----QLESEARRLERTLAERQelhrqsnQRHAQQSDAARQLDMEQQR 418
Cdd:COG4913   305 ARLEAELERLEARLDALREELDELEAQIRGNGgdrleQLEREIERLERELEERE-------RRRARLEALLAALGLPLPA 377
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  419 HVAEQAQLQAALRdsQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAG----EPLERLQAQWAALHGS 494
Cdd:COG4913   378 SAEEFAALRAEAA--ALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGL 455
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  495 EPDDL--AARLDELRrqtdslerqqALHKEWQQAL--------------DQRTGLARRL-------GELD-QRMVEQEQA 550
Cdd:COG4913   456 DEAELpfVGELIEVR----------PEEERWRGAIervlggfaltllvpPEHYAAALRWvnrlhlrGRLVyERVRTGLPD 525
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  551 LLDLKRQGSQCAEQVKAAEQALQ--VTRELLQRQRLARSSSVEQLR--------AGLVDGEacpvcgsqehpyhqseqll 620
Cdd:COG4913   526 PERPRLDPDSLAGKLDFKPHPFRawLEAELGRRFDYVCVDSPEELRrhpraitrAGQVKGN------------------- 586
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  621 AALGEHDDQEQVR--------AEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWtlPEELRLL 692
Cdd:COG4913   587 GTRHEKDDRRRIRsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS--WDEIDVA 664
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  693 QpsaqlewLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLR 772
Cdd:COG4913   665 S-------AEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE 737
                         570
                  ....*....|....*...
gi 657908800  773 PLLSD-EHWQRWQADPLR 789
Cdd:COG4913   738 AAEDLaRLELRALLEERF 755
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
668-1039 1.06e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.69  E-value: 1.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   668 ELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARqrqtqqlqqelraaETILQQRQ 747
Cdd:TIGR02168  197 ELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE--------------LEELTAEL 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   748 QALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwqadplRTFQALGESIEQrrqqqarlqqVEQRLQELKQRCDESSW 827
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQ----------------KELYALANEISR----------LEQQKQILRERLANLER 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   828 QLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALE 907
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   908 HLQQQRQRQQDEFQRLQadwqawrERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQtleaerqaqllqhrrq 987
Cdd:TIGR02168  397 SLNNEIERLEARLERLE-------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQ---------------- 453
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 657908800   988 rpeTDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELE 1039
Cdd:TIGR02168  454 ---EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
811-1044 1.23e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  811 VEQRLQELKQRCDESSWQLKQSDEQRNEARQAEErVQAELAELNGRLGAHLGQHACAQDWQL-----SLEHAAQAAQSAV 885
Cdd:COG1196   184 TEENLERLEDILGELERQLEPLERQAEKAERYRE-LKEELKELEAELLLLKLRELEAELEELeaeleELEAELEELEAEL 262
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  886 ETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDS--RLDALLGLSEEQATQWREQLQRL 963
Cdd:COG1196   263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEEL 342
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  964 QEEITRQQTLEAERQAQLLQHRRQRPETDREALE--DNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERA 1041
Cdd:COG1196   343 EEELEEAEEELEEAEAELAEAEEALLEAEAELAEaeEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                  ...
gi 657908800 1042 RAE 1044
Cdd:COG1196   423 LEE 425
PTZ00121 PTZ00121
MAEBL; Provisional
112-844 2.61e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 2.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  112 ETRRSRDKADGALQKSQQSLQDLDTQQMlaanKKSEFREQLEQKLGLnfAQFTRAVLLAQSEFSAFLKASdndrgalLEK 191
Cdd:PTZ00121 1057 EGKAEAKAHVGQDEGLKPSYKDFDFDAK----EDNRADEATEEAFGK--AEEAKKTETGKAEEARKAEEA-------KKK 1123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  192 LTDTGLYSQLSKAayQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRL 271
Cdd:PTZ00121 1124 AEDARKAEEARKA--EDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARK 1201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  272 LQSCEHAQG--QLAEARQAWDALATERetlqwLERLAPVRGLIERLKQLEQElRHSEQQQRQRTEQQAAGAERLQGLQAr 349
Cdd:PTZ00121 1202 AEAARKAEEerKAEEARKAEDAKKAEA-----VKKAEEAKKDAEEAKKAEEE-RNNEEIRKFEEARMAHFARRQAAIKA- 1274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  350 vQEARERqaqadDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRhvAEQAQLQAA 429
Cdd:PTZ00121 1275 -EEARKA-----DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK--AEEAKKAAE 1346
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  430 LRDSQALAALGDAWATHQGQLAAFVQR---RQRALESQAQLPELEKSlAQAGEPLERLQAQWAALHGSEPDDLAArlDEL 506
Cdd:PTZ00121 1347 AAKAEAEAAADEAEAAEEKAEAAEKKKeeaKKKADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKA--DEA 1423
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  507 RRQTDSLERQQALHKEWQQA-----LDQRTGLARRLGELDQRMVEQEQALlDLKRQgsqcAEQVKAAEQALQVTRELLQR 581
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKKAEEAkkadeAKKKAEEAKKAEEAKKKAEEAKKAD-EAKKK----AEEAKKADEAKKKAEEAKKK 1498
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  582 QRLARSSSVEQLRAGlvdgEAcpvcgSQEHPYHQSEQLLAALGEHDDQEQVRAEQA--LERLRQTlVGLREGYSSQRERL 659
Cdd:PTZ00121 1499 ADEAKKAAEAKKKAD----EA-----KKAEEAKKADEAKKAEEAKKADEAKKAEEKkkADELKKA-EELKKAEEKKKAEE 1568
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  660 NQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEW-LAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRA 738
Cdd:PTZ00121 1569 AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAeEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK 1648
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  739 AEtilqQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQVEQRLQEL 818
Cdd:PTZ00121 1649 AE----ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724
                         730       740
                  ....*....|....*....|....*.
gi 657908800  819 KQRCDESSWQLKQSDEQrnEARQAEE 844
Cdd:PTZ00121 1725 EEENKIKAEEAKKEAEE--DKKKAEE 1748
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
503-1047 5.38e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 5.38e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   503 LDELRRQTDSLERQ--------------------------QALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKR 556
Cdd:TIGR02168  195 LNELERQLKSLERQaekaerykelkaelrelelallvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   557 QGSQCAEQVKAAEQALQVTRELLQR---------QRLARS-SSVEQLRAGLVDGEACPVCgSQEHPYHQSEQLLAALGEH 626
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRleqqkqilrERLANLeRQLEELEAQLEELESKLDE-LAEELAELEEKLEELKEEL 353
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   627 DDQ--EQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQ--------WTLPEELRLLQPSA 696
Cdd:TIGR02168  354 ESLeaELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrrerlQQEIEELLKKLEEA 433
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   697 QLEWLAQRLDELAGQRQQCQRDFDRLIArqrQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLS 776
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEE---ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA 510
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   777 DEHWQRWQADplrTFQALGESIEQRRQQQARLQQV-EQRLQELKQRCDESSWQLKQSDEQRNEARQAE-ERVQAELAELN 854
Cdd:TIGR02168  511 LLKNQSGLSG---ILGVLSELISVDEGYEAAIEAAlGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFlPLDSIKGTEIQ 587
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   855 GRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETL---------------------------------------------- 888
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnalelakklrpgyrivtldgdlvrpggvitggsak 667
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   889 --------QAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDD--SRLDALLGLSEEQATQWRE 958
Cdd:TIGR02168  668 tnssilerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRqiSALRKDLARLEAEVEQLEE 747
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   959 QLQRLQEEITRQQTLEAERQAQL--LQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLA 1036
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLeeAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827
                          650
                   ....*....|.
gi 657908800  1037 ELERARAEFRR 1047
Cdd:TIGR02168  828 SLERRIAATER 838
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
1083-1195 1.07e-07

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 52.63  E-value: 1.07e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1083 LRQLARRYRLQRGGSELGLLVVDTEMGDELRS----VYSLSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDP 1158
Cdd:cd00267    42 LRAIAGLLKPTSGEILIDGKDIAKLPLEELRRrigyVPQLSGGQRQRVALARAL----LLNPDL----LLLDEPTSGLDP 113
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 657908800 1159 ESLQLAMDALDNLQAQGRKVAVISHVQEMHERIPVQV 1195
Cdd:cd00267   114 ASRERLLELLRELAEEGRTVIIVTHDPELAELAADRV 150
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
5-97 2.40e-07

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 51.59  E-value: 2.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    5 AIRLKNLASLAGEQEIDFTREPLssaglFAITGPTGAGKSTVLDALCLALFGSTPRLEStsaSSKVPDGRNELSSNDERN 84
Cdd:cd03227     1 KIVLGRFPSYFVPNDVTFGEGSL-----TIITGPNGSGKSTILDAIGLALGGAQSATRR---RSGVKAGCIVAAVSAELI 72
                          90
                  ....*....|...
gi 657908800   85 LLRRGCASGYAEV 97
Cdd:cd03227    73 FTRLQLSGGEKEL 85
PTZ00121 PTZ00121
MAEBL; Provisional
267-1027 3.12e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  267 EEQRLLQSCEHAQGQLAEARQAWDALATE-RETLQWLERLAPVRGlIERLKQLE-----QELRHSEQQQRQRTEQQAAGA 340
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEaRKAEEAKKKAEDARK-AEEARKAEdarkaEEARKAEDAKRVEIARKAEDA 1163
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  341 ERLQgLQARVQEARE-RQAQADDHLRQAQApLREAfqleSEARRLERtlAERQELHRQSNQrhAQQSDAARQLD----ME 415
Cdd:PTZ00121 1164 RKAE-EARKAEDAKKaEAARKAEEVRKAEE-LRKA----EDARKAEA--ARKAEEERKAEE--ARKAEDAKKAEavkkAE 1233
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  416 QQRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQ-RALESQAQLPELEKS--LAQAGEPLERLQAQWAALH 492
Cdd:PTZ00121 1234 EAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEaRKADELKKAEEKKKAdeAKKAEEKKKADEAKKKAEE 1313
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  493 GSEPDDLAARLDELRRQTDSLERQ--------QALHKEWQQALDQRTGlARRLGELDQRMVEQEQALLD-LKRQgsqcAE 563
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKaeeakkaaEAAKAEAEAAADEAEA-AEEKAEAAEKKKEEAKKKADaAKKK----AE 1388
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  564 QVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQ 643
Cdd:PTZ00121 1389 EKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE 1468
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  644 TLVGLR-EGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPsaqlewlAQRLDELagQRQQCQRDFDRl 722
Cdd:PTZ00121 1469 AKKADEaKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE-------AKKADEA--KKAEEAKKADE- 1538
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  723 iARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRpllsdehwqrwQADPLRTFQALGESIEQRR 802
Cdd:PTZ00121 1539 -AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK-----------KAEEARIEEVMKLYEEEKK 1606
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  803 QQQARLQQVEQ---RLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAElaELNGRLGAHLGQHACAQDWQLS-LEHAA 878
Cdd:PTZ00121 1607 MKAEEAKKAEEakiKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE--EENKIKAAEEAKKAEEDKKKAEeAKKAE 1684
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  879 QAAQSAVETLQAPLDSLRE-EQLRLAEALEHLQQQRQRQQDEFQRLQADwQAWRErqdnlddsrldallglsEEQATQWR 957
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKaEELKKKEAEEKKKAEELKKAEEENKIKAE-EAKKE-----------------AEEDKKKA 1746
                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  958 EQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQR 1027
Cdd:PTZ00121 1747 EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
1027-1184 5.09e-07

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 51.55  E-value: 5.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1027 RREQSQALlAELERARAEFRRwgRLNELIGSSSGDKFRRIAQGYNLDLLVQHSNVQLRQLARRYRLQRGgselgllvvdt 1106
Cdd:COG0419    85 ERRQGEFA-EFLEAKPSERKE--ALKRLLGLEIYEELKERLKELEEALESALEELAELQKLKQEILAQL----------- 150
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 657908800 1107 emgDELRSVYSLSGGETflislaLALGLASMASsklriesLFIDegFGSLDPESLQLAMDALDNLQaqgrkvaVISHV 1184
Cdd:COG0419   151 ---SGLDPIETLSGGER------LRLALADLLS-------LILD--FGSLDEERLERLLDALEELA-------IITHV 203
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
208-859 5.10e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.19  E-value: 5.10e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  208 RASQADEQRKQLEQRLEgslplaeQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQ 287
Cdd:COG3096   362 RLEEQEEVVEEAAEQLA-------EAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDL 434
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  288 AWDALATERETLQwlerlAPVRGLIERLKQLEQELRHSEQQQR------QRTEQQAAGAERLQGLQARVQ---EARERQA 358
Cdd:COG3096   435 TPENAEDYLAAFR-----AKEQQATEEVLELEQKLSVADAARRqfekayELVCKIAGEVERSQAWQTAREllrRYRSQQA 509
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  359 QADdHLRQAQAPLREAFQLESEARRLERTLAErqelhrqSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAA 438
Cdd:COG3096   510 LAQ-RLQQLRAQLAELEQRLRQQQNAERLLEE-------FCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRS 581
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  439 lgdAWATHQGQLAAFVQR-RQRA---LESQAQLPELEkslAQAGEPLERLQAQWAALHgsepdDLAARLDELRRQTDSL- 513
Cdd:COG3096   582 ---ELRQQLEQLRARIKElAARApawLAAQDALERLR---EQSGEALADSQEVTAAMQ-----QLLEREREATVERDELa 650
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  514 ERQQALHKEWQQ------ALDQR-TGLARRLG-----------------ELDQRMVEQEQALL--DLKRQGSQ------C 561
Cdd:COG3096   651 ARKQALESQIERlsqpggAEDPRlLALAERLGgvllseiyddvtledapYFSALYGPARHAIVvpDLSAVKEQlagledC 730
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  562 AEQV---------------KAAEQALQVTRELLQRQ-------------RLARSSSVEQLRA---GLVDGEACPVCGSQE 610
Cdd:COG3096   731 PEDLyliegdpdsfddsvfDAEELEDAVVVKLSDRQwrysrfpevplfgRAAREKRLEELRAerdELAEQYAKASFDVQK 810
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  611 HP--YHQSEQLlaaLGEHDDQE-QVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPE 687
Cdd:COG3096   811 LQrlHQAFSQF---VGGHLAVAfAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLA 887
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  688 ElrllqpsaqlEWLAQRLDELAGQRQQCQRDfDRLIARQRQTQQLQQELRAAetiLQQRQQALTEQRQRYEHLQQQVEED 767
Cdd:COG3096   888 D----------ETLADRLEELREELDAAQEA-QAFIQQHGKALAQLEPLVAV---LQSDPEQFEQLQADYLQAKEQQRRL 953
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  768 SQQLRPLlsDEHWQRwqadplRTFQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQaeervq 847
Cdd:COG3096   954 KQQIFAL--SEVVQR------RPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQ------ 1019
                         730
                  ....*....|..
gi 657908800  848 aELAELNGRLGA 859
Cdd:COG3096  1020 -VLASLKSSRDA 1030
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
6-1044 5.32e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 5.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPR-LESTSASSKVPDGRNELSSNDern 84
Cdd:TIGR02169    5 IELENFKSFGKKKVIPFSK------GFTVISGPNGSGKSNIGDAILFALGLSSSKaMRAERLSDLISNGKNGQSGNE--- 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    85 llrrgcasGYAEVDFvGIDGHRYRARWETRRSRDKADgalqKSQQSLQDLDTQqmlaANKKSEFREQLeQKLGLNFAQFT 164
Cdd:TIGR02169   76 --------AYVTVTF-KNDDGKFPDELEVVRRLKVTD----DGKYSYYYLNGQ----RVRLSEIHDFL-AAAGIYPEGYN 137
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   165 ravLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQA-----------DEQRKQLEqRLEGSLPLAEQA 233
Cdd:TIGR02169  138 ---VVLQGDVTDFISMSPVERRKIIDEIAGVAEFDRKKEKALEELEEVeenierldliiDEKRQQLE-RLRREREKAERY 213
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   234 RAGLEAALESHAQARLQEQQA-----------LQRLEGQQQWFTEE-QRLLQSCEHAQGQLAEARQAWDALaTERETLQW 301
Cdd:TIGR02169  214 QALLKEKREYEGYELLKEKEAlerqkeaierqLASLEEELEKLTEEiSELEKRLEEIEQLLEELNKKIKDL-GEEEQLRV 292
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   302 LERLAPVRGLIERLKQ----LEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQ- 376
Cdd:TIGR02169  293 KEKIGELEAEIASLERsiaeKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAe 372
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   377 ---LESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQAlaalgdawathqgQLAAF 453
Cdd:TIGR02169  373 leeVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-------------KINEL 439
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   454 VQRRqraLESQAQLPELEKSLAQAGEPLERLQAQWAALHgSEPDDLAARLDELRRQTDSLE-RQQALHKEWQQALDQRT- 531
Cdd:TIGR02169  440 EEEK---EDKALEIKKQEWKLEQLAADLSKYEQELYDLK-EEYDRVEKELSKLQRELAEAEaQARASEERVRGGRAVEEv 515
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   532 ---------GLARRLGELDQRMVEQ-EQALldlkrqGSQCAEQVKAAEQALQVTRELLQRQRLARSS--SVEQLRAGLVD 599
Cdd:TIGR02169  516 lkasiqgvhGTVAQLGSVGERYATAiEVAA------GNRLNNVVVEDDAVAKEAIELLKRRKAGRATflPLNKMRDERRD 589
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   600 GEACPVCGSQEHPYHqseqllaaLGEHDDQEQVRAEQAlerLRQTLVglREGYSSQRERLNQSRQ-----EQQELTGQLA 674
Cdd:TIGR02169  590 LSILSEDGVIGFAVD--------LVEFDPKYEPAFKYV---FGDTLV--VEDIEAARRLMGKYRMvtlegELFEKSGAMT 656
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   675 ALDRQLEQwtlpEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQR 754
Cdd:TIGR02169  657 GGSRAPRG----GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   755 QRYEHLQQQVEEDSQQLRPLLSDEHwqrwqadplrtfQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQlkQSDE 834
Cdd:TIGR02169  733 EKLKERLEELEEDLSSLEQEIENVK------------SELKELEARIEELEEDLHKLEEALNDLEARLSHSRIP--EIQA 798
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   835 QRNEARQAEERVQAELAELNGRLGAHLGQHACA-------QDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALE 907
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeiqelQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   908 HLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDAllglsEEQATQWREQLQRLQEEITR--------QQTLEAERQA 979
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK-----RKRLSELKAKLEALEEELSEiedpkgedEEIPEEELSL 953
                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657908800   980 QLLQHRRQRPETDREALED-NLRQQRErLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAE 1044
Cdd:TIGR02169  954 EDVQAELQRVEEEIRALEPvNMLAIQE-YEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
1113-1170 7.97e-07

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 48.39  E-value: 7.97e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657908800  1113 RSVYSLSGGET-FLISLALALGLASMASSKL----RIESLFIDEGFGSLDPESLQLAMDALDN 1170
Cdd:pfam13558   28 RRSGGLSGGEKqLLAYLPLAAALAAQYGSAEgrppAPRLVFLDEAFAKLDEENIRTALELLRA 90
mukB PRK04863
chromosome partition protein MukB;
371-722 1.21e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  371 LREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQL 450
Cdd:PRK04863  285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEERL 364
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  451 AAFVQRRQralESQAQLPELEKSLAQAGEPLERLQAQWAalhgsepdDLAARLDELrrQTDSLERQQALH-----KEWQQ 525
Cdd:PRK04863  365 EEQNEVVE---EADEQQEENEARAEAAEEEVDELKSQLA--------DYQQALDVQ--QTRAIQYQQAVQaleraKQLCG 431
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  526 ALD-QRTGLARRLGELDQRMVEQEQALLDLKRQGS----------QCAEQVKAA------EQALQVTRELLQRQRLAR-- 586
Cdd:PRK04863  432 LPDlTADNAEDWLEEFQAKEQEATEELLSLEQKLSvaqaahsqfeQAYQLVRKIagevsrSEAWDVARELLRRLREQRhl 511
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  587 SSSVEQLRAGLVDGEacpvcgsQEHPYHQS-EQLLAALG-----EHDDQEQVraEQALERLRQTLVGLREGYSSQRERLN 660
Cdd:PRK04863  512 AEQLQQLRMRLSELE-------QRLRQQQRaERLLAEFCkrlgkNLDDEDEL--EQLQEELEARLESLSESVSEARERRM 582
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  661 QSRQEQQELTGQLAALDRQLEQW-TLPEELRLLQP--------SAQLEWLAQRL-----------DELAGQRQQCQRDFD 720
Cdd:PRK04863  583 ALRQQLEQLQARIQRLAARAPAWlAAQDALARLREqsgeefedSQDVTEYMQQLlerereltverDELAARKQALDEEIE 662

                  ..
gi 657908800  721 RL 722
Cdd:PRK04863  663 RL 664
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
276-772 5.46e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 5.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  276 EHAQGQLAEARQAWDALAteretlqwlERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARE 355
Cdd:PRK02224  223 ERYEEQREQARETRDEAD---------EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE 293
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  356 R--QAQADDHLRQAQAPLREAFQLESEARRLErtLAERQELHRQSNQRHAQQSDAARQlDMEQQRHVAEQAQLQAALRDS 433
Cdd:PRK02224  294 ErdDLLAEAGLDDADAEAVEARREELEDRDEE--LRDRLEECRVAAQAHNEEAESLRE-DADDLEERAEELREEAAELES 370
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  434 QALAAlgdawathqgqLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHgSEPDDLAARLDELRRQTDSL 513
Cdd:PRK02224  371 ELEEA-----------REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELR-EERDELREREAELEATLRTA 438
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  514 ERQQAlhkEWQQALD-----------QRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTREL--LQ 580
Cdd:PRK02224  439 RERVE---EAEALLEagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIerLE 515
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  581 RQRLARSSSVEQLRAGLVDGEacpvcgsqehpyHQSEQLLAALGEHDDQEQVRAEQALErlrqtlvgLREGYSSQRERLN 660
Cdd:PRK02224  516 ERREDLEELIAERRETIEEKR------------ERAEELRERAAELEAEAEEKREAAAE--------AEEEAEEAREEVA 575
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  661 QSRQEQQELTGQLAALDRQLEQWTLPEELRllqpsAQLEWLAQRLDELAGQRQQCQrdfDRLiarqrqTQQLQQELRAAE 740
Cdd:PRK02224  576 ELNSKLAELKERIESLERIRTLLAAIADAE-----DEIERLREKREALAELNDERR---ERL------AEKRERKRELEA 641
                         490       500       510
                  ....*....|....*....|....*....|..
gi 657908800  741 TILQQRQQALTEQRQRYEHLQQQVEEDSQQLR 772
Cdd:PRK02224  642 EFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
834-1047 5.84e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 5.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  834 EQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQR 913
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  914 QRQQDEFQRL---------QADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTlEAERQAQLLQH 984
Cdd:COG4942   100 EAQKEELAELlralyrlgrQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA-ELEAERAELEA 178
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 657908800  985 RRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRR 1047
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
COG3903 COG3903
Predicted ATPase [General function prediction only];
205-659 6.37e-06

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 50.79  E-value: 6.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  205 AYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQrllqscEHAQGQLAE 284
Cdd:COG3903   477 AAERLAEAGERAAARRRHADYYLALAERAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDA------ELALRLAAA 550
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  285 ARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHL 364
Cdd:COG3903   551 LAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALA 630
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  365 RQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWA 444
Cdd:COG3903   631 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAA 710
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  445 THQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDDLAARLDELRRQTDSLERQQALHKEWQ 524
Cdd:COG3903   711 LAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAA 790
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  525 QALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVDGEACP 604
Cdd:COG3903   791 AAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAAL 870
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 657908800  605 VCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERL 659
Cdd:COG3903   871 AAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAA 925
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
230-1005 9.49e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 9.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  230 AEQARAGLEAALEshaqARLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQ-AWDALATERETLQWLERLAPV 308
Cdd:COG3096   277 ANERRELSERALE----LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQaASDHLNLVQTALRQQEKIERY 352
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  309 RgliERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQA---QADDHL-------RQAQAPLREAFQLE 378
Cdd:COG3096   353 Q---EDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqQALDVQqtraiqyQQAVQALEKARALC 429
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  379 SEARRLERTLAERQELHRqsnqRHAQQSDAARqLDMEQQRHVAEQA--QLQAALRDSQALAA---LGDAWATHQGQLAAF 453
Cdd:COG3096   430 GLPDLTPENAEDYLAAFR----AKEQQATEEV-LELEQKLSVADAArrQFEKAYELVCKIAGeveRSQAWQTARELLRRY 504
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  454 VQRR---QRALESQAQLPELEKSLAQAGEpLERLQAQWAALHG---SEPDDLAARLDELRRQTDSLERQQALHKEWQQAL 527
Cdd:COG3096   505 RSQQalaQRLQQLRAQLAELEQRLRQQQN-AERLLEEFCQRIGqqlDAAEELEELLAELEAQLEELEEQAAEAVEQRSEL 583
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  528 DQRTG-LARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRlARSSSVEQLRAglvdgeacpvc 606
Cdd:COG3096   584 RQQLEqLRARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLERER-EATVERDELAA----------- 651
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  607 gSQEHPYHQSEQLLAALGEHDDQEQVRAEQA-----------------------------------LERLRQTLVGLREG 651
Cdd:COG3096   652 -RKQALESQIERLSQPGGAEDPRLLALAERLggvllseiyddvtledapyfsalygparhaivvpdLSAVKEQLAGLEDC 730
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  652 ----YSSQRE--RLNQSRQEQQELTGQLAAL--DRQLEQWTLPE---------ELRLLQPSAQLEWLAQRLDELAGQRQQ 714
Cdd:COG3096   731 pedlYLIEGDpdSFDDSVFDAEELEDAVVVKlsDRQWRYSRFPEvplfgraarEKRLEELRAERDELAEQYAKASFDVQK 810
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  715 CQR---DFDRLIAR----------QRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVeEDSQQLRP---LLSDE 778
Cdd:COG3096   811 LQRlhqAFSQFVGGhlavafapdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQL-QLLNKLLPqanLLADE 889
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  779 HwqrwqadplrtfqaLGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLK--QSDEQRNEARQAE-ERVQAELAELNG 855
Cdd:COG3096   890 T--------------LADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAvlQSDPEQFEQLQADyLQAKEQQRRLKQ 955
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  856 RLGA--HLGQHACAQDWQLSLEHAAQaAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRER 933
Cdd:COG3096   956 QIFAlsEVVQRRPHFSYEDAVGLLGE-NSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQT 1034
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657908800  934 QDNLDDSRLDALLGLSEEQATQWREQLQRLQEEI--TRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRE 1005
Cdd:COG3096  1035 LQELEQELEELGVQADAEAEERARIRRDELHEELsqNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQERE 1108
ABC_SMC_head cd03239
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ...
3-99 1.15e-05

The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.


Pssm-ID: 213206 [Multi-domain]  Cd Length: 178  Bit Score: 47.30  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    3 ILAIRLKNLASLAGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTSasskvpdgrnELSSNDE 82
Cdd:cd03239     1 IKQITLKNFKSYRDETVVGG------SNSFNAIVGPNGSGKSNIVDAICFVLGGKAAKLRRGS----------LLFLAGG 64
                          90
                  ....*....|....*..
gi 657908800   83 RNllRRGCASGYAEVDF 99
Cdd:cd03239    65 GV--KAGINSASVEITF 79
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
180-437 1.15e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.83  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  180 ASDNDRGALLEKLTDtglySQLSKAAYQRASQADEQRKQLEQRLEGSLplaeQARAGLEAALESHAQARLQEQQALQR-- 257
Cdd:NF012221 1539 ESSQQADAVSKHAKQ----DDAAQNALADKERAEADRQRLEQEKQQQL----AAISGSQSQLESTDQNALETNGQAQRda 1610
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  258 LEGQQQWFTEEqrllqscehaqgqLAEARQAWDAL-----ATERETLQWLERLApvRGLIERL-KQLEQELRHSEQQQRQ 331
Cdd:NF012221 1611 ILEESRAVTKE-------------LTTLAQGLDALdsqatYAGESGDQWRNPFA--GGLLDRVqEQLDDAKKISGKQLAD 1675
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  332 RTEQQAAgaeRLQGLQARVQEARERQAQADDHLRQAQAPLREAfQLESEARRLErTLAERQELHRQSNQRHAQQSDAarq 411
Cdd:NF012221 1676 AKQRHVD---NQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA-KADAEKRKDD-ALAKQNEAQQAESDANAAANDA--- 1747
                         250       260
                  ....*....|....*....|....*.
gi 657908800  412 ldmeQQRhvAEQAQLQAALRDSQALA 437
Cdd:NF012221 1748 ----QSR--GEQDASAAENKANQAQA 1767
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
198-722 1.93e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 1.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  198 YSQLSKAAYQRAsQADEQRKQLEQRLEGSLPLA----------EQARAGLEAALESHAQARLQEQQALQRLEGQQQ---- 263
Cdd:COG3096   521 LAELEQRLRQQQ-NAERLLEEFCQRIGQQLDAAeeleellaelEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKelaa 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  264 ----WFTEEQRLLQSCEHAQGQLAEARQAWDALAT--ERETLQWLERlapvRGLIERLKQLEQELRHSEQQQRQRTEQQA 337
Cdd:COG3096   600 rapaWLAAQDALERLREQSGEALADSQEVTAAMQQllEREREATVER----DELAARKQALESQIERLSQPGGAEDPRLL 675
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  338 AGAERLQGL------------QARVQEAR---ERQA-------QADDHLRQAQAPLREAFQLESEARRLERTLAERQELH 395
Cdd:COG3096   676 ALAERLGGVllseiyddvtleDAPYFSALygpARHAivvpdlsAVKEQLAGLEDCPEDLYLIEGDPDSFDDSVFDAEELE 755
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  396 R----QSNQRHAQQSD---------AARQLDMEQQRHVAEQ-----AQLQAALRDSQALAALGDAWATHQGQLA------ 451
Cdd:COG3096   756 DavvvKLSDRQWRYSRfpevplfgrAAREKRLEELRAERDElaeqyAKASFDVQKLQRLHQAFSQFVGGHLAVAfapdpe 835
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  452 -AFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGS-------EPDDLAARLDELRRQTDSLERQQALHKEW 523
Cdd:COG3096   836 aELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLlpqanllADETLADRLEELREELDAAQEAQAFIQQH 915
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  524 QQALDQrtgLARRLGELDQRMVEQEQalldLKRQGSQCAEQVKAAEQALQVTRELLQR----------QRLARSSS-VEQ 592
Cdd:COG3096   916 GKALAQ---LEPLVAVLQSDPEQFEQ----LQADYLQAKEQQRRLKQQIFALSEVVQRrphfsyedavGLLGENSDlNEK 988
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  593 LRAGLVdgeacpvcgsqehpyhQSEQLLAALGEHDDQEQVRAEQALerlrQTLVGLREGYSSQRERLNQSRQEQQELTGQ 672
Cdd:COG3096   989 LRARLE----------------QAEEARREAREQLRQAQAQYSQYN----QVLASLKSSRDAKQQTLQELEQELEELGVQ 1048
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|
gi 657908800  673 LAAldrQLEQWTLPEELRLLQpsaQLEWLAQRLDELAGQRQQCQRDFDRL 722
Cdd:COG3096  1049 ADA---EAEERARIRRDELHE---ELSQNRSRRSQLEKQLTRCEAEMDSL 1092
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
316-595 1.96e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.28  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  316 KQLEQELRhseQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLR------QAQAPLREAFQLESEARRLERTLA 389
Cdd:PRK10929   26 KQITQELE---QAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNM 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  390 ERQELHRQSNQRHAQQSDAARQLDMEQQRHV----------AEQAQLQAALRD-SQALAALGDAwATHQGQlAAFVQRRQ 458
Cdd:PRK10929  103 STDALEQEILQVSSQLLEKSRQAQQEQDRAReisdslsqlpQQQTEARRQLNEiERRLQTLGTP-NTPLAQ-AQLTALQA 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  459 RALESQAQLPELEksLAQAG----EPLERLQAQwaaLHGSEPDDLAARLDELRRQTDSLERQQAlhkewQQALDQRTGLA 534
Cdd:PRK10929  181 ESAALKALVDELE--LAQLSannrQELARLRSE---LAKKRSQQLDAYLQALRNQLNSQRQREA-----ERALESTELLA 250
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657908800  535 RRLGELDQRMVEQEQALLDLKRQGSQCAE--------QVKAAEQALQV------TREllQRQRLARSSSV-EQLRA 595
Cdd:PRK10929  251 EQSGDLPKSIVAQFKINRELSQALNQQAQrmdliasqQRQAASQTLQVrqalntLRE--QSQWLGVSNALgEALRA 324
AAA_29 pfam13555
P-loop containing region of AAA domain;
26-67 2.21e-05

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 43.36  E-value: 2.21e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 657908800    26 PLSSAGLFAITGPTGAGKSTVLDALcLALFGSTPRLESTSAS 67
Cdd:pfam13555   18 PIDPRGNTLLTGPSGSGKSTLLDAI-QTLLVPAKRARFNKAA 58
COG3899 COG3899
Predicted ATPase [General function prediction only];
362-760 6.00e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 47.55  E-value: 6.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  362 DHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGD 441
Cdd:COG3899   844 GPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAA 923
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  442 AWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQW--AALHGSEPDDLAARLDELRRQTDSLERQQAL 519
Cdd:COG3899   924 AAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAalAAAAAAAAAAAAAAAAAALEAAAAALLALLA 1003
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  520 HKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVD 599
Cdd:COG3899  1004 AAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAA 1083
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  600 GEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQ 679
Cdd:COG3899  1084 AAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLL 1163
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  680 LEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEH 759
Cdd:COG3899  1164 LALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLLLLLAALALAAALLALRLL 1243

                  .
gi 657908800  760 L 760
Cdd:COG3899  1244 A 1244
mukB PRK04863
chromosome partition protein MukB;
147-867 6.72e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 6.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  147 EFREQLEQKLGLNFAQFTRAVLLAQS-----EFSAFLKASDNDRGALLEKLTDTGLYSQLSKAA---YQRASQADEQRKQ 218
Cdd:PRK04863  280 ERRVHLEEALELRRELYTSRRQLAAEqyrlvEMARELAELNEAESDLEQDYQAASDHLNLVQTAlrqQEKIERYQADLEE 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  219 LEQRLEGSLPLAEQARaglEAALESHAQARLQEQQALqRLEGQ----QQWFTEEQRLLQSCEHAQGQLAEARQAWDALAT 294
Cdd:PRK04863  360 LEERLEEQNEVVEEAD---EQQEENEARAEAAEEEVD-ELKSQladyQQALDVQQTRAIQYQQAVQALERAKQLCGLPDL 435
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  295 ERETLQ-WLERL-APVRGLIERLKQLEQELRHSeqqqRQRTEQQAAGAERLQGLQARV------QEARERQAQADDHLRQ 366
Cdd:PRK04863  436 TADNAEdWLEEFqAKEQEATEELLSLEQKLSVA----QAAHSQFEQAYQLVRKIAGEVsrseawDVARELLRRLREQRHL 511
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  367 AQaplrEAFQLESEARRLERTLAERQELHR---QSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAAlgdAW 443
Cdd:PRK04863  512 AE----QLQQLRMRLSELEQRLRQQQRAERllaEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRM---AL 584
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  444 ATHQGQLAAFVQR-RQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHgsepdDLAARLDELRRQTDSLERQQALHKE 522
Cdd:PRK04863  585 RQQLEQLQARIQRlAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQ-----QLLERERELTVERDELAARKQALDE 659
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  523 WQQALDQRTG--------LARRLG-----ELDQRMVEQEQALLDLKRQGSQCA------EQVKAAEQALQVTRELL---- 579
Cdd:PRK04863  660 EIERLSQPGGsedprlnaLAERFGgvllsEIYDDVSLEDAPYFSALYGPARHAivvpdlSDAAEQLAGLEDCPEDLylie 739
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  580 ---QRQRLARSSSVEQLRAGLVD--GEACPVCGSQEHPY---HQSEQLLAALGEHDDQEQVRAEQA------LERLRQTL 645
Cdd:PRK04863  740 gdpDSFDDSVFSVEELEKAVVVKiaDRQWRYSRFPEVPLfgrAAREKRIEQLRAEREELAERYATLsfdvqkLQRLHQAF 819
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  646 VGLREGYSS------QRERLNQSRQEQQELTGQLAALD----RQLEQWTLPEE----LRLLQPSAQL---EWLAQRLDEL 708
Cdd:PRK04863  820 SRFIGSHLAvafeadPEAELRQLNRRRVELERALADHEsqeqQQRSQLEQAKEglsaLNRLLPRLNLladETLADRVEEI 899
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  709 AGQRQQCQRDfDRLIARQRQTQQLQQELRAAetiLQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLlsDEHWQRwqadpl 788
Cdd:PRK04863  900 REQLDEAEEA-KRFVQQHGNALAQLEPIVSV---LQSDPEQFEQLKQDYQQAQQTQRDAKQQAFAL--TEVVQR------ 967
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  789 RTFQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQ-------AEERVQAELAELNGRLGAhL 861
Cdd:PRK04863  968 RAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQvlaslksSYDAKRQMLQELKQELQD-L 1046

                  ....*.
gi 657908800  862 GQHACA 867
Cdd:PRK04863 1047 GVPADS 1052
mukB PRK04863
chromosome partition protein MukB;
214-1005 6.78e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 6.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  214 EQRKQLEQRLEGSLPLAEQARAGL---------EAALEShAQARLQEQQALQRLEGQQQWFTEEQ--RLLQSCEHAQGQL 282
Cdd:PRK04863  321 EAESDLEQDYQAASDHLNLVQTALrqqekieryQADLEE-LEERLEEQNEVVEEADEQQEENEARaeAAEEEVDELKSQL 399
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  283 AEARQAWDALatERETLQWlerlapvrglierlKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADD 362
Cdd:PRK04863  400 ADYQQALDVQ--QTRAIQY--------------QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQ 463
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  363 HLRQAQAPLR---EAFQL----ESEARRLERTLAERQELHRQSNQRH-AQQSDAARQLDMEQQRHVAEQAQLQAALRDSQ 434
Cdd:PRK04863  464 KLSVAQAAHSqfeQAYQLvrkiAGEVSRSEAWDVARELLRRLREQRHlAEQLQQLRMRLSELEQRLRQQQRAERLLAEFC 543
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  435 ALAALgdawathQGQLAAFVQRRQRALEsqAQLPELEKSLAQAGEPLERLQAQwaalhgsepddlaarLDELRRQTDSLE 514
Cdd:PRK04863  544 KRLGK-------NLDDEDELEQLQEELE--ARLESLSESVSEARERRMALRQQ---------------LEQLQARIQRLA 599
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  515 RQQalhKEWQQALDQRTGLARRLGELD---QRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRqrlARSSSVE 591
Cdd:PRK04863  600 ARA---PAWLAAQDALARLREQSGEEFedsQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQ---PGGSEDP 673
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  592 QLRA------GLVDGEACPVCGSQEHPYHQseqllAALGEhddqeqvrAEQA-----LERLRQTLVGLR---------EG 651
Cdd:PRK04863  674 RLNAlaerfgGVLLSEIYDDVSLEDAPYFS-----ALYGP--------ARHAivvpdLSDAAEQLAGLEdcpedlyliEG 740
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  652 yssQRERLNQSRQEQQELTGQLA--ALDRQLEQWTLPE---------ELRLLQPSAQLEWLAQRLDELAGQRQQCQR--- 717
Cdd:PRK04863  741 ---DPDSFDDSVFSVEELEKAVVvkIADRQWRYSRFPEvplfgraarEKRIEQLRAEREELAERYATLSFDVQKLQRlhq 817
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  718 DFDRLIARQRQTQQLQQELRAAETILQQRQQALTE----------QRQRYEHLQQQVeEDSQQLRP---LLSDEHWQrwq 784
Cdd:PRK04863  818 AFSRFIGSHLAVAFEADPEAELRQLNRRRVELERAladhesqeqqQRSQLEQAKEGL-SALNRLLPrlnLLADETLA--- 893
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  785 adplRTFQALGESIEQRRQQQARLQQVEQRLQELKQ-----RCDESSWQLKQSDEQRNEARQAEERVQA-ELAELNGRLg 858
Cdd:PRK04863  894 ----DRVEEIREQLDEAEEAKRFVQQHGNALAQLEPivsvlQSDPEQFEQLKQDYQQAQQTQRDAKQQAfALTEVVQRR- 968
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  859 AHLGQHACAQDwqlslehaAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWR----ERQ 934
Cdd:PRK04863  969 AHFSYEDAAEM--------LAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRqmlqELK 1040
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657908800  935 DNLDDSRLDALLGLsEEQATQWREQL-QRLQEeiTRQQTLEAERQAQLLQHRRQRPETDREALEDNLRQQRE 1005
Cdd:PRK04863 1041 QELQDLGVPADSGA-EERARARRDELhARLSA--NRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMRE 1109
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
107-537 7.74e-05

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 46.89  E-value: 7.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  107 YRARWETRRSRDKADGALQKSQQSLQDLDTQQMLAANKKSEFREQLEQKLGLNFAQFTRAVLLAQSEFSAFLKASDNDRG 186
Cdd:COG4995    34 AAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALALAALALALLAAALALALAAAALAALALLAALL 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  187 ALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFT 266
Cdd:COG4995   114 ALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAAAAALLALALALAAAALALLALLLAALAAALAA 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  267 EEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGL 346
Cdd:COG4995   194 AAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALLALAAAAAALAAAAAALLALAAALLLLAALAAL 273
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  347 QARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQL 426
Cdd:COG4995   274 AAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLAALLLLLAALALLALLLLLAAAALLAAALAAAL 353
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  427 QAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDDLAARLDEL 506
Cdd:COG4995   354 ALAAALALALLAALLLLLAALLALLLEALLLLLLALLAALLLLAAALLALAAAQLLRLLLAALALLLALAAYAAARLALL 433
                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 657908800  507 RR-----QTDSLERQQALHKEWQQALDQRTGLARRL 537
Cdd:COG4995   434 ALieyiiLPDRLYAFVQLYQLLIAPIEAELPGIKRL 469
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
738-1061 8.18e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.98  E-value: 8.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   738 AAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHwqrwqadplRTFQALGESIEQRRQQQarlqqveQRLQE 817
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ---------LRVKEKIGELEAEIASL-------ERSIA 311
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   818 LKQRcdesswQLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLRE 897
Cdd:TIGR02169  312 EKER------ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   898 EQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLddsrldallglseeqatqwREQLQRLQEEITRQQTLEAER 977
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL-------------------NAAIAGIEAKINELEEEKEDK 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   978 QAQLlqhrrqrpetdrEALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELE---RARAEFRRWGRLNEL 1054
Cdd:TIGR02169  447 ALEI------------KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaRASEERVRGGRAVEE 514

                   ....*..
gi 657908800  1055 IGSSSGD 1061
Cdd:TIGR02169  515 VLKASIQ 521
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1-847 2.75e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 2.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAgEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLESTsasskvpdgrneLSSN 80
Cdd:PRK03918    1 MKIEELKIKNFRSHK-SSVVEFDD------GINLIIGQNGSGKSSILEAILVGLYWGHGSKPKG------------LKKD 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 DernlLRRGCASGYAEVDFVGIDGHRYRarweTRRSRDKADGALQKSQQSLQDLDTQqmlaankkSEFREQLEQKLGLNF 160
Cdd:PRK03918   62 D----FTRIGGSGTEIELKFEKNGRKYR----IVRSFNRGESYLKYLDGSEVLEEGD--------SSVREWVERLIPYHV 125
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  161 aqFTRAVLLAQSEFSAFLKaSDNDRGALLEKLTDTGLYSQlskaAYQRASqadEQRKQLEQRLEgslplaeqaragleaA 240
Cdd:PRK03918  126 --FLNAIYIRQGEIDAILE-SDESREKVVRQILGLDDYEN----AYKNLG---EVIKEIKRRIE---------------R 180
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  241 LESHAQArlqEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEarqawdalateretlqwleRLAPVRGLIERLKQLEQ 320
Cdd:PRK03918  181 LEKFIKR---TENIEELIKEKEKELEEVLREINEISSELPELRE-------------------ELEKLEKEVKELEELKE 238
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  321 ELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERqaqaddhlrqaqapLREafqLESEARRLERtLAERQELHRQSNQ 400
Cdd:PRK03918  239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKE--------------IEE---LEEKVKELKE-LKEKAEEYIKLSE 300
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  401 RHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAAlgdawathqgQLAAFVQRRQRALESQAQLPELEKSLAQAGEP 480
Cdd:PRK03918  301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE----------RLEELKKKLKELEKRLEELEERHELYEEAKAK 370
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  481 LERLQAQWAALHGSEPDDLAARLDELRRQTDSLErqqalhkewqqalDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:PRK03918  371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIE-------------EEISKITARIGELKKEIKELKKAIEELKKAKGK 437
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  561 CAeqVKAAEQALQVTRELLQRQRLARSSS----------VEQLRAGLVDGEACPVCGSQEHPYHQ-SEQLLAA---LGEH 626
Cdd:PRK03918  438 CP--VCGRELTEEHRKELLEEYTAELKRIekelkeieekERKLRKELRELEKVLKKESELIKLKElAEQLKELeekLKKY 515
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  627 DDQEQVRAEQALERLRQTLVGLRegysSQRERLNQSRQEQQELTGQLAALDRQLEqwTLPEELRLLQPS------AQLEW 700
Cdd:PRK03918  516 NLEELEKKAEEYEKLKEKLIKLK----GEIKSLKKELEKLEELKKKLAELEKKLD--ELEEELAELLKEleelgfESVEE 589
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  701 LAQRLDELagqrQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEdsqqLRPLLSDEHW 780
Cdd:PRK03918  590 LEERLKEL----EPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE----LEKKYSEEEY 661
                         810       820       830       840       850       860
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657908800  781 QRWQadplrtfqalgesiEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQ 847
Cdd:PRK03918  662 EELR--------------EEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
209-438 2.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 2.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  209 ASQADEQRKQLEQRLEgslplaeQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQScehAQGQLAEARQA 288
Cdd:COG4942    15 AAAQADAAAEAEAELE-------QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA---LEQELAALEAE 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  289 WDALATERETLQwlERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQ 368
Cdd:COG4942    85 LAELEKEIAELR--AELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  369 APLREafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAA 438
Cdd:COG4942   163 AALRA--ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
353-573 3.06e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.98  E-value: 3.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  353 ARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMeqqrHVAEQAQLQAALRD 432
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLAL----AAGEAAAAAAALLL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  433 SQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALH---GSEPDDLAARLDeLRRQ 509
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRralALNPDFAEAYLN-LGEA 155
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 657908800  510 TDSLERQQALHKEWQQALDQRTGLA---RRLGeldqrmveqeQALLDLKRQgsqcAEQVKAAEQALQ 573
Cdd:COG3914   156 LRRLGRLEEAIAALRRALELDPDNAealNNLG----------NALQDLGRL----EEAIAAYRRALE 208
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-586 3.17e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 3.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    1 MKILAIRLKNLASLAgEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLALFGstpRLESTSASSKVPDGRNELSSN 80
Cdd:COG4717     1 MKIKELEIYGFGKFR-DRTIEF------SPGLNVIYGPNEAGKSTLLAFIRAMLLE---RLEKEADELFKPQGRKPELNL 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   81 DERNLLRrgcasgyaevdfvgidghryrarwETRRSRDKADGALQKSQQSLQDLDTQQMLAANKKSEFREQLEQklgLNF 160
Cdd:COG4717    71 KELKELE------------------------EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK---LEK 123
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  161 AQFTRAVLLAQSEFSAFLKASDNDRGALLEKLTDtglYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAA 240
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERLEELEERLEE---LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  241 LESHAQARLQEQQALQRLEgqqqwfteeqrllQSCEHAQGQLAEArQAWDALATERETLQWLERLAPVRGLIERLKQLEQ 320
Cdd:COG4717   201 LEELQQRLAELEEELEEAQ-------------EELEELEEELEQL-ENELEAAALEERLKEARLLLLIAAALLALLGLGG 266
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  321 ELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQaplreafqlESEARRLERTLAERQELHRQSNQ 400
Cdd:COG4717   267 SLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE---------ELEEEELEELLAALGLPPDLSPE 337
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  401 RHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEP 480
Cdd:COG4717   338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGE 417
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  481 LERLQAQWaalhgsEPDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQ 560
Cdd:COG4717   418 LEELLEAL------DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491
                         570       580
                  ....*....|....*....|....*.
gi 657908800  561 CAEqVKAAEQALQVTRELLQRQRLAR 586
Cdd:COG4717   492 WAA-LKLALELLEEAREEYREERLPP 516
ABC_SMC_barmotin cd03278
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ...
6-54 3.32e-04

ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213245 [Multi-domain]  Cd Length: 197  Bit Score: 43.22  E-value: 3.32e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 657908800    6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLAL 54
Cdd:cd03278     4 LELKGFKSFADKTTIPFPP------GLTAIVGPNGSGKSNIIDAIRWVL 46
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
738-1043 4.43e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 4.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  738 AAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSD-----EHWQRwqadpLRTFQALGESIEQRrqqqarlqqvE 812
Cdd:COG3096   289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDyqaasDHLNL-----VQTALRQQEKIERY----------Q 353
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  813 QRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLG----AHLGQHACAQDWQ----------------- 871
Cdd:COG3096   354 EDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqqALDVQQTRAIQYQqavqalekaralcglpd 433
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  872 LSLEHAAQAAQSAVETLQAPLDSLR--EEQLRLAEA----LEHLQQQRQRQQDEFQRLQAdWQAWRERQDNLDDSRLDAl 945
Cdd:COG3096   434 LTPENAEDYLAAFRAKEQQATEEVLelEQKLSVADAarrqFEKAYELVCKIAGEVERSQA-WQTARELLRRYRSQQALA- 511
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  946 lglseEQATQWREQLQRLQEEITRQQtlEAERQAQLLQHRRQRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADN 1025
Cdd:COG3096   512 -----QRLQQLRAQLAELEQRLRQQQ--NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELR 584
                         330
                  ....*....|....*...
gi 657908800 1026 QRREQSQALLAELeRARA 1043
Cdd:COG3096   585 QQLEQLRARIKEL-AARA 601
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
449-1046 4.86e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  449 QLAAFVQRRQRAleSQAQLPeLEKSLAQAGEPLERLQAQWAalhGSEPDDLAARLDELRRQTDSLERQ-QALHKEWQQAL 527
Cdd:PRK02224  160 QLGKLEEYRERA--SDARLG-VERVLSDQRGSLDQLKAQIE---EKEEKDLHERLNGLESELAELDEEiERYEEQREQAR 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  528 DQRTGLARRLGELDQRMVE---QEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRLARSSSVEqlRAGLVDGEACP 604
Cdd:PRK02224  234 ETRDEADEVLEEHEERREEletLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLA--EAGLDDADAEA 311
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  605 VCGSQEHPYHQSEQLlaalgeHDDQEQVRaeQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAAL-----DRQ 679
Cdd:PRK02224  312 VEARREELEDRDEEL------RDRLEECR--VAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreaveDRR 383
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  680 LEQWTLPEELRLLQPS-----AQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRA---------------- 738
Cdd:PRK02224  384 EEIEELEEEIEELRERfgdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleagkcpecgqpveg 463
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  739 ---AETILQQRQQA--LTEQRQRYEHLQQQVEEDSQQLRPLLSDEHwqrwQADPLR-TFQALGESIEQRRQQQARLqqvE 812
Cdd:PRK02224  464 sphVETIEEDRERVeeLEAELEDLEEEVEEVEERLERAEDLVEAED----RIERLEeRREDLEELIAERRETIEEK---R 536
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  813 QRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNGRLGAHlgqhacaqdwqlsleHAAQAAQSAVETLQAPL 892
Cdd:PRK02224  537 ERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL---------------KERIESLERIRTLLAAI 601
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  893 DSLREEQLRLAEALEHLQQQRQRQQDefqRLQADWQAWRERQDNLDDSRLdallglseEQATQWREQLQRLQEEITRQ-Q 971
Cdd:PRK02224  602 ADAEDEIERLREKREALAELNDERRE---RLAEKRERKRELEAEFDEARI--------EEAREDKERAEEYLEQVEEKlD 670
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 657908800  972 TLEAERQAqlLQHRRQRPETDREALEDnLRQQRERLAtseqaylDTYSQLQADNQRREQSQALLAELeraRAEFR 1046
Cdd:PRK02224  671 ELREERDD--LQAEIGAVENELEELEE-LRERREALE-------NRVEALEALYDEAEELESMYGDL---RAELR 732
COG1106 COG1106
ATPase/GTPase, AAA15 family [General function prediction only];
6-117 4.87e-04

ATPase/GTPase, AAA15 family [General function prediction only];


Pssm-ID: 440723 [Multi-domain]  Cd Length: 330  Bit Score: 43.88  E-value: 4.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    6 IRLKNLASLAGEQEIDFTREPLSSAGLFAITGPTGAGKSTVLDALclalfgstprlesTSASSKVPDGRNELSSNDERNL 85
Cdd:COG1106     5 FSIENFRSFKDELTLSMVASGLRLLRVNLIYGANASGKSNLLEAL-------------YFLRNLVLNSSQPGDKLVEPFL 71
                          90       100       110
                  ....*....|....*....|....*....|....
gi 657908800   86 LRRGCASGYA--EVDFVgIDGHRYRARWETRRSR 117
Cdd:COG1106    72 LDSESKNEPSefEILFL-LDGVRYEYGFELDKER 104
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
204-441 6.07e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 6.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  204 AAYQRASQADEQRKQLEQRL---EGSLPLAEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQscehaqg 280
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIaelEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE------- 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  281 qlAEARQAWDALATERETLQWLERLAPVRGLIERLKQL-----EQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARE 355
Cdd:COG4942    90 --KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLlspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  356 RQAQADDHLRQAQAplreafQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQA 435
Cdd:COG4942   168 ELEAERAELEALLA------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241

                  ....*.
gi 657908800  436 LAALGD 441
Cdd:COG4942   242 RTPAAG 247
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
594-1169 6.31e-04

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 44.09  E-value: 6.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  594 RAGLVDGEACPVCGSQEHPYHQSEQLLAALGE-----HD-DQEQVRAEQALERlrqtlVGLReGYSSQRERLNQSRQEQQ 667
Cdd:COG3321   808 RQCLAAAGDAVVLPSLRRGEDELAQLLTALAQlwvagVPvDWSALYPGRGRRR-----VPLP-TYPFQREDAAAALLAAA 881
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  668 ELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQ 747
Cdd:COG3321   882 LAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEA 961
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  748 QALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSW 827
Cdd:COG3321   962 GALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAA 1041
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  828 QLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALE 907
Cdd:COG3321  1042 AAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALALAAAA 1121
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  908 HLQQQRQRQQDEFQRLQADWQAWRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQ 987
Cdd:COG3321  1122 AALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALL 1201
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  988 RPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRRWGRLNELIGSSSGDKFRRIA 1067
Cdd:COG3321  1202 AALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAAAAAA 1281
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800 1068 QGYNLDLLVQHSNVQLRQLARRYRLQRGGSeLGLLVVDTEMGDELRSVYSLSGGETFLISLALALGLASMASSKLRIESL 1147
Cdd:COG3321  1282 AAALALAAAAAAAAAALAALLAAAAAAAAA-AAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAA 1360
                         570       580
                  ....*....|....*....|..
gi 657908800 1148 FIDEGFGSLDPESLQLAMDALD 1169
Cdd:COG3321  1361 AALAAAAGAAAAAAALALAALA 1382
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
828-1060 6.53e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.17  E-value: 6.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  828 QLKQSDEQRNEARQAEERVQAELAELNGRLGAHLGQHACAQDWqLSLEHAAQAAQSAVETLQAPLDSL----REEQLRLA 903
Cdd:COG3096   293 ELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDH-LNLVQTALRQQEKIERYQEDLEELterlEEQEEVVE 371
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  904 EALEHLQQQRQRQQ---DEFQRLQ---ADWQ-----------AWRERQDNLDDSR-LDALLGLSEEQATQWREQLQRLQE 965
Cdd:COG3096   372 EAAEQLAEAEARLEaaeEEVDSLKsqlADYQqaldvqqtraiQYQQAVQALEKARaLCGLPDLTPENAEDYLAAFRAKEQ 451
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  966 EITrQQTLEAERQAQLLQHRRQRPETDREALEdNLRQQRERLATSEQA--YLDTYSQLQADNQRREQSQALLAELERARA 1043
Cdd:COG3096   452 QAT-EEVLELEQKLSVADAARRQFEKAYELVC-KIAGEVERSQAWQTAreLLRRYRSQQALAQRLQQLRAQLAELEQRLR 529
                         250
                  ....*....|....*..
gi 657908800 1044 EFRRWGRLNELIGSSSG 1060
Cdd:COG3096   530 QQQNAERLLEEFCQRIG 546
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
6-1047 6.85e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800     6 IRLKNLASLAGEQEIDFTReplssaGLFAITGPTGAGKSTVLDALCLALFgstprlESTSASSKVPDGRNELSSNDERNL 85
Cdd:pfam02463    5 IEIEGFKSYAKTVILPFSP------GFTAIVGPNGSGKSNILDAILFVLG------ERSAKSLRSERLSDLIHSKSGAFV 72
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    86 LrrgcaSGYAEVDFVGIDGHRYRARWETRRSRDKAdgalqKSQQSLQDLDTQQMLAANKKSEFREQLEQKLGLNFaqftr 165
Cdd:pfam02463   73 N-----SAEVEITFDNEDHELPIDKEEVSIRRRVY-----RGGDSEYYINGKNVTKKEVAELLESQGISPEAYNF----- 137
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   166 avLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQ----RASQADEQRKQLEQRLEgSLPLAEQARAGLeaal 241
Cdd:pfam02463  138 --LVQGGKIEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKlieeTENLAELIIDLEELKLQ-ELKLKEQAKKAL---- 210
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   242 eshaqaRLQEQQALQRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETlqwlerlapvrgLIERLKQLEQE 321
Cdd:pfam02463  211 ------EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE------------KEEEKLAQVLK 272
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   322 LRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDhlrqaqaplREAFQLESEARRLERTLAERQELhrQSNQR 401
Cdd:pfam02463  273 ENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE---------EKLKESEKEKKKAEKELKKEKEE--IEELE 341
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   402 HAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPL 481
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   482 ERLQAQWAALHGSEPDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQ- 560
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQk 501
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   561 --CAEQVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQ---SEQLLAALGEHDDQEQVRAE 635
Cdd:pfam02463  502 esKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADeveERQKLVRALTELPLGARKLR 581
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   636 QALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAA-------LDRQLEQWTLPEELRLLQPSAQLEWLAQRLDEL 708
Cdd:pfam02463  582 LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRakvvegiLKDTELTKLKESAKAKESGLRKGVSLEEGLAEK 661
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   709 AGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPL 788
Cdd:pfam02463  662 SEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL 741
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   789 RTFQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAELNgrlgAHLGQHACAQ 868
Cdd:pfam02463  742 KQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE----EELKEEAELL 817
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   869 DWQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADwQAWRERQDNLDDSRLDALLGL 948
Cdd:pfam02463  818 EEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK-EEELEEQKLKDELESKEEKEK 896
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   949 SEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDR-------EALEDNLRQQRERLATSEQAY------- 1014
Cdd:pfam02463  897 EEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLleeadekEKEENNKEEEEERNKRLLLAKeelgkvn 976
                         1050      1060      1070
                   ....*....|....*....|....*....|...
gi 657908800  1015 LDTYSQLQADNQRREQSQALLAELERARAEFRR 1047
Cdd:pfam02463  977 LMAIEEFEEKEERYNKDELEKERLEEEKKKLIR 1009
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
1113-1183 9.38e-04

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 42.07  E-value: 9.38e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657908800 1113 RSVYSLSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:cd03225   130 RSPFTLSGGQKQRVAIAGVL----AMDPDI----LLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTH 192
ABC_RecN cd03241
ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC ...
6-56 1.06e-03

ATP-binding cassette domain of RecN; RecN ATPase involved in DNA repair; similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213208 [Multi-domain]  Cd Length: 276  Bit Score: 42.57  E-value: 1.06e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 657908800    6 IRLKNLAsLAGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALcLALFG 56
Cdd:cd03241     4 LSIKNFA-LIEELELDF------EEGLTVLTGETGAGKSILLDAL-SLLLG 46
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
365-758 1.09e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  365 RQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDmEQQRHVAEQAQLQAALRDSQALAALGDAWA 444
Cdd:COG4717    64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELE-ELREELEKLEKLLQLLPLYQELEALEAELA 142
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  445 THQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDDLAARLDELRRQTDSLERQQALHKEWQ 524
Cdd:COG4717   143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  525 QALDQRTGLARRLGELDQRMVEQEQALLDLK----------------------------RQGSQCAEQVKAAEQALQVTR 576
Cdd:COG4717   223 EELEEELEQLENELEAAALEERLKEARLLLLiaaallallglggsllsliltiagvlflVLGLLALLFLLLAREKASLGK 302
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  577 ELLQRQRLARSSSVEQLR-AGLVDGEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQ 655
Cdd:COG4717   303 EAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVE 382
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  656 -----RERLNQSrQEQQELTGQLAALDRQLEQwtLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRL---IARQR 727
Cdd:COG4717   383 deeelRAALEQA-EEYQELKEELEELEEQLEE--LLGELEELLEALDEEELEEELEELEEELEELEEELEELreeLAELE 459
                         410       420       430
                  ....*....|....*....|....*....|.
gi 657908800  728 QTQQLQQELRAAETILQQRQQALTEQRQRYE 758
Cdd:COG4717   460 AELEQLEEDGELAELLQELEELKAELRELAE 490
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
230-432 1.22e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  230 AEQARAGLEAALESHAQARLQEQQALQRLEGQQQWFTEEQRLLQSCEhaqgQLAEARQAWDALATERETLQwlERLAPVR 309
Cdd:COG4913   608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA----EYSWDEIDVASAEREIAELE--AELERLD 681
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  310 GLIERLKQLEQELRhseqqqrQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLErtLA 389
Cdd:COG4913   682 ASSDDLAALEEQLE-------ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LE 752
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 657908800  390 ERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRD 432
Cdd:COG4913   753 ERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
309-1040 1.22e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.40  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  309 RGLIERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQLE---SEARRLE 385
Cdd:COG3096   281 RELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIEryqEDLEELT 360
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  386 RTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALrdsqalaalgDAWATHQGQLAAFVQRRQRAlESQA 465
Cdd:COG3096   361 ERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAL----------DVQQTRAIQYQQAVQALEKA-RALC 429
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  466 QLPELekSLAQAGEPLERLQAQWAALHG---------SEPDDLAARLDE----LRRQTDSLERQQAL---------HKEW 523
Cdd:COG3096   430 GLPDL--TPENAEDYLAAFRAKEQQATEevleleqklSVADAARRQFEKayelVCKIAGEVERSQAWqtarellrrYRSQ 507
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  524 QQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQalqvTRELLQRQRLARSSSVEQLRAGLVDGEAC 603
Cdd:COG3096   508 QALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEE----LEELLAELEAQLEELEEQAAEAVEQRSEL 583
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  604 pvcgsqehpYHQSEQLLAALGEHDDQEQV--RAEQALERLRQ-------TLVGLREGYSSQRERLNQSRQEQQELTGQLA 674
Cdd:COG3096   584 ---------RQQLEQLRARIKELAARAPAwlAAQDALERLREqsgealaDSQEVTAAMQQLLEREREATVERDELAARKQ 654
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  675 ALDRQLEqwtlpeelRLLQPS----AQLEWLAQRL---------------------------------DELAGQRQQ--- 714
Cdd:COG3096   655 ALESQIE--------RLSQPGgaedPRLLALAERLggvllseiyddvtledapyfsalygparhaivvPDLSAVKEQlag 726
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  715 ----------CQRDFDrliARQRQTQQLQQELRAAETILQQRQQALTE-----------QRQRYEHLQQQVEEDSQQLRP 773
Cdd:COG3096   727 ledcpedlylIEGDPD---SFDDSVFDAEELEDAVVVKLSDRQWRYSRfpevplfgraaREKRLEELRAERDELAEQYAK 803
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  774 LLSDEhwQRWQadplRTFQALGESIeQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERVQAELAEL 853
Cdd:COG3096   804 ASFDV--QKLQ----RLHQAFSQFV-GGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLL 876
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  854 NGRLG-AHLgqhacaqdwqLSLEHAAQAAQSAVETLQAPLDSLREEQL--RLAEALEHLQQQRQRQQDEFQRLQADWQAW 930
Cdd:COG3096   877 NKLLPqANL----------LADETLADRLEELREELDAAQEAQAFIQQhgKALAQLEPLVAVLQSDPEQFEQLQADYLQA 946
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  931 RERQDNLDdSRLDALlglseEQATQWREQL--QRLQEEITRQQTLEAERQAQLLQHRRQRpetdrealednlRQQRERLA 1008
Cdd:COG3096   947 KEQQRRLK-QQIFAL-----SEVVQRRPHFsyEDAVGLLGENSDLNEKLRARLEQAEEAR------------REAREQLR 1008
                         810       820       830
                  ....*....|....*....|....*....|..
gi 657908800 1009 TSEQAYLDTYSQLQADNQRREQSQALLAELER 1040
Cdd:COG3096  1009 QAQAQYSQYNQVLASLKSSRDAKQQTLQELEQ 1040
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
1-54 1.39e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 42.30  E-value: 1.39e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 657908800    1 MKILAIRLKNLASLaGEQEIDFtreplsSAGLFAITGPTGAGKSTVLDALCLAL 54
Cdd:COG3593     1 MKLEKIKIKNFRSI-KDLSIEL------SDDLTVLVGENNSGKSSILEALRLLL 47
COG3903 COG3903
Predicted ATPase [General function prediction only];
257-642 1.76e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 42.70  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  257 RLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQRTEQQ 336
Cdd:COG3903   546 RLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLL 625
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  337 AAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQ 416
Cdd:COG3903   626 LAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAA 705
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  417 QRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEP 496
Cdd:COG3903   706 AAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAA 785
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  497 DDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTR 576
Cdd:COG3903   786 LAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAA 865
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657908800  577 ELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLR 642
Cdd:COG3903   866 AAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAA 931
Ras_like_GTPase cd00882
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like ...
34-124 2.01e-03

Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.


Pssm-ID: 206648 [Multi-domain]  Cd Length: 161  Bit Score: 40.13  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   34 AITGPTGAGKSTVLDALCLALFGSTPRLESTSASSKVpdGRNELSSNDERNLLrrgcasgyaeVDFVGI-DGHRYRARWE 112
Cdd:cd00882     1 VVVGRGGVGKSSLLNALLGGEVGEVSDVPGTTRDPDV--YVKELDKGKVKLVL----------VDTPGLdEFGGLGREEL 68
                          90
                  ....*....|..
gi 657908800  113 TRRSRDKADGAL 124
Cdd:cd00882    69 ARLLLRGADLIL 80
PTZ00121 PTZ00121
MAEBL; Provisional
500-1044 2.52e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 2.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  500 AARLDELRRQTDSLERQQALHKEwqqaLDQRTGLARRLGelDQRMVEQEQALLDLKR-QGSQCAEQVKAAEQALQV--TR 576
Cdd:PTZ00121 1127 ARKAEEARKAEDARKAEEARKAE----DAKRVEIARKAE--DARKAEEARKAEDAKKaEAARKAEEVRKAEELRKAedAR 1200
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  577 ELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLLAalgehddqEQVRAEQALERLRQTlvglREGYSSQR 656
Cdd:PTZ00121 1201 KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA--------EEERNNEEIRKFEEA----RMAHFARR 1268
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  657 ERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLI-----------AR 725
Cdd:PTZ00121 1269 QAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKkkaeeakkaaeAA 1348
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  726 QRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRwQADPLRTFQALGESIEQRRQQQ 805
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK-KADELKKAAAAKKKADEAKKKA 1427
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  806 ARLQQVEQ---------RLQELKQRCDES--SWQLKQSDEQRNEA----RQAEERVQAE----LAELNGRLGAHLGQHAC 866
Cdd:PTZ00121 1428 EEKKKADEakkkaeeakKADEAKKKAEEAkkAEEAKKKAEEAKKAdeakKKAEEAKKADeakkKAEEAKKKADEAKKAAE 1507
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  867 AQDWQLSLEHA-----AQAAQSAVETLQAplDSLRE-------EQLRLAEAL---EHLQQQRQRQQDEFQRLQADWQAWR 931
Cdd:PTZ00121 1508 AKKKADEAKKAeeakkADEAKKAEEAKKA--DEAKKaeekkkaDELKKAEELkkaEEKKKAEEAKKAEEDKNMALRKAEE 1585
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  932 ERQdnLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTL--EAERQAQLLQHRRQRPETDREALEDNLRQQRERLAT 1009
Cdd:PTZ00121 1586 AKK--AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA 1663
                         570       580       590
                  ....*....|....*....|....*....|....*
gi 657908800 1010 SEQAYLDTYSQLQADNQRREQSQALLAELERARAE 1044
Cdd:PTZ00121 1664 AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698
EntF COG1020
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ...
444-860 2.88e-03

EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440643 [Multi-domain]  Cd Length: 1329  Bit Score: 42.15  E-value: 2.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  444 ATHQGQLAAF-VQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDDLAARLDELRRQTDSLERQQALHKE 522
Cdd:COG1020   909 APGDKRLVAYvVPEAGAAAAAALLRLALALLLPPYMVPAAVVLLLPLPLTGNGKLDRLALPAPAAAAAAAAAAPPAEEEE 988
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  523 WQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQ---ALQVTRELLQRQRLARSSSVEQLRAGLVD 599
Cdd:COG1020   989 EEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLALARAARLLLLLLLLlllFLAAAAAAAAAAAAAAAAAAAAPLAAAAA 1068
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  600 GEACPVCGSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQ 679
Cdd:COG1020  1069 PLPLPPLLLSLLALLLALLLLLALLALLALLLLLLLLLLLLALLLLLALLLALLAALRARRAVRQEGPRLRLLVALAAAL 1148
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  680 LEQWTLPEELRLLQPSAQLEWLAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEH 759
Cdd:COG1020  1149 ALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLAAAA 1228
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  760 LQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQVEQRLQELKQRCDESSWQLKQSDEQRNEA 839
Cdd:COG1020  1229 AALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARAARTARALALLLLLALLLLLA 1308
                         410       420
                  ....*....|....*....|.
gi 657908800  840 RQAEERVQAELAELNGRLGAH 860
Cdd:COG1020  1309 LALALLLLLLLLLALLLLALL 1329
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
1118-1191 2.98e-03

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 40.07  E-value: 2.98e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657908800 1118 LSGGETFLISLALALglasMASSKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQEMHERI 1191
Cdd:cd03230    96 LSGGMKQRLALAQAL----LHDPEL----LILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERL 161
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
166-411 3.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 3.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  166 AVLLAQSEFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQRLEGSLPLAEQARAGLEAALESHA 245
Cdd:COG4942     7 LALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  246 QARLQEQQALQRLEGQQQWFTEEQRLLQScEHAQGQLAEARQAWDALATEReTLQWLERLAPVR-GLIERLKQLEQELRH 324
Cdd:COG4942    87 ELEKEIAELRAELEAQKEELAELLRALYR-LGRQPPLALLLSPEDFLDAVR-RLQYLKYLAPARrEQAEELRADLAELAA 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  325 SEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLR-EAFQLESEARRLERTLAERQELHRQSNQRHA 403
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAaELAELQQEAEELEALIARLEAEAAAAAERTP 244

                  ....*...
gi 657908800  404 QQSDAARQ 411
Cdd:COG4942   245 AAGFAALK 252
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
252-709 3.44e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 3.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  252 QQALQRLEGQQQWFTEEQRLLQSCEHaqgQLAEARQAWDALATERETLQWLERLAPVRGLIERLKQLEQELRHSEQQQRQ 331
Cdd:COG4717    77 EEELKEAEEKEEEYAELQEELEELEE---ELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEE 153
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  332 RTEQQAAGAERLQGLQARVQEARERQAQAddhlrQAQAPLREAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQ 411
Cdd:COG4717   154 RLEELRELEEELEELEAELAELQEELEEL-----LEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  412 LDMEQQRHVAEQAQLQAALRDSQALAAlgdawathqGQLAAFVQRRQRALESQAQLPELEKSLAQAGEPLERLQAQWAAL 491
Cdd:COG4717   229 LEQLENELEAAALEERLKEARLLLLIA---------AALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  492 HGSEPDDLAARLDELRRQTDSLERQ-QALHKEWQQALDQRTGLARRLGELDQRMVEQEQALLDLKRQGSQcAEQVKAAEQ 570
Cdd:COG4717   300 LGKEAEELQALPALEELEEEELEELlAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE-QEIAALLAE 378
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  571 ALQVTRELLqRQRLARSSSVEQLRAglvdgeacpvcgsqehpyhQSEQLLAALGEHDDQEQVRAEQAlerlrqTLVGLRE 650
Cdd:COG4717   379 AGVEDEEEL-RAALEQAEEYQELKE-------------------ELEELEEQLEELLGELEELLEAL------DEEELEE 432
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 657908800  651 GYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQpsAQLEWLAQRLDELA 709
Cdd:COG4717   433 ELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELL--QELEELKAELRELA 489
ABC_SMC5_euk cd03277
ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of ...
3-97 4.53e-03

ATP-binding cassette domain of eukaryotic SMC5 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213244 [Multi-domain]  Cd Length: 213  Bit Score: 39.89  E-value: 4.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800    3 ILAIRLKNLASLAgeqEIDFTREPlssaGLFAITGPTGAGKSTVLDALCLALFGSTPRLestsasskvpdGRnelsSNDE 82
Cdd:cd03277     3 IVRIKLENFVTYD---ETEFRPGP----SLNMIIGPNGSGKSSIVCAICLGLGGKPKLL-----------GR----AKKV 60
                          90
                  ....*....|....*
gi 657908800   83 RNLLRRGCASGYAEV 97
Cdd:cd03277    61 GEFVKRGCDEGTIEI 75
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
34-705 4.59e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.48  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   34 AITGPTGAGKSTVLDALCLAL--------FGSTPRLESTSASS-KVPDGRnelssndernlLRRGCAsgYAEVDFVGIDG 104
Cdd:COG3096    30 TLSGGNGAGKSTTMAAFVTALipdltllhFRNTTEAGATSGSRdKGLHGK-----------LKPGVC--YAALDVVNSRG 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  105 HRYRA--RWETRRSRDKADG----ALQ--KSQQSLQDLDTQQMLAANKK----SEFREQLEQKLGLNFAQFTRAvllaqS 172
Cdd:COG3096    97 QRLLVgvRLQQVAGRDKKVDikpfIIQglPEDVKPTDLLTETLDGRQARvlplNELKEKAEELEGVQFKQFNSI-----T 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  173 EFSAFLkasdNDRGALLEKLTDtglysqlskaayqrasqaDEQRKQLEQRLEGSLplaeqaRAGLEAALESHAQARLQEQ 252
Cdd:COG3096   172 DYHAFM----FDLGVTPKRLRS------------------SSDRSKFYRLIEASL------YGGISSAITRSLRDYLLPE 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  253 -----QALQRLEG---QQQWFTEEQRLLQSCEHAQGQLAEARQAWDALAteretlqWLERLAPVRGLIERLKQLEQELRH 324
Cdd:COG3096   224 nsgvrKAFQDMEAalrENRMTLEAIRVTQSDRDLFKHLITEATNYVAAD-------YMRHANERRELSERALELRRELFG 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  325 SEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREAFQLE---SEARRLERTLAERQELHRQSNQR 401
Cdd:COG3096   297 ARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIEryqEDLEELTERLEEQEEVVEEAAEQ 376
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  402 HAQQSDAARQLDMEQQRHVAEQAQLQAALrdsqalaalgDAWATHQGQLAAFVQRRQRAlESQAQLPELekSLAQAGEPL 481
Cdd:COG3096   377 LAEAEARLEAAEEEVDSLKSQLADYQQAL----------DVQQTRAIQYQQAVQALEKA-RALCGLPDL--TPENAEDYL 443
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  482 ERLQAQWAALHG---------SEPDDLAARLDE----LRRQTDSLERQQAL---------HKEWQQALDQRTGLARRLGE 539
Cdd:COG3096   444 AAFRAKEQQATEevleleqklSVADAARRQFEKayelVCKIAGEVERSQAWqtarellrrYRSQQALAQRLQQLRAQLAE 523
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  540 LDQRMVEQEQALLDLKRQGSQCAEQVKAAEQalqvTRELLQRQRLARSSSVEQLRAGLVDGEACpvcgsqehpYHQSEQL 619
Cdd:COG3096   524 LEQRLRQQQNAERLLEEFCQRIGQQLDAAEE----LEELLAELEAQLEELEEQAAEAVEQRSEL---------RQQLEQL 590
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  620 LAALGEHDDQEQV--RAEQALERLRQ-------TLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEqwtlpeelR 690
Cdd:COG3096   591 RARIKELAARAPAwlAAQDALERLREqsgealaDSQEVTAAMQQLLEREREATVERDELAARKQALESQIE--------R 662
                         730
                  ....*....|....*....
gi 657908800  691 LLQPS----AQLEWLAQRL 705
Cdd:COG3096   663 LSQPGgaedPRLLALAERL 681
KpsE COG3524
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
895-1047 5.41e-03

Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442746 [Multi-domain]  Cd Length: 370  Bit Score: 40.60  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  895 LREEQLRLAEAlehlqqQRQRQQDEFQRLQADWQAWRERQDNLDdsrldallglSEEQATQWREQLQRLQEEITRqqtLE 974
Cdd:COG3524   174 AREDAVRFAEE------EVERAEERLRDAREALLAFRNRNGILD----------PEATAEALLQLIATLEGQLAE---LE 234
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  975 AERQAQLLQHRRQRP-----ETDREALEDNLRQQRERLA--TSEQAY---LDTYSQLQADNQRREQS-QALLAELERARA 1043
Cdd:COG3524   235 AELAALRSYLSPNSPqvrqlRRRIAALEKQIAAERARLTgaSGGDSLaslLAEYERLELEREFAEKAyTSALAALEQARI 314

                  ....
gi 657908800 1044 EFRR 1047
Cdd:COG3524   315 EAAR 318
COG3903 COG3903
Predicted ATPase [General function prediction only];
381-749 5.77e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443109 [Multi-domain]  Cd Length: 933  Bit Score: 41.16  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  381 ARRLERTLAERQELHRQSNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALRDSQALAALGDAWATHQGQLAAFVQRRQRA 460
Cdd:COG3903   565 RRWLERALAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAA 644
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  461 LESQAQLPELEKSLAQAGEPLERLQAQWAALHGSEPDDLAARLDELRRQTDSLERQQALHKEWQQALDQRTGLARRLGEL 540
Cdd:COG3903   645 AAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAA 724
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  541 DQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVDGEACPVCGSQEHPYHQSEQLL 620
Cdd:COG3903   725 AALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAA 804
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  621 AALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEQWTLPEELRLLQPSAQLEW 700
Cdd:COG3903   805 AAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAAL 884
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 657908800  701 LAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQA 749
Cdd:COG3903   885 LAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAAA 933
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
313-516 6.30e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  313 ERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARVQEARERQAQADDHLRQAQAPLREafqLESEARRLERTLAERQ 392
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE---LEKEIAELRAELEAQK 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  393 ELHRQ---SNQRHAQQSDAARQLDMEQQRHVAEQAQLQAALrdSQALAALGDAWATHQGQLAafvQRRQRALESQAQLPE 469
Cdd:COG4942   104 EELAEllrALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL--APARREQAEELRADLAELA---ALRAELEAERAELEA 178
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 657908800  470 LEKSLAQAGEPLERLQAQWAALHGSEPDDLA---ARLDELRRQTDSLERQ 516
Cdd:COG4942   179 LLAELEEERAALEALKAERQKLLARLEKELAelaAELAELQQEAEELEAL 228
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
1113-1186 6.35e-03

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 40.22  E-value: 6.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 657908800 1113 RSVYSLSGGETFLISLALALGLASmassklriESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISHVQE 1186
Cdd:PRK13631  172 RSPFGLSGGQKRRVAIAGILAIQP--------EILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTME 237
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
1113-1183 6.41e-03

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 39.62  E-value: 6.41e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657908800 1113 RSVYSLSGGETFLISLALALglaSMASsklriESLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:COG1122   130 RPPHELSGGQKQRVAIAGVL---AMEP-----EVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTH 192
ABC_SMC4_euk cd03274
ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of ...
3-56 6.74e-03

ATP-binding cassette domain of eukaryotic SMC4 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213241 [Multi-domain]  Cd Length: 212  Bit Score: 39.59  E-value: 6.74e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 657908800    3 ILAIRLKNLASLAGEQEI-----DFTreplssaglfAITGPTGAGKSTVLDALcLALFG 56
Cdd:cd03274     3 ITKLVLENFKSYAGEQVIgpfhkSFS----------AIVGPNGSGKSNVIDSM-LFVFG 50
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
18-55 6.88e-03

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 38.77  E-value: 6.88e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 657908800   18 QEIDFTrepLSSAGLFAITGPTGAGKSTVLDALCLALF 55
Cdd:cd00267    16 DNVSLT---LKAGEIVALVGPNGSGKSTLLRAIAGLLK 50
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
448-1048 7.28e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 40.59  E-value: 7.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   448 GQLAAFVQRRQRALESQAQLPELEKsLAQAGEPLERLQAQWAALHGsepddlaARLDELRRQTDSLERQQALHKEWQQAL 527
Cdd:pfam12128  221 QQVEHWIRDIQAIAGIMKIRPEFTK-LQQEFNTLESAELRLSHLHF-------GYKSDETLIASRQEERQETSAELNQLL 292
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   528 DQRTG-LARRLGELDQRMVEQEQALLDLKRQGSQCAEQVKAAEQALQVTRELLQRQRLARSSSVEQLRAGLVDGEacpvc 606
Cdd:pfam12128  293 RTLDDqWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALT----- 367
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   607 GSQEHPYHQSEQLLAALGEHDDQEQVRAEQALERLRQTLVGLREGYSSQRERLNQSRQEQQElTGQLAALDRQLEQWTLP 686
Cdd:pfam12128  368 GKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE-AGKLEFNEEEYRLKSRL 446
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   687 EELRLLQPSAQLEwlAQRLDELAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEE 766
Cdd:pfam12128  447 GELKLRLNQATAT--PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDE 524
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   767 DSQQLRPLL-SDEHWQRWQADPLRtfQALGESIEQRRQQQARLQQV---EQRLQELK--------QRCDESSWqLKQSDE 834
Cdd:pfam12128  525 LELQLFPQAgTLLHFLRKEAPDWE--QSIGKVISPELLHRTDLDPEvwdGSVGGELNlygvkldlKRIDVPEW-AASEEE 601
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   835 QRNEARQAEERVQAElAELNGRLGAHLGQHACAQD-WQLSLEHAAQAAQSAVETLQAPLDSLREEQLRLAEALEHlqqqr 913
Cdd:pfam12128  602 LRERLDKAEEALQSA-REKQAAAEEQLVQANGELEkASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAE----- 675
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800   914 qrqqdefqrlqadwqawRERQDNLDDSRLDALLGLSEEQATQWREQLQRLQEEITRQ-----QTLEAERQAQL--LQHRR 986
Cdd:pfam12128  676 -----------------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEkqaywQVVEGALDAQLalLKAAI 738
                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 657908800   987 QRPETDREALEDNLRQQRERLATSEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRRW 1048
Cdd:pfam12128  739 AARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDW 800
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
626-1002 7.89e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 40.71  E-value: 7.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  626 HDDQEQVRAEQALErLRQTLVGLREGYSSQRERLNQSRQEQQELTGQLAALDRQLEqwTLPEELRLLQPSAQ-------- 697
Cdd:COG3096   276 HANERRELSERALE-LRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQ--AASDHLNLVQTALRqqekiery 352
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  698 ---LEWLAQRLDELAGQRQQCQrdfDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVE--EDSQQL- 771
Cdd:COG3096   353 qedLEELTERLEEQEEVVEEAA---EQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQalEKARALc 429
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  772 -RPLLSDEHWQRWQAdplrTFQAlgesieqrrqqqaRLQQVEQRLQELKQRcdesswqLKQSDEQRNEARQAEERVQAEL 850
Cdd:COG3096   430 gLPDLTPENAEDYLA----AFRA-------------KEQQATEEVLELEQK-------LSVADAARRQFEKAYELVCKIA 485
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  851 AELNgRLGAHLGQHACAQDWQlslEHAAQAAQsaVETLQAPLDSLR------EEQLRLAEALEHLQQQRQRQQDEFQRLQ 924
Cdd:COG3096   486 GEVE-RSQAWQTARELLRRYR---SQQALAQR--LQQLRAQLAELEqrlrqqQNAERLLEEFCQRIGQQLDAAEELEELL 559
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  925 ADWQAWRER-QDNLDDSR---------LDALLGLSEE---QATQWR---EQLQRLQEEI------------TRQQTLEAE 976
Cdd:COG3096   560 AELEAQLEElEEQAAEAVeqrselrqqLEQLRARIKElaaRAPAWLaaqDALERLREQSgealadsqevtaAMQQLLERE 639
                         410       420
                  ....*....|....*....|....*.
gi 657908800  977 RQAQLLqhrRQRPETDREALEDNLRQ 1002
Cdd:COG3096   640 REATVE---RDELAARKQALESQIER 662
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
1113-1183 7.95e-03

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 39.05  E-value: 7.95e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 657908800 1113 RSVYSLSGGETFLISLALALglASMAssKLriesLFIDEGFGSLDPESLQLAMDALDNLQAQGRKVAVISH 1183
Cdd:cd03235   128 RQIGELSGGQQQRVLLARAL--VQDP--DL----LLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTH 190
PRK11281 PRK11281
mechanosensitive channel MscK;
484-778 8.08e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 40.67  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  484 LQAQWAALHGSEP----DDLAARLDELRRQTDSLERQQALHKEWQQALDQrtglarrlgeLDQRMvEQEQALLDLKRQGS 559
Cdd:PRK11281   22 LSSAFARAASNGDlpteADVQAQLDALNKQKLLEAEDKLVQQDLEQTLAL----------LDKID-RQKEETEQLKQQLA 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  560 QCAEQVKAAEQALQVTRELLQ---RQRLArSSSVEQLRAGLVDGEAcpvcgsqehpyhQSEQLLAALGEHDDQ------- 629
Cdd:PRK11281   91 QAPAKLRQAQAELEALKDDNDeetRETLS-TLSLRQLESRLAQTLD------------QLQNAQNDLAEYNSQlvslqtq 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 657908800  630 -EQVRAE-----QALERLRQTLVGLREGyssqRERLNQSRQEQqeLTGQLAALDRQLEQwtlpeELRLLQPSAQLEWLAQ 703
Cdd:PRK11281  158 pERAQAAlyansQRLQQIRNLLKGGKVG----GKALRPSQRVL--LQAEQALLNAQNDL-----QRKSLEGNTQLQDLLQ 226
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 657908800  704 -RLDELAGQRQQCQrdfdrliarqrqtqqlqQELRAAETILQQRQQALTEqrQRYEHLQQQVEEDSQQLRPLLSDE 778
Cdd:PRK11281  227 kQRDYLTARIQRLE-----------------HQLQLLQEAINSKRLTLSE--KTVQEAQSQDEAARIQANPLVAQE 283
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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