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AraC family transcriptional regulator [Rhizobium ruizarguesonis]

Protein Classification

AraC family transcriptional regulator( domain architecture ID 13722860)

AraC family transcriptional regulator contains a helix-turn-helix DNA-binding motif and controls the expression of genes with diverse biological functions including metabolism, stress response, and virulence

Gene Ontology:  GO:0003700|GO:0006355|GO:0043565

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 24-173 2.35e-58

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


:

Pssm-ID: 461994  Cd Length: 152  Bit Score: 184.24  E-value: 2.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494   24 AIPRVGLLRAERTTEPTAGMTELVICLVLQGAKAITCGENVLHYGGGSYFVASVEVPVFGRISEASLQKPFLGVGFSFDA 103
Cdd:pfam06719   1 AIPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEVTEASPEEPYLGLALDLDP 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636783494  104 RNIADLLIEMPDVH-DPEFLCGLGVSPTDPQLEEAFLRMMRLLDRPNEISVMAPMIEREILFRLLRGPQGA 173
Cdd:pfam06719  81 ALLAELLLEAPPPGpPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGA 151
GlxA super family cl34854
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 179-292 6.03e-27

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


The actual alignment was detected with superfamily member COG4977:

Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 107.55  E-value: 6.03e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 179 AQIDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVA 258
Cdd:COG4977  203 VPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIA 282

                         90       100       110
                 ....*....|....*....|....*....|....
gi 636783494 259 FAVGYESASQFSREYGRLFGLPPARDASRLRAKP 292
Cdd:COG4977  283 AACGFGSASHFRRAFRRRFGVSPSAYRRRFRARA 316
 
Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 24-173 2.35e-58

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


Pssm-ID: 461994  Cd Length: 152  Bit Score: 184.24  E-value: 2.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494   24 AIPRVGLLRAERTTEPTAGMTELVICLVLQGAKAITCGENVLHYGGGSYFVASVEVPVFGRISEASLQKPFLGVGFSFDA 103
Cdd:pfam06719   1 AIPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEVTEASPEEPYLGLALDLDP 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636783494  104 RNIADLLIEMPDVH-DPEFLCGLGVSPTDPQLEEAFLRMMRLLDRPNEISVMAPMIEREILFRLLRGPQGA 173
Cdd:pfam06719  81 ALLAELLLEAPPPGpPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGA 151
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 179-292 6.03e-27

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 107.55  E-value: 6.03e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 179 AQIDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVA 258
Cdd:COG4977  203 VPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIA 282

                         90       100       110
                 ....*....|....*....|....*....|....
gi 636783494 259 FAVGYESASQFSREYGRLFGLPPARDASRLRAKP 292
Cdd:COG4977  283 AACGFGSASHFRRAFRRRFGVSPSAYRRRFRARA 316
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
65-292 1.01e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.15  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494  65 LHYGGGSYFVASVEVPVFGRISEASLQKPFLGVGFSFDARNIADLLIEMPDVHDPEFLCGLGVSPTDPQLEEAFLRMMRL 144
Cdd:COG2207   27 LILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 145 LDRPNEISVMAPMIEREILFRLLRGPQGA----KLRQIAQIDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFH 220
Cdd:COG2207  107 LLLLLLLLLLLLLLLLLLLLLLALLRALEllllLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLS 186

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 636783494 221 RHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREYGRLFGLPPARDASRLRAKP 292
Cdd:COG2207  187 RLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
204-281 1.58e-21

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 86.45  E-value: 1.58e-21
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 636783494   204 KVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREYGRLFGLPP 281
Cdd:smart00342   3 TLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80
HTH_18 pfam12833
Helix-turn-helix domain;
208-283 1.16e-20

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 84.18  E-value: 1.16e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636783494  208 LARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGD-AARVAFAVGYESASQFSREYGRLFGLPPAR 283
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTGLsVAEIALALGFSDASHFSRAFRRLFGLTPSE 77
ftrA PRK09393
transcriptional activator FtrA; Provisional
 182-282 1.16e-14

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 73.07  E-value: 1.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 182 DGRQSQ-VRRALA------------WIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLL 248
Cdd:PRK09393 201 DGGQAQfVPRPVAsresdrlgplidWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLE 280

                         90       100       110
                 ....*....|....*....|....*....|....
gi 636783494 249 ETPGDAARVAFAVGYESASQFSREYGRLFGLPPA 282
Cdd:PRK09393 281 SSALSIDQIAERAGFGSEESLRHHFRRRAATSPA 314
 
Name Accession Description Interval E-value
AraC_N pfam06719
AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of ...
 24-173 2.35e-58

AraC-type transcriptional regulator N-terminus; This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.


Pssm-ID: 461994  Cd Length: 152  Bit Score: 184.24  E-value: 2.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494   24 AIPRVGLLRAERTTEPTAGMTELVICLVLQGAKAITCGENVLHYGGGSYFVASVEVPVFGRISEASLQKPFLGVGFSFDA 103
Cdd:pfam06719   1 AIPGLTLFRTSEPTEPTPVVYEPSLCIVAQGAKRVHLGDETYEYDPGEYLVVSVDLPVTGEVTEASPEEPYLGLALDLDP 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636783494  104 RNIADLLIEMPDVH-DPEFLCGLGVSPTDPQLEEAFLRMMRLLDRPNEISVMAPMIEREILFRLLRGPQGA 173
Cdd:pfam06719  81 ALLAELLLEAPPPGpPPRAGRGLAVSPLDEELLDAVLRLLRLLDTPEDIPVLAPLILREILYRLLTGPQGA 151
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 179-292 6.03e-27

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 107.55  E-value: 6.03e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 179 AQIDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVA 258
Cdd:COG4977  203 VPLGHRDPRLARAQAWMEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIA 282

                         90       100       110
                 ....*....|....*....|....*....|....
gi 636783494 259 FAVGYESASQFSREYGRLFGLPPARDASRLRAKP 292
Cdd:COG4977  283 AACGFGSASHFRRAFRRRFGVSPSAYRRRFRARA 316
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
65-292 1.01e-21

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 92.15  E-value: 1.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494  65 LHYGGGSYFVASVEVPVFGRISEASLQKPFLGVGFSFDARNIADLLIEMPDVHDPEFLCGLGVSPTDPQLEEAFLRMMRL 144
Cdd:COG2207   27 LILLLLALVLLLLLLALLLLLLLLLGLLGGLLLLLLLLLLLGLLLLLLLLLLGLLLLALLALLLLVGLLLLLLLLLLLLL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 145 LDRPNEISVMAPMIEREILFRLLRGPQGA----KLRQIAQIDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFH 220
Cdd:COG2207  107 LLLLLLLLLLLLLLLLLLLLLLALLRALEllllLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTLEELARELGLSPRTLS 186

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 636783494 221 RHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREYGRLFGLPPARDASRLRAKP 292
Cdd:COG2207  187 RLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVTPSEYRKRLRARA 258
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
204-281 1.58e-21

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 86.45  E-value: 1.58e-21
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 636783494   204 KVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREYGRLFGLPP 281
Cdd:smart00342   3 TLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 183-290 3.64e-21

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 92.04  E-value: 3.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 183 GRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRlLLETPGDAARVAFAVG 262
Cdd:COG2169   81 PRADLVARACRLIEAGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQ-LLQTGLSVTDAAYAAG 159

                         90       100
                 ....*....|....*....|....*...
gi 636783494 263 YESASQFSREYGRLFGLPPardaSRLRA 290
Cdd:COG2169  160 FGSLSRFYEAFKKLLGMTP----SAYRR 183
HTH_18 pfam12833
Helix-turn-helix domain;
208-283 1.16e-20

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 84.18  E-value: 1.16e-20
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 636783494  208 LARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGD-AARVAFAVGYESASQFSREYGRLFGLPPAR 283
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEDTGLsVAEIALALGFSDASHFSRAFRRLFGLTPSE 77
ftrA PRK09393
transcriptional activator FtrA; Provisional
 182-282 1.16e-14

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 73.07  E-value: 1.16e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 182 DGRQSQ-VRRALA------------WIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLL 248
Cdd:PRK09393 201 DGGQAQfVPRPVAsresdrlgplidWMRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLE 280

                         90       100       110
                 ....*....|....*....|....*....|....
gi 636783494 249 ETPGDAARVAFAVGYESASQFSREYGRLFGLPPA 282
Cdd:PRK09393 281 SSALSIDQIAERAGFGSEESLRHHFRRRAATSPA 314
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
159-281 2.77e-13

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 68.55  E-value: 2.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 159 EREILF-RLLrgpqgAKLRQIAQI---DGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQY 234
Cdd:PRK13503 145 SREILFmQLL-----VLLRKSSLQengENSDARLNQLLAWLEDHFAEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRY 219

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 636783494 235 QKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREYGRLFGLPP 281
Cdd:PRK13503 220 LNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREFSWSP 266
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 195-236 2.24e-08

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 49.46  E-value: 2.24e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 636783494  195 IRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQK 236
Cdd:pfam00165   1 LRENLSTNLTIADIADELGFSRSYFSRLFKKYTGVTPSQYRH 42
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
166-282 2.96e-07

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 51.13  E-value: 2.96e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 166 LLRGPQGAKLRQIAQIDGRqsqVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARR 245
Cdd:PRK10572 166 LLRCMEAIPESLHPPMDPR---VREACQYISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKL 242

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 636783494 246 LLLETPGDAARVAFAVGYESASQFSREYGRLFGLPPA 282
Cdd:PRK10572 243 LLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPS 279
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
194-282 3.43e-06

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 45.30  E-value: 3.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 194 WIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSREY 273
Cdd:PRK10219  13 WIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVF 92


                 ....*....
gi 636783494 274 GRLFGLPPA 282
Cdd:PRK10219  93 RRQFDRTPS 101
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
192-283 2.36e-05

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 43.17  E-value: 2.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 192 LAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFAVGYESASQFSR 271
Cdd:PRK11511  15 LDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTR 94

                         90
                 ....*....|..
gi 636783494 272 EYGRLFGLPPAR 283
Cdd:PRK11511  95 TFKNYFDVPPHK 106
PRK15435 PRK15435
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
205-281 5.86e-05

bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;


Pssm-ID: 185333 [Multi-domain]  Cd Length: 353  Bit Score: 44.01  E-value: 5.86e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 636783494 205 VEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRlheARRL--LLETPGDAARVAFAVGYESASQFSREYGRLFGLPP 281
Cdd:PRK15435 102 LEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWR---ARRLreALAKGESVTTSILNAGFPDSSSYYRKADETLGMTA 177
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
181-283 6.92e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 43.89  E-value: 6.92e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 181 IDGRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLLETPGDAARVAFA 260
Cdd:PRK13502 171 ATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQ 250

                         90       100
                 ....*....|....*....|...
gi 636783494 261 VGYESASQFSREYGRLFGLPPAR 283
Cdd:PRK13502 251 CGFEDSNYFSVVFTRETGMTPSQ 273
PRK10130 PRK10130
HTH-type transcriptional regulator EutR;
183-282 1.97e-04

HTH-type transcriptional regulator EutR;


Pssm-ID: 182258 [Multi-domain]  Cd Length: 350  Bit Score: 42.60  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 183 GRQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRFRLHEARRLLL------ETPGDAar 256
Cdd:PRK10130 237 SYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNAFHAILGIGPNAWLKRIRLNAVRRELIspwsqsTTVKDA-- 314

                         90       100
                 ....*....|....*....|....*.
gi 636783494 257 vAFAVGYESASQFSREYGRLFGLPPA 282
Cdd:PRK10130 315 -AMQWGFWHLGQFATDYQQLFAEKPS 339
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 109-282 1.25e-03

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 40.05  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 109 LLIEMPDVHDPEflcglgVSPTDPQL----EEAFLRMMRLLDRPNEiSVMAPMIEREILFRLLRG-----PQGAKL-RQI 178
Cdd:PRK15186 105 FLYEHADFSAPL------TKPTTKHLlapiETGVARVFNLLHSSNK-SQKLSQDKKEYLIRFLLSefiyePEAFALfREL 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636783494 179 AQidgrQSQVRRALAWIRENFTESFKVEDLARMTGMSASVFHRHFKAATTMTPIQYQKRfRLHEARRLLLETPGDAARVA 258
Cdd:PRK15186 178 SQ----NTLAENIYNIIISDISRKWALKDISDSLYMSCSTLKRKLKQENTSFSEVYLNA-RMNKATKLLRNSEYNITRVA 252

                        170       180
                 ....*....|....*....|....
gi 636783494 259 FAVGYESASQFSREYGRLFGLPPA 282
Cdd:PRK15186 253 YMCGYDSASYFTCVFKKHFKTTPS 276
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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