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Conserved domains on  [gi|636785341|ref|WP_024321550|]
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ABC transporter permease [Rhizobium ruizarguesonis]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-312 2.42e-89

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.01  E-value: 2.42e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNNpqnGFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGP---RATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQ 165
Cdd:COG0601   79 TSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 166 LGVFRVIEPDSFWATLFA--------AIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLP 237
Cdd:COG0601  159 LGWLPVSGRVSPWEDFLDalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIP 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 636785341 238 VVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVKL 312
Cdd:COG0601  239 VVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-312 2.42e-89

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.01  E-value: 2.42e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNNpqnGFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGP---RATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQ 165
Cdd:COG0601   79 TSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 166 LGVFRVIEPDSFWATLFA--------AIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLP 237
Cdd:COG0601  159 LGWLPVSGRVSPWEDFLDalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIP 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 636785341 238 VVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVKL 312
Cdd:COG0601  239 VVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 6-311 6.72e-48

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 163.35  E-value: 6.72e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPiTNVLNNPQngfTQEEIKEIIAAQ-GLDKPIPVQLWTSFSGFVTGDL 84
Cdd:PRK15081   2 LNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDP-ARLAAGPE---ADAQVVALVRQQlGLDQPLPHQFWHYISNALQGDF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  85 GLSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGF 164
Cdd:PRK15081  78 GTSMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 165 QLGVFRVIEPDSFWATLFAAIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIAL 244
Cdd:PRK15081 158 ELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGL 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636785341 245 TIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVK 311
Cdd:PRK15081 238 QFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 129-311 3.91e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 80.81  E-value: 3.91e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  129 FLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFqlgvfrviepDSFWATLFAAIALGIPISAQIAEVLIANLDHESG 208
Cdd:pfam00528  10 LRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------SILGHGILPAIILALLGWAGYARLIRRAALRSLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  209 QEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLA 288
Cdd:pfam00528  80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAA 159

                         170       180
                  ....*....|....*....|...
gi 636785341  289 AVVFVIVNLIADLAYPLLDPRVK 311
Cdd:pfam00528 160 ALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 102-295 1.44e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.60  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 102 LPSTLVLASAGLVTALILAAVIAYGTQFLPKRfGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQLGVFrvIEPDSFWATL 181
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK-LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWG--ILPGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 182 FAAIALGIPISAQIAEVLIANLDhesgQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFG 261
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIP----KDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 636785341 262 --RTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIV 295
Cdd:cd06261  154 geAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 6-312 2.42e-89

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 270.01  E-value: 2.42e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNNpqnGFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:COG0601    2 LRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGP---RATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQ 165
Cdd:COG0601   79 TSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 166 LGVFRVIEPDSFWATLFA--------AIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLP 237
Cdd:COG0601  159 LGWLPVSGRVSPWEDFLDalrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIP 238

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 636785341 238 VVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVKL 312
Cdd:COG0601  239 VVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 6-311 6.72e-48

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 163.35  E-value: 6.72e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPiTNVLNNPQngfTQEEIKEIIAAQ-GLDKPIPVQLWTSFSGFVTGDL 84
Cdd:PRK15081   2 LNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDP-ARLAAGPE---ADAQVVALVRQQlGLDQPLPHQFWHYISNALQGDF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  85 GLSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGF 164
Cdd:PRK15081  78 GTSMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 165 QLGVFRVIEPDSFWATLFAAIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIAL 244
Cdd:PRK15081 158 ELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGL 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636785341 245 TIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVK 311
Cdd:PRK15081 238 QFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 6-312 4.49e-44

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 153.70  E-value: 4.49e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNNPQNGFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:PRK10352   2 LRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQ 165
Cdd:PRK10352  82 ISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 166 LGVFRVIEPDSFWATLFAAIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALT 245
Cdd:PRK10352 162 LQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMH 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636785341 246 IGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVKL 312
Cdd:PRK10352 242 IGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRR 308
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
6-311 1.33e-29

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 115.68  E-value: 1.33e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNnpQNGFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:PRK10914   2 LQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAG--ERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILA------AVIAYGTQFLPKRFGQGLlRGFpslflSVPNFVIGLVLI 159
Cdd:PRK10914  80 ISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGipvgvlAAVKRGSIFDHTAVGLAL-TGY-----SMPIFWWGMMLI 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 160 HLFGFQLGV---------------------FRVI------EPDSF----WATLFAAIALGIPISAQIAEVLIANLDHESG 208
Cdd:PRK10914 154 MLVSVHWNLtpvsgrvsdmvflddsnpltgFMLIdtaiwgEDGNFidavAHMILPAIVLGTIPLAVIVRMTRSSMLEVLG 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 209 QEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLA 288
Cdd:PRK10914 234 EDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLV 313

                        330       340
                 ....*....|....*....|...
gi 636785341 289 AVVFVIVNLIADLAYPLLDPRVK 311
Cdd:PRK10914 314 ATMIILVNLLVDLLYGVVNPRIR 336
oppB PRK09471
oligopeptide ABC transporter permease OppB;
6-311 3.66e-22

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 94.75  E-value: 3.66e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341   6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITNVLNNPQngftqEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLG 85
Cdd:PRK09471   2 LKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPP-----EVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  86 LSMR-TNRPVTTLIAEVLPSTLVLASAGLVTALIL---AAVIAYGTQFLPKRFgqgLLRGFPSLFLSVPNFVIGLVLIHL 161
Cdd:PRK09471  77 PSFKyKDYSVNDLVASSFPVSAKLGAAAFFLAVILgvsAGVIAALKQNTKWDY---TVMGFAMTGVVIPSFVVAPLLVLI 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 162 FGFQLGVFrviePDSFWA------TLFAAIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSS 235
Cdd:PRK09471 154 FAITLHWL----PGGGWNggalkfMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPAL 229

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 636785341 236 LPVVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRVK 311
Cdd:PRK09471 230 LPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 129-311 3.91e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 80.81  E-value: 3.91e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  129 FLPKRFGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFqlgvfrviepDSFWATLFAAIALGIPISAQIAEVLIANLDHESG 208
Cdd:pfam00528  10 LRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------SILGHGILPAIILALLGWAGYARLIRRAALRSLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  209 QEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAVVSLA 288
Cdd:pfam00528  80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAA 159

                         170       180
                  ....*....|....*....|...
gi 636785341  289 AVVFVIVNLIADLAYPLLDPRVK 311
Cdd:pfam00528 160 ALILLLLNLLVDILQRLLDPRVR 182
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 6-109 2.88e-12

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 62.62  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341    6 LNYAAKRLVQAIVVILLAYVFTFVVVSILPGDPITnvLNNPQNgFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGD-- 83
Cdd:pfam19300   2 LRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPAR--LACGKN-CTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdf 78

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 636785341   84 ----------LGLSMRTNRPVTTLIAEVLPSTLVLA 109
Cdd:pfam19300  79 gavghcpapcLGYSFANNEPVWDTIMDRFPTTLSLA 114
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 49-310 3.53e-11

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 63.61  E-value: 3.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  49 GFTQEEIKEIIAAQGLDKPIPVQLWTSFSGFVTGDLGLSMRTNRPVTTLIAEVLPSTLVLasaGLVTALILAAVIaygtq 128
Cdd:PRK15133  80 GLDPEVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITL---GLWSTLIIYLVS----- 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 129 fLPKRFGQGLLRGFP-----SLFL----SVPNFVIGLVLIHLF--GFQLGVFRV---IEP------------DSFWATLF 182
Cdd:PRK15133 152 -IPLGIRKAVRNGSRfdvwsSAFIiigyAIPAFLFAILLIVFFagGSYFDLFPLrglVSAnfdslpwyqkitDYLWHITL 230

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 183 AAIALGIPISAQIAEVLIANLDHESGQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALT-IGELLGGSLITETVFG 261
Cdd:PRK15133 231 PVLATVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATfISMFFTGSLLIEVMFS 310

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 636785341 262 RTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIVNLIADLAYPLLDPRV 310
Cdd:PRK15133 311 LNGLGLLGYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 102-295 1.44e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 59.60  E-value: 1.44e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 102 LPSTLVLASAGLVTALILAAVIAYGTQFLPKRfGQGLLRGFPSLFLSVPNFVIGLVLIHLFGFQLGVFrvIEPDSFWATL 181
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK-LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWG--ILPGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 182 FAAIALGIPISAQIAEVLIANLDhesgQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFG 261
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIP----KDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 636785341 262 --RTGLGSLVQRSVSTQDLPVLQAVVSLAAVVFVIV 295
Cdd:cd06261  154 geAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK15110 PRK15110
peptide ABC transporter permease SapB;
76-308 1.43e-09

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 58.55  E-value: 1.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  76 FSGFVTGDLGLSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQGLLRGFPSLFLSVPNFVIG 155
Cdd:PRK15110  48 FNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLA 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 156 LVLIHLFGFQLGVFRV---------IEPDSFWATLFA----------------------AIALGIPISAQIAEVLIANLD 204
Cdd:PRK15110 128 LLLTLFFSLTLGWLPVsgrfdllyeVKPVTGFALIDAwlsdspwrdemimsairhmilpVITLAVAPTTEVIRLMRISTI 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 205 HESGQEYAAVARGRGLSQMRLFAKHLLKPSSLPVVTVIALTIGELLGGSLITETVFGRTGLGSLVQRSVSTQDLPVLQAV 284
Cdd:PRK15110 208 EVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAG 287

                        250       260
                 ....*....|....*....|....
gi 636785341 285 VSLAAVVFVIVNLIADLAYPLLDP 308
Cdd:PRK15110 288 VMVVGSLVIIVNVLSDILGAMANP 311
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 106-266 4.81e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 4.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 106 LVLASAGLVTALILAAVIAYgtqfLPKRFGQGLLRgFPSLFLSVPNFVIGLVLIHLFGFqlgvfrviepdSFWATLFAAI 185
Cdd:COG1173   86 LLAVLIALVIGVLLGLLAGY----FGGWVDAVLMR-LVDVLLAFPSLLLAIALVAVLGP-----------GLLNVILALG 149

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 186 ALGIPISAQI--AEVLIanldhESGQEYAAVARGRGLSQMRLFAKHLLkPSSLPVVTVIAlTIGelLGGSLITETVFGRT 263
Cdd:COG1173  150 LTGWPGYARLvrAQVLS-----LREREYVEAARALGASPLRIIFRHIL-PNVLPPLIVQA-TLG--IASAILAEAGLSFL 220


                 ...
gi 636785341 264 GLG 266
Cdd:COG1173  221 GLG 223
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
72-234 2.45e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 39.37  E-value: 2.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341  72 LWTSFSGFVTGDLGLSMRTNRPVTTLIAEVLPSTLVLASAGLVTALILAAVIAYGTQFLPKRFGQgLLRGFPSLFLSVPN 151
Cdd:COG1178  310 LLWSLTKALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLAR-LLDRLAMLPYAVPG 388

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636785341 152 FVIGLVLIHLFGFQLGVFRViepDSFWATLFAAIALGIPISAQIAEVLIANLDhesgQEYAAVARGRGLSQMRLFAK--- 228
Cdd:COG1178  389 IVLGLGLLLLFNRPLPLLLY---GTLAILVLAYVVRFLPFALRSLEAALAQID----PSLEEAARSLGASPLRTLRRvtl 461


                 ....*.
gi 636785341 229 HLLKPS 234
Cdd:COG1178  462 PLLRPG 467
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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