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Conserved domains on  [gi|639691373|ref|WP_024720390|]
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MULTISPECIES: biofilm surface layer hydrophobin BslA [Bacillus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BslA pfam17735
Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). ...
 46-166 4.84e-49

Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). Secreted BslA from Bacillus subtillis has been shown to form surface layers around the biofilm self-assembling at interfaces of B. subtilis biofilms, forming an elastic film. structural analysis revealed that BslA consists of an Ig-type fold with the addition of an unusual, extremely hydrophobic cap region. The hydrophobic cap exhibits physiochemical properties similar to the hydrophobic surface found in fungal hydrophobins; thus, BslA is defined as member of a class of bacterially produced hydrophobins.


:

Pssm-ID: 407610  Cd Length: 121  Bit Score: 154.51  E-value: 4.84e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639691373   46 LYAKITGAskQEWSFSDIDLTYRPNSVLSIGAVEFTLPAGFQATTKDIING----KALKDSYILNNGKTVRIPaRFDLFG 121
Cdd:pfam17735   1 LEASPTNS--KEWSTSDIELTYTPNSVMSNGTVEFTLPDGFTATTKDTVKGngteNALNTTQILNNGRTVRIP-GLNLLG 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 639691373  122 SSQYTLQLSHKVLPAAGTYTFRAENRAISIGSTFYaEDTIDINKR 166
Cdd:pfam17735  78 GSKIKLKLANKTLPDAGTYTFRAEADADGIGSKFP-ESGLEIESR 121
 
Name Accession Description Interval E-value
BslA pfam17735
Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). ...
 46-166 4.84e-49

Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). Secreted BslA from Bacillus subtillis has been shown to form surface layers around the biofilm self-assembling at interfaces of B. subtilis biofilms, forming an elastic film. structural analysis revealed that BslA consists of an Ig-type fold with the addition of an unusual, extremely hydrophobic cap region. The hydrophobic cap exhibits physiochemical properties similar to the hydrophobic surface found in fungal hydrophobins; thus, BslA is defined as member of a class of bacterially produced hydrophobins.


Pssm-ID: 407610  Cd Length: 121  Bit Score: 154.51  E-value: 4.84e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639691373   46 LYAKITGAskQEWSFSDIDLTYRPNSVLSIGAVEFTLPAGFQATTKDIING----KALKDSYILNNGKTVRIPaRFDLFG 121
Cdd:pfam17735   1 LEASPTNS--KEWSTSDIELTYTPNSVMSNGTVEFTLPDGFTATTKDTVKGngteNALNTTQILNNGRTVRIP-GLNLLG 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 639691373  122 SSQYTLQLSHKVLPAAGTYTFRAENRAISIGSTFYaEDTIDINKR 166
Cdd:pfam17735  78 GSKIKLKLANKTLPDAGTYTFRAEADADGIGSKFP-ESGLEIESR 121
BslA_like cd14670
Bacterial immunoglobulin-like hydrophobin BslA and similar proteins; BslA (YuaB) is a protein ...
 43-162 7.68e-39

Bacterial immunoglobulin-like hydrophobin BslA and similar proteins; BslA (YuaB) is a protein from Bacillus subtilis acting as a hydrophobin, which forms surface layers around biofilms and participates in biofilm assembly. BslA contains an unusually hydrophobic "cap structure", which is essential for its activity and for the ability of bacteria to form hydrophobic, non-wetting biofilms. A number of domains in various proteins from Bacilli and other bacterial lineages appear related to BslA, but do not conserve the hydrophobic cap.


Pssm-ID: 270614  Cd Length: 128  Bit Score: 129.00  E-value: 7.68e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639691373  43 PAALYAKITGASKQ--EWSFSDIDLTYRPNSVLSIGAVEFTLPAGFQATTKDIING-----KALKDSYILNNGKTVRIPA 115
Cdd:cd14670    1 PAALSGTLTLSPANgtAGTTSDIVLTYTAGQRSPNGTVEFTLPAGITATLTDTTTVnivglKTLTKQSIGRTGTTYSYSK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639691373 116 RFDLFGSSQYTLQLSHKVLPAAGTYTFRAENRAISIG-STFYAEDTID 162
Cdd:cd14670   81 VGALLAASGIVLTLSNKDRPAAGTYTFKVIVDADGIGdYTFPAEYTTT 128
 
Name Accession Description Interval E-value
BslA pfam17735
Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). ...
 46-166 4.84e-49

Biofilm surface layer A; This family includes members such as BslA (previously called YuaB). Secreted BslA from Bacillus subtillis has been shown to form surface layers around the biofilm self-assembling at interfaces of B. subtilis biofilms, forming an elastic film. structural analysis revealed that BslA consists of an Ig-type fold with the addition of an unusual, extremely hydrophobic cap region. The hydrophobic cap exhibits physiochemical properties similar to the hydrophobic surface found in fungal hydrophobins; thus, BslA is defined as member of a class of bacterially produced hydrophobins.


Pssm-ID: 407610  Cd Length: 121  Bit Score: 154.51  E-value: 4.84e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639691373   46 LYAKITGAskQEWSFSDIDLTYRPNSVLSIGAVEFTLPAGFQATTKDIING----KALKDSYILNNGKTVRIPaRFDLFG 121
Cdd:pfam17735   1 LEASPTNS--KEWSTSDIELTYTPNSVMSNGTVEFTLPDGFTATTKDTVKGngteNALNTTQILNNGRTVRIP-GLNLLG 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 639691373  122 SSQYTLQLSHKVLPAAGTYTFRAENRAISIGSTFYaEDTIDINKR 166
Cdd:pfam17735  78 GSKIKLKLANKTLPDAGTYTFRAEADADGIGSKFP-ESGLEIESR 121
BslA_like cd14670
Bacterial immunoglobulin-like hydrophobin BslA and similar proteins; BslA (YuaB) is a protein ...
 43-162 7.68e-39

Bacterial immunoglobulin-like hydrophobin BslA and similar proteins; BslA (YuaB) is a protein from Bacillus subtilis acting as a hydrophobin, which forms surface layers around biofilms and participates in biofilm assembly. BslA contains an unusually hydrophobic "cap structure", which is essential for its activity and for the ability of bacteria to form hydrophobic, non-wetting biofilms. A number of domains in various proteins from Bacilli and other bacterial lineages appear related to BslA, but do not conserve the hydrophobic cap.


Pssm-ID: 270614  Cd Length: 128  Bit Score: 129.00  E-value: 7.68e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 639691373  43 PAALYAKITGASKQ--EWSFSDIDLTYRPNSVLSIGAVEFTLPAGFQATTKDIING-----KALKDSYILNNGKTVRIPA 115
Cdd:cd14670    1 PAALSGTLTLSPANgtAGTTSDIVLTYTAGQRSPNGTVEFTLPAGITATLTDTTTVnivglKTLTKQSIGRTGTTYSYSK 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 639691373 116 RFDLFGSSQYTLQLSHKVLPAAGTYTFRAENRAISIG-STFYAEDTID 162
Cdd:cd14670   81 VGALLAASGIVLTLSNKDRPAAGTYTFKVIVDADGIGdYTFPAEYTTT 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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