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Conserved domains on  [gi|644350875|ref|WP_025301848|]
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MULTISPECIES: glutamate/aspartate ABC transporter permease GltK [Serratia]

Protein Classification

glutamate/aspartate ABC transporter permease GltK( domain architecture ID 11487652)

glutamate/aspartate ABC transporter permease GltK is part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
1-224 1.44e-136

glutamate/aspartate ABC transporter permease GltK;


:

Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 381.87  E-value: 1.44e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   1 MYEFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVP 80
Cdd:PRK15107   1 MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  81 SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT 160
Cdd:PRK15107  81 GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 644350875 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV 224
Cdd:PRK15107 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKRTV 224
 
Name Accession Description Interval E-value
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
1-224 1.44e-136

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 381.87  E-value: 1.44e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   1 MYEFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVP 80
Cdd:PRK15107   1 MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  81 SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT 160
Cdd:PRK15107  81 GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 644350875 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV 224
Cdd:PRK15107 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKRTV 224
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 2-222 9.36e-74

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 222.64  E-value: 9.36e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   2 YEFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPS 81
Cdd:COG0765    1 MFFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  82 LlqqVLGLSPktdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQ 161
Cdd:COG0765   81 L---GIDLSP-----FVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNE 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 644350875 162 GIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:COG0765  153 FISLLKDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERR 213
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 4-222 1.46e-27

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 104.16  E-value: 1.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875    4 FDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLl 83
Cdd:TIGR03003   1 WDWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   84 qqvlGLSPKTdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGI 163
Cdd:TIGR03003  80 ----GIRLPA---LVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLV 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 644350875  164 VLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:TIGR03003 153 AMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 20-213 7.59e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 7.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  20 MVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLLQQVLGLSPktdirLIS 99
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL-----GLP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875 100 AMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLAD 179
Cdd:cd06261   76 ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE 155

                        170       180       190
                 ....*....|....*....|....*....|....
gi 644350875 180 FFRTASTIGERDGTQVEMILFAGFVYFVISLAAS 213
Cdd:cd06261  156 APGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 34-223 1.77e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.52  E-value: 1.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   34 GILWGTVLAVMRlspFKPISWFATLYVNLFRSVPlvmVLLWFYLVVPSLLQQVLGLSpktdirLISAMVAFSLFEAAYYS 113
Cdd:pfam00528   1 GIPLGIIAALRR---GRRLDRLLRPLIDLLQALP---SFVLAILLVVIAILSILGHG------ILPAIILALLGWAGYAR 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  114 EIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVL--SLADFFRTASTIGERD 191
Cdd:pfam00528  69 LIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgsWPGLGLLLIEAILGYD 148

                         170       180       190
                  ....*....|....*....|....*....|...
gi 644350875  192 GTQ-VEMILFAGFVYFVISLAASALVSYLKKRT 223
Cdd:pfam00528 149 YPEiQGPVLAAALILLLLNLLVDILQRLLDPRV 181
 
Name Accession Description Interval E-value
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
1-224 1.44e-136

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 381.87  E-value: 1.44e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   1 MYEFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVP 80
Cdd:PRK15107   1 MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  81 SLLQQVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLT 160
Cdd:PRK15107  81 GFLQNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 644350875 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRTV 224
Cdd:PRK15107 161 QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKRTV 224
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 2-222 9.36e-74

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 222.64  E-value: 9.36e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   2 YEFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPS 81
Cdd:COG0765    1 MFFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  82 LlqqVLGLSPktdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQ 161
Cdd:COG0765   81 L---GIDLSP-----FVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNE 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 644350875 162 GIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:COG0765  153 FISLLKDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERR 213
PRK15100 PRK15100
cystine ABC transporter permease;
9-222 1.14e-42

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 143.35  E-value: 1.14e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   9 IVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPsllQQVLG 88
Cdd:PRK15100   8 VIDSAPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLP---QFGIE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  89 LSPktdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQD 168
Cdd:PRK15100  85 LDP-----IPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKD 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 644350875 169 TSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:PRK15100 160 TSLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQ 213
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 4-222 6.78e-36

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 126.36  E-value: 6.78e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   4 FDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFY------- 76
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYyglgqfe 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  77 LVVPSLLQQVLGlSPktdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVP 156
Cdd:COG4160   81 WVRESWLWPLLR-DP-----WFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALP 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 644350875 157 LLLTQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:COG4160  155 AYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERR 220
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 3-222 1.67e-29

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 109.37  E-value: 1.67e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   3 EFDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSL 82
Cdd:PRK09494   2 QFDWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPMA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  83 LqqvlglspkTDIR---LISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLL 159
Cdd:PRK09494  82 F---------NDLRidpFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLG 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 644350875 160 TQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:PRK09494 153 NQWIISIKDTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERR 215
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 4-222 1.46e-27

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 104.16  E-value: 1.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875    4 FDWASIVPSFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLl 83
Cdd:TIGR03003   1 WDWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDI- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   84 qqvlGLSPKTdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGI 163
Cdd:TIGR03003  80 ----GIRLPA---LVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLV 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 644350875  164 VLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:TIGR03003 153 AMFKETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEAR 211
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
16-223 2.40e-22

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 91.28  E-value: 2.40e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  16 LLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLLQQVLG------- 88
Cdd:PRK11123   7 LASAAGMTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQLLLTLSDgftlnlg 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  89 ---LSPKTDIRLI------SAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLL 159
Cdd:PRK11123  87 fvqIPVQMDIENFevspflCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLG 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 644350875 160 TQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKRT 223
Cdd:PRK11123 167 NQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRA 230
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 12-118 2.38e-21

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 84.51  E-value: 2.38e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   12 SFPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLlqqVLGLSP 91
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI---GIRLSP 77

                          90       100
                  ....*....|....*....|....*..
gi 644350875   92 ktdirLISAMVAFSLFEAAYYSEIIRA 118
Cdd:TIGR01726  78 -----LTAAVIALTLFYGAYLAEIFRG 99
PRK15069 PRK15069
histidine ABC transporter permease HisM;
17-222 9.46e-18

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 78.55  E-value: 9.46e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  17 LQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLlqQVLGLSPKTDIR 96
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSL--EIVRGTDLLDAF 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  97 LISAM----VAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLV 172
Cdd:PRK15069  98 FRSGLnctiLAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLA 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 644350875 173 YVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:PRK15069 178 FTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERR 227
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
16-222 5.81e-16

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 73.67  E-value: 5.81e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  16 LLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVP-LVMVLLWFY--LVVPSLLQQVLGLSPK 92
Cdd:PRK15135   9 ILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPdLVLMLLIFYglQIALNSVTEALGVGQI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  93 TDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLV 172
Cdd:PRK15135  89 DIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALV 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 644350875 173 YVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:PRK15135 169 SLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERR 218
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 20-213 7.59e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 7.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  20 MVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVPLVMVLLWFYLVVPSLLQQVLGLSPktdirLIS 99
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL-----GLP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875 100 AMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLAD 179
Cdd:cd06261   76 ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE 155

                        170       180       190
                 ....*....|....*....|....*....|....
gi 644350875 180 FFRTASTIGERDGTQVEMILFAGFVYFVISLAAS 213
Cdd:cd06261  156 APGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
artM PRK11122
arginine ABC transporter permease ArtM;
13-222 7.95e-14

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 67.68  E-value: 7.95e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  13 FPFLLQGMVITLKITVTAIVVGILWGTVLAVMRLSPFKPISWFATLYVNLFRSVP-LVMVLLWFY-------LVVPSLLQ 84
Cdd:PRK11122   5 LPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPlLVQIFLIYYgpgqfpwLQEYPWLW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  85 QVLGLSpktdirLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRlVILPQAFRAMVPLLLTQGIV 164
Cdd:PRK11122  85 HLLSQP------WLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875 165 LFQDTSLVYVLSLADFFRTASTIgerDGTQVEMILF--AGFVYFVISLAASALVSYLKKR 222
Cdd:PRK11122 158 VFKSTSLAYTITLMDVMGYSQLL---YGRTYDVMVFgaAGIIYLVVNGLLTLLMRLIERK 214
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 34-223 1.77e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.52  E-value: 1.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   34 GILWGTVLAVMRlspFKPISWFATLYVNLFRSVPlvmVLLWFYLVVPSLLQQVLGLSpktdirLISAMVAFSLFEAAYYS 113
Cdd:pfam00528   1 GIPLGIIAALRR---GRRLDRLLRPLIDLLQALP---SFVLAILLVVIAILSILGHG------ILPAIILALLGWAGYAR 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  114 EIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMVPLLLTQGIVLFQDTSLVYVL--SLADFFRTASTIGERD 191
Cdd:pfam00528  69 LIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgsWPGLGLLLIEAILGYD 148

                         170       180       190
                  ....*....|....*....|....*....|...
gi 644350875  192 GTQ-VEMILFAGFVYFVISLAASALVSYLKKRT 223
Cdd:pfam00528 149 YPEiQGPVLAAALILLLLNLLVDILQRLLDPRV 181
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
60-155 1.29e-03

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 38.56  E-value: 1.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  60 VNLFRSVPLVMVLLWfylVVPsLLQQVLGlspkTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHW 139
Cdd:PRK10782  60 VNIFRSIPFIILLVW---MIP-FTRVIVG----TSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPM 131

                         90
                 ....*....|....*.
gi 644350875 140 QSMRLVILPQAFRAMV 155
Cdd:PRK10782 132 QIVRKVLLPEALPGLV 147
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 16-150 1.64e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.59  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875  16 LLQGMVITLKITVTAIVVGILWGTVLAVMrLSPFKPISWFATLYVNLFRSVPLV----MVLLWFylvvpsllqqvlGLSP 91
Cdd:COG0600   59 LWEHLLASLLRVLLGFALAALLGVPLGLL-LGLSRLLRRLLDPLLVFLRPIPPLalapLLILWF------------GIGE 125

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 644350875  92 KTDIRLISAMVAFSLFEAAYyseiirAGIISISRGQSSAALALGMTHWQSMRLVILPQA 150
Cdd:COG0600  126 ASKIFVIFLGAFFPILLNTA------AGVRSVDPELLELARSLGASRWQILRKVVLPAA 178
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 115-222 4.42e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 37.38  E-value: 4.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875 115 IIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAF------------RA----MVPLLLTQGIVLFQdtslvyvLSLA 178
Cdd:COG0573  174 LSRDALRAVPRSLREAALALGATRWETIRKVVLPAARsgiiaavilglgRAlgetMAVLMVAGNAPQIP-------FSLF 246

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 644350875 179 DFFRT-----ASTIGE--RDGTQVEMILFAGFVYFVISLAASALVSYLKKR 222
Cdd:COG0573  247 DPGRTltaliALEFGEapFGSLHYSALFALGLVLFVITLLVNLLARLIVRR 297
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 13-222 6.55e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 36.86  E-value: 6.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   13 FPFLLQGMVITLKITVTAIVVGIlwGTVLAVMRLSPFKPISWFATLyVNLFRSVPLVMVLLW-FYLVVPSL-------LQ 84
Cdd:TIGR02138  62 LPLIVGTLITSLIALLIAVPVGI--GIAIFLSEIAPKRVRSVLKPV-VELLAGIPSVVYGFWgLFVLVPFLkphfqpfLG 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 644350875   85 QVLGLSPKTDIRLISAMVAFSLFEAAYYSEIIRAGIISISRGQSSAALALGMTHWQSMRLVILPQAFRAMV-PLLLTQG- 162
Cdd:TIGR02138 139 SNLGLIPLFGGPILTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVgAVVLGLGr 218

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 644350875  163 ------IVLFQdTSLVYVLSLADFFRTASTI--------GERDGTQVEM-ILFA-GFVYFVISLAASALVSYLKKR 222
Cdd:TIGR02138 219 algetmAVTMV-IGNVFPISPLSLFDPGTTItslianqfGEASGGSVHTsALFAlGLVLFVITLLVNILARYIVRR 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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