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Conserved domains on  [gi|648465774|ref|WP_026157525|]
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carbohydrate ABC transporter permease [Rhizobium leguminosarum]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.25e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 296.24  E-value: 1.25e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  18 TKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSST-SLIPSSIDFSSYARGWVglDVSFGRFFWNSLVISL 96
Cdd:COG0395    7 RRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  97 LVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMV 176
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 177 QFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVdSTSA 256
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQ-GQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 648465774 257 SDWGGLFAMSTLTLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.25e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 296.24  E-value: 1.25e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  18 TKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSST-SLIPSSIDFSSYARGWVglDVSFGRFFWNSLVISL 96
Cdd:COG0395    7 RRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  97 LVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMV 176
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 177 QFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVdSTSA 256
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQ-GQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 648465774 257 SDWGGLFAMSTLTLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
29-288 2.69e-32

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 120.61  E-value: 2.69e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  29 HALLIAASLLMLYPLLWMVSASVRPENEIFSS-TSLIPSSIDFSSYARGWV----GLDVSFGRFFWNSLVISLLVVTGNV 103
Cdd:PRK10973  13 HTMLILGIAVILFPLYVAFVAATLDKQAVFAVpMTLIPGTHLLENIANIWVngvgNNSAPFGRMLLNSFVMAFSITVGKI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 104 IACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPkfLASDAFFIFLMVQFFRGIP 183
Cdd:PRK10973  93 TVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLP--LMASATATFLFRQFFMTLP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 184 RELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVDST-SASDWGGL 262
Cdd:PRK10973 171 DELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGeGTTEWNQV 250

                        250       260
                 ....*....|....*....|....*.
gi 648465774 263 FAMSTLTLVPVFFFFLFFQRLLIEGI 288
Cdd:PRK10973 251 MAAMLLTLIPPVVIVLAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-273 2.51e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 72.70  E-value: 2.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  88 FWNSLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLAS 167
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 168 DAFFIFLMVQFFRG----IPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNdMNTYTI 243
Cdd:cd06261   81 LLLIAPFARLIRRAalesIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG-GEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 648465774 244 QLGLRTFVDSTSASDWGGLFAMSTLTLVPV 273
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-271 4.78e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 4.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  108 LTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMVQFFRGIPRELD 187
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  188 EAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLND--MNTYTIQLGLRTFVDSTSASDWGGLFAM 265
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpgLGLLLIEAILGYDYPEIQGPVLAAALIL 163


                  ....*.
gi 648465774  266 STLTLV 271
Cdd:pfam00528 164 LLLNLL 169
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 24-233 2.05e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.66  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774   24 ASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSSTSlipssiDFSSYARgwvglDVSFGRFFWNSLVISLLVVTGNV 103
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFIGLA------NFAEYFA-----TPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  104 IACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLV----VPKFLASDAFFIF-----L 174
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFsiygFWGIVIGEVFYTFphalmI 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 648465774  175 MVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLI 233
Cdd:TIGR03262 152 LVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-294 1.25e-100

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 296.24  E-value: 1.25e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  18 TKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSST-SLIPSSIDFSSYARGWVglDVSFGRFFWNSLVISL 96
Cdd:COG0395    7 RRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPpSLLPSEFTLENYRAAFT--DGPFGRYLLNSLIVAV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  97 LVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMV 176
Cdd:COG0395   85 VSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPFGIFLLR 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 177 QFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVdSTSA 256
Cdd:COG0395  165 QFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQ-GQYG 243

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 648465774 257 SDWGGLFAMSTLTLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG0395  244 TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 18-294 9.16e-65

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 204.61  E-value: 9.16e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  18 TKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSStSLIPSSIDFSSYArgWVGLDVSFGRFFWNSLVISLL 97
Cdd:COG3833    8 KRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSS-SLIPENFTLENYK--KLFTETPFLRWFLNSLIVAVV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  98 VVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMVQ 177
Cdd:COG3833   85 TAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNTWLMKG 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 178 FFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVDSTSAS 257
Cdd:COG3833  165 YFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVSDQRNT 244

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 648465774 258 DWGGLFAMSTLTLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:COG3833  245 NWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
29-288 2.69e-32

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 120.61  E-value: 2.69e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  29 HALLIAASLLMLYPLLWMVSASVRPENEIFSS-TSLIPSSIDFSSYARGWV----GLDVSFGRFFWNSLVISLLVVTGNV 103
Cdd:PRK10973  13 HTMLILGIAVILFPLYVAFVAATLDKQAVFAVpMTLIPGTHLLENIANIWVngvgNNSAPFGRMLLNSFVMAFSITVGKI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 104 IACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPkfLASDAFFIFLMVQFFRGIP 183
Cdd:PRK10973  93 TVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLP--LMASATATFLFRQFFMTLP 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 184 RELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGLRTFVDST-SASDWGGL 262
Cdd:PRK10973 171 DELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGeGTTEWNQV 250

                        250       260
                 ....*....|....*....|....*.
gi 648465774 263 FAMSTLTLVPVFFFFLFFQRLLIEGI 288
Cdd:PRK10973 251 MAAMLLTLIPPVVIVLAMQRAFVRGL 276
malG PRK10998
maltose ABC transporter permease MalG;
26-294 8.05e-29

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 111.72  E-value: 8.05e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  26 LIIHALLIAASLLMLYPLLWMVSASVRPENeiFSSTSLIPSSIDFSSYARGwVGLDVSFG------------RFFWNSLV 93
Cdd:PRK10998  14 FATHLLLLGFIALIMFPLLMVIAISLREGN--FATGSLIPEQISWEHWKLA-LGFSVEHAdgrvtpppfpvlLWLWNSVK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  94 ISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLG------WVNTILPLVVpKFLAS 167
Cdd:PRK10998  91 VAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGqyipfiGLNTHGGVIF-AYLGG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 168 DAFFIFLMVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNDMNTYTIQLGL 247
Cdd:PRK10998 170 IALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGM 249

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 648465774 248 RTFVDSTSaSDWGGLFAMSTLTLVPVFFFFLFFQRLLIEGIATTGMK 294
Cdd:PRK10998 250 QQYLNPQN-YLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 20-284 1.96e-23

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 96.33  E-value: 1.96e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  20 RSLPASLIIHALLIAASLLMLYPLLWMVSASVRPEneifSSTSLIPSSIDFSSYARGWVglDVSFGRFFWNSLVISLLVV 99
Cdd:COG1177    1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDS----WFLTFPPEGFTLRWYAELFS--DPRLLDALLNSLLIALLST 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 100 TGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMVQFF 179
Cdd:COG1177   75 LLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLARL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 180 RGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPL-IYLNDMNTYTIQL--GLRTFVDSTSA 256
Cdd:COG1177  155 QGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLfLAGPGVTTLPVYIysMIRRGISPEIN 234

                        250       260
                 ....*....|....*....|....*...
gi 648465774 257 sdwgglfAMSTLTLVPVFFFFLFFQRLL 284
Cdd:COG1177  235 -------ALSTLLILLSLLLLLLAERLR 255
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
4-228 3.85e-16

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 76.71  E-value: 3.85e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774   4 MTASVTAARPPSDITKRSLPASLIIHALLIAAsLLMLYPLLWMVSASvrpeneiFSSTSLIpssidfsSYARGWVGLD-- 81
Cdd:COG1175    1 MTTTTSAAARRRRRRRRLAAYLFLLPALLLLL-VFVLYPLLYTLYLS-------FTDWNLL-------GPPPEFVGLDny 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  82 --VSFGRFFWNSLVISLLVVTGNVIACSLTAFAFARL---RFVGRNFWFAIMLGTLMIPYHVT-LIPQYVLFLDLGWVNT 155
Cdd:COG1175   66 arLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALLlnrKLRGRGFFRTLFFLPWVISPVVVaLIWKWLFNPDYGLLNA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 156 ILPLV---VPKFLASDAFFIFLMV-----QFF-----------RGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATA 216
Cdd:COG1175  146 LLGALglePINWLGDPSLALPAVIivtvwKGTgfnmliflaglQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFV 225

                        250
                 ....*....|..
gi 648465774 217 AIFSFIWTWDDF 228
Cdd:COG1175  226 LVLSTIGALQVF 237
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 88-273 2.51e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 72.70  E-value: 2.51e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  88 FWNSLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLAS 167
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 168 DAFFIFLMVQFFRG----IPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLNdMNTYTI 243
Cdd:cd06261   81 LLLIAPFARLIRRAalesIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG-GEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 648465774 244 QLGLRTFVDSTSASDWGGLFAMSTLTLVPV 273
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 15-224 1.03e-14

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 72.49  E-value: 1.03e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  15 SDITKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSstslIPSSIDFSSYARgwVGLDVSFGRFFWNSLVI 94
Cdd:COG1176    2 SAALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGG----VVPGFTLENYAR--LFTDPLYLKVLLRTLWI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  95 SLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTIL--------PLvvpKFLA 166
Cdd:COG1176   76 ALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLlalglidePL---RLLY 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 167 SDAFFIFLMVQFF------------RGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWT 224
Cdd:COG1176  153 TEFAVVIGLVYVYlpfmvlplyaalEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPA 222
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
18-233 3.40e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 72.50  E-value: 3.40e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  18 TKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPeneifsstslipssiDFSSYARGWvgLDVSFGRFFWNSLVISLL 97
Cdd:COG1178    3 TRPRRRPRLLLLLLALLLALLVLLPLLALLLRAFTD---------------GLANFWALL--SDPYLWRALGNTLLLALL 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  98 VVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLAS---------- 167
Cdd:COG1178   66 VTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRALFGLEPPDiyglggiilv 145

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 648465774 168 DAFFIF-----LMVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLI 233
Cdd:COG1178  146 LVLFNYpyvylLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLV 216
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-271 4.78e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 4.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  108 LTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLASDAFFIFLMVQFFRGIPRELD 187
Cdd:pfam00528   4 LGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  188 EAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLIYLND--MNTYTIQLGLRTFVDSTSASDWGGLFAM 265
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpgLGLLLIEAILGYDYPEIQGPVLAAALIL 163


                  ....*.
gi 648465774  266 STLTLV 271
Cdd:pfam00528 164 LLLNLL 169
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-222 6.92e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 62.49  E-value: 6.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774   6 ASVTAARPPSDITKRSLPASLIIHALLIAASLLMLYPLLWMVSASVRPeneifsstsLIPSSIDFSSYARgwVGLDVSFG 85
Cdd:COG1178  269 ATVGGRARRPRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTK---------ALDDNLTLDNYRF--VLLDPSLL 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  86 RFFWNSLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIP-------YHVTLIPQYVLFLDLGWVNTILP 158
Cdd:COG1178  338 RALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPgivlglgLLLLFNRPLPLLLYGTLAILVLA 417

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 648465774 159 LVVpKFLAsdafFIFLMVQ-FFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFI 222
Cdd:COG1178  418 YVV-RFLP----FALRSLEaALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFV 477
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 88-221 4.91e-08

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 52.83  E-value: 4.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  88 FWNSLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLAS 167
Cdd:COG0555   56 LKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIKVAFT 135

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 648465774 168 DA------FFIFL-----MVQ-FFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSF 221
Cdd:COG0555  136 PLgivlaqTFVSLpfvvrTVQpVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF 201
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 88-227 8.57e-08

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 52.29  E-value: 8.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  88 FWNSLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFLAS 167
Cdd:PRK09500  59 AQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAHITFC 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 168 DAFFIFLMVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDD 227
Cdd:PRK09500 139 LPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSFTLSLDD 198
cysT CHL00187
sulfate transport protein; Provisional
 91-221 2.07e-04

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 41.92  E-value: 2.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  91 SLVISLLVVTGNVIACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLVVPKFL----- 165
Cdd:CHL00187  60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGIQIVftklg 139

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 648465774 166 -------ASDAFFIFLMVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSF 221
Cdd:CHL00187 140 vllamifVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTF 202
modB PRK09421
molybdate ABC transporter permease subunit;
89-221 4.82e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 40.68  E-value: 4.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  89 WNSLVISLlVVTGNVIACSL-----TAFAFARLRFVGRNFWFAIMLGTLMIPYHVTlipQYVLFLDLG-------WVNTI 156
Cdd:PRK09421   8 WQAVLLSL-KVSSVAVLFSLpfgilVAWLLARCRFPGKSLLDSLLHLPLVLPPVVT---GYLLLISMGrrgfigqWLYEW 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 648465774 157 LPLVVP-----KFLASDAFFIFLMVQFFR----GIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSF 221
Cdd:PRK09421  84 FGISFAfswrgAALAAAVMAFPLMVRAIRlsleAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAF 157
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 88-225 5.16e-04

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 40.90  E-value: 5.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  88 FWNSLVISLL-VVTGNVIACSL---TAFAFARLRFVgRNFWFAIMLGTLMIPyHVTLIPQYVLFLDLGWVNTILPLVVPK 163
Cdd:COG0600   59 LWEHLLASLLrVLLGFALAALLgvpLGLLLGLSRLL-RRLLDPLLVFLRPIP-PLALAPLLILWFGIGEASKIFVIFLGA 136

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 648465774 164 FlasdaFFIFLMVQF-FRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTW 225
Cdd:COG0600  137 F-----FPILLNTAAgVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW 194
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 24-233 2.05e-03

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 39.66  E-value: 2.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774   24 ASLIIHALLIAASLLMLYPLLWMVSASVRPENEIFSSTSlipssiDFSSYARgwvglDVSFGRFFWNSLVISLLVVTGNV 103
Cdd:TIGR03262   3 ARLLLAGMILALLLFLLLPLLALLTKSVYDSDGDFIGLA------NFAEYFA-----TPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774  104 IACSLTAFAFARLRFVGRNFWFAIMLGTLMIPYHVTLIPQYVLFLDLGWVNTILPLV----VPKFLASDAFFIF-----L 174
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFsiygFWGIVIGEVFYTFphalmI 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 648465774  175 MVQFFRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVMATAAIFSFIWTWDDFFGPLI 233
Cdd:TIGR03262 152 LVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 145-222 4.50e-03

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 37.73  E-value: 4.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648465774 145 VLFLDLGWVNTILPLVVpkfLAsdaffIFLMVQF----FRGIPRELDEAAMMDGCSAWRIYWKIMLPLSLPVM------- 213
Cdd:COG1174   75 IPLLGIGPAPAIIALVL---YA-----LLPILRNtytgLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVIlagirta 146

                         90
                 ....*....|....
gi 648465774 214 -----ATAAIFSFI 222
Cdd:COG1174  147 avqniGTATLAALI 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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