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Conserved domains on  [gi|644369543|ref|WP_025305042|]
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MULTISPECIES: peroxide/acid stress response protein YhcN [Serratia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-87 2.96e-50

peroxide/acid stress response protein YhcN;


:

Pssm-ID: 411360  Cd Length: 87  Bit Score: 152.88  E-value: 2.96e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543  1 MNMKTTLAALGLLSVISFGASAAQLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIEARNEGNYH 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAAQSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNWH 80


                ....*..
gi 644369543 81 ATAEIYK 87
Cdd:NF033776 81 ATAELYK 87
 
Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-87 2.96e-50

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 152.88  E-value: 2.96e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543  1 MNMKTTLAALGLLSVISFGASAAQLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIEARNEGNYH 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAAQSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNWH 80


                ....*..
gi 644369543 81 ATAEIYK 87
Cdd:NF033776 81 ATAELYK 87
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 34-86 2.99e-18

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 71.01  E-value: 2.99e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 644369543  34 LQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIEAR--NEGNYHATAEIY 86
Cdd:pfam07338  1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADepNGGNWHGTAELY 55
PRK14864 PRK14864
biofilm peroxide resistance protein BsmA;
23-87 3.25e-11

biofilm peroxide resistance protein BsmA;


Pssm-ID: 184866  Cd Length: 104  Bit Score: 54.28  E-value: 3.25e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 644369543  23 AQLVTNDQTANLQSIGTITVSgIDGAPTDIRQALSEKADAKGATAYRVI---EARNEGNYHATAEIYK 87
Cdd:PRK14864  37 AQEIRRAQTQGLQKMGTVSAL-VRGSPDDAEREIQAKANAAGADYYVIVmvdETVVPGQWYSQAILYR 103
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-87 6.73e-11

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 56.26  E-value: 6.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543   1 MNMKTTLAALGLLSVIS--FGASAAQLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVI---EARN 75
Cdd:NF040471   1 MKLKNTILASALLLSLTalSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIQdtnDVNN 80

                         90
                 ....*....|..
gi 644369543  76 EGNYHATAEIYK 87
Cdd:NF040471  81 SGNWRVTADLYH 92
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 29-87 1.08e-05

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 41.62  E-value: 1.08e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 644369543  29 DQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAY---RVIEARNEGNYHATAEIYK 87
Cdd:NF040471 116 DEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFfivRQVDANSGGNQSITAYIYK 177
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 24-87 1.06e-03

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 35.84  E-value: 1.06e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 644369543  24 QLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIE--ARNEGNYHATAEIYK 87
Cdd:NF040471 252 EEVNNITAAQMVPFDSITFTGHFSSMTDVSYQVAKRAAKKGAKYYHITRqwQSNGGNLTISADLFK 317
 
Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-87 2.96e-50

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 152.88  E-value: 2.96e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543  1 MNMKTTLAALGLLSVISFGASAAQLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIEARNEGNYH 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAAQSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNWH 80


                ....*..
gi 644369543 81 ATAEIYK 87
Cdd:NF033776 81 ATAELYK 87
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 34-86 2.99e-18

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 71.01  E-value: 2.99e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 644369543  34 LQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIEAR--NEGNYHATAEIY 86
Cdd:pfam07338  1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADepNGGNWHGTAELY 55
PRK14864 PRK14864
biofilm peroxide resistance protein BsmA;
23-87 3.25e-11

biofilm peroxide resistance protein BsmA;


Pssm-ID: 184866  Cd Length: 104  Bit Score: 54.28  E-value: 3.25e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 644369543  23 AQLVTNDQTANLQSIGTITVSgIDGAPTDIRQALSEKADAKGATAYRVI---EARNEGNYHATAEIYK 87
Cdd:PRK14864  37 AQEIRRAQTQGLQKMGTVSAL-VRGSPDDAEREIQAKANAAGADYYVIVmvdETVVPGQWYSQAILYR 103
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-87 6.73e-11

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 56.26  E-value: 6.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543   1 MNMKTTLAALGLLSVIS--FGASAAQLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVI---EARN 75
Cdd:NF040471   1 MKLKNTILASALLLSLTalSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIQdtnDVNN 80

                         90
                 ....*....|..
gi 644369543  76 EGNYHATAEIYK 87
Cdd:NF040471  81 SGNWRVTADLYH 92
PRK09929 PRK09929
hypothetical protein; Provisional
 3-87 3.40e-09

hypothetical protein; Provisional


Pssm-ID: 182151  Cd Length: 91  Bit Score: 48.75  E-value: 3.40e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543  3 MKTTLAALGLLSVISFGASAAQLVTNDQTANLQS----IGTITVSGiDGAPTDIRQALSEKADAKGATAYRVIEARNEGN 78
Cdd:PRK09929  2 KIISKMLLGALAFAVTNVYAAELMTKAEFEKVESqyekIGTISTSN-EMSTADAKEDLIKKADEKGADVLVLTSGQTDNK 80


                ....*....
gi 644369543 79 YHATAEIYK 87
Cdd:PRK09929 81 IHGTADIYK 89
PRK10259 PRK10259
hypothetical protein; Provisional
 3-87 5.81e-08

hypothetical protein; Provisional


Pssm-ID: 137782  Cd Length: 86  Bit Score: 45.48  E-value: 5.81e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644369543  3 MKTTLAALGLlSVISFGASAAQLVTNDQTANLQSIGTITVsgiDGAPT--DIRQALSEKADAKGATAYRVIEARNEGNYH 80
Cdd:PRK10259  4 INTVVAAMAL-STLSFGVFAAEPVTASQAQNMNKIGVVSA---DGASTldALEAKLAEKAAAAGASGYSITSATNNNKLS 79


                ....*..
gi 644369543 81 ATAEIYK 87
Cdd:PRK10259 80 GTAVIYK 86
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 29-87 1.08e-05

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 41.62  E-value: 1.08e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 644369543  29 DQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAY---RVIEARNEGNYHATAEIYK 87
Cdd:NF040471 116 DEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFfivRQVDANSGGNQSITAYIYK 177
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 24-87 1.06e-03

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 35.84  E-value: 1.06e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 644369543  24 QLVTNDQTANLQSIGTITVSGIDGAPTDIRQALSEKADAKGATAYRVIE--ARNEGNYHATAEIYK 87
Cdd:NF040471 252 EEVNNITAAQMVPFDSITFTGHFSSMTDVSYQVAKRAAKKGAKYYHITRqwQSNGGNLTISADLFK 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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